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carbamates and Tuberculosis, Pulmonary

carbamates has been researched along with Tuberculosis, Pulmonary in 6 studies

Tuberculosis, Pulmonary: MYCOBACTERIUM infections of the lung.

Research Excerpts

ExcerptRelevanceReference
" Bioisosteric replacement of this biaryl moiety by arylpiperazine resulted in a soluble, orally bioavailable carbamate analogue providing identical activity in the acute model, comparable efficacy to OPC-67683 in a chronic infection model, favorable pharmacokinetic profiles across several species, and enhanced safety."1.38Structure-activity relationships for amide-, carbamate-, and urea-linked analogues of the tuberculosis drug (6S)-2-nitro-6-{[4-(trifluoromethoxy)benzyl]oxy}-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazine (PA-824). ( Blaser, A; Denny, WA; Franzblau, SG; Kmentova, I; Ma, Z; Palmer, BD; Sutherland, HS; Thompson, AM; Wan, B; Wang, Y, 2012)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19905 (83.33)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Blaser, A1
Palmer, BD1
Sutherland, HS1
Kmentova, I1
Franzblau, SG1
Wan, B1
Wang, Y1
Ma, Z1
Thompson, AM1
Denny, WA1
BROUET, G1
MARCHE, J1
BETOURNE, C1
RESTELLINI, J1
Keleberda, KIa1
Svistunova, AS1
Kaminskaia, GO1
Kordonskaia, VM1
Makinskiĭ, AI3
Safarov, RN2
Fondaminskaia, LD1
Semenova, AS1
Fedotova, NN1

Trials

1 trial available for carbamates and Tuberculosis, Pulmonary

ArticleYear
[Effectiveness of pyridinolcarbamate in the overall treatment of infiltrative and cavernous-fibrous pulmonary tuberculosis].
    Problemy tuberkuleza, 1979, Issue:1

    Topics: Adult; Aged; Carbamates; Clinical Trials as Topic; Drug Evaluation; Humans; Male; Middle Aged; Pyrid

1979

Other Studies

5 other studies available for carbamates and Tuberculosis, Pulmonary

ArticleYear
Structure-activity relationships for amide-, carbamate-, and urea-linked analogues of the tuberculosis drug (6S)-2-nitro-6-{[4-(trifluoromethoxy)benzyl]oxy}-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazine (PA-824).
    Journal of medicinal chemistry, 2012, Jan-12, Volume: 55, Issue:1

    Topics: Acute Disease; Amides; Animals; Antitubercular Agents; Biological Availability; Biphenyl Compounds;

2012
[Preliminary study on the chemotherapy of chronic pulmonary tuberculosis with a monosubstituted sulfone (1.500 F) administered alone or in association with streptomycin].
    Revue de la tuberculose, 1950, Volume: 14, Issue:1/2

    Topics: Carbamates; Pyrazoles; Streptomycin; Strobilurins; Sulfones; Tuberculosis; Tuberculosis, Pulmonary

1950
[Use of the antikinin preparation prodectin in the complex treatment of pulmonary tuberculosis patients].
    Problemy tuberkuleza, 1982, Issue:10

    Topics: Adolescent; Adult; Aged; Antitubercular Agents; Carbamates; Humans; Kinins; Middle Aged; Pyridinolca

1982
[Indications for using antikinin preparations and blood kinin system activators in the combined treatment of pulmonary tuberculosis].
    Problemy tuberkuleza, 1981, Issue:10

    Topics: Antitubercular Agents; Carbamates; Drug Therapy, Combination; Enzyme Activation; Humans; Kinins; Pyr

1981
[Use of prodectin in pulmonary tuberculosis].
    Vrachebnoe delo, 1981, Issue:11

    Topics: Adult; Aged; Carbamates; Humans; Kinins; Middle Aged; Pyridinolcarbamate; Tuberculosis, Pulmonary

1981