carbamates has been researched along with Tuberculosis, Pulmonary in 6 studies
Tuberculosis, Pulmonary: MYCOBACTERIUM infections of the lung.
Excerpt | Relevance | Reference |
---|---|---|
" Bioisosteric replacement of this biaryl moiety by arylpiperazine resulted in a soluble, orally bioavailable carbamate analogue providing identical activity in the acute model, comparable efficacy to OPC-67683 in a chronic infection model, favorable pharmacokinetic profiles across several species, and enhanced safety." | 1.38 | Structure-activity relationships for amide-, carbamate-, and urea-linked analogues of the tuberculosis drug (6S)-2-nitro-6-{[4-(trifluoromethoxy)benzyl]oxy}-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazine (PA-824). ( Blaser, A; Denny, WA; Franzblau, SG; Kmentova, I; Ma, Z; Palmer, BD; Sutherland, HS; Thompson, AM; Wan, B; Wang, Y, 2012) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 5 (83.33) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 1 (16.67) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Blaser, A | 1 |
Palmer, BD | 1 |
Sutherland, HS | 1 |
Kmentova, I | 1 |
Franzblau, SG | 1 |
Wan, B | 1 |
Wang, Y | 1 |
Ma, Z | 1 |
Thompson, AM | 1 |
Denny, WA | 1 |
BROUET, G | 1 |
MARCHE, J | 1 |
BETOURNE, C | 1 |
RESTELLINI, J | 1 |
Keleberda, KIa | 1 |
Svistunova, AS | 1 |
Kaminskaia, GO | 1 |
Kordonskaia, VM | 1 |
Makinskiĭ, AI | 3 |
Safarov, RN | 2 |
Fondaminskaia, LD | 1 |
Semenova, AS | 1 |
Fedotova, NN | 1 |
1 trial available for carbamates and Tuberculosis, Pulmonary
Article | Year |
---|---|
[Effectiveness of pyridinolcarbamate in the overall treatment of infiltrative and cavernous-fibrous pulmonary tuberculosis].
Topics: Adult; Aged; Carbamates; Clinical Trials as Topic; Drug Evaluation; Humans; Male; Middle Aged; Pyrid | 1979 |
5 other studies available for carbamates and Tuberculosis, Pulmonary
Article | Year |
---|---|
Structure-activity relationships for amide-, carbamate-, and urea-linked analogues of the tuberculosis drug (6S)-2-nitro-6-{[4-(trifluoromethoxy)benzyl]oxy}-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazine (PA-824).
Topics: Acute Disease; Amides; Animals; Antitubercular Agents; Biological Availability; Biphenyl Compounds; | 2012 |
[Preliminary study on the chemotherapy of chronic pulmonary tuberculosis with a monosubstituted sulfone (1.500 F) administered alone or in association with streptomycin].
Topics: Carbamates; Pyrazoles; Streptomycin; Strobilurins; Sulfones; Tuberculosis; Tuberculosis, Pulmonary | 1950 |
[Use of the antikinin preparation prodectin in the complex treatment of pulmonary tuberculosis patients].
Topics: Adolescent; Adult; Aged; Antitubercular Agents; Carbamates; Humans; Kinins; Middle Aged; Pyridinolca | 1982 |
[Indications for using antikinin preparations and blood kinin system activators in the combined treatment of pulmonary tuberculosis].
Topics: Antitubercular Agents; Carbamates; Drug Therapy, Combination; Enzyme Activation; Humans; Kinins; Pyr | 1981 |
[Use of prodectin in pulmonary tuberculosis].
Topics: Adult; Aged; Carbamates; Humans; Kinins; Middle Aged; Pyridinolcarbamate; Tuberculosis, Pulmonary | 1981 |