carbamates has been researched along with Retinal Degeneration in 6 studies
Retinal Degeneration: A retrogressive pathological change in the retina, focal or generalized, caused by genetic defects, inflammation, trauma, vascular disease, or aging. Degeneration affecting predominantly the macula lutea of the retina is MACULAR DEGENERATION. (Newell, Ophthalmology: Principles and Concepts, 7th ed, p304)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Calpains are activated by excessive light exposure and related to retinal degeneration." | 7.76 | Calpain inhibitor protects cells against light-induced retinal degeneration. ( Hara, H; Imai, S; Nakanishi, T; Shimazawa, M; Tsuruma, K, 2010) |
| "Our results suggested that orally available calpain inhibitor SNJ-1945 might be a possible candidate drug for testing in preventing progression of glaucomatous retinal degeneration." | 7.73 | Amelioration of retinal degeneration and proteolysis in acute ocular hypertensive rats by calpain inhibitor ((1S)-1-((((1S)-1-benzyl-3-cyclopropylamino-2,3-di-oxopropyl)amino)carbonyl)-3-methylbutyl)carbamic acid 5-methoxy-3-oxapentyl ester. ( Azuma, M; Nakajima, E; Oka, T; Shearer, TR; Tamada, Y; Tochigi, A; Walkup, RD, 2006) |
| " One hour after ocular hypertension (OH), SNJ-1945 was administrated as a single oral dose of 50 mg/kg." | 3.80 | Degeneration and dysfunction of retinal neurons in acute ocular hypertensive rats: involvement of calpains. ( Azuma, M; Oka, T; Shearer, TR; Suzuki, R; Tamada, Y, 2014) |
| "Calpains are activated by excessive light exposure and related to retinal degeneration." | 3.76 | Calpain inhibitor protects cells against light-induced retinal degeneration. ( Hara, H; Imai, S; Nakanishi, T; Shimazawa, M; Tsuruma, K, 2010) |
| "Our results suggested that orally available calpain inhibitor SNJ-1945 might be a possible candidate drug for testing in preventing progression of glaucomatous retinal degeneration." | 3.73 | Amelioration of retinal degeneration and proteolysis in acute ocular hypertensive rats by calpain inhibitor ((1S)-1-((((1S)-1-benzyl-3-cyclopropylamino-2,3-di-oxopropyl)amino)carbonyl)-3-methylbutyl)carbamic acid 5-methoxy-3-oxapentyl ester. ( Azuma, M; Nakajima, E; Oka, T; Shearer, TR; Tamada, Y; Tochigi, A; Walkup, RD, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (33.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 3 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Suzuki, R | 1 |
| Oka, T | 3 |
| Tamada, Y | 2 |
| Shearer, TR | 2 |
| Azuma, M | 2 |
| Shimazawa, M | 2 |
| Suemori, S | 1 |
| Inokuchi, Y | 1 |
| Matsunaga, N | 1 |
| Nakajima, Y | 1 |
| Yamamoto, T | 1 |
| Hara, H | 2 |
| Imai, S | 1 |
| Nakanishi, T | 1 |
| Tsuruma, K | 1 |
| NAKAMURA, GR | 1 |
| Walkup, RD | 1 |
| Nakajima, E | 1 |
| Tochigi, A | 1 |
| Pouliquen, Y | 1 |
| Guyot-Argenton, C | 1 |
6 other studies available for carbamates and Retinal Degeneration
| Article | Year |
|---|---|
Degeneration and dysfunction of retinal neurons in acute ocular hypertensive rats: involvement of calpains.
Topics: Acute Disease; Animals; Calpain; Carbamates; Male; Ocular Hypertension; Rats; Rats, Sprague-Dawley; | 2014 |
A novel calpain inhibitor, ((1S)-1-((((1S)-1-Benzyl-3-cyclopropylamino-2,3-di-oxopropyl)amino)carbonyl)-3-methylbutyl)carbamic acid 5-methoxy-3-oxapentyl ester (SNJ-1945), reduces murine retinal cell death in vitro and in vivo.
Topics: Administration, Oral; Animals; Calpain; Carbamates; Cell Line; Cell Survival; Glycoproteins; Injecti | 2010 |
Calpain inhibitor protects cells against light-induced retinal degeneration.
Topics: Animals; Apoptosis; Calpain; Carbamates; Caspase 3; Caspase 7; Electroretinography; Light; Male; Mic | 2010 |
The detection of 1-ethinyl cyciohexyl carbamate in toxicological specimens and its separation from a mixture of other drugs.
Topics: Carbamates; Humans; Hypnotics and Sedatives; Rare Diseases; Retinal Degeneration; Retinal Detachment | 1958 |
Amelioration of retinal degeneration and proteolysis in acute ocular hypertensive rats by calpain inhibitor ((1S)-1-((((1S)-1-benzyl-3-cyclopropylamino-2,3-di-oxopropyl)amino)carbonyl)-3-methylbutyl)carbamic acid 5-methoxy-3-oxapentyl ester.
Topics: Animals; Calcium-Binding Proteins; Calpain; Carbamates; Disease Models, Animal; Drug Administration | 2006 |
[Contribution of pyridinol-carbamate in ophthalmologic therapeutics].
Topics: Adult; Aged; Arteriosclerosis; Carbamates; Diabetic Retinopathy; Female; Humans; Male; Middle Aged; | 1972 |