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carbamates and Pulmonary Hypertension

carbamates has been researched along with Pulmonary Hypertension in 6 studies

Research Excerpts

ExcerptRelevanceReference
" Because Akt signaling is a potential molecular target of HIV protease inhibitors (HPIs), we hypothesized that these drugs altered monocrotaline- and hypoxia-induced PH in rats by downregulating the Akt pathway, thereby inhibiting pulmonary artery smooth muscle cell proliferation."7.76Effects of HIV protease inhibitors on progression of monocrotaline- and hypoxia-induced pulmonary hypertension in rats. ( Adnot, S; Amsellem, V; Brégeon, J; Dubois-Randé, JL; Gary-Bobo, G; Houssaini, A; Marcos, E; Pacaud, P; Perrin, A; Rideau, D; Savale, L; Sitbon, O, 2010)
" Among all the known isoforms of sPLA(2), sPLA(2)-X transcript was most significantly augmented in the pulmonary arteries of rats with monocrotaline-induced pulmonary hypertension (MCT-PHR)."3.78Role of secretory phospholipase A(2) in rhythmic contraction of pulmonary arteries of rats with monocrotaline-induced pulmonary arterial hypertension. ( Kamataki, A; Morikawa, Y; Nakayama, K; Saito-Tanji, M; Sawai, T; Tanabe, Y, 2012)
" Because Akt signaling is a potential molecular target of HIV protease inhibitors (HPIs), we hypothesized that these drugs altered monocrotaline- and hypoxia-induced PH in rats by downregulating the Akt pathway, thereby inhibiting pulmonary artery smooth muscle cell proliferation."3.76Effects of HIV protease inhibitors on progression of monocrotaline- and hypoxia-induced pulmonary hypertension in rats. ( Adnot, S; Amsellem, V; Brégeon, J; Dubois-Randé, JL; Gary-Bobo, G; Houssaini, A; Marcos, E; Pacaud, P; Perrin, A; Rideau, D; Savale, L; Sitbon, O, 2010)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19901 (16.67)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's5 (83.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Wenzel, D1
Matthey, M1
Bindila, L1
Lerner, R1
Lutz, B1
Zimmer, A1
Fleischmann, BK1
Renard, S1
Borentain, P1
Salaun, E1
Benhaourech, S1
Maille, B1
Darque, A1
Bregigeon, S1
Colson, P1
Laugier, D1
Gaubert, MR1
Habib, G1
Tran, TA1
Kramer, B1
Shin, YJ1
Vallar, P1
Boatman, PD1
Zou, N1
Sage, CR1
Gharbaoui, T1
Krishnan, A1
Pal, B1
Shakya, SR1
Garrido Montalban, A1
Adams, JW1
Ramirez, J1
Behan, DP1
Shifrina, A1
Blackburn, A1
Leakakos, T1
Shi, Y1
Morgan, M1
Sadeque, A1
Chen, W1
Unett, DJ1
Gaidarov, I1
Chen, X1
Chang, S1
Shu, HH1
Tung, SF1
Semple, G1
Gary-Bobo, G1
Houssaini, A1
Amsellem, V1
Rideau, D1
Pacaud, P1
Perrin, A1
Brégeon, J1
Marcos, E1
Dubois-Randé, JL1
Sitbon, O1
Savale, L1
Adnot, S1
Tanabe, Y1
Saito-Tanji, M1
Morikawa, Y1
Kamataki, A1
Sawai, T1
Nakayama, K1
Bülow, M1
Dell, HD1
Fiedler, J1
Kamp, R1
Lorenz, D1

Other Studies

6 other studies available for carbamates and Pulmonary Hypertension

ArticleYear
Endocannabinoid anandamide mediates hypoxic pulmonary vasoconstriction.
    Proceedings of the National Academy of Sciences of the United States of America, 2013, Nov-12, Volume: 110, Issue:46

    Topics: Amidohydrolases; Analysis of Variance; Animals; Arachidonic Acids; Benzamides; Blotting, Western; Ca

2013
Severe Pulmonary Arterial Hypertension in Patients Treated for Hepatitis C With Sofosbuvir.
    Chest, 2016, Volume: 149, Issue:3

    Topics: Antiviral Agents; Carbamates; Comorbidity; Drug Therapy, Combination; Female; Hepatitis C, Chronic;

2016
Discovery of 2-(((1r,4r)-4-(((4-Chlorophenyl)(phenyl)carbamoyl)oxy)methyl)cyclohexyl)methoxy)acetate (Ralinepag): An Orally Active Prostacyclin Receptor Agonist for the Treatment of Pulmonary Arterial Hypertension.
    Journal of medicinal chemistry, 2017, 02-09, Volume: 60, Issue:3

    Topics: Acetates; Administration, Oral; Animals; Biological Availability; Carbamates; Drug Discovery; Hypert

2017
Effects of HIV protease inhibitors on progression of monocrotaline- and hypoxia-induced pulmonary hypertension in rats.
    Circulation, 2010, Nov-09, Volume: 122, Issue:19

    Topics: Animals; Animals, Newborn; Antiretroviral Therapy, Highly Active; Antiviral Agents; Blood Pressure;

2010
Role of secretory phospholipase A(2) in rhythmic contraction of pulmonary arteries of rats with monocrotaline-induced pulmonary arterial hypertension.
    Journal of pharmacological sciences, 2012, Volume: 119, Issue:3

    Topics: Animals; Carbamates; Cyclooxygenase 2 Inhibitors; Hypertension, Pulmonary; Indolizines; Male; Monocr

2012
[Metabolism and distribution of chlorphentermine and clorofex in animal and man].
    Arzneimittel-Forschung, 1971, Volume: 21, Issue:1

    Topics: Adrenal Glands; Animals; Appetite Depressants; Biotransformation; Carbamates; Chlorphentermine; Dige

1971