carbamates has been researched along with Nerve Degeneration in 11 studies
Nerve Degeneration: Loss of functional activity and trophic degeneration of nerve axons and their terminal arborizations following the destruction of their cells of origin or interruption of their continuity with these cells. The pathology is characteristic of neurodegenerative diseases. Often the process of nerve degeneration is studied in research on neuroanatomical localization and correlation of the neurophysiology of neural pathways.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Here, we show that oral dosing with SNJ-1945, a novel water-soluble calpain inhibitor, reduces experimental autoimmune encephalomyelitis clinical scores in vivo and has a two pronged effect via anti-inflammation and protection against neurodegeneration." | 5.40 | Effects of a novel orally administered calpain inhibitor SNJ-1945 on immunomodulation and neurodegeneration in a murine model of multiple sclerosis. ( Azuma, M; Banik, NL; Beeson, C; Haque, A; Inoue, J; Smith, A; Trager, N; Wallace Iv, G, 2014) |
| " These results indicate that BPMC is highly toxic to zebrafish and that BPMC induces zebrafish developmental neurotoxicity through pathways involved in inflammation, oxidative stress, degeneration and apoptosis." | 1.56 | Fenobucarb-induced developmental neurotoxicity and mechanisms in zebrafish. ( Dai, MZ; Huang, YF; Li, CQ; Li, P; Wu, YY; Xia, B; Yang, H; Zhu, XY, 2020) |
| " Here, we show that oral dosing with SNJ-1945, a novel water-soluble calpain inhibitor, reduces experimental autoimmune encephalomyelitis clinical scores in vivo and has a two pronged effect via anti-inflammation and protection against neurodegeneration." | 1.40 | Effects of a novel orally administered calpain inhibitor SNJ-1945 on immunomodulation and neurodegeneration in a murine model of multiple sclerosis. ( Azuma, M; Banik, NL; Beeson, C; Haque, A; Inoue, J; Smith, A; Trager, N; Wallace Iv, G, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (18.18) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (27.27) | 29.6817 |
| 2010's | 3 (27.27) | 24.3611 |
| 2020's | 3 (27.27) | 2.80 |
| Authors | Studies |
|---|---|
| Zhu, XY | 1 |
| Wu, YY | 1 |
| Xia, B | 1 |
| Dai, MZ | 1 |
| Huang, YF | 1 |
| Yang, H | 1 |
| Li, CQ | 1 |
| Li, P | 1 |
| Queirós, L | 1 |
| Martins, AC | 1 |
| Krum, BN | 1 |
| Ke, T | 1 |
| Aschner, M | 1 |
| Pereira, JL | 1 |
| Gonçalves, FJM | 1 |
| Milne, GL | 1 |
| Pereira, P | 1 |
| Gordon, RY | 1 |
| Mikheeva, IB | 1 |
| Shubina, LV | 1 |
| Khutsian, SS | 1 |
| Kitchigina, VF | 1 |
| Trager, N | 1 |
| Smith, A | 1 |
| Wallace Iv, G | 1 |
| Azuma, M | 2 |
| Inoue, J | 1 |
| Beeson, C | 1 |
| Haque, A | 1 |
| Banik, NL | 1 |
| Rosenberger, TA | 1 |
| Tchantchou, F | 1 |
| Zhang, Y | 1 |
| Boscia, F | 1 |
| Annunziato, L | 1 |
| Taglialatela, M | 1 |
| Oka, T | 1 |
| Nakajima, T | 1 |
| Tamada, Y | 1 |
| Shearer, TR | 1 |
| Yagami, T | 1 |
| Ueda, K | 1 |
| Asakura, K | 1 |
| Hori, Y | 1 |
| Umehara, F | 1 |
| Izumo, S | 1 |
| Arimura, K | 1 |
| Osame, M | 1 |
| Igata, A | 1 |
| Williams, CH | 1 |
| Johnson, HJ | 1 |
| Casterline, JL | 1 |
11 other studies available for carbamates and Nerve Degeneration
| Article | Year |
|---|---|
Fenobucarb-induced developmental neurotoxicity and mechanisms in zebrafish.
Topics: Animals; Animals, Genetically Modified; Apoptosis; Behavior, Animal; Carbamates; Embryo, Nonmammalia | 2020 |
Assessing the neurotoxicity of the carbamate methomyl in Caenorhabditis elegans with a multi-level approach.
Topics: Animals; Animals, Genetically Modified; Caenorhabditis elegans; Carbamates; Cholinergic Neurons; Dos | 2021 |
Kainate-Induced Degeneration of Hippocampal Neurons. Protective Effect of Activation of the Endocannabinoid System.
Topics: Animals; Arachidonic Acids; Autophagosomes; Benzamides; CA3 Region, Hippocampal; Carbamates; Dentate | 2021 |
Effects of a novel orally administered calpain inhibitor SNJ-1945 on immunomodulation and neurodegeneration in a murine model of multiple sclerosis.
Topics: Animals; Blotting, Western; Calpain; Carbamates; Cell Proliferation; Cell Separation; Cysteine Prote | 2014 |
Targeting calpain-mediated proteolysis and peptide signaling as a strategy to reduce injury in multiple sclerosis.
Topics: Animals; Calpain; Carbamates; Cysteine Proteinase Inhibitors; Encephalomyelitis, Autoimmune, Experim | 2014 |
Selective inhibition of alpha/beta-hydrolase domain 6 attenuates neurodegeneration, alleviates blood brain barrier breakdown, and improves functional recovery in a mouse model of traumatic brain injury.
Topics: Animals; Arachidonic Acids; Biphenyl Compounds; Blood-Brain Barrier; Blotting, Western; Brain Injuri | 2013 |
Retigabine and flupirtine exert neuroprotective actions in organotypic hippocampal cultures.
Topics: Aminopyridines; Animals; Carbamates; Culture Media, Serum-Free; Glucose; Hippocampus; KCNQ Potassium | 2006 |
Contribution of calpains to photoreceptor cell death in N-methyl-N-nitrosourea-treated rats.
Topics: Animals; Calcium; Calpain; Carbamates; Cell Death; Cyclin-Dependent Kinase 5; Female; In Vitro Techn | 2007 |
Deterioration of axotomy-induced neurodegeneration by group IIA secretory phospholipase A2.
Topics: Animals; Animals, Newborn; Axotomy; Carbamates; Cell Death; Enzyme Inhibitors; Facial Nerve; Indoliz | 2001 |
[Polyneuropathy in carbamate (m-tolyl methylcarbamate) poisoning].
Topics: Carbamates; Female; Humans; Insecticides; Middle Aged; Nerve Degeneration; Peripheral Nervous System | 1987 |
Cholesterol content of spinal cord and sciatic nerve of hens after organophosphate and carbamate administration.
Topics: Animals; Carbamates; Cholesterol; Cholinesterase Inhibitors; In Vitro Techniques; Nerve Degeneration | 1966 |