carbamates has been researched along with Neoplasms in 69 studies
Neoplasms: New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Famotidine resulted in lower AUC while food had no effect." | 2.80 | Phase I study of XL281 (BMS-908662), a potent oral RAF kinase inhibitor, in patients with advanced solid tumors. ( Bendell, JC; Clary, DO; Dickson, MA; Edelman, G; Gordon, MS; Johnston, SH; Kudchadkar, RR; LoRusso, PM; Schwartz, GK, 2015) |
| " Dose-limiting toxic effects were reported at 660 mg/day (grade 3 elevation of hepatic transaminases [two patients] and QTc interval prolongation [one patient]), therefore the recommended maximum tolerated dose was 600 mg/day." | 2.77 | Phase I safety, pharmacokinetic and pharmacodynamic trial of BMS-599626 (AC480), an oral pan-HER receptor tyrosine kinase inhibitor, in patients with advanced solid tumors. ( Armand, JP; Baselga, J; Beliveau, M; Catteau, A; Cortes, J; De Andreis, D; James, J; Lopez, E; Marier, JF; Martell, RE; Massard, C; Ropert, S; Soria, JC, 2012) |
| " A revised formulation with micronized drug was more easily suspended and appeared to increase the bioavailability by a factor of 2-4." | 2.68 | Phase I trial and pharmacokinetics of the tubulin inhibitor 1069C85--a synthetic agent binding at the colchicine site designed to overcome multidrug resistance. ( Berry, C; Briasoulis, E; Hanwell, J; Judson, I; Lacey, H; Raynaud, F, 1997) |
| " Mean pharmacokinetic parameter values: T1/2 = 5." | 2.68 | A phase I trial and pharmacokinetic evaluation of CI-980 in patients with advanced solid tumors. ( Benson, L; Einzig, AI; Grove, WR; Lathia, CD; Roca, J; Sklarin, NT; Thomas, S; Wiernik, PH, 1997) |
| "Bay i 7433 (Copovithane) is a biological response modifier with antitumour activity in vivo, but no cytotoxic or cytostatic effect in vitro." | 2.66 | Clinical trial of high doses of Bay I 7433 (Copovithane). ( Danova, M; Faravelli, M; Girino, M; Riccardi, A; Salvini, P; Ucci, G, 1986) |
| "There are many anticancer drugs in the market, but their usefulness is limited because of drug resistance in a significant proportion of patients." | 2.58 | Double Edge Sword Behavior of Carbendazim: A Potent Fungicide With Anticancer Therapeutic Properties. ( Arya, R; Goyal, K; Gupta, GK; Sharma, A; Sharma, AK; Sharma, R, 2018) |
| "Liver cancer is one of the most common causes of cancer death worldwide." | 1.91 | PEGylated Liposomes Loaded with Carbamate Inhibitor ANP0903 Trigger Apoptosis by Enhancing ER Stress in HepG2 Cancer Cells. ( Armentano, MF; Bisaccia, F; Caddeo, C; Chiummiento, L; D'Orsi, R; Fadda, AM; Funicello, M; Lamorte, D; Lupattelli, P; Miglionico, R; Nigro, I; Rinaldi, R; Santoro, V; Valenti, D; Vassallo, A, 2023) |
| "The contemporary anticancer medications possess high attrition rates, bear substantial costs, and experience low efficacy owing to the drug resistance expressed by the aggressive tumors." | 1.72 | Benzimidazole-carbamate anthelmintics: Perspective candidates for the anticancer drug development. ( Prasher, P; Sharma, M, 2022) |
| "However, cancer cells evade such immune recognition by inducing proteolytic shedding of MICA/B proteins." | 1.56 | The fatty-acid amide hydrolase inhibitor URB597 inhibits MICA/B shedding. ( Funato, K; Koike, K; Miyakawa, Y; Otsuka, M; Seimiya, T; Sekiba, K; Tanaka, E, 2020) |
| "Data are sparse on treatment of chronic hepatitis C virus (HCV) in cancer patients." | 1.51 | Sofosbuvir-Based Therapy in Hepatitis C Virus-Infected Cancer Patients: A Prospective Observational Study. ( Angelidakis, G; Blechacz, B; Economides, MP; Granwehr, BP; Hosry, J; Jiang, Y; Kaseb, A; Kyvernitakis, A; Mahale, P; Miller, E; Naing, A; Raad, II; Samaniego, F; Torres, HA, 2019) |
| "Doxazolidine (Doxaz) is a functionally distinct formaldehyde conjugate of doxorubicin (Dox) that induces cancer cell death in Dox-sensitive and resistant cells." | 1.35 | Preclinical efficacy of a carboxylesterase 2-activated prodrug of doxazolidine. ( Barthel, BL; Chan, DC; Coldren, CD; Koch, GG; Koch, TH; Polinkovsky, M; Rudnicki, DL; Sun, H; Zhang, Z, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 30 (43.48) | 18.7374 |
| 1990's | 5 (7.25) | 18.2507 |
| 2000's | 7 (10.14) | 29.6817 |
| 2010's | 19 (27.54) | 24.3611 |
| 2020's | 8 (11.59) | 2.80 |
| Authors | Studies |
|---|---|
| Bresciani, G | 1 |
| Busto, N | 1 |
| Ceccherini, V | 1 |
| Bortoluzzi, M | 1 |
| Pampaloni, G | 1 |
| Garcia, B | 1 |
| Marchetti, F | 1 |
| Prasher, P | 1 |
| Sharma, M | 2 |
| Lei, H | 1 |
| Wang, X | 3 |
| Zhao, G | 1 |
| Li, T | 1 |
| Cui, Y | 1 |
| Wu, H | 1 |
| Yang, J | 1 |
| Jiang, N | 1 |
| Zhai, X | 1 |
| Caddeo, C | 1 |
| Miglionico, R | 1 |
| Rinaldi, R | 1 |
| Nigro, I | 1 |
| Lamorte, D | 1 |
| Chiummiento, L | 1 |
| Lupattelli, P | 1 |
| Funicello, M | 1 |
| D'Orsi, R | 1 |
| Valenti, D | 1 |
| Santoro, V | 1 |
| Fadda, AM | 1 |
| Bisaccia, F | 1 |
| Vassallo, A | 1 |
| Armentano, MF | 1 |
| Panwar, D | 1 |
| Tiwari, P | 1 |
| Kumar, A | 1 |
| Gautam, S | 1 |
| Marwaha, D | 1 |
| Rai, N | 1 |
| Singh, N | 1 |
| Bakshi, AK | 1 |
| Agarwal, N | 1 |
| Singh, NKC | 1 |
| Mitra, K | 1 |
| Prajapati, VM | 1 |
| Mishra, PR | 1 |
| Zhang, X | 2 |
| Sui, S | 1 |
| Wang, L | 1 |
| Li, H | 1 |
| Zhang, L | 2 |
| Xu, S | 1 |
| Zheng, X | 1 |
| Schrock, MS | 1 |
| Stromberg, BR | 1 |
| Scarberry, L | 1 |
| Summers, MK | 1 |
| Sekiba, K | 1 |
| Otsuka, M | 1 |
| Seimiya, T | 1 |
| Tanaka, E | 1 |
| Funato, K | 1 |
| Miyakawa, Y | 1 |
| Koike, K | 1 |
| Shan, X | 1 |
| Guo, L | 1 |
| Zhang, J | 3 |
| Ge, J | 1 |
| Jiang, Q | 1 |
| Ning, X | 1 |
| Torres, HA | 1 |
| Economides, MP | 1 |
| Angelidakis, G | 1 |
| Hosry, J | 1 |
| Kyvernitakis, A | 1 |
| Mahale, P | 1 |
| Jiang, Y | 1 |
| Miller, E | 1 |
| Blechacz, B | 1 |
| Naing, A | 1 |
| Samaniego, F | 1 |
| Kaseb, A | 1 |
| Raad, II | 1 |
| Granwehr, BP | 1 |
| Yang, C | 1 |
| Lee, A | 1 |
| Gao, S | 1 |
| Liu, S | 1 |
| Hedrick, JL | 1 |
| Yang, YY | 1 |
| Valente, S | 1 |
| Trisciuoglio, D | 1 |
| Tardugno, M | 1 |
| Benedetti, R | 1 |
| Labella, D | 1 |
| Secci, D | 1 |
| Mercurio, C | 1 |
| Boggio, R | 1 |
| Tomassi, S | 1 |
| Di Maro, S | 1 |
| Novellino, E | 1 |
| Altucci, L | 1 |
| Del Bufalo, D | 1 |
| Mai, A | 1 |
| Cosconati, S | 1 |
| Ait-Tihyaty, M | 1 |
| Rachid, Z | 1 |
| Larroque-Lombard, AL | 1 |
| Jean-Claude, BJ | 1 |
| Ge, X | 1 |
| Feng, J | 1 |
| Chen, S | 1 |
| Zhang, C | 1 |
| Ouyang, Y | 1 |
| Liu, Z | 1 |
| Yuan, W | 1 |
| Belum, VR | 1 |
| Rosen, AC | 1 |
| Jaimes, N | 1 |
| Dranitsaris, G | 1 |
| Pulitzer, MP | 1 |
| Busam, KJ | 1 |
| Marghoob, AA | 1 |
| Carvajal, RD | 1 |
| Chapman, PB | 1 |
| Lacouture, ME | 1 |
| Dickson, MA | 1 |
| Gordon, MS | 1 |
| Edelman, G | 1 |
| Bendell, JC | 1 |
| Kudchadkar, RR | 1 |
| LoRusso, PM | 1 |
| Johnston, SH | 1 |
| Clary, DO | 1 |
| Schwartz, GK | 1 |
| Hattori, Y | 1 |
| Hara, E | 1 |
| Shingu, Y | 1 |
| Minamiguchi, D | 1 |
| Nakamura, A | 1 |
| Arai, S | 1 |
| Ohno, H | 1 |
| Kawano, K | 1 |
| Fujii, N | 1 |
| Yonemochi, E | 1 |
| Kawatani, M | 1 |
| Osada, H | 1 |
| Kolakowski, RV | 1 |
| Haelsig, KT | 1 |
| Emmerton, KK | 1 |
| Leiske, CI | 1 |
| Miyamoto, JB | 1 |
| Cochran, JH | 1 |
| Lyon, RP | 1 |
| Senter, PD | 1 |
| Jeffrey, SC | 1 |
| Goyal, K | 1 |
| Sharma, A | 1 |
| Arya, R | 1 |
| Sharma, R | 1 |
| Gupta, GK | 1 |
| Sharma, AK | 1 |
| LARSEN, CD | 1 |
| Kapuriya, N | 1 |
| Kapuriya, K | 1 |
| Dong, H | 1 |
| Chou, TC | 1 |
| Chen, YT | 1 |
| Lee, TC | 1 |
| Lee, WC | 1 |
| Tsai, TH | 1 |
| Naliapara, Y | 1 |
| Su, TL | 1 |
| Ren, J | 2 |
| Lin, X | 2 |
| Barthel, BL | 1 |
| Zhang, Z | 1 |
| Rudnicki, DL | 1 |
| Coldren, CD | 1 |
| Polinkovsky, M | 1 |
| Sun, H | 1 |
| Koch, GG | 1 |
| Chan, DC | 1 |
| Koch, TH | 1 |
| André, S | 1 |
| Specker, D | 1 |
| Bovin, NV | 1 |
| Lensch, M | 1 |
| Kaltner, H | 1 |
| Gabius, HJ | 1 |
| Wittmann, V | 1 |
| Nathwani, SM | 1 |
| Butler, S | 1 |
| Fayne, D | 1 |
| McGovern, NN | 1 |
| Sarkadi, B | 1 |
| Meegan, MJ | 1 |
| Lloyd, DG | 1 |
| Campiani, G | 1 |
| Lawler, M | 1 |
| Williams, DC | 1 |
| Zisterer, DM | 1 |
| Manning, TJ | 1 |
| Williams, J | 1 |
| Jarrard, J | 1 |
| Gorman, T | 1 |
| von Schwarzenberg, K | 1 |
| Vollmar, AM | 1 |
| Giglio, J | 1 |
| Fernández, S | 1 |
| Rey, A | 1 |
| Cerecetto, H | 1 |
| Paterson, I | 1 |
| Naylor, GJ | 1 |
| Gardner, NM | 1 |
| Guzmán, E | 1 |
| Wright, AE | 1 |
| Soria, JC | 1 |
| Cortes, J | 1 |
| Massard, C | 1 |
| Armand, JP | 1 |
| De Andreis, D | 1 |
| Ropert, S | 1 |
| Lopez, E | 1 |
| Catteau, A | 1 |
| James, J | 1 |
| Marier, JF | 1 |
| Beliveau, M | 1 |
| Martell, RE | 1 |
| Baselga, J | 1 |
| Jin, Z | 1 |
| Pang, Y | 1 |
| Zhang, W | 1 |
| Huo, J | 1 |
| Zhang, Y | 1 |
| Siegfried, G | 1 |
| Basak, A | 1 |
| Cromlish, JA | 1 |
| Benjannet, S | 1 |
| Marcinkiewicz, J | 1 |
| Chrétien, M | 1 |
| Seidah, NG | 1 |
| Khatib, AM | 1 |
| FASSIO, E | 1 |
| BARDOS, TJ | 1 |
| PAPANASTASSIOU, ZB | 1 |
| SEGALOFF, A | 1 |
| AMBRUS, JL | 2 |
| GARCIA, H | 1 |
| FALKSON, G | 1 |
| DEJAGER, ME | 1 |
| VELASCO, HA | 1 |
| ROSS, CA | 1 |
| WEBSTER, JH | 1 |
| SOKAL, JE | 1 |
| STUTZMAN, L | 1 |
| WRIGHT, JC | 1 |
| LYONS, MM | 1 |
| WALKER, DG | 1 |
| GOLOMB, FM | 1 |
| GUMPORT, SL | 1 |
| MEDREK, TJ | 1 |
| MECHL, Z | 1 |
| KOLAR, V | 1 |
| KONECNY, M | 1 |
| MALCOMSON, KG | 1 |
| CORNMAN, I | 1 |
| Bergstralh, DT | 1 |
| Ting, JP | 1 |
| Judson, I | 1 |
| Briasoulis, E | 1 |
| Raynaud, F | 1 |
| Hanwell, J | 1 |
| Berry, C | 1 |
| Lacey, H | 1 |
| Markoglou, N | 1 |
| Wainer, IW | 1 |
| Sklarin, NT | 1 |
| Lathia, CD | 1 |
| Benson, L | 1 |
| Grove, WR | 1 |
| Thomas, S | 1 |
| Roca, J | 1 |
| Einzig, AI | 1 |
| Wiernik, PH | 1 |
| Rowinsky, EK | 1 |
| Long, GS | 1 |
| Noe, DA | 1 |
| Grochow, LB | 1 |
| Bowling, MK | 1 |
| Sartorius, SE | 1 |
| Donehower, RC | 1 |
| Gray, GM | 1 |
| Hammitt, JK | 1 |
| Elias, EG | 1 |
| Band, PR | 1 |
| Mittelman, A | 1 |
| Colsky, J | 1 |
| Regelson, W | 1 |
| Shnider, BI | 1 |
| Hanley, JA | 1 |
| Karev, NI | 1 |
| Garin, AM | 1 |
| Blokhina, NG | 1 |
| Pershin, MP | 1 |
| Trapeznikova, MF | 1 |
| Boger, DL | 1 |
| Invergo, BJ | 1 |
| Coleman, RS | 1 |
| Zarrinmayeh, H | 1 |
| Kitos, PA | 1 |
| Thompson, SC | 1 |
| Leong, T | 1 |
| McLaughlin, LW | 1 |
| Hortobagyi, GN | 2 |
| Hersh, EM | 1 |
| Papadopoulos, NE | 1 |
| Frye, D | 1 |
| Rios, A | 1 |
| Reuben, JM | 1 |
| Plager, C | 1 |
| Rosenblum, M | 1 |
| Quesada, J | 1 |
| Lalezari, I | 1 |
| Schwartz, EL | 1 |
| Ucci, G | 1 |
| Riccardi, A | 1 |
| Danova, M | 1 |
| Faravelli, M | 1 |
| Salvini, P | 1 |
| Girino, M | 1 |
| Rosenblum, MG | 1 |
| Pogosianz, HE | 1 |
| Prigogina, EL | 1 |
| Mirvish, SS | 1 |
| Lesobre, R | 1 |
| Ruffino, J | 1 |
| Tubiana, M | 1 |
| Criss, WE | 1 |
| Kurita, S | 1 |
| Nishimura, M | 1 |
| Ogawa, M | 1 |
| Kamei, Y | 1 |
| Ariyoshi, Y | 1 |
| Baba, T | 1 |
| Kimura, NT | 1 |
| Kanematsu, T | 1 |
| Aoki, K | 1 |
| Moore, GE | 1 |
| Bross, ID | 3 |
| Ausman, R | 1 |
| Nadler, S | 1 |
| Jones, R | 3 |
| Slack, N | 1 |
| Rimm, AA | 3 |
| Seidenglanz, G | 1 |
| Luce, JK | 1 |
| Bodey, GP | 1 |
| Saito, T | 1 |
| Oira, S | 1 |
| Wakui, A | 1 |
| Yokoyama, M | 1 |
| Takahashi, H | 1 |
| Carter, SK | 1 |
| Gorgun, B | 1 |
| Watne, AL | 1 |
| Slack, NH | 2 |
| Ausman, RK | 2 |
10 reviews available for carbamates and Neoplasms
| Article | Year |
|---|---|
APC/C ubiquitin ligase: Functions and mechanisms in tumorigenesis.
Topics: Anaphase-Promoting Complex-Cyclosome; Antigens, CD; Antineoplastic Agents; Carbamates; Cdc20 Protein | 2020 |
[Chemical biology and novel molecular-targeted agents in cancer therapy].
Topics: Aminoquinolines; Antineoplastic Agents; Carbamates; Cell Cycle; Coumarins; Diamines; Diterpenes, Kau | 2015 |
Double Edge Sword Behavior of Carbendazim: A Potent Fungicide With Anticancer Therapeutic Properties.
Topics: Animals; Antineoplastic Agents; Benzimidazoles; Carbamates; Cell Proliferation; Fungicides, Industri | 2018 |
Targeting apoptosis pathways by natural compounds in cancer: marine compounds as lead structures and chemical tools for cancer therapy.
Topics: Alkaloids; Alkanes; Animals; Anti-Bacterial Agents; Antineoplastic Agents; Apoptosis; Aquatic Organi | 2013 |
Microtubule stabilizing agents: their molecular signaling consequences and the potential for enhancement by drug combination.
Topics: Alkanes; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carbamates; | 2006 |
A demonstration of the intrinsic importance of stabilizing hydrophobic binding and non-covalent van der Waals contacts dominant in the non-covalent CC-1065/B-DNA binding.
Topics: Animals; Antibiotics, Antineoplastic; Base Sequence; Carbamates; Chemical Phenomena; Chemistry, Phys | 1990 |
Chromosome abnormalities and carcinogenesis.
Topics: Animals; Carbamates; Carcinogens; Chromosome Aberrations; Chromosome Disorders; Cricetinae; Down Syn | 1972 |
The carcinogenic action and metabolism of urethan and N-hydroxyurethan.
Topics: Adenoma; Animals; Animals, Newborn; Body Fluids; Breast Neoplasms; Carbamates; Carcinogens; Carcinom | 1968 |
A review of isozymes in cancer.
Topics: Animals; Aspartate Aminotransferases; Carbamates; Cell Transformation, Neoplastic; DNA Nucleotidyltr | 1971 |
[Chemotherapy of malignant tumors. 44].
Topics: Adrenal Cortex Hormones; Alkylating Agents; Androgens; Antibiotics, Antineoplastic; Antimetabolites; | 1970 |
13 trials available for carbamates and Neoplasms
| Article | Year |
|---|---|
Phase I study of XL281 (BMS-908662), a potent oral RAF kinase inhibitor, in patients with advanced solid tumors.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Area Under Curve; Benzimidazoles; Carbamates; | 2015 |
Phase I safety, pharmacokinetic and pharmacodynamic trial of BMS-599626 (AC480), an oral pan-HER receptor tyrosine kinase inhibitor, in patients with advanced solid tumors.
Topics: Administration, Oral; Adult; Aged; Antineoplastic Agents; Carbamates; ErbB Receptors; Female; Humans | 2012 |
Phase I trial and pharmacokinetics of the tubulin inhibitor 1069C85--a synthetic agent binding at the colchicine site designed to overcome multidrug resistance.
Topics: Administration, Oral; Adult; Aged; Antineoplastic Agents; Carbamates; Drug Administration Schedule; | 1997 |
Determination of the anticancer agent CI-980 in plasma by achiral liquid chromatography on a Pirkle-type stationary phase.
Topics: Antineoplastic Agents; Carbamates; Child; Chromatography, Liquid; Humans; Neoplasms; Pyrazines; Pyri | 1997 |
A phase I trial and pharmacokinetic evaluation of CI-980 in patients with advanced solid tumors.
Topics: Adult; Aged; Antineoplastic Agents; Area Under Curve; Biological Availability; Carbamates; Central N | 1997 |
Phase I and pharmacological study of CI-980, a novel synthetic antimicrotubule agent.
Topics: Adult; Aged; Antineoplastic Agents; Carbamates; Central Nervous System Diseases; Dose-Response Relat | 1997 |
Clinical evaluation of two weekly dose schedules of 'IC-140'. 4-N, N-bis (2-Chloroethyl) amino phenyl N (P-carboxyphenyl) carbamate, in the treatmentment of solid tumors 1,2.
Topics: Adenocarcinoma; Breast Neoplasms; Carbamates; Clinical Trials as Topic; Drug Administration Schedule | 1975 |
Clinical trial of high doses of Bay I 7433 (Copovithane).
Topics: Adult; Aged; Antineoplastic Agents; Carbamates; Clinical Trials as Topic; Female; Humans; Male; Midd | 1986 |
[Isoniazid and carcinogenesis].
Topics: Adenoma; Adult; Animals; Carbamates; Carcinoma; Child; Clinical Trials as Topic; Female; Humans; Hyd | 1969 |
Effects of meturedepa (NSC-51325) in 233 patients with advanced cancer. Eastern Clinical Drug Evaluation Program.
Topics: Alkylating Agents; Azirines; Breast Neoplasms; Carbamates; Clinical Trials as Topic; Female; Humans; | 1968 |
Initial clinical trials with 1,1-diphenyl-2-propynyl cyclohexanecarbamate (NCS-112682).
Topics: Alkynes; Antineoplastic Agents; Bone Marrow; Carbamates; Clinical Trials as Topic; Cyclohexanes; Eva | 1970 |
[Clinical experience with a new anticancer agent, carbazilquinone].
Topics: Adult; Aged; Antineoplastic Agents; Azirines; Carbamates; Clinical Trials as Topic; Female; Humans; | 1971 |
Porfiromycin (NSC-56410)--clinical brochure.
Topics: Animals; Antibiotics, Antineoplastic; Carbamates; Clinical Trials as Topic; Dogs; Female; Haplorhini | 1968 |
46 other studies available for carbamates and Neoplasms
| Article | Year |
|---|---|
Screening the biological properties of transition metal carbamates reveals gold(I) and silver(I) complexes as potent cytotoxic and antimicrobial agents.
Topics: A549 Cells; Anti-Infective Agents; Apoptosis; Carbamates; Cell Cycle Checkpoints; Coordination Compl | 2022 |
Benzimidazole-carbamate anthelmintics: Perspective candidates for the anticancer drug development.
Topics: Anthelmintics; Antineoplastic Agents; Benzimidazoles; Carbamates; Drug Development; Drug Repositioni | 2022 |
Design, synthesis and promising anti-tumor efficacy of novel imidazo[1,2-a]pyridine derivatives as potent autotaxin allosteric inhibitors.
Topics: Animals; Carbamates; Cell Line, Tumor; Dose-Response Relationship, Drug; Humans; Mice; Neoplasms; Ph | 2022 |
PEGylated Liposomes Loaded with Carbamate Inhibitor ANP0903 Trigger Apoptosis by Enhancing ER Stress in HepG2 Cancer Cells.
Topics: Antineoplastic Agents; Apoptosis; Carbamates; Cell Line, Tumor; Hep G2 Cells; Humans; Liposomes; Neo | 2023 |
Immobilized doxorubicin and ribociclib carbamate linkers encaged in surface modified cubosomes spatially target tumor reductive environment to enhance antitumor efficacy.
Topics: Carbamates; Doxorubicin; Drug Carriers; Glutathione; Gold; Humans; Metal Nanoparticles; Neoplasms | 2023 |
Inhibition of tumor propellant glutathione peroxidase 4 induces ferroptosis in cancer cells and enhances anticancer effect of cisplatin.
Topics: A549 Cells; Animals; Carbamates; Cell Movement; Cisplatin; Dipeptides; DNA Methylation; Epigenesis, | 2020 |
The fatty-acid amide hydrolase inhibitor URB597 inhibits MICA/B shedding.
Topics: Amidohydrolases; Benzamides; Carbamates; Cell Line, Tumor; Culture Media; Gene Expression Regulation | 2020 |
A sensitive and fast responsive fluorescent probe for imaging hypoxic tumors.
Topics: Animals; Carbamates; Cell Line, Tumor; Escherichia coli; Fluorescent Dyes; Humans; Hypoxia; Mice, In | 2018 |
Sofosbuvir-Based Therapy in Hepatitis C Virus-Infected Cancer Patients: A Prospective Observational Study.
Topics: Aged; Antiviral Agents; Benzimidazoles; Breast Neoplasms; Carbamates; Carcinoma, Hepatocellular; Dru | 2019 |
Hydrogels with prolonged release of therapeutic antibody: Block junction chemistry modification of 'ABA' copolymers provides superior anticancer efficacy.
Topics: Animals; Antineoplastic Agents, Immunological; Carbamates; Cell Line, Tumor; Delayed-Action Preparat | 2019 |
tert-Butylcarbamate-containing histone deacetylase inhibitors: apoptosis induction, cytodifferentiation, and antiproliferative activities in cancer cells.
Topics: Antineoplastic Agents; Apoptosis; Carbamates; Cell Differentiation; Cell Line, Tumor; Cell Prolifera | 2013 |
ZRX1, the first EGFR inhibitor-capecitabine based combi-molecule, requires carboxylesterase-mediated hydrolysis for optimal activity.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Carbam | 2013 |
Biscarbamate cross-linked low molecular weight Polyethylenimine polycation as an efficient intra-cellular delivery cargo for cancer therapy.
Topics: Animals; Carbamates; Cell Line; Cell Line, Tumor; Cross-Linking Reagents; Humans; Luciferases; Mice; | 2014 |
Clinico-morphological features of BRAF inhibition-induced proliferative skin lesions in cancer patients.
Topics: Adult; Aged; Benzimidazoles; Carbamates; Female; Humans; Imidazoles; Indoles; Male; Middle Aged; Neo | 2015 |
siRNA delivery into tumor cells by cationic cholesterol derivative-based nanoparticles and liposomes.
Topics: Animals; Carbamates; Cholesterol; Female; Humans; Liposomes; Luciferases, Firefly; MCF-7 Cells; Mice | 2015 |
The Methylene Alkoxy Carbamate Self-Immolative Unit: Utilization for the Targeted Delivery of Alcohol-Containing Payloads with Antibody-Drug Conjugates.
Topics: Aminobenzoates; Animals; Antineoplastic Agents, Immunological; Carbamates; Cell Line, Tumor; Drug De | 2016 |
Evaluation of the carcinogenicity of a series of esters of carbamic acid.
Topics: Carbamates; Esters; Humans; Neoplasms | 1947 |
Novel DNA-directed alkylating agents: design, synthesis and potent antitumor effect of phenyl N-mustard-9-anilinoacridine conjugates via a carbamate or carbonate linker.
Topics: Acridines; Animals; Antineoplastic Agents, Alkylating; Carbamates; Carbonates; Cell Line, Tumor; DNA | 2009 |
Synthesis and biological evaluation of a novel (99m)Tc nitrido radiopharmaceutical with deoxyglucose dithiocarbamate, showing tumor uptake.
Topics: Animals; Carbamates; Deoxyglucose; Isotope Labeling; Mice; Neoplasms; Organotechnetium Compounds; Ra | 2009 |
Preclinical efficacy of a carboxylesterase 2-activated prodrug of doxazolidine.
Topics: Animals; Antineoplastic Agents; Blotting, Western; Carbamates; Carboxylesterase; Cell Line, Tumor; C | 2009 |
Carbamate-linked lactose: design of clusters and evidence for selectivity to block binding of human lectins to (neo)glycoproteins with increasing degree of branching and to tumor cells.
Topics: Carbamates; Drug Design; Drug Evaluation, Preclinical; Glycoproteins; Humans; Lactose; Lectins; Neop | 2009 |
Novel microtubule-targeting agents, pyrrolo-1,5-benzoxazepines, induce apoptosis in multi-drug-resistant cancer cells.
Topics: Antineoplastic Agents; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Bindi | 2010 |
Iron complexation to oxygen rich marine natural products: a computational study.
Topics: Alkanes; Animals; Antineoplastic Agents; Biological Products; Carbamates; Cell Line, Tumor; Chemical | 2010 |
Synthesis and biological characterisation of novel dithiocarbamate containing 5-nitroimidazole (99m)Tc-complexes as potential agents for targeting hypoxia.
Topics: Animals; Carbamates; Cell Hypoxia; Metronidazole; Mice; Neoplasms; Nitroimidazoles; Organotechnetium | 2011 |
Total synthesis and biological evaluation of a series of macrocyclic hybrids and analogues of the antimitotic natural products dictyostatin, discodermolide, and taxol.
Topics: Alkanes; Antimitotic Agents; Antineoplastic Agents; Carbamates; Cell Line, Tumor; Drug Screening Ass | 2011 |
Synthesis and biodistribution of a new (99m) Tc-oxo complex with deoxyglucose dithiocarbamate for tumor imaging.
Topics: Animals; Carbamates; Cell Line, Tumor; Coordination Complexes; Deoxyglucose; Fluorodeoxyglucose F18; | 2012 |
The secretory proprotein convertases furin, PC5, and PC7 activate VEGF-C to induce tumorigenesis.
Topics: Amino Acid Motifs; Animals; Binding Sites; Blotting, Western; Carbamates; Cell Transformation, Neopl | 2003 |
[An antral polyp associated with a cancer of the greater currature].
Topics: Carbamates; Humans; Neoplasms; Organometallic Compounds; Paranasal Sinus Diseases; Polyps; Stomach N | 1952 |
Dual antagonists; alkyl N-(bis-(ethylenimido) phosphoro)-carbamates; a new series of anti-tumour agents.
Topics: Antineoplastic Agents; Carbamates; Esters; Humans; Neoplasms | 1959 |
INHIBITION OF TUMORIGENIC ACTION OF URETHANE BY BUTYL CARBAMATE.
Topics: Animals; Carbamates; Carcinogens; Mice; Neoplasms; Neoplasms, Experimental; Research; Skin Neoplasms | 1963 |
CATALASE ACTIVITY IN THE EPIDERMIS OF PATIENTS WITH ADVANCED CANCER.
Topics: Antineoplastic Agents; Breast Neoplasms; Carbamates; Catalase; Clinical Enzyme Tests; Cobalt Isotope | 1964 |
COMBINED USE OF AB-132 (METUREDEPA, TURLOC) AND X-IRRADIATION IN THE MANAGEMENT OF ADVANCED BRONCHOGENIC CARCINOMA.
Topics: Alkylating Agents; Antineoplastic Agents; Aziridines; Biomedical Research; Carbamates; Carcinoma, Br | 1964 |
OBSERVATIONS ON THE USE OF CANCER CHEMOTHERAPEUTIC AGENTS IN PATIENTS WITH MYCOSIS FUNGOIDES.
Topics: Alkylating Agents; Anti-Bacterial Agents; Antineoplastic Agents; Carbamates; Chlorambucil; Dactinomy | 1964 |
THE USE OF THE DRUGS AB 103 AND AB 132 IN THE COMBINED TREATMENT OF TUMOURS OF THE CERVICAL AND PULMONARY REGIONS.
Topics: Alkylating Agents; Antineoplastic Agents; Aziridines; Carbamates; Carcinoma, Bronchogenic; Carcinoma | 1964 |
UNUSUAL RADIOLOGICAL PRESENTATION OF AN ANTRAL POLYP.
Topics: Carbamates; Humans; Maxillary Sinus; Neoplasms; Organometallic Compounds; Paranasal Sinus Diseases; | 1965 |
Inhibition of sea-urchin egg cleavage by a series of substituted carbamates.
Topics: Carbamates; Neoplasms; Urethane | 1950 |
Risk/risk trade-offs in pesticide regulation: an exploratory analysis of the public health effects of a ban on organophosphate and carbamate pesticides.
Topics: Agriculture; Carbamates; Diet; Environmental Exposure; Food Contamination; Humans; Income; Insectici | 2000 |
[Results of the clinical study of a preparation of diiodobenzotef in malignant tumors].
Topics: Adult; Aged; Antineoplastic Agents; Aziridines; Azirines; Benzamides; Breast Neoplasms; Carbamates; | 1975 |
Initial clinical studies with copovithane.
Topics: Adult; Aged; Antineoplastic Agents; Carbamates; Cytotoxicity, Immunologic; Drug Evaluation; Drug Tol | 1986 |
Synthesis and antineoplastic activity of 5-aryl-2,3-dihydropyrrolo[2,1-b]thiazole-6,7-dimethanol 6,7-bis(isopropylcarbamates).
Topics: Carbamates; Cell Division; Cell Survival; Chemical Phenomena; Chemistry; Colonic Neoplasms; Humans; | 1988 |
Pharmacokinetics and tissue disposition of the biological response modifier BAY i 7433 (copovithane) in patients with cancer.
Topics: Antineoplastic Agents; Biopsy; Carbamates; Chromatography, High Pressure Liquid; Drug Evaluation; Hu | 1986 |
[Clinical studies on carbazilquinone in the treatment of malignant diseases].
Topics: Antineoplastic Agents; Azirines; Carbamates; Female; Humans; Male; Neoplasms; Quinones | 1973 |
Regional perfusion and circulation-stop method for chemotherapy of cancer and metastasis.
Topics: Animals; Antineoplastic Agents; Azirines; Carbamates; Chemotherapy, Cancer, Regional Perfusion; Chym | 1974 |
Skin homograft survival in cancer chemotherapy patients.
Topics: Adult; Aged; Antineoplastic Agents; Carbamates; Female; Fluorouracil; Humans; Immunosuppressive Agen | 1966 |
Is toxicity really necessary? I. The question.
Topics: Alkylating Agents; Carbamates; Chlorambucil; Fluorouracil; Humans; Leukocyte Count; Mercaptopurine; | 1966 |
Is toxicity really necessary? II. Source and analysis of data.
Topics: Alkylating Agents; Carbamates; Chlorambucil; Fluorouracil; Humans; Leukocyte Count; Leukopenia; Merc | 1966 |