carbamates has been researched along with Lewy Body Disease in 20 studies
Lewy Body Disease: A neurodegenerative disease characterized by dementia, mild parkinsonism, and fluctuations in attention and alertness. The neuropsychiatric manifestations tend to precede the onset of bradykinesia, MUSCLE RIGIDITY, and other extrapyramidal signs. DELUSIONS and visual HALLUCINATIONS are relatively frequent in this condition. Histologic examination reveals LEWY BODIES in the CEREBRAL CORTEX and BRAIN STEM. SENILE PLAQUES and other pathologic features characteristic of ALZHEIMER DISEASE may also be present. (From Neurology 1997;48:376-380; Neurology 1996;47:1113-1124)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The aim of this analysis of the effects of cholinergic therapy in dementia with Lewy bodies was to determine whether rivastigmine-induced benefits in attention and memory could be predicted by the presence of visual hallucinations." | 9.11 | Hallucinations predict attentional improvements with rivastigmine in dementia with lewy bodies. ( Ferrara, R; McKeith, IG; Perry, E; Wesnes, KA, 2004) |
| "The aim of this analysis of the effects of cholinergic therapy in dementia with Lewy bodies was to determine whether rivastigmine-induced benefits in attention and memory could be predicted by the presence of visual hallucinations." | 5.11 | Hallucinations predict attentional improvements with rivastigmine in dementia with lewy bodies. ( Ferrara, R; McKeith, IG; Perry, E; Wesnes, KA, 2004) |
| " Testing was conducted prior to dosing and then again at weeks 12, 20 and 23." | 2.70 | Effects of rivastigmine on cognitive function in dementia with lewy bodies: a randomised placebo-controlled international study using the cognitive drug research computerised assessment system. ( Anand, R; Cicin-Sain, A; Del Ser, T; Emre, M; Ferrara, R; McKeith, IG; Spano, PF; Spiegel, R; Wesnes, KA, 2002) |
| "Treatment with donepezil and rivastigmine (successively) did not produce the desired benefits." | 1.32 | A case study in the treatment of dementia with Lewy bodies. ( Kaufer, DI, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 19 (95.00) | 29.6817 |
| 2010's | 1 (5.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fujishiro, H | 1 |
| Scheepmaker, AJ | 1 |
| Horstink, MW | 1 |
| Hoefnagels, WH | 1 |
| Strijks, FE | 1 |
| Moerkens, RM | 1 |
| Dhondt, AD | 1 |
| Mol, JA | 1 |
| Wild, R | 1 |
| Pettit, T | 1 |
| Burns, A | 1 |
| Kaufer, DI | 2 |
| de Brito-Marques, PR | 1 |
| de Mello, RV | 1 |
| Montenegro, L | 1 |
| McKeith, IG | 5 |
| Wesnes, KA | 2 |
| Perry, E | 1 |
| Ferrara, R | 4 |
| Sagi, Y | 1 |
| Driguès, N | 1 |
| Youdim, MB | 1 |
| Grace, JB | 2 |
| Walker, Z | 2 |
| Byrne, EJ | 3 |
| Wilkinson, D | 2 |
| Stevens, T | 2 |
| Perry, EK | 1 |
| Walker, MP | 1 |
| Del Ser, T | 3 |
| McKeith, I | 2 |
| Anand, R | 3 |
| Cicin-Sain, A | 3 |
| Spiegel, R | 3 |
| Cummings, JL | 1 |
| Spano, P | 1 |
| Emre, M | 2 |
| Wesnes, K | 1 |
| Patterson, C | 1 |
| Hogan, DB | 1 |
| Grace, J | 1 |
| Daniel, S | 1 |
| Shankar, KK | 1 |
| Butler, S | 1 |
| Woolford, J | 1 |
| Waite, J | 1 |
| Maclean, LE | 1 |
| Collins, CC | 1 |
| Spano, PF | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| An Open Label 24-Week, Flexible Dose Trial to Assess the Safety and Efficacy of Galantamine in Patients With Dementia With Lewy Bodies[NCT00230997] | Phase 3 | 50 participants | Interventional | 2002-12-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for carbamates and Lewy Body Disease
| Article | Year |
|---|---|
Cholinesterase inhibitors for dementia with Lewy bodies.
Topics: Aged; Carbamates; Cholinesterase Inhibitors; Humans; Lewy Body Disease; Phenylcarbamates; Randomized | 2003 |
Brief review: rivastigmine, a second cholinesterase inhibitor.
Topics: Aged; Alzheimer Disease; Carbamates; Cholinesterase Inhibitors; Humans; Lewy Body Disease; Neuroprot | 2001 |
Understanding changes in cholinergic function: implications for treating dementia.
Topics: Activities of Daily Living; Alzheimer Disease; Carbamates; Cholinergic Fibers; Cholinesterase Inhibi | 2002 |
6 trials available for carbamates and Lewy Body Disease
| Article | Year |
|---|---|
Hallucinations predict attentional improvements with rivastigmine in dementia with lewy bodies.
Topics: Aged; Attention; Carbamates; Disease Progression; Double-Blind Method; Female; Hallucinations; Human | 2004 |
Rivastigmine in the treatment of dementia with Lewy bodies: preliminary findings from an open trial.
Topics: Aged; Aged, 80 and over; Carbamates; Cholinesterase Inhibitors; Cognition Disorders; Drug Tolerance; | 2000 |
Dementia with lewy bodies: findings from an international multicentre study.
Topics: Aged; Aged, 80 and over; Carbamates; Cholinesterase Inhibitors; Female; Humans; Lewy Body Disease; M | 2000 |
Efficacy of rivastigmine in dementia with Lewy bodies: a randomised, double-blind, placebo-controlled international study.
Topics: Aged; Carbamates; Cholinesterase Inhibitors; Double-Blind Method; Female; Humans; Lewy Body Disease; | 2000 |
Long-Term use of rivastigmine in patients with dementia with Lewy bodies: an open-label trial.
Topics: Aged; Aged, 80 and over; Carbamates; Cholinesterase Inhibitors; Cognition; Female; Humans; Lewy Body | 2001 |
Effects of rivastigmine on cognitive function in dementia with lewy bodies: a randomised placebo-controlled international study using the cognitive drug research computerised assessment system.
Topics: Aged; Carbamates; Diagnosis, Computer-Assisted; Double-Blind Method; Female; Follow-Up Studies; Huma | 2002 |
11 other studies available for carbamates and Lewy Body Disease
| Article | Year |
|---|---|
Effects of gabapentin enacarbil on restless legs syndrome and leg pain in dementia with Lewy bodies.
Topics: Aged; Carbamates; Dopamine Agonists; Female; gamma-Aminobutyric Acid; Hallucinations; Humans; Japan; | 2014 |
[Dementia with Lewy bodies; 2 patients with exacerbation due to an atypical antipsychotic, but with a favorable response to the cholinesterase inhibitor rivastigmine].
Topics: Aged; Aged, 80 and over; Antiparkinson Agents; Antipsychotic Agents; Benzodiazepines; Carbamates; Ch | 2003 |
[Dementia with Lewy bodies; 2 patients with exacerbation due to an atypical antipsychotic, but with a favorable response to the cholinesterase inhibitor rivastigmine].
Topics: Carbamates; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Humans; Lewy Body Disease; | 2003 |
[Dementia with Lewy bodies; 2 patients with exacerbation due to an atypical antipsychotic, but with a favorable response to the cholinesterase inhibitor rivastigmine].
Topics: Carbamates; Cholinesterase Inhibitors; Hospitalization; Humans; Lewy Body Disease; Neuroprotective A | 2003 |
Pharmacologic treatment expectations in the management of dementia with Lewy bodies.
Topics: Aged; Alzheimer Disease; Antipsychotic Agents; Brain; Carbamates; Cholinesterase Inhibitors; Diagnos | 2004 |
Nightmares without atonia as an early symptom of diffuse Lewy bodies disease.
Topics: Aged; Atrophy; Carbamates; Cholinesterase Inhibitors; Dreams; Fatal Outcome; Humans; Immunohistochem | 2003 |
A case study in the treatment of dementia with Lewy bodies.
Topics: Aged; Aged, 80 and over; Carbamates; Cognition Disorders; Donepezil; Drug Resistance; Female; Galant | 2004 |
The neurochemical and behavioral effects of the novel cholinesterase-monoamine oxidase inhibitor, ladostigil, in response to L-dopa and L-tryptophan, in rats.
Topics: Animals; Basal Ganglia; Behavior, Animal; Carbamates; Cholinesterase Inhibitors; Dopamine; Hippocamp | 2005 |
A comparison of sleep profiles in patients with dementia with lewy bodies and Alzheimer's disease.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Carbamates; Cholinesterase Inhibitors; Female; Humans; L | 2000 |
Cholinesterase inhibitors: expanding applications.
Topics: Alzheimer Disease; Carbamates; Cholinesterase Inhibitors; Humans; Lewy Body Disease; Phenylcarbamate | 2000 |
Dementia with Lewy bodies treated with rivastigmine: effects on cognition, neuropsychiatric symptoms, and sleep.
Topics: Aged; Aged, 80 and over; Carbamates; Cholinesterase Inhibitors; Cognition; Female; Humans; Lewy Body | 2001 |