carbamates has been researched along with Huntington Disease in 3 studies
Huntington Disease: A familial disorder inherited as an autosomal dominant trait and characterized by the onset of progressive CHOREA and DEMENTIA in the fourth or fifth decade of life. Common initial manifestations include paranoia; poor impulse control; DEPRESSION; HALLUCINATIONS; and DELUSIONS. Eventually intellectual impairment; loss of fine motor control; ATHETOSIS; and diffuse chorea involving axial and limb musculature develops, leading to a vegetative state within 10-15 years of disease onset. The juvenile variant has a more fulminant course including SEIZURES; ATAXIA; dementia; and chorea. (From Adams et al., Principles of Neurology, 6th ed, pp1060-4)
| Excerpt | Relevance | Reference |
|---|---|---|
| " In the R6/2 mouse HD model, induced DREAM haplodeficiency or blockade of DREAM activity by chronic administration of the drug repaglinide delayed onset of motor dysfunction, reduced striatal atrophy, and prolonged life span." | 1.43 | Activating transcription factor 6 derepression mediates neuroprotection in Huntington disease. ( Arrabal, MD; Casado-Vela, J; Cercós, P; De la Cruz, A; Dopazo, XM; González, P; González, T; Gutierrez-Rodriguez, M; Higueras, E; Li, JY; Mellström, B; Morón-Oset, J; Naranjo, JR; Oliveros, JC; Prieto, A; Rábano, A; Valenzuela, C; Villar, D; Zhang, H, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| López-Hurtado, A | 1 |
| Burgos, DF | 1 |
| González, P | 2 |
| Dopazo, XM | 2 |
| González, V | 1 |
| Rábano, A | 2 |
| Mellström, B | 2 |
| Naranjo, JR | 2 |
| Zhang, H | 1 |
| Villar, D | 1 |
| Morón-Oset, J | 1 |
| Higueras, E | 1 |
| Oliveros, JC | 1 |
| Arrabal, MD | 1 |
| Prieto, A | 1 |
| Cercós, P | 1 |
| González, T | 1 |
| De la Cruz, A | 1 |
| Casado-Vela, J | 1 |
| Valenzuela, C | 1 |
| Gutierrez-Rodriguez, M | 1 |
| Li, JY | 1 |
| Rot, U | 1 |
| Kobal, J | 1 |
| Sever, A | 1 |
| Pirtosek, Z | 1 |
| Mesec, A | 1 |
3 other studies available for carbamates and Huntington Disease
| Article | Year |
|---|---|
Inhibition of DREAM-ATF6 interaction delays onset of cognition deficit in a mouse model of Huntington's disease.
Topics: Activating Transcription Factor 6; Animals; Carbamates; Cognition Disorders; Disease Models, Animal; | 2018 |
Activating transcription factor 6 derepression mediates neuroprotection in Huntington disease.
Topics: Activating Transcription Factor 6; Animals; Carbamates; CHO Cells; Corpus Striatum; Cricetulus; Dise | 2016 |
Rivastigmine in the treatment of Huntington's disease.
Topics: Carbamates; Cholinesterase Inhibitors; Humans; Huntington Disease; Phenylcarbamates; Rivastigmine | 2002 |