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carbamates and Graft vs Host Disease

carbamates has been researched along with Graft vs Host Disease in 11 studies

Graft vs Host Disease: The clinical entity characterized by anorexia, diarrhea, loss of hair, leukopenia, thrombocytopenia, growth retardation, and eventual death brought about by the GRAFT VS HOST REACTION.

Research Excerpts

ExcerptRelevanceReference
"LF 08-0299 (Tresperimus), a novel immunosuppressive compound, has been previously shown to prevent graft-versus-host disease in murine models."3.70T cell repertoire expression in murine recipients of bone marrow transplant after LF 08-0299 (Tresperimus) administration. ( Annat, J; Dutartre, P, 1998)
"Tresperimus is a novel agent that induces allogeneic transplant tolerance."2.41Tresperimus: a new agent for transplant tolerance induction. ( Simpson, D, 2001)
"Tresperimus (LF-08-0299) is an immunosuppressant under development by Laboratoires Fournier for its potential use in organ transplant rejection."1.31Tresperimus (Laboratoires Fournier). ( Elices, MJ, 2001)
" A short term LF 08--0299 treatment at optimal dosage protected more than 75% of recipient mice from lethal GVHD induced either across minor antigens alone or the full H2 barrier."1.29Prevention of lethal graft-versus-host disease following allogeneic bone marrow transplantation in mice by short course administration of LF 08-0299. ( Annat, J; Bruley-Rosset, M; Churaqui, E; Dutartre, P, 1996)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's7 (63.64)18.2507
2000's4 (36.36)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bruley-Rosset, M3
Churaqui, E3
Annat, J5
Dutartre, P6
Komesli, S1
Dumas, C1
Lebreton, L1
Jost, E1
Carboni, B1
Vaultier, M1
Renaut, P1
Decker, CJ1
Heiser, AD1
Chaturvedi, PR1
Faust, TJ1
Ku, G1
Moseley, S1
Nimmesgern, E1
Elices, MJ1
Simpson, D1
Jacobsohn, DA1
Vogelsang, GB1

Reviews

2 reviews available for carbamates and Graft vs Host Disease

ArticleYear
Tresperimus: a new agent for transplant tolerance induction.
    Expert opinion on investigational drugs, 2001, Volume: 10, Issue:7

    Topics: Animals; Carbamates; Graft vs Host Disease; Half-Life; Humans; Immunosuppressive Agents; Maximum Tol

2001
Novel pharmacotherapeutic approaches to prevention and treatment of GVHD.
    Drugs, 2002, Volume: 62, Issue:6

    Topics: Acute Disease; Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Carbamates; Chron

2002

Other Studies

9 other studies available for carbamates and Graft vs Host Disease

ArticleYear
LF 08-0299 protects murine recipients of minor antigen disparate donor marrow from lethal graft-versus-host disease.
    Annals of the New York Academy of Sciences, 1995, Dec-29, Volume: 770

    Topics: Animals; Bone Marrow Transplantation; Carbamates; Graft vs Host Disease; Immune Tolerance; Immunosup

1995
Prevention of lethal graft-versus-host disease following allogeneic bone marrow transplantation in mice by short course administration of LF 08-0299.
    Transplantation, 1996, Sep-27, Volume: 62, Issue:6

    Topics: Adoptive Transfer; Animals; Bone Marrow Transplantation; Carbamates; Drug Administration Schedule; D

1996
LF 08-0299 protects murine recipients of minor antigen disparate donor bone marrow from lethal graft-versus-host disease.
    Transplantation proceedings, 1996, Volume: 28, Issue:6

    Topics: Animals; Bone Marrow Transplantation; Carbamates; Graft Survival; Graft vs Host Disease; Histocompat

1996
T cell repertoire expression in murine recipients of bone marrow transplant after LF 08-0299 (Tresperimus) administration.
    Transplant immunology, 1998, Volume: 6, Issue:4

    Topics: Animals; Bone Marrow Transplantation; Carbamates; Cell Differentiation; Graft vs Host Disease; Immun

1998
Analysis of in vivo immunosuppressive and in vitro interaction with constitutive heat shock protein 70 activity of LF08-0299 (Tresperimus) and analogues.
    International journal of immunopharmacology, 1999, Volume: 21, Issue:5

    Topics: Animals; Binding Sites; Carbamates; Chromatography, Affinity; Graft vs Host Disease; HSP70 Heat-Shoc

1999
Tresperimus. LF 080299.
    Drugs in R&D, 1999, Volume: 1, Issue:1

    Topics: Animals; Carbamates; Drugs, Investigational; Graft Rejection; Graft vs Host Disease; Humans; Immunos

1999
Structure-immunosuppressive activity relationships of new analogues of 15-deoxyspergualin. 2. Structural modifications of the spermidine moiety.
    Journal of medicinal chemistry, 1999, Nov-18, Volume: 42, Issue:23

    Topics: Animals; Carbamates; Drug Evaluation, Preclinical; Graft vs Host Disease; Guanidines; Heart Transpla

1999
The novel IMPDH inhibitor VX-497 prolongs skin graft survival and improves graft versus host disease in mice.
    Drugs under experimental and clinical research, 2001, Volume: 27, Issue:3

    Topics: Animals; Carbamates; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Inhibitors; Enzyme-Li

2001
Tresperimus (Laboratoires Fournier).
    Current opinion in investigational drugs (London, England : 2000), 2001, Volume: 2, Issue:3

    Topics: Animals; Carbamates; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Drug Eva

2001