Page last updated: 2024-10-16

carbamates and Fibrosis

carbamates has been researched along with Fibrosis in 12 studies

Fibrosis: Any pathological condition where fibrous connective tissue invades any organ, usually as a consequence of inflammation or other injury.

Research Excerpts

ExcerptRelevanceReference
" Accordingly, we evaluated the efficacy of 8 weeks fixed-dose combination of grazoprevir-elbasvir in treatment-naïve patients, with non-severe fibrosis."9.34Phase 3, Multicenter Open-Label study to investigate the efficacy of elbasvir and grazoprevir fixed-dose combination for 8 weeks in treatment-naïve, HCV GT1b-infected patients, with non-severe fibrosis. ( Abergel, A; Andant, N; Asselah, T; Bailly, F; Buchard, B; Chanteranne, B; Di Martino, V; Dodel, M; Faure, F; Fouchard-Hubert, I; Gournay, J; Lamblin, G; Larrey, D; Loustaud-Ratti, V; Mallat, A; Muti, L; Pereira, B; Pol, S; Reymond, M; Samuel, D; Teilhet, C; Tran, A, 2020)
" Accordingly, we evaluated the efficacy of 8 weeks fixed-dose combination of grazoprevir-elbasvir in treatment-naïve patients, with non-severe fibrosis."5.34Phase 3, Multicenter Open-Label study to investigate the efficacy of elbasvir and grazoprevir fixed-dose combination for 8 weeks in treatment-naïve, HCV GT1b-infected patients, with non-severe fibrosis. ( Abergel, A; Andant, N; Asselah, T; Bailly, F; Buchard, B; Chanteranne, B; Di Martino, V; Dodel, M; Faure, F; Fouchard-Hubert, I; Gournay, J; Lamblin, G; Larrey, D; Loustaud-Ratti, V; Mallat, A; Muti, L; Pereira, B; Pol, S; Reymond, M; Samuel, D; Teilhet, C; Tran, A, 2020)
"Using data from a phase III clinical trial (GIFT-I) that enrolled Japanese patients with HCV genotype 1b infection, population pharmacokinetic models were developed for the drugs that comprise the 2D regimen: paritaprevir, ombitasvir, and ritonavir."2.84Population Pharmacokinetics of Paritaprevir, Ombitasvir, and Ritonavir in Japanese Patients with Hepatitis C Virus Genotype 1b Infection. ( Gopalakrishnan, SM; Khatri, A; Menon, RM; Mensing, S; Polepally, AR, 2017)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's8 (66.67)24.3611
2020's4 (33.33)2.80

Authors

AuthorsStudies
Lei, H2
Li, Z1
Li, T2
Wu, H1
Yang, J2
Yang, X2
Yang, Y2
Jiang, N1
Zhai, X2
Cao, Z1
Liu, Z1
Sun, R1
Mashaal, AR1
Abd El-Hameed, M1
El Ray, AA1
Mahmoud Diab, T1
Dawood, RM1
Shemis, MA1
Seyam, M1
Kim, JW1
Abergel, A1
Asselah, T1
Mallat, A1
Chanteranne, B1
Faure, F1
Larrey, D1
Gournay, J1
Loustaud-Ratti, V1
Di Martino, V1
Fouchard-Hubert, I1
Pol, S1
Bailly, F1
Samuel, D1
Tran, A1
Dodel, M1
Andant, N1
Lamblin, G1
Muti, L1
Reymond, M1
Teilhet, C1
Pereira, B1
Buchard, B1
Milan, M1
Pace, V1
Maiullari, F1
Chirivì, M1
Baci, D1
Maiullari, S1
Madaro, L1
Maccari, S1
Stati, T1
Marano, G1
Frati, G1
Puri, PL2
De Falco, E1
Bearzi, C1
Rizzi, R1
Consalvi, S1
Mozzetta, C1
Bettica, P1
Germani, M1
Fiorentini, F1
Del Bene, F1
Rocchetti, M1
Leoni, F1
Monzani, V1
Mascagni, P1
Saccone, V1
Beinhardt, S1
Peck-Radosavljevic, M1
Hofer, H1
Ferenci, P1
Saab, S1
Parisé, H1
Virabhak, S1
Wang, A1
Marx, SE1
Sanchez Gonzalez, Y1
Misurski, D1
Johnson, S1
Gopalakrishnan, SM1
Polepally, AR1
Mensing, S1
Khatri, A1
Menon, RM1
Gross, ML1
Piecha, G1
Bierhaus, A1
Hanke, W1
Henle, T1
Schirmacher, P1
Ritz, E1
Wang, J1
Kulkarni, A1
Chintala, M1
Fink, LM1
Hauer-Jensen, M1

Reviews

1 review available for carbamates and Fibrosis

ArticleYear
Interferon-free antiviral treatment of chronic hepatitis C in the transplant setting.
    Transplant international : official journal of the European Society for Organ Transplantation, 2015, Volume: 28, Issue:9

    Topics: 2-Naphthylamine; Anilides; Antiviral Agents; Carbamates; Cholestasis, Intrahepatic; Clinical Trials

2015

Trials

2 trials available for carbamates and Fibrosis

ArticleYear
Phase 3, Multicenter Open-Label study to investigate the efficacy of elbasvir and grazoprevir fixed-dose combination for 8 weeks in treatment-naïve, HCV GT1b-infected patients, with non-severe fibrosis.
    Liver international : official journal of the International Association for the Study of the Liver, 2020, Volume: 40, Issue:8

    Topics: Adult; Aged; Amides; Antiviral Agents; Asia; Benzofurans; Carbamates; Cyclopropanes; Drug Therapy, C

2020
Population Pharmacokinetics of Paritaprevir, Ombitasvir, and Ritonavir in Japanese Patients with Hepatitis C Virus Genotype 1b Infection.
    Clinical pharmacokinetics, 2017, Volume: 56, Issue:1

    Topics: Adolescent; Adult; Aged; Anilides; Antiviral Agents; Carbamates; Cyclopropanes; Double-Blind Method;

2017

Other Studies

9 other studies available for carbamates and Fibrosis

ArticleYear
Novel imidazo[1,2-a]pyridine derivatives as potent ATX allosteric inhibitors: Design, synthesis and promising in vivo anti-fibrotic efficacy in mice lung model.
    Bioorganic chemistry, 2022, Volume: 120

    Topics: Animals; Carbamates; Disease Models, Animal; Fibrosis; Lung; Mice; Phosphoric Diester Hydrolases; Pi

2022
Hybrid imidazo[1,2-a]pyridine analogs as potent ATX inhibitors with concrete in vivo antifibrosis effect.
    Archiv der Pharmazie, 2022, Volume: 355, Issue:10

    Topics: Bleomycin; Carbamates; Fibrosis; Humans; Phosphoric Diester Hydrolases; Pyridines; Structure-Activit

2022
Detection of Occult Hepatitis C Virus Infection in Egyptian Patients Who Achieved a Sustained Virologic Response to Direct-Acting Antiviral Agents.
    Asian Pacific journal of cancer prevention : APJCP, 2022, Sep-01, Volume: 23, Issue:9

    Topics: Aged; alpha-Fetoproteins; Antiviral Agents; Carbamates; Cross-Sectional Studies; Drug Therapy, Combi

2022
What is the Long-term Benefit of Direct-acting Antiviral Therapy in Chronic Hepatitis C?
    Journal of Korean medical science, 2019, 10-28, Volume: 34, Issue:41

    Topics: Antiviral Agents; Carbamates; Fibrosis; Genotype; Hepacivirus; Hepatitis C, Chronic; Humans; Imidazo

2019
Givinostat reduces adverse cardiac remodeling through regulating fibroblasts activation.
    Cell death & disease, 2018, 01-25, Volume: 9, Issue:2

    Topics: Animals; Apoptosis; Carbamates; Endothelium; Epithelium; Female; Fibroblasts; Fibrosis; Gene Express

2018
Preclinical studies in the mdx mouse model of duchenne muscular dystrophy with the histone deacetylase inhibitor givinostat.
    Molecular medicine (Cambridge, Mass.), 2013, May-20, Volume: 19

    Topics: Animals; Carbamates; Cells, Cultured; Exercise Test; Fibrosis; Histone Deacetylase Inhibitors; Human

2013
Cost-effectiveness of currently recommended direct-acting antiviral treatments in patients infected with genotypes 1 or 4 hepatitis C virus in the US.
    Journal of medical economics, 2016, Volume: 19, Issue:8

    Topics: 2-Naphthylamine; Adult; Aged; Aged, 80 and over; Anilides; Antiviral Agents; Benzimidazoles; Carbama

2016
Glycated and carbamylated albumin are more "nephrotoxic" than unmodified albumin in the amphibian kidney.
    American journal of physiology. Renal physiology, 2011, Volume: 301, Issue:3

    Topics: Albumins; Ambystoma mexicanum; Animals; Carbamates; Fibrosis; Glycated Serum Albumin; Glycation End

2011
Inhibition of protease-activated receptor 1 ameliorates intestinal radiation mucositis in a preclinical rat model.
    International journal of radiation oncology, biology, physics, 2013, Jan-01, Volume: 85, Issue:1

    Topics: Animals; Benzofurans; Carbamates; Fibrosis; Intestinal Mucosa; Intestine, Small; Male; Mucositis; Pe

2013