Page last updated: 2024-10-16

carbamates and Cystic Fibrosis

carbamates has been researched along with Cystic Fibrosis in 9 studies

Cystic Fibrosis: An autosomal recessive genetic disease of the EXOCRINE GLANDS. It is caused by mutations in the gene encoding the CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR expressed in several organs including the LUNG, the PANCREAS, the BILIARY SYSTEM, and the SWEAT GLANDS. Cystic fibrosis is characterized by epithelial secretory dysfunction associated with ductal obstruction resulting in AIRWAY OBSTRUCTION; chronic RESPIRATORY INFECTIONS; PANCREATIC INSUFFICIENCY; maldigestion; salt depletion; and HEAT PROSTRATION.

Research Excerpts

ExcerptRelevanceReference
"Insulin and glucose levels in response to premeal insulin lispro or repaglinide were evaluated in adult patients with cystic fibrosis-related diabetes (CFRD) without fasting hyperglycemia."7.71Insulin and glucose excursion following premeal insulin lispro or repaglinide in cystic fibrosis-related diabetes. ( Milla, C; Moran, A; Phillips, J, 2001)
" Four trials (200 participants) are included: one short-term single-center trial (n = 7) comparing insulin with oral repaglinide and no medication in people with cystic fibrosis-related diabetes and normal fasting glucose; one long-term multicenter trial (n = 100, 74 of whom had cystic fibrosis-related diabetes) comparing insulin with oral repaglinide and placebo; one long-term multicenter trial (n = 73) comparing insulin with oral repaglinide; and one 12-week single-center trial (n = 20) comparing the long-acting insulin glargine to short-term neutral protamine Hagedorn insulin."4.93Insulin and oral agents for managing cystic fibrosis-related diabetes. ( Onady, GM; Stolfi, A, 2016)
"Insulin and glucose levels in response to premeal insulin lispro or repaglinide were evaluated in adult patients with cystic fibrosis-related diabetes (CFRD) without fasting hyperglycemia."3.71Insulin and glucose excursion following premeal insulin lispro or repaglinide in cystic fibrosis-related diabetes. ( Milla, C; Moran, A; Phillips, J, 2001)
" In another study using the same dosage regimen, amelubant appeared to be safe and well tolerated."2.43Leukotriene receptor antagonists in children with cystic fibrosis lung disease : anti-inflammatory and clinical effects. ( Schmitt-Grohé, S; Zielen, S, 2005)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (22.22)29.6817
2010's6 (66.67)24.3611
2020's1 (11.11)2.80

Authors

AuthorsStudies
Onady, GM2
Stolfi, A2
Giacomini, D1
Martelli, G1
Piccichè, M1
Calaresu, E1
Cocuzza, CE1
Musumeci, R1
Ballmann, M2
Hubert, D2
Assael, BM2
Staab, D1
Hebestreit, A1
Naehrlich, L1
Nickolay, T1
Prinz, N1
Holl, RW2
Döring, G2
Bragonzi, A1
Paroni, M1
Aktürk, FF1
Cigana, C1
Schmidt, A1
Gilpin, D1
Heyder, S1
Born, T1
Smaczny, C1
Kohlhäufl, M1
Wagner, TO1
Loebinger, MR1
Bilton, D1
Tunney, MM1
Elborn, JS1
Pier, GB1
Konstan, MW2
Ulrich, M1
Heltshe, SL1
Lands, LC1
Hilliard, KA1
Koker, P1
Bhattacharya, S1
Staab, A1
Hamilton, A1
Kronfeld, K1
Honer, M1
Schmitt-Grohé, S1
Zielen, S1
Moran, A1
Phillips, J1
Milla, C1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Open Randomised Prospective Comparative Multi-centre Intervention Study of Patients With Cystic Fibrosis and Early Diagnosed Diabetes Mellitus[NCT00662714]Phase 373 participants (Actual)Interventional2001-09-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

3 reviews available for carbamates and Cystic Fibrosis

ArticleYear
Drug treatments for managing cystic fibrosis-related diabetes.
    The Cochrane database of systematic reviews, 2020, 10-19, Volume: 10

    Topics: Administration, Oral; Bias; Blood Glucose; Carbamates; Cystic Fibrosis; Diabetes Mellitus; Fasting;

2020
Insulin and oral agents for managing cystic fibrosis-related diabetes.
    The Cochrane database of systematic reviews, 2016, Apr-18, Volume: 4

    Topics: Administration, Oral; Carbamates; Cystic Fibrosis; Diabetes Mellitus; Humans; Hyperglycemia; Hypogly

2016
Leukotriene receptor antagonists in children with cystic fibrosis lung disease : anti-inflammatory and clinical effects.
    Paediatric drugs, 2005, Volume: 7, Issue:6

    Topics: Adolescent; Amidines; Asthma; Bronchial Hyperreactivity; Carbamates; Child; Child, Preschool; Clinic

2005

Trials

3 trials available for carbamates and Cystic Fibrosis

ArticleYear
Repaglinide versus insulin for newly diagnosed diabetes in patients with cystic fibrosis: a multicentre, open-label, randomised trial.
    The lancet. Diabetes & endocrinology, 2018, Volume: 6, Issue:2

    Topics: Adolescent; Adult; Biomarkers; Blood Glucose; Carbamates; Child; Cystic Fibrosis; Diabetes Mellitus,

2018
A randomized double blind, placebo controlled phase 2 trial of BIIL 284 BS (an LTB4 receptor antagonist) for the treatment of lung disease in children and adults with cystic fibrosis.
    Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, 2014, Volume: 13, Issue:2

    Topics: Adolescent; Adult; Amidines; Anti-Inflammatory Agents; Bronchoalveolar Lavage Fluid; Carbamates; Chi

2014
Open randomised prospective comparative multi-centre intervention study of patients with cystic fibrosis and early diagnosed diabetes mellitus.
    BMC pediatrics, 2014, Mar-11, Volume: 14

    Topics: Adolescent; Algorithms; Carbamates; Child; Cystic Fibrosis; Diabetes Mellitus; Early Diagnosis; Huma

2014

Other Studies

3 other studies available for carbamates and Cystic Fibrosis

ArticleYear
Design and Synthesis of 4-Alkylidene-β-lactams: Benzyl- and Phenethyl-carbamates as Key Fragments to Switch on Antibacterial Activity.
    ChemMedChem, 2017, 09-21, Volume: 12, Issue:18

    Topics: Anti-Bacterial Agents; beta-Lactams; Carbamates; Cystic Fibrosis; Drug Design; Gram-Negative Bacteri

2017
BIIL 284 reduces neutrophil numbers but increases P. aeruginosa bacteremia and inflammation in mouse lungs.
    Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, 2014, Volume: 13, Issue:2

    Topics: Adult; Amidines; Animals; Anti-Inflammatory Agents; Bacteremia; Carbamates; Cystic Fibrosis; Disease

2014
Insulin and glucose excursion following premeal insulin lispro or repaglinide in cystic fibrosis-related diabetes.
    Diabetes care, 2001, Volume: 24, Issue:10

    Topics: Adult; Blood Glucose; Carbamates; Cystic Fibrosis; Diabetes Mellitus; Female; Food; Humans; Hypoglyc

2001