carbamates has been researched along with Constipation in 4 studies
Constipation: Infrequent or difficult evacuation of FECES. These symptoms are associated with a variety of causes, including low DIETARY FIBER intake, emotional or nervous disturbances, systemic and structural disorders, drug-induced aggravation, and infections.
| Excerpt | Relevance | Reference |
|---|---|---|
| " To examine the potential for drug-drug interactions at these two transporters, the pharmacokinetics of gabapentin enacarbil were evaluated in healthy adults after administration alone or in combination with either naproxen (an MCT-1 substrate) or cimetidine (an OCT2 substrate)." | 1.36 | Clinical pharmacokinetic drug interaction studies of gabapentin enacarbil, a novel transported prodrug of gabapentin, with naproxen and cimetidine. ( Blumenthal, R; Cundy, KC; Ho, J; Lal, R; Luo, W; Sukbuntherng, J; Vicente, V, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Shin, A | 1 |
| Acosta, A | 1 |
| Camilleri, M | 1 |
| Boldingh, A | 1 |
| Burton, D | 1 |
| Ryks, M | 1 |
| Rhoten, D | 1 |
| Zinsmeister, AR | 1 |
| Lal, R | 1 |
| Sukbuntherng, J | 1 |
| Luo, W | 1 |
| Vicente, V | 1 |
| Blumenthal, R | 1 |
| Ho, J | 1 |
| Cundy, KC | 1 |
| Jepps, TA | 1 |
| Olesen, SP | 1 |
| Greenwood, IA | 1 |
| Hussar, DA | 1 |
| Martinez, LN | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Phase II, Single-Center, Randomized, Parallel Group, Multiple Administration, Double-Blind, Placebo-Controlled Study to Evaluate the Pharmacodynamics of YKP10811 in Patients With Chronic or Functional Constipation[NCT01523184] | Phase 2 | 57 participants (Actual) | Interventional | 2012-03-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for carbamates and Constipation
| Article | Year |
|---|---|
One man's side effect is another man's therapeutic opportunity: targeting Kv7 channels in smooth muscle disorders.
Topics: Animals; Anticonvulsants; Carbamates; Constipation; Female; Humans; Hypertension; KCNQ1 Potassium Ch | 2013 |
1 trial available for carbamates and Constipation
| Article | Year |
|---|---|
A randomized trial of 5-hydroxytryptamine4-receptor agonist, YKP10811, on colonic transit and bowel function in functional constipation.
Topics: Adolescent; Adult; Aged; Benzamides; Carbamates; Colon; Constipation; Double-Blind Method; Female; G | 2015 |
2 other studies available for carbamates and Constipation
| Article | Year |
|---|---|
Clinical pharmacokinetic drug interaction studies of gabapentin enacarbil, a novel transported prodrug of gabapentin, with naproxen and cimetidine.
Topics: Adolescent; Adult; Biological Transport; Carbamates; Cimetidine; Constipation; Dose-Response Relatio | 2010 |
Elvitegravir/cobicistat, mirabegron, and linaclotide.
Topics: Acetanilides; Adenine; Anti-Retroviral Agents; Carbamates; Constipation; Deoxycytidine; Drug Combina | 2012 |