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carbamates and Cancer of Prostate

carbamates has been researched along with Cancer of Prostate in 41 studies

Research Excerpts

ExcerptRelevanceReference
"Importantly, prostate cancer-derived SPOP mutants failed to interact with Cdc20 to promote its degradation."1.46Prostate cancer-associated mutation in SPOP impairs its ability to target Cdc20 for poly-ubiquitination and degradation. ( Dai, X; Ding, Q; Gan, W; Li, M; Mitsiades, N; Wan, L; Wei, W; Wu, F; Zhang, J, 2017)
"Castration-resistant prostate cancer (CRPC) is still dependent on androgen receptor (AR) signaling."1.37Biological properties of androgen receptor pure antagonist for treatment of castration-resistant prostate cancer: optimization from lead compound to CH5137291. ( Arai, S; Ishikura, N; Kawata, H; Nakagawa, T; Nakamura, R; Nishimoto, A; Sato, H; Shiraishi, T; Tachibana, K; Yoshino, H, 2011)
"Transfection of miR-17* into prostate cancer PC-3 cells significantly reduces levels of the three antioxidant proteins and activity of the luciferase reporter under the control of miR-17* binding sequences located in the 3'-untranslated regions of the three target genes."1.36miR-17* suppresses tumorigenicity of prostate cancer by inhibiting mitochondrial antioxidant enzymes. ( Fang, F; Josson, S; St Clair, DK; St Clair, WH; Xu, Y; Zhang, J, 2010)
"Iejimalide B, has a dose and time dependent effect on cell number (as measured by crystal violet assay) in both cell lines."1.35Effects of Iejimalide B, a marine macrolide, on growth and apoptosis in prostate cancer cell lines. ( Helquist, P; Jeffrey, R; McHenry, P; Schweitzer, D; Tenniswood, M; Wang, WL, 2008)
"Carbamates 4 and 5 were 2."1.35Latrunculin A and its C-17-O-carbamates inhibit prostate tumor cell invasion and HIF-1 activation in breast tumor cells. ( Awate, B; Khanfar, MA; Liu, Y; Muralidharan, A; Nagle, DG; Sayed, KA; Shah, G; Shallal, HM; Youssef, DT; Zhou, YD, 2008)
"Prostate cancer bone metastases are characterized by their ability to induce osteoblastic lesions and local bone formation."1.32Notch signaling and ERK activation are important for the osteomimetic properties of prostate cancer bone metastatic cell lines. ( Abdulkadir, SA; McDonald, JM; Zayzafoon, M, 2004)

Research

Studies (41)

TimeframeStudies, this research(%)All Research%
pre-199016 (39.02)18.7374
1990's0 (0.00)18.2507
2000's9 (21.95)29.6817
2010's14 (34.15)24.3611
2020's2 (4.88)2.80

Authors

AuthorsStudies
Panda, PK1
Patra, S1
Naik, PP1
Praharaj, PP1
Mukhopadhyay, S1
Meher, BR1
Gupta, PK1
Verma, RS1
Maiti, TK1
Bhutia, SK1
Huxley, C1
Wibowo, M1
Lum, KY1
Gordon, S1
D'Hyon, S1
Guan, H1
Wang, X1
Chen, Y1
Si, M1
Wang, M1
White, JM1
Wahi, K1
Wang, Q2
Holst, J1
Davis, RA1
Noey, EL1
Yang, Z1
Li, Y1
Yu, H1
Richey, RN1
Merritt, JM1
Kjell, DP1
Houk, KN1
Bakthavatsalam, S1
Sleeper, ML1
Dharani, A1
George, DJ1
Zhang, T1
Franz, KJ1
Shi, J1
Chen, J1
Serradji, N1
Xu, X1
Zhou, H1
Ma, Y1
Sun, Z1
Jiang, P1
Du, Y1
Yang, J1
Dong, C1
Schmidt, A2
Meissner, RS1
Gentile, MA2
Chisamore, MJ2
Opas, EE1
Scafonas, A1
Cusick, TE1
Gambone, C2
Pennypacker, B1
Hodor, P1
Perkins, JJ1
Bai, C1
Ferraro, D1
Bettoun, DJ1
Wilkinson, HA1
Alves, SE2
Flores, O2
Ray, WJ1
Djigoué, GB1
Kenmogne, LC1
Roy, J1
Maltais, R1
Poirier, D1
Dillon, GM1
Baran, M1
Riley, S1
Wilkinson, H1
Wu, F1
Dai, X1
Gan, W1
Wan, L1
Li, M1
Mitsiades, N1
Wei, W1
Ding, Q1
Zhang, J2
Gediya, LK1
Khandelwal, A1
Patel, J1
Belosay, A1
Sabnis, G1
Mehta, J1
Purushottamachar, P1
Njar, VC2
Moreira, VM1
Vasaitis, TS1
Guo, Z1
Salvador, JA1
Floryk, D1
Thompson, TC1
Wang, WL1
McHenry, P1
Jeffrey, R1
Schweitzer, D1
Helquist, P1
Tenniswood, M1
Garofalo, A1
Goossens, L1
Lemoine, A1
Farce, A1
Arlot, Y1
Depreux, P1
Byun, HS1
Bittman, R1
Samadder, P1
Arthur, G1
Xu, Y1
Fang, F1
Josson, S1
St Clair, WH1
St Clair, DK1
Kawata, H1
Arai, S1
Nakagawa, T1
Ishikura, N1
Nishimoto, A1
Yoshino, H1
Shiraishi, T1
Tachibana, K1
Nakamura, R1
Sato, H1
Chang, JW1
Nomura, DK1
Cravatt, BF1
Gagnepain, J1
Moulin, E1
Nevado, C1
Waser, M1
Maier, A1
Kelter, G1
Fiebig, HH1
Fürstner, A1
Andrieu, T1
Bertolini, R1
Nichols, SE1
Setoud, R1
Frey, FJ1
Baker, ME1
Frey, BM1
Zayzafoon, M1
Abdulkadir, SA1
McDonald, JM1
Libertini, SJ1
Tepper, CG1
Rodriguez, V1
Asmuth, DM1
Kung, HJ1
Mudryj, M1
Plano, D1
Sanmartín, C1
Moreno, E1
Prior, C1
Calvo, A1
Palop, JA1
Sayed, KA1
Khanfar, MA1
Shallal, HM1
Muralidharan, A1
Awate, B1
Youssef, DT1
Liu, Y1
Zhou, YD1
Nagle, DG1
Shah, G1
Ryan, CW1
Shulman, KL1
Richards, JM1
Kugler, JW1
Sosman, JA1
Ansari, RH1
Vokes, EE1
Vogelzang, NJ1
Kadohama, N1
Kirdani, RY1
Murphy, GP5
Sandberg, AA1
Mayer, EJ1
Klein, D1
Welvaart, K1
Merrin, CE1
Mittelman, A3
Tritsch, GL1
Shukla, SK2
Erichsen, HG1
Nygaard, E1
de Leval, J1
Petit, R1
Bouffioux, C1
Szendröi, Z2
Könyves, I1
Szendi, L1
Eckhardt, S2
Hartay, F1
Zimel, H1
Bocancea, D1
Kocsár, L1
Karika, Z1
Füzi, M1
Tarján, G1
Reischel, G1
Müntzing, J2
Chu, TM1
Nilsson, T1
Polacek, J1
Lindberg, B1
Anderes, A1
Arquint, A1
Camponovo, F1
Deppeler, O1
Doerig, R1
Heim, H1
Humbert-Droz, P1
Jung, HP1
Magaro, L1
Sasso, M1
Vischer, C1
Wanner, J1
Wegmann, HJ1
Ziegler, E1
Jönsson, G1

Trials

2 trials available for carbamates and Cancer of Prostate

ArticleYear
CI-980 in advanced melanoma and hormone refractory prostate cancer.
    Investigational new drugs, 2000, Volume: 18, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Carbamates; Drug Resistance, Neoplasm; Female

2000
Treatment of prostatic carcinoma with Stilbostat.
    Neoplasma, 1974, Volume: 21, Issue:1

    Topics: Aged; Carbamates; Clinical Trials as Topic; Diethylstilbestrol; Drug Evaluation; Humans; Injections,

1974

Other Studies

39 other studies available for carbamates and Cancer of Prostate

ArticleYear
Deacetylation of LAMP1 drives lipophagy-dependent generation of free fatty acids by Abrus agglutinin to promote senescence in prostate cancer.
    Journal of cellular physiology, 2020, Volume: 235, Issue:3

    Topics: Adenine; Apoptosis; Autophagy; Benzamides; Carbamates; Cell Line, Tumor; Cell Proliferation; Cellula

2020
Synthesis of bilocularin A carbamate derivatives and their evaluation as leucine transport inhibitors in prostate cancer cells.
    Phytochemistry, 2020, Volume: 179

    Topics: Australia; Carbamates; Humans; Leucine; Male; Molecular Structure; Prostatic Neoplasms; Sesquiterpen

2020
Origins of Regioselectivity in the Fischer Indole Synthesis of a Selective Androgen Receptor Modulator.
    The Journal of organic chemistry, 2017, 06-02, Volume: 82, Issue:11

    Topics: Carbamates; Humans; Indoles; Male; Molecular Conformation; Molecular Dynamics Simulation; Prostatic

2017
Leveraging γ-Glutamyl Transferase To Direct Cytotoxicity of Copper Dithiocarbamates against Prostate Cancer Cells.
    Angewandte Chemie (International ed. in English), 2018, 09-24, Volume: 57, Issue:39

    Topics: Antineoplastic Agents; Carbamates; Cell Line, Tumor; Cell Survival; Copper; gamma-Glutamyltransferas

2018
PMS1077 sensitizes TNF-α induced apoptosis in human prostate cancer cells by blocking NF-κB signaling pathway.
    PloS one, 2013, Volume: 8, Issue:4

    Topics: Apoptosis; Carbamates; Cell Line, Tumor; Cell Nucleus; Enzyme Activation; Gene Expression; Gene Expr

2013
Identification of an anabolic selective androgen receptor modulator that actively induces death of androgen-independent prostate cancer cells.
    The Journal of steroid biochemistry and molecular biology, 2014, Volume: 143

    Topics: Anabolic Agents; Androgen Receptor Antagonists; Androgens; Animals; Apoptosis; Azasteroids; Blotting

2014
Design, chemical synthesis and biological evaluation of 3-spiromorpholinone/3-spirocarbamate androsterone derivatives as inhibitors of 17β-hydroxysteroid dehydrogenase type 3.
    Bioorganic & medicinal chemistry, 2015, Sep-01, Volume: 23, Issue:17

    Topics: 17-Hydroxysteroid Dehydrogenases; Androgens; Animals; Carbamates; Cell Line, Tumor; Drug Design; Enz

2015
A novel selective androgen receptor modulator (SARM) MK-4541 exerts anti-androgenic activity in the prostate cancer xenograft R-3327G and anabolic activity on skeletal muscle mass & function in castrated mice.
    The Journal of steroid biochemistry and molecular biology, 2016, Volume: 163

    Topics: Anabolic Agents; Androgen Antagonists; Animals; Antineoplastic Agents; Azasteroids; Carbamates; Carc

2016
Prostate cancer-associated mutation in SPOP impairs its ability to target Cdc20 for poly-ubiquitination and degradation.
    Cancer letters, 2017, 01-28, Volume: 385

    Topics: Antineoplastic Agents; Carbamates; Cdc20 Proteins; Cullin Proteins; Cyclopentanes; Diamines; Dose-Re

2017
Design, synthesis, and evaluation of novel mutual prodrugs (hybrid drugs) of all-trans-retinoic acid and histone deacetylase inhibitors with enhanced anticancer activities in breast and prostate cancer cells in vitro.
    Journal of medicinal chemistry, 2008, Jul-10, Volume: 51, Issue:13

    Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Carbamates; Cell Line, Tumor; Cell Proliferation;

2008
Synthesis of novel C17 steroidal carbamates. Studies on CYP17 action, androgen receptor binding and function, and prostate cancer cell growth.
    Steroids, 2008, Volume: 73, Issue:12

    Topics: Carbamates; Cell Division; Cell Line, Tumor; Humans; Magnetic Resonance Spectroscopy; Male; Prostati

2008
Antiproliferative effects of AVN944, a novel inosine 5-monophosphate dehydrogenase inhibitor, in prostate cancer cells.
    International journal of cancer, 2008, Nov-15, Volume: 123, Issue:10

    Topics: Androgens; Apoptosis; Carbamates; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Enzyme Inhibitor

2008
Effects of Iejimalide B, a marine macrolide, on growth and apoptosis in prostate cancer cell lines.
    Journal of cellular biochemistry, 2008, Nov-01, Volume: 105, Issue:4

    Topics: Apoptosis; Carbamates; Cell Cycle; Cell Cycle Proteins; Cell Line, Tumor; Cell Proliferation; Gene E

2008
Quinazoline-urea, new protein kinase inhibitors in treatment of prostate cancer.
    Journal of enzyme inhibition and medicinal chemistry, 2010, Volume: 25, Issue:2

    Topics: Amides; Antineoplastic Agents; Carbamates; Cell Line, Tumor; Cell Proliferation; Drug Screening Assa

2010
Synthesis and antitumor activity of ether glycerophospholipids bearing a carbamate moiety at the sn-2 position: selective sensitivity against prostate cancer cell lines.
    ChemMedChem, 2010, Jul-05, Volume: 5, Issue:7

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Apoptosis; Carbamates; Cell Line, Tumor; Drug

2010
miR-17* suppresses tumorigenicity of prostate cancer by inhibiting mitochondrial antioxidant enzymes.
    PloS one, 2010, Dec-22, Volume: 5, Issue:12

    Topics: Antioxidants; Carbamates; Cell Line, Tumor; Disulfiram; Gene Expression Regulation, Neoplastic; Glut

2010
Biological properties of androgen receptor pure antagonist for treatment of castration-resistant prostate cancer: optimization from lead compound to CH5137291.
    The Prostate, 2011, Volume: 71, Issue:12

    Topics: Androgen Antagonists; Androgen Receptor Antagonists; Anilides; Animals; Antineoplastic Agents; Carba

2011
A potent and selective inhibitor of KIAA1363/AADACL1 that impairs prostate cancer pathogenesis.
    Chemistry & biology, 2011, Apr-22, Volume: 18, Issue:4

    Topics: Animals; Carbamates; Cell Line, Tumor; Cell Movement; Cell Survival; Drug Discovery; Glyceryl Ethers

2011
Molecular editing and assessment of the cytotoxic properties of iejimalide and progeny.
    Chemistry (Weinheim an der Bergstrasse, Germany), 2011, Jun-14, Volume: 17, Issue:25

    Topics: Animals; Antineoplastic Agents; Apoptosis; Biological Products; Carbamates; Catalysis; Cell Line, Tu

2011
A novel steroidal antiandrogen targeting wild type and mutant androgen receptors.
    Biochemical pharmacology, 2011, Dec-01, Volume: 82, Issue:11

    Topics: Androgen Antagonists; Animals; Binding, Competitive; Carbamates; Cell Line, Tumor; Cell Proliferatio

2011
Notch signaling and ERK activation are important for the osteomimetic properties of prostate cancer bone metastatic cell lines.
    The Journal of biological chemistry, 2004, Jan-30, Volume: 279, Issue:5

    Topics: Basic Helix-Loop-Helix Transcription Factors; Blotting, Western; Bone Neoplasms; Calcium; Carbamates

2004
Evidence for calpain-mediated androgen receptor cleavage as a mechanism for androgen independence.
    Cancer research, 2007, Oct-01, Volume: 67, Issue:19

    Topics: Androgens; Animals; Apoptosis; Calpain; Carbamates; Cell Line, Tumor; Dipeptides; Enzyme Activation;

2007
Novel potent organoselenium compounds as cytotoxic agents in prostate cancer cells.
    Bioorganic & medicinal chemistry letters, 2007, Dec-15, Volume: 17, Issue:24

    Topics: Carbamates; Cell Line, Tumor; Cell Proliferation; Humans; Imides; Male; Molecular Structure; Organos

2007
Latrunculin A and its C-17-O-carbamates inhibit prostate tumor cell invasion and HIF-1 activation in breast tumor cells.
    Journal of natural products, 2008, Volume: 71, Issue:3

    Topics: Animals; Breast Neoplasms; Bridged Bicyclo Compounds, Heterocyclic; Carbamates; Drug Screening Assay

2008
Estramustine phosphate: metabolic aspects related to its action in prostatic cancer.
    The Journal of urology, 1978, Volume: 119, Issue:2

    Topics: Adenocarcinoma; Animals; Carbamates; Culture Techniques; Estradiol; Estramustine; Humans; Hydrolysis

1978
[Treatment of prostatic carcinoma with orally administered Estracyt].
    Therapeutische Umschau. Revue therapeutique, 1975, Volume: 32, Issue:2

    Topics: Administration, Oral; Carbamates; Drug Evaluation; Estranes; Humans; Male; Nitrogen Mustard Compound

1975
[Treatment with estramustine phosphate in advanced prostatic cancer].
    Wiener medizinische Wochenschrift (1946), 1972, Jul-22, Volume: 122, Issue:30

    Topics: Adenocarcinoma; Aged; Carbamates; Estranes; Humans; Male; Middle Aged; Nitrogen Mustard Compounds; P

1972
Proceedings: Cancer of the prostate.
    Cancer, 1973, Volume: 32, Issue:5

    Topics: Amides; Antineoplastic Agents; Arginase; Bleomycin; Busulfan; Carbamates; Chromomycins; Cyclic P-Oxi

1973
Stage D prostatic carcinoma. Survival rate in relapsed patients following new forms of palliation.
    Urology, 1974, Volume: 4, Issue:3

    Topics: Adrenalectomy; Carbamates; Estranes; Humans; Hypophysectomy; Male; Neoplasm Metastasis; Nitrogen Mus

1974
Estracyt (NSC 89199) as a substrate for phosphatases in human serum.
    Investigative urology, 1974, Volume: 12, Issue:1

    Topics: Acid Phosphatase; Alcohols; Alkaline Phosphatase; Antineoplastic Agents; Carbamates; Estranes; Human

1974
[Prostatic cancer--treatment with extramustine phosphate(Estracyt). An easier application form].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1974, Oct-10, Volume: 94, Issue:28

    Topics: Carbamates; Estradiol; Humans; Injections, Intra-Arterial; Male; Phosphates; Prostatic Neoplasms

1974
[Preliminary results of 10 patients with advanced prostatic neoplasm treated with estracyt].
    Acta urologica Belgica, 1974, Volume: 42, Issue:3

    Topics: Aged; Antineoplastic Agents; Bone Neoplasms; Carbamates; Estranes; Humans; Injections, Intravenous;

1974
Estracyt in hormone-resistant prostatic carcinoma.
    International urology and nephrology, 1974, Volume: 6, Issue:2

    Topics: Adult; Aged; Carbamates; Carcinoma; Drug Evaluation; Drug Resistance; Estranes; Follow-Up Studies; H

1974
Recent data on the mechanism of action of oestrogens in the treatment of prostatic tumour patients.
    International urology and nephrology, 1974, Volume: 5, Issue:3

    Topics: Aged; Antineoplastic Agents; Bone Neoplasms; Carbamates; Castration; Estranes; Humans; Iodine Radioi

1974
Pharmacoclinical study of oral estramustine phosphate (Estracyt) in advanced carcinoma of the prostate.
    Investigative urology, 1974, Volume: 12, Issue:1

    Topics: Acid Phosphatase; Administration, Oral; Antineoplastic Agents; Carbamates; Carcinoembryonic Antigen;

1974
Zinc and beta-glucuronidase in the human prostate.
    Scandinavian journal of urology and nephrology, 1974, Volume: 8, Issue:2

    Topics: Adenocarcinoma; Biopsy, Needle; Carbamates; Estradiol; Ethinyl Estradiol; Glucuronidase; Humans; Mal

1974
Treatment of rapidly progressing prostatic carcinoma with estracyt.
    The Journal of urology, 1972, Volume: 108, Issue:2

    Topics: Aged; Antineoplastic Agents; Carbamates; Estranes; Estrogens; Humans; Male; Middle Aged; Neoplasm Me

1972
[Cytostatic treatment of prostatic carcinoma. Evaluation study of estramustinphosphate].
    Schweizerische Rundschau fur Medizin Praxis = Revue suisse de medecine Praxis, 1971, Sep-21, Volume: 60, Issue:38

    Topics: Aged; Carbamates; Estrogens; Evaluation Studies as Topic; Humans; Male; Middle Aged; Nitrogen Mustar

1971
"Estracyt".
    British journal of urology, 1971, Volume: 43, Issue:6

    Topics: Carbamates; Estradiol; Humans; Male; Neoplasm Metastasis; Nitrogen Mustard Compounds; Prostatic Neop

1971