carbamates has been researched along with Atherogenesis in 11 studies
Excerpt | Relevance | Reference |
---|---|---|
"EXPANDING OUR KNOWLEDGE: Natural lipocyclocarbamate natural products have provided the inspiration for the first-in-class synthetic phospholipase inhibitor darapladib, currently in phase III clinical trials for the treatment of atherosclerosis." | 3.79 | Nonribosomal assembly of natural lipocyclocarbamate lipoprotein-associated phospholipase inhibitors. ( Johnston, CW; Khyzha, N; Magarvey, NA; Zvanych, R, 2013) |
"Experimental diabetes mellitus was produced by a single intraperitoneal injection of STZ (55mg/kg b." | 1.43 | Antihyperglycemic and antidiabetic effects of Ethyl (S)-2-(1-cyclohexylsulfamide carbamoyloxy) propanoate in streptozotocin-induced diabetic Wistar rats. ( Berredjem, H; Berredjem, M; Bouzerna, N; Cheloufi, H; Réggami, Y, 2016) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 5 (45.45) | 29.6817 |
2010's | 6 (54.55) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Spinelli, FR | 1 |
Pecani, A | 1 |
Ciciarello, F | 1 |
Colasanti, T | 1 |
Di Franco, M | 1 |
Miranda, F | 1 |
Conti, F | 1 |
Valesini, G | 1 |
Alessandri, C | 1 |
Apostolov, EO | 1 |
Ok, E | 1 |
Burns, S | 1 |
Nawaz, S | 1 |
Savenka, A | 1 |
Shah, S | 1 |
Basnakian, AG | 1 |
Ketelhuth, DF | 1 |
Hermansson, A | 1 |
Hlawaty, H | 1 |
Letourneur, D | 1 |
Yan, ZQ | 2 |
Bäck, M | 2 |
Réggami, Y | 1 |
Berredjem, H | 1 |
Cheloufi, H | 1 |
Berredjem, M | 1 |
Bouzerna, N | 1 |
Lenglet, S | 1 |
Thomas, A | 1 |
Soehnlein, O | 1 |
Montecucco, F | 1 |
Burger, F | 1 |
Pelli, G | 1 |
Galan, K | 1 |
Cravatt, B | 1 |
Staub, C | 1 |
Steffens, S | 1 |
Johnston, CW | 1 |
Zvanych, R | 1 |
Khyzha, N | 1 |
Magarvey, NA | 1 |
Kodvawala, A | 1 |
Ghering, AB | 1 |
Davidson, WS | 1 |
Hui, DY | 1 |
Bu, DX | 1 |
Bränström, R | 1 |
Sheikine, Y | 1 |
Hansson, GK | 1 |
Allred, KF | 1 |
Smart, EJ | 1 |
Wilson, ME | 1 |
Wang, Z | 1 |
Nicholls, SJ | 1 |
Rodriguez, ER | 1 |
Kummu, O | 1 |
Hörkkö, S | 1 |
Barnard, J | 1 |
Reynolds, WF | 1 |
Topol, EJ | 1 |
DiDonato, JA | 1 |
Hazen, SL | 1 |
Rader, DJ | 1 |
Ischiropoulos, H | 1 |
Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
Clinical Follow-up of Anti-Carbamylated Antibody Status in Rheumatoid Arthritis Patients at 6, 12 and 18 Months[NCT02958319] | 278 participants (Actual) | Observational | 2016-06-30 | Completed | |||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
"To explore the clinical differences in activity indexes (DAS28-ESR) at 6, 12 and 18 months of follow-up according the anti-CarP status.~The DAS28 is a composite score derived from 4 measures, one of them can be the erythrocyte sedimentation rate (ESR). We will be using the DAS28-ESR version. To calculate the DAS28-ESR the rheumatologist or specialist nurse will:- count the number of swollen joints (out of the 28), count the number of tender joints (out of the 28), take blood to measure ESR, ask participants to make a 'global assessment of health' (indicated by marking a 10 cm line between very good and very bad).~DAS28-ESR is calculated with classic calculators and resulting values are interpreted as follows:~<2.6: disease remission 2.6 - 3.2: low disease activity 3.2 - 5.1: moderate disease activity >5.1: high disease activity" (NCT02958319)
Timeframe: 6, 12 and 18 Months
Intervention | units on a scale (Mean) | ||
---|---|---|---|
6 MONTHS | 12 MONTHS | 18 MONTHS | |
Anti P Carb Negative RA Patients | 3.75 | 3.59 | 3.65 |
Anti P Carb Positive RA Patients | 3.72 | 3.69 | 3.77 |
11 other studies available for carbamates and Atherogenesis
Article | Year |
---|---|
Association between antibodies to carbamylated proteins and subclinical atherosclerosis in rheumatoid arthritis patients.
Topics: Adult; Aged; Arthritis, Rheumatoid; Atherosclerosis; Autoantibodies; Blood Proteins; Carbamates; Car | 2017 |
Carbamylated-oxidized LDL: proatherosclerotic effects on endothelial cells and macrophages.
Topics: Atherosclerosis; Carbamates; Cell Death; Cells, Cultured; Endothelium, Vascular; Enzyme-Linked Immun | 2013 |
The leukotriene B4 receptor (BLT) antagonist BIIL284 decreases atherosclerosis in ApoE-/- mice.
Topics: Amidines; Animals; Apolipoproteins E; Atherosclerosis; Carbamates; Cytokines; Male; Matrix Metallopr | 2015 |
Antihyperglycemic and antidiabetic effects of Ethyl (S)-2-(1-cyclohexylsulfamide carbamoyloxy) propanoate in streptozotocin-induced diabetic Wistar rats.
Topics: Animals; Atherosclerosis; Bilirubin; Blood Glucose; Body Weight; Carbamates; Creatinine; Diabetes Me | 2016 |
Fatty acid amide hydrolase deficiency enhances intraplaque neutrophil recruitment in atherosclerotic mice.
Topics: Amides; Amidohydrolases; Animals; Aorta; Aortic Diseases; Apolipoproteins E; Arachidonic Acids; Athe | 2013 |
Nonribosomal assembly of natural lipocyclocarbamate lipoprotein-associated phospholipase inhibitors.
Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Atherosclerosis; Benzaldehydes; Biological Products; | 2013 |
Carboxyl ester lipase expression in macrophages increases cholesteryl ester accumulation and promotes atherosclerosis.
Topics: Animals; Apolipoproteins E; Atherosclerosis; Biological Transport; Carbamates; Carboxylesterase; Cer | 2005 |
Leukotriene B4 signaling through NF-kappaB-dependent BLT1 receptors on vascular smooth muscle cells in atherosclerosis and intimal hyperplasia.
Topics: Amidines; Analysis of Variance; Animals; Atherosclerosis; Blotting, Western; Carbamates; Carotid Art | 2005 |
Estrogen receptor-alpha mediates gender differences in atherosclerosis induced by HIV protease inhibitors.
Topics: Animals; Atherosclerosis; Carbamates; Cholesterol; Estrogen Receptor alpha; Female; Furans; HIV Prot | 2006 |
Protein carbamylation links inflammation, smoking, uremia and atherogenesis.
Topics: Animals; Atherosclerosis; Blood Proteins; Carbamates; Cholesterol; Citrulline; Clinical Trials as To | 2007 |
'Multipurpose oxidase' in atherogenesis.
Topics: Animals; Apoptosis; Atherosclerosis; Carbamates; Cardiovascular Diseases; Cell Proliferation; Citrul | 2007 |