carbamates has been researched along with Aneuploid in 23 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "Peri-fertilization exposure to Carbendazim (MBC; a microtubule poison) induces infertility and early pregnancy loss in hamsters." | 7.69 | Carbendazim (MBC) disrupts oocyte spindle function and induces aneuploidy in hamsters exposed during fertilization (meiosis II). ( Perreault, SD; Zuelke, KA, 1995) |
| " Dose-response data were generated over a range of closely spaced concentrations at 100 ng/ml intervals." | 5.31 | Evaluation of thresholds for benomyl- and carbendazim-induced aneuploidy in cultured human lymphocytes using fluorescence in situ hybridization. ( Bentley, KS; Kirkland, D; Marshall, R; Murphy, M, 2000) |
| " Microtubule-stabilizing agents including Taxol, epothilone B, and discodermolide produce aneuploid populations of A549 cells in the absence of a mitotic block." | 3.71 | Differential mitotic responses to microtubule-stabilizing and -destabilizing drugs. ( Chen, JG; Horwitz, SB, 2002) |
| "Peri-fertilization exposure to Carbendazim (MBC; a microtubule poison) induces infertility and early pregnancy loss in hamsters." | 3.69 | Carbendazim (MBC) disrupts oocyte spindle function and induces aneuploidy in hamsters exposed during fertilization (meiosis II). ( Perreault, SD; Zuelke, KA, 1995) |
| "Cytochalasin B-blocked binucleate human lymphocytes from female donors have been used to measure micronucleus induction and other aneuploidy events after treatment with colchicine, vinblastine or carbendazim." | 3.69 | Fluorescence in situ hybridisation with chromosome-specific centromeric probes: a sensitive method to detect aneuploidy. ( Bentley, KS; Kirkland, DJ; Marshall, RR; Murphy, M, 1996) |
| "The utility of Chinese hamsters as a test species for aneuploidy analysis was studied using four chemicals--vincristine, methyl 2-benzimidazole carbamate (MBC), nocodazole, and cyclophosphamide." | 3.68 | The feasibility of using Chinese hamsters as an animal model for aneuploidy. ( Arras, CA; Jones, RL; Lavappa, KS; Lee, JK; Sheu, CW, 1990) |
| "Nocodazole, ethyl acetate, acetone and methyl ethyl ketone all are known to induce aneuploidy." | 3.67 | Effects of chemical combinations on the induction of aneuploidy in Saccharomyces cerevisiae. ( Goin, CJ; Mayer, VW, 1987) |
| "To study the origin of induced aneuploid cells, the BrUdR-labelling technique was applied to V79/AP4 Chinese hamster cells treated with colcemid or benomyl." | 3.67 | Analysis by BrUdR-labelling technique of induced aneuploidy in mammalian cells in culture. ( Colella, CM; Flori, L; Mariani, T; Piras, A; Rainaldi, G; Simi, S; Simili, M, 1987) |
| "Our results suggest that elimination of aneuploid cells does occur." | 1.31 | Elimination of micronucleated cells by apoptosis after treatment with inhibitors of microtubules. ( Cundari, E; Decordier, I; Dillen, L; Kirsch-Volders, M, 2002) |
| " Dose-response data were generated over a range of closely spaced concentrations at 100 ng/ml intervals." | 1.31 | Evaluation of thresholds for benomyl- and carbendazim-induced aneuploidy in cultured human lymphocytes using fluorescence in situ hybridization. ( Bentley, KS; Kirkland, D; Marshall, R; Murphy, M, 2000) |
| "The induction of aneuploidy by DZ was also tested in humans." | 1.31 | Induction of aneuploidy in male mouse germ cells detected by the sperm-FISH assay: a review of the present data base. ( Adler, ID; Baumgartner, A; Schmid, TE, 2002) |
| " But since it is obvious from dose-response curves where the inflection point/threshold lies, it appears that the model might be picking up some irregularities (possibly due to experimental variability in the dose-response curve at concentrations greater than the threshold)." | 1.30 | Indication for thresholds of chromosome non-disjunction versus chromosome lagging induced by spindle inhibitors in vitro in human lymphocytes. ( Elhajouji, A; Kirsch-Volders, M; Tibaldi, F, 1997) |
| "22% in the highest dose group, the observed dose-response relationship was highly significant." | 1.30 | Increased frequencies of diploid sperm detected by multicolour FISH after treatment of rats with carbendazim without micronucleus induction in peripheral blood erythrocytes. ( Bedaf, M; de Stoppelaar, JM; Hoebee, B; Mohn, GR; Slob, W; van Benthem, J; van de Kuil, T; Verharen, HW, 1999) |
| " MBC and MEB are poorly soluble in water and therefore have a low bioavailability in vivo." | 1.29 | Clastogenic and aneugenic effects of three benzimidazole derivatives in the in vitro micronucleus test using human lymphocytes. ( Elhajouji, A; Kirsch-Volders, M; Van Hummelen, P, 1995) |
| "Comparison of the induced rates of aneuploidy i indicates that these can exhibit departures from simple additivity to the spontaneous rates: induced rates in the ZESTE system are generally higher and more variable than those from FIX." | 1.28 | Aneuploidy in Drosophila, II. Further validation of the FIX and ZESTE genetic test systems employing female Drosophila melanogaster. ( Mason, JM; Osgood, C; Zimmering, S, 1991) |
| "The state of aneuploidy test methodology was appraised by the U." | 1.28 | Reevaluation of the 9 compounds reported conclusive positive in yeast Saccharomyces cerevisiae aneuploidy test systems by the Gene-Tox Program using strain D61.M of Saccharomyces cerevisiae. ( Albertini, S, 1991) |
| "Benomyl was negative in the Ames test." | 1.28 | Genotoxic activity of benomyl in different test systems. ( Georgieva, V; Kappas, A; Tzoneva, M; Vachkova, R, 1990) |
| " The test relies on a gene dosage selection system in which hyperploidy is detected by the simultaneous increase in copy number of two alleles residing on the right arm of chromosome VIII: arg4-8 and cup1S (Rockmill and Fogel." | 1.28 | The detection of mitotic and meiotic chromosome gain in the yeast Saccharomyces cerevisiae: effects of methyl benzimidazol-2-yl carbamate, methyl methanesulfonate, ethyl methanesulfonate, dimethyl sulfoxide, propionitrile and cyclophosphamide monohydrate. ( Fogel, S; Maloney, DH; Moser, SF; Piegorsch, WW; Resnick, MA; Whittaker, SG, 1990) |
| " Monitoring gene dosage changes at two loci on chromosome VIII, the test utilizes a leaky temperature-sensitive allele arg4-8 and low level copper resistance conferred by the single copy allele cup1s." | 1.27 | The detection of mitotic and meiotic aneuploidy in yeast using a gene dosage selection system. ( Blechl, AE; Fogel, S; Maloney, DH; Resnick, MA; Rockmill, BM; Whittaker, SG, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (17.39) | 18.7374 |
| 1990's | 15 (65.22) | 18.2507 |
| 2000's | 4 (17.39) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Decordier, I | 1 |
| Dillen, L | 1 |
| Cundari, E | 1 |
| Kirsch-Volders, M | 5 |
| Sarrif, AM | 1 |
| Bentley, KS | 3 |
| Fu, LJ | 1 |
| O'Neil, RM | 1 |
| Reynolds, VL | 1 |
| Stahl, RG | 1 |
| Van Hummelen, P | 3 |
| Nüsse, M | 1 |
| Castelain, P | 1 |
| Barale, R | 1 |
| Scapoli, C | 1 |
| Meli, C | 1 |
| Casini, D | 1 |
| Minunni, M | 1 |
| Marrazzini, A | 1 |
| Loprieno, N | 1 |
| Barrai, I | 1 |
| Elhajouji, A | 3 |
| Zuelke, KA | 1 |
| Perreault, SD | 1 |
| Marshall, RR | 1 |
| Murphy, M | 2 |
| Kirkland, DJ | 1 |
| Tibaldi, F | 1 |
| de Stoppelaar, JM | 1 |
| van de Kuil, T | 1 |
| Bedaf, M | 1 |
| Verharen, HW | 1 |
| Slob, W | 1 |
| Mohn, GR | 1 |
| Hoebee, B | 1 |
| van Benthem, J | 1 |
| Kirkland, D | 1 |
| Marshall, R | 1 |
| Chen, JG | 1 |
| Horwitz, SB | 1 |
| Adler, ID | 1 |
| Schmid, TE | 1 |
| Baumgartner, A | 1 |
| Barton, RC | 1 |
| Gull, K | 1 |
| Osgood, C | 1 |
| Zimmering, S | 1 |
| Mason, JM | 1 |
| Albertini, S | 1 |
| Georgieva, V | 1 |
| Vachkova, R | 1 |
| Tzoneva, M | 1 |
| Kappas, A | 1 |
| Sheu, CW | 1 |
| Lee, JK | 1 |
| Arras, CA | 1 |
| Jones, RL | 1 |
| Lavappa, KS | 1 |
| Whittaker, SG | 2 |
| Moser, SF | 1 |
| Maloney, DH | 2 |
| Piegorsch, WW | 1 |
| Resnick, MA | 2 |
| Fogel, S | 2 |
| Rockmill, BM | 1 |
| Blechl, AE | 1 |
| Hummler, E | 1 |
| Hansmann, I | 1 |
| Mayer, VW | 1 |
| Goin, CJ | 1 |
| Rainaldi, G | 1 |
| Flori, L | 1 |
| Colella, CM | 1 |
| Mariani, T | 1 |
| Piras, A | 1 |
| Simi, S | 1 |
| Simili, M | 1 |
23 other studies available for carbamates and Aneuploid
| Article | Year |
|---|---|
Elimination of micronucleated cells by apoptosis after treatment with inhibitors of microtubules.
Topics: Adult; Aneuploidy; Apoptosis; Benzimidazoles; Carbamates; Cell Nucleus; Cells, Cultured; Chromosome | 2002 |
Evaluation of benomyl and carbendazim in the in vivo aneuploidy/micronucleus assay in BDF1 mouse bone marrow.
Topics: Aneuploidy; Animals; Benomyl; Benzimidazoles; Bone Marrow; Bone Marrow Cells; Carbamates; Female; Ma | 1994 |
Aneugen-induced micronuclei (MN) in human lymphocytes may be discerned using image analysis techniques when cell-cycle stage is taken into account.
Topics: Aneuploidy; Benzimidazoles; Carbamates; Cell Cycle; Cells, Cultured; Coloring Agents; Cytochalasin B | 1995 |
Cytogenetic effects of benzimidazoles in mouse bone marrow.
Topics: Analysis of Variance; Aneuploidy; Animals; Benomyl; Benzimidazoles; Bone Marrow; Bone Marrow Cells; | 1993 |
Clastogenic and aneugenic effects of three benzimidazole derivatives in the in vitro micronucleus test using human lymphocytes.
Topics: Adult; Aneuploidy; Animals; Benzimidazoles; Biotransformation; Carbamates; Cells, Cultured; Chromoso | 1995 |
Carbendazim (MBC) disrupts oocyte spindle function and induces aneuploidy in hamsters exposed during fertilization (meiosis II).
Topics: Aneuploidy; Animals; Benzimidazoles; Carbamates; Cricetinae; Female; Fertilization; Fertilization in | 1995 |
Indications for a threshold of chemically-induced aneuploidy in vitro in human lymphocytes.
Topics: Adult; Aneuploidy; Benzimidazoles; Carbamates; Cell Division; Cell Survival; Cells, Cultured; Centro | 1995 |
Fluorescence in situ hybridisation with chromosome-specific centromeric probes: a sensitive method to detect aneuploidy.
Topics: Adult; Aneuploidy; Benzimidazoles; Carbamates; Cells, Cultured; Centromere; Colchicine; Cytochalasin | 1996 |
Indication for thresholds of chromosome non-disjunction versus chromosome lagging induced by spindle inhibitors in vitro in human lymphocytes.
Topics: Adult; Aneuploidy; Benzimidazoles; Carbamates; Chromosomes, Human; Chromosomes, Human, Pair 1; Chrom | 1997 |
Increased frequencies of diploid sperm detected by multicolour FISH after treatment of rats with carbendazim without micronucleus induction in peripheral blood erythrocytes.
Topics: Administration, Oral; Aneuploidy; Animals; Benzimidazoles; Carbamates; Diploidy; Dose-Response Relat | 1999 |
Evaluation of thresholds for benomyl- and carbendazim-induced aneuploidy in cultured human lymphocytes using fluorescence in situ hybridization.
Topics: Adult; Aneuploidy; Benomyl; Benzimidazoles; Carbamates; Cells, Cultured; Dose-Response Relationship, | 2000 |
Differential mitotic responses to microtubule-stabilizing and -destabilizing drugs.
Topics: Alkanes; Aneuploidy; Antineoplastic Agents; Carbamates; Carcinoma, Non-Small-Cell Lung; Epothilones; | 2002 |
Induction of aneuploidy in male mouse germ cells detected by the sperm-FISH assay: a review of the present data base.
Topics: Acrylamide; Aneuploidy; Animals; Benzimidazoles; Carbamates; Colchicine; Diazepam; Griseofulvin; Hum | 2002 |
Isolation, characterization, and genetic analysis of monosomic, aneuploid mutants of Candida albicans.
Topics: Aneuploidy; Benzimidazoles; Candida albicans; Carbamates; Colony Count, Microbial; Electrophoresis, | 1992 |
Aneuploidy in Drosophila, II. Further validation of the FIX and ZESTE genetic test systems employing female Drosophila melanogaster.
Topics: Acetates; Acetonitriles; Aneuploidy; Animals; Antifungal Agents; Benzimidazoles; Cadmium; Cadmium Ch | 1991 |
Reevaluation of the 9 compounds reported conclusive positive in yeast Saccharomyces cerevisiae aneuploidy test systems by the Gene-Tox Program using strain D61.M of Saccharomyces cerevisiae.
Topics: Acetone; Aneuploidy; Benomyl; Benzimidazoles; Biotransformation; Carbamates; Chromosomes, Fungal; Cy | 1991 |
Genotoxic activity of benomyl in different test systems.
Topics: Aneuploidy; Animals; Benomyl; Biotransformation; Carbamates; Cell Division; Cells, Cultured; Female; | 1990 |
The feasibility of using Chinese hamsters as an animal model for aneuploidy.
Topics: Aneuploidy; Animals; Benzimidazoles; Bone Marrow; Carbamates; Cricetinae; Cricetulus; Cyclophosphami | 1990 |
The detection of mitotic and meiotic chromosome gain in the yeast Saccharomyces cerevisiae: effects of methyl benzimidazol-2-yl carbamate, methyl methanesulfonate, ethyl methanesulfonate, dimethyl sulfoxide, propionitrile and cyclophosphamide monohydrate.
Topics: Aneuploidy; Benzimidazoles; Carbamates; Chromosomes, Fungal; Cyclophosphamide; Dimethyl Sulfoxide; E | 1990 |
The detection of mitotic and meiotic aneuploidy in yeast using a gene dosage selection system.
Topics: Aneuploidy; Benzimidazoles; Carbamates; Genes, Fungal; Genetic Markers; Meiosis; Mitosis; Saccharomy | 1988 |
Pattern and frequency of nondisjunction in oocytes from the Djungarian hamster are determined by the stage of first meiotic spindle inhibition.
Topics: Aneuploidy; Animals; Benzimidazoles; Carbamates; Chorionic Gonadotropin; Cricetinae; Female; Liver; | 1988 |
Effects of chemical combinations on the induction of aneuploidy in Saccharomyces cerevisiae.
Topics: Acetates; Acetone; Aneuploidy; Benzimidazoles; Butanones; Carbamates; Dimethyl Sulfoxide; Dimethylfo | 1987 |
Analysis by BrUdR-labelling technique of induced aneuploidy in mammalian cells in culture.
Topics: Aneuploidy; Animals; Benomyl; Bromodeoxyuridine; Carbamates; Cell Division; Cell Line; Cricetinae; D | 1987 |