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carbamates and Aneuploid

carbamates has been researched along with Aneuploid in 23 studies

Research Excerpts

ExcerptRelevanceReference
"Peri-fertilization exposure to Carbendazim (MBC; a microtubule poison) induces infertility and early pregnancy loss in hamsters."7.69Carbendazim (MBC) disrupts oocyte spindle function and induces aneuploidy in hamsters exposed during fertilization (meiosis II). ( Perreault, SD; Zuelke, KA, 1995)
" Dose-response data were generated over a range of closely spaced concentrations at 100 ng/ml intervals."5.31Evaluation of thresholds for benomyl- and carbendazim-induced aneuploidy in cultured human lymphocytes using fluorescence in situ hybridization. ( Bentley, KS; Kirkland, D; Marshall, R; Murphy, M, 2000)
" Microtubule-stabilizing agents including Taxol, epothilone B, and discodermolide produce aneuploid populations of A549 cells in the absence of a mitotic block."3.71Differential mitotic responses to microtubule-stabilizing and -destabilizing drugs. ( Chen, JG; Horwitz, SB, 2002)
"Peri-fertilization exposure to Carbendazim (MBC; a microtubule poison) induces infertility and early pregnancy loss in hamsters."3.69Carbendazim (MBC) disrupts oocyte spindle function and induces aneuploidy in hamsters exposed during fertilization (meiosis II). ( Perreault, SD; Zuelke, KA, 1995)
"Cytochalasin B-blocked binucleate human lymphocytes from female donors have been used to measure micronucleus induction and other aneuploidy events after treatment with colchicine, vinblastine or carbendazim."3.69Fluorescence in situ hybridisation with chromosome-specific centromeric probes: a sensitive method to detect aneuploidy. ( Bentley, KS; Kirkland, DJ; Marshall, RR; Murphy, M, 1996)
"The utility of Chinese hamsters as a test species for aneuploidy analysis was studied using four chemicals--vincristine, methyl 2-benzimidazole carbamate (MBC), nocodazole, and cyclophosphamide."3.68The feasibility of using Chinese hamsters as an animal model for aneuploidy. ( Arras, CA; Jones, RL; Lavappa, KS; Lee, JK; Sheu, CW, 1990)
"Nocodazole, ethyl acetate, acetone and methyl ethyl ketone all are known to induce aneuploidy."3.67Effects of chemical combinations on the induction of aneuploidy in Saccharomyces cerevisiae. ( Goin, CJ; Mayer, VW, 1987)
"To study the origin of induced aneuploid cells, the BrUdR-labelling technique was applied to V79/AP4 Chinese hamster cells treated with colcemid or benomyl."3.67Analysis by BrUdR-labelling technique of induced aneuploidy in mammalian cells in culture. ( Colella, CM; Flori, L; Mariani, T; Piras, A; Rainaldi, G; Simi, S; Simili, M, 1987)
"Our results suggest that elimination of aneuploid cells does occur."1.31Elimination of micronucleated cells by apoptosis after treatment with inhibitors of microtubules. ( Cundari, E; Decordier, I; Dillen, L; Kirsch-Volders, M, 2002)
" Dose-response data were generated over a range of closely spaced concentrations at 100 ng/ml intervals."1.31Evaluation of thresholds for benomyl- and carbendazim-induced aneuploidy in cultured human lymphocytes using fluorescence in situ hybridization. ( Bentley, KS; Kirkland, D; Marshall, R; Murphy, M, 2000)
"The induction of aneuploidy by DZ was also tested in humans."1.31Induction of aneuploidy in male mouse germ cells detected by the sperm-FISH assay: a review of the present data base. ( Adler, ID; Baumgartner, A; Schmid, TE, 2002)
" But since it is obvious from dose-response curves where the inflection point/threshold lies, it appears that the model might be picking up some irregularities (possibly due to experimental variability in the dose-response curve at concentrations greater than the threshold)."1.30Indication for thresholds of chromosome non-disjunction versus chromosome lagging induced by spindle inhibitors in vitro in human lymphocytes. ( Elhajouji, A; Kirsch-Volders, M; Tibaldi, F, 1997)
"22% in the highest dose group, the observed dose-response relationship was highly significant."1.30Increased frequencies of diploid sperm detected by multicolour FISH after treatment of rats with carbendazim without micronucleus induction in peripheral blood erythrocytes. ( Bedaf, M; de Stoppelaar, JM; Hoebee, B; Mohn, GR; Slob, W; van Benthem, J; van de Kuil, T; Verharen, HW, 1999)
" MBC and MEB are poorly soluble in water and therefore have a low bioavailability in vivo."1.29Clastogenic and aneugenic effects of three benzimidazole derivatives in the in vitro micronucleus test using human lymphocytes. ( Elhajouji, A; Kirsch-Volders, M; Van Hummelen, P, 1995)
"Comparison of the induced rates of aneuploidy i indicates that these can exhibit departures from simple additivity to the spontaneous rates: induced rates in the ZESTE system are generally higher and more variable than those from FIX."1.28Aneuploidy in Drosophila, II. Further validation of the FIX and ZESTE genetic test systems employing female Drosophila melanogaster. ( Mason, JM; Osgood, C; Zimmering, S, 1991)
"The state of aneuploidy test methodology was appraised by the U."1.28Reevaluation of the 9 compounds reported conclusive positive in yeast Saccharomyces cerevisiae aneuploidy test systems by the Gene-Tox Program using strain D61.M of Saccharomyces cerevisiae. ( Albertini, S, 1991)
"Benomyl was negative in the Ames test."1.28Genotoxic activity of benomyl in different test systems. ( Georgieva, V; Kappas, A; Tzoneva, M; Vachkova, R, 1990)
" The test relies on a gene dosage selection system in which hyperploidy is detected by the simultaneous increase in copy number of two alleles residing on the right arm of chromosome VIII: arg4-8 and cup1S (Rockmill and Fogel."1.28The detection of mitotic and meiotic chromosome gain in the yeast Saccharomyces cerevisiae: effects of methyl benzimidazol-2-yl carbamate, methyl methanesulfonate, ethyl methanesulfonate, dimethyl sulfoxide, propionitrile and cyclophosphamide monohydrate. ( Fogel, S; Maloney, DH; Moser, SF; Piegorsch, WW; Resnick, MA; Whittaker, SG, 1990)
" Monitoring gene dosage changes at two loci on chromosome VIII, the test utilizes a leaky temperature-sensitive allele arg4-8 and low level copper resistance conferred by the single copy allele cup1s."1.27The detection of mitotic and meiotic aneuploidy in yeast using a gene dosage selection system. ( Blechl, AE; Fogel, S; Maloney, DH; Resnick, MA; Rockmill, BM; Whittaker, SG, 1988)

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-19904 (17.39)18.7374
1990's15 (65.22)18.2507
2000's4 (17.39)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Decordier, I1
Dillen, L1
Cundari, E1
Kirsch-Volders, M5
Sarrif, AM1
Bentley, KS3
Fu, LJ1
O'Neil, RM1
Reynolds, VL1
Stahl, RG1
Van Hummelen, P3
NĂ¼sse, M1
Castelain, P1
Barale, R1
Scapoli, C1
Meli, C1
Casini, D1
Minunni, M1
Marrazzini, A1
Loprieno, N1
Barrai, I1
Elhajouji, A3
Zuelke, KA1
Perreault, SD1
Marshall, RR1
Murphy, M2
Kirkland, DJ1
Tibaldi, F1
de Stoppelaar, JM1
van de Kuil, T1
Bedaf, M1
Verharen, HW1
Slob, W1
Mohn, GR1
Hoebee, B1
van Benthem, J1
Kirkland, D1
Marshall, R1
Chen, JG1
Horwitz, SB1
Adler, ID1
Schmid, TE1
Baumgartner, A1
Barton, RC1
Gull, K1
Osgood, C1
Zimmering, S1
Mason, JM1
Albertini, S1
Georgieva, V1
Vachkova, R1
Tzoneva, M1
Kappas, A1
Sheu, CW1
Lee, JK1
Arras, CA1
Jones, RL1
Lavappa, KS1
Whittaker, SG2
Moser, SF1
Maloney, DH2
Piegorsch, WW1
Resnick, MA2
Fogel, S2
Rockmill, BM1
Blechl, AE1
Hummler, E1
Hansmann, I1
Mayer, VW1
Goin, CJ1
Rainaldi, G1
Flori, L1
Colella, CM1
Mariani, T1
Piras, A1
Simi, S1
Simili, M1

Other Studies

23 other studies available for carbamates and Aneuploid

ArticleYear
Elimination of micronucleated cells by apoptosis after treatment with inhibitors of microtubules.
    Mutagenesis, 2002, Volume: 17, Issue:4

    Topics: Adult; Aneuploidy; Apoptosis; Benzimidazoles; Carbamates; Cell Nucleus; Cells, Cultured; Chromosome

2002
Evaluation of benomyl and carbendazim in the in vivo aneuploidy/micronucleus assay in BDF1 mouse bone marrow.
    Mutation research, 1994, Oct-01, Volume: 310, Issue:1

    Topics: Aneuploidy; Animals; Benomyl; Benzimidazoles; Bone Marrow; Bone Marrow Cells; Carbamates; Female; Ma

1994
Aneugen-induced micronuclei (MN) in human lymphocytes may be discerned using image analysis techniques when cell-cycle stage is taken into account.
    Environmental and molecular mutagenesis, 1995, Volume: 25, Issue:4

    Topics: Aneuploidy; Benzimidazoles; Carbamates; Cell Cycle; Cells, Cultured; Coloring Agents; Cytochalasin B

1995
Cytogenetic effects of benzimidazoles in mouse bone marrow.
    Mutation research, 1993, Volume: 300, Issue:1

    Topics: Analysis of Variance; Aneuploidy; Animals; Benomyl; Benzimidazoles; Bone Marrow; Bone Marrow Cells;

1993
Clastogenic and aneugenic effects of three benzimidazole derivatives in the in vitro micronucleus test using human lymphocytes.
    Mutagenesis, 1995, Volume: 10, Issue:1

    Topics: Adult; Aneuploidy; Animals; Benzimidazoles; Biotransformation; Carbamates; Cells, Cultured; Chromoso

1995
Carbendazim (MBC) disrupts oocyte spindle function and induces aneuploidy in hamsters exposed during fertilization (meiosis II).
    Molecular reproduction and development, 1995, Volume: 42, Issue:2

    Topics: Aneuploidy; Animals; Benzimidazoles; Carbamates; Cricetinae; Female; Fertilization; Fertilization in

1995
Indications for a threshold of chemically-induced aneuploidy in vitro in human lymphocytes.
    Environmental and molecular mutagenesis, 1995, Volume: 26, Issue:4

    Topics: Adult; Aneuploidy; Benzimidazoles; Carbamates; Cell Division; Cell Survival; Cells, Cultured; Centro

1995
Fluorescence in situ hybridisation with chromosome-specific centromeric probes: a sensitive method to detect aneuploidy.
    Mutation research, 1996, Volume: 372, Issue:2

    Topics: Adult; Aneuploidy; Benzimidazoles; Carbamates; Cells, Cultured; Centromere; Colchicine; Cytochalasin

1996
Indication for thresholds of chromosome non-disjunction versus chromosome lagging induced by spindle inhibitors in vitro in human lymphocytes.
    Mutagenesis, 1997, Volume: 12, Issue:3

    Topics: Adult; Aneuploidy; Benzimidazoles; Carbamates; Chromosomes, Human; Chromosomes, Human, Pair 1; Chrom

1997
Increased frequencies of diploid sperm detected by multicolour FISH after treatment of rats with carbendazim without micronucleus induction in peripheral blood erythrocytes.
    Mutagenesis, 1999, Volume: 14, Issue:6

    Topics: Administration, Oral; Aneuploidy; Animals; Benzimidazoles; Carbamates; Diploidy; Dose-Response Relat

1999
Evaluation of thresholds for benomyl- and carbendazim-induced aneuploidy in cultured human lymphocytes using fluorescence in situ hybridization.
    Mutation research, 2000, Jan-03, Volume: 464, Issue:1

    Topics: Adult; Aneuploidy; Benomyl; Benzimidazoles; Carbamates; Cells, Cultured; Dose-Response Relationship,

2000
Differential mitotic responses to microtubule-stabilizing and -destabilizing drugs.
    Cancer research, 2002, Apr-01, Volume: 62, Issue:7

    Topics: Alkanes; Aneuploidy; Antineoplastic Agents; Carbamates; Carcinoma, Non-Small-Cell Lung; Epothilones;

2002
Induction of aneuploidy in male mouse germ cells detected by the sperm-FISH assay: a review of the present data base.
    Mutation research, 2002, Jul-25, Volume: 504, Issue:1-2

    Topics: Acrylamide; Aneuploidy; Animals; Benzimidazoles; Carbamates; Colchicine; Diazepam; Griseofulvin; Hum

2002
Isolation, characterization, and genetic analysis of monosomic, aneuploid mutants of Candida albicans.
    Molecular microbiology, 1992, Volume: 6, Issue:2

    Topics: Aneuploidy; Benzimidazoles; Candida albicans; Carbamates; Colony Count, Microbial; Electrophoresis,

1992
Aneuploidy in Drosophila, II. Further validation of the FIX and ZESTE genetic test systems employing female Drosophila melanogaster.
    Mutation research, 1991, Volume: 259, Issue:2

    Topics: Acetates; Acetonitriles; Aneuploidy; Animals; Antifungal Agents; Benzimidazoles; Cadmium; Cadmium Ch

1991
Reevaluation of the 9 compounds reported conclusive positive in yeast Saccharomyces cerevisiae aneuploidy test systems by the Gene-Tox Program using strain D61.M of Saccharomyces cerevisiae.
    Mutation research, 1991, Volume: 260, Issue:2

    Topics: Acetone; Aneuploidy; Benomyl; Benzimidazoles; Biotransformation; Carbamates; Chromosomes, Fungal; Cy

1991
Genotoxic activity of benomyl in different test systems.
    Environmental and molecular mutagenesis, 1990, Volume: 16, Issue:1

    Topics: Aneuploidy; Animals; Benomyl; Biotransformation; Carbamates; Cell Division; Cells, Cultured; Female;

1990
The feasibility of using Chinese hamsters as an animal model for aneuploidy.
    Environmental and molecular mutagenesis, 1990, Volume: 16, Issue:4

    Topics: Aneuploidy; Animals; Benzimidazoles; Bone Marrow; Carbamates; Cricetinae; Cricetulus; Cyclophosphami

1990
The detection of mitotic and meiotic chromosome gain in the yeast Saccharomyces cerevisiae: effects of methyl benzimidazol-2-yl carbamate, methyl methanesulfonate, ethyl methanesulfonate, dimethyl sulfoxide, propionitrile and cyclophosphamide monohydrate.
    Mutation research, 1990, Volume: 242, Issue:3

    Topics: Aneuploidy; Benzimidazoles; Carbamates; Chromosomes, Fungal; Cyclophosphamide; Dimethyl Sulfoxide; E

1990
The detection of mitotic and meiotic aneuploidy in yeast using a gene dosage selection system.
    Molecular & general genetics : MGG, 1988, Volume: 215, Issue:1

    Topics: Aneuploidy; Benzimidazoles; Carbamates; Genes, Fungal; Genetic Markers; Meiosis; Mitosis; Saccharomy

1988
Pattern and frequency of nondisjunction in oocytes from the Djungarian hamster are determined by the stage of first meiotic spindle inhibition.
    Chromosoma, 1988, Volume: 97, Issue:3

    Topics: Aneuploidy; Animals; Benzimidazoles; Carbamates; Chorionic Gonadotropin; Cricetinae; Female; Liver;

1988
Effects of chemical combinations on the induction of aneuploidy in Saccharomyces cerevisiae.
    Mutation research, 1987, Volume: 187, Issue:1

    Topics: Acetates; Acetone; Aneuploidy; Benzimidazoles; Butanones; Carbamates; Dimethyl Sulfoxide; Dimethylfo

1987
Analysis by BrUdR-labelling technique of induced aneuploidy in mammalian cells in culture.
    Mutation research, 1987, Volume: 177, Issue:2

    Topics: Aneuploidy; Animals; Benomyl; Bromodeoxyuridine; Carbamates; Cell Division; Cell Line; Cricetinae; D

1987