Page last updated: 2024-10-16

carbamates and Allergic Encephalomyelitis

carbamates has been researched along with Allergic Encephalomyelitis in 5 studies

Research Excerpts

ExcerptRelevanceReference
"PL mice with myelin basic protein on Days 0 and 2, and mice received twice daily oral dosing of SNJ 1945 from Day 9 until sacrificing (Day 26)."5.43Calpain inhibition reduces structural and functional impairment of retinal ganglion cells in experimental optic neuritis. ( Azuma, M; Banik, NL; Inoue, J; Ray, SK; Rohrer, B; Samantaray, S; Smith, AW; Wheless, L, 2016)
" Here, we show that oral dosing with SNJ-1945, a novel water-soluble calpain inhibitor, reduces experimental autoimmune encephalomyelitis clinical scores in vivo and has a two pronged effect via anti-inflammation and protection against neurodegeneration."5.40Effects of a novel orally administered calpain inhibitor SNJ-1945 on immunomodulation and neurodegeneration in a murine model of multiple sclerosis. ( Azuma, M; Banik, NL; Beeson, C; Haque, A; Inoue, J; Smith, A; Trager, N; Wallace Iv, G, 2014)
"PL mice with myelin basic protein on Days 0 and 2, and mice received twice daily oral dosing of SNJ 1945 from Day 9 until sacrificing (Day 26)."1.43Calpain inhibition reduces structural and functional impairment of retinal ganglion cells in experimental optic neuritis. ( Azuma, M; Banik, NL; Inoue, J; Ray, SK; Rohrer, B; Samantaray, S; Smith, AW; Wheless, L, 2016)
" Here, we show that oral dosing with SNJ-1945, a novel water-soluble calpain inhibitor, reduces experimental autoimmune encephalomyelitis clinical scores in vivo and has a two pronged effect via anti-inflammation and protection against neurodegeneration."1.40Effects of a novel orally administered calpain inhibitor SNJ-1945 on immunomodulation and neurodegeneration in a murine model of multiple sclerosis. ( Azuma, M; Banik, NL; Beeson, C; Haque, A; Inoue, J; Smith, A; Trager, N; Wallace Iv, G, 2014)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's5 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Manterola, A1
Bernal-Chico, A1
Cipriani, R1
Ruiz, A1
Pérez-Samartín, A1
Moreno-Rodríguez, M1
Hsu, KL1
Cravatt, BF1
Brown, JM1
Rodríguez-Puertas, R1
Matute, C1
Mato, S1
Trager, N1
Smith, A1
Wallace Iv, G1
Azuma, M2
Inoue, J2
Beeson, C1
Haque, A1
Banik, NL2
Rosenberger, TA1
Wen, J1
Ribeiro, R1
Tanaka, M1
Zhang, Y1
Smith, AW1
Rohrer, B1
Wheless, L1
Samantaray, S1
Ray, SK1

Other Studies

5 other studies available for carbamates and Allergic Encephalomyelitis

ArticleYear
Re-examining the potential of targeting ABHD6 in multiple sclerosis: Efficacy of systemic and peripherally restricted inhibitors in experimental autoimmune encephalomyelitis.
    Neuropharmacology, 2018, Volume: 141

    Topics: Animals; Benzoates; Biphenyl Compounds; Brain; Calcium; Carbamates; Cells, Cultured; Encephalomyelit

2018
Effects of a novel orally administered calpain inhibitor SNJ-1945 on immunomodulation and neurodegeneration in a murine model of multiple sclerosis.
    Journal of neurochemistry, 2014, Volume: 130, Issue:2

    Topics: Animals; Blotting, Western; Calpain; Carbamates; Cell Proliferation; Cell Separation; Cysteine Prote

2014
Targeting calpain-mediated proteolysis and peptide signaling as a strategy to reduce injury in multiple sclerosis.
    Journal of neurochemistry, 2014, Volume: 130, Issue:2

    Topics: Animals; Calpain; Carbamates; Cysteine Proteinase Inhibitors; Encephalomyelitis, Autoimmune, Experim

2014
Activation of CB2 receptor is required for the therapeutic effect of ABHD6 inhibition in experimental autoimmune encephalomyelitis.
    Neuropharmacology, 2015, Volume: 99

    Topics: Animals; Anti-Inflammatory Agents; Biphenyl Compounds; Carbamates; Encephalomyelitis, Autoimmune, Ex

2015
Calpain inhibition reduces structural and functional impairment of retinal ganglion cells in experimental optic neuritis.
    Journal of neurochemistry, 2016, Volume: 139, Issue:2

    Topics: Animals; Calpain; Carbamates; Cell Death; Electroretinography; Encephalomyelitis, Autoimmune, Experi

2016