carbamates has been researched along with Aging in 38 studies
Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Aging, a natural process of neurodegeneration, was associated with a reduction in Notch-1 signaling in rat cortex and hippocampus, and this was restored with chronic treatment with URB 597." | 3.78 | The endocannabinoid, anandamide, augments Notch-1 signaling in cultured cortical neurons exposed to amyloid-β and in the cortex of aged rats. ( Bowie, AG; Campbell, VA; Gowran, A; Keating, SE; Noonan, J; Tanveer, R, 2012) |
| "The changes in extracellular acetylcholine levels were investigated by microdialysis in the cortex and hippocampus of aging rats after administration of metrifonate (80 mg/kg), rivastigmine (0." | 3.71 | Effect of subchronic administration of metrifonate, rivastigmine and donepezil on brain acetylcholine in aged F344 rats. ( Bellucci, A; Casamenti, F; Costagli, C; Pepeu, G; Scali, C; Schmidt, B, 2002) |
| " The drug was generally safe and well tolerated." | 2.73 | Pharmacokinetics, safety, and tolerability of the new antiepileptic carisbamate in the elderly. ( Levy, R; Novak, G; Ragueneau-Majlessi, I; Solanki, B; Yao, C; Zannikos, P, 2008) |
| "Tacrine was the first cholinesterase inhibitor approved by regulatory agencies, followed by donepezil, rivastigmine and recently galantamine." | 2.41 | Clinical pharmacokinetics and pharmacodynamics of cholinesterase inhibitors. ( Jann, MW; Shirley, KL; Small, GW, 2002) |
| " Our results indicate that the neuromodulation facilitated by AEA can reduce the neuroimmune response induced by the chronic administration of alcohol beginning in adolescence in rats." | 1.51 | URB597 ameliorates the deleterious effects induced by binge alcohol consumption in adolescent rats. ( Bellozi, PMQ; Campos, AC; de Oliveira, ACP; Lima, IVA; Nakamura-Palacios, EM; Pelição, R; Rodrigues, LCM; Saliba, SW; Santos, MC; Teixeira, AL; Vieira, ÉLM, 2019) |
| "8% of patients treated with a combination of a sulfonylurea and insulin knew this side effect of the OAD." | 1.48 | Hypoglycemic side effects of sulfonylureas and repaglinide in ageing patients - knowledge and self-management. ( Harsch, IA; Kaestner, RH; Konturek, PC, 2018) |
| "Anandamide is an endocannabinoid involved in several physiological functions including neuroprotection." | 1.40 | Normal aging in rats and pathological aging in human Alzheimer's disease decrease FAAH activity: modulation by cannabinoid agonists. ( de Ceballos, ML; Giusto, NM; Martín-Moreno, AM; Pascual, AC; Pasquaré, SJ, 2014) |
| "Seizures were induced 30 min later using a chemoconvulsant (pentylenetetrazol, PTZ) model, which has been widely used to determine anticonvulsant efficacy of many other antiepileptic drugs in neonatal animals." | 1.38 | Anticonvulsant effect of retigabine during postnatal development in rats. ( Forcelli, PA; Gale, K; Kondratyev, A; Lakhkar, A; Soper, C, 2012) |
| " The best-fitting models were selected for the single-chemical dose-response data and used to develop a combined prediction model, which was then compared with the experimental mixture data." | 1.38 | Impact of chemical proportions on the acute neurotoxicity of a mixture of seven carbamates in preweanling and adult rats. ( Haber, LT; Hertzberg, RC; Moser, VC; Padilla, S; Simmons, JE, 2012) |
| " This may be explained by better bioavailability and/or by reduced stability of the circadian rhythmicity in elderly individuals." | 1.31 | The effect of rivastigmine on sleep in elderly healthy subjects. ( Berger, M; Braus, D; Gattaz, WF; Heuser, I; Riemann, D; Schredl, M; Weber, B, 2000) |
| "The four lenses from the renal failure patients were searched for evidence of carbamylation at lysyl or cysteinyl residues: carbamylation was not detected." | 1.29 | Glutathione adducts, not carbamylated lysines, are the major modification of lens alpha-crystallins from renal failure patients. ( Miesbauer, LR; Schwedler, J; Shun-Shin, GA; Smith, DL; Smith, JB; Sun, Y; Yang, Z; Zhou, X, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (26.32) | 18.7374 |
| 1990's | 5 (13.16) | 18.2507 |
| 2000's | 11 (28.95) | 29.6817 |
| 2010's | 11 (28.95) | 24.3611 |
| 2020's | 1 (2.63) | 2.80 |
| Authors | Studies |
|---|---|
| Yang, GX | 1 |
| Huang, Y | 1 |
| Zheng, LL | 1 |
| Zhang, L | 1 |
| Su, L | 1 |
| Wu, YH | 1 |
| Li, J | 1 |
| Zhou, LC | 1 |
| Huang, J | 1 |
| Tang, Y | 1 |
| Wang, R | 1 |
| Ma, L | 1 |
| Harsch, IA | 1 |
| Kaestner, RH | 1 |
| Konturek, PC | 1 |
| Bellozi, PMQ | 1 |
| Pelição, R | 1 |
| Santos, MC | 1 |
| Lima, IVA | 1 |
| Saliba, SW | 1 |
| Vieira, ÉLM | 1 |
| Campos, AC | 1 |
| Teixeira, AL | 1 |
| de Oliveira, ACP | 1 |
| Nakamura-Palacios, EM | 1 |
| Rodrigues, LCM | 1 |
| Pascual, AC | 1 |
| Martín-Moreno, AM | 1 |
| Giusto, NM | 1 |
| de Ceballos, ML | 1 |
| Pasquaré, SJ | 1 |
| Manduca, A | 1 |
| Morena, M | 1 |
| Campolongo, P | 1 |
| Servadio, M | 1 |
| Palmery, M | 1 |
| Trabace, L | 1 |
| Hill, MN | 1 |
| Vanderschuren, LJ | 1 |
| Cuomo, V | 1 |
| Trezza, V | 1 |
| López-Hoyos, M | 1 |
| Álvarez-Rodríguez, L | 1 |
| Mahler, M | 1 |
| Torices, S | 1 |
| Calvo-Alén, J | 1 |
| Villa, I | 1 |
| Seaman, A | 1 |
| Yee, A | 1 |
| Martínez-Taboada, V | 1 |
| Marco, EM | 1 |
| Rubino, T | 1 |
| Adriani, W | 1 |
| Viveros, MP | 1 |
| Parolaro, D | 1 |
| Laviola, G | 1 |
| Gutierrez, DB | 1 |
| Garland, D | 1 |
| Schey, KL | 1 |
| Forcelli, PA | 1 |
| Soper, C | 1 |
| Lakhkar, A | 1 |
| Gale, K | 1 |
| Kondratyev, A | 1 |
| Murphy, N | 1 |
| Cowley, TR | 1 |
| Blau, CW | 1 |
| Dempsey, CN | 1 |
| Noonan, J | 2 |
| Gowran, A | 2 |
| Tanveer, R | 2 |
| Olango, WM | 1 |
| Finn, DP | 1 |
| Campbell, VA | 2 |
| Lynch, MA | 1 |
| Moser, VC | 1 |
| Padilla, S | 1 |
| Simmons, JE | 1 |
| Haber, LT | 1 |
| Hertzberg, RC | 1 |
| Keating, SE | 1 |
| Bowie, AG | 1 |
| Perrin, S | 1 |
| Cremer, J | 1 |
| Faucher, O | 1 |
| Reynes, J | 1 |
| Dellamonica, P | 1 |
| Micallef, J | 1 |
| Solas, C | 1 |
| Lacarelle, B | 1 |
| Stretti, C | 1 |
| Kaspi, E | 1 |
| Robaglia-Schlupp, A | 1 |
| Nicolino-Brunet, C | 1 |
| Tamalet, CN | 1 |
| Tamalet, C | 1 |
| Lévy, N | 1 |
| Poizot-Martin, I | 1 |
| Cau, P | 1 |
| Roll, P | 1 |
| Scali, C | 1 |
| Casamenti, F | 1 |
| Bellucci, A | 1 |
| Costagli, C | 1 |
| Schmidt, B | 1 |
| Pepeu, G | 1 |
| Jann, MW | 1 |
| Shirley, KL | 1 |
| Small, GW | 1 |
| Hermann, R | 1 |
| Ferron, GM | 1 |
| Erb, K | 1 |
| Knebel, N | 1 |
| Ruus, P | 1 |
| Paul, J | 1 |
| Richards, L | 1 |
| Cnota, HP | 1 |
| Troy, S | 1 |
| SIMONSON, E | 1 |
| Abe, Y | 1 |
| Aoyagi, A | 1 |
| Hara, T | 1 |
| Abe, K | 1 |
| Yamazaki, R | 1 |
| Kumagae, Y | 1 |
| Naruto, S | 1 |
| Koyama, K | 1 |
| Marumoto, S | 1 |
| Tago, K | 1 |
| Toda, N | 1 |
| Takami, K | 1 |
| Yamada, N | 1 |
| Ori, M | 1 |
| Kogen, H | 1 |
| Kaneko, T | 1 |
| Andersen, TH | 1 |
| Tjørnhøj, R | 1 |
| Wollenberger, L | 1 |
| Slothuus, T | 1 |
| Baun, A | 1 |
| Chandrasekara, LW | 1 |
| Pathiratne, A | 1 |
| Levy, R | 1 |
| Ragueneau-Majlessi, I | 1 |
| Solanki, B | 1 |
| Zannikos, P | 1 |
| Yao, C | 1 |
| Novak, G | 1 |
| Mazarati, A | 1 |
| Wu, J | 1 |
| Shin, D | 1 |
| Kwon, YS | 1 |
| Sankar, R | 1 |
| Smith, JB | 1 |
| Shun-Shin, GA | 1 |
| Sun, Y | 1 |
| Miesbauer, LR | 1 |
| Yang, Z | 2 |
| Zhou, X | 1 |
| Schwedler, J | 1 |
| Smith, DL | 1 |
| Fishwick, SK | 1 |
| Shore, RF | 1 |
| Turk, A | 1 |
| Sparks, TH | 1 |
| Ohara, T | 1 |
| Fukaya, H | 1 |
| Itanaka, K | 1 |
| Seno, N | 1 |
| Schredl, M | 1 |
| Weber, B | 1 |
| Braus, D | 1 |
| Gattaz, WF | 1 |
| Berger, M | 1 |
| Riemann, D | 1 |
| Heuser, I | 1 |
| Culy, CR | 1 |
| Jarvis, B | 1 |
| Rosen, MR | 1 |
| Reder, RF | 1 |
| Hordof, AJ | 1 |
| Davies, M | 1 |
| Danilo, P | 1 |
| Belzunces, LP | 1 |
| Colin, ME | 1 |
| Saito, K | 1 |
| Kaneko, H | 1 |
| Sato, K | 1 |
| Yoshitake, A | 1 |
| Yamada, H | 1 |
| Ratner, S | 1 |
| Hansen, LG | 1 |
| Hodgson, E | 1 |
| Pieraggi, MT | 1 |
| Julian, M | 1 |
| Bouissou, H | 1 |
| Forman, HJ | 1 |
| Grisolia, S | 1 |
| Majeron, MA | 1 |
| Toselli, E | 1 |
| Georghious, GP | 1 |
| Nery, R | 1 |
| Maresh, CG | 1 |
| Kwan, TH | 1 |
| Kalman, SM | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Accelerated Aging, HIV Infection, Antiretroviral Therapies[NCT01038999] | 200 participants (Anticipated) | Observational | 2009-04-30 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 reviews available for carbamates and Aging
| Article | Year |
|---|---|
Clinical pharmacokinetics and pharmacodynamics of cholinesterase inhibitors.
Topics: Aging; Alzheimer Disease; Biological Availability; Carbamates; Cholinesterase Inhibitors; Donepezil; | 2002 |
EFFECT OF AGE ON THE CARDIOVASCULAR SYSTEM IN RECENT RUSSIAN RESEARCH.
Topics: Aging; Arteriosclerosis; Carbamates; Cardiovascular System; Electrocardiography; Electrophysiology; | 1964 |
Repaglinide: a review of its therapeutic use in type 2 diabetes mellitus.
Topics: Administration, Oral; Adult; Aged; Aging; Animals; Biological Availability; Blood Glucose; Carbamate | 2001 |
Enzymes of arginine and urea synthesis.
Topics: Aging; Amino Acid Metabolism, Inborn Errors; Animals; Arginase; Arginine; Binding Sites; Carbamates; | 1973 |
3 trials available for carbamates and Aging
| Article | Year |
|---|---|
HIV protease inhibitors do not cause the accumulation of prelamin A in PBMCs from patients receiving first line therapy: the ANRS EP45 "aging" study.
Topics: Aging; Atazanavir Sulfate; Carbamates; Cross-Sectional Studies; Female; Furans; HIV Infections; HIV | 2012 |
Effects of age and sex on the disposition of retigabine.
Topics: Adult; Aged; Aged, 80 and over; Aging; Anticonvulsants; Area Under Curve; Carbamates; Creatinine; Fe | 2003 |
Pharmacokinetics, safety, and tolerability of the new antiepileptic carisbamate in the elderly.
Topics: Administration, Oral; Adult; Age Factors; Aged; Aging; Anticonvulsants; Area Under Curve; Carbamates | 2008 |
31 other studies available for carbamates and Aging
| Article | Year |
|---|---|
Design, synthesis and evaluation of diosgenin carbamate derivatives as multitarget anti-Alzheimer's disease agents.
Topics: Aging; Alzheimer Disease; Amyloid beta-Peptides; Animals; Anti-Inflammatory Agents, Non-Steroidal; A | 2020 |
Hypoglycemic side effects of sulfonylureas and repaglinide in ageing patients - knowledge and self-management.
Topics: Aged; Aged, 80 and over; Aging; Carbamates; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Fe | 2018 |
URB597 ameliorates the deleterious effects induced by binge alcohol consumption in adolescent rats.
Topics: Aging; Amidohydrolases; Animals; Benzamides; Binge Drinking; Brain; Brain-Derived Neurotrophic Facto | 2019 |
Normal aging in rats and pathological aging in human Alzheimer's disease decrease FAAH activity: modulation by cannabinoid agonists.
Topics: Aged; Aged, 80 and over; Aging; Alzheimer Disease; Amidohydrolases; Amyloid beta-Peptides; Animals; | 2014 |
Distinct roles of the endocannabinoids anandamide and 2-arachidonoylglycerol in social behavior and emotionality at different developmental ages in rats.
Topics: Aging; Animals; Anxiety; Arachidonic Acids; Brain; Cannabinoid Receptor Modulators; Carbamates; Endo | 2015 |
Anti-carbamylated protein antibodies in patients with ageing associated inflammatory chronic disorders.
Topics: Aged; Aged, 80 and over; Aging; Arthritis, Rheumatoid; Autoantibodies; Biomarkers; Blood Proteins; C | 2016 |
Long-term consequences of URB597 administration during adolescence on cannabinoid CB1 receptor binding in brain areas.
Topics: Aging; Analysis of Variance; Animals; Arachidonic Acids; Autoradiography; Benzamides; Brain; Carbama | 2009 |
Spatial analysis of human lens aquaporin-0 post-translational modifications by MALDI mass spectrometry tissue profiling.
Topics: Acetylation; Adult; Age Factors; Aged; Aging; Aquaporins; Carbamates; Child; Chromatography, Liquid; | 2011 |
Anticonvulsant effect of retigabine during postnatal development in rats.
Topics: Aging; Animals; Animals, Newborn; Anticonvulsants; Carbamates; Convulsants; Dose-Response Relationsh | 2012 |
The fatty acid amide hydrolase inhibitor URB597 exerts anti-inflammatory effects in hippocampus of aged rats and restores an age-related deficit in long-term potentiation.
Topics: Aging; Amidohydrolases; Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzamides; Carbamates; Hi | 2012 |
Impact of chemical proportions on the acute neurotoxicity of a mixture of seven carbamates in preweanling and adult rats.
Topics: Aging; Animals; Brain; Carbamates; Cholinesterase Inhibitors; Cholinesterases; Complex Mixtures; Dos | 2012 |
The endocannabinoid, anandamide, augments Notch-1 signaling in cultured cortical neurons exposed to amyloid-β and in the cortex of aged rats.
Topics: Aging; Alzheimer Disease; Amyloid beta-Peptides; Amyloid Precursor Protein Secretases; Animals; Arac | 2012 |
Effect of subchronic administration of metrifonate, rivastigmine and donepezil on brain acetylcholine in aged F344 rats.
Topics: Acetylcholine; Aging; Animals; Body Weight; Brain; Carbamates; Cerebral Cortex; Cholinesterase Inhib | 2002 |
Pharmacological characterization of RS-1259, an orally active dual inhibitor of acetylcholinesterase and serotonin transporter, in rodents: possible treatment of Alzheimer's disease.
Topics: Acetylcholinesterase; Administration, Oral; Aging; Alzheimer Disease; Animals; Carbamates; Carrier P | 2003 |
Acute and chronic effects of pulse exposure of Daphnia magna to dimethoate and pirimicarb.
Topics: Aging; Animals; Behavior, Animal; Body Size; Body Weight; Carbamates; Daphnia; Dimethoate; Pyrimidin | 2006 |
Body size-related differences in the inhibition of brain acetylcholinesterase activity in juvenile Nile tilapia (Oreochromis niloticus) by chlorpyrifos and carbosulfan.
Topics: Acetylcholinesterase; Aging; Animals; Biomarkers; Body Size; Brain; Carbamates; Chlorpyrifos; Cholin | 2007 |
Antiepileptogenic and antiictogenic effects of retigabine under conditions of rapid kindling: an ontogenic study.
Topics: Aging; Animals; Animals, Newborn; Anticonvulsants; Behavior, Animal; Carbamates; Disease Models, Ani | 2008 |
Glutathione adducts, not carbamylated lysines, are the major modification of lens alpha-crystallins from renal failure patients.
Topics: Aged; Aged, 80 and over; Aging; Carbamates; Crystallins; Female; Glutathione; Guanidine; Guanidines; | 1995 |
Variation of brain and serum cholinesterase activity with age in wild small mammals.
Topics: Aging; Animals; Animals, Wild; Arvicolinae; Biomarkers; Brain; Carbamates; Cholinesterase Inhibitors | 1996 |
Ameliorating effects of SDZ ENA 713 on age-associated decreases in learning performance and brain choline acetyltransferase activity in rats.
Topics: Aging; Animals; Biomarkers; Brain; Carbamates; Choline O-Acetyltransferase; Cholinesterase Inhibitor | 1997 |
The effect of rivastigmine on sleep in elderly healthy subjects.
Topics: Aged; Aging; Analysis of Variance; Carbamates; Cholinesterase Inhibitors; Female; Humans; Male; Midd | 2000 |
Age-related changes in Purkinje fiber action potentials of adult dogs.
Topics: Action Potentials; Aging; Animals; Carbamates; Dogs; Electrocardiography; Female; Heart Conduction S | 1978 |
Differential response of Apis mellifera acetylcholinesterase towards pirimicarb.
Topics: Acetylcholinesterase; Aging; Animals; Bees; Carbamates; Cholinesterase Inhibitors; Chromatography, A | 1991 |
Age-related changes in metabolism of diethofencarb: relationship between metabolism in rat and hepatic drug-metabolizing enzyme activities.
Topics: Aging; Animals; Carbamates; Carbon Radioisotopes; Liver; Male; Phenylcarbamates; Rats; Rats, Inbred | 1991 |
Biochemical characteristics of insect microsomes. N- and O-demethylation.
Topics: Abdomen; Age Factors; Aging; Aniline Compounds; Animals; Anisoles; Carbamates; Cattle; Cell Nucleus; | 1971 |
Aortic lathyrism: ultrastructural study of lesions in the aortic wall and the protective effect of pyridinol carbamate.
Topics: Aging; Aminopropionitrile; Animals; Aorta; Arteriosclerosis; Carbamates; Dietary Fats; Histiocytes; | 1974 |
The effect of cyanate, carbamyl phosphate and growth on the glutamine dependent carbamyl phosphate synthetase from rat spleen and brain.
Topics: Aging; Animals; Body Weight; Brain; Carbamates; Carbamoyl-Phosphate Synthase (Glutamine-Hydrolyzing) | 1974 |
[Clinical experience with a new tranquilizing agent: tybamate].
Topics: Aging; Anxiety Disorders; Carbamates; Depression; Evaluation Studies as Topic; Humans; Psychotic Dis | 1969 |
Considerations on the relationship of larval and adult tolerance to insecticides in mosquitoes.
Topics: Aging; Animals; Anopheles; Carbamates; Culex; Hydrocarbons, Halogenated; Insecticide Resistance; Ins | 1970 |
Some aspects of the metabolism of urethane and N-hydroxyurethane in rodents.
Topics: Aging; Animals; Animals, Newborn; Carbamates; Chloromercuribenzoates; Cyanides; Depression, Chemical | 1968 |
Carbamyl phosphate synthetase in the chick.
Topics: Aging; Animals; Carbamates; Carbon Isotopes; Chick Embryo; Chickens; Chromatography, Thin Layer; Cit | 1969 |