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carbachol and Tremor

carbachol has been researched along with Tremor in 25 studies

Carbachol: A slowly hydrolyzed CHOLINERGIC AGONIST that acts at both MUSCARINIC RECEPTORS and NICOTINIC RECEPTORS.

Tremor: Cyclical movement of a body part that can represent either a physiologic process or a manifestation of disease. Intention or action tremor, a common manifestation of CEREBELLAR DISEASES, is aggravated by movement. In contrast, resting tremor is maximal when there is no attempt at voluntary movement, and occurs as a relatively frequent manifestation of PARKINSON DISEASE.

Research Excerpts

ExcerptRelevanceReference
"A series of tertiary 3- and 4-haloalkylamines related to the muscarinic agent oxotremorine was synthesized."7.67Tertiary 3- and 4-haloalkylamine analogues of oxotremorine as prodrugs of potent muscarinic agonists. ( Jenden, DJ; Ringdahl, B; Roch, M, 1988)
"The enantiomers of three 5-methyl-2-pyrrolidone analogues of the muscarinic agent oxotremorine (1) were synthesized."7.67Stereoselectivity of muscarinic receptors in vivo and in vitro for oxotremorine analogues. N-[4-(tertiary amino)-2-butynyl]-5-methyl-2-pyrrolidones. ( Amstutz, R; Jenden, DJ; Karlén, B; Ringdahl, B; Roch, M, 1985)
"Tremor produced by intracerebral injection of carbachol."7.65[Tremor following intracerebral carbachol injection. 1.Carbachol sensitivity of various brain structures]. ( Freyer, M; Schade, C; Staib, AH; Westermann, KH, 1975)
"A series of tertiary 3- and 4-haloalkylamines related to the muscarinic agent oxotremorine was synthesized."3.67Tertiary 3- and 4-haloalkylamine analogues of oxotremorine as prodrugs of potent muscarinic agonists. ( Jenden, DJ; Ringdahl, B; Roch, M, 1988)
"The enantiomers of three 5-methyl-2-pyrrolidone analogues of the muscarinic agent oxotremorine (1) were synthesized."3.67Stereoselectivity of muscarinic receptors in vivo and in vitro for oxotremorine analogues. N-[4-(tertiary amino)-2-butynyl]-5-methyl-2-pyrrolidones. ( Amstutz, R; Jenden, DJ; Karlén, B; Ringdahl, B; Roch, M, 1985)
"The effect of calcium chloride injected into the cerebral ventricles of group-housed unanaesthetized cats upon vocalization (rage, hissing and snarling), fighting (attack with paws and claws, defense with paws and claws and biting), mydriasis, tremor and clonic-tonic convulsions produced by carbachol and eserine injected similarly was investigated."3.66Effect of calcium chloride on gross behavioural changes produced by carbachol and eserine in cats. ( Beleslin, DB; Krstić, SK; Samardzic, R; Strbac, M, 1982)
"Tremor produced by intracerebral injection of carbachol."3.65[Tremor following intracerebral carbachol injection. 1.Carbachol sensitivity of various brain structures]. ( Freyer, M; Schade, C; Staib, AH; Westermann, KH, 1975)
" administration, for eight days, of the cholinesterase inhibitor disulfoton to rats produced mild to moderate signs of intoxication (tremors, incontinence and diarrhoea) but no deaths."3.65Response of the rat ileum, uterus and vas deferens to carbachol and acetylcholine following repeated daily administration of a cholinesterase inhibitor. ( Foley, DJ; McPhillips, JJ, 1973)
" Carbachol or oxotremorine injected in small doses intracerebroventricularly into conscious mice caused hypothermia, gross tremor and a variety of parasympathomimetic effects including lachrymation and salivation."3.65Investigation of central cholinergic mechanisms in the conscious mouse. ( Ankier, SI; Brittain, RT; Jack, D, 1971)

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-199023 (92.00)18.7374
1990's1 (4.00)18.2507
2000's1 (4.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lundkvist, JR1
Ringdahl, B3
Hacksell, U1
Roch, M2
Jenden, DJ4
Bromidge, SM1
Brown, F1
Cassidy, F1
Clark, MS1
Dabbs, S1
Hadley, MS1
Hawkins, J1
Loudon, JM1
Naylor, CB1
Orlek, BS1
Riley, GJ1
BOSKOVIC, B1
CATOVIC, S1
STERN, P1
Beleslin, DB1
Samardzic, R1
Krstić, SK1
Strbac, M1
Bymaster, FP1
Carter, PA1
Zhang, L1
Falcone, JF1
Stengel, PW1
Cohen, ML1
Shannon, HE1
Gomeza, J1
Wess, J1
Felder, CC1
Buckley, GA1
Heading, CE1
Moradian, MH1
Matthews, RT1
Chiou, CY1
Westermann, KH1
Freyer, M1
Schade, C1
Staib, AH1
Amstutz, R1
Karlén, B1
Connor, JD2
Rossi, GV4
Baker, WW5
Molnár, J1
György, L1
Pfeifer, KA1
Nádor, K1
Murphey, DL2
Dill, RE4
Foley, DJ1
McPhillips, JJ1
Lalley, PM2
Ankier, SI1
Brittain, RT1
Jack, D1
Szekely, EG1
Zivanovic, D1
Nickey, WM1
Little, MD2
Sheu, YS1
George, R2
Haslett, WL1

Other Studies

25 other studies available for carbachol and Tremor

ArticleYear
Conformationally restricted analogues of the muscarinic agent N-methyl-N-(1-methyl-4-pyrrolidino-2-butynyl)acetamide.
    Journal of medicinal chemistry, 1989, Volume: 32, Issue:4

    Topics: Animals; Biological Assay; Cerebral Cortex; Chemical Phenomena; Chemistry; Guinea Pigs; Ileum; Mice;

1989
Tertiary 3- and 4-haloalkylamine analogues of oxotremorine as prodrugs of potent muscarinic agonists.
    Journal of medicinal chemistry, 1988, Volume: 31, Issue:1

    Topics: Analgesia; Animals; Guinea Pigs; Ileum; In Vitro Techniques; Indicators and Reagents; Kinetics; Magn

1988
Design of [R-(Z)]-(+)-alpha-(methoxyimino)-1-azabicyclo[2.2.2]octane-3-acetonitri le (SB 202026), a functionally selective azabicyclic muscarinic M1 agonist incorporating the N-methoxy imidoyl nitrile group as a novel ester bioisostere.
    Journal of medicinal chemistry, 1997, Dec-19, Volume: 40, Issue:26

    Topics: Alzheimer Disease; Animals; Binding Sites; Blood Pressure; Brain; CHO Cells; Cricetinae; Electroence

1997
THE SITE OF ACTION OF ANTIPARKINSONISM DRUGS.
    International journal of neuropharmacology, 1964, Volume: 3

    Topics: Acetylcholine; Animals; Anterior Horn Cells; Anticonvulsants; Atropine; Carbachol; Cell Biology; Het

1964
Effect of calcium chloride on gross behavioural changes produced by carbachol and eserine in cats.
    Acta physiologica Academiae Scientiarum Hungaricae, 1982, Volume: 60, Issue:1-2

    Topics: Aggression; Animals; Autonomic Nervous System; Behavior, Animal; Calcium Chloride; Carbachol; Cats;

1982
Investigations into the physiological role of muscarinic M2 and M4 muscarinic and M4 receptor subtypes using receptor knockout mice.
    Life sciences, 2001, Apr-27, Volume: 68, Issue:22-23

    Topics: Animals; Carbachol; Cerebral Cortex; Heart; Heart Rate; Humans; Hypothermia; Male; Mice; Mice, Knock

2001
Tolerance to neostigmine in rodents and its prevention by cycloheximide treatment.
    The Journal of pharmacy and pharmacology, 1978, Volume: 30, Issue:5

    Topics: Animals; Atropine Derivatives; Carbachol; Cycloheximide; Drug Tolerance; Female; Lethal Dose 50; Mal

1978
Effects of acute and chronic injections of carbachol in the rat caudate nucleus.
    Neuropharmacology, 1979, Volume: 18, Issue:3

    Topics: Animals; Carbachol; Caudate Nucleus; Drug Tolerance; Injections; Male; Rats; Time Factors; Tremor

1979
[Tremor following intracerebral carbachol injection. 1.Carbachol sensitivity of various brain structures].
    Acta biologica et medica Germanica, 1975, Volume: 34, Issue:3

    Topics: Animals; Brain; Brain Mapping; Carbachol; Cerebral Cortex; Female; Injections, Intraventricular; Rat

1975
Stereoselectivity of muscarinic receptors in vivo and in vitro for oxotremorine analogues. N-[4-(tertiary amino)-2-butynyl]-5-methyl-2-pyrrolidones.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:12

    Topics: Abdominal Muscles; Animals; Atropine; Carbachol; Chemical Phenomena; Chemistry; Guinea Pigs; Ileum;

1985
Antagonism of intracaudate carbachol tremor by local injections of catecholamines.
    The Journal of pharmacology and experimental therapeutics, 1967, Volume: 155, Issue:3

    Topics: Adenosine Triphosphate; Animals; Brain; Carbachol; Cats; Chlorpromazine; Dopamine; Electrophysiology

1967
Tremorigenic and convulsant actions of intracerebrally administered vegetative poisons in the mouse.
    Acta physiologica Academiae Scientiarum Hungaricae, 1967, Volume: 31, Issue:3

    Topics: Acetylcholine; Animals; Autonomic Nervous System; Carbachol; Central Nervous System Stimulants; Hist

1967
Excitatory responses following intracaudate injection of N-methyl-dl-aspartic acid.
    Archives internationales de pharmacodynamie et de therapie, 1972, Volume: 196, Issue:2

    Topics: Aggression; Animals; Arousal; Aspartic Acid; Carbachol; Cats; Caudate Nucleus; Humans; Male; Methyla

1972
Dentatectomy: absence of effects on dyskinesias arizing from chemical stimulation of the striatum in rats.
    Experientia, 1972, Jan-15, Volume: 28, Issue:1

    Topics: Animals; Basal Ganglia Diseases; Carbachol; Cerebellar Nuclei; Corpus Striatum; Male; Movement Disor

1972
Chemical stimulation of discrete brain loci as a method of producing dyskinesia models in primates.
    Experimental neurology, 1972, Volume: 34, Issue:2

    Topics: Animals; Basal Ganglia; Carbachol; Caudate Nucleus; Chorea; Disease Models, Animal; Extrapyramidal T

1972
Response of the rat ileum, uterus and vas deferens to carbachol and acetylcholine following repeated daily administration of a cholinesterase inhibitor.
    British journal of pharmacology, 1973, Volume: 48, Issue:3

    Topics: Acetylcholine; Animals; Carbachol; Cholinesterases; Diarrhea; Disulfoton; Drug Interactions; Female;

1973
Characteristics of tremor in cats following injections of carbachol into the caudate nucleus.
    Experimental neurology, 1966, Volume: 14, Issue:3

    Topics: Animals; Carbachol; Cats; Caudate Nucleus; Male; Tremor

1966
Alterations in tremor regulation after intracaudate injections of calcium ions or disodium edetate.
    Neuropharmacology, 1971, Volume: 10, Issue:5

    Topics: Animals; Calcium; Carbachol; Cats; Caudate Nucleus; Dopamine; Edetic Acid; Magnesium; Membrane Poten

1971
Analysis of local cholinergic tremor mechanisms following selective neurochemical lesions.
    Experimental neurology, 1970, Volume: 27, Issue:2

    Topics: Acetylcholine; Animals; Basal Ganglia; Brain; Carbachol; Cats; Cholinesterase Inhibitors; Disease Mo

1970
Investigation of central cholinergic mechanisms in the conscious mouse.
    British journal of pharmacology, 1971, Volume: 42, Issue:1

    Topics: Acetylcholine; Amphetamine; Animals; Antidepressive Agents; Atropine; Brain; Carbachol; Cerebral Ven

1971
Influence of the pyriform-amygdaloid region upon the tremor elicited by stimulation of the reticular formation.
    Confinia neurologica, 1967, Volume: 29, Issue:2

    Topics: Amygdala; Animals; Carbachol; Cats; Caudate Nucleus; Cerebral Cortex; Computers; Depression, Chemica

1967
Dyskinesia in rats following chemical stimulation of the neostriatum.
    Texas reports on biology and medicine, 1968,Spring, Volume: 26, Issue:1

    Topics: Animals; Carbachol; Dopamine; Extrapyramidal Tracts; Male; Motor Activity; Movement Disorders; Norep

1968
Tremorogenesis: evidence for cholinergic circuits in the brain.
    Proceedings of the Western Pharmacology Society, 1968, Volume: 11

    Topics: Animals; Atropine; Brain; Carbachol; Cats; Female; Male; Tremor

1968
Mescaline and other o-methylated beta-phenylethylamines: intrastriatal induction of tremor in rats.
    Brain research, 1969, Volume: 13, Issue:2

    Topics: Animals; Carbachol; Dopamine; Mescaline; Motor Activity; Phenethylamines; Rats; Tremor; Tyramine

1969
The production of tremor by cholinergic drugs: central sites of action.
    International journal of neuropharmacology, 1966, Volume: 5, Issue:1

    Topics: Animals; Atropine; Brain; Carbachol; Cats; Female; Male; Rats; Tremor; Tremorine

1966