carbachol has been researched along with Sicca Syndrome in 29 studies
Carbachol: A slowly hydrolyzed CHOLINERGIC AGONIST that acts at both MUSCARINIC RECEPTORS and NICOTINIC RECEPTORS.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The effect of SS or normal immunoglobulin G (IgG) on smooth muscle (SM) motility was assessed by comparing the amplitude of carbachol (CCh) or electrical field stimulation (EFS) - induced muscle contraction before and after IgG application." | 3.79 | The inhibitory effects of antimuscarinic autoantibodies in the sera of primary Sjogren syndrome patients on the gastrointestinal motility. ( Jackson, MW; Park, K; Park, S, 2013) |
| " Peptides corresponding to the second extracellular loop of the M3R were used as immunogens in rabbits, and antisera were tested for inhibition of carbachol-evoked colon smooth muscle contraction in parallel with immunoglobulin G from a patient with SS." | 3.72 | Antibodies raised against the second extracellular loop of the human muscarinic M3 receptor mimic functional autoantibodies in Sjögren's syndrome. ( Cavill, D; Gordon, TP; Waterman, SA, 2004) |
| "Carbachol (CCh) was found to consistently increase intracellular calcium concentration ([Ca(2+) ](i) ) and activate K(+) current in HSG cells." | 1.38 | Autoantibodies in Sjögren's syndrome patients acutely inhibit muscarinic receptor function. ( Choi, SY; Hwang, SM; Jin, M; Kho, HS; Kim, B; Koo, NY; Park, K; Song, YW, 2012) |
| "Carbachol was synthesized with an active choline group and was conjugated with an siRNA that targets caspase 3." | 1.37 | A secretagogue-small interfering RNA conjugate confers resistance to cytotoxicity in a cell model of Sjögren's syndrome. ( Cha, S; Chan, EK; Gauna, AE; Grichtchenko, II; Pauley, KM, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (3.45) | 18.7374 |
| 1990's | 2 (6.90) | 18.2507 |
| 2000's | 12 (41.38) | 29.6817 |
| 2010's | 12 (41.38) | 24.3611 |
| 2020's | 2 (6.90) | 2.80 |
| Authors | Studies |
|---|---|
| Fu, R | 1 |
| Edman, MC | 2 |
| Hamm-Alvarez, SF | 2 |
| Loy, F | 1 |
| Isola, M | 1 |
| Masala, C | 1 |
| Isola, R | 1 |
| Kurien, BT | 1 |
| Dsouza, A | 1 |
| Igoe, A | 1 |
| Lee, YJ | 1 |
| Maier-Moore, JS | 1 |
| Gordon, T | 1 |
| Jackson, M | 1 |
| Scofield, RH | 1 |
| Park, K | 7 |
| Park, S | 1 |
| Jackson, MW | 3 |
| Enger, TB | 1 |
| Aure, MH | 1 |
| Jensen, JL | 1 |
| Galtung, HK | 1 |
| Teos, LY | 1 |
| Zhang, Y | 1 |
| Cotrim, AP | 1 |
| Swaim, W | 1 |
| Won, JH | 1 |
| Ambrus, J | 1 |
| Shen, L | 1 |
| Bebris, L | 1 |
| Grisius, M | 1 |
| Jang, SI | 1 |
| Yule, DI | 1 |
| Ambudkar, IS | 1 |
| Alevizos, I | 1 |
| Meng, Z | 1 |
| Hsueh, PY | 1 |
| Chen, CY | 1 |
| Klinngam, W | 1 |
| Tolmachova, T | 1 |
| Okamoto, CT | 2 |
| Seo, J | 1 |
| Koo, NY | 3 |
| Choi, WY | 1 |
| Kang, JA | 1 |
| Min, JH | 1 |
| Jo, SH | 1 |
| Lee, SJ | 3 |
| Oh, SB | 3 |
| Kim, JS | 3 |
| Lee, JH | 3 |
| Choi, SY | 4 |
| Haberberger, RV | 1 |
| Gordon, TP | 5 |
| Pauley, KM | 2 |
| Gauna, AE | 2 |
| Grichtchenko, II | 1 |
| Chan, EK | 1 |
| Cha, S | 4 |
| Jin, M | 2 |
| Hwang, SM | 3 |
| Kim, B | 1 |
| Kho, HS | 1 |
| Song, YW | 4 |
| Davies, AJ | 1 |
| Shin, Y | 1 |
| Bae, JS | 1 |
| Lee, EB | 3 |
| Kajiya, M | 1 |
| Ichimonji, I | 1 |
| Min, C | 1 |
| Zhu, T | 1 |
| Jin, JO | 1 |
| Yu, Q | 1 |
| Almazrooa, SA | 1 |
| Kawai, T | 2 |
| Lee, BH | 1 |
| Perez, G | 1 |
| Park, YJ | 1 |
| Cavill, D | 2 |
| Waterman, SA | 4 |
| Li, J | 2 |
| Ha, YM | 1 |
| Kü, NY | 1 |
| Wang, F | 1 |
| Maughan, V | 1 |
| Smith, AJ | 1 |
| Singson, E | 1 |
| Cornelius, J | 1 |
| Yagna, JP | 1 |
| Knot, HJ | 1 |
| Peck, AB | 1 |
| Cox, SW | 1 |
| Ebersole, LE | 1 |
| Carpenter, GH | 1 |
| Proctor, GB | 1 |
| Bacman, S | 1 |
| Sterin-Borda, L | 1 |
| Camusso, JJ | 1 |
| Arana, R | 1 |
| Hubscher, O | 1 |
| Borda, E | 1 |
| Yang, T | 1 |
| Zeng, H | 1 |
| Zhang, J | 1 |
| Warren, DW | 1 |
| Wood, RL | 1 |
| Bachmann, M | 1 |
| Mircheff, AK | 1 |
| Kovács, L | 1 |
| Török, T | 1 |
| Bari, F | 1 |
| Kéri, Z | 1 |
| Kovács, A | 1 |
| Makula, E | 1 |
| Pokorny, G | 1 |
| Rischmueller, M | 2 |
| Dawson, LJ | 1 |
| Christmas, SE | 1 |
| Smith, PM | 1 |
| Liu, XB | 1 |
| Masago, R | 1 |
| Kong, L | 1 |
| Zhang, BX | 1 |
| Masago, S | 1 |
| Vela-Roch, N | 1 |
| Katz, MS | 1 |
| Yeh, CK | 1 |
| Zhang, GH | 1 |
| Talal, N | 1 |
| Dang, H | 1 |
| Paranyuk, Y | 1 |
| Claros, N | 1 |
| Birzgalis, A | 1 |
| Moore, LC | 1 |
| Brink, PR | 1 |
| Walcott, B | 1 |
| Bolstad, AI | 1 |
| Jonsson, R | 1 |
| Gelinsky, P | 1 |
1 review available for carbachol and Sicca Syndrome
| Article | Year |
|---|---|
Autoantibodies in primary Sjögren's syndrome: new insights into mechanisms of autoantibody diversification and disease pathogenesis.
Topics: Animals; Antibodies, Antinuclear; Antibody Specificity; Autoantibodies; Carbachol; Endoplasmic Retic | 2001 |
28 other studies available for carbachol and Sicca Syndrome
| Article | Year |
|---|---|
Rab27a Contributes to Cathepsin S Secretion in Lacrimal Gland Acinar Cells.
Topics: Acinar Cells; Animals; Carbachol; Cathepsins; Cells, Cultured; Disease Models, Animal; Endosomes; La | 2021 |
Reactivity of human labial glands in response to cevimeline treatment.
Topics: Carbachol; Humans; Lip; Quinuclidines; Salivary Glands; Sjogren's Syndrome; Thiophenes | 2021 |
Immunization with 60 kD Ro peptide produces different stages of preclinical autoimmunity in a Sjögren's syndrome model among multiple strains of inbred mice.
Topics: Amino Acid Sequence; Animals; Antibodies, Antinuclear; Autoantigens; Autoimmunity; Carbachol; Diseas | 2013 |
The inhibitory effects of antimuscarinic autoantibodies in the sera of primary Sjogren syndrome patients on the gastrointestinal motility.
Topics: Animals; Autoantibodies; Carbachol; Cholinergic Agonists; Colon; Diamines; Dose-Response Relationshi | 2013 |
Calcium signaling and cell volume regulation are altered in Sjögren's Syndrome.
Topics: Adult; Aged; Aged, 80 and over; Aquaporin 1; Aquaporin 3; Aquaporin 5; Aquaporins; Calcium Signaling | 2014 |
IP3R deficit underlies loss of salivary fluid secretion in Sjögren's Syndrome.
Topics: Acinar Cells; Animals; Calcium; Calcium Signaling; Carbachol; Case-Control Studies; Cell Size; Cells | 2015 |
Imbalanced Rab3D versus Rab27 increases cathepsin S secretion from lacrimal acini in a mouse model of Sjögren's Syndrome.
Topics: Animals; Carbachol; Cathepsins; Cells, Cultured; Disease Models, Animal; Genotype; Lacrimal Apparatu | 2016 |
Sphingosine-1-phosphate signaling in human submandibular cells.
Topics: Adult; Aged; Aged, 80 and over; Apoptosis; Boron Compounds; Calcium Signaling; Carbachol; Cell Cultu | 2010 |
Antibodies interfering with the type 3 muscarinic receptor pathway inhibit gastrointestinal motility and cholinergic neurotransmission in Sjögren's syndrome.
Topics: Acetylcholine; Analysis of Variance; Animals; Antineoplastic Combined Chemotherapy Protocols; Autoan | 2011 |
A secretagogue-small interfering RNA conjugate confers resistance to cytotoxicity in a cell model of Sjögren's syndrome.
Topics: Carbachol; Caspase Inhibitors; Cell Line; Cholinergic Agonists; Humans; RNA Interference; RNA, Small | 2011 |
Autoantibodies in Sjögren's syndrome patients acutely inhibit muscarinic receptor function.
Topics: Autoantibodies; Calcium; Calcium Signaling; Carbachol; Carrier Proteins; Cells, Cultured; Chi-Square | 2012 |
Autoantibodies in primary Sjögren's syndrome patients induce internalization of muscarinic type 3 receptors.
Topics: Adult; Aged; Autoantibodies; Calcium; Carbachol; Chloroquine; Clathrin; Down-Regulation; Female; Flu | 2012 |
Muscarinic type 3 receptor induces cytoprotective signaling in salivary gland cells through epidermal growth factor receptor transactivation.
Topics: Apoptosis; Calcium; Carbachol; Caspase 3; Caspase 7; Cell Survival; Cells, Cultured; Epidermal Growt | 2012 |
Autoantibodies against muscarinic type 3 receptor in Sjögren's syndrome inhibit aquaporin 5 trafficking.
Topics: Adult; Aged; Aquaporin 5; Autoantibodies; Calcium; Carbachol; Cell Line; Cell Membrane; Female; Huma | 2013 |
Antibodies raised against the second extracellular loop of the human muscarinic M3 receptor mimic functional autoantibodies in Sjögren's syndrome.
Topics: Amino Acid Sequence; Animals; Antibody Specificity; Autoantibodies; Carbachol; Colon; Humans; In Vit | 2004 |
Inhibitory effects of autoantibodies on the muscarinic receptors in Sjögren's syndrome.
Topics: Adult; Aquaporin 5; Aquaporins; Autoantibodies; Calcium; Calcium Channels; Carbachol; Cell Line, Tum | 2004 |
Passive transfer of Sjogren's syndrome IgG produces the pathophysiology of overactive bladder.
Topics: Animals; Autoantibodies; Carbachol; Electric Stimulation; Humans; Immunoglobulin G; In Vitro Techniq | 2004 |
Muscarinic acetylcholine type-3 receptor desensitization due to chronic exposure to Sjögren's syndrome-associated autoantibodies.
Topics: Animals; Antibodies, Blocking; Autoantibodies; Carbachol; Disease Models, Animal; Dose-Response Rela | 2006 |
Effects of autonomic agonists and immunomodulatory cytokines on polymeric immunoglobulin receptor expression by cultured rat and human salivary and colonic cell lines.
Topics: Adrenergic Agonists; Animals; Autonomic Agents; Carbachol; Cell Line; Cholinergic Agonists; Cytokine | 2007 |
Functional epitope of muscarinic type 3 receptor which interacts with autoantibodies from Sjogren's syndrome patients.
Topics: Adult; Aged; Antigen-Antibody Reactions; Autoantibodies; Calcium; Carbachol; Cells, Cultured; Epitop | 2008 |
Circulating antibodies against rat parotid gland M3 muscarinic receptors in primary Sjögren's syndrome.
Topics: Adolescent; Adrenergic beta-Agonists; Adult; Animals; Antibodies, Blocking; Atropine; Carbachol; Car | 1996 |
Stimulation with carbachol alters endomembrane distribution and plasma membrane expression of intracellular proteins in lacrimal acinar cells.
Topics: Acid Phosphatase; alpha-Glucosidases; Animals; beta-N-Acetylhexosaminidases; Carbachol; Cathepsin B; | 1999 |
Impaired microvascular response to cholinergic stimuli in primary Sjögren's syndrome.
Topics: Adult; Aged; Carbachol; Cholinergic Agonists; Female; Humans; Male; Microcirculation; Middle Aged; P | 2000 |
Inhibitory effects of muscarinic receptor autoantibodies on parasympathetic neurotransmission in Sjögren's syndrome.
Topics: Acetylcholine; Adult; Aged; Aged, 80 and over; Animals; Autoantibodies; Carbachol; Female; Humans; I | 2000 |
An investigation of interactions between the immune system and stimulus-secretion coupling in mouse submandibular acinar cells. A possible mechanism to account for reduced salivary flow rates associated with the onset of Sjögren's syndrome.
Topics: Acetylcholine; Animals; Calcium; Carbachol; Cells, Cultured; Cholinergic Agonists; Concanavalin A; C | 2000 |
G-protein signaling abnormalities mediated by CD95 in salivary epithelial cells.
Topics: Apoptosis; bcl-2-Associated X Protein; bcl-X Protein; Calcium; Carbachol; Cardiotonic Agents; Caspas | 2000 |
Lacrimal gland fluid secretion and lymphocytic infiltration in the NZB/W mouse model of Sjögren's syndrome.
Topics: Administration, Topical; Animals; Carbachol; Disease Models, Animal; Female; Lacrimal Apparatus; Lym | 2001 |
[Measurement by means of 99mTc-pertechnetate of the function of salivary glands before and after stimulation with pilocarpine in cases of sicca-syndrome of the parotidic glands (author's transl)].
Topics: Adult; Aged; Carbachol; Female; Humans; Hypopharynx; Male; Middle Aged; Parotid Gland; Pharyngeal Ne | 1979 |