Page last updated: 2024-11-07

carbachol and Scleroderma, Systemic

carbachol has been researched along with Scleroderma, Systemic in 3 studies

Carbachol: A slowly hydrolyzed CHOLINERGIC AGONIST that acts at both MUSCARINIC RECEPTORS and NICOTINIC RECEPTORS.

Scleroderma, Systemic: A chronic multi-system disorder of CONNECTIVE TISSUE. It is characterized by SCLEROSIS in the SKIN, the LUNGS, the HEART, the GASTROINTESTINAL TRACT, the KIDNEYS, and the MUSCULOSKELETAL SYSTEM. Other important features include diseased small BLOOD VESSELS and AUTOANTIBODIES. The disorder is named for its most prominent feature (hard skin), and classified into subsets by the extent of skin thickening: LIMITED SCLERODERMA and DIFFUSE SCLERODERMA.

Research Excerpts

ExcerptRelevanceReference
"Dysphagia was present only in 11 patients (44%)."2.64Esophageal dysfunction and its pathogenesis in progressive systemic sclerosis. ( Ewe, K; Korting, GW; Vogt, G; Weihrauch, TR, 1978)
"Fibrosis was quantified using the NIS Elements BR 2."1.38Gut fibrosis with altered colonic contractility in a mouse model of scleroderma. ( Denton, CP; Derrett-Smith, EC; Dooley, A; Khan, K; Shi-Wen, X; Thoua, NM, 2012)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19901 (33.33)18.7374
1990's0 (0.00)18.2507
2000's1 (33.33)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Thoua, NM1
Derrett-Smith, EC1
Khan, K1
Dooley, A1
Shi-Wen, X1
Denton, CP1
Goldblatt, F1
Gordon, TP1
Waterman, SA1
Weihrauch, TR1
Korting, GW1
Ewe, K1
Vogt, G1

Trials

1 trial available for carbachol and Scleroderma, Systemic

ArticleYear
Esophageal dysfunction and its pathogenesis in progressive systemic sclerosis.
    Klinische Wochenschrift, 1978, Oct-01, Volume: 56, Issue:19

    Topics: Adult; Aged; Carbachol; Deglutition Disorders; Esophagus; Female; Humans; Male; Manometry; Middle Ag

1978

Other Studies

2 other studies available for carbachol and Scleroderma, Systemic

ArticleYear
Gut fibrosis with altered colonic contractility in a mouse model of scleroderma.
    Rheumatology (Oxford, England), 2012, Volume: 51, Issue:11

    Topics: Animals; Carbachol; Cholinergic Agonists; Colon; Colonic Diseases; Female; Fibroblasts; Fibrosis; Ga

2012
Antibody-mediated gastrointestinal dysmotility in scleroderma.
    Gastroenterology, 2002, Volume: 123, Issue:4

    Topics: Aged; Animals; Autoantibodies; Calcium Channels, L-Type; Carbachol; Cholinergic Agonists; Colon; Fem

2002
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