Page last updated: 2024-11-07

carbachol and Prostatic Neoplasms

carbachol has been researched along with Prostatic Neoplasms in 3 studies

Carbachol: A slowly hydrolyzed CHOLINERGIC AGONIST that acts at both MUSCARINIC RECEPTORS and NICOTINIC RECEPTORS.

Prostatic Neoplasms: Tumors or cancer of the PROSTATE.

Research Excerpts

ExcerptRelevanceReference
"The LNCaP prostate cancer cells express the carbachol-sensitive M(3) -subtype of G protein-coupled receptors that cause increases in intracellular calcium and activate the family of Ca(2+) /calmodulin-dependent protein kinases (CaM Ks)."1.38CaM kinase control of AKT and LNCaP cell survival. ( Fletcher, L; Hart, B; Schmitt, JM; Smith, S, 2012)
"We conclude that, in prostate cancer epithelial cells, alpha1-ARs and m1-AChRs are functionally coupled to Ca2+-permeable DAG-gated cationic channels, for which TRPC1 and TRPC3 are the most likely candidates."1.32Receptor-coupled, DAG-gated Ca2+-permeable cationic channels in LNCaP human prostate cancer epithelial cells. ( Lepage, G; Prevarskaya, N; Roudbaraki, M; Shuba, Y; Skryma, R; Sydorenko, V; Thebault, S, 2003)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (33.33)18.2507
2000's1 (33.33)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Schmitt, JM1
Smith, S1
Hart, B1
Fletcher, L1
Sydorenko, V1
Shuba, Y1
Thebault, S1
Roudbaraki, M1
Lepage, G1
Prevarskaya, N1
Skryma, R1
Rayford, W1
Noble, MJ1
Austenfeld, MA1
Weigel, J1
Mebust, WK1
Shah, GV1

Other Studies

3 other studies available for carbachol and Prostatic Neoplasms

ArticleYear
CaM kinase control of AKT and LNCaP cell survival.
    Journal of cellular biochemistry, 2012, Volume: 113, Issue:5

    Topics: Apoptosis; bcl-Associated Death Protein; Calcium Signaling; Calcium-Calmodulin-Dependent Protein Kin

2012
Receptor-coupled, DAG-gated Ca2+-permeable cationic channels in LNCaP human prostate cancer epithelial cells.
    The Journal of physiology, 2003, May-01, Volume: 548, Issue:Pt 3

    Topics: Base Sequence; Calcium Channels; Carbachol; DNA Primers; Electrophysiology; Evoked Potentials; Human

2003
Muscarinic cholinergic receptors promote growth of human prostate cancer cells.
    The Prostate, 1997, Feb-15, Volume: 30, Issue:3

    Topics: Bromodeoxyuridine; Carbachol; DNA, Neoplasm; Humans; Immunohistochemistry; Male; Prostatic Neoplasms

1997