carbachol has been researched along with Obesity in 23 studies
Carbachol: A slowly hydrolyzed CHOLINERGIC AGONIST that acts at both MUSCARINIC RECEPTORS and NICOTINIC RECEPTORS.
Obesity: A status with BODY WEIGHT that is grossly above the recommended standards, usually due to accumulation of excess FATS in the body. The standards may vary with age, sex, genetic or cultural background. In the BODY MASS INDEX, a BMI greater than 30.0 kg/m2 is considered obese, and a BMI greater than 40.0 kg/m2 is considered morbidly obese (MORBID OBESITY).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Here, we described the effects of obesity induced by high-calorie diet and its treatment with exenatide, an anti-diabetogenic and potential anti-obesogenic drug derived from the venom of the Gila monster Heloderma suspectum, on the affinity, density, subtypes and intracellular signaling pathways linked to activation of muscarinic acetylcholine receptors (mAChRs) in rat hippocampus." | 7.91 | Effects of obesity induced by high-calorie diet and its treatment with exenatide on muscarinic acetylcholine receptors in rat hippocampus. ( Abdalla, FMF; Alponti, RF; Alves, PL; Silva, MFP; Silveira, PF, 2019) |
| "Here, we described the effects of obesity induced by high-calorie diet and its treatment with exenatide, an anti-diabetogenic and potential anti-obesogenic drug derived from the venom of the Gila monster Heloderma suspectum, on the affinity, density, subtypes and intracellular signaling pathways linked to activation of muscarinic acetylcholine receptors (mAChRs) in rat hippocampus." | 3.91 | Effects of obesity induced by high-calorie diet and its treatment with exenatide on muscarinic acetylcholine receptors in rat hippocampus. ( Abdalla, FMF; Alponti, RF; Alves, PL; Silva, MFP; Silveira, PF, 2019) |
| "To evaluate the effects of the beta-3 adrenoceptor agonist, mirabegron in a mouse model of detrusor overactivity induced by obesity." | 3.85 | Long-term treatment with the beta-3 adrenoceptor agonist, mirabegron ameliorates detrusor overactivity and restores cyclic adenosine monophosphate (cAMP) levels in obese mice. ( Alexandre, EC; Antunes, E; Calmasini, FB; Candido, TZ; da Silva, CPV; da Silva, FH; de Oliveira, MG; Mónica, FZ, 2017) |
| " Metformin treatment improved the insulin sensitivity, and normalized the in vitro bladder hypercontractility and cystometric dysfunction in obese mice." | 3.78 | Role of PKC and CaV1.2 in detrusor overactivity in a model of obesity associated with insulin resistance in mice. ( Anhê, GF; Antunes, E; Calixto, MC; De Nucci, G; Grant, AD; Leiria, LO; Lintomen, L; Mónica, FZ; Sollon, C; Zanesco, A, 2012) |
| "A single gene deletion causes lack of leptin and obesity in B6." | 3.75 | Leptin replacement restores supraspinal cholinergic antinociception in leptin-deficient obese mice. ( Baghdoyan, HA; Lydic, R; Wang, W, 2009) |
| "Determining how obesity affects function in human myometrial arteries, to help understand why childbirth has poor outcomes in obese women." | 1.51 | Human myometrial artery function and endothelial cell calcium signalling are reduced by obesity: Can this contribute to poor labour outcomes? ( Prendergast, C; Wray, S, 2019) |
| "Carbachol did not enhance glucose-induced insulin secretion in islets from 9- to 10-month-old ob/ob mice in the presence of low extracellular Na concentration." | 1.32 | Effects of cholinergic m-receptor agonists on insulin release in islets from obese and lean mice of different ages: the importance of bicarbonate. ( Lindström, P; Persson-Sjögren, S, 2004) |
| "h-1) evoked a characteristic biphasic dose-response curve for pancreatic juice and protein output in the LETO rats, whereas the OLETF rats were totally insensitive to CCK-8 stimulation." | 1.29 | Defect in pancreatic exocrine and endocrine response to CCK in genetically diabetic OLETF rats. ( Akiyama, T; Furumi, K; Kanagawa, K; Otsuki, M; Shiohara, H; Tachibana, I; Watanabe, N, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (17.39) | 18.7374 |
| 1990's | 3 (13.04) | 18.2507 |
| 2000's | 7 (30.43) | 29.6817 |
| 2010's | 9 (39.13) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Silva, MFP | 1 |
| Alves, PL | 1 |
| Alponti, RF | 1 |
| Silveira, PF | 1 |
| Abdalla, FMF | 1 |
| Yamamoto, J | 1 |
| Imai, J | 1 |
| Izumi, T | 1 |
| Takahashi, H | 1 |
| Kawana, Y | 1 |
| Takahashi, K | 1 |
| Kodama, S | 1 |
| Kaneko, K | 1 |
| Gao, J | 1 |
| Uno, K | 1 |
| Sawada, S | 1 |
| Asano, T | 1 |
| Kalinichenko, VV | 1 |
| Susaki, EA | 1 |
| Kanzaki, M | 1 |
| Ueda, HR | 1 |
| Ishigaki, Y | 1 |
| Yamada, T | 1 |
| Katagiri, H | 1 |
| Orfanos, S | 1 |
| Jude, J | 1 |
| Deeney, BT | 1 |
| Cao, G | 1 |
| Rastogi, D | 1 |
| van Zee, M | 1 |
| Pushkarsky, I | 1 |
| Munoz, HE | 1 |
| Damoiseaux, R | 1 |
| Di Carlo, D | 1 |
| Panettieri, RA | 1 |
| Prendergast, C | 1 |
| Wray, S | 1 |
| Lubaczeuski, C | 2 |
| Balbo, SL | 3 |
| Ribeiro, RA | 2 |
| Vettorazzi, JF | 1 |
| Santos-Silva, JC | 1 |
| Carneiro, EM | 3 |
| Bonfleur, ML | 3 |
| Mendes, MC | 1 |
| Maller, AC | 1 |
| Calmasini, FB | 1 |
| de Oliveira, MG | 1 |
| Alexandre, EC | 1 |
| da Silva, FH | 1 |
| da Silva, CPV | 1 |
| Candido, TZ | 1 |
| Antunes, E | 2 |
| Mónica, FZ | 2 |
| Wang, W | 1 |
| Baghdoyan, HA | 1 |
| Lydic, R | 1 |
| Andreazzi, AE | 1 |
| Grassiolli, S | 1 |
| Marangon, PB | 1 |
| Martins, AG | 1 |
| de Oliveira, JC | 1 |
| Torrezan, R | 1 |
| Gravena, C | 1 |
| Garcia, RM | 1 |
| Mathias, PC | 2 |
| Leiria, LO | 1 |
| Sollon, C | 1 |
| Calixto, MC | 1 |
| Lintomen, L | 1 |
| Anhê, GF | 1 |
| De Nucci, G | 1 |
| Zanesco, A | 1 |
| Grant, AD | 1 |
| Amaral, ME | 1 |
| Filiputti, E | 1 |
| Persson-Sjögren, S | 1 |
| Lindström, P | 1 |
| Yoshimura, R | 2 |
| Omori, H | 2 |
| Somekawa, S | 2 |
| Osaka, T | 1 |
| Ito, R | 1 |
| Inoue, S | 1 |
| Endo, Y | 2 |
| Zawalich, WS | 2 |
| Kelley, GG | 1 |
| Tachibana, I | 1 |
| Akiyama, T | 1 |
| Kanagawa, K | 2 |
| Shiohara, H | 1 |
| Furumi, K | 1 |
| Watanabe, N | 1 |
| Otsuki, M | 2 |
| Nakamura, H | 1 |
| Kihara, Y | 1 |
| Tashiro, M | 1 |
| Shirohara, H | 1 |
| Yamamoto, M | 1 |
| Yoshikawa, H | 1 |
| Fukumitsu, K | 1 |
| Hirohata, Y | 1 |
| Zawalich, KC | 1 |
| Naderali, EK | 1 |
| Williams, G | 1 |
| Trimble, ER | 1 |
| Bruzzone, R | 1 |
| Lundquist, I | 1 |
| Saunders, WS | 1 |
| Thornhill, JA | 1 |
| Wayner, MJ | 1 |
| Carey, RJ | 1 |
2 reviews available for carbachol and Obesity
| Article | Year |
|---|---|
The pathogenesis of NIDDM: the role of the pancreatic beta cell.
Topics: Animals; Carbachol; Cholinergic Agents; Diabetes Mellitus; Diabetes Mellitus, Type 2; Glucose; Human | 1995 |
Basic drives.
Topics: Animals; Appetite Regulation; Atropine; Behavior, Animal; Body Temperature Regulation; Body Weight; | 1973 |
21 other studies available for carbachol and Obesity
| Article | Year |
|---|---|
Effects of obesity induced by high-calorie diet and its treatment with exenatide on muscarinic acetylcholine receptors in rat hippocampus.
Topics: Animals; Carbachol; Energy Intake; Exenatide; Glucagon-Like Peptide-1 Receptor; Hippocampus; Male; O | 2019 |
Neuronal signals regulate obesity induced β-cell proliferation by FoxM1 dependent mechanism.
Topics: Animals; Blood Glucose; Brain; Carbachol; Cell Proliferation; Cholinergic Agonists; Forkhead Box Pro | 2017 |
Obesity increases airway smooth muscle responses to contractile agonists.
Topics: Adult; Asthma; Calcium; Carbachol; Cardiotonic Agents; Case-Control Studies; Cells, Cultured; Female | 2018 |
Human myometrial artery function and endothelial cell calcium signalling are reduced by obesity: Can this contribute to poor labour outcomes?
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adult; Arginine Vasopressin; Art | 2019 |
Vagotomy ameliorates islet morphofunction and body metabolic homeostasis in MSG-obese rats.
Topics: Animals; Carbachol; Cell Count; Cholesterol; Cholinergic Agonists; Flavoring Agents; Glucose; Homeos | 2015 |
Vagotomy diminishes obesity in cafeteria rats by decreasing cholinergic potentiation of insulin release.
Topics: 1-Methyl-3-isobutylxanthine; Adipose Tissue; Animals; Body Weight; Carbachol; Colforsin; Cyclic AMP; | 2016 |
Long-term treatment with the beta-3 adrenoceptor agonist, mirabegron ameliorates detrusor overactivity and restores cyclic adenosine monophosphate (cAMP) levels in obese mice.
Topics: Acetanilides; Adrenergic beta-3 Receptor Agonists; Animals; Body Weight; Carbachol; Cyclic AMP; Cycl | 2017 |
Leptin replacement restores supraspinal cholinergic antinociception in leptin-deficient obese mice.
Topics: Acetylcholine; Adenosine; Animals; Carbachol; Cholinergic Agonists; Cholinesterase Inhibitors; Hot T | 2009 |
Impaired sympathoadrenal axis function contributes to enhanced insulin secretion in prediabetic obese rats.
Topics: Adrenal Medulla; Animals; Blood Glucose; Caffeine; Carbachol; Catecholamines; Glucose Tolerance Test | 2011 |
Role of PKC and CaV1.2 in detrusor overactivity in a model of obesity associated with insulin resistance in mice.
Topics: Adiposity; Amlodipine; Animals; Body Weight; Calcium Channel Blockers; Calcium Channels, L-Type; Cal | 2012 |
Parasympathetic activity changes insulin response to glucose and neurotransmitters.
Topics: Analysis of Variance; Animals; Carbachol; Glucose; In Vitro Techniques; Islets of Langerhans; Kineti | 2002 |
Effects of cholinergic m-receptor agonists on insulin release in islets from obese and lean mice of different ages: the importance of bicarbonate.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Acetylcholine; Age Factors; Amiloride; Ammonium Ch | 2004 |
Continuous carbachol infusion promotes peripheral cell proliferation and mimics vagus hyperactivity in a rat model of hypothalamic obesity.
Topics: Animals; Body Weight; Carbachol; Cell Proliferation; Cholinergic Agonists; Disease Models, Animal; D | 2006 |
Carbachol induces hepatocyte proliferation, but only in the presence of hepatic nonparenchymal cells.
Topics: Animals; Carbachol; Cell Proliferation; Cells, Cultured; Cholinergic Agonists; Coculture Techniques; | 2007 |
Defect in pancreatic exocrine and endocrine response to CCK in genetically diabetic OLETF rats.
Topics: Acute Disease; Animals; Carbachol; Caseins; Ceruletide; Cholecystokinin; Duodenum; Gastric Acid; Glu | 1996 |
Defects of cholecystokinin (CCK)-A receptor gene expression and CCK-A receptor-mediated biological functions in Otsuka Long-Evans Tokushima Fatty (OLETF) rats.
Topics: Animals; Arginine; Blood Glucose; Blotting, Northern; Blotting, Southern; Brain; Carbachol; DNA Prim | 1998 |
A link between insulin resistance and hyperinsulinemia: inhibitors of phosphatidylinositol 3-kinase augment glucose-induced insulin secretion from islets of lean, but not obese, rats.
Topics: Androstadienes; Animals; Calcium; Carbachol; Cell Separation; Enzyme Inhibitors; Glucose; Hyperinsul | 2000 |
Effects of short-term feeding of a highly palatable diet on vascular reactivity in rats.
Topics: Aldehydes; Animal Feed; Animals; Arteriosclerosis; Carbachol; Cholinergic Agonists; Dietary Fats; En | 2001 |
Abnormalities of caerulein- and carbamylcholine-stimulated pancreatic enzyme secretion in the obese Zucker rat.
Topics: Amylases; Animals; Blood Glucose; Body Weight; Carbachol; Ceruletide; Female; Homozygote; In Vitro T | 1985 |
Lysosomal enzyme activities in pancreatic islets from normal and obese hyperglycemic mice.
Topics: Acetylglucosaminidase; Acid Phosphatase; Animals; Blood Glucose; Carbachol; Cathepsin D; Fasting; Fe | 1985 |
No inotropic action of enkephalins or enkephalin derivatives on electrically-stimulated atria isolated from lean and obese rats.
Topics: Animals; Atrial Function; Carbachol; Electric Stimulation; Enkephalin, Leucine; Enkephalin, Leucine- | 1985 |