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carbachol and Narcolepsy

carbachol has been researched along with Narcolepsy in 4 studies

Carbachol: A slowly hydrolyzed CHOLINERGIC AGONIST that acts at both MUSCARINIC RECEPTORS and NICOTINIC RECEPTORS.

Narcolepsy: A condition characterized by recurrent episodes of daytime somnolence and lapses in consciousness (microsomnias) that may be associated with automatic behaviors and AMNESIA. CATAPLEXY; SLEEP PARALYSIS, and hypnagogic HALLUCINATIONS frequently accompany narcolepsy. The pathophysiology of this disorder includes sleep-onset rapid eye movement (REM) sleep, which normally follows stage III or IV sleep. (From Neurology 1998 Feb;50(2 Suppl 1):S2-S7)

Research Excerpts

ExcerptRelevanceReference
"Narcolepsy is a chronic sleep disorder marked by excessive daytime sleepiness, cataplexy, sleep paralysis, and hypnagogic hallucinations."1.31Is narcolepsy a REM sleep disorder? Analysis of sleep abnormalities in narcoleptic Dobermans. ( Hong, J; Kwan, M; Mignot, E; Nishino, S; Reid, M; Riehl, J, 2000)
"Narcolepsy is a sleep disorder characterized by excessive daytime sleepiness and rapid eye movement (REM) sleep-related symptoms, such as cataplexy."1.29Muscle atonia is triggered by cholinergic stimulation of the basal forebrain: implication for the pathophysiology of canine narcolepsy. ( Dement, WC; Mignot, E; Nishino, S; Reid, MS; Shelton, J; Siegel, JM; Tafti, M, 1995)
"Carbachol and atropine were perfused through microdialysis probes implanted bilaterally in the pontine reticular formation of freely moving, narcoleptic and control Doberman pinschers."1.29Cholinergic mechanisms in canine narcolepsy--I. Modulation of cataplexy via local drug administration into the pontine reticular formation. ( Dement, WC; Geary, JN; Mignot, E; Nishino, S; Reid, MS; Siegel, JM; Tafti, M, 1994)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (75.00)18.2507
2000's1 (25.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Nishino, S4
Tafti, M2
Reid, MS3
Shelton, J1
Siegel, JM2
Dement, WC3
Mignot, E4
Geary, JN1
Riehl, J1
Hong, J1
Kwan, M1
Reid, M1

Reviews

1 review available for carbachol and Narcolepsy

ArticleYear
Neuropharmacology and neurochemistry of canine narcolepsy.
    Sleep, 1994, Volume: 17, Issue:8 Suppl

    Topics: Acetylcholine; Animals; Brain; Carbachol; Catalepsy; Dogs; Narcolepsy; Neurotransmitter Agents; Rece

1994

Other Studies

3 other studies available for carbachol and Narcolepsy

ArticleYear
Muscle atonia is triggered by cholinergic stimulation of the basal forebrain: implication for the pathophysiology of canine narcolepsy.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1995, Volume: 15, Issue:7 Pt 1

    Topics: Animals; Carbachol; Cataplexy; Cholinergic Agents; Dogs; Electroencephalography; Female; Male; Muscl

1995
Cholinergic mechanisms in canine narcolepsy--I. Modulation of cataplexy via local drug administration into the pontine reticular formation.
    Neuroscience, 1994, Volume: 59, Issue:3

    Topics: Analysis of Variance; Animals; Atropine; Carbachol; Cataplexy; Dog Diseases; Dogs; Electroencephalog

1994
Is narcolepsy a REM sleep disorder? Analysis of sleep abnormalities in narcoleptic Dobermans.
    Neuroscience research, 2000, Volume: 38, Issue:4

    Topics: Animals; Basal Nucleus of Meynert; Brain; Carbachol; Cataplexy; Cholinergic Agonists; Circadian Rhyt

2000