carbachol has been researched along with Myasthenia Gravis in 24 studies
Carbachol: A slowly hydrolyzed CHOLINERGIC AGONIST that acts at both MUSCARINIC RECEPTORS and NICOTINIC RECEPTORS.
Myasthenia Gravis: A disorder of neuromuscular transmission characterized by fatigable weakness of cranial and skeletal muscles with elevated titers of ACETYLCHOLINE RECEPTORS or muscle-specific receptor tyrosine kinase (MuSK) autoantibodies. Clinical manifestations may include ocular muscle weakness (fluctuating, asymmetric, external ophthalmoplegia; diplopia; ptosis; and weakness of eye closure) and extraocular fatigable weakness of facial, bulbar, respiratory, and proximal limb muscles. The disease may remain limited to the ocular muscles (ocular myasthenia). THYMOMA is commonly associated with this condition.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The apparent KD for CARB, estimated from the dose-response curve for 22Na influx, was unaffected." | 1.27 | The effects of a myasthenic serum on the acetylcholine receptors of C2 myotubes. II. Functional inactivation of the receptor. ( Gu, Y; Hall, Z; Hestrin, S; Maricq, AV, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 17 (70.83) | 18.7374 |
| 1990's | 6 (25.00) | 18.2507 |
| 2000's | 1 (4.17) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| ELMQVIST, D | 1 |
| HOFMANN, WW | 1 |
| KUGELBERG, J | 1 |
| QUASTEL, DM | 1 |
| Psaridi-Linardaki, L | 1 |
| Mamalaki, A | 1 |
| Tzartos, SJ | 1 |
| Kim, YI | 1 |
| Sanders, DB | 1 |
| Ashizawa, T | 2 |
| Elias, SB | 2 |
| Appel, SH | 3 |
| Blosser, JC | 1 |
| McManaman, JL | 1 |
| Mizuno, Y | 2 |
| Humphrey, J | 1 |
| Dosch, HM | 2 |
| Gelfand, EW | 2 |
| Kubota, M | 1 |
| Yoshida, T | 1 |
| Shinomiya, K | 1 |
| Mikawa, H | 1 |
| Mihovilovic, M | 1 |
| Donnelly-Roberts, D | 1 |
| Richman, DP | 2 |
| Martinez-Carrion, M | 1 |
| Stuhlmüller, B | 1 |
| Kalden, JR | 1 |
| Fahlbusch, R | 1 |
| Hain, N | 1 |
| Manger, B | 1 |
| Vincent, A | 4 |
| Li, Z | 1 |
| Hart, A | 1 |
| Barrett-Jolley, R | 1 |
| Yamamoto, T | 1 |
| Burges, J | 1 |
| Wray, D | 1 |
| Byrne, N | 1 |
| Molenaar, P | 1 |
| Newsom-Davis, J | 4 |
| Plested, CP | 1 |
| Trotter, JL | 1 |
| Ringel, SP | 1 |
| Cook, JD | 1 |
| Engel, WK | 1 |
| Eldefrawi, ME | 1 |
| McFarlin, DE | 1 |
| Arnason, BG | 1 |
| Almon, RR | 1 |
| Lindstrom, J | 2 |
| Einarson, B | 1 |
| Francy, M | 1 |
| Sipka, S | 1 |
| Diószeghy, P | 1 |
| Mechler, F | 1 |
| Lukács, K | 1 |
| Szelényi, J | 1 |
| Szegedi, G | 1 |
| Conroy, WG | 1 |
| Saedi, MS | 1 |
| Maricq, AV | 1 |
| Gu, Y | 1 |
| Hestrin, S | 1 |
| Hall, Z | 1 |
| Lang, B | 1 |
| Richardson, G | 1 |
| Rees, J | 1 |
| Martin, K | 1 |
| Thesleff, S | 1 |
| Nastuk, WL | 1 |
1 review available for carbachol and Myasthenia Gravis
| Article | Year |
|---|---|
Serum acetylcholine-receptor antibodies in myasthenia gravis.
Topics: Animals; Antibodies; Antigens; Binding Sites; Bungarotoxins; Carbachol; Decamethonium Compounds; Dep | 1976 |
23 other studies available for carbachol and Myasthenia Gravis
| Article | Year |
|---|---|
AN ELECTROPHYSIOLOGICAL INVESTIGATION OF NEUROMUSCULAR TRANSMISSION IN MYASTHENIA GRAVIS.
Topics: Acetylcholine; Calcium; Carbachol; Decamethonium Compounds; Electromyography; Electrophysiology; Mag | 1964 |
Future therapeutic strategies in autoimmune myasthenia gravis.
Topics: Animals; Antibodies, Anti-Idiotypic; Antibodies, Monoclonal; Antibody Specificity; Autoantibodies; B | 2003 |
Further electrophysiological studies of neuromuscular transmission in an animal model of myasthenia gravis.
Topics: Action Potentials; Animals; Carbachol; Disease Models, Animal; Evoked Potentials; Female; Myasthenia | 1981 |
Interaction of myasthenic immunoglobulins and cholinergic agonists on acetylcholine receptors of rat myotubes.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Bungarotoxins; Carbachol; Culture Techniques; Dose | 1982 |
The effects of carbamylcholine, calcium, and cyclic nucleotides on acetylcholine receptor synthesis in cultured myotubes.
Topics: Animals; Antibodies; Calcium; Carbachol; Cells, Cultured; Cholera Toxin; Immunoglobulin G; Muscles; | 1981 |
Carbamylcholine modulation of E-rosette formation. Effect of plasmapheresis in myasthenia gravis.
Topics: Adolescent; Adult; Aged; Atropine; Carbachol; Child; Female; Humans; Immunoglobulin G; Leukocyte Cou | 1982 |
Carbamycholine modulation of E-rosette formation: identification of nicotinic acetylcholine receptors on a subpopulation of human T lymphocytes.
Topics: Animals; Carbachol; Erythrocytes; Humans; In Vitro Techniques; Lithium; Myasthenia Gravis; Organ Spe | 1982 |
Serum factor in myasthenia gravis inhibits induction of "active" E by carbachol.
Topics: Animals; Carbachol; Chromatography, Gel; Dialysis; Dose-Response Relationship, Immunologic; Erythroc | 1980 |
Pathogenesis of hyperacute experimental autoimmune myasthenia gravis. Acetylcholine receptor/cholinergic site/receptor function/autoimmunity.
Topics: Animals; Antibodies, Monoclonal; Autoimmunity; Bungarotoxins; Carbachol; Cholinergic Antagonists; Di | 1994 |
Immunological and functional properties of the acetylcholine receptor expressed on the human cell line TE671.
Topics: Autoantibodies; Bungarotoxins; Calcium; Carbachol; Carrier Proteins; Cells, Cultured; Chromatography | 1993 |
Seronegative myasthenia gravis. Evidence for plasma factor(s) interfering with acetylcholine receptor function.
Topics: Acetylcholine; Autoantibodies; Carbachol; Cells, Cultured; Female; Humans; In Vitro Techniques; Ion | 1993 |
Seronegative myasthenia plasmas and non-IgG fractions transiently inhibit nAChR function.
Topics: Calcitonin Gene-Related Peptide; Carbachol; Cell Line; Cyclic AMP-Dependent Protein Kinases; Enzyme | 1998 |
Morphologic and immunologic studies in experimental autoimmune myasthenia gravis and myasthenia gravis.
Topics: Acetylcholine; Animals; Antibody Formation; Autoimmune Diseases; Binding Sites, Antibody; Bungarotox | 1977 |
Nicotinic acetylcholine receptor: evidence for a functionally distinct receptor on human lymphocytes.
Topics: Carbachol; Cell Division; Dose-Response Relationship, Drug; Humans; Lymphocyte Activation; Lymphocyt | 1979 |
alpha-Bungarotoxin and anti-acetylcholine receptor antibody binding to the human acetylcholine receptor.
Topics: Acetylcholine; Animals; Antibodies; Binding Sites, Antibody; Binding, Competitive; Bungarotoxins; Ca | 1979 |
Acetylcholine receptors and myasthenia gravis: the effect of antibodies to eel acetylcholine receptors on eel electric organ cells.
Topics: Animals; Antibodies; Carbachol; Dose-Response Relationship, Immunologic; Electric Organ; Electrophor | 1977 |
Decrease in the carbamylcholine-induced chemotaxis of monocytes in myasthenia gravis.
Topics: Carbachol; Chemotaxis, Leukocyte; Follow-Up Studies; Humans; Immune Tolerance; Monocytes; Myasthenia | 1991 |
TE671 cells express an abundance of a partially mature acetylcholine receptor alpha subunit which has characteristics of an assembly intermediate.
Topics: Animals; Antibodies, Monoclonal; Antigens, Surface; Autoantibodies; Binding, Competitive; Bungarotox | 1990 |
The effects of a myasthenic serum on the acetylcholine receptors of C2 myotubes. II. Functional inactivation of the receptor.
Topics: Animals; Antibodies; Blood; Bungarotoxins; Carbachol; Cell Line; Electrophysiology; Ion Channels; Mu | 1985 |
Plasma from myasthenia gravis patients reduces acetylcholine receptor agonist-induced Na+ flux into TE671 cell line.
Topics: Adult; Autoantibodies; Biological Transport; Bungarotoxins; Carbachol; Female; Humans; Ion Channels; | 1988 |
Effects of quaternary ammonium compounds on choline transport in red cells.
Topics: Acetylcholine; Biological Transport, Active; Carbachol; Choline; Decamethonium Compounds; Erythrocyt | 1969 |
Acetylcholine utulization in myasthenia gravis.
Topics: Acetylcholine; Carbachol; Decamethonium Compounds; Humans; In Vitro Techniques; Muscles; Myasthenia | 1966 |
Mechanisms of neuromuscular blockade.
Topics: Acetylcholine; Animals; Anura; Binding Sites; Calcium; Carbachol; In Vitro Techniques; Magnesium; Me | 1971 |