carbachol has been researched along with Muscle Contraction in 2032 studies
Carbachol: A slowly hydrolyzed CHOLINERGIC AGONIST that acts at both MUSCARINIC RECEPTORS and NICOTINIC RECEPTORS.
Muscle Contraction: A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Mirabegron is used for treatment of storage symptoms in overactive bladder (OAB) caused by spontaneous bladder smooth muscle contractions." | 8.12 | Inhibition of Full Smooth Muscle Contraction in Isolated Human Detrusor Tissues by Mirabegron Is Limited to Off-Target Inhibition of Neurogenic Contractions. ( Hennenberg, M; Huang, R; Stief, CG; Strittmatter, F; Tamalunas, A; Waidelich, R, 2022) |
| "What is the central question of this study? Acute acidosis that results from short-term exercise is involved in delayed gastric emptying in rats and the lower responsiveness of gastric fundus strips to carbachol." | 7.85 | Extracellular acidosis selectively inhibits pharmacomechanical coupling induced by carbachol in strips of rat gastric fundus. ( Batista-Lima, FJ; da Silva, MTB; de Carvalho, EF; de Oliveira, DMN; Dos Santos, AA; Havt, A; Magalhães, PJC, 2017) |
| "The aim of this study was to compare the effect of antimuscarinic antagonists on carbachol-induced contraction of normal human bladder and detrusor overactivity associated with benign prostatic hyperplasia (DO/BPH)." | 7.81 | The role of muscarinic receptor subtypes on carbachol-induced contraction of normal human detrusor and overactive detrusor associated with benign prostatic hyperplasia. ( Fuse, M; Kaga, K; Kamai, T; Shibata, C; Uchiyama, T; Yamanishi, T, 2015) |
| "To investigate a possible relation between hypercholesterolemia and detrusor smooth muscle function, we studied the contractile response to potassium challenge, carbachol (CCh), and the components of CCh-induced contractile mechanism in high-cholesterol diet-fed rats." | 7.78 | The effect of hypercholesterolemia on carbachol-induced contractions of the detrusor smooth muscle in rats: increased role of L-type Ca2+ channels. ( Balkanci, ZD; Bayrak, S; Erdem, A; Karabulut, I; Karaismailoğlu, S; Pehlivanoğlu, B, 2012) |
| " In this study we examine the expression and function of FIZZ1 in an ovalbumin mouse model of asthma." | 7.76 | FIZZ1 potentiates the carbachol-induced tracheal smooth muscle contraction. ( Bowman, MR; Chen, H; Jacobson, BA; Mason, L; Wolf, SF, 2010) |
| "To investigate the effect of curcumin on colitis-induced reduction of carbachol-induced contraction in colon segments from rats treated with trinitrobenzenesulphonic acid." | 7.75 | Curcumin reverses attenuated carbachol-induced contraction of the colon in a rat model of colitis. ( Khan, I; Lubbad, AS; Oriowo, MA, 2009) |
| "Ascorbic acid and citric acid augmented bladder muscle contraction possibly by enhanced Ca(2+) influx." | 7.75 | Modification of rat detrusor muscle contraction by ascorbic acid and citric acid involving enhanced neurotransmitter release and Ca2+ influx. ( Dasgupta, J; Elliott, RA; Tincello, DG, 2009) |
| " Since amikacin was reported to affect neurotransmission by a prejunctional mechanism, we investigated the effect of amikacin on isolated detrusor smooth muscle contraction to further evaluate its potential relaxant properties." | 7.74 | In vitro effect of amikacin on rat and human detrusor muscle contraction. ( Bassi, P; Gardi, M; Nigro, F; Pinto, F; Ragazzi, E; Sacco, E; Totaro, A; Volpe, A, 2008) |
| "To determine the efficacy of coenzyme Q10 (CoQ10) and alpha-lipoic acid (alpha-LA), either alone or in combination, to protect the contractile responses of the rabbit urinary bladder from damage caused by repetitive stimulation in the presence or absence of in vitro ischemia." | 7.74 | Effect of co-enzyme Q10 and alpha-lipoic acid on response of rabbit urinary bladder to repetitive stimulation and in vitro ischemia. ( Levin, RM; Lin, WY; Rehfuss, A; Schuler, C, 2008) |
| "To investigate the effects of menthol, an activator of the temperature-sensitive transient receptor potential family member TRPM8, on detrusor smooth-muscle contraction and the micturition reflex in rats." | 7.74 | Effect of menthol on detrusor smooth-muscle contraction and the micturition reflex in rats. ( Harada, K; Ikeda, S; Kamikawa, Y; Kawahira, K; Nomoto, Y; Ohwatashi, A; Yoshida, A, 2008) |
| "1 - 100 microM) inhibited carbachol- and high K +-induced muscle contractions in a concentration-dependent fashion, but did not affect basal muscle tension." | 7.72 | Inhibition of smooth muscle contraction by magnolol and honokiol in porcine trachea. ( Chan, MH; Chen, HH; Ko, CH; Lin, YR, 2003) |
| " This study investigates the effect of erythromycin on rat detrusor muscle contractile response to characterise its potential as an alternative inhibitor of bladder muscle contraction." | 7.72 | Direct inhibition of rat detrusor muscle contraction by erythromycin. ( Elliott, RA; England, RC; Norman, RI, 2004) |
| "The aim of this study was to determine the effects of nimesulide and pentoxifylline on the contractile effects of KCl, carbachol and substance P in the longitudinal muscle of rat ileum during peritonitis." | 7.71 | Effects of nimesulide and pentoxifylline on decreased contractile responses in rat ileum with peritonitis. ( Arpacik, M; Karadas, B; Kaya, TT; Koyluoglu, G; Soydan, AS, 2002) |
| "We examined the bladder function of cystitis models induced by intravesical acetone instillation in urethane-anesthetized rats." | 7.70 | Urodynamics in acetone-induced cystitis of anesthetized rats. ( Hosoki, K; Kawashima, K; Shimizu, I, 1999) |
| "The effect of the calcium antagonists omega-conotoxin GVIA, verapamil, gallopamil and diltiazem was investigated on in vitro bronchial smooth muscle contraction in the rat induced by the nerve agent soman." | 7.68 | Effect of calcium antagonists (omega-conotoxin GVIA, verapamil, gallopamil, diltiazem) on bronchial smooth muscle contractions induced by soman. ( Aas, P; Fyllingen, E; Walday, P, 1992) |
| " The effects of haloperidol on smooth muscle contraction induced by carbachol, histamine, high K or caffeine in the presence or absence of extracellular Ca were investigated." | 7.68 | Haloperidol differentiates smooth muscle contractions induced by release of intracellularly stored Ca and by influx of extracellular Ca. ( Hishinuma, S; Hongo, I; Kurokawa, M; Uchida, MK, 1992) |
| "The present study examined 15 patients previously resistant to conventional antihistamines, in which doxepin at doses in the range of 50-75 mg/day was shown to be effective in treatment of chronic urticaria and without significant adverse side effects." | 7.68 | Mechanism of action of doxepin in the treatment of chronic urticaria. ( Almeida, L; Figueiredo, A; Gonçalo, M; Poiares-Baptista, A; Ribeiro, CA; Teixeira, F, 1990) |
| "A series of tertiary 3- and 4-haloalkylamines related to the muscarinic agent oxotremorine was synthesized." | 7.67 | Tertiary 3- and 4-haloalkylamine analogues of oxotremorine as prodrugs of potent muscarinic agonists. ( Jenden, DJ; Ringdahl, B; Roch, M, 1988) |
| "The enantiomers of three 5-methyl-2-pyrrolidone analogues of the muscarinic agent oxotremorine (1) were synthesized." | 7.67 | Stereoselectivity of muscarinic receptors in vivo and in vitro for oxotremorine analogues. N-[4-(tertiary amino)-2-butynyl]-5-methyl-2-pyrrolidones. ( Amstutz, R; Jenden, DJ; Karlén, B; Ringdahl, B; Roch, M, 1985) |
| "Cyclic nucleotide levels and tension were measured at various times during carbachol-induced smooth muscle contractions." | 7.65 | Cyclic nucleotide levels during carbachol-induced smooth muscle contractions. ( Hartle, DK, 1976) |
| "Pretreatment with curcumin caused a remarkable decrease in histopathological parameters such as edema, congestion and inflammatory cells." | 5.38 | Role of curcumin in mesenteric ischemia - reperfusion injury in rats. ( Belviranli, M; Esen, H; Gokbel, H; Nurullahoglu-Atalik, KE; Okudan, N; Oz, M, 2012) |
| "Lidocaine can cause direct ASM relaxation by decreasing [Ca(2+)]i." | 5.35 | Effect of lidocaine on endothelin-1-mediated airway smooth muscle contraction in the rat trachea. ( Akhtar, S; Brull, SJ; Harrison, BA; Podgoreanu, M, 2008) |
| "To investigate the effects of anoxia and glucopenia (A-G) on both male and female guinea pig urinary bladder." | 5.34 | Gender-related neuronal and smooth muscle damage of guinea pig isolated urinary bladder from anoxia-glucopenia and reperfusion injury and its relationship to glycogen content. ( Dragoni, S; Pessina, F; Sgaragli, G; Valeri, A; Valoti, M, 2007) |
| "Pretreatment with atorvastatin caused remarkable decrease in both oxidative stress and neutrophil accumulation." | 5.34 | Attenuation of contractile dysfunction by atorvastatin after intestinal ischemia reperfusion injury in rats. ( Cetin, A; Igdem, AA; Ozacmak, ID; Ozacmak, VH; Sayan, H, 2007) |
| "Melatonin treatment of the CLP group restored these responses." | 5.32 | Melatonin treatment protects against sepsis-induced functional and biochemical changes in rat ileum and urinary bladder. ( Ayanoğlu-Dülger, G; Kapucu, C; Paskaloğlu, K; Sener, G, 2004) |
| "Colitis was induced by intracolonic instillation of 4% acetic acid." | 5.32 | Electroacupuncture ameliorates experimental colitis induced by acetic acid in rat. ( Kang, JW; Kim, HJ; Kim, JY; Kim, TW; Kwon, YB; La, JH; Sung, TS; Yang, IS, 2004) |
| "We performed a comparative study of the effects of carbachol, α,β-methylene-ATP, β,γ-methylene-ATP, and electric field stimulation on the contractile activity of the isolated uterus from rats aged 3 and 9 months with valproic model of autism." | 4.31 | Comparative Assessment of Disturbances of Contractions of the Isolated Uterus in 3- and 9-Month-Old Rats with a Model of Autism. ( Ivanova, DV; Ziganshin, AU, 2023) |
| "Mirabegron is used for treatment of storage symptoms in overactive bladder (OAB) caused by spontaneous bladder smooth muscle contractions." | 4.12 | Inhibition of Full Smooth Muscle Contraction in Isolated Human Detrusor Tissues by Mirabegron Is Limited to Off-Target Inhibition of Neurogenic Contractions. ( Hennenberg, M; Huang, R; Stief, CG; Strittmatter, F; Tamalunas, A; Waidelich, R, 2022) |
| "Subarachnoid hemorrhage stimulates apoptosis of the rabbit bladder and impairs the contractile response of the rabbit bladder to carbachol." | 3.96 | Hyperbaric oxygen therapy prevents subarachnoid hemorrhage-induced apoptosis and impaired contractility of the rabbit bladder. ( Cadirci, S; Celik, O; Cevik, O; Oroglu, B; Sekerci, CA; Sener, G; Tarcan, T; Tinay, I, 2020) |
| "What is the central question of this study? Acute acidosis that results from short-term exercise is involved in delayed gastric emptying in rats and the lower responsiveness of gastric fundus strips to carbachol." | 3.85 | Extracellular acidosis selectively inhibits pharmacomechanical coupling induced by carbachol in strips of rat gastric fundus. ( Batista-Lima, FJ; da Silva, MTB; de Carvalho, EF; de Oliveira, DMN; Dos Santos, AA; Havt, A; Magalhães, PJC, 2017) |
| "To evaluate the effects of the beta-3 adrenoceptor agonist, mirabegron in a mouse model of detrusor overactivity induced by obesity." | 3.85 | Long-term treatment with the beta-3 adrenoceptor agonist, mirabegron ameliorates detrusor overactivity and restores cyclic adenosine monophosphate (cAMP) levels in obese mice. ( Alexandre, EC; Antunes, E; Calmasini, FB; Candido, TZ; da Silva, CPV; da Silva, FH; de Oliveira, MG; Mónica, FZ, 2017) |
| " The aim of this study was to investigate the effects of desflurane at different concentrations and durations in an ovalbumin-sensitized guinea pig model of airway hyper-responsiveness." | 3.85 | Time- and Dose-Dependent Effects of Desflurane in Sensitized Airways. ( Iwasaki, S; Yamakage, M; Zhou, J, 2017) |
| " The efficacy of the P20 peptide in vivo on airway hyperresponsiveness (AHR) was determined in an ovalbumin (OVA) sensitization and challenge murine model of allergic airway inflammation." | 3.83 | Heat Shock-Related Protein 20 Peptide Decreases Human Airway Constriction Downstream of β2-Adrenergic Receptor. ( Banathy, A; Boyd, KL; Cheung-Flynn, J; Goleniewska, K; Komalavilas, P; Newcomb, DC; Peebles, RS, 2016) |
| " In order to elucidate the role of Ser/Thr protein phosphatase 2A (PP2A) in ciliary muscle contraction, we examined the effects of okadaic acid and other PP2A inhibitors on contractions induced by carbachol (CCh) and ionomycin in bovine ciliary muscle strips (BCM)." | 3.81 | Force-inhibiting effect of Ser/Thr protein phosphatase 2A inhibitors on bovine ciliary muscle. ( Ishida, M; Miyazu, M; Takai, A; Takeya, K; Yoshida, A, 2015) |
| "The results showed that the airway smooth muscle contraction induced by the depolarizing agent (KCl) and cholinergic agonist (carbachol) was markedly reduced by R." | 3.81 | Relaxant effects of a hydroalcoholic extract of Ruta graveolens on isolated rat tracheal rings. ( Águila, L; de Campos, RR; Mansilla, K; Ordenes, J; Romero, F; Ruedlinger, J; Salvatici, R, 2015) |
| "The aim of this study was to compare the effect of antimuscarinic antagonists on carbachol-induced contraction of normal human bladder and detrusor overactivity associated with benign prostatic hyperplasia (DO/BPH)." | 3.81 | The role of muscarinic receptor subtypes on carbachol-induced contraction of normal human detrusor and overactive detrusor associated with benign prostatic hyperplasia. ( Fuse, M; Kaga, K; Kamai, T; Shibata, C; Uchiyama, T; Yamanishi, T, 2015) |
| "Telokin phosphorylation by cyclic GMP-dependent protein kinase facilitates smooth muscle relaxation." | 3.81 | Role of Telokin in Regulating Murine Gastric Fundus Smooth Muscle Tension. ( An, C; Bhetwal, BP; Perrino, BA; Sanders, KM; Somlyo, AV, 2015) |
| " Hypothesizing that proton pump inhibitors also reduce gastroesophageal muscle contraction in newborn and juvenile rats, we evaluated the in vitro effect of pantoprazole on gastric and lower esophageal sphincter muscle tissue." | 3.80 | Pantoprazole decreases gastroesophageal muscle tone in newborn rats via rho-kinase inhibition. ( Belik, J; Kasirer, MY; Pan, J; Shifrin, Y; Welsh, C, 2014) |
| " Inhibitory effect of nifedipine against cholinergic contractions, blunted in acetic acid-induced colitis, was also recovered in MC-treated rats." | 3.80 | Antispasmodic and myorelaxant effects of the flavoring agent methyl cinnamate in gut: potential inhibition of tyrosine kinase. ( Aragão, KS; Brito, TS; Cosker, F; Lahlou, S; Lima, FJ; Magalhães, PJ; Ribeiro-Filho, HV; Santos, AA; Silva, CM; Souza, MH, 2014) |
| " AKM significantly inhibited the increases in smooth muscle contraction induced by methoxyamine, carbachol and CaCl2." | 3.80 | Relaxant effects of Aike Mixture on isolated bladder and prostatic urethral smooth muscle of rabbits. ( Cheng, WJ; Li, ZW; Lin, X; Shi, YL; Zhang, MJ, 2014) |
| " Carbachol (CCh) stimulated phosphatidylinositol (PI) hydrolysis, Rho kinase and zipper-interacting protein (ZIP) kinase activity, induced myosin phosphatase 1 (MYPT1) phosphorylation (at Thr(696)) and 20-kDa myosin light chain (MLC20) phosphorylation (at Ser(19)) and muscle contraction, and inhibited cAMP formation." | 3.79 | Differential regulation of muscarinic M2 and M3 receptor signaling in gastrointestinal smooth muscle by caveolin-1. ( Al-Shboul, O; Bhattacharya, S; Grider, JR; Mahavadi, S; Murthy, KS; Rajagopal, S, 2013) |
| " The effect of SS or normal immunoglobulin G (IgG) on smooth muscle (SM) motility was assessed by comparing the amplitude of carbachol (CCh) or electrical field stimulation (EFS) - induced muscle contraction before and after IgG application." | 3.79 | The inhibitory effects of antimuscarinic autoantibodies in the sera of primary Sjogren syndrome patients on the gastrointestinal motility. ( Jackson, MW; Park, K; Park, S, 2013) |
| "Inhalation of JMF2-1, an analog of lidocaine with reduced anesthetic activity, prevents airway contraction and lung inflammation in experimental asthma models." | 3.78 | Two for one: cyclic AMP mediates the anti-inflammatory and anti-spasmodic properties of the non-anesthetic lidocaine analog JMF2-1. ( Coelho, LP; Cordeiro, RS; da Costa, JC; Martins, MA; Olsen, PC; Silva, PM, 2012) |
| "To investigate a possible relation between hypercholesterolemia and detrusor smooth muscle function, we studied the contractile response to potassium challenge, carbachol (CCh), and the components of CCh-induced contractile mechanism in high-cholesterol diet-fed rats." | 3.78 | The effect of hypercholesterolemia on carbachol-induced contractions of the detrusor smooth muscle in rats: increased role of L-type Ca2+ channels. ( Balkanci, ZD; Bayrak, S; Erdem, A; Karabulut, I; Karaismailoğlu, S; Pehlivanoğlu, B, 2012) |
| " Metformin treatment improved the insulin sensitivity, and normalized the in vitro bladder hypercontractility and cystometric dysfunction in obese mice." | 3.78 | Role of PKC and CaV1.2 in detrusor overactivity in a model of obesity associated with insulin resistance in mice. ( Anhê, GF; Antunes, E; Calixto, MC; De Nucci, G; Grant, AD; Leiria, LO; Lintomen, L; Mónica, FZ; Sollon, C; Zanesco, A, 2012) |
| " Activation of G(q) protein-coupled receptors, such as muscarinic M(3) and histamine H(1) receptors, induces smooth muscle contraction through activation of voltage-dependent Ca channels." | 3.77 | Desensitization of depolarization-mediated contractile pathways does not necessarily regulate receptor-mediated excitation-contraction coupling in longitudinal smooth muscle of guinea pig ileum. ( Hishinuma, S; Shoji, M, 2011) |
| " To address these knowledge deficits, and in particular to test the hypothesis that Ca2+ sensitization via activation of the RhoA/Rho-associated kinase (ROK) pathway plays an important role in ureteric smooth muscle contraction, we carried out a thorough characterization of the electrical activity, Ca2+ signaling, MYPT1 (myosin targeting subunit of myosin light chain phosphatase, MLCP) and myosin regulatory light chain (LC20) phosphorylation, and force responses to membrane depolarization induced by KCl (electromechanical coupling) and carbachol (CCh) (pharmacomechanical coupling)." | 3.77 | The importance of Rho-associated kinase-induced Ca2+ sensitization as a component of electromechanical and pharmacomechanical coupling in rat ureteric smooth muscle. ( Borysova, L; Burdyga, T; Shabir, S; Walsh, MP, 2011) |
| "According to tests, carbachol, in concentrations ranging between 10(-8) M to 10(-4) M, in a dosage-dependent way induces gastric fundus smooth muscle contraction." | 3.77 | Role of M1 receptor in regulation of gastric fundus smooth muscle contraction. ( Gajdus, M; Glaza, I; Olkowska, J; Szadujkis-Szadurska, K; Szadujkis-Szadurski, L; Szadujkis-Szadurski, R, 2011) |
| " Key Results In rat ileal smooth muscle, phosphorylation level of CPI-17 at Thr(38) and MYPT1 at Thr(853) , but not MYPT1 at Thr(696) , were increased with carbachol (1μmolL(-1) ) accompanied with muscle contraction." | 3.77 | Synchronous phosphorylation of CPI-17 and MYPT1 is essential for inducing Ca(2+) sensitization in intestinal smooth muscle. ( Hori, M; Kishi, H; Kobayashi, S; Mori, D; Murata, T; Ohama, T; Ozaki, H, 2011) |
| " In this study we examine the expression and function of FIZZ1 in an ovalbumin mouse model of asthma." | 3.76 | FIZZ1 potentiates the carbachol-induced tracheal smooth muscle contraction. ( Bowman, MR; Chen, H; Jacobson, BA; Mason, L; Wolf, SF, 2010) |
| "To investigate the effect of curcumin on colitis-induced reduction of carbachol-induced contraction in colon segments from rats treated with trinitrobenzenesulphonic acid." | 3.75 | Curcumin reverses attenuated carbachol-induced contraction of the colon in a rat model of colitis. ( Khan, I; Lubbad, AS; Oriowo, MA, 2009) |
| "Ascorbic acid and citric acid augmented bladder muscle contraction possibly by enhanced Ca(2+) influx." | 3.75 | Modification of rat detrusor muscle contraction by ascorbic acid and citric acid involving enhanced neurotransmitter release and Ca2+ influx. ( Dasgupta, J; Elliott, RA; Tincello, DG, 2009) |
| "Prostate samples, obtained from male Wistar rats and 8 patients undergoing endoscopic surgery for benign prostatic hyperplasia, were studied by measurement of isometric contraction induced by electrical field stimulation (EFS), noradrenalin, carbachol, serotonin and ATP, in the presence or absence of amikacin 10(-3) M in a low-Ca medium." | 3.74 | Inhibition of prostate efferent neurotransmission by amikacin. ( Bassi, P; Gardi, M; Nigro, F; Pinto, F; Ragazzi, E; Sacco, E; Totaro, A; Volpe, A, 2008) |
| " Since amikacin was reported to affect neurotransmission by a prejunctional mechanism, we investigated the effect of amikacin on isolated detrusor smooth muscle contraction to further evaluate its potential relaxant properties." | 3.74 | In vitro effect of amikacin on rat and human detrusor muscle contraction. ( Bassi, P; Gardi, M; Nigro, F; Pinto, F; Ragazzi, E; Sacco, E; Totaro, A; Volpe, A, 2008) |
| "To determine the efficacy of coenzyme Q10 (CoQ10) and alpha-lipoic acid (alpha-LA), either alone or in combination, to protect the contractile responses of the rabbit urinary bladder from damage caused by repetitive stimulation in the presence or absence of in vitro ischemia." | 3.74 | Effect of co-enzyme Q10 and alpha-lipoic acid on response of rabbit urinary bladder to repetitive stimulation and in vitro ischemia. ( Levin, RM; Lin, WY; Rehfuss, A; Schuler, C, 2008) |
| "To investigate the effects of menthol, an activator of the temperature-sensitive transient receptor potential family member TRPM8, on detrusor smooth-muscle contraction and the micturition reflex in rats." | 3.74 | Effect of menthol on detrusor smooth-muscle contraction and the micturition reflex in rats. ( Harada, K; Ikeda, S; Kamikawa, Y; Kawahira, K; Nomoto, Y; Ohwatashi, A; Yoshida, A, 2008) |
| " Furthermore, the effects of eviprostat on carbachol-induced muscle contraction were evaluated by an in vitro experiment." | 3.74 | Effect of eviprostat on bladder overactivity in an experimental cystitis rat model. ( Fujimoto, N; Kobayashi, M; Matsumoto, S; Matsumoto, T; Nishii, H; Nomura, M, 2008) |
| "Ryanodine receptors (RyRs), intracellular calcium release channels essential for skeletal and cardiac muscle contraction, are also expressed in various types of smooth muscle cells." | 3.73 | Ryanodine receptors in muscarinic receptor-mediated bronchoconstriction. ( Du, W; Eu, JP; Meissner, G; Rosenberg, PB; Stiber, JA, 2005) |
| " The metabolite showed to some extent mydriatic effect and protective effect against carbachol-induced bradycardia, but of much shorter durations than glycopyrrolate; it had, however, no effect on resting heart rate." | 3.73 | Pharmacokinetic and pharmacodynamic evaluations of the zwitterionic metabolite of a new series of N-substituted soft anticholinergics. ( Bodor, N; Buchwald, P; Ji, F; Mori, N; Wu, J; Wu, WM, 2005) |
| " ANP did not affect receptor-dependent and receptor-independent gastric muscle contractions except the contractions to substance P, which were slightly inhibited." | 3.73 | Regional differences in gastrointestinal motility disturbances during acute necrotising pancreatitis. ( De Man, JG; De Winter, BY; Herman, AG; Pelckmans, PA; Seerden, TC; Van Den Bossche, RM, 2005) |
| " Application of carbacholine (CCh) in vitro in different concentrations led to pronounced muscle contractions, varying from 9." | 3.73 | Different effects of ATP on the contractile activity of mice diaphragmatic and skeletal muscles. ( Burnstock, G; Devyataev, AM; Galkin, AV; Grishin, SN; Mukhamedyarov, MA; Palotás, A; Teplov, AY; Zefirov, AL; Ziganshin, AU, 2006) |
| " ATP significantly increased the strength of muscle contraction induced by carbachol." | 3.73 | Role of protein kinase C in the effect of ATP on contractile function of the isolated strip from mouse diaphragm. ( Grishin, SN; Teplov, AY; Zefirov, AL; Ziganshin, AU, 2006) |
| " To explore roles of intracellular Ca(2+) stores in excitation-contraction coupling in smooth muscle, we examined the effects of ryanodine, a fixer of ryanodine receptor-Ca(2+) channels to an open state, and thapsigargin, a selective inhibitor of the Ca(2+) pump in the intracellular stores, on smooth muscle contraction in the presence and absence of extracellular Ca(2+) in guinea-pig taenia caeci." | 3.73 | Differential roles of ryanodine- and thapsigargin-sensitive intracellular CA2+ stores in excitation-contraction coupling in smooth muscle of guinea-pig taenia caeci. ( Hishinuma, S; Saito, M, 2006) |
| "Droperidol attenuates airway smooth muscle contraction." | 3.72 | Droperidol attenuates contractile and phosphatidylinositol responses of rat trachea. ( Makita, T; Morooka, H; Saito, M; Shibata, O; Sumikawa, K, 2003) |
| " Smooth muscle relaxation was obtained by salbutamol and l-phenylephrine, whereas contraction was achieved by carbachol and 1-(3-chlorophenyl)-biguanide." | 3.72 | Effect of pharmacologically induced smooth muscle activation on permeability in murine colitis. ( Garrelds, IM; Meijssen, MA; van Meeteren, ME; Zijlstra, FJ, 2003) |
| "1 - 100 microM) inhibited carbachol- and high K +-induced muscle contractions in a concentration-dependent fashion, but did not affect basal muscle tension." | 3.72 | Inhibition of smooth muscle contraction by magnolol and honokiol in porcine trachea. ( Chan, MH; Chen, HH; Ko, CH; Lin, YR, 2003) |
| "To test the hypothesis that the changes in ileal smooth muscle contractility accompanying postgastrectomy syndromes are agonist-specific, we investigated the effects of potassium chloride (KCl), carbachol, substance P (SP), and serotonin on ileal smooth muscle contractility after total gastrectomy in rats." | 3.72 | Altered contractile responsiveness in ileal longitudinal muscle after total gastrectomy in a rat model. ( Gokgoz, S; Gursoy, S; Kaya, T; Koyluoglu, G; Saraydin, S; Sen, M, 2004) |
| " Peptides corresponding to the second extracellular loop of the M3R were used as immunogens in rabbits, and antisera were tested for inhibition of carbachol-evoked colon smooth muscle contraction in parallel with immunoglobulin G from a patient with SS." | 3.72 | Antibodies raised against the second extracellular loop of the human muscarinic M3 receptor mimic functional autoantibodies in Sjögren's syndrome. ( Cavill, D; Gordon, TP; Waterman, SA, 2004) |
| " This study investigates the effect of erythromycin on rat detrusor muscle contractile response to characterise its potential as an alternative inhibitor of bladder muscle contraction." | 3.72 | Direct inhibition of rat detrusor muscle contraction by erythromycin. ( Elliott, RA; England, RC; Norman, RI, 2004) |
| " We used video microscopy to study the contractility of circular smooth muscle cells (CSMC) isolated from the rat mid-descending colon throughout the course of TNBS-induced colitis, measuring their shortening response to carbachol (CCh), 5-HT, histamine or high K(+)." | 3.72 | Persistent and selective effects of inflammation on smooth muscle cell contractility in rat colitis. ( Blennerhassett, MG; Wells, RW, 2004) |
| "To clarify whether cyclic AMP (cAMP)/cAMP-dependent protein kinase (PKA) activation and Rho-kinase inhibition share a common mechanism to decrease the Ca2+ sensitivity of airway smooth muscle contraction, we examined the effects of 8-bromoadenosine 3',5'-cyclic monophosphate (8-BrcAMP), a stable cAMP analog, and (+)-(R)-trans-4-(1-aminoethyl)-N-(4-pyridyl) cyclohexane carboxamide dihydrochloride, monohydrate (Y-27632), a Rho-kinase inhibitor, on carbachol (CCh)-, guanosine 5'-O-(3-thiotriphosphate) (GTPgammaS)-, 4beta-phorbol 12,13-dibutyrate (PDBu)-, and leukotriene D4 (LTD4)-induced Ca2+ sensitization in alpha-toxin-permeabilized rabbit tracheal and human bronchial smooth muscle." | 3.72 | 8-Bromo-cAMP decreases the Ca2+ sensitivity of airway smooth muscle contraction through a mechanism distinct from inhibition of Rho-kinase. ( Dobashi, K; Endou, K; Iizuka, K; Ishizuka, T; Mori, M; Nakazawa, T; Tsukagoshi, H; Yoshii, A, 2004) |
| " Furthermore, DNP inhibited carbachol-induced muscle contraction, suggesting that it also can modulate the nerve regulation of colonic motility." | 3.72 | Dendroaspis natriuretic peptide system and its paracrine function in rat colon. ( Kim, JH; Kim, SH; Kim, SY; Lee, HK; Yang, SH; Yu, MY, 2004) |
| "These results strongly suggest that impaired endothelium dependent and NO mediated cavernous relaxation with aging is due to decreased NO production, which would result from increased arginase activity and probably from decreased L-arginine content." | 3.72 | Involvement of increased arginase activity in impaired cavernous relaxation with aging in the rabbit. ( Azuma, H; Kihara, K; Kurosaki, E; Masuda, H; Sakai, Y; Yamauchi, Y, 2004) |
| "The results showed that Kohki Tea pretreatment protected the bladder's response to FS from the detrimental effects of repetitive stimulation and the detrimental effects of both in vitro ischemia and repetitive stimulation on the contractile responses to carbachol and KCl." | 3.72 | Oral Kohki Tea and its protective effect against in vitro ischemic damage to the bladder. ( Aikawa, K; Kambara, T; Leggett, RE; Levin, RM; Murakami, T; Whitbeck, C, 2004) |
| "The contraction responses to carbachol and histamine and relaxation responses to COX inhibitors on gallbladder smooth muscle are significantly decreased by peritonitis." | 3.72 | Effect of peritonitis on gallbladder smooth muscle contractility in guinea pigs. ( Bagcivan, I; Ceran, C; Gökgöz, S; Karadas, B; Kaya, TT; Koyluoglu, G; Yildiz, T, 2004) |
| "In the pulmonary artery isolated from 1-week hypoxia-induced pulmonary hypertensive rats, endothelial NO production stimulated by carbachol was decreased significantly in in situ visualization using diaminofluorescein-2 diacetate and also in cGMP content." | 3.71 | Decreased endothelial nitric-oxide synthase (eNOS) activity resulting from abnormal interaction between eNOS and its regulatory proteins in hypoxia-induced pulmonary hypertension. ( Hori, M; Karaki, H; Murata, T; Ozaki, H; Sato, K, 2002) |
| "The aim of this study was to determine the effects of nimesulide and pentoxifylline on the contractile effects of KCl, carbachol and substance P in the longitudinal muscle of rat ileum during peritonitis." | 3.71 | Effects of nimesulide and pentoxifylline on decreased contractile responses in rat ileum with peritonitis. ( Arpacik, M; Karadas, B; Kaya, TT; Koyluoglu, G; Soydan, AS, 2002) |
| " The aim of this study was to determine the effects of peritonitis on longitudinal ileum smooth muscle responses to KCl, carbachol and substance P (SP) and to examine the role of nitric oxide (NO) and N(omega)-nitro-L-arginine methylester (L-NAME) on ileal contractility in this peritonitis model." | 3.71 | Effect of L-NAME on decreased ileal muscle contractility induced by peritonitis in rats. ( Bagcivan, I; Kaya, T; Köylüoğlu, G; Yildiz, T, 2002) |
| " Oh9-1 inhibited carbachol-induced muscle contraction in an irreversible manner and the dose for achieving 50% inhibition was approximately fourfold that of alpha-bungarotoxin." | 3.71 | Purification and characterization of a neurotoxin from the venom of Ophiophagus hannah (king cobra). ( Chang, LS; Huang, HB; Lin, SR; Liou, JC, 2002) |
| "Effects of 1-hour in vitro ischemia on rabbit corporal tissue were as follows: (1) an 85% decrease in contractile response to phenylephrine, and (2) a marked increase in rate of contractile response to phenylephrine." | 3.70 | Digital analysis of the pharmacological effects of in vitro ischemia on rabbit corpus cavernosum. ( Horan, P; Levin, RM; Liu, SP, 1998) |
| "The effects of repetitive and nonrepetitive FS on the contractile responses of isolated strips of rabbit bladder to FS, carbachol, and KCl were determined in the presence of 3 different incubation media: O2 + glucose (normal physiological medium); N2 + glucose (in vitro hypoxia), and N2 - glucose (in vitro ischemia)." | 3.70 | Effect of repetitive stimulation on the contractile response of rabbit urinary bladder subjected to in vitro hypoxia or in vitro ischemia followed by reoxygenation. ( Horan, P; Levin, RM; Liu, SP; Ohnishi, N, 1998) |
| "We examined the bladder function of cystitis models induced by intravesical acetone instillation in urethane-anesthetized rats." | 3.70 | Urodynamics in acetone-induced cystitis of anesthetized rats. ( Hosoki, K; Kawashima, K; Shimizu, I, 1999) |
| "We investigated the mechanism of mucosal modulation of airway smooth muscle contraction by measuring concentration- and length dependencies of carbachol-induced active stress and myosin phosphorylation in mucosa-intact and mucosa-free bovine tracheal smooth muscle." | 3.70 | Mucosal modulation of agonist-induced myosin phosphorylation and contraction in airway smooth muscle. ( Hai, CM; Wong, CT, 1999) |
| "Pretreatment with propofol shifts the concentration-response curves of carbachol-induced smooth muscle contraction to the right in a concentration-dependent manner without changing the maximal response." | 3.70 | Mechanisms underlying the inhibitory effect of propofol on the contraction of canine airway smooth muscle. ( Chien, CS; Chiu, CT; Lin, CC; Pan, SL; Shyr, MH; Tan, PP; Wang, CC; Yang, CM, 1999) |
| "We investigated the direct interaction between the volatile anesthetics, isoflurane and sevoflurane, and hypoxia in porcine tracheal smooth muscle in vitro by simultaneously measuring muscle tension and intracellular concentration of free Ca(2+) ([Ca2+]i)." | 3.70 | Interaction between volatile anesthetics and hypoxia in porcine tracheal smooth muscle. ( Chen, X; Kamada, Y; Namiki, A; Tsujiguchi, N; Yamakage, M, 2000) |
| "Instillation of amlexanox, an anti-allergic drug, over a long period improves myopia in some allergy patients and in monkeys." | 3.70 | Inhibitory effects of amlexanox on carbachol-induced contractions of rabbit ciliary muscle and guinea-pig taenia caecum. ( Gomi, Y; Mizutani, K; Ogawa, T; Tominaga, Y; Tsunobuchi-Ushijima, H; Watanabe, N, 2000) |
| ", ANP, ANP fragments, VIP, secretin, and peptide histidine isoleucine); the effect of ANP, ANP fragments, and VIP on muscle contraction stimulated by 1 mumol/L carbachol was assessed; and the inhibitory effects of ANP 1-11 on VIP-induced relaxation, ANP 1-11 and VIP 10-28 (a VIP antagonist) on ANP-induced relaxation, and nitric oxide production inhibitors on ANP-induced relaxation were assessed." | 3.69 | Interaction between atrial natriuretic peptide and vasoactive intestinal peptide in guinea pig cecal smooth muscle. ( Akiho, H; Chijiiwa, Y; Harada, N; Nawata, H; Okabe, H, 1995) |
| "Sodium nitroprusside inhibited carbachol-induced contractions of the iris sphincter muscle in a concentration-dependent manner but had no effect on neurokinin A-induced muscle contractions." | 3.69 | Nitric oxide-sensitive and -insensitive contractions of the isolated rabbit iris sphincter muscle. ( Chuman, H; Chuman, T; Nao-i, N; Sawada, A; Wada, A; Yamamoto, R, 1996) |
| "Urinary bladder smooth muscle contraction can be evaluated using field stimulation (neurohumoral transmission), carbachol (muscarinic stimulation), and KCl (direct membrane depolarization)." | 3.69 | Physiological effects of a novel bioactive agent. ( Geloso, D; Hass, MA; Horan, P; Leggett, RE; Levin, RM, 1996) |
| "The present study investigated the mechanisms of melatonin-induced inhibition of the ileal smooth muscle contraction." | 3.69 | Apamin blocks the direct relaxant effect of melatonin on rat ileal smooth muscle. ( García-Segoviano, JA; Naranjo-Rodríguez, EB; Prieto-Gómez, B; Reyes-Vázquez, C; Trujillo-Santana, JT, 1997) |
| "To evaluate the cellular mechanisms involved in hypoxic relaxation of airway smooth muscle, we investigated the effects of hypoxia on the behavior of third- and fourth-order porcine bronchial rings contracted with either carbachol or KCl." | 3.68 | Role of Ca2+ entry in the modulation of airway tone by hypoxia. ( Croxton, TL; Fernandes, LB; Hirshman, CA; Stuart-Smith, K, 1993) |
| " Muscarinic stimulation of isolated, preconstricted segments of the basilar artery, with either acetylcholine or carbachol, was followed by endothelium-dependent smooth muscle relaxation and membrane hyperpolarization." | 3.68 | Endothelium-dependent relaxation to acetylcholine in the rabbit basilar artery: importance of membrane hyperpolarization. ( Garland, CJ; Rand, VE, 1992) |
| "The effect of the calcium antagonists omega-conotoxin GVIA, verapamil, gallopamil and diltiazem was investigated on in vitro bronchial smooth muscle contraction in the rat induced by the nerve agent soman." | 3.68 | Effect of calcium antagonists (omega-conotoxin GVIA, verapamil, gallopamil, diltiazem) on bronchial smooth muscle contractions induced by soman. ( Aas, P; Fyllingen, E; Walday, P, 1992) |
| " The effects of endothelin-1 (ET-1) and of the muscarinic cholinoceptor agonist, carbachol, on [3H]-inositol phosphate ([3H]-InsP) accumulation and smooth muscle contraction were determined in rat isolated tracheal tissue." | 3.68 | Endothelin-1-induced [3H]-inositol phosphate accumulation in rat trachea. ( Goldie, RG; Henry, PJ; Preuss, JM; Rigby, PJ; Self, GJ, 1992) |
| " The effects of haloperidol on smooth muscle contraction induced by carbachol, histamine, high K or caffeine in the presence or absence of extracellular Ca were investigated." | 3.68 | Haloperidol differentiates smooth muscle contractions induced by release of intracellularly stored Ca and by influx of extracellular Ca. ( Hishinuma, S; Hongo, I; Kurokawa, M; Uchida, MK, 1992) |
| "The effect of a cyclic GMP phosphodiesterase inhibitor, M & B 22948, on carbachol-induced phosphatidylinositol 4,5-bis-phosphate (PIP2) breakdown and phosphatidic acid labeling, 1,4,5-inositol trisphosphate (IP3) accumulation and muscle contraction was studied in bovine iris sphincter smooth muscle." | 3.68 | The effect of M & B 22948 on carbachol-induced inositol trisphosphate accumulation and contraction in iris sphincter smooth muscle. ( Abdel-Latif, AA; Akhtar, RA, 1991) |
| "The present study examined 15 patients previously resistant to conventional antihistamines, in which doxepin at doses in the range of 50-75 mg/day was shown to be effective in treatment of chronic urticaria and without significant adverse side effects." | 3.68 | Mechanism of action of doxepin in the treatment of chronic urticaria. ( Almeida, L; Figueiredo, A; Gonçalo, M; Poiares-Baptista, A; Ribeiro, CA; Teixeira, F, 1990) |
| "To determine the muscarinic receptor subtype mediating guinea pig ileal mucosal electrolyte secretion, we compared the potencies (Kb) of selective M1 (pirenzepine) (PZ), M2 (AF-DX 116, methoctramine), and M3 [4-diphenylacetoxy-N-methylpiperidine methiodide (4-DAMP), hexahydrosiladifenidol (HHSiD)] antagonists as inhibitors of carbachol-induced reductions in guinea pig atrial heart rate and ileal longitudinal muscle contractions, responses mediated by M2 and M3 receptors, respectively." | 3.68 | Regulation of guinea pig ileal electrolyte transport by M3-muscarinic acetylcholine receptors in vitro. ( Gaginella, TS; Kachur, JF; Noronha-Blob, L; Sturm, BL, 1990) |
| "A series of tertiary 3- and 4-haloalkylamines related to the muscarinic agent oxotremorine was synthesized." | 3.67 | Tertiary 3- and 4-haloalkylamine analogues of oxotremorine as prodrugs of potent muscarinic agonists. ( Jenden, DJ; Ringdahl, B; Roch, M, 1988) |
| "The temporal relationship between release of the mediators histamine and slow reacting substance of anaphylaxis (SRS-A) and smooth muscle contraction in response to antigen was examined using superfused tracheae from actively sensitized (ovalbumin) and reserpine-pretreated guinea pigs." | 3.67 | Studies on the relationship between contraction and mediator release produced by ovalbumin in superfused trachea isolated from the actively sensitized guinea pig. ( Buckner, CK; Fishleder, RI, 1984) |
| " Three of the most potent antagonists were tested for specificity and found to block the smooth muscle contraction induced by SP, physalaemin, eledoisin and bombesin but not that induced by bradykinin, carbachol, 5-hydroxytryptamine, histamine, prostaglandins and vasopressin." | 3.67 | Biological evaluation of substance P antagonists. ( Folkers, K; Håkanson, R; Hörig, J; Leander, S; Xu, JC, 1984) |
| "Rat calcitonin gene-related peptide (rat CGRP) and related peptides did not cause contraction of gastric smooth muscle cells; however, preincubation with rat CGRP or human CGRP inhibited smooth muscle contraction caused by carbachol." | 3.67 | Characterization of receptors for calcitonin gene-related peptide on gastric smooth muscle cells. ( Collins, SM; Gardner, JD; Jensen, RT; Maton, PN; Sutliff, VE; Zhou, ZC, 1988) |
| "The enantiomers of three 5-methyl-2-pyrrolidone analogues of the muscarinic agent oxotremorine (1) were synthesized." | 3.67 | Stereoselectivity of muscarinic receptors in vivo and in vitro for oxotremorine analogues. N-[4-(tertiary amino)-2-butynyl]-5-methyl-2-pyrrolidones. ( Amstutz, R; Jenden, DJ; Karlén, B; Ringdahl, B; Roch, M, 1985) |
| "1 microM Ca++; and phorbol 12,13-dibutyrate, but not phorbol 12-myristate 13-acetate, induced MLC phosphorylation and muscle contraction in a dose- and time-dependent manner." | 3.67 | Correlative studies on the effect of carbachol on myo-inositol trisphosphate accumulation, myosin light chain phosphorylation and contraction in sphincter smooth muscle of rabbit iris. ( Abdel-Latif, AA; Akhtar, RA; Howe, PH; Naderi, S, 1986) |
| "Micturition and bladder responsiveness in vitro were impaired in rats fed isotonic sucrose, afflicted with diabetes mellitus or diabetes insipidus." | 3.66 | Impairment and restoration of rat urinary bladder responsiveness following distension. ( Carpenter, FG, 1983) |
| " 5 Specific doses of atropine, mepyramine (H1-blocker) and methysergide (5-HT antagonist) did not modify the anaphylactic reaction in coronary arteries, suggesting a negligible role for these biogenic amines." | 3.66 | Coronary anaphylaxis in vitro. ( Chand, N; Eyre, P, 1979) |
| "Cyclic nucleotide levels and tension were measured at various times during carbachol-induced smooth muscle contractions." | 3.65 | Cyclic nucleotide levels during carbachol-induced smooth muscle contractions. ( Hartle, DK, 1976) |
| "Muscle strips from the body and neck of the gallbladder were suspended in organ baths and dose-response curves were constructed for CCK-8 and carbachol." | 2.69 | In vitro responses of gallbladder muscle from patients with acalculous biliary pain. ( Ahmed, R; Bird, NC; Chess-Williams, R; Johnson, AG; Thomas, WE, 2000) |
| "Metabolic syndrome was induced in rats by high-fat and high-carbohydrate diet." | 1.72 | Airway Smooth Muscles Contractions in Metabolic Syndrome. ( Birulina, YG; Buiko, EE; Dzyuman, AN; Gusakova, SV; Ivanov, VV; Nosarev, AV; Vol'khina, MO; Voronkova, OV, 2022) |
| "Chlorogenic acid (CGA) is a polyphenol found in coffee and medicinal herbs such as Lonicera japonica." | 1.48 | Effects of chlorogenic acid on carbachol-induced contraction of mouse urinary bladder. ( Kaneda, T; Sasaki, N; Shimizu, K; Urakawa, N, 2018) |
| "Interstitial cystitis is a syndrome characterized by detrusor overactivity and chronic inflammation of the bladder." | 1.48 | Rho Kinase and Protein Kinase C Pathways are Responsible for Enhanced Carbachol Contraction in Permeabilized Detrusor in a Rat Model of Cystitis. ( Bozkurt, TE; Denizalti, M; Durlu-Kandilci, NT; Sahin-Erdemli, I; Simsek, G, 2018) |
| "To create an animal model for neurogenic underactive bladder disease (UAB) and identify markers to describe secondary myogenic changes in the bladder wall." | 1.48 | Characterization of voiding function and structural bladder changes in a rat model of neurogenic underactive bladder disease. ( Albersen, M; Bivalacqua, TJ; De Ridder, D; Deruyer, Y; Dewulf, K; Everaerts, W; Rietjens, R; Van der Aa, F; Weyne, E, 2018) |
| "Mirabegron didn't produce significant inhibitory effects in any of the contractile elements in either species." | 1.43 | The actions of isoprenaline and mirabegron in the isolated whole rat and guinea pig bladder. ( De Wachter, S; Eastham, J; Gillespie, J; Persyn, S; Wyndaele, JJ, 2016) |
| "Carbachol was also used to increase the tone in trachea, bronchus rings and bladder strips." | 1.42 | Contractile function of smooth muscle retained after overnight storage. ( Lim, KH; Loong, BJ; Mbaki, Y; Tan, JH; Ting, KN, 2015) |
| "These symptoms are similar to the overactive bladder syndrome." | 1.40 | Izalpinin from fruits of Alpinia oxyphylla with antagonistic activity against the rat bladder contractility. ( Chen, F; Chen, WY; Huang, GJ; Li, H; Li, YH; Tan, YF; Xu, P; Yuan, Y; Zhang, JQ, 2014) |
| "The carbachol response was unaffected in the M2KO strain but decreased 42% in M3KO mice (p < 0." | 1.39 | Gastric body cholinergic contractile signal transduction in M2 and M3 receptor knockout mice. ( Braverman, AS; Ruggieri, MR, 2013) |
| "Acrylamide (ACR) is a chemical used in many industries around the world and more recently was found to be formed naturally in foods cooked at high temperatures." | 1.39 | Responses of acrylamide-treated rat bladders. ( Belviranli, M; Celik, I; Esen, H; Nurullahoglu-Atalik, E; Okudan, N; Yener, Y, 2013) |
| "Colitis was induced in BALB/c mice by provision of 5% dextran sodium sulfate (DSS) for 7 days." | 1.38 | The contribution of protein kinase C and CPI-17 signaling pathways to hypercontractility in murine experimental colitis. ( Chappellaz, M; Ihara, E; MacDonald, JA; Turner, SR, 2012) |
| "Bladder outlet obstruction was created by placement of a silver jeweler's jump rings loosely round the urethro-vesical junction of Guinea pigs." | 1.38 | Obstruction enhances rho-kinase pathway and diminishes protein kinase C pathway in carbachol-induced calcium sensitization in contraction of α-toxin permeabilized guinea pig detrusor smooth muscle. ( Kajioka, S; Matsuda, M; Naito, S; Onimaru, M; Seki, N; Shahab, N; Takahashi-Yanaga, F, 2012) |
| "Netupitant has clinical potential in conditions such as chemotherapy induced nausea and vomiting, in which the blockade of NK(1) receptors has been demonstrated valuable for patients." | 1.38 | In vitro and in vivo pharmacological characterization of the novel NK₁ receptor selective antagonist Netupitant. ( Calo', G; Camarda, V; Campi, B; Cantoreggi, S; Molinari, S; Pietra, C; Regoli, D; Rizzi, A, 2012) |
| "Colitis was induced in male Sprague-Dawley rats by intra-rectal instillation of trinitrobenzenesulphonic acid (TNBS)." | 1.38 | Expression of alternatively spliced variants of Na-Ca-exchanger-1 in experimental colitis: role in reduced colonic contractility. ( Khan, I; Oriowo, MA; Shubair, M, 2012) |
| "Pretreatment with curcumin caused a remarkable decrease in histopathological parameters such as edema, congestion and inflammatory cells." | 1.38 | Role of curcumin in mesenteric ischemia - reperfusion injury in rats. ( Belviranli, M; Esen, H; Gokbel, H; Nurullahoglu-Atalik, KE; Okudan, N; Oz, M, 2012) |
| "Fibrosis was quantified using the NIS Elements BR 2." | 1.38 | Gut fibrosis with altered colonic contractility in a mouse model of scleroderma. ( Denton, CP; Derrett-Smith, EC; Dooley, A; Khan, K; Shi-Wen, X; Thoua, NM, 2012) |
| "K+, carbachol (CCh) and ATP were used as contractile stimuli on rat detrusor strips with and without MU." | 1.38 | Variations in carbachol- and ATP-induced contractions of the rat detrusor: effects of gender, mucosa and contractile direction. ( Leung, PC; Liang, W, 2012) |
| "Indicaxanthin effects were reduced significantly in the presence of 3-isobutyl-1-methylxanthine (IBMX), a non selective inhibitor of phosphodiesterases (PDEs)." | 1.37 | Inhibitory effects of indicaxanthin on mouse ileal contractility: analysis of the mechanism of action. ( Baldassano, S; Livrea, MA; Mulè, F; Rotondo, A; Serio, R; Tesoriere, L, 2011) |
| "Carbachol did not cause contraction but instead caused relaxation of colonic strips from M(2)/M(3)R-KO mice." | 1.37 | Muscarinic receptor subtypes involved in regulation of colonic motility in mice: functional studies using muscarinic receptor-deficient mice. ( Kitazawa, T; Komori, S; Kondo, T; Nakajima, M; Teraoka, H; Unno, T; Yamada, M, 2011) |
| "Partial bladder outlet obstruction (PBOO), a common urologic pathology mostly caused by benign prostatic hyperplasia, can coexist in 40-45% of patients with overactive bladder (OAB) and is associated with detrusor overactivity (DO)." | 1.37 | Blebbistain, a myosin II inhibitor, as a novel strategy to regulate detrusor contractility in a rat model of partial bladder outlet obstruction. ( DiSanto, ME; Seftel, A; Zhang, X, 2011) |
| "Hydrogen sulfide (H(2)S) has been shown to affect gastrointestinal (GI) motility and signaling in mammals and O(2)-dependent H(2)S metabolism has been proposed to serve as an O(2) 'sensor' that couples hypoxic stimuli to effector responses in a variety of other O(2)-sensing tissues." | 1.37 | Hydrogen sulfide (H₂S) and hypoxia inhibit salmonid gastrointestinal motility: evidence for H₂S as an oxygen sensor. ( DeLeon, ER; Dombkowski, RA; Gao, Y; Naylor, MG; Olson, KR; Shoemaker, E; Smith, M; Stoy, GF, 2011) |
| "To evaluate chronic hyperlipidemia on bladder function, we examined the functional and histological changes of the bladder in myocardial infarction-prone Watanabe Heritable Hyperlipidemic (WHHLMI) rabbits." | 1.36 | The effects of chronic hyperlipidemia on bladder function in myocardial infarction-prone Watanabe heritable hyperlipidemic (WHHLMI) rabbits. ( Masunaga, K; Nagata, T; Satoji, Y; Shiomi, M; Yoshida, M, 2010) |
| " Dose-response curves were obtained with increasing concentrations of the KCNQ((2-5)) selective positive modulator, retigabine or with the KCNQ((1-5)) negative modulator XE991." | 1.36 | Functional effects of the KCNQ modulators retigabine and XE991 in the rat urinary bladder. ( Rode, F; Rønn, LC; Sheykhzade, M; Svalø, J, 2010) |
| "Carbachol was then added to the organ bath and contraction responses were obtained." | 1.36 | Evaluation of urinary bladder function after acute spinal cord injury: an experimental study. ( Bağcivan, I; Durmuş, N; Eğilmez, R; Oztemür, Z; Saraç, B; Tezeren, G, 2010) |
| "Organ hypertrophy is often found to be associated with changes in the expression of caveolins and altered density of caveolae in the membrane." | 1.36 | Biochemical and functional correlates of an increased membrane density of caveolae in hypertrophic rat urinary bladder. ( Ekman, M; Shakirova, Y; Swärd, K; Uvelius, B, 2010) |
| "Carbachol contractions were inhibited by either H(2)O(2)/*OH/O(2) * or CPA/FCCP." | 1.35 | The effects of reactive oxygen species on calcium- and carbachol-induced contractile responses in beta-escin permeabilized rat bladder. ( Durlu-Kandilci, NT; Sahin-Erdemli, I, 2008) |
| "Carbachol was the more 'potent' stimulator in anterior smooth muscle strips, but again the differences between agonists were not statistically significant." | 1.35 | Comparisons of the responses of anterior and posterior human adult male bladder neck smooth muscle to in vitro stimulation. ( Bolton, JF; Sibley, GN; Whittlestone, TH, 2008) |
| "L-carnitine treatment restored the hyporesponsiveness of isoprenaline and the hyperresponsiveness of adenosine-elicited relaxation." | 1.35 | L-carnitine treatment partially restores urinary bladder function of streptozotocin diabetic rats. ( Gur, S; Irat, AM, 2008) |
| "Lidocaine can cause direct ASM relaxation by decreasing [Ca(2+)]i." | 1.35 | Effect of lidocaine on endothelin-1-mediated airway smooth muscle contraction in the rat trachea. ( Akhtar, S; Brull, SJ; Harrison, BA; Podgoreanu, M, 2008) |
| "Pretreatment with indomethacin at both concentrations did not result in a significant reduction in the maximum contraction compared with the control." | 1.35 | In vitro effects of the cyclooxygenase inhibitor indomethacin and of the phospholipase-C inhibitor U-73122 on carbachol-induced contractions of porcine detrusor muscle. ( Badawi, JK; Bross, S; Seja, T, 2008) |
| "Colitis was induced in BALB/c mice by providing 5% dextran sulfate sodium (DSS) in drinking water for 7 days." | 1.35 | Mitogen-activated protein kinase pathways contribute to hypercontractility and increased Ca2+ sensitization in murine experimental colitis. ( Beck, PL; Chappellaz, M; Ihara, E; MacDonald, JA; Medlicott, SA; Wong, J, 2009) |
| "Lubiprostone is shown to increase submucosal gland secretion in pigs, sheep, and humans and to increase short-circuit current (SCC) in the surface epithelium of pigs and sheep." | 1.35 | Lubiprostone stimulates secretion from tracheal submucosal glands of sheep, pigs, and humans. ( Cuthbert, AW; Joo, NS; Wine, JJ, 2009) |
| "Adenosine (10 microM) was used as other contractile agent for comparison." | 1.35 | Contribution of RhoA kinase and protein kinase C to weak relaxant effect of pinacidil on carbachol-induced contractions in sensitized guinea-pig trachealis. ( Gok, S; Izanli-Paksoy, A; Vural, K, 2009) |
| "We hypothesized that food allergy causes a state of non-specific jejunal dysmotility." | 1.35 | Food allergy alters jejunal circular muscle contractility and induces local inflammatory cytokine expression in a mouse model. ( Berstad, A; Eklund, KK; Kovanen, PT; Lappalainen, J; Lin, AH; Rita, H; Vaali, K; Valeur, J, 2009) |
| "Celiac disease is a gluten intolerance caused by a T-cell response against human leukocyte antigen (HLA)-DQ2 and DQ8-bound gluten peptides." | 1.35 | Gliadin-dependent neuromuscular and epithelial secretory responses in gluten-sensitive HLA-DQ8 transgenic mice. ( Blennerhassett, PA; David, CS; Huang, X; Lu, J; McKay, DM; Murray, JA; Natividad, J; Verdu, EF, 2008) |
| "Pretreatment with propiverine and tolterodine caused parallel shifts to the right of the concentration-response curves to carbachol." | 1.35 | Pharmacological effects of propiverine and its active metabolite, M-1, on isolated human urinary bladder smooth muscle, and on bladder contraction in rats. ( Inadome, A; Maeda, Y; Masunaga, K; Nagata, T; Satoji, Y; Sugiyama, Y; Ueda, S; Yoshida, M, 2008) |
| "Minoxidil did not inhibit the contractions at both examined concentrations except for a very small effect at 1 Hz." | 1.35 | Inhibitory effects of different ATP-sensitive potassium channel openers on electrically generated and carbachol-induced contractions of porcine and human detrusor muscle. ( Badawi, JK; Bross, S; Ding, A, 2008) |
| "Overactive bladder is a complex and widely prevalent condition, but little is known about its physiopathology." | 1.35 | Long-term nitric oxide deficiency causes muscarinic supersensitivity and reduces beta(3)-adrenoceptor-mediated relaxation, causing rat detrusor overactivity. ( Abdalla, FM; Antunes, E; Báu, FR; Bricola, AA; De Nucci, G; Freitas, LL; Mónica, FZ; Muscará, MN; Porto, CS; Teixeira, SA; Zanesco, A, 2008) |
| "Acquired urinary incontinence is a significant, incurable problem, prevalent in neutered bitches but rarely seen in entire bitches or males." | 1.35 | Neutering affects urinary bladder function by different mechanisms in male and female dogs. ( Coit, VA; Dowell, FJ; Evans, NP; Gibson, IF, 2008) |
| "In RTX-treated neurogenic bladders the amplitude and duration of autonomous contractions were increased compared with controls (P < 0." | 1.34 | Autonomous contractile activity in the isolated rat bladder is modulated by a TRPV1 dependent mechanism. ( De Ridder, D; Gevaert, T; Nilius, B; Ost, D; Vandepitte, J, 2007) |
| "To investigate the effects of anoxia and glucopenia (A-G) on both male and female guinea pig urinary bladder." | 1.34 | Gender-related neuronal and smooth muscle damage of guinea pig isolated urinary bladder from anoxia-glucopenia and reperfusion injury and its relationship to glycogen content. ( Dragoni, S; Pessina, F; Sgaragli, G; Valeri, A; Valoti, M, 2007) |
| "Pretreatment with atorvastatin caused remarkable decrease in both oxidative stress and neutrophil accumulation." | 1.34 | Attenuation of contractile dysfunction by atorvastatin after intestinal ischemia reperfusion injury in rats. ( Cetin, A; Igdem, AA; Ozacmak, ID; Ozacmak, VH; Sayan, H, 2007) |
| "An association between chronic renal failure (CRF) and gastroesophageal reflux (GER) is well known." | 1.34 | Effect of chronic renal failure on foregut smooth muscle reactivity: an experimental study. ( Tugay, M; Utkan, T; Yazir, Y; Yildiz, F, 2007) |
| "Carbachol was able to induce contractions of the prefilled bladder with a complete draining of the bladder throughout the whole perfusion period." | 1.34 | The extracorporeal perfusion of the female pig detrusor as an experimental model for the study of bladder contractility. ( Beckmann, MW; Dittrich, R; Hoffmann, I; Koelbl, H; Maake, C; Maltaris, T; Mueller, A; Mueller, S; Naumann, G; Oppelt, PG, 2007) |
| "Colitis was confirmed using gross morphology, histology, and measurements of myeloperoxidase activity." | 1.34 | Changes in urinary bladder smooth muscle function in response to colonic inflammation. ( Akbarali, H; Foreman, RD; Greenwood-Van Meerveld, B; Malykhina, A; Noronha, R, 2007) |
| "Male rabbits underwent surgical partial bladder outlet obstruction for durations of 1, 2, 4, and 8 weeks." | 1.34 | The effect of partial bladder outlet obstruction on carbonyl and nitrotyrosine distribution in rabbit bladder. ( Juan, YS; Kalorin, C; Kogan, BA; Levin, RM; Lin, WY; Mannikarottu, A, 2007) |
| "Bimatoprost is a synthetic analog of prostaglandin F(2 alpha) ethanolamide (prostamide F(2 alpha)), and shares a pharmacological profile consistent with that of the prostamides." | 1.33 | Bimatoprost and prostaglandin F(2 alpha) selectively stimulate intracellular calcium signaling in different cat iris sphincter cells. ( Chen, J; Krauss, AH; Nieves, AL; Protzman, CE; Sachs, G; Scott, DF; Spada, CS; Wheeler, LA; Woodward, DF, 2005) |
| " (c) Ethanol mediated a dose-response enhancement of the contractile dysfunctions caused by in vitro ischemia." | 1.33 | Effect of ethanol on the response of the rat urinary bladder to in vitro ischemia: protective effect of alpha-lipoic acid. ( Danek, M; Haugaard, N; Levin, RM; Whitbeck, C, 2005) |
| "Acute gastroenteritis is a strong risk factor for the development of irritable bowel syndrome (IBS)." | 1.33 | Mechanisms underlying the maintenance of muscle hypercontractility in a model of postinfective gut dysfunction. ( Akiho, H; Blennerhassett, P; Collins, SM; Deng, Y; Kanbayashi, H, 2005) |
| " For the total phospholipid fraction, increasing the dietary FO levels led to a significant increase first evident at 1% FO, with a stepwise, nonsaturating six-fold increase in n-3 PUFA as EPA (20:5n-3), DPA (docosapentaenoic acid, 22:5n-3), and DHA, but mainly as DHA (22:6n-3), replacing the n-6 PUFA linoleic acid (18:2n-6) and arachidonic acid (20:4n-6) over the dosage range." | 1.33 | Dietary fish oil dose-response effects on ileal phospholipid fatty acids and contractility. ( Abeywardena, MY; Adams, MJ; Dallimore, JA; Patten, GS, 2005) |
| "Pretreatment with glycycoumarin also enhanced the relaxation effect of rolipram, a specific inhibitor of PDE isozyme 4, as pretreatment with milrinone, a specific inhibitor of isozyme 3, did." | 1.33 | Glycycoumarin from Glycyrrhizae Radix acts as a potent antispasmodic through inhibition of phosphodiesterase 3. ( Akao, T; Asano, T; He, JX; Kuraishi, Y; Morota, T; Nojima, H; Sato, Y; Tani, T, 2006) |
| "Partial bladder outlet obstruction (PBOO) was produced by partial ligation of the urethra in New Zealand white rabbits." | 1.33 | Lipid signaling changes in smooth muscle remodeling associated with partial urinary bladder outlet obstruction. ( Chacko, S; Delaney, D; Hypolite, J; LaBelle, E; Wein, A; Zderic, S, 2006) |
| " Dose-response curves for carbachol revealed a lower peak response in new-born bladders compared with adults." | 1.33 | Developmental regulation of nerve and receptor mediated contractions of mammalian urinary bladder smooth muscle. ( Andersson, KE; Arner, A; Ekman, M, 2006) |
| "Partial bladder outlet obstruction of the pig is considered as a valuable preclinical model for evaluating the profile of compounds for the treatment of bladder overactivity." | 1.33 | Pharmacological characterization of urinary bladder smooth muscle contractility following partial bladder outlet obstruction in pigs. ( Brune, ME; Buckner, SA; Coghlan, M; Daza, A; Fey, TA; Gopalakrishnan, M; Milicic, I, 2006) |
| "Tegaserod treatment, which did not affect cholinergic contractions of tissues from low cholesterol fed animals, abrogated the increase caused by the high cholesterol diet." | 1.33 | Increased cholinergic contractions of jejunal smooth muscle caused by a high cholesterol diet are prevented by the 5-HT4 agonist--tegaserod. ( Mathison, R; Shaffer, E, 2006) |
| " At higher concentrations, 3 x 10(-5) and 10(-4) m, of the antagonist, the agonist dose-response curve was shifted to the right with a decrease in the maximum effect." | 1.33 | Antagonism by imidazoline-type drugs of muscarinic and other receptors in the guinea-pig ileum. ( Miller, DD; Patil, PN; Salazar-Bookaman, MM, 2006) |
| "Dextromethorphan (DXM) is a cough-suppressing ingredient in a variety of over-the-counter cough and cold medications." | 1.33 | Effects of dextromethorphan on in vitro contractile responses of mouse and rat urinary bladders. ( Levin, RM; Millington, WR; Sourial, MW; Tadrous, M; Whitbeck, C, 2006) |
| "Partial bladder outlet obstruction (PBOO) is believed to change the functions of the detrusor, and can lead to an overactive detrusor (OD)." | 1.33 | Effect of partial bladder outlet obstruction on detrusor compliance, excitability and contractility in rats. ( Hao, P; Li, L; Qiu, G; Song, B, 2006) |
| "Propiverine is a commonly used antimuscarinic drug used as therapy for symptoms of an overactive bladder." | 1.33 | Propiverine and metabolites: differences in binding to muscarinic receptors and in functional models of detrusor contraction. ( Braeter, M; Hakenberg, OW; Kelly, LU; Ravens, U; Waelbroeck, M; Weiss, A; Wuest, M, 2006) |
| "Thiamine was given 50 mg/kg/day." | 1.33 | Protective effect of high-dose thiamine (B1) on rat detrusor contractility in streptozotocin-induced diabetes mellitus. ( Aydin, Y; Erkul, A; Ozçifçi, M; Turgut, M; Uzuner, K; Yenilmez, A, 2006) |
| "In dose-response curves to alpha stimulation, BBI mediated a shift to the right (decreased receptor sensitivity in bladder/urethra as well as corpora with no change in the maximal response)." | 1.32 | Effect of the Bowman-Birk inhibitor (a soy protein) on in vitro bladder neck/urethral and penile corporal smooth muscle activity. ( Broderick, GA; Kennedy, AR; Levin, RM; Liu, SP; Malkowicz, SB; Wein, AJ, 2003) |
| "To determine whether chronic renal failure (CRF) reduces nitrergic relaxant responses in a rabbit model." | 1.32 | The evaluation of the effects of renal failure on erectile dysfunction in a rabbit model of chronic renal failure. ( Ayan, S; Bagcivan, I; Gokce, G; Kilicarslan, H; Sarac, B; Sarioglu, Y; Yildirim, S, 2003) |
| "Atropine did not inhibit the lobeline-induced responses but abolished the muscarinic responses." | 1.32 | Agonist- and nerve-induced phasic activity in the isolated whole bladder of the guinea pig: evidence for two types of bladder activity. ( Drake, MJ; Gillespie, JI; Harvey, IJ, 2003) |
| "Pilocarpine effect was more often accompanied by membrane depolarization, as was usually seen using carbachol." | 1.32 | Receptor signaling mechanisms underlying muscarinic agonist-evoked contraction in guinea-pig ileal longitudinal smooth muscle. ( Irie, Y; Kato, Y; Komori, S; Kwon, SC; Matsuyama, H; Okamoto, H; Unno, T, 2003) |
| "In nicardipine pretreated condition, the concentration-response curves for the negative inotropic effect of potassium channel blockers were shifted to the right by the increasing concentration of carbachol from 0." | 1.32 | Inhibitory effects of potassium channel blockers on carbachol-induced contraction in rat detrusor muscle. ( Ahn, SC; Oh, SJ, 2003) |
| "Pretreatment with darifenacin (10(-9)-10(-6) mol/l), propiverine (10(-8)- 10(-5) mol/l), oxybutynin (10(-8)-10(-5) mol/l) and atropine (10(-9)-10(-6) mol/l) significantly inhibited maximum EFS-induced contractions." | 1.32 | Pharmacological effects of darifenacin on human isolated urinary bladder. ( Iwashita, H; Masunaga, K; Miyamae, K; Murakami, S; Ohtani, M; Ueda, S; Yoshida, M, 2003) |
| "Melatonin treatment of the CLP group restored these responses." | 1.32 | Melatonin treatment protects against sepsis-induced functional and biochemical changes in rat ileum and urinary bladder. ( Ayanoğlu-Dülger, G; Kapucu, C; Paskaloğlu, K; Sener, G, 2004) |
| "Allergic rhinitis, also known as hay fever, rose fever or summer catarrh, is a major challenge to health professionals." | 1.32 | Mast cell stabilization, lipoxygenase inhibition, hyaluronidase inhibition, antihistaminic and antispasmodic activities of Aller-7, a novel botanical formulation for allergic rhinitis. ( Amit, A; Bagchi, D; Bagchi, M; D'Souza, P; Pratibha, N; Saxena, VS; Stohs, SJ, 2003) |
| "Hydrogen sulfide (H(2)S) is an endogenous vasodilator in mammals, but its presence and function in other vertebrates is unknown." | 1.32 | Hydrogen sulfide as an endogenous regulator of vascular smooth muscle tone in trout. ( Dombkowski, RA; Olson, KR; Russell, MJ, 2004) |
| "An association between hydrocephalus and gastroesophageal motor abnormalities that cause gastroesophageal reflux (GER) is well known." | 1.32 | Foregut smooth muscle reactivity changes in the hydrocephalus-induced infantile rats. ( Ceylan, S; Etus, V; Muezzinoglu, B; Tugay, M; Utkan, T, 2004) |
| "Carbachol was equally effective in generating Ca transients in freshly isolated and cultured cells." | 1.32 | Characterization of the control of intracellular [Ca2+] and the contractile phenotype of cultured human detrusor smooth muscle cells. ( Brown, RA; Fry, CH; Wood, DN, 2004) |
| "Colitis was induced by intracolonic instillation of 4% acetic acid." | 1.32 | Electroacupuncture ameliorates experimental colitis induced by acetic acid in rat. ( Kang, JW; Kim, HJ; Kim, JY; Kim, TW; Kwon, YB; La, JH; Sung, TS; Yang, IS, 2004) |
| "Partial bladder neck obstruction was created surgically by ligating the urethra around a 3F feeding tube." | 1.31 | The early effects of partial outflow obstruction on contractile properties of diabetic and non-diabetic rat bladder. ( Aki, FT; Cetinkaya, M; Gür, S; Oztekin, V; Oztürk, B; Ugurlu, O, 2002) |
| "After 2 weeks of bladder outlet obstruction the upper dome expanded to a significantly higher degree than the lower bladder body." | 1.31 | Regional differences in bladder enlargement and in vitro contractility after outlet obstruction in the rabbit. ( Capello, SA; Longhurst, PA; Schroder, A; Uvelius, B, 2002) |
| "1% amlexanox solution was instilled 5 minutes before every instillation of carbachol ointment." | 1.31 | [Changes in isolated ciliary muscle caused by repeated instillation of carbachol ointment in rabbits and effect of topically applied amlexanox]. ( Gomi, Y; Isaka, M; Ogawa, T; Ushijima, HT; Watanabe, N; Yorozuya, T, 2000) |
| " The presence of 10(-5) M ICI 118, 551, beta(2)-adrenoceptor antagonist, shifted significantly the clenbuterol dose-response to 1 Hz electrical field stimulation (EC(50) 3." | 1.31 | Inhibition of the contractile response of the rat detrusor muscle by the beta(2)-adrenoceptor agonist clenbuterol. ( Elliott, RA; Hudman, D; Norman, RI, 2000) |
| "Following prolonged partial bladder outlet obstruction (BOO) in the mouse, cholinergic mediated detrusor contractility decreases." | 1.31 | Altered response to partial bladder outlet obstruction in mice lacking inducible nitric oxide synthase. ( Connell, JD; Lemack, GE; Lin, VK; Vazquez, D; Zimmern, PE, 2000) |
| "Patients with ulcerative colitis have abnormal rectal motility." | 1.31 | Abnormal contractile properties of rectal smooth muscle in chronic ulcerative colitis. ( Brading, AF; Cook, TA; Mortensen, NJ, 2000) |
| "Prucalopride did not cause relevant inhibition of 5-HT(2A), 5-HT(2B), or 5-HT(3), motilin or cholecystokinin (CCK(1)) receptor-mediated contractions, nor nicotinic or muscarinic acetylcholine receptor-mediated contractions, up to 10 microM." | 1.31 | The in vitro pharmacological profile of prucalopride, a novel enterokinetic compound. ( Bosmans, JP; Briejer, MR; Heylen, L; Jurzak, M; Leysen, JE; Prins, NH; Schuurkes, JA; Van Daele, P, 2001) |
| "Intraocular pressure was measured by pneumatonography (n = 12, 24 eyes)." | 1.31 | Reduction of intraocular pressure by topical administration of an inhibitor of the Rho-associated protein kinase. ( Azuma, M; Oka, T; Waki, M; Yoshida, Y, 2001) |
| "Colitis was induced in rats by intrarectal administration of trinitrobenzenesulfonic acid in ethanol." | 1.31 | Colitis-induced alterations in adrenergic control of circular smooth muscle in vitro in rats. ( Bossone, C; Piñeiro-Carrero, V; Shea-Donohue, T; Zhao, A, 2001) |
| "Doxazosin (dox) is a clinically effective alpha-adrenergic antagonist used in the treatment of symptomatic benign prostatic hyperplasia (BPH)." | 1.31 | Effect of doxazosin on rat urinary bladder function after partial outlet obstruction. ( Das, AK; Eagen, G; Leggett, RE; Levin, RM; Whitbeck, C, 2002) |
| "Erythromycin was found to stimulate motor activity in the upper gastrointestinal tract." | 1.31 | Direct inhibitory effect of erythromycin on human alimentary tract smooth muscle. ( Freund, HR; Hanani, M; Nissan, A, 2002) |
| "Tacrolimus did not activate the neural motilin receptor of the rabbit gastric antrum and had low affinity for the smooth-muscle motilin receptor." | 1.31 | In vitro evaluation of motilin agonism by macrolide immunosuppressive drugs. ( De Vos, M; Depoortere, I; Lefebvre, R; Peeters, TL; Schoonjans, R; Van Vlem, B; Vanholder, R, 2002) |
| "Bronchi from eight cases of sudden infant death syndrome (SIDS) were also studied." | 1.30 | Effect of transmural pressure on preloads and collapse of immature bronchi. ( McFawn, PK; Mitchell, HW, 1997) |
| "To study the effects of anoxia and substrate depletion, both separately and combined, on the contractile responses of guinea-pig detrusor smooth muscle strips to activation of intrinsic nerves, application of agonists and depolarization with high potassium solution." | 1.30 | The effect of anoxia and glucose-free solutions on the contractile response of guinea-pig detrusor strips to intrinsic nerve stimulation and the application of excitatory agonists. ( Brading, AF; McMurray, G; Pessina, F; Wiggin, A, 1997) |
| " Schild plot analysis of cumulative carbachol dose-response curves in the presence of antagonists was consistent with M3-mediated bladder contractions." | 1.30 | Prejunctional M1 facilitory and M2 inhibitory muscarinic receptors mediate rat bladder contractility. ( Braverman, AS; Kohn, IJ; Luthin, GR; Ruggieri, MR, 1998) |
| " However, the inhibition of the combined CPA and CCh response was reduced and the dose-response curve of SIN-1 shifted to the right." | 1.30 | Involvement of intracellular Ca2+ stores in inhibitory effects of NO donor SIN-1 and cGMP. ( Allescher, HD; Franck, H; Puschmann, A; Schusdziarra, V; Storr, M, 1998) |
| "Isradipine appears to be an effective relaxant in rat myometrium." | 1.30 | Inhibitory effects of isradipine on spontaneous and oxytocin- and carbachol-stimulated contractions of rat myometrium. ( Cetin, A; Cetin, M; Kaya, T; Sarioglu, Y, 1998) |
| "(3) Tetrodotoxin (TTX) was tested on the anti-ChE drugs-induced responses." | 1.30 | Contractile and phosphatidylinositol responses of rat trachea to anticholinesterase drugs. ( Hara, T; Iwanaga, S; Makita, T; Shibata, O; Shibata, S; Sumikawa, K; Tsuda, A, 1998) |
| "The carbachol-induced SuTC was assessed in the presence of various Ca2+-channel blockers and drugs affecting intracellular Ca2+ concentration." | 1.30 | Carbachol-induced sustained tonic contraction of rat detrusor muscle. ( Ahn, SC; Choi, H; Kim, KM; Kim, KW; Kim, SJ; Lee, A; Oh, SJ, 1999) |
| " The dose-response curve for CCK-8 alone to induce gallbladder contraction was not significantly different from those caused by CCK-8 plus 1 mumol/L tetrodotoxin or 1 mumol/L atropine." | 1.29 | Characterization of cholecystokinin receptors on the human gallbladder. ( Coleman, R; Concepcion, W; Cox, KL; Esquivel, CO; Nakazato, P; Tokunaga, Y, 1993) |
| " Oxotremorine generated dose-response curves that were similar in both the circular and longitudinal vectors and intermediate to those previously reported for carbachol and aceclidine." | 1.29 | The effect of muscarinic agonists and selective receptor subtype antagonists on the contractile response of the isolated rhesus monkey ciliary muscle. ( Gabelt, BT; Kaufman, PL; Poyer, JF, 1994) |
| "2." | 1.29 | Pharmacological characteristics of liriodenine, isolated from Fissistigma glaucescens, a novel muscarinic receptor antagonist in guinea-pigs. ( Chang, GJ; Ko, FN; Lin, CH; Su, MJ; Teng, CM; Wu, YC, 1994) |
| "Pretreatment with ponalrestat (25 mg kg-1, daily) prevented both the enhanced maximum contractile responses to phenylephrine and the depressed endothelium-dependent relaxations to carbachol in aortae from 14-day diabetic rats." | 1.29 | The effects of aldose reductase inhibition with ponalrestat on changes in vascular function in streptozotocin diabetic rats. ( Chess-Williams, R; Otter, DJ, 1994) |
| " Tissues were precontracted with carbachol or KCl, and relaxation dose-response curves to nifedipine, Mn2+, or Cd2+ were obtained." | 1.29 | Expression of dihydropyridine resistance differs in porcine bronchial and tracheal smooth muscle. ( Croxton, TL; Fleming, C; Hirshman, CA, 1994) |
| "Dantrolene failed to inhibit the caffeine- and CCh-induced contractions depending on intracellularly stored Ca." | 1.29 | Inhibitory effects of dantrolene on contractile responses in gastric smooth muscle of the rat. ( Ito, S; Nakazato, Y; Ohta, T; Satoh, K, 1994) |
| "Atropine pretreatment completely prevented a supramaximal dose of carbachol from inducing ciliary muscle contraction in either vector." | 1.29 | Age does not affect contractile responses of the isolated rhesus monkey ciliary muscle to muscarinic agonists. ( Flügel, C; Kaufman, PL; Poyer, JF, 1993) |
| "In order to evaluate the anticholinergic effect of fentanyl and pethidine, the influence of these drugs on the cumulative dose-response curves of carbacholine on the guinea-pig ileum has been investigated." | 1.29 | Fentanyl and pethidine are antagonists on muscarinic receptors in guinea-pig ileum. ( Hustveit, O; Setekleiv, J, 1993) |
| " Significant dose-response curves were obtained for both carbamylcholine and atropine." | 1.29 | [Isolated smooth muscle cells of the human colon. Cytophysiological study]. ( Balas, D; Giannarelli, S; Rampal, P, 1993) |
| " The contractile response to carbachol was analyzed using dose-response curves." | 1.29 | Novel regulation of muscarinic receptors and their coupling with G proteins in smooth muscle: transient resensitization during desensitizing process. ( Hishinuma, S; Kurokawa, M; Matsumoto, Y; Uchida, MK, 1993) |
| "With carbachol, there was a 20-fold increase in the [3H]-MI incorporation rate into inositol phospholipids, decreases in PI and PIP2 contents, and increases in phosphatidic acid and diacylglycerol contents." | 1.29 | Common phosphatidylinositol 4,5-bisphosphate pools are involved in carbachol and serotonin activation of tracheal smooth muscle. ( Baron, CB; Blackman, D; Coburn, RF; Pompeo, J, 1993) |
| " However, tracheas treated with U-73122 for 10 min prior to the addition of antigen, demonstrated a 3 log rightward shift in the OA dose-response curve with an IC50 of 7 microM." | 1.29 | Effect of phospholipase C inhibitor U-73122 on antigen-induced airway smooth muscle contraction in guinea pigs. ( Bramley, A; Chan, H; Chan-Yeung, M; Howard, S; Langlands, J; Salari, H; Schellenberg, R, 1993) |
| "Devazepide displayed lower affinity against pentagastrin than against CCK-8S." | 1.29 | Characterization of CCK receptors in a novel smooth muscle preparation from the guinea-pig stomach by use of the selective antagonists CI-988, L-365,260 and devazepide. ( Boyle, SJ; McKnight, AT; Tang, KW; Woodruff, GN, 1993) |
| "Histamine responses were blocked by the H1 antagonist mepyramine but were not altered by a diamine oxidase inhibitor." | 1.29 | Altered small intestinal smooth muscle function in Crohn's disease. ( Collins, SM; Huizinga, JD; Riddell, RH; Vermillion, DL, 1993) |
| "When carbachol was added to the chamber, the electrode responded when the solution was bubbled with 20% but not with 40% or 95% of oxygen, suggesting a much faster decomposition of nitric oxide in the presence of higher concentrations of oxygen." | 1.29 | A nitric oxide-sensitive electrode: requirement of lower oxygen concentration for detecting nitric oxide from the tissue. ( Fukushima, S; Hashimoto, M; Ishida, Y; Isokawa, S; Masumura, S; Momose, K; Murakami, E; Nakayama, K; Sasaki, T; Tamura, K, 1996) |
| " Dose-response curves to cholecystokinin-octapeptide and carbachol were obtained." | 1.29 | Gallbladder motility in vitro in men with gallstones following Billroth II gastric resection. ( Caruso, ML; Lorusso, D; Maselli, MA; Pezzolla, F; Piepoli, AL, 1996) |
| " The changes in the contractile responses of the strips to carbachol administered cumulatively were studied, and the EC50 and pD2 values were calculated from the dose-response curves." | 1.29 | [The reactivity of canine colonic and ileal smooth muscle to carbachol (Jestryl)]. ( Atanasova, E; Noeva, A; Todorov, S, 1994) |
| ") did not bronchodilate but caused a parallel 7 fold rightward shift in the histamine dose-response curve." | 1.29 | Inhibition of bronchospasm and ozone-induced airway hyperresponsiveness in the guinea-pig by CDP840, a novel phosphodiesterase type 4 inhibitor. ( Gozzard, N; Higgs, G; Holbrook, M; Hughes, B; James, T, 1996) |
| "3." | 1.29 | Major difference between rat and guinea-pig ureter in the ability of agonists and caffeine to release Ca2+ and influence force. ( Burdyga, TV; Taggart, MJ; Wray, S, 1995) |
| " Dose-response curves to carbachol and isoproterenol were constructed using isolated strips of tracheal smooth muscle, with or without epithelium." | 1.29 | A morphometric and functional study of the toxicity of atmospheric ammonia in the extrathoracic airways in pigs. ( Ansay, M; Beerens, D; Charlier, G; Coignoul, F; Foliguet, B; Grignon, G; Gustin, P; Lambotte, JL; Prouvost, JF; Urbain, B; Vidic, B, 1996) |
| "The carbachol-induced increase in the Ca2+ sensitivity of force production in beta-escin-permeabilized intestinal smooth muscle was enhanced in preparations that were loaded with the constitutively active mutant of RhoA, Val14RhoA, and was inhibited by exoenzyme C3 from Clostridium botulinum, which ADP-ribosylates and inactivates small GTPases of the Rho family." | 1.29 | Role of Rho proteins in carbachol-induced contractions in intact and permeabilized guinea-pig intestinal smooth muscle. ( Aktories, K; Just, I; Otto, B; Pfitzer, G; Steusloff, A, 1996) |
| "Carbachol failed to produce the characteristic phasic and tonic components of smooth muscle contractions." | 1.28 | Receptor-operated calcium-channels in isolated rabbit jejunum. ( Bhattacharya, SK; Ramarao, P; Sen, AP, 1992) |
| "When tiropramide was added during the sustained phase of the K+ (60 mM)-contracture, IC50 values of tiropramide for the contraction and the increased fluorescence were 1." | 1.28 | Possible mechanisms of action of the antispasmodic agent tiropramide in the isolated detrusor from rats. ( Kubota, K; Matsuoka, Y; Nagahamaya, K; Shirane, M; Sunagane, N; Tsunematsu, R; Uruno, T; Wada, K, 1992) |
| " Compound MV 8612 (8 and 16 microM) and MV 8610 (12 and 24 microM) caused a graded rightward displacement of BK dose-response curves in the isolated guinea pig trachea (dose ratio 2- to 4-fold)." | 1.28 | Effect of compounds from Mandevilla velutina on bradykinin-mediated contractile and relaxant responses of the isolated guinea pig trachea. ( Calixto, JB; Cruz, AB; Medeiros, YS; Yunes, RA, 1992) |
| " The dose-response curves to these agonists showed a 44% reduction in maximum contractile response for ACh (P < 0." | 1.28 | The effect of in vivo oestrogen pretreatment on the contractile response of rat isolated detrusor muscle. ( Castleden, CM; Elliott, RA; Miodrag, A, 1992) |
| "Isoproterenol treatment inhibited agonist-induced contraction by decreasing [Ca2+]i and thereby light chain phosphorylation." | 1.28 | Regulation of the Ca2+ dependence of smooth muscle contraction. ( Kamm, KE; Kubota, Y; Stull, JT; Tang, DC, 1992) |
| "2." | 1.28 | Dicentrine, a natural vascular alpha 1-adrenoceptor antagonist, isolated from Lindera megaphylla. ( Chen, CC; Huang, TF; Huang, YL; Ko, FN; Teng, CM; Yu, SM, 1991) |
| " Insulin had no significant influence on the carbachol contractile dose-response curve nor did it affect the cholinergically mediated 'on-contraction' at onset of the electrical stimulus." | 1.28 | Modulatory effect of insulin on rat small intestinal motility and peptide release in vitro. ( Allescher, HD; Classen, M; Schusdziarra, V; Willis, S, 1991) |
| "125I-pindolol binding was inhibited by the three agonists, with relative potencies (IC50S) of ISO (0." | 1.28 | Characterization of beta-adrenoreceptors on smooth muscle cells from guinea pig stomach. ( Jensen, RT; Maton, PN; Zhang, L, 1990) |
| "Carbachol was applied at 20 degrees C for 5 min." | 1.28 | Carbachol-induced nonspecific desensitization in guinea-pig ileum. ( Casteels, R; Droogmans, G; Himpens, B, 1991) |
| " On the other hand, the dose-response relationship to carbachol, a cholinergic agonist resistant to cholinesterase degradation, was unaffected by CTZ." | 1.28 | The effect of chlorothiazide on neurally mediated contraction of rabbit bronchial smooth muscle. ( Brunner, SL; Scott, JY; Tanaka, DT, 1992) |
| "Patients with neurogenic bladder underwent augmentation enterocystoplasty because of low bladder compliance or uninhibited contraction which resulted in urinary incontinence and/or vesicoureteral reflux." | 1.28 | [Pharmacologic characteristics of human neurogenic bladder: response to KCl, carbachol, ATP and CaCl2]. ( Kato, T; Kondo, A; Miyake, K; Saito, M, 1991) |
| "The role of calcium in drug-induced contractions of rat gastric fundus strips was evaluated by determining the effect of two procedures on the dose-response curves of agonists: a) removal of calcium from the nutrient solution and b) blockade of calcium channels with the dihydropyridine isradipine." | 1.28 | Comparison of the effect of calcium withdrawal from the medium and of blockade of extracellular calcium entry by isradipine on the contractile responses of the isolated rat stomach. ( Garcia, AG; Jurkiewicz, A; Jurkiewicz, NH; Smaili, SS, 1991) |
| "Carbachol was used for activation of the contractile apparatus." | 1.28 | Mechanical properties of isolated smooth muscle from rabbit sphincter of Oddi and duodenum. ( Elbrønd, H; Forman, A; Tøttrup, A, 1991) |
| "Quinpirole did not enhance contractile responses to acetylcholine and carbachol, but in high concentrations induced contractions in unstimulated preparations." | 1.28 | Influence of the DA2-receptor agonist quinpirole on the guinea pig ileum. ( Guenaneche, F; Lefebvre, RA, 1990) |
| "These data demonstrate that hemorrhagic shock and reperfusion affect digestive motility." | 1.28 | Biliary and gut function following shock. ( Calabuig, R; Harari, Y; Li, YF; Moody, FG; Rodriguez, LF; Weisbrodt, NW, 1990) |
| "Carbachol (10(-6) M) was used for submaximal activation of the contractile apparatus." | 1.28 | Mechanical properties of isolated human esophageal smooth muscle. ( Andersson, KE; Forman, A; Funch-Jensen, P; Tøttrup, A; Uldbjerg, N, 1990) |
| "Carbachol response was reversibly inhibited when [Mg]i decreased to less than 1/10 of the control." | 1.28 | Intracellular free magnesium concentration in the taenia isolated from guinea-pig caecum. ( Nakayama, S; Tomita, T, 1990) |
| " Carbachol dose-response relations and maximal contraction amplitude to carbachol was similar at pH 7." | 1.28 | Effects of variations in extracellular pH on spontaneous contractile activity and response to nerve stimulation in smooth muscle from rat urinary bladder. ( Andersson, PO; Malmgren, A; Uvelius, B, 1990) |
| "Papaverine is a non-specific smooth muscle relaxant and is thought to act at a site beyond the receptor sites on the cell membrane." | 1.28 | Effects of papaverine on human isolated bladder muscle. ( Hertle, L; Nawrath, H, 1990) |
| "Himbacine was the most potent compound and the 15-fold selectivity exhibited for the M2 muscarinic receptor was greater than that found with any of the other compounds examined." | 1.28 | Structure-activity relationships of some Galbulimima alkaloids related to himbacine. ( Choo, LK; Darroch, SA; Mitchelson, F; Taylor, WC, 1990) |
| "Eledoisin failed to cause tachyphylaxis under the conditions of these experiments." | 1.28 | Classification of tachykinin receptors in muscularis mucosae of opossum oesophagus. ( Bowker, P; Cipris, S; Daniel, EE; Manaka, Y; Regoli, D, 1989) |
| "Treatment with carbachol, isoproterenol, or phorbol 12,13-dibutyrate resulted in no significant change." | 1.28 | Phosphorylation of smooth muscle myosin heavy and light chains. Effects of phorbol dibutyrate and agonists. ( Hsu, LC; Kamm, KE; Kubota, Y; Stull, JT, 1989) |
| "Pretreatment with carbachol in Cl-ion-containing or Cl-ion-free Krebs solution or with 10(-3) M 9-aminoacridine abolished or markedly reduced relaxation due to VIP applied exogenously but not that elicited by field stimulation of non-adrenergic, non-cholinergic nerves." | 1.28 | Vasoactive intestinal polypeptide and non-adrenergic, non-cholinergic inhibition in lower oesophageal sphincter of opossum. ( Daniel, EE; Jager, LP; Jury, J, 1989) |
| " Data was analyzed by comparing mean maximal tension, dose-response curves, and EC50 values for tissue from the two groups of animals." | 1.28 | Cholinergic responsiveness of intestinal muscle in the pregnant guinea pig. ( DeFlora, E; Scott, LD, 1989) |
| " Dose-response studies were performed with increasing concentrations of histamine both in the absence and presence of H1 receptor blockade using 10(-5) M diphenhydramine." | 1.27 | Temporal relationship of cyclic nucleotide levels and calcium exchange to histamine-induced tension development. ( Kolbeck, RC; Speir, WA, 1984) |
| "Potassium chloride Tmax was potentiated in the second CCRC at 37 degrees C but not at 20 degrees C." | 1.27 | The effect of alteration in temperature on contractile responses in human airways in vitro. ( Armour, CL; Black, JL; Shaw, J, 1984) |
| " Phenoxybenzamine did not affect the dose-response curves to SP, eledoisin-related peptide (ERP), kassinin, eledoisin or physalaemin, nor did it affect the responses to individual doses of DPDPDT or DT79." | 1.27 | A study of [D-Pro2, D-Phe7, D-Trp9]-substance P and [D-Trp7,9]-substance P as tachykinin partial agonists in the rat colon. ( Bailey, SJ; Jordan, CC, 1984) |
| "(+)-pindolol was about 200 times less potent in this respect." | 1.27 | Steric aspects of agonism and antagonism at beta-adrenoceptors: experiments with the enantiomers of terbutaline and pindolol. ( Jeppsson, AB; Johansson, U; Waldeck, B, 1984) |
| " Incubation of the isolated guinea pig ileum for 30 min with BM 123 at 20 microM and 2 microM caused 94% and 48% receptor alkylation, respectively, as calculated from the shift in the agonist dose-response curve." | 1.27 | The conversion of 2-chloroalkylamine analogues of oxotremorine to aziridinium ions and their interactions with muscarinic receptors in the guinea pig ileum. ( Dahlbom, R; Ehlert, FJ; Jenden, DJ; Resul, B; Ringdahl, B, 1984) |
| "Clonidine was the most potent agonist against peristaltic reflex and the weakest agonist in relaxing circular muscle." | 1.27 | Changes in sensitivity to the inhibitory effects of adrenergic agonists on intestinal motor activity after chronic sympathetic denervation. ( Crema, A; D'Angelo, L; Frigo, GM; Lecchini, S; Marcoli, M; Tonini, M, 1984) |
| " Crude extracts of Sesbania drummondii were prepared and 2 dosage levels, 0." | 1.27 | Assessment of smooth muscle function in Sesbania drummondii toxicosis in Gallus domesticus. ( Flory, W; Hebert, CD; Strain, GM; Tucker, TA; Venugopalan, CS, 1984) |
| "Dose-response studies in vitro and in vivo revealed four types of alterations of dose-response curves along with changes in the baseline, two of them in accordance and two in disagreement with Wilder's law of initial value (LIV)." | 1.27 | The underlying bases of pharmacological results in agreement or disagreement with the law of initial value. ( Brunner, F; Pöch, G, 1984) |
| " Cumulative dose-response curves point to a non-competitive antagonism." | 1.27 | Spasmolytic activity of the flavonoids from Thymus vulgaris. ( Lemli, JA; Van Den Broucke, CO, 1983) |
| "A substance P antagonist was ineffective in blocking responses to field stimulation or to exogenous substance P." | 1.27 | The role of substance P in the human urinary bladder. ( Daniel, EE; Kalbfleisch, RE, 1987) |
| " Ketamine, 3 X 10(-4) M, produced a shift to the right of the dose-response curve without altering the maximum contractile responses to carbachol, but had no effect on dose-response curves to substance P, the putative noncholinergic transmitter in these bronchial segments." | 1.27 | Differential effect of ketamine on cholinergic- and noncholinergic-induced contractions of isolated guinea-pig bronchi. ( Brunson, DB; Buckner, CK; Laravuso, RB; Leblanc, PH; Will, JA, 1987) |
| "Atropine was 70-100 times more potent than pirenzepine and 8-25 times more potent than hexahydrosiladifenidol." | 1.27 | Muscarinic receptors on nerves and muscles in opossum esophagus muscularis mucosa. ( Bowker, P; Daniel, EE; Jury, J, 1987) |
| "If carbachol was added to cells after varying times in the EGTA-containing solution, the ability to initiate a contraction declined exponentially with a half-time of 160 s." | 1.27 | Calcium and contractions of isolated smooth muscle cells from rat myometrium. ( Berezin, I; Collins, SM; Crankshaw, J; Daniel, EE; Kyozuka, M, 1987) |
| " Decreasing [Mg2+]0 from the optimal concentration of 1 to 0 mM caused a 20-fold parallel rightward displacement of the oxytocin dose-response curve." | 1.27 | Magnesium ions and oxytocin sensitivity of the male mouse anococcygeus. ( Gibson, A, 1985) |
| "Pretreatment with reserpine increased the potency of salbutamol at each concentration of carbachol." | 1.27 | The effect of varying carbachol concentration on the slope of Schild plots of selective beta-adrenoceptor antagonists in the carbachol-contracted guinea-pig trachea. ( Donahue, JY; Keith, RA; Salama, AI, 1986) |
| "(+)-Clenbuterol was at least 1,000 times less potent in this respect." | 1.27 | Steric aspects of agonism and antagonism at beta-adrenoceptors: experiments with the enantiomers of clenbuterol. ( Waldeck, B; Widmark, E, 1985) |
| "Nisoxetine was also less potent than desipramine in inhibiting responses to histamine, carbachol and bradykinin on the guinea-pig isolated ileum." | 1.27 | Some pharmacological actions of nisoxetine, a bicyclic inhibitor of noradrenaline uptake. ( Foley, AJ; Leedham, JA; Pennefather, JN, 1985) |
| "Thymol, which has been reported to be one of the most potent stimulators of the Ca-induced Ca release in the sarcoplasmic reticulum of skeletal muscle, enhanced the 45Ca-efflux from the taenia microsomes in the presence of ATP dose-dependently, and its mode of action seemed bimodal." | 1.27 | Some properties and mechanisms of thymol-induced release of calcium from the calcium-store in guinea-pig taenia caecum. ( Hisayama, T; Takayanagi, I, 1986) |
| " Isoproterenol, a known relaxant of these cells, caused a small decrease in Cai2+ (approximately 40 nM) below rest, when applied in maximal dosage (10(-4) M)." | 1.27 | Calcium transients and resting levels in isolated smooth muscle cells as monitored with quin 2. ( Fay, FS; Williams, DA, 1986) |
| "Prazosin was 300 times more active than rauwolscine in inhibiting NA-induced contractions." | 1.27 | Comparison of the responses to drugs acting on adrenoreceptors and muscarinic receptors in human isolated corpus cavernosum and cavernous artery. ( Andersson, KE; Hedlund, H, 1985) |
| " Atropine or tetrodotoxin significantly reduced CCK-8-evoked initial phasic contraction and produced a rightward shift of the dose-response curve for CCK-8 (10(-10)-3 x 10(-7) M)." | 1.27 | Effects of cholecystokinin octapeptide on contractile motility of guinea pig common bile duct. ( Kantoh, M; Kusunoki, M; Takahashi, T; Utsunomiya, J; Yamamura, T, 1988) |
| " In contrast, a combination of methoctramine with gallamine produced a less than additive shift of the dose-response curve for carbachol, confirming that gallamine acts as an allosteric antagonist at cardiac muscarinic receptors." | 1.27 | Antimuscarinic action of methoctramine, a new cardioselective M-2 muscarinic receptor antagonist, alone and in combination with atropine and gallamine. ( Angeli, P; Lambrecht, G; Melchiorre, C; Mutschler, E; Picchio, MT; Wess, J, 1987) |
| "Himbacine was a competitive antagonist of carbachol in both preparations." | 1.27 | Interaction of himbacine with carbachol at muscarinic receptors of heart and smooth muscle. ( Cobbin, LB; Gilani, SA, 1987) |
| "Atropine was about 2 orders of magnitude more potent than PZ in inhibiting the CCh-induced biochemical and pharmacological responses and [3H] QNB binding, indicating the preponderance of M2 receptors in this smooth muscle." | 1.27 | M2 muscarinic receptor subtype is associated with inositol trisphosphate accumulation, myosin light chain phosphorylation and contraction in sphincter smooth muscle of rabbit iris. ( Abdel-Latif, AA; Akhtar, RA; Honkanen, RE; Howe, PH, 1987) |
| "Theophylline was significantly less effective in antagonizing the bronchospasm elicited by maximally effective dose (100 micrograms/kg i." | 1.27 | Blockade by theophylline of capsaicin-induced motor effects in guinea-pig airways. ( Agostini, R; Ballati, L; Conti, S; Manzini, S, 1987) |
| "Isoarecolone methiodide has been reported previously to be a potent agonist at peripheral nicotinic-cholinergic receptors." | 1.27 | Isoarecolone can inhibit nicotine binding and produce nicotine-like discriminative stimulus effects in rats. ( Reavill, C; Spivak, CE; Stolerman, IP; Waters, JA, 1987) |
| " Human bronchi were obtained from thoracotomy and dose-response relationships for each agonist were obtained for bronchial rings suspended in isotonic Krebs-Henseleit solution (290 mOsm)." | 1.27 | The effect of non-isotonic solutions on human isolated airway smooth muscle. ( Anderson, SD; Black, JL; Finney, MJ, 1987) |
| "Carbachol-treated tracheal ring dimensions were compared with those of their matched theophylline-treated rings." | 1.27 | Quantitative measurement of smooth muscle shortening in isolated pig trachea. ( Hogg, JC; James, AL; Moreno, RH; Paré, PD, 1987) |
| " Mechanical responses of sensitized TSM were characterized by hyperreactivity (upward shift of the dose-response relationship) to acetylcholine (ACh), atropine-sensitive spontaneous base line activity and prolonged isometric force plateaus." | 1.27 | Local parasympathetic mechanisms for ragweed-sensitized canine trachealis hyperresponsiveness. ( Kepron, W; Kroeger, EA; Mitchell, RW; Stephens, NL, 1987) |
| " Joint application of ACh and CCh generated a dose-response profile consistent with a model of competitive antagonism between a full agonist (CCh) and a partial one (ACh)." | 1.27 | A study of the contractile response to acetylcholine in human ileal and detrusor muscle: origin of the low efficacy of acetylcholine. ( Cohen, S; Nissenkorn, I; Rubinstein, R, 1986) |
| "Darodipine is a new light stable dihydropyridine calcium antagonist." | 1.27 | Effect of calcium antagonist darodipine on the isolated human heart. ( Carey, B; Ginsburg, R; Zera, P, 1986) |
| "Both tetrodotoxin treatment and calcium omission from the medium prevented such an evoked-outflow of tritium." | 1.27 | Presynaptic inhibitory muscarinic receptors modulating [3H] acetylcholine release in the rat urinary bladder. ( Chiari, MC; D'Agostino, G; Grana, E; Kilbinger, H, 1986) |
| " Dose-response contraction curves for histamine, carbachol, and norepinephrine were obtained in the ileal, parenchymal, and aortic strips, respectively." | 1.27 | Smooth muscle inhibition by an extract of Sesbania drummondii. ( Flory, W; Marceau-Day, ML; O'Malley, NA; Venugopalan, CS, 1987) |
| " Concurrently the effect of nortriptyline low dosage therapy was studied in 21 women suffering from motor or sensory urgency and urge incontinence." | 1.27 | Selective effect of nortriptyline on smooth muscle as an anticholinergic drug: a pharmacological and clinical study. ( Cohen, S; Katz, A; Nissenkorn, I; Rubinstein, R, 1986) |
| " Carbachol dose-response curves for isometric stress development and myosin phosphorylation were superimposable but shifted to the left of the shortening velocity dose-response." | 1.27 | Calcium dependence of myosin phosphorylation and airway smooth muscle contraction and relaxation. ( Gerthoffer, WT, 1986) |
| "5 mg/l; 20 min), when administered to guinea pigs 1 h before exposure to acetylcholine (Ach), induced potentiation of cumulative dose-response curve of this agonist on isolated tracheal strips as well as a decrease of the lethal doses of Ach." | 1.27 | Kerosene aerosol induces guinea-pig airway hyperreactivity to acetylcholine. ( Arruzazabala, L; Casacó, A; de la Vega, AR; García, M; González, R, 1985) |
| "Muscle contraction was apparent at lower concentrations of carbamylcholine." | 1.27 | Relationship between stimulated inositol lipid hydrolysis and contractility in guinea-pig visceral longitudinal smooth muscle. ( Best, L; Bolton, TB; Brooks, KJ, 1985) |
| "Pilocarpine which is a well-known partial agonist on muscarinic receptors in most smooth muscles did not cause any contraction in this tissue." | 1.27 | Muscarinic acetylcholine receptors in the rabbit ciliary body smooth muscle: spare receptors and threshold phenomenon. ( Konno, F; Takayanagi, I, 1985) |
| "Naloxone treatment of mice did not affect the sensitivity of the isolated vas deferens to noradrenaline, carbachol or potassium chloride." | 1.27 | Effects of chronic drug treatment on the sensitivity of mouse vas deferens to drugs. ( McCulloch, CR; Pollock, D, 1985) |
| " In each airway segment, cumulative dose-response effects of ovalbumin were obtained in the absence and presence of a maximally effective concentration of a beta adrenergic receptor agonist, sulfonterol." | 1.26 | Parainfluenza 3 infection blocks the ability of a beta adrenergic receptor agonist to inhibit antigen-induced contraction of guinea pig isolated airway smooth muscle. ( Ain-Shoka, AA; Buckner, CK; Busse, WW; Clayton, DE; Dick, EC; Shult, P, 1981) |
| "Propranolol (10(-6)M) pretreatment significantly antagonized the relaxant responses of the bronchioles to isoproternol: THC antagonized these responses to a smaller degree." | 1.26 | Delta-9-tetrahydrocannabinol on isolated human bronchioles. ( Forney, RB; Goodman, FR; Orzelek-O'Neil, RM, 1980) |
| " Inhibition by proglumide was competitive and resulted in a parallel rightward shift of the cholecystokinin dose-response curve." | 1.26 | Cholecystokinin-induced contraction of dispersed smooth muscle cells. ( Collins, SM; Gardner, JD, 1982) |
| "Bassianolide (BASS) is a cyclodepsipeptide isolated from cultured mycelia of Beauveria bassiana and is pathogenic to insects." | 1.26 | Inhibitory effect of bassianolide, a cyclodepsipeptide, on drug-induced contractions of isolated smooth muscle preparations. ( Isogai, A; Kamizaki, J; Kato, K; Kometani, A; Nakajyo, S; Shimizu, K; Urakawa, N, 1982) |
| " Acetylcholine dose-response curves were shifted to the right while Ba2+ curves were unaffected." | 1.26 | Influence of N-ethylmaleimide on cholinoceptors and responses in longitudinal muscles from guinea-pig ileum. ( Aronstam, RS; Carrier, GO, 1982) |
| "Atropine was approximately 750 times more potent than terodiline." | 1.26 | Anticholinergic and calcium antagonistic effects of terodiline in rabbit urinary bladder. ( Andersson, KE; Husted, S; Ostergaard, JR; Sommer, L, 1980) |
| " 3 The log dose-response curve for the contractile response of longitudinal muscle strips from guinea-pig intestine to carbachol was shifted in a parallel fashion by low concentrations of tetracaine, but flattened by higher doses." | 1.26 | The interaction of amine local anaesthetics with muscarinic receptors. ( Taylor, WJ; Wolf, A; Young, JM, 1980) |
| " (2) The dose-response curves for the relaxation by ISO shifted to the right in a parallel manner as the concentration of the spasmogen increased, and became stationary at high concentrations of the spasmogen." | 1.26 | Studies on the mode of antagonism between adrenergic beta-mimetics and beta-blocking agents (III). Functional antagonism between beta-mimetics and spasmogens. ( Ohashi, M, 1976) |
| " The results showed that the kinetics were competitive (parallel shift of dose-response curves to the right and a slope of Schild plot of 1." | 1.26 | Kinetic analysis of the AH8165-receptor interaction at the mammalian neuromuscular junction. ( Waud, BE, 1977) |
| " This theory attributes the thousand-fold increase in sensitivity to exogenous acetylcholine produced by anticholinesterases in chick biventer cervicis muscles largely to an alteration in acetylcholine concentration gradient within the muscle and accounts satisfactorily for the shift in the dose-response curve for acetylcholine which occurs after treatment of the muscles with various concentrations of physostigmine." | 1.26 | The relationship between cholinesterase inhibition in the chick biventer cervicis muscle and its sensitivity to exogenous acetylcholine. ( Green, AL; Lord, JA; Marshall, IG, 1978) |
| " Anticholinesterase treatment shifted the dose-response curve for carbachol markedly to the left as far as the contracture attained after 4-6 min incubation was concerned." | 1.26 | An analysis of the mode of action of carbachol on the chick biventer cervicis nerve--muscle preparation. ( Chang, CC; Su, MJ; Tang, SS, 1976) |
| "3 Propranolol caused a parallel shift to the right of the noradrenaline dose-response curve which was not changed by phentolamine." | 1.26 | alpha And beta-adrenoceptors in the detrusor muscle and bladder base of the pig and beta-adrenoceptors in the detrusor muscle of man. ( Larsen, JJ, 1979) |
| " Cumulative dose-response curves were obtained in substrate-rich (5." | 1.26 | Role of glucose in contractility of airway smooth muscle. ( Loader, J; Souhrada, JF, 1979) |
| "Pyrilamine was equally effective in competitively blocking histamine response in both the detrusor and neck preparations." | 1.26 | Comparison of the urinary bladder base and detrusor to cholinergic and histaminergic receptor activation in the rabbit. ( Anderson, GF; Van Buren, GA, 1979) |
| "3." | 1.26 | [Functional studies of the cardia muscles in achalasia]. ( Bruch, HP; Gay, B; Kujath, P; Laven, R; Schmidt, E, 1977) |
| " 2 Log affinity constants were derived from log dose-response curves at dose-ratios less than 100, where parallel curves were obtained." | 1.26 | Structure-activity relationships for the anticholinoceptor action of tricyclic antidepressants. ( Shein, K; Smith, SE, 1978) |
| " Reproduceable responses sufficient for calculating dose-response curves, could be obtained up to 30 h after death." | 1.26 | Physiological and pharmacological studies on isolated human bronchial preparations. ( Berlin, E; Boe, J; Thulesius, O, 1978) |
| "Pretreatment of carbachol (in vitro), in various doses (5." | 1.26 | Carbachol-induced sensitivity changes in skeletal muscle and their mechanism of action. ( Geetha, VS; Kameswaran, L; Nazimudeen, SK; Ramaswamy, S, 1978) |
| "Dicyclomine was only about 1/30 as potent as atropine in competitive antimuscarinic activity." | 1.26 | Antimuscarinic and noncompetitive antagonist properties of dicyclomine hydrochloride in isolated human and rabbit bladder muscle. ( Awad, SA; Downie, JW; Twiddy, DA, 1977) |
| " Both drugs also shift to the left the dose-response curves for noradrenaline and adrenaline on isolated strips, cocaine being most potent." | 1.26 | Uptake and release of catecholamines in sympathetic nerve fibres in the spleen of the cod, Gadus morhua. ( Holmgren, S; Nilsson, S, 1976) |
| " The effect of acetylcholine is also significantly potentiated by pretreatment with 6-hydroxydopamine or denervation, but not by reserpine, while the dose-response curve for carbachol is not affected by the specific cholinesterase inhibitor BW 284 C51, denervation or 6-hydroxydopamine." | 1.26 | Uptake and release of catecholamines in sympathetic nerve fibers in the spleen of the cod, Gadus morhua. ( Holmgren, S; Nilsson, S, 1976) |
| " Drug potency was obtained from log dose-response curves." | 1.26 | Factors determining the potency of mydriatic drugs in man. ( Smith, SA, 1976) |
| " 4 On the frog rectus abdominis the alkylating agent, decamethonium mustard, does not produce any 'parallel shift' of the dose-response curve for carbachol, the only result of alkylation being a decrease in maximal response, which is more pronounced in isometric than in isotonic conditions." | 1.26 | Isotonic and isometric responses of different tonic muscles to agonists and antagonists. ( Michelson, MJ; Shelkovnikov, SA, 1976) |
| " In these studies, it is shown that increasing concentrations of carbamylcholine (carbachol) result in a shift to the right of the dose-response curves to (-)-isoproterenol and (-)-soterenol and a reduction of the maximum degree of relaxation produced by these agonists relative to that produced by papaverine." | 1.25 | On the use of functional antagonism to estimate dissociation constants for beta adrenergic receptor agonists in isolated guinea-pig trachea. ( Buckner, CK; Saini, RK, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 736 (36.22) | 18.7374 |
| 1990's | 575 (28.30) | 18.2507 |
| 2000's | 451 (22.19) | 29.6817 |
| 2010's | 239 (11.76) | 24.3611 |
| 2020's | 31 (1.53) | 2.80 |
| Authors | Studies |
|---|---|
| Rodger, IW | 2 |
| Hersom, AS | 1 |
| Waigh, RD | 1 |
| Valli, MJ | 1 |
| Tang, Y | 1 |
| Kosh, JW | 1 |
| Chapman, JM | 1 |
| Sowell, JW | 1 |
| Nilsson, BM | 2 |
| Vargas, HM | 3 |
| Hacksell, U | 4 |
| Showell, GA | 1 |
| Baker, R | 1 |
| Davis, J | 1 |
| Hargreaves, R | 1 |
| Freedman, SB | 1 |
| Hoogsteen, K | 1 |
| Patel, S | 1 |
| Snow, RJ | 1 |
| Lundkvist, JR | 2 |
| Caldirola, P | 1 |
| Ringdahl, B | 11 |
| Roch, M | 2 |
| Jenden, DJ | 3 |
| Teodori, E | 5 |
| Gualtieri, F | 4 |
| Angeli, P | 5 |
| Brasili, L | 6 |
| Giannella, M | 2 |
| Pigini, M | 1 |
| Scapecchi, S | 1 |
| Matucci, R | 3 |
| Bellucci, C | 2 |
| Buccioni, M | 1 |
| Dei, S | 2 |
| Guandalini, L | 2 |
| Martelli, C | 1 |
| Manetti, D | 2 |
| Martini, E | 1 |
| Marucci, G | 1 |
| Nesi, M | 2 |
| Romanelli, MN | 3 |
| Joo, NS | 2 |
| Cho, HJ | 1 |
| Shinbashi, M | 1 |
| Choi, JY | 1 |
| Milla, CE | 1 |
| Engelhardt, JF | 1 |
| Wine, JJ | 2 |
| Wang, H | 2 |
| Esemu-Ezewu, P | 1 |
| Pan, J | 2 |
| Ivanovska, J | 1 |
| Gauda, EB | 1 |
| Belik, J | 2 |
| Zhang, YL | 1 |
| Zhang, RG | 1 |
| Chen, FY | 1 |
| Qiu, ZE | 1 |
| Chen, L | 1 |
| Huang, ZX | 1 |
| Huang, J | 3 |
| Zhu, YX | 1 |
| Zhao, L | 1 |
| Zhou, WL | 1 |
| Erdogan, BR | 2 |
| Yesilyurt, ZE | 2 |
| Arioglu-Inan, E | 2 |
| Michel, MC | 9 |
| Patejdl, R | 1 |
| Klawitter, F | 1 |
| Walter, U | 1 |
| Zanaty, K | 1 |
| Schwandner, F | 1 |
| Sellmann, T | 2 |
| Porath, K | 2 |
| Ehler, J | 1 |
| Morgan, LM | 1 |
| Martin, SL | 2 |
| Mullins, ND | 1 |
| Hollywood, MA | 3 |
| Thornbury, KD | 3 |
| Sergeant, GP | 3 |
| Huang, R | 1 |
| Tamalunas, A | 1 |
| Waidelich, R | 1 |
| Strittmatter, F | 2 |
| Stief, CG | 4 |
| Hennenberg, M | 3 |
| Lambrinos, G | 1 |
| Cristofaro, V | 2 |
| Pelton, K | 1 |
| Bigger-Allen, A | 1 |
| Doyle, C | 1 |
| Vasquez, E | 1 |
| Bielenberg, DR | 1 |
| Sullivan, MP | 2 |
| Adam, RM | 1 |
| Birulina, YG | 1 |
| Ivanov, VV | 1 |
| Buiko, EE | 1 |
| Dzyuman, AN | 1 |
| Nosarev, AV | 1 |
| Voronkova, OV | 1 |
| Vol'khina, MO | 1 |
| Gusakova, SV | 1 |
| Xu, S | 1 |
| Karmacharya, N | 1 |
| Woo, J | 1 |
| Cao, G | 2 |
| Guo, C | 2 |
| Gow, A | 1 |
| Panettieri, RA | 8 |
| Jude, JA | 1 |
| Ivanova, DV | 2 |
| Ziganhin, AU | 1 |
| Engin, S | 1 |
| Barut, EN | 1 |
| Erac, Y | 1 |
| Sari, S | 1 |
| Kadioglu, M | 1 |
| Dwivedi, R | 1 |
| Drumm, BT | 1 |
| Alkawadri, T | 1 |
| Maher, S | 1 |
| Bayachou, M | 1 |
| Fu, P | 1 |
| Hijaz, A | 1 |
| Liu, G | 2 |
| Ziganshin, AU | 10 |
| Gomes, LTDC | 1 |
| de Sena, MO | 1 |
| Dantas, PB | 1 |
| Barbosa, AIDS | 1 |
| Holanda, VAD | 1 |
| Oliveira, JIN | 1 |
| Gavioli, EC | 1 |
| da Silva Junior, ED | 2 |
| Phelps, C | 1 |
| Chess-Williams, R | 14 |
| Moro, C | 3 |
| Hardy, CC | 1 |
| Keilich, SR | 1 |
| Harrison, AG | 1 |
| Knight, BE | 1 |
| Baker, DS | 1 |
| Smith, PP | 1 |
| Karaomerlioglu, I | 1 |
| Ozturk, N | 1 |
| Muderrisoglu, AE | 1 |
| Parikh, V | 1 |
| Scala, J | 1 |
| Patel, R | 1 |
| Corbi, C | 1 |
| Lo, D | 1 |
| Bochkov, YA | 1 |
| Kennedy, JL | 1 |
| Kurten, RC | 1 |
| Liggett, SB | 1 |
| Gern, JE | 1 |
| Koziol-White, CJ | 1 |
| Wang, KL | 1 |
| Hsia, SM | 1 |
| Wang, PS | 1 |
| Lin, PH | 1 |
| Tarhan, F | 1 |
| Çağlayan Duman, N | 1 |
| Özkula, S | 1 |
| Karaalp, A | 4 |
| Cangüven, Ö | 1 |
| Callewaert, G | 1 |
| Monteiro Carvalho Mori Da Cunha, MG | 1 |
| Dewulf, K | 2 |
| Albersen, M | 2 |
| Deprest, J | 1 |
| Mizutani, H | 1 |
| Sakakibara, F | 1 |
| Sasaki, E | 1 |
| Tinay, I | 2 |
| Celik, O | 1 |
| Sekerci, CA | 1 |
| Cadirci, S | 1 |
| Cevik, O | 1 |
| Oroglu, B | 1 |
| Sener, G | 3 |
| Tarcan, T | 4 |
| Manak, I | 1 |
| Gurney, AM | 1 |
| McCloskey, KD | 2 |
| Woolf, AS | 1 |
| Roberts, NA | 1 |
| Singh, N | 1 |
| Mizoguchi, S | 1 |
| Suzuki, T | 3 |
| Zabbarova, I | 2 |
| Ikeda, Y | 2 |
| Kanai, A | 2 |
| Chermansky, C | 1 |
| Yoshimura, N | 4 |
| Tyagi, P | 2 |
| Guo, HL | 1 |
| Peng, XF | 1 |
| Bao, XQ | 1 |
| Wang, L | 1 |
| Jia, ZM | 1 |
| Huang, YC | 2 |
| Zhou, JM | 1 |
| Xie, H | 1 |
| Chen, F | 2 |
| West, EG | 1 |
| Sellers, DJ | 4 |
| McDermott, C | 2 |
| Kawata, R | 1 |
| Hotta, Y | 1 |
| Maeda, K | 1 |
| Kataoka, T | 1 |
| Kimura, K | 3 |
| Azuma, YT | 3 |
| Suzuki, S | 2 |
| Nishiyama, K | 2 |
| Yamaguchi, T | 3 |
| Turner, AC | 1 |
| Powers, SA | 2 |
| Odom, MR | 1 |
| Pak, ES | 2 |
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| Magbagbeola, AO | 1 |
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| Gillespie, JS | 2 |
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| Widmark, E | 4 |
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| Arhan, P | 1 |
| Devroede, G | 1 |
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| Barbier, JP | 1 |
| Pellerin, D | 1 |
| Lafi, MA | 1 |
| Leake, LD | 1 |
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| Scott, LD | 1 |
| DeFlora, E | 1 |
| Amstutz, R | 2 |
| Karlén, B | 1 |
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| Scott, CW | 1 |
| Mumby, MC | 1 |
| Broadley, KJ | 3 |
| Broome, S | 1 |
| Paton, DM | 1 |
| Welford, LA | 1 |
| Cusack, NJ | 1 |
| Zacharias, J | 1 |
| Schiller, PW | 1 |
| Maziak, L | 1 |
| Nguyen, TM | 1 |
| Godin, J | 1 |
| Garcia, R | 1 |
| De Léan, A | 1 |
| Cantin, M | 1 |
| Foley, AJ | 1 |
| Moss, HE | 1 |
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| Giardinà, D | 1 |
| van Heuven-Nolsen, D | 1 |
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| Ahn, HY | 1 |
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| Fonnum, F | 3 |
| Beckett, WS | 1 |
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| Takuwa, Y | 2 |
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| Rasmussen, H | 3 |
| Lategan, TW | 1 |
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| Fujinuma, S | 2 |
| Kusunoki, M | 2 |
| Kantoh, M | 2 |
| Yamamura, T | 2 |
| Utsunomiya, J | 2 |
| Picchio, MT | 2 |
| Magura, IS | 1 |
| Murphey, KA | 1 |
| Khoyi, MA | 1 |
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| Lindeke, B | 1 |
| Gilani, SA | 1 |
| Cobbin, LB | 1 |
| Sahin, I | 1 |
| Zhou, YY | 1 |
| Tang, ZG | 1 |
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| He, JH | 1 |
| Chen, D | 1 |
| Hou, DY | 1 |
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| Carroll, FI | 1 |
| Abraham, P | 1 |
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| Richard, MM | 1 |
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| Witkin, JM | 1 |
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| Markowicz, ME | 1 |
| Lippe, IT | 1 |
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| Markus, RP | 1 |
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| Smith, PF | 1 |
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| Cutcher, A | 1 |
| Dunn, AM | 1 |
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| D'Agostino, G | 1 |
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| Kishimoto, T | 1 |
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| Hoppin, FG | 1 |
| Takishima, T | 1 |
| O'Malley, NA | 2 |
| Marceau-Day, ML | 1 |
| Mansour, S | 1 |
| Shepherd, MK | 1 |
| Shimada, T | 1 |
| Shimamura, K | 1 |
| Marshall, RW | 1 |
| Weston-Smith, P | 1 |
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| Mackenzie, JE | 1 |
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| Birnbaum, J | 1 |
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| de la Lande, I | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Investigation of the Suburothelial Myofibroblast Network and of Smooth Muscle Function and Control in the Continent and Incontinent Human Urinary Outflow Tract[NCT01227447] | 200 participants (Anticipated) | Observational | 2010-01-31 | Recruiting | |||
| Extracoporeal Shock Wave Therapy (ESWT) for the Treatment of Detrusor Underactivity/ Underactive Bladder (DU/UAB) - a Single Center, Randomized, Double-blind, Placebo-controlled, Prospective Study[NCT04161183] | 11 participants (Actual) | Interventional | 2019-10-15 | Completed | |||
| Can Acupoint Low Intensity Shockwave Therapy Improve Bladder Voiding Efficiency: A Pilot Study.[NCT06020963] | 100 participants (Anticipated) | Interventional | 2023-08-11 | Recruiting | |||
| Efficacy of Amoxicillin for Treatment of Enteral Nutrition Intolerance in Pediatric Intensive Care Unit[NCT05828758] | Phase 2/Phase 3 | 90 participants (Anticipated) | Interventional | 2023-04-24 | Recruiting | ||
| A Pilot Study to Assess the Safety and Efficacy of Solifenacin (VESIcare) for Improving Urinary and Bladder Functions in Patients Undergoing Radiation Therapy of the Prostate[NCT01777217] | Phase 4 | 8 participants (Actual) | Interventional | 2013-02-28 | Terminated (stopped due to Terminated) | ||
| Effectiveness of Oral Boldo in Improving Urinary Symptoms and Body Stability in Women Diagnosed With Overactive Bladder[NCT06162065] | Phase 1 | 10 participants (Anticipated) | Interventional | 2023-11-01 | Enrolling by invitation | ||
| A Randomized Trial of Bladder Instillations Versus Onabotulinumtoxin A for Treatment of Interstitial Cystitis/Bladder Pain Syndrome[NCT04401176] | Phase 2 | 58 participants (Actual) | Interventional | 2020-09-15 | Completed | ||
| Crossover Trial of Gluten and Gluten With Amylase-trypsin Inhibitors as Triggers of Gastrointestinal Symptoms in Patients With Irritable Bowel Syndrome[NCT03664531] | 34 participants (Anticipated) | Interventional | 2019-01-01 | Recruiting | |||
| Potential Biomarkers in the Study of Overactive Bladder in Women[NCT03516292] | 108 participants (Anticipated) | Observational | 2018-01-29 | Recruiting | |||
| Small Dose of Sugammadex Improves Muscle Function After Standard Neuromuscular Recovery (TOF 0.9)[NCT01101139] | Phase 4 | 300 participants (Actual) | Interventional | 2010-04-30 | Completed | ||
| Investigation of Miconazole as an Inhibitor of Endothelium-Derived Hyperpolarizing Factor[NCT00004575] | Phase 1 | 15 participants | Interventional | 2000-02-29 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
The AUASS score range is 1-7 (mild), 8-19 (moderate) and 20-35 (severe). The AUASS asks 7 questions scored 0-5, the scores are summed for the total score. (NCT01777217)
Timeframe: baseline and 16 weeks
| Intervention | Scores on a scale (Median) |
|---|---|
| Solifenacin Succinate | 9.4 |
| Placebo | 6.7 |
15 reviews available for carbachol and Muscle Contraction
| Article | Year |
|---|---|
Inflammation-induced airway smooth muscle responsiveness is strain dependent in mice.
Topics: Animals; Bradykinin; Carbachol; Inflammation; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; M | 2011 |
CALCIUM AND THE INITIATION OF CONTRACTION.
Topics: Acetylcholine; Adenosine Triphosphate; Calcium; Carbachol; Cardiac Glycosides; Electrophysiology; Ep | 1964 |
[Pharmacological and clinical profile of imidafenacin developed as a new therapeutic agent for overactive bladder].
Topics: Acetylcholine; Animals; Carbachol; Clinical Trials as Topic; Drug-Related Side Effects and Adverse R | 2008 |
The neuromuscular effects of lignocaine.
Topics: Acetylcholine; Animals; Carbachol; Lidocaine; Muscle Contraction; Neuromuscular Depolarizing Agents; | 1984 |
[Drug-receptor interactions in single smooth muscle cells].
Topics: Acetylcholine; Animals; Calcium; Carbachol; Cell Separation; Cells, Cultured; Colon; Dose-Response R | 1993 |
[Modulation of the voltage-dependent Ca2+ channels of smooth muscle by phosphorylation].
Topics: Animals; Calcium Channels; Carbachol; Colon; Guinea Pigs; Membrane Potentials; Muscle Contraction; M | 1993 |
[Isolation, configuration and contractile responses of single smooth muscle cells].
Topics: Acetylcholine; Animals; Carbachol; Cell Separation; Cells, Cultured; Collagenases; Dose-Response Rel | 1993 |
The significance of smooth and striated muscles in the sphincter function of the urethra in healthy women.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adult; Autonomic Nervous System; Carbachol; | 1995 |
[Transition of drug receptor mechanisms].
Topics: Animals; Calcium; Carbachol; Dioxanes; Muscle Contraction; Phenylephrine; Pilocarpine; Propylbenzily | 1992 |
Interaction of calcitonin gene-related peptides with pancreatic acinar cells and dispersed gastric smooth muscle cells.
Topics: Amylases; Animals; Calcitonin Gene-Related Peptide; Carbachol; Cyclic AMP; Guinea Pigs; In Vitro Tec | 1992 |
Modulation of the Ca(2+)-sensitivity in phasic and tonic smooth muscle.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Calcium; Carbachol; Dog | 1992 |
Role of alpha-adrenergic blockers in the treatment of benign prostatic hyperplasia.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Brimonidine Tartrate; Carbachol; Humans; Ma | 1990 |
Filament structure in contracted smooth muscle.
Topics: Actin Cytoskeleton; Actins; Adenosine Triphosphatases; Animals; Calcium Channel Blockers; Carbachol; | 1985 |
In-vivo and in-vitro responsiveness of bronchial smooth muscle.
Topics: Airway Resistance; Albuterol; Animals; Asthma; Atropine; Atropine Derivatives; Bronchi; Carbachol; D | 1986 |
On the muscarinic receptors in the urinary bladder and the putative subclassification of muscarinic receptors.
Topics: Adult; Aged; Animals; Carbachol; Cerebral Cortex; Denervation; Guinea Pigs; Humans; Hypertrophy; Ile | 1986 |
1 trial available for carbachol and Muscle Contraction
| Article | Year |
|---|---|
In vitro responses of gallbladder muscle from patients with acalculous biliary pain.
Topics: Adult; Aged; Carbachol; Cholecystitis; Cholelithiasis; Dose-Response Relationship, Drug; Female; Gal | 2000 |
2016 other studies available for carbachol and Muscle Contraction
| Article | Year |
|---|---|
Actions of two dopamine derivatives at adreno- and cholinoceptors.
Topics: Animals; Blood Pressure; Cats; Chickens; Dopamine; Female; Guinea Pigs; Heart Rate; In Vitro Techniq | 1979 |
Synthesis and cholinergic properties of N-aryl-2-[[[5-[(dimethylamino)methyl]-2-furanyl]methyl]thio]ethylamino analogs of ranitidine.
Topics: Acetylcholine; Animals; Brain; Butyrylcholinesterase; Cholinesterase Inhibitors; Drug Synergism; Ery | 1992 |
Urea and 2-imidazolidone derivatives of the muscarinic agents oxotremorine and N-methyl-N-(1-methyl-4-pyrrolidino-2-butynyl)acetamide.
Topics: Animals; Cerebral Cortex; Guinea Pigs; Ileum; Imidazoles; Molecular Structure; Muscarinic Antagonist | 1992 |
Synthesis and in vitro biological profile of all four isomers of the potent muscarinic agonist 3-(3-methyl-1,2,4-oxadiazol-5-yl)-1-azabicyclo[2.2.1]heptane.
Topics: Animals; Binding, Competitive; Bridged Bicyclo Compounds, Heterocyclic; Electrophysiology; Ganglia, | 1992 |
Resolved pyrrolidine, piperidine, and perhydroazepine analogues of the muscarinic agent N-methyl-N-(1-methyl-4-pyrrolidino-2-butynyl)acetamide.
Topics: Animals; Azepines; Binding, Competitive; Cerebral Cortex; Chemical Phenomena; Chemistry; Guinea Pigs | 1990 |
Conformationally restricted analogues of the muscarinic agent N-methyl-N-(1-methyl-4-pyrrolidino-2-butynyl)acetamide.
Topics: Animals; Biological Assay; Cerebral Cortex; Chemical Phenomena; Chemistry; Guinea Pigs; Ileum; Mice; | 1989 |
Tertiary 3- and 4-haloalkylamine analogues of oxotremorine as prodrugs of potent muscarinic agonists.
Topics: Analgesia; Animals; Guinea Pigs; Ileum; In Vitro Techniques; Indicators and Reagents; Kinetics; Magn | 1988 |
Dimethylsulfonium and thiolanium analogues of the muscarinic agent oxotremorine.
Topics: Animals; Guinea Pigs; Ileum; In Vitro Techniques; Indicators and Reagents; Muscle Contraction; Onium | 1988 |
Derivatives of the muscarinic agent N-methyl-N-(1-methyl-4-pyrrolidino-2-butynyl)acetamide.
Topics: Acetamides; Animals; Fluoroacetates; Guinea Pigs; Ileum; In Vitro Techniques; Magnetic Resonance Spe | 1988 |
Resolution, absolute configuration, and cholinergic enantioselectivity of (+)- and (-)-cis-2-methyl-5-[(dimethylamino)methyl]-1,3-oxathiolane methiodide.
Topics: Animals; Anura; Dimethylamines; Guinea Pigs; Heterocyclic Compounds; Male; Muscarine; Muscle Contrac | 1986 |
Highly chiral muscarinic ligands: the discovery of (2S,2'R,3'S,5'R)-1-methyl-2-(2-methyl-1,3-oxathiolan-5-yl)pyrrolidine 3-sulfoxide methyl iodide, a potent, functionally selective, M2 partial agonist.
Topics: Animals; Atrial Function, Left; CHO Cells; Cricetinae; Cricetulus; Cyclic S-Oxides; Guinea Pigs; Hum | 2006 |
Combined agonists act synergistically to increase mucociliary clearance in a cystic fibrosis airway model.
Topics: Animals; Carbachol; Colforsin; Cystic Fibrosis; Disease Models, Animal; Drug Synergism; Drug Therapy | 2021 |
Adiponectin and the regulation of gastric content volume in the newborn rat.
Topics: Adiponectin; Animals; Animals, Newborn; Carbachol; Gastric Emptying; Muscle Contraction; Muscle, Smo | 2021 |
Cellular Mechanism Underlying the Facilitation of Contractile Response Induced by Tumor Necrosis Factor-α in Mouse Tracheal Smooth Muscle.
Topics: Animals; Calcium Channels, L-Type; Carbachol; Male; Mice; Muscle Contraction; Muscle, Smooth; Phosph | 2022 |
Validation of Fenoterol to Study β2-Adrenoceptor Function in the Rat Urinary Bladder.
Topics: Adrenergic beta-2 Receptor Agonists; Adrenergic beta-Antagonists; Aminophenols; Animals; Carbachol; | 2022 |
A novel ex vivo model for critical illness neuromyopathy using freshly resected human colon smooth muscle.
Topics: Aged; Biological Assay; Carbachol; Colon; Critical Illness; Electric Stimulation; Electrophysiology; | 2021 |
Modulation of carbachol-induced Ca
Topics: Animals; Calcium; Carbachol; Colforsin; Dinoprostone; Mice; Muscle Contraction; Muscle, Smooth; Myoc | 2022 |
Inhibition of Full Smooth Muscle Contraction in Isolated Human Detrusor Tissues by Mirabegron Is Limited to Off-Target Inhibition of Neurogenic Contractions.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetanilides; Carbachol; Endothe | 2022 |
Neuropilin 2 Is a Novel Regulator of Distal Colon Contractility.
Topics: Animals; Carbachol; Colon; Gastrointestinal Motility; Humans; Mice; Mice, Knockout; Muscle Contracti | 2022 |
Airway Smooth Muscles Contractions in Metabolic Syndrome.
Topics: Albuterol; Animals; Bronchi; Bronchoconstrictor Agents; Carbachol; Carbohydrates; Metabolic Syndrome | 2022 |
Starving a Cell Promotes Airway Smooth Muscle Relaxation: Inhibition of Glycolysis Attenuates Excitation-Contraction Coupling.
Topics: Adenosine Triphosphate; Asthma; Carbachol; Cells, Cultured; Glucose; Glycolysis; Humans; Lung; Muscl | 2023 |
Evaluation of Disorders of Contractile Activity of Smooth Muscle Tissues in 9-Month-Old Rats with a Model of Autism.
Topics: Adenosine Triphosphate; Animals; Autistic Disorder; Carbachol; Electric Stimulation; Male; Muscle Co | 2023 |
The inhibitory effect of escitalopram on mouse detrusor contractility: The role of L-type calcium channels.
Topics: Animals; Calcium Channels, L-Type; Carbachol; Escitalopram; Mice; Molecular Docking Simulation; Musc | 2023 |
The TMEM16A blockers benzbromarone and MONNA cause intracellular Ca
Topics: Animals; Benzbromarone; Caffeine; Calcium; Carbachol; Chloride Channels; Mice; Muscle Contraction; M | 2023 |
Focal adhesion kinase activation is involved in contractile stimulation-induced detrusor muscle contraction in mice.
Topics: Animals; Carbachol; Dimethyl Sulfoxide; Focal Adhesion Protein-Tyrosine Kinases; Mice; Muscle Contra | 2023 |
Comparative Assessment of Disturbances of Contractions of the Isolated Uterus in 3- and 9-Month-Old Rats with a Model of Autism.
Topics: Adenosine Triphosphate; Animals; Autism Spectrum Disorder; Autistic Disorder; Carbachol; Electric St | 2023 |
Smooth muscle contraction of the fundus of stomach, duodenum and bladder from mice exposed to a stress-based model of depression.
Topics: Animals; Carbachol; Depression; Duodenum; Isoproterenol; Male; Mice; Muscle Contraction; Stomach; Ur | 2023 |
Ageing influences detrusor contractions to prostaglandin, angiotensin, histamine and 5-HT (serotonin), independent to the Rho kinase and extracellular calcium pathways.
Topics: Aging; Angiotensins; Animals; Calcium; Calcium, Dietary; Carbachol; Dinoprostone; Histamine; Muscle | 2023 |
The aging bladder phenotype is not the direct consequence of bladder aging.
Topics: Adrenergic beta-Agonists; Aging; Animals; Carbachol; Cholinergic Agonists; Electric Stimulation; Fem | 2019 |
Normalization of organ bath contraction data for tissue specimen size: does one approach fit all?
Topics: Animals; Aorta; Carbachol; In Vitro Techniques; Male; Muscle Contraction; Phenylephrine; Potassium C | 2020 |
Rhinovirus C15 Induces Airway Hyperresponsiveness via Calcium Mobilization in Airway Smooth Muscle.
Topics: Asthma; Calcium Signaling; Carbachol; Cells, Cultured; Chemokine CXCL10; Enterovirus; Enterovirus In | 2020 |
Disturbed Gastrointestinal Contractility in a Polycystic Ovary Syndrome Rat Model.
Topics: Acetylcholine; Animals; Calcium Signaling; Carbachol; Colon; Dihydrotestosterone; Disease Models, An | 2020 |
Topics: Animals; Carbachol; Female; Humans; Muscle Contraction; Muscle, Smooth; Oxytocin; Rats; Rats, Wistar | 2020 |
Simulated vaginal delivery causes transients vaginal smooth muscle hypersensitivity and urethral sphincter dysfunction.
Topics: Animals; Carbachol; Cholinergic Agonists; Delivery, Obstetric; Female; Models, Animal; Muscle Contra | 2020 |
TAS-303 Ameliorates Carbachol-Induced Detrusor Overactivity in Rats, Revealing Its Therapeutic Potential for Overactive Bladder.
Topics: Adrenergic beta-3 Receptor Antagonists; Animals; Atropine; Carbachol; Dose-Response Relationship, Dr | 2020 |
Hyperbaric oxygen therapy prevents subarachnoid hemorrhage-induced apoptosis and impaired contractility of the rabbit bladder.
Topics: Animals; Apoptosis; Carbachol; Caspase 3; Disease Models, Animal; Hyperbaric Oxygenation; Male; Musc | 2020 |
Dysfunctional bladder neurophysiology in urofacial syndrome Hpse2 mutant mice.
Topics: Adrenergic alpha-1 Receptor Agonists; Animals; Carbachol; Electric Stimulation; Facies; Glucuronidas | 2020 |
Excitatory effect of acotiamide on rat and human bladder: Implications for underactive bladder treatment.
Topics: Animals; Benzamides; Carbachol; Electric Stimulation; Humans; Male; Muscle Contraction; Rats, Spragu | 2020 |
Bladder reconstruction using autologous smooth muscle cell sheets grafted on a pre-vascularized capsule.
Topics: Animals; Carbachol; Cell Culture Techniques; Coculture Techniques; Endothelial Cells; Feasibility St | 2020 |
Bladder overactivity induced by psychological stress in female mice is associated with enhanced bladder contractility.
Topics: Acetylcholine; Animals; Carbachol; Corticosterone; Female; Mice; Mice, Inbred C57BL; Muscarinic Agon | 2021 |
Effects of High Salt Intake on Detrusor Muscle Contraction in Dahl Salt-Sensitive Rats.
Topics: Animals; Carbachol; Cholinergic Agonists; Dose-Response Relationship, Drug; Electric Stimulation; Is | 2021 |
Gastrointestinal motility modulation by stress is associated with reduced smooth muscle contraction through specific transient receptor potential channel.
Topics: Animals; Carbachol; Electric Stimulation; Gastrointestinal Motility; Ileum; Mice; Muscle Contraction | 2021 |
Impact of prostatic radiation therapy on bladder contractility and innervation.
Topics: Animals; Carbachol; Male; Muscle Contraction; Muscle, Smooth; Rats; Rats, Sprague-Dawley; Urinary Bl | 2021 |
Developmental changes in contractile responses to cholinergic stimuli: role of calcium sensitization and related pathways.
Topics: Age Factors; Animals; Animals, Newborn; Calcium Compounds; Calcium Signaling; Carbachol; Cholinergic | 2017 |
Effects of vesical and perfusion pressure on perfusate flow, and flow on vesical pressure, in the isolated perfused working pig bladder reveal a potential mechanism for the regulation of detrusor compliance.
Topics: Animals; Carbachol; Male; Muscle Contraction; Muscle, Smooth; Pressure; Swine; Urethra; Urinary Blad | 2018 |
Extracellular acidosis selectively inhibits pharmacomechanical coupling induced by carbachol in strips of rat gastric fundus.
Topics: Acidosis; Animals; Calcium Signaling; Carbachol; Cholinergic Agonists; Dose-Response Relationship, D | 2017 |
The expression and functional activities of smooth muscle myosin and non-muscle myosin isoforms in rat prostate.
Topics: Amino Acid Sequence; Animals; Carbachol; Epithelial Cells; Male; Muscle Contraction; Myocytes, Smoot | 2018 |
Rac1 modulates G-protein-coupled receptor-induced bronchial smooth muscle contraction.
Topics: Animals; Bronchi; Carbachol; Endothelin-1; Male; Marine Toxins; Muscle Contraction; Muscle, Smooth; | 2018 |
Human small bowel as a useful tool to investigate smooth muscle effects of potential therapeutics in organophosphate poisoning.
Topics: Aged; Aged, 80 and over; Animals; Antidotes; Carbachol; Cholinesterase Reactivators; Dose-Response R | 2018 |
Effects of selective α
Topics: Adrenergic alpha-2 Receptor Agonists; Animals; Brimonidine Tartrate; Bronchi; Carbachol; Electric St | 2018 |
Inhalation anaesthetic isoflurane inhibits the muscarinic cation current and carbachol-induced gastrointestinal smooth muscle contractions.
Topics: Anesthetics, Inhalation; Animals; Calcium; Carbachol; Electrophysiological Phenomena; Intestines; In | 2018 |
β3-adrenoceptor agonists inhibit carbachol-evoked Ca
Topics: Adrenergic beta-3 Receptor Agonists; Adrenergic beta-Agonists; Animals; Calcium; Carbachol; Choliner | 2018 |
Testosterone induces hyporesponsiveness by interfering with IP
Topics: Amino Acid Sequence; Animals; Calcium; Calcium Channels; Carbachol; Genome; Guinea Pigs; Histamine; | 2018 |
Effects of chlorogenic acid on carbachol-induced contraction of mouse urinary bladder.
Topics: 1-Methyl-3-isobutylxanthine; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenylyl Cyclases; Anim | 2018 |
Concomitant alteration in number and affinity of P
Topics: Adenosine Triphosphate; Animals; Carbachol; Cholinergic Agonists; Diabetes Mellitus, Experimental; E | 2018 |
Role of rho-kinase (ROCK) in tonic but not phasic contraction in the frog stomach smooth muscle.
Topics: Amides; Animals; Atropine; Carbachol; Gastric Mucosa; Muscle Contraction; Muscle, Smooth; Nifedipine | 2018 |
Effects of fetal hypothyroidism on uterine smooth muscle contraction and structure of offspring rats.
Topics: Animals; Carbachol; Female; Fetus; Hypothyroidism; Muscle Contraction; Muscle, Smooth; Oxytocin; Pre | 2018 |
Inhibition of ZERO-BK by PKC is involved in carbachol-induced enhancement of rat colon smooth muscle motility.
Topics: Animals; Benzimidazoles; Carbachol; Cholinergic Agonists; Colon; Gastrointestinal Motility; HEK293 C | 2018 |
Acute radiation impacts contractility of guinea-pig bladder strips affecting mucosal-detrusor interactions.
Topics: Adenosine Triphosphate; Animals; Atropine; Calcium Signaling; Carbachol; Dose-Response Relationship, | 2018 |
Aerobic metabolism on muscle contraction in porcine gastric smooth muscle.
Topics: Adenosine Triphosphate; Aerobiosis; Animals; Carbachol; Female; Gastric Mucosa; Male; Muscle Contrac | 2018 |
Bronchodilator effects of Lignosus rhinocerotis extract on rat isolated airways is linked to the blockage of calcium entry.
Topics: Animals; Asthma; Bronchi; Bronchodilator Agents; Calcium; Carbachol; Male; Muscle Contraction; Organ | 2018 |
Adreno-muscarinic synergy in the male human urinary outflow tract.
Topics: Adrenergic alpha-Agonists; Aged; Aged, 80 and over; Carbachol; Female; Humans; Male; Middle Aged; Mu | 2018 |
Contractile responses in intact and mucosa-denuded human ureter-a comparison with urinary bladder detrusor preparations.
Topics: Adrenergic alpha-Agonists; Aged; Carbachol; Female; Humans; In Vitro Techniques; Male; Middle Aged; | 2018 |
Rho Kinase and Protein Kinase C Pathways are Responsible for Enhanced Carbachol Contraction in Permeabilized Detrusor in a Rat Model of Cystitis.
Topics: Amides; Animals; Carbachol; Cholinergic Agonists; Cystitis, Interstitial; Enzyme Inhibitors; Heparin | 2018 |
Possible antagonistic effects of the TRPC4 channel blocker ML204 on M
Topics: Animals; Atrial Fibrillation; Carbachol; Japan; Male; Mice; Muscarinic Antagonists; Muscle Contracti | 2018 |
Characterization of voiding function and structural bladder changes in a rat model of neurogenic underactive bladder disease.
Topics: Animals; Carbachol; Gene Expression; Male; Muscarinic Agonists; Muscle Contraction; Myocytes, Smooth | 2018 |
Obesity increases airway smooth muscle responses to contractile agonists.
Topics: Adult; Asthma; Calcium; Carbachol; Cardiotonic Agents; Case-Control Studies; Cells, Cultured; Female | 2018 |
Deletion of IP
Topics: Animals; Carbachol; Cholinergic Agonists; Colon; Disease Models, Animal; Gastrointestinal Transit; I | 2019 |
Heating-induced contraction in airways smooth muscle: A possible causative factor of exercise-induced bronchoconstriction.
Topics: Animals; Bronchoconstriction; Carbachol; Cholinergic Agonists; Cold Temperature; Electromyography; F | 2019 |
Intestinal, urinary and uterine antispasmodic effects of isoespintanol, metabolite from Oxandra xylopioides leaves.
Topics: Animals; Annonaceae; Calcium; Carbachol; Female; Intestines; Muscle Contraction; Muscle, Smooth; Par | 2018 |
Involvement of transient receptor potential melastatin 4 channels in the resting membrane potential setting and cholinergic contractile responses in mouse detrusor and ileal smooth muscles.
Topics: Animals; Carbachol; Cholinergic Agents; Dose-Response Relationship, Drug; Female; Ileum; Male; Membr | 2019 |
Prestrain and cholinergic receptor-dependent differential recruitment of mechanosensitive energy loss and energy release elements in airway smooth muscle.
Topics: Animals; Bronchoconstriction; Carbachol; Cattle; Cholinergic Agents; Lung; Muscle Contraction; Muscl | 2019 |
The effects of ATP on the contractions of rat and mouse fast skeletal muscle.
Topics: Adenosine Triphosphate; Animals; Carbachol; Cold Temperature; Electric Stimulation; Excitatory Posts | 2019 |
Up-regulation of Rac1 in the bronchial smooth muscle of murine experimental asthma.
Topics: Animals; Asthma; Bronchi; Carbachol; Disease Models, Animal; Humans; Male; Mice; Muscle Contraction; | 2019 |
Long-term functional change of cryoinjury-induced detrusor underactivity and effects of extracorporeal shock wave therapy in a rat model.
Topics: Actins; Animals; Brain-Derived Neurotrophic Factor; Calcitonin Gene-Related Peptide; Carbachol; Chol | 2019 |
Long-term functional change of cryoinjury-induced detrusor underactivity and effects of extracorporeal shock wave therapy in a rat model.
Topics: Actins; Animals; Brain-Derived Neurotrophic Factor; Calcitonin Gene-Related Peptide; Carbachol; Chol | 2019 |
Long-term functional change of cryoinjury-induced detrusor underactivity and effects of extracorporeal shock wave therapy in a rat model.
Topics: Actins; Animals; Brain-Derived Neurotrophic Factor; Calcitonin Gene-Related Peptide; Carbachol; Chol | 2019 |
Long-term functional change of cryoinjury-induced detrusor underactivity and effects of extracorporeal shock wave therapy in a rat model.
Topics: Actins; Animals; Brain-Derived Neurotrophic Factor; Calcitonin Gene-Related Peptide; Carbachol; Chol | 2019 |
Pharmacological modulation of the spatiotemporal disposition of micromotions in the intact resting urinary bladder of the rabbit; their pattern is under both myogenic and autonomic control.
Topics: Adrenergic beta-Agonists; Amides; Animals; Carbachol; Carbenoxolone; Cholinergic Agonists; Isoproter | 2019 |
Chronic high-fat diet decreased detrusor mitochondrial respiration and increased nerve-mediated contractions.
Topics: Adiposity; Animals; Carbachol; Diet, High-Fat; Electric Stimulation; Hydrogen Peroxide; Male; Mice; | 2019 |
Detrusor contractility to parasympathetic mediators is differentially altered in the compensated and decompensated states of diabetic bladder dysfunction.
Topics: Adenosine Triphosphate; Animals; Carbachol; Cholinergic Agonists; Diabetes Mellitus, Experimental; D | 2019 |
Tadalafil, a phosphodiesterase type 5 inhibitor, restores urethra and detrusor function in the initial phase of diabetes in rats.
Topics: Animals; Carbachol; Diabetes Mellitus, Experimental; Electric Stimulation; Female; Muscle Contractio | 2019 |
Increased Rac1 Activation in the Enhanced Carbachol-Induced Bronchial Smooth Muscle Contraction of Repeatedly Antigen-Challenged Mice.
Topics: Aminoquinolines; Animals; Antigens; Asthma; Bronchi; Carbachol; Guanine Nucleotide Exchange Factors; | 2019 |
The effects of cannabidiol on the antigen-induced contraction of airways smooth muscle in the guinea-pig.
Topics: Airway Obstruction; Animals; Arachidonic Acids; Bronchi; Cannabidiol; Cannabinoids; Carbachol; Endoc | 2013 |
Influence of phosphodiesterases on basal and 5-HT₄ receptor facilitated cholinergic contractility in pig descending colon.
Topics: Animals; Carbachol; Cholinergic Neurons; Colon, Descending; Electric Stimulation; In Vitro Technique | 2013 |
Histamine, carbachol, and serotonin induce hyperresponsiveness to ATP in guinea pig tracheas: involvement of COX-2 pathway.
Topics: Adenosine Triphosphate; Animals; Carbachol; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inh | 2013 |
The effect of rabeprazole on LES tone in experimental rat model.
Topics: Animals; Carbachol; Esophageal Sphincter, Lower; Gastroesophageal Reflux; In Vitro Techniques; Muscl | 2013 |
Phasic contractions in urinary bladder from juvenile versus adult pigs.
Topics: Aging; Animals; Benzamides; Carbachol; Dose-Response Relationship, Drug; Female; Imatinib Mesylate; | 2013 |
Pharmacological study of a new Asp49 phospholipase A(2) (Bbil-TX) isolated from Bothriopsis bilineata smargadina (forest viper) venom in vertebrate neuromuscular preparations.
Topics: Acetophenones; Animals; Bothrops; Carbachol; Chickens; Diaphragm; Male; Mice; Miniature Postsynaptic | 2013 |
PTHrP is endogenous relaxant for spontaneous smooth muscle contraction in urinary bladder of female rat.
Topics: Animals; Carbachol; Cells, Cultured; Cholinergic Agonists; Cyclic AMP; Female; Gene Expression Profi | 2013 |
Spasmolytic effect of caulerpine involves blockade of Ca²⁺ influx on guinea pig ileum.
Topics: Animals; Calcium; Calcium Channels; Carbachol; Caulerpa; Dose-Response Relationship, Drug; Female; G | 2013 |
Bladder contractility is modulated by Kv7 channels in pig detrusor.
Topics: Animals; Carbachol; Electric Stimulation; Gene Expression Regulation; In Vitro Techniques; KCNQ Pota | 2013 |
Expression of Hsp27 correlated with rat detrusor contraction after acute urinary retention.
Topics: Animals; Blotting, Western; Carbachol; Female; Fluorescent Antibody Technique; Gene Expression Regul | 2013 |
Gap junction expression and the effects of gap junction inhibitors in overactive bladder models: does ovariectomy have a role?
Topics: Analysis of Variance; Animals; Blotting, Western; Carbachol; Connexin 43; Disease Models, Animal; Fe | 2013 |
Differential regulation of muscarinic M2 and M3 receptor signaling in gastrointestinal smooth muscle by caveolin-1.
Topics: Animals; Carbachol; Caveolae; Caveolin 1; Cells, Cultured; Cholinergic Agonists; Cyclic AMP; Gastric | 2013 |
Gastric body cholinergic contractile signal transduction in M2 and M3 receptor knockout mice.
Topics: Animals; Carbachol; Enzyme Inhibitors; Gastric Mucosa; Mice; Mice, Knockout; Muscle Contraction; Mus | 2013 |
Beta-arrestin2 is involved in the increase of distal colonic contraction in diabetic rats.
Topics: Animals; Arrestins; beta-Arrestins; Carbachol; Cholinergic Agonists; Colon; Diabetes Mellitus, Exper | 2013 |
Functional characterization of acetylcholine receptors and calcium signaling in rat testicular capsule contraction.
Topics: Acetylcholine; Animals; Calcium; Calcium Channel Blockers; Calcium Signaling; Carbachol; Cholinergic | 2013 |
Studies on tracheorelaxant and anti-inflammatory activities of rhizomes of Polygonatum verticillatum.
Topics: Animals; Anti-Inflammatory Agents; Calcium Channel Blockers; Carbachol; Carrageenan; Edema; Female; | 2013 |
Characterization of bladder function in a cannabinoid receptor type 2 knockout mouse in vivo and in vitro.
Topics: Animals; Cannabinoids; Carbachol; Cholinergic Agonists; Electric Stimulation; Female; In Vitro Techn | 2014 |
The inhibitory effects of antimuscarinic autoantibodies in the sera of primary Sjogren syndrome patients on the gastrointestinal motility.
Topics: Animals; Autoantibodies; Carbachol; Cholinergic Agonists; Colon; Diamines; Dose-Response Relationshi | 2013 |
Stress-strain analysis of jejunal contractility in response to flow and ramp distension in type 2 diabetic GK rats: effect of carbachol stimulation.
Topics: Animals; Carbachol; Cholinergic Agonists; Diabetes Mellitus, Type 2; Elastic Modulus; Gastrointestin | 2013 |
Age-related alterations in regeneration of the urinary bladder after subtotal cystectomy.
Topics: Aging; Animals; Blood Vessels; Carbachol; Cell Proliferation; Collagen; Cystectomy; Female; In Vitro | 2013 |
Bladder function in a cannabinoid receptor type 1 knockout mouse.
Topics: Animals; Cannabinoid Receptor Antagonists; Carbachol; Female; Mice; Mice, Inbred C57BL; Mice, Knocko | 2014 |
Tonic and phasic smooth muscle contraction is not regulated by the PKCα - CPI-17 pathway in swine stomach antrum and fundus.
Topics: Animals; Biomechanical Phenomena; Carbachol; Gastric Fundus; Muscle Contraction; Muscle, Smooth; Myo | 2013 |
Ureterovesical junction obstruction causes increment in smooth muscle contractility, and cholinergic and adrenergic activity in distal ureter of rabbits.
Topics: Adrenergic Agonists; Adrenergic Fibers; Animals; Carbachol; Cholinergic Agonists; Cholinergic Fibers | 2013 |
TRK-380, a novel selective human β3-adrenoceptor agonist, ameliorates formalin-induced pollakiuria in rats and carbachol-induced bladder contraction in dogs.
Topics: Adrenergic beta-3 Receptor Agonists; Animals; Carbachol; Cholinergic Agonists; Dogs; Female; Formald | 2013 |
Age-dependent contribution of Rho kinase in carbachol-induced contraction of human detrusor smooth muscle in vitro.
Topics: Aged; Aged, 80 and over; Aging; Carbachol; Female; Humans; Male; Middle Aged; Muscle Contraction; Mu | 2014 |
Berberine improves neurogenic contractile response of bladder detrusor muscle in streptozotocin-induced diabetic rats.
Topics: Adenosine Triphosphate; Animals; Berberine; Carbachol; Diabetes Mellitus, Experimental; Electric Sti | 2013 |
Arginine vasopressin, via activation of post-junctional V1 receptors, induces contractile effects in mouse distal colon.
Topics: Animals; Arginine Vasopressin; Atropine; Calcium Channel Blockers; Carbachol; Cholinergic Agonists; | 2013 |
Do β-adrenoceptor agonists induce homologous or heterologous desensitization in rat urinary bladder?
Topics: Adrenergic beta-2 Receptor Agonists; Adrenergic beta-3 Receptor Agonists; Adrenergic beta-Agonists; | 2014 |
Purinergic and muscarinic modulation of ATP release from the urothelium and its paracrine actions.
Topics: Adenosine Triphosphate; Aged; Aging; Animals; Brefeldin A; Calcium; Carbachol; Carbenoxolone; Exocyt | 2014 |
Enhanced nicotinic receptor mediated relaxations in gastroesophageal muscle fibers from Barrett's esophagus patients.
Topics: Adult; Barrett Esophagus; Bethanechol; Carbachol; Cholinergic Agonists; Esophagus; Female; Humans; M | 2014 |
Brain-derived neurotrophic factor enhances cholinergic contraction of longitudinal muscle of rabbit intestine via activation of phospholipase C.
Topics: Animals; Brain-Derived Neurotrophic Factor; Carbachol; Cholinergic Agonists; Dose-Response Relations | 2014 |
Effects of chronic treatment with cilostazol, a phosphodiesterase 3 inhibitor, on female rat bladder in a partial bladder outlet obstruction model.
Topics: Animals; Carbachol; Cilostazol; Disease Models, Animal; Electric Stimulation; Female; Muscle Contrac | 2014 |
Chronic ketamine treatment-induced changes in contractility characteristics of the mouse detrusor.
Topics: Analgesics; Animals; Carbachol; Electric Stimulation; In Vitro Techniques; Ketamine; Male; Mice; Mic | 2014 |
Pantoprazole decreases gastroesophageal muscle tone in newborn rats via rho-kinase inhibition.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Animals; Animals, Newborn; Carbachol; Dose-Response Relatio | 2014 |
Stimulation of large-conductance calcium-activated potassium channels inhibits neurogenic contraction of human bladder from patients with urinary symptoms and reverses acetic acid-induced bladder hyperactivity in rats.
Topics: Acetic Acid; Adult; Aged; Animals; Carbachol; Electric Stimulation; Female; Humans; Large-Conductanc | 2014 |
Potent airway smooth muscle relaxant effect of cynatratoside B, a steroidal glycoside isolated from Cynanchum stauntonii.
Topics: Animals; Carbachol; Cynanchum; Dose-Response Relationship, Drug; Glycosides; Hong Kong; Male; Molecu | 2014 |
Pharmacological profile of DA-6886, a novel 5-HT4 receptor agonist to accelerate colonic motor activity in mice.
Topics: Animals; Benzamides; Carbachol; Colon; Esophagus; Gastrointestinal Motility; Loperamide; Male; Mice, | 2014 |
Nicotinic receptor subtypes mediating relaxation of the normal human clasp and sling fibers of the upper gastric sphincter.
Topics: Adult; Bethanechol; Carbachol; Esophageal Sphincter, Lower; Female; Gastric Mucosa; Humans; Male; Mi | 2014 |
Diabetes attenuates urothelial modulation of detrusor contractility and spontaneous activity.
Topics: Animals; Anthracenes; Carbachol; Carbamates; Cholinergic Agonists; Diabetes Mellitus, Experimental; | 2014 |
Macroscopic electrical propagation in the guinea pig urinary bladder.
Topics: Anesthetics, Local; Animals; Calcium Channel Blockers; Carbachol; Cholinergic Agonists; Electric Con | 2014 |
Neonatal mouse ileum: functional properties and protein composition of the contractile machinery.
Topics: Adaptation, Physiological; Age Factors; Animals; Animals, Newborn; Biomechanical Phenomena; Calcium; | 2014 |
Antispasmodic and myorelaxant effects of the flavoring agent methyl cinnamate in gut: potential inhibition of tyrosine kinase.
Topics: Acetic Acid; Animals; Calcium; Calcium Channel Blockers; Carbachol; Cinnamates; Colitis; Colon; Duod | 2014 |
Effects of menthol on circular smooth muscle of human colon: analysis of the mechanism of action.
Topics: Aged; Aged, 80 and over; Calcium Channel Blockers; Calcium Channels, L-Type; Carbachol; Colon; Elect | 2014 |
Functional properties and connective tissue content of pediatric human detrusor muscle.
Topics: Adenosine Triphosphate; Adult; Biomechanical Phenomena; Calcium; Carbachol; Child, Preschool; Connec | 2014 |
PDE4 and PDE5 regulate cyclic nucleotide contents and relaxing effects on carbachol-induced contraction in the bovine abomasum.
Topics: Abomasum; Animals; Carbachol; Cattle; Cholinergic Agonists; Cyclic Nucleotide Phosphodiesterases, Ty | 2015 |
Menthol inhibits detrusor contractility independently of TRPM8 activation.
Topics: Animals; Calcium Channel Blockers; Calcium Chloride; Carbachol; Cells, Cultured; Electric Stimulatio | 2014 |
The Role of Rac1 on Carbachol-induced Contractile Activity in Detrusor Smooth Muscle from Streptozotocin-induced Diabetic Rats.
Topics: Animals; Blood Glucose; Body Weight; Carbachol; Diabetes Complications; Diabetes Mellitus, Experimen | 2015 |
Izalpinin from fruits of Alpinia oxyphylla with antagonistic activity against the rat bladder contractility.
Topics: Alpinia; Carbachol; Cholinergic Agonists; Flavonoids; Fruit; Muscarinic Antagonists; Muscle Contract | 2014 |
ERK and p38MAPK pathways regulate myosin light chain phosphatase and contribute to Ca2+ sensitization of intestinal smooth muscle contraction.
Topics: Animals; Calcium; Carbachol; Cholinergic Agonists; Extracellular Signal-Regulated MAP Kinases; Ileum | 2015 |
β-Adrenoceptor-Mediated Relaxation of Carbachol-Pre-Contracted Mouse Detrusor.
Topics: Aminophenols; Animals; Carbachol; Cholinergic Agonists; Colforsin; Homozygote; Imidazoles; Isoproter | 2015 |
Enhanced urothelial ATP release and contraction following intravesical treatment with the cytotoxic drug, doxorubicin.
Topics: Adenosine Triphosphate; Administration, Intravesical; Animals; Antibiotics, Antineoplastic; Carbacho | 2015 |
Contractile profile of esophageal and gastric fundus strips in experimental doxorubicin-induced esophageal atresia.
Topics: Animals; Antibiotics, Antineoplastic; Carbachol; Cholinergic Agonists; Disease Models, Animal; Doxor | 2015 |
Estrogen regulates the expression of small-conductance Ca-activated K+ channels in colonic smooth muscle cells.
Topics: Actins; Animals; Apamin; Carbachol; Colon; Dimethyl Sulfoxide; Estradiol; Estrogen Receptor Antagoni | 2015 |
Increased Rho-kinase-mediated prostate contractions associated with impairment of β-adrenergic-cAMP-signaling pathway by chronic nitric oxide deficiency.
Topics: Adenosine Triphosphate; Amides; Animals; Carbachol; Cyclic AMP; Cyclic GMP; Dose-Response Relationsh | 2015 |
Effects of Amoxicillin and Clavulanic Acid on the Spontaneous Mechanical Activity of Juvenile Rat Duodenum.
Topics: Amoxicillin; Animals; Anti-Bacterial Agents; beta-Lactamase Inhibitors; Carbachol; Clavulanic Acid; | 2015 |
Role of various kinases in muscarinic M3 receptor-mediated contraction of longitudinal muscle of rat colon.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amides; Animals; Benzimidazoles; Calcium-Calmodulin-D | 2014 |
Force-inhibiting effect of Ser/Thr protein phosphatase 2A inhibitors on bovine ciliary muscle.
Topics: Animals; Calcium; Carbachol; Cattle; Ciliary Body; Enzyme Inhibitors; In Vitro Techniques; Ionomycin | 2015 |
Effects of papaverine on carbachol- and high K+ -induced contraction in the bovine abomasum.
Topics: Abomasum; Adjuvants, Immunologic; Animals; Carbachol; Cattle; Cholinergic Agonists; Colforsin; Muscl | 2015 |
Relaxant effects of a hydroalcoholic extract of Ruta graveolens on isolated rat tracheal rings.
Topics: Animals; Carbachol; Cholinergic Agents; Chromatography, Liquid; Furocoumarins; In Vitro Techniques; | 2015 |
Validation of ethnopharmacological uses of Heliotropium strigosum Willd. as spasmolytic, bronchodilator and vasorelaxant remedy.
Topics: Animals; Aorta; Bronchodilator Agents; Carbachol; Ethnopharmacology; Heliotropium; Jejunum; Male; Mu | 2015 |
Time-dependent changes in inhibitory action of lipopolysaccharide on intestinal motility in rat.
Topics: Alprostadil; Animals; Carbachol; Cyclooxygenase 2; Dinoprostone; Gastrointestinal Motility; Gene Exp | 2015 |
Contractile function of smooth muscle retained after overnight storage.
Topics: Animals; Carbachol; Colforsin; Endothelium, Vascular; Isoproterenol; Male; Models, Animal; Muscle Co | 2015 |
17β-Aminoestrogens induce guinea pig airway smooth muscle hyperresponsiveness through L-type Ca(2+) channels activation.
Topics: Animals; Calcium Channels, L-Type; Carbachol; Estrogens; Guinea Pigs; Histamine; Male; Muscle Contra | 2015 |
Effects of the aqueous extract of Pittosporum mannii Hook. f. (Pittosporaceae) stem barks on spontaneous and spasmogen-induced contractile activity of isolated rat duodenum.
Topics: Animals; Atropine; Carbachol; Dose-Response Relationship, Drug; Duodenum; Histamine; Histamine Antag | 2015 |
The role of muscarinic receptor subtypes on carbachol-induced contraction of normal human detrusor and overactive detrusor associated with benign prostatic hyperplasia.
Topics: Carbachol; Dose-Response Relationship, Drug; Humans; In Vitro Techniques; Male; Muscarinic Agonists; | 2015 |
Aging changes agonist induced contractile responses in permeabilized rat bladder.
Topics: Aging; Animals; Calcium Signaling; Carbachol; Cholinergic Agonists; Escin; Female; Muscle Contractio | 2015 |
Interleukin-6 (IL-6) mediated the increased contraction of distal colon in streptozotocin-induced diabetes in rats via IL-6 receptor pathway.
Topics: Animals; Carbachol; Colon; Cytokine Receptor gp130; Diabetes Mellitus, Experimental; Diabetes Mellit | 2015 |
On the origin of spontaneous activity in the bladder.
Topics: Adenosine Triphosphate; Animals; Carbachol; Cholinergic Agonists; Dose-Response Relationship, Drug; | 2016 |
Urinary Bladder Dysfunction in Transgenic Sickle Cell Disease Mice.
Topics: Acetanilides; Adenosine Triphosphate; Anemia, Sickle Cell; Animals; Atropine; Calcium Chloride; Carb | 2015 |
Role of Telokin in Regulating Murine Gastric Fundus Smooth Muscle Tension.
Topics: Animals; Carbachol; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Gastric Fundus; Male; Mice; Mi | 2015 |
Acotiamide Hydrochloride, a Therapeutic Agent for Functional Dyspepsia, Enhances Acetylcholine-induced Contraction via Inhibition of Acetylcholinesterase Activity in Circular Muscle Strips of Guinea Pig Stomach.
Topics: Acetylcholine; Acetylcholinesterase; Animals; Benzamides; Benzyl Compounds; Carbachol; Cholinesteras | 2016 |
Flavonoid galetin 3,6-dimethyl ether attenuates guinea pig ileum contraction through K(+) channel activation and decrease in cytosolic calcium concentration.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 2015 |
Differences in time to peak carbachol-induced contractions between circular and longitudinal smooth muscles of mouse ileum.
Topics: Animals; Carbachol; Cholinergic Agonists; Gap Junctions; Ileum; In Vitro Techniques; Male; Mice, Inb | 2016 |
Intensity of swimming exercise influences tracheal reactivity in rats.
Topics: Aminophylline; Animals; Carbachol; In Vitro Techniques; Lipid Peroxidation; Male; Muscle Contraction | 2015 |
Denatonium and 6-n-Propyl-2-thiouracil, Agonists of Bitter Taste Receptor, Inhibit Contraction of Various Types of Smooth Muscles in the Rat and Mouse.
Topics: Animals; Carbachol; Humans; Male; Mice; Mice, Inbred C57BL; Muscle Contraction; Muscle, Smooth; Pota | 2016 |
The role of TRPP2 in agonist-induced gallbladder smooth muscle contraction.
Topics: Animals; Blotting, Western; Calcium; Carbachol; Cholecystokinin; Cholinergic Agonists; Endothelin-1; | 2016 |
RQ-00201894: A motilin receptor agonist causing long-lasting facilitation of human gastric cholinergically-mediated contractions.
Topics: Acetylcholine; Animals; Carbachol; CHO Cells; Cricetulus; Dose-Response Relationship, Drug; Electric | 2016 |
The effect of Flos Lonicerae Japonicae extract on gastro-intestinal motility function.
Topics: Animals; Benzamides; Carbachol; Cats; Cells, Cultured; Domperidone; Dose-Response Relationship, Drug | 2016 |
Physiological signalling to myosin phosphatase targeting subunit-1 phosphorylation in ileal smooth muscle.
Topics: Animals; Carbachol; Electric Stimulation; Ileum; Intracellular Signaling Peptides and Proteins; Male | 2016 |
Heat Shock-Related Protein 20 Peptide Decreases Human Airway Constriction Downstream of β2-Adrenergic Receptor.
Topics: Actins; Adrenergic beta-2 Receptor Antagonists; Allergens; Animals; Bronchial Hyperreactivity; Carba | 2016 |
Carbachol dimers as homobivalent modulators of muscarinic receptors.
Topics: Animals; Binding Sites; Carbachol; CHO Cells; Cricetulus; Dimerization; Guinea Pigs; Humans; Ileum; | 2016 |
Constitutively active PKA regulates neuronal acetylcholine release and contractility of guinea pig urinary bladder smooth muscle.
Topics: Acetylcholine; Animals; Carbachol; Cholinergic Agonists; Cholinesterase Inhibitors; Cyclic AMP-Depen | 2016 |
Effects of Gegen (Puerariae lobatae Radix) water extract on improving detrusor overactivity in spontaneously hypertensive rats.
Topics: Animals; Benzofurans; Carbachol; China; Drugs, Chinese Herbal; Male; Muscle Contraction; Muscle, Smo | 2016 |
The actions of isoprenaline and mirabegron in the isolated whole rat and guinea pig bladder.
Topics: Acetanilides; Animals; Arecoline; Carbachol; Female; Guinea Pigs; In Vitro Techniques; Isoproterenol | 2016 |
Effects of ATP and adenosine on contraction amplitude of rat soleus muscle at different temperatures.
Topics: Adenosine; Adenosine Triphosphate; Analysis of Variance; Animals; Carbachol; Cholinergic Agonists; E | 2017 |
Urothelium muscarinic activation phosphorylates CBS(Ser227) via cGMP/PKG pathway causing human bladder relaxation through H2S production.
Topics: Carbachol; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Cystathionine beta-Synthase; Humans; Hy | 2016 |
In vitro effect of nicorandil on the carbachol-induced contraction of the lower esophageal sphincter of the rat.
Topics: Animals; Carbachol; Diazoxide; Dose-Response Relationship, Drug; Esophageal Sphincter, Lower; Glybur | 2016 |
The effect of doxazosin and sildenafil citrate combination on bladder tissue contractility, alpha adrenergic receptor, and iNOS subtype expression in a male rat model of partially bladder outlet obstruction.
Topics: Adrenergic alpha-1 Receptor Antagonists; Animals; Carbachol; Disease Models, Animal; Doxazosin; Male | 2017 |
Long-term treatment with the beta-3 adrenoceptor agonist, mirabegron ameliorates detrusor overactivity and restores cyclic adenosine monophosphate (cAMP) levels in obese mice.
Topics: Acetanilides; Adrenergic beta-3 Receptor Agonists; Animals; Body Weight; Carbachol; Cyclic AMP; Cycl | 2017 |
3-iodothyronamine (T1AM), a novel antagonist of muscarinic receptors.
Topics: Acetylcholine; Animals; Carbachol; Catalytic Domain; Cricetinae; Humans; Male; Mitogen-Activated Pro | 2016 |
Time- and Dose-Dependent Effects of Desflurane in Sensitized Airways.
Topics: Airway Resistance; Anesthetics, Inhalation; Animals; Carbachol; Cholinergic Agents; Cyclic AMP; Desf | 2017 |
The histopathological and pharmacodynamic effects of intradetrusor decorin injected in a rabbit partial bladder outlet obstruction model.
Topics: Animals; Carbachol; Decorin; Disease Models, Animal; Electric Stimulation; Fibrosis; Injections, Int | 2017 |
Inhibition of prostate efferent neurotransmission by amikacin.
Topics: Adenosine Triphosphate; Aged; Amikacin; Animals; Anti-Bacterial Agents; Autonomic Nervous System; Ca | 2008 |
Essential role of IFNbeta and CD38 in TNFalpha-induced airway smooth muscle hyper-responsiveness.
Topics: ADP-ribosyl Cyclase 1; Animals; Bradykinin; Bronchial Hyperreactivity; Calcium; Carbachol; Cells, Cu | 2008 |
Myosin light chain kinase activation and calcium sensitization in smooth muscle in vivo.
Topics: Amides; Animals; Calcium; Calcium Signaling; Calmodulin; Carbachol; Intracellular Signaling Peptides | 2008 |
Examination of signalling pathways involved in muscarinic responses in bovine ciliary muscle using YM-254890, an inhibitor of the Gq/11 protein.
Topics: Animals; Calcium; Carbachol; Cattle; Cells, Cultured; Ciliary Body; Dose-Response Relationship, Drug | 2008 |
Partial outlet obstruction of the rabbit urinary bladder induces selective protein oxidation.
Topics: Animals; Blotting, Western; Carbachol; Cholinergic Agonists; Cytoskeletal Proteins; Disease Models, | 2008 |
Neurotoxicity of Micrurus altirostris (Uruguayan coral snake) venom and its neutralization by commercial coral snake antivenom and specific antiserum raised in rabbits.
Topics: Acetylcholine; Animals; Antivenins; Calcium; Carbachol; Chickens; Elapid Venoms; Elapidae; Horses; I | 2008 |
Adreno-muscarinic synergy in the bladder trigone: calcium-dependent and -independent mechanisms.
Topics: Amides; Animals; Calcium Signaling; Carbachol; Guinea Pigs; Indoles; Male; Maleimides; Muscle Contra | 2009 |
The loss and progressive recovery of voiding after spinal cord interruption in rats is associated with simultaneous changes in autonomous contractile bladder activity.
Topics: Animals; Carbachol; Disease Models, Animal; Female; In Vitro Techniques; Muscarinic Agonists; Muscle | 2009 |
Calcium extrusion by plasma membrane calcium pump is impaired in caveolin-1 knockout mouse small intestine.
Topics: Animals; Calcium; Carbachol; Cattle; Caveolae; Caveolin 1; Cytosol; Intestine, Small; Male; Membrane | 2008 |
The effects of reactive oxygen species on calcium- and carbachol-induced contractile responses in beta-escin permeabilized rat bladder.
Topics: Animals; Calcium; Calcium-Transporting ATPases; Carbachol; Contractile Proteins; Escin; In Vitro Tec | 2008 |
In vitro effect of amikacin on rat and human detrusor muscle contraction.
Topics: Amikacin; Animals; Anti-Bacterial Agents; Calcium Chloride; Carbachol; Dose-Response Relationship, D | 2008 |
Cysteinyl leucotriene receptor type 1 mediates contraction in human and guinea-pig oesophagus.
Topics: Acetates; Animals; Atropine; Capsaicin; Carbachol; Cholinergic Agonists; Cyclopropanes; Esophagus; G | 2008 |
Estrogen administration attenuates bladder outlet obstruction induced oxidative stress in the female rabbit.
Topics: Adenosine Triphosphate; Animals; Antioxidants; Carbachol; Choline O-Acetyltransferase; Cholinergic A | 2009 |
Comparisons of the responses of anterior and posterior human adult male bladder neck smooth muscle to in vitro stimulation.
Topics: Adult; Carbachol; Electric Stimulation; Humans; Male; Muscle Contraction; Muscle, Smooth; Norepineph | 2008 |
Involvement of the neurokinin-2 receptor in airway smooth muscle stretch-activated contractions assessed in perfused intact bovine bronchial segments.
Topics: Animals; Bronchi; Calcium Channels, L-Type; Capsaicin; Carbachol; Cattle; Female; Gadolinium; In Vit | 2008 |
Signal transduction pathways of muscarinic receptor mediated activation in the newborn and adult mouse urinary bladder.
Topics: Animals; Blotting, Western; Calcium; Carbachol; Enzyme Inhibitors; Female; Gap Junctions; Guanylate | 2009 |
Activation of cholinergic receptors blocks non-adrenergic non-cholinergic contractions in the rat urinary bladder.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 2008 |
Effects of long-term dietary soy treatment on female urethral morphology and function in ovariectomized nonhuman primates.
Topics: Animals; Carbachol; Dietary Proteins; Disease Models, Animal; Female; Immunohistochemistry; Macaca f | 2008 |
Effects of a selection of histone deacetylase inhibitors on mast cell activation and airway and colonic smooth muscle contraction.
Topics: Animals; Benzamides; Carbachol; Cholinergic Agonists; Colon; Guinea Pigs; Histamine; Histamine Agoni | 2008 |
Curcumin reverses attenuated carbachol-induced contraction of the colon in a rat model of colitis.
Topics: Animals; Carbachol; Colitis; Colon; Curcumin; Disease Models, Animal; Male; Muscle Contraction; NF-k | 2009 |
Pharmacological and biological screening of ascorbigen: protection against glucose-induced endothelial cell toxicity.
Topics: Animals; Antioxidants; Antiprotozoal Agents; Aorta; Ascorbic Acid; Biological Products; Carbachol; C | 2008 |
L-carnitine treatment partially restores urinary bladder function of streptozotocin diabetic rats.
Topics: Adenosine; Adenosine Triphosphate; Adrenergic beta-Agonists; Animals; Autonomic Nervous System; Bloo | 2008 |
Prophylactic role of oral L-arginine on histological and contractile changes in a rat chronic bladder injury model.
Topics: Administration, Oral; Adrenergic beta-Agonists; Animals; Arginine; Carbachol; Cholinergic Agonists; | 2008 |
Inhibitory action of hydrogen sulfide on muscarinic receptor-induced contraction of isolated porcine irides.
Topics: Animals; Carbachol; Cystathionine beta-Synthase; Cystathionine gamma-Lyase; Dose-Response Relationsh | 2008 |
Effect of lidocaine on endothelin-1-mediated airway smooth muscle contraction in the rat trachea.
Topics: Anesthetics, Local; Animals; Bronchodilator Agents; Calcium; Calcium Channels; Calcium Signaling; Ca | 2008 |
Effect of low level laser therapy on bronchial hyper-responsiveness.
Topics: Animals; Base Sequence; Bronchial Hyperreactivity; Calcium; Carbachol; DNA Primers; Gene Expression; | 2009 |
Ablation of smooth muscle myosin heavy chain SM2 increases smooth muscle contraction and results in postnatal death in mice.
Topics: Animals; Animals, Newborn; Carbachol; Female; Heterozygote; Male; Mice; Mice, Inbred C57BL; Mice, Kn | 2008 |
A1 and A2a receptors mediate inhibitory effects of adenosine on the motor activity of human colon.
Topics: Adenosine; Carbachol; Cholinergic Agonists; Colon; Electric Stimulation; Gastrointestinal Motility; | 2009 |
In vitro effects of the cyclooxygenase inhibitor indomethacin and of the phospholipase-C inhibitor U-73122 on carbachol-induced contractions of porcine detrusor muscle.
Topics: Animals; Carbachol; Cholinergic Agonists; Cyclooxygenase Inhibitors; Dose-Response Relationship, Dru | 2008 |
Glucose-dependent enhancement of diabetic bladder contraction is associated with a rho kinase-regulated protein kinase C pathway.
Topics: Animals; Blood Glucose; Carbachol; Cholesterol; Diabetes Mellitus, Type 2; Fatty Acids, Nonesterifie | 2009 |
Ovalbumin-induced sensitization affects non-quantal acetylcholine release from motor nerve terminals and alters contractility of skeletal muscles in mice.
Topics: Acetylcholine; Animals; Carbachol; Cholinergic Agonists; Disease Models, Animal; Electrophysiology; | 2009 |
Functional role of cholinergic drugs on spontaneous muscular activity in the amphistome Gastrothylax crumenifer from ruminants.
Topics: Acetylcholine; Animals; Atropine; Carbachol; Cholinergic Agents; Dose-Response Relationship, Drug; G | 2009 |
Inhibitory effect of quercetin on rat trachea contractility in vitro.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Antioxidants; Benzamides; Capsai | 2009 |
Evidence for a modulatory role of orexin A on the nitrergic neurotransmission in the mouse gastric fundus.
Topics: Animals; Benzoxazoles; Carbachol; Cholinergic Agonists; Dimethylphenylpiperazinium Iodide; Electric | 2009 |
Alterations of urine TGF-beta1 and bFGF following bladder outlet obstruction: a predictor for detrusor contractibility?
Topics: Animals; Biomarkers; Carbachol; Cholinergic Agonists; Disease Models, Animal; Female; Fibroblast Gro | 2009 |
Mitogen-activated protein kinase pathways contribute to hypercontractility and increased Ca2+ sensitization in murine experimental colitis.
Topics: Animals; Calcium; Carbachol; Colitis; Colon; Cytokines; Dextran Sulfate; Extracellular Signal-Regula | 2009 |
Expression of RhoA mRNA and activated RhoA in urothelium and smooth muscle, and effects of a Rho-kinase inhibitor on contraction of the porcine urinary bladder.
Topics: Amides; Animals; Blotting, Western; Carbachol; Cholinergic Agonists; Dose-Response Relationship, Dru | 2009 |
Obstruction alters muscarinic receptor-coupled RhoA/Rho-kinase pathway in the urinary bladder of the rat.
Topics: Amides; Animals; Blotting, Western; Carbachol; Electric Stimulation; Electrophoresis, Polyacrylamide | 2009 |
Lubiprostone stimulates secretion from tracheal submucosal glands of sheep, pigs, and humans.
Topics: Alprostadil; Animals; Anions; Carbachol; Chloride Channels; Cystic Fibrosis; Dose-Response Relations | 2009 |
Contribution of RhoA kinase and protein kinase C to weak relaxant effect of pinacidil on carbachol-induced contractions in sensitized guinea-pig trachealis.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine; Animals; Benzophenanthridines; Bronchodila | 2009 |
In vitro and in vivo pharmacological characterization of PF-01354082, a novel partial agonist selective for the 5-HT(4) receptor.
Topics: Administration, Oral; Animals; Benzimidazoles; Carbachol; Cell Line; CHO Cells; Cholinergic Agonists | 2009 |
Phospholipase C mediated Ca2+ signals in murine urinary bladder smooth muscle.
Topics: Animals; Calcium; Calcium Channel Blockers; Carbachol; Cholinergic Agonists; Enzyme Inhibitors; Estr | 2009 |
Modification of rat detrusor muscle contraction by ascorbic acid and citric acid involving enhanced neurotransmitter release and Ca2+ influx.
Topics: Adenosine Triphosphate; Animals; Antioxidants; Ascorbic Acid; Atropine; Calcium Signaling; Carbachol | 2009 |
Potentiation of carbachol-induced detrusor smooth muscle contractions by beta-adrenoceptor activation.
Topics: Animals; Carbachol; Cell Adhesion Molecules; Dose-Response Relationship, Drug; Extracellular Signal- | 2009 |
Relaxant effect of brain natriuretic peptide in nonsensitized and passively sensitized isolated human bronchi.
Topics: Bronchi; Bronchial Hyperreactivity; Carbachol; Histamine; Humans; Immunization, Passive; In Vitro Te | 2009 |
Effects of NO/L-arginine pathway on gallbladder contractility in bile duct ligated guinea pigs.
Topics: Animals; Arginine; Carbachol; Cholecystitis; Common Bile Duct; Electric Stimulation; Gallbladder; Gu | 2009 |
Effects of 17beta-oestradiol on rat detrusor smooth muscle contractility.
Topics: Animals; Calcium; Carbachol; Electric Stimulation; Estradiol; Fulvestrant; In Vitro Techniques; Male | 2009 |
Gastric relaxation induced by apigenin and quercetin: analysis of the mechanism of action.
Topics: Animals; Apigenin; Calcium; Calcium Channel Blockers; Carbachol; Cyclic AMP; Cyclic GMP; In Vitro Te | 2009 |
Effect of pre-contraction on β-adrenoceptor-mediated relaxation of rat urinary bladder.
Topics: Adrenergic beta-Agonists; Animals; Bradykinin; Carbachol; Colforsin; Dose-Response Relationship, Dru | 2009 |
Food allergy alters jejunal circular muscle contractility and induces local inflammatory cytokine expression in a mouse model.
Topics: Animals; Carbachol; Cholinergic Agents; Cytokines; Disease Models, Animal; Female; Food Hypersensiti | 2009 |
Activation of the nitric oxide-cGMP pathway reduces phasic contractions in neonatal rat bladder strips via protein kinase G.
Topics: Animals; Animals, Newborn; Carbachol; Cholinergic Agonists; Cyclic GMP; Cyclic GMP-Dependent Protein | 2009 |
In vitro and in vivo characterization of opioid activities of C-terminal esterified endomorphin-2 analogs.
Topics: Acids, Acyclic; Analgesics, Opioid; Animals; Blood Pressure; Carbachol; Cardiovascular System; Colon | 2009 |
Esophageal and gastric smooth muscle activity after carbon dioxide pneumoperitoneum.
Topics: Abdomen; Animals; Carbachol; Carbon Dioxide; Esophagus; Isoproterenol; Laparotomy; Muscle Contractio | 2010 |
Deletion of TRPC4 and TRPC6 in mice impairs smooth muscle contraction and intestinal motility in vivo.
Topics: Acetylcholine; Animals; Atropine; Calcium Channels, L-Type; Calcium Signaling; Carbachol; Cholinergi | 2009 |
Carbachol induces Ca(2+)-dependent contraction via muscarinic M2 and M3 receptors in rat intestinal subepithelial myofibroblasts.
Topics: Acetylcholine; Animals; Carbachol; Cells, Cultured; Cholinergic Agonists; Colon; Male; Muscle Contra | 2009 |
Effect of four medications associated with gastrointestinal motility on Oddi sphincter in the rabbit.
Topics: Animals; Carbachol; Domperidone; Gastrointestinal Agents; Gastrointestinal Motility; Indoles; Male; | 2009 |
Functional significance of muscarinic receptor expression within the proximal and distal rat vagina.
Topics: Animals; Biopsy; Carbachol; Dose-Response Relationship, Drug; Female; Humans; Inositol Phosphates; M | 2009 |
Importance of neural mechanisms in colonic mucosal and muscular dysfunction in adult rats following neonatal colonic irritation.
Topics: Animals; Animals, Newborn; Carbachol; Chlorides; Cholinergic Agonists; Colforsin; Colon; Colonic Dis | 2010 |
N-Acetylcysteine improves disturbed ileal contractility following partial hepatectomy in rats.
Topics: Acetylcysteine; Animals; Carbachol; Dose-Response Relationship, Drug; Electric Stimulation; Gastroin | 2010 |
Effects of fasudil, a Rho-kinase inhibitor, on contraction of pig bladder tissues with or without urothelium.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Carbachol; Cholinergic Agonists; Dose-Respon | 2009 |
Early effects of carbachol on the morphology of motor endplates of mammalian skeletal muscle fibers.
Topics: Analysis of Variance; Animals; Calcium; Carbachol; Cholinergic Agonists; Mice; Microscopy, Electron, | 2010 |
Possible mechanisms for the effect of protein sensitization on contractile function of fast and slow muscles in mice.
Topics: Aluminum Hydroxide; Animals; Carbachol; Female; Male; Mice; Muscle Contraction; Muscle Fibers, Fast- | 2009 |
Inhaled ammonium persulphate inhibits non-adrenergic, non-cholinergic relaxations in the guinea pig isolated trachea.
Topics: Administration, Inhalation; Ammonium Sulfate; Animals; Carbachol; Carbon Monoxide; Cell Count; Choli | 2010 |
Effects of various selective phosphodiesterase inhibitors on relaxation and cyclic nucleotide contents in porcine iris sphincter.
Topics: Animals; Carbachol; Colforsin; Female; Iris; Male; Muscle Contraction; Nitroprusside; Phosphodiester | 2009 |
Antispasmodic, bronchodilator and blood pressure lowering properties of Hypericum oblongifolium--possible mechanism of action.
Topics: Animals; Aorta; Blood Pressure; Bronchodilator Agents; Calcium Channels; Carbachol; Female; Guinea P | 2010 |
Muscarinic receptor subtypes mediating Ca2+ sensitization of intestinal smooth muscle contraction: studies with receptor knockout mice.
Topics: Animals; Calcium; Carbachol; Female; Guanosine Triphosphate; Ileum; Intestines; Male; Mice; Mice, Kn | 2010 |
Effect of antioxidants on airway smooth muscle contraction: action of lipoic acid and some of its novel derivatives on guinea pig tracheal smooth muscle.
Topics: Animals; Antioxidants; Ascorbic Acid; Benzamides; Carbachol; Drug Synergism; Glutathione; Guinea Pig | 2010 |
Effect of endogenous and synthetic antioxidants on hydrogen peroxide-induced guinea-pig colon contraction.
Topics: Animals; Antioxidants; Benzamides; Carbachol; Colon; GTP-Binding Proteins; Guinea Pigs; Histamine; H | 2010 |
Variations in the pharmacological profile of post-synaptic neurotoxins isolated from the venoms of the Papuan (Oxyuranus scutellatus canni) and coastal (Oxyuranus scutellatus scutellatus) taipans.
Topics: Amino Acid Sequence; Animals; Carbachol; Chickens; Dose-Response Relationship, Drug; Elapid Venoms; | 2010 |
17Beta-estradiol induces gastrointestinal motility disorder by decreasing CPI-17 phosphorylation via changes in rho-family G-protein Rnd expression in small intestine.
Topics: Animals; Carbachol; Dose-Response Relationship, Drug; Estradiol; Female; Gastrointestinal Motility; | 2009 |
Herpes simplex virus type 1 infection of the rat enteric nervous system evokes small-bowel neuromuscular abnormalities.
Topics: Acetylcholine; Animals; Calcium Chloride; Carbachol; CD3 Complex; Disease Models, Animal; Dose-Respo | 2010 |
The effects of chronic hyperlipidemia on bladder function in myocardial infarction-prone Watanabe heritable hyperlipidemic (WHHLMI) rabbits.
Topics: Animals; Atherosclerosis; Calcitonin Gene-Related Peptide; Carbachol; Cholinergic Agonists; Chronic | 2010 |
Comparison of human and porcine gastric clasp and sling fiber contraction by M2 and M3 muscarinic receptors.
Topics: Animals; Benzofurans; Carbachol; Diamines; Dose-Response Relationship, Drug; Esophagogastric Junctio | 2010 |
Effect of human chorionic gonadotrophin on in vitro contractions of stimulated detrusor muscle strips of female rats.
Topics: Adenosine Diphosphate; Analysis of Variance; Animals; Carbachol; Chorionic Gonadotropin; Dose-Respon | 2009 |
Contraction-related stimuli regulate GLUT4 traffic in C2C12-GLUT4myc skeletal muscle cells.
Topics: Acetylcholine; AMP-Activated Protein Kinases; Animals; Blotting, Western; Calcium; Calcium Signaling | 2010 |
Anticholinergic effects of cis- and trans-isomers of two metabolites of propiverine.
Topics: Animals; Benzilates; Calcium; Carbachol; Cholinergic Antagonists; Dose-Response Relationship, Drug; | 2010 |
Effects of bladder outlet obstruction on properties of Ca2+-activated K+ channels in rat bladder.
Topics: Animals; Apamin; Carbachol; Charybdotoxin; Cholinergic Agonists; Female; Large-Conductance Calcium-A | 2010 |
[Modulation of the smooth muscle contractions of the rat vas deferens by TRPM8 channel agonist menthol].
Topics: Animals; Calcium; Calcium-Transporting ATPases; Capsaicin; Carbachol; Cold Temperature; In Vitro Tec | 2009 |
Deletion of microsomal prostaglandin E synthase-1 does not alter ozone-induced airway hyper-responsiveness.
Topics: Airway Resistance; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carbachol; Cell Differentiation | 2010 |
Functional effects of the KCNQ modulators retigabine and XE991 in the rat urinary bladder.
Topics: Animals; Anthracenes; Anticonvulsants; Carbachol; Carbamates; Dose-Response Relationship, Drug; Drug | 2010 |
Voltage-gated K(+) channels sensitive to stromatoxin-1 regulate myogenic and neurogenic contractions of rat urinary bladder smooth muscle.
Topics: Action Potentials; Animals; Carbachol; Electric Stimulation; Female; Male; Membrane Potentials; Musc | 2010 |
FIZZ1 potentiates the carbachol-induced tracheal smooth muscle contraction.
Topics: Animals; Asthma; Bronchoalveolar Lavage Fluid; Carbachol; Cholinergic Agonists; Disease Models, Anim | 2010 |
TPC2 proteins mediate nicotinic acid adenine dinucleotide phosphate (NAADP)- and agonist-evoked contractions of smooth muscle.
Topics: Animals; Calcium; Calcium Channels; Carbachol; Cell Membrane; Dose-Response Relationship, Drug; Gene | 2010 |
Evaluation of urinary bladder function after acute spinal cord injury: an experimental study.
Topics: Animals; Carbachol; Laminectomy; Male; Muscle Contraction; Potassium Chloride; Rabbits; Reference Va | 2010 |
Bronchodilatory effect of Acorus calamus (Linn.) is mediated through multiple pathways.
Topics: Acorus; Animals; Atropine; Bronchodilator Agents; Calcium Channel Blockers; Carbachol; Female; Guine | 2010 |
Gender- and age-related differences in muscular and nerve-mediated responses in human colon.
Topics: Aged; Aged, 80 and over; Aging; Atropine; Carbachol; Colon; Dose-Response Relationship, Drug; Electr | 2011 |
PKCε regulates contraction-stimulated GLUT4 traffic in skeletal muscle cells.
Topics: Adenylate Kinase; Animals; Carbachol; Dose-Response Relationship, Drug; Gene Expression Regulation; | 2011 |
Diabetes mellitus- and cooling-induced bladder contraction: an in vitro study.
Topics: Acetylcholine; Animals; Carbachol; Cold Temperature; Diabetes Mellitus, Experimental; Female; In Vit | 2010 |
Involvement of Src family kinase activation in angiotensin II-induced hyperresponsiveness of rat bronchial smooth muscle.
Topics: Angiotensin II; Animals; Bronchi; Carbachol; Enzyme Activation; Immunoblotting; Indoles; Male; Muscl | 2010 |
Biochemical and functional correlates of an increased membrane density of caveolae in hypertrophic rat urinary bladder.
Topics: Animals; Bradykinin; Carbachol; Caveolae; Caveolin 1; Cell Membrane; Female; Hypertrophy; In Vitro T | 2010 |
The role of the urothelium and ATP in mediating detrusor smooth muscle contractility.
Topics: Adenosine Triphosphate; Animals; Carbachol; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; | 2010 |
On the nature of the interaction between chlorpromazine and the muscarinic receptor.
Topics: Animals; Binding, Competitive; Carbachol; Chlorpromazine; Cholinergic Agonists; Dose-Response Relati | 1981 |
Glial cell line-derived neurotrophic factor protein content in rat skeletal muscle is altered by increased physical activity in vivo and in vitro.
Topics: Animals; Bungarotoxins; Carbachol; Electric Stimulation; Glial Cell Line-Derived Neurotrophic Factor | 2011 |
Biomechanical properties and innervation of the female caveolin-1-deficient detrusor.
Topics: Adenosine Triphosphate; Animals; Base Sequence; Biomechanical Phenomena; Carbachol; Caveolae; Caveol | 2011 |
[Preliminary studies of the mechanism of carbachol increase contraction in rat ventricular myocytes].
Topics: Animals; Calcium Channels, L-Type; Carbachol; Cholinergic Agonists; Heart Ventricles; Muscle Contrac | 2004 |
Effects of the gonadotropin-releasing hormone antagonist ganirelix on normal micturition and prostaglandin E(2)-induced detrusor overactivity in conscious female rats.
Topics: Administration, Intravesical; Animals; Blotting, Western; Carbachol; Cholinergic Agonists; Conscious | 2011 |
Bladder contractility is mediated by different K+ channels in the urothelium and detrusor smooth muscle.
Topics: Animals; Carbachol; Cholinergic Agonists; Dose-Response Relationship, Drug; Drug Evaluation, Preclin | 2011 |
Contribution of Rho-kinase to membrane excitability of murine colonic smooth muscle.
Topics: Amides; Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Carbachol; Cell Membrane; Colon | 2011 |
Characterization of bencycloquidium bromide, a novel muscarinic M(3) receptor antagonist in guinea pig airways.
Topics: Animals; Antigens; Atrial Function, Right; Bridged Bicyclo Compounds, Heterocyclic; Bronchoconstrict | 2011 |
Desensitization of depolarization-mediated contractile pathways does not necessarily regulate receptor-mediated excitation-contraction coupling in longitudinal smooth muscle of guinea pig ileum.
Topics: Animals; Calcium; Calcium Channels; Carbachol; Desensitization, Psychologic; Excitation Contraction | 2011 |
Antibodies interfering with the type 3 muscarinic receptor pathway inhibit gastrointestinal motility and cholinergic neurotransmission in Sjögren's syndrome.
Topics: Acetylcholine; Analysis of Variance; Animals; Antineoplastic Combined Chemotherapy Protocols; Autoan | 2011 |
TRPA1 receptor modulation attenuates bladder overactivity induced by spinal cord injury.
Topics: Acetanilides; Acrolein; Animals; Ankyrins; Calcium Channels; Capsaicin; Carbachol; Disease Models, A | 2011 |
Inhibitory effects of indicaxanthin on mouse ileal contractility: analysis of the mechanism of action.
Topics: Animals; Betaxanthins; Biomechanical Phenomena; Carbachol; Cyclic AMP; Enzyme Inhibitors; Ileum; In | 2011 |
Hydrogen sulphide inhibits carbachol-induced contractile responses in β-escin permeabilized guinea-pig taenia caecum.
Topics: Animals; Caffeine; Calcium; Calcium-Transporting ATPases; Carbachol; Carbonyl Cyanide p-Trifluoromet | 2011 |
Acute colonic inflammation triggers detrusor instability via activation of TRPV1 receptors in a rat model of pelvic organ cross-sensitization.
Topics: Acute Disease; Animals; Carbachol; Cholinergic Agents; Colitis; Diterpenes; Electric Stimulation; Ma | 2011 |
Sildenafil decreases rat tracheal hyperresponsiveness to carbachol and changes canonical transient receptor potential gene expression after antigen challenge.
Topics: Animals; Calcium Channels; Carbachol; Gene Expression; Lactones; Male; Muscle Contraction; Nitric Ox | 2011 |
Presynaptic action of Bothriopsis bilineata smargadina (forest viper) venom in vitro.
Topics: Acetylcholine; Animals; Carbachol; Chickens; Creatine Kinase; Diaphragm; In Vitro Techniques; Membra | 2011 |
Transient receptor potential ankyrin 1 is expressed by inhibitory motoneurons of the mouse intestine.
Topics: Acrolein; Aldehydes; Animals; Carbachol; Cecum; Colon; Duodenum; Epithelial Cells; Female; Fluoresce | 2011 |
Plasticity of non-adrenergic non-cholinergic bladder contractions in rats after chronic spinal cord injury.
Topics: Acetylcholine; Adenosine Triphosphate; Animals; Carbachol; Cholinergic Agonists; Female; Muscarinic | 2011 |
Dietary phytoestrogens maintain contractile responses to carbachol with age in the female rat isolated bladder.
Topics: Age Factors; Animal Feed; Animals; Body Weight; Carbachol; Cholinergic Agonists; Female; Glycine max | 2011 |
Rhos and Rho kinases in the rat prostate: their possible functional roles and distributions.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Carbachol; Immunoblotting; Immunohistochemis | 2011 |
The importance of Rho-associated kinase-induced Ca2+ sensitization as a component of electromechanical and pharmacomechanical coupling in rat ureteric smooth muscle.
Topics: Action Potentials; Animals; Calcium; Calcium Signaling; Carbachol; Enzyme Activation; Kidney; Mechan | 2011 |
Mitochondrial involvement in carbachol-induced intracellular Ca2+ mobilization and contraction in rat gastric smooth muscle.
Topics: Animals; Calcium; Calcium Signaling; Carbachol; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; | 2011 |
Contractions of the mouse prostate elicited by acetylcholine are mediated by M(3) muscarinic receptors.
Topics: Acetylcholine; Adrenergic alpha-1 Receptor Antagonists; Animals; Benzofurans; Body Weight; Carbachol | 2011 |
Large conductance Ca2+ -activated K+ channel activation with NS1619 decreases myogenic and neurogenic contractions of rat detrusor smooth muscle.
Topics: Animals; Benzimidazoles; Carbachol; Choline; Cholinergic Agonists; In Vitro Techniques; Ion Channel | 2011 |
Role of M1 receptor in regulation of gastric fundus smooth muscle contraction.
Topics: Animals; Atropine; Carbachol; Cholinergic Agonists; Dose-Response Relationship, Drug; Gastric Fundus | 2011 |
Effects of cannabinoid agonists on sheep sphincter of oddi in vitro.
Topics: Analgesics; Animals; Arachidonic Acids; Benzoxazines; Camphanes; Cannabinoid Receptor Agonists; Cann | 2011 |
Muscarinic receptor subtypes involved in regulation of colonic motility in mice: functional studies using muscarinic receptor-deficient mice.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Animals; Biomechanical Phenome | 2011 |
Movement based artifacts may contaminate extracellular electrical recordings from GI muscles.
Topics: Androstadienes; Animals; Artifacts; Calcium Channel Blockers; Carbachol; Cholinergic Agonists; Elect | 2011 |
KV2.1 and electrically silent KV channel subunits control excitability and contractility of guinea pig detrusor smooth muscle.
Topics: Animals; Carbachol; Cardiotonic Agents; Female; Guinea Pigs; Humans; Ion Channel Gating; Male; Membr | 2012 |
Urothelial/lamina propria spontaneous activity and the role of M3 muscarinic receptors in mediating rate responses to stretch and carbachol.
Topics: Animals; Atropine; Benzhydryl Compounds; Benzofurans; Carbachol; Cresols; Diamines; Mandelic Acids; | 2011 |
Synchronous phosphorylation of CPI-17 and MYPT1 is essential for inducing Ca(2+) sensitization in intestinal smooth muscle.
Topics: Amides; Animals; Calcium; Carbachol; Carbazoles; Cholinergic Agonists; Guanosine Triphosphate; Intes | 2011 |
Blebbistain, a myosin II inhibitor, as a novel strategy to regulate detrusor contractility in a rat model of partial bladder outlet obstruction.
Topics: Animals; Carbachol; Disease Models, Animal; Gene Expression Regulation; Heterocyclic Compounds, 4 or | 2011 |
Influence of influenza A infection on capsaicin-induced responses in murine airways.
Topics: Animals; Biphenyl Compounds; Bronchoalveolar Lavage Fluid; Capsaicin; Carbachol; Cyclooxygenase Inhi | 2012 |
Hydrogen sulfide (H₂S) and hypoxia inhibit salmonid gastrointestinal motility: evidence for H₂S as an oxygen sensor.
Topics: Anaerobiosis; Animals; Carbachol; Gastrointestinal Motility; Hydrogen Sulfide; Intestines; Muscle Co | 2011 |
The contribution of protein kinase C and CPI-17 signaling pathways to hypercontractility in murine experimental colitis.
Topics: Animals; Carbachol; Cholinergic Agonists; Colitis; Colon; Female; Intracellular Signaling Peptides a | 2012 |
Role of calcium in contractile responses of calf cardiac vein during cooling.
Topics: Animals; Caffeine; Calcium; Carbachol; Cattle; Cold Temperature; Coronary Vessels; Egtazic Acid; In | 2011 |
Screening for anti-inflammatory and bronchorelaxant activities of 12 commonly used Chinese herbal medicines.
Topics: Acetylcholine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Bronchodilator Agents; Carbachol; C | 2012 |
Relaxant and contractile responses of detrusor muscle strips obtained from bladder outlet-obstructed rats treated with doxazosin enantiomers.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic beta-Agonists; Animals; Carbachol; Cholinergic A | 2011 |
Contractile activity of the bladder urothelium/lamina propria and its regulation by nitric oxide.
Topics: Animals; Carbachol; Dose-Response Relationship, Drug; Electric Stimulation; In Vitro Techniques; Muc | 2012 |
The calcium channel blocking and phosphodiesterase inhibitory activities of the extract of Andropogon muricatus explains its medicinal use in airways disorders.
Topics: Andropogon; Animals; Asthma; Calcium Channel Blockers; Calcium Channels; Carbachol; Guinea Pigs; In | 2012 |
In-vitro characterization of the pharmacological effects induced by (-)-α-bisabolol in rat smooth muscle preparations.
Topics: Animals; Carbachol; Cystitis; Disease Models, Animal; Duodenum; Ifosfamide; In Vitro Techniques; Inf | 2012 |
Adjustable passive stiffness in mouse bladder: regulated by Rho kinase and elevated following partial bladder outlet obstruction.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Carbachol; Cholinergic Agonists; Dinoproston | 2012 |
Regional quantification of muscarinic acetylcholine receptors and β-adrenoceptors in human airways.
Topics: Aged; Carbachol; Female; Humans; In Vitro Techniques; Isoproterenol; Ligands; Lung; Male; Middle Age | 2012 |
Effects of imidazolines on neurogenic contraction in isolated urinary bladder detrusor strips from rabbit.
Topics: Adenosine Triphosphate; Agmatine; Animals; Carbachol; Clonidine; Dose-Response Relationship, Drug; E | 2012 |
Two for one: cyclic AMP mediates the anti-inflammatory and anti-spasmodic properties of the non-anesthetic lidocaine analog JMF2-1.
Topics: Adenylyl Cyclases; Animals; Anti-Inflammatory Agents; Apoptosis; Asthma; Carbachol; Caspase 8; Cell | 2012 |
Obstruction enhances rho-kinase pathway and diminishes protein kinase C pathway in carbachol-induced calcium sensitization in contraction of α-toxin permeabilized guinea pig detrusor smooth muscle.
Topics: Amides; Animals; Calcium; Carbachol; Enzyme Inhibitors; Guinea Pigs; Indoles; Male; Maleimides; Musc | 2012 |
Functional role of muscarinic receptor subtypes in calcium sensitization and their contribution to rho-kinase and protein kinase C pathways in contraction of human detrusor smooth muscle.
Topics: Amides; Calcium; Carbachol; Enzyme Inhibitors; Humans; In Vitro Techniques; Indoles; Maleimides; Mus | 2012 |
Ex vivo pharmacology of surgical samples of the uterosacral ligament. Part I: Effects of carbachol and oxytocin on smooth muscle.
Topics: Carbachol; Cholinergic Agonists; Dose-Response Relationship, Drug; Female; Humans; Ligaments; Muscle | 2012 |
Smooth muscle adaptation and recovery of contractility after massive small bowel resection in rats.
Topics: Adaptation, Physiological; Animals; Carbachol; Cholinergic Agonists; Gastrointestinal Contents; Inte | 2012 |
Relaxant effects of Aike Mixture on isolated bladder and prostatic urethral smooth muscle of rabbits.
Topics: Animals; Calcium Chloride; Carbachol; Drugs, Chinese Herbal; Hydroxylamines; In Vitro Techniques; Ma | 2014 |
Carbachol-induced volume adaptation in mouse bladder and length adaptation via rhythmic contraction in rabbit detrusor.
Topics: Analgesics, Non-Narcotic; Animals; Biological Clocks; Carbachol; Dinoprostone; Female; Mice; Muscle | 2012 |
Antispasmodic effect of 4'-methylepigallocatechin on guinea pig ileum.
Topics: Animals; Barium Compounds; Calcium Chloride; Carbachol; Catechin; Chlorides; Guinea Pigs; Histamine; | 2012 |
Functional investigation of β-adrenoceptors in human isolated detrusor focusing on the novel selective β3-adrenoceptor agonist KUC-7322.
Topics: Acetates; Adrenergic beta-3 Receptor Agonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists | 2012 |
Effect of silymarin on bladder overactivity in cyclophosphamide-induced cystitis rat model.
Topics: Animals; Carbachol; Cyclophosphamide; Cystitis; Disease Models, Animal; Female; Muscle Contraction; | 2012 |
Myogenic regional responsiveness to cholinergic and vipergic stimulation in human colon.
Topics: Aged; Aged, 80 and over; Carbachol; Cholinergic Agonists; Colon; Colon, Ascending; Colon, Sigmoid; F | 2012 |
In vitro and in vivo pharmacological characterization of the novel NK₁ receptor selective antagonist Netupitant.
Topics: Analysis of Variance; Animals; Atropine; Calcium Signaling; Carbachol; CHO Cells; Cholinergic Agonis | 2012 |
Effects of neo-adjuvant chemotherapy for oesophago-gastric cancer on neuro-muscular gastric function.
Topics: Acetylcholinesterase; Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Capecita | 2012 |
In vitro measurements of tracheal constriction using mice.
Topics: Animals; Carbachol; Electric Stimulation; In Vitro Techniques; Mice; Muscle Contraction; Trachea; Tr | 2012 |
Pharmacological characterization of α-elapitoxin-Al2a from the venom of the Australian pygmy copperhead (Austrelaps labialis): an atypical long-chain α-neurotoxin with only weak affinity for α7 nicotinic receptors.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Amino Acid Sequence; Animals; Antivenins; Carbachol; Cell L | 2012 |
Muscarinic receptor subtypes involved in urothelium-derived relaxatory effects in the inflamed rat urinary bladder.
Topics: Animals; Carbachol; Cyclophosphamide; Cystitis; Dose-Response Relationship, Drug; Enzyme Inhibitors; | 2012 |
Action of calcium antagonists and agonists on isolated human thoracic arteries used for coronary artery bypass grafting.
Topics: Adult; Aged; Aged, 80 and over; Amlodipine; Benzimidazoles; Calcium Channel Agonists; Calcium Channe | 2012 |
Expression of alternatively spliced variants of Na-Ca-exchanger-1 in experimental colitis: role in reduced colonic contractility.
Topics: Alternative Splicing; Animals; Blotting, Western; Carbachol; Colitis; Colon; Gastrointestinal Motili | 2012 |
Bryophyllum pinnatum inhibits detrusor contractility in porcine bladder strips--a pharmacological study towards a new treatment option of overactive bladder.
Topics: Animals; Carbachol; Cholinergic Agonists; Electric Stimulation; Kalanchoe; Mandelic Acids; Muscarini | 2012 |
The effect of hypercholesterolemia on carbachol-induced contractions of the detrusor smooth muscle in rats: increased role of L-type Ca2+ channels.
Topics: Amides; Animals; Calcium Channels, L-Type; Carbachol; Cholinergic Agonists; Disease Models, Animal; | 2012 |
Role of curcumin in mesenteric ischemia - reperfusion injury in rats.
Topics: Animals; Carbachol; Curcumin; Dose-Response Relationship, Drug; Esophagus; In Vitro Techniques; Male | 2012 |
Gut fibrosis with altered colonic contractility in a mouse model of scleroderma.
Topics: Animals; Carbachol; Cholinergic Agonists; Colon; Colonic Diseases; Female; Fibroblasts; Fibrosis; Ga | 2012 |
Effects of trypsin, thrombin and proteinase-activated receptors on guinea pig common bile duct motility.
Topics: Animals; Carbachol; Common Bile Duct; Dose-Response Relationship, Drug; Gastrointestinal Motility; G | 2012 |
The bitter taste receptor (TAS2R) agonists denatonium and chloroquine display distinct patterns of relaxation of the guinea pig trachea.
Topics: Albuterol; Animals; Bronchodilator Agents; Carbachol; Charybdotoxin; Chloroquine; Cholinergic Agonis | 2012 |
Variations in carbachol- and ATP-induced contractions of the rat detrusor: effects of gender, mucosa and contractile direction.
Topics: Adenosine Triphosphate; Animals; Carbachol; Cholinergic Agonists; Female; Male; Mucous Membrane; Mus | 2012 |
In vitro sensitivity of rat esophagus to agonists in different alkaline mediums.
Topics: Animals; Carbachol; Dose-Response Relationship, Drug; Esophagus; Hydrogen-Ion Concentration; In Vitr | 2012 |
SMB myosin heavy chain knockout enhances tonic contraction and reduces the rate of force generation in ileum and stomach antrum.
Topics: Animals; Carbachol; Cholinergic Agonists; Ileum; Mice; Mice, Knockout; Muscle Contraction; Muscle St | 2013 |
Role of PKC and CaV1.2 in detrusor overactivity in a model of obesity associated with insulin resistance in mice.
Topics: Adiposity; Amlodipine; Animals; Body Weight; Calcium Channel Blockers; Calcium Channels, L-Type; Cal | 2012 |
Effects of St John's wort and its active constituents, hypericin and hyperforin, on isolated rat urinary bladder.
Topics: Animals; Anthracenes; Carbachol; Cell Membrane; Dose-Response Relationship, Drug; Electric Stimulati | 2012 |
SK channel-selective opening by SKA-31 induces hyperpolarization and decreases contractility in human urinary bladder smooth muscle.
Topics: Adult; Aged; Apamin; Benzothiazoles; Carbachol; Electric Stimulation; Female; Humans; Male; Membrane | 2013 |
The novel β3-adrenoceptor agonist mirabegron reduces carbachol-induced contractile activity in detrusor tissue from patients with bladder outflow obstruction with or without detrusor overactivity.
Topics: Acetanilides; Adrenergic beta-3 Receptor Agonists; Adrenergic beta-Agonists; Aged; Aged, 80 and over | 2013 |
Responses of acrylamide-treated rat bladders.
Topics: Acrylamide; Animals; Carbachol; Female; In Vitro Techniques; Male; Muscle Contraction; Potassium Chl | 2013 |
Effects of hydrogen sulphide on motility patterns in the rat colon.
Topics: Animals; Carbachol; Colon; Dose-Response Relationship, Drug; Gastrointestinal Motility; Hydrogen Sul | 2013 |
Involvement of the Tyr kinase/JNK pathway in carbachol-induced bronchial smooth muscle contraction in the rat.
Topics: Animals; Blotting, Western; Bronchi; Carbachol; JNK Mitogen-Activated Protein Kinases; Male; Mitogen | 2013 |
Signaling through myosin light chain kinase in smooth muscles.
Topics: Animals; Aorta; Calmodulin; Carbachol; Electrophoresis, Polyacrylamide Gel; Gene Expression Regulati | 2013 |
Signaling cross-talk between cannabinoid and muscarinic systems actives Rho-kinase and increases the contractile responses of the bovine ciliary muscle.
Topics: Animals; Arachidonic Acids; Cannabinoid Receptor Agonists; Cannabinoid Receptor Antagonists; Carbach | 2013 |
A role for M(2) and M(3) muscarinic receptors in the contraction of rat and human small airways.
Topics: Animals; Carbachol; Cholinergic Agonists; Humans; In Vitro Techniques; Lung; Muscarinic Antagonists; | 2013 |
The early effects of partial outflow obstruction on contractile properties of diabetic and non-diabetic rat bladder.
Topics: Adenosine Triphosphate; Animals; Carbachol; Diabetes Mellitus, Experimental; Electric Stimulation; F | 2002 |
M(3) receptor antagonism by the novel antimuscarinic agent solifenacin in the urinary bladder and salivary gland.
Topics: Animals; Benzofurans; Bradycardia; Calcium; Carbachol; Cells, Cultured; Cytosol; Dose-Response Relat | 2002 |
Dynamics of length-force relations in airway smooth muscle.
Topics: Animals; Carbachol; Cattle; Cholinergic Agonists; Elasticity; In Vitro Techniques; Isometric Contrac | 2002 |
Inhibitory mechanism of BRL37344 on muscarinic receptor-mediated contractions of the rat urinary bladder smooth muscle.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Analysis of Variance; Animals; Binding, Compe | 2002 |
Interaction between muscarinic receptor subtype signal transduction pathways mediating bladder contraction.
Topics: Animals; Carbachol; Cholinergic Agents; Denervation; Female; In Vitro Techniques; Muscarinic Antagon | 2002 |
Decreased endothelial nitric-oxide synthase (eNOS) activity resulting from abnormal interaction between eNOS and its regulatory proteins in hypoxia-induced pulmonary hypertension.
Topics: Animals; Blotting, Western; Body Weight; Calcium; Carbachol; Cell Membrane; Cyclic GMP; Electrophore | 2002 |
Regional differences in bladder enlargement and in vitro contractility after outlet obstruction in the rabbit.
Topics: Adenosine Triphosphate; Animals; Carbachol; Electric Stimulation; Hypertrophy; In Vitro Techniques; | 2002 |
Impact of parainfluenza-3 virus infection on endothelin receptor density and function in guinea pig airways.
Topics: Analysis of Variance; Animals; Binding Sites; Carbachol; Dose-Response Relationship, Drug; Endotheli | 2002 |
L-carnitine does not exert any in vitro relaxant effect in Guinea pig trachea, lung parenchyma and human bronchial tissue.
Topics: Animals; Bronchi; Carbachol; Carnitine; Dose-Response Relationship, Drug; Guinea Pigs; Histamine; Hu | 2002 |
Antibody-mediated gastrointestinal dysmotility in scleroderma.
Topics: Aged; Animals; Autoantibodies; Calcium Channels, L-Type; Carbachol; Cholinergic Agonists; Colon; Fem | 2002 |
Different responses to drugs against overactive bladder in detrusor muscle of pig, guinea pig and mouse.
Topics: Animals; Atropine; Benzhydryl Compounds; Benzilates; Carbachol; Cholinergic Agonists; Cholinergic An | 2002 |
An assay to evaluate the long-term effects of inflammatory mediators on murine airway smooth muscle: evidence that TNFalpha up-regulates 5-HT(2A)-mediated contraction.
Topics: Animals; Atropine; Carbachol; Dose-Response Relationship, Drug; Gene Expression Profiling; Inflammat | 2002 |
RhoA kinase and protein kinase C participate in regulation of rabbit stomach fundus smooth muscle contraction.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adrenergic alpha-Agonists; Amides; Animals; Carbachol | 2002 |
Inhibitory actions of eugenol on rat isolated ileum.
Topics: Animals; Calcium; Carbachol; Dose-Response Relationship, Drug; Eugenol; Extracellular Space; Ileum; | 2002 |
The functional and structural response to distention of the rabbit whole bladder in vitro.
Topics: Adenosine Triphosphate; Animals; Carbachol; Electric Stimulation; In Vitro Techniques; Male; Muscle | 2002 |
In vitro rat bladder function after neonatal estrogenization.
Topics: Adenosine Triphosphate; Adrenergic Agonists; Animals; Animals, Newborn; Carbachol; Catecholamines; C | 2002 |
Functional importance of the actin cytoskeleton in contraction of bovine iris sphincter muscle.
Topics: Actin Cytoskeleton; Animals; Carbachol; Cattle; Cytoskeleton; Dose-Response Relationship, Drug; In V | 2002 |
Spontaneous mechanical activity and evoked responses in isolated gastric preparations from normal and dystrophic (mdx) mice.
Topics: Anesthetics, Local; Animals; Carbachol; Cholinergic Agonists; Electric Stimulation; Enzyme Inhibitor | 2002 |
Effect of the Bowman-Birk inhibitor (a soy protein) on in vitro bladder neck/urethral and penile corporal smooth muscle activity.
Topics: Adrenergic alpha-Agonists; Animals; Carbachol; Cholinergic Agonists; Dose-Response Relationship, Dru | 2003 |
Role of the T-type Ca2+ current on the contractile performance of guinea pig detrusor smooth muscle.
Topics: Animals; Calcium Channel Blockers; Calcium Channels, T-Type; Carbachol; Cholinergic Agonists; Electr | 2003 |
Mice lacking M2 and M3 muscarinic acetylcholine receptors are devoid of cholinergic smooth muscle contractions but still viable.
Topics: Animals; Carbachol; Digestive System; Electric Stimulation; Female; Gene Targeting; Male; Mice; Mice | 2002 |
Age-related changes in urethrovesical coordination in male rats: relationship with bladder instability?
Topics: Adrenergic Agents; Aging; Animals; Carbachol; Male; Muscle Contraction; Muscle, Smooth; Phenylephrin | 2003 |
Regional and muscle layer variations in cholinergic nerve control of the rat myometrium during the oestrous cycle.
Topics: Animals; Carbachol; Cervix Uteri; Cholinergic Fibers; Dose-Response Relationship, Drug; Electric Sti | 2003 |
Cholinergic regulation of pericyte-containing retinal microvessels.
Topics: Acetylcholine; Animals; Calcium; Capillaries; Carbachol; Electric Stimulation; Fluorescent Dyes; Fur | 2003 |
Focal hypoxia of the obstructed rabbit bladder wall correlates with intermediate decompensation.
Topics: Adenosine Triphosphate; Animals; Calcium-Transporting ATPases; Carbachol; Cholinergic Agonists; Hypo | 2003 |
Mechanisms of reactivity of urinary bladder smooth muscle.
Topics: Acetylcholine; Animals; Carbachol; Cholinergic Agents; Dose-Response Relationship, Drug; Guinea Pigs | 2002 |
Warming and response to contractile agents in calf cardiac vein: role of the nitric oxide.
Topics: Animals; Calcium Chloride; Carbachol; Cattle; Coronary Vessels; Dose-Response Relationship, Drug; En | 2003 |
New benzimidazole derivatives: selective and orally active 5-HT3 receptor antagonists.
Topics: 5-Hydroxytryptophan; Administration, Oral; Animals; Aza Compounds; Behavior, Animal; Benzimidazoles; | 2003 |
Melatonin treatment protects against ischemia/reperfusion-induced functional and biochemical changes in rat urinary bladder.
Topics: Animals; Antioxidants; Carbachol; Cholinergic Agonists; Glutathione; Lipid Peroxidation; Male; Malon | 2003 |
Cholinergic innervation to the upper esophageal sphincter muscle in the eel, with special reference to drinking behavior.
Topics: Acetylcholine; Animals; Carbachol; Cholinergic Agonists; Cholinergic Antagonists; Curare; Deglutitio | 2003 |
Five subtypes of muscarinic receptors are expressed in gastric smooth muscles of guinea pig.
Topics: Animals; Base Sequence; Carbachol; Cations; Cholinergic Agonists; Dose-Response Relationship, Drug; | 2003 |
Droperidol attenuates contractile and phosphatidylinositol responses of rat trachea.
Topics: Adjuvants, Anesthesia; Animals; Antiemetics; Carbachol; Cholinergic Agents; Dose-Response Relationsh | 2003 |
Involvement of Rho/Rho-kinase signalling in the contractile activity and acetylcholine release in the mouse gastric fundus.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Acetylcholine; Amides; Animals; Carbachol; Electric S | 2003 |
Increased connexin43-mediated intercellular communication in a rat model of bladder overactivity in vivo.
Topics: Animals; Carbachol; Cell Communication; Connexin 43; Disease Models, Animal; Female; Gap Junctions; | 2003 |
Functional muscarinic cholinoceptors in the isolated canine ureter.
Topics: Animals; Carbachol; Cholinergic Agonists; Dogs; Dose-Response Relationship, Drug; In Vitro Technique | 2003 |
The evaluation of the effects of renal failure on erectile dysfunction in a rabbit model of chronic renal failure.
Topics: Adrenergic Antagonists; Animals; Carbachol; Dose-Response Relationship, Drug; Endothelium, Vascular; | 2003 |
Agonist- and nerve-induced phasic activity in the isolated whole bladder of the guinea pig: evidence for two types of bladder activity.
Topics: Anesthetics, Local; Animals; Arecoline; Atropine; Carbachol; Cholinergic Agonists; Electric Stimulat | 2003 |
TNF-[alpha] modulates murine tracheal rings responsiveness to G-protein-coupled receptor agonists and KCl.
Topics: Animals; Antigens, CD; Carbachol; Cholera Toxin; Colforsin; Dinoprostone; Drug Synergism; Female; In | 2003 |
Effect of pharmacologically induced smooth muscle activation on permeability in murine colitis.
Topics: Albuterol; Animals; Biguanides; Carbachol; Colitis; Dextran Sulfate; Disease Models, Animal; Female; | 2003 |
Developmental changes in spontaneous smooth muscle activity in the neonatal rat urinary bladder.
Topics: Anesthetics, Local; Animals; Animals, Newborn; Atropine; Carbachol; Cholinergic Agonists; Cholinergi | 2003 |
Hypertrophy changes the muscarinic receptor subtype mediating bladder contraction from M3 toward M2.
Topics: Animals; Carbachol; Cholinergic Agonists; Denervation; Female; Hypertrophy; Muscle Contraction; Rats | 2003 |
Receptor signaling mechanisms underlying muscarinic agonist-evoked contraction in guinea-pig ileal longitudinal smooth muscle.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Animals; Calcium; Carbachol; G | 2003 |
Effects of acid-induced esophagitis on esophageal smooth muscle.
Topics: Animals; Carbachol; Cell Separation; Esophagitis, Peptic; Esophagus; Hydrochloric Acid; Hypertrophy; | 2003 |
Streptozotocin-induced diabetes modulates presynaptic and postsynaptic function in the rat ileum.
Topics: Animals; Calcimycin; Carbachol; Diabetes Mellitus, Experimental; Dinoprost; Dose-Response Relationsh | 2003 |
A quantitative analysis of mRNA expression of alpha 1 and beta-adrenoceptor subtypes and their functional roles in human normal and obstructed bladders.
Topics: Adrenergic Agonists; Aged; Carbachol; Humans; In Vitro Techniques; Male; Middle Aged; Muscle Contrac | 2003 |
Interleukins 1 beta and 6 induce functional alteration of rat colonic motility: an in vitro study.
Topics: Animals; Carbachol; Cholinergic Agents; Colon; Electrophysiology; Gastrointestinal Motility; Interle | 2003 |
Inhibition of smooth muscle contraction by magnolol and honokiol in porcine trachea.
Topics: Animals; Asthma; Biphenyl Compounds; Bronchodilator Agents; Calcium; Carbachol; Dose-Response Relati | 2003 |
Contractility and phenotype of human bronchiole smooth muscle after prolonged fetal bovine serum exposure.
Topics: Adult; Aged; Antibodies, Monoclonal; Blotting, Western; Bronchi; Carbachol; Contractile Proteins; Cu | 2003 |
Thymoquinone-induced relaxation of guinea-pig isolated trachea.
Topics: Animals; Benzoquinones; Carbachol; Dose-Response Relationship, Drug; Guinea Pigs; Male; Muscle Contr | 2001 |
Age-related smooth muscle reactivity changes in the rat bladder: an in vitro study.
Topics: Adenosine Triphosphate; Aging; Animals; Carbachol; Dose-Response Relationship, Drug; In Vitro Techni | 2003 |
Receptor-independent activation of Rho-kinase-mediated calcium sensitisation in smooth muscle.
Topics: Amides; Anal Canal; Animals; Blotting, Western; Calcium; Carbachol; Cell Membrane; Cytosol; Dose-Res | 2003 |
Reactivity of tracheal smooth muscles in albino rats with experimental diabetes mellitus treated with a new complex compound of oxovanadium (IV) and isonicotinic acid hydrazide.
Topics: Alloxan; Animals; Carbachol; Cholinergic Agonists; Diabetes Mellitus, Experimental; Drug Combination | 2003 |
Development changes esophageal smooth muscle reactivity: an in vitro study.
Topics: Adrenergic beta-Agonists; Animals; Animals, Newborn; Carbachol; Dose-Response Relationship, Drug; Es | 2003 |
INFLUENCE OF DRUGS ON 47-CA-2+ RELEASE FROM DEPOLARIZED INTESTINAL SMOOTH MUSCLE.
Topics: Acetylcholine; Animals; Calcium; Carbachol; Creatine; Creatinine; Epinephrine; Guinea Pigs; Histamin | 1964 |
NON-SPECIFIC EFFECTS OF THE TROPOLONES.
Topics: Animals; Arteries; Barium; Carbachol; Chelating Agents; Copper; Edetic Acid; Enzyme Inhibitors; Epin | 1964 |
Enhanced noradrenergic transmission in the spontaneously hypertensive rat anococcygeus muscle.
Topics: Animals; Blotting, Western; Carbachol; Desipramine; Dose-Response Relationship, Drug; Electric Stimu | 2003 |
PDE4D plays a critical role in the control of airway smooth muscle contraction.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Arginine Vasopressin; Bronchoconstrictor Agents; Carba | 2003 |
Pharmacological characterization of the presynaptic activity of Tityus serrulatus venom in the rat anococcygeus muscle.
Topics: Adrenergic alpha-Antagonists; Animals; Atropine; Carbachol; Cholinergic Antagonists; Electric Stimul | 2003 |
Inhibition of human detrusor contraction by a urothelium derived factor.
Topics: Aged; Carbachol; Culture Techniques; Dose-Response Relationship, Drug; Electric Stimulation; Female; | 2003 |
Inhibitory effects of potassium channel blockers on carbachol-induced contraction in rat detrusor muscle.
Topics: 4-Aminopyridine; Animals; Calcium; Calcium Channel Blockers; Carbachol; Dose-Response Relationship, | 2003 |
G protein-coupled receptor kinase 5 regulates airway responses induced by muscarinic receptor activation.
Topics: Animals; Bronchodilator Agents; Carbachol; Cholinergic Agonists; Electric Stimulation; G-Protein-Cou | 2004 |
Preconditioning protects the guinea-pig urinary bladder against ischaemic conditions in vitro.
Topics: Animals; Carbachol; Electric Stimulation; Female; Guinea Pigs; In Vitro Techniques; Inositol 1,4,5-T | 2003 |
IL-13 enhances agonist-evoked calcium signals and contractile responses in airway smooth muscle.
Topics: Animals; Bradykinin; Calcium; Calcium Signaling; Carbachol; Cells, Cultured; Cytosol; Dose-Response | 2003 |
Pharmacological effects of darifenacin on human isolated urinary bladder.
Topics: Aged; Benzofurans; Carbachol; Electric Stimulation; Female; Humans; Male; Muscarinic Antagonists; Mu | 2003 |
Cholinergic transmission to colonic circular muscle of children with slow-transit constipation is unimpaired, but transmission via NK2 receptors is lacking.
Topics: Adolescent; Aged; Aged, 80 and over; Carbachol; Child; Cholinergic Fibers; Colon; Constipation; Huma | 2003 |
Correlation between spontaneous electrical, calcium and mechanical activity in detrusor smooth muscle of the guinea-pig bladder.
Topics: Action Potentials; Amides; Animals; Apamin; Boron Compounds; Calcium; Calcium Signaling; Carbachol; | 2004 |
Melatonin treatment protects against sepsis-induced functional and biochemical changes in rat ileum and urinary bladder.
Topics: Analysis of Variance; Animals; Antioxidants; Carbachol; Glutathione; Ileum; Lipid Peroxidation; Malo | 2004 |
Impaired gastric motility in the gastroesophageal reflux rat model: an in vitro study.
Topics: Animals; Carbachol; Cholinergic Agonists; Disease Models, Animal; Gastric Emptying; Gastric Fundus; | 2003 |
Mast cell stabilization, lipoxygenase inhibition, hyaluronidase inhibition, antihistaminic and antispasmodic activities of Aller-7, a novel botanical formulation for allergic rhinitis.
Topics: Animals; Barium Compounds; Carbachol; Cetirizine; Chlorides; Dose-Response Relationship, Drug; Drug | 2003 |
Effects of prostaglandin F2alpha, latanoprost and carbachol on phosphoinositide turnover, MAP kinases, myosin light chain phosphorylation and contraction and functional existence and expression of FP receptors in bovine iris sphincter.
Topics: Animals; Antihypertensive Agents; Carbachol; Cattle; Culture Techniques; Dinoprost; Dose-Response Re | 2004 |
Capacitative calcium entry in guinea pig gallbladder smooth muscle in vitro.
Topics: Animals; Calcium; Calcium Channel Blockers; Calcium Channels; Carbachol; Cholinergic Agonists; Enzym | 2004 |
Altered contractile responsiveness in ileal longitudinal muscle after total gastrectomy in a rat model.
Topics: Animals; Carbachol; Gastrectomy; Ileum; Ilium; Male; Muscle Contraction; Muscle, Smooth; Postgastrec | 2004 |
Extracts from Rhois aromatica and Solidaginis virgaurea inhibit rat and human bladder contraction.
Topics: Animals; Carbachol; Dose-Response Relationship, Drug; Female; Humans; In Vitro Techniques; Male; Mus | 2004 |
Effect of endotoxins on contractility of smooth muscle preparations from the bovine abomasal antrum.
Topics: Abomasum; Animals; Area Under Curve; Carbachol; Cattle; Cholinergic Agonists; Dose-Response Relation | 2004 |
Hydrogen sulfide as an endogenous regulator of vascular smooth muscle tone in trout.
Topics: Animals; Brachial Artery; Calcium; Calcium Channels, L-Type; Carbachol; Colorimetry; Cyclic GMP; Cyc | 2004 |
Cultured gastrointestinal smooth muscle cells: cell response to contractile agonists depends on their phenotypic state.
Topics: Animals; Carbachol; Cell Differentiation; Cell Proliferation; Cells, Cultured; Extracellular Signal- | 2004 |
Antibodies raised against the second extracellular loop of the human muscarinic M3 receptor mimic functional autoantibodies in Sjögren's syndrome.
Topics: Amino Acid Sequence; Animals; Antibody Specificity; Autoantibodies; Carbachol; Colon; Humans; In Vit | 2004 |
Direct inhibition of rat detrusor muscle contraction by erythromycin.
Topics: Adenosine Triphosphate; Animals; Anti-Bacterial Agents; Atropine; Calcium Channel Blockers; Calcium | 2004 |
Regulation of smooth muscle contraction by calcium, monomeric GTPases of the Rho subfamily and their effector kinases.
Topics: Animals; Calcium; Carbachol; Chelating Agents; Diazonium Compounds; Female; Guinea Pigs; Light; Male | 2003 |
Foregut smooth muscle reactivity changes in the hydrocephalus-induced infantile rats.
Topics: Age Factors; Animals; Carbachol; Cholinergic Agonists; Esophagus; Female; Gastroesophageal Reflux; H | 2004 |
Metoclopramide causes airway smooth muscle relaxation through inhibition of muscarinic M3 receptor in the rat trachea.
Topics: Animals; Antiemetics; Carbachol; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Male; Metoclopra | 2004 |
Persistent and selective effects of inflammation on smooth muscle cell contractility in rat colitis.
Topics: Animals; Carbachol; Cells, Cultured; Cholinergic Agonists; Colitis; Dose-Response Relationship, Drug | 2004 |
8-Bromo-cAMP decreases the Ca2+ sensitivity of airway smooth muscle contraction through a mechanism distinct from inhibition of Rho-kinase.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Bronchi; Calcium; Carbachol; Guanosine 5'-O-(3-Thio | 2004 |
An essential role of Cav1.2 L-type calcium channel for urinary bladder function.
Topics: Amides; Animals; Calcium; Calcium Channels, L-Type; Carbachol; Enzyme Inhibitors; Estrenes; Intracel | 2004 |
Cyclical elongation regulates contractile responses of isolated airways.
Topics: Animals; Bronchi; Bronchoconstriction; Bronchoconstrictor Agents; Carbachol; Electric Stimulation; F | 2004 |
[Carbachol effect on kinetics of the alpha1-adrenergic contractile response of the rat vas deferens].
Topics: Adrenergic alpha-1 Receptor Agonists; Animals; Carbachol; In Vitro Techniques; Kinetics; Male; Musca | 2004 |
Mechanisms involved in carbachol-induced Ca(2+) sensitization of contractile elements in rat proximal and distal colon.
Topics: ADP Ribose Transferases; Alkaloids; Amides; Animals; Bacterial Toxins; Benzophenanthridines; Botulin | 2004 |
Dendroaspis natriuretic peptide system and its paracrine function in rat colon.
Topics: Animals; Carbachol; Cardiotonic Agents; Cell Movement; Chromatography, High Pressure Liquid; Colon; | 2004 |
Involvement of increased arginase activity in impaired cavernous relaxation with aging in the rabbit.
Topics: Aging; Animals; Arginase; Arginine; Carbachol; Cholinergic Agonists; Endothelium, Vascular; Male; Mu | 2004 |
Influence of relaxin on the neurally induced relaxant responses of the mouse gastric fundus.
Topics: Adrenergic Agents; Analysis of Variance; Animals; Carbachol; Cholinergic Agonists; Electric Stimulat | 2004 |
Oral Kohki Tea and its protective effect against in vitro ischemic damage to the bladder.
Topics: Administration, Oral; Animals; Carbachol; Electric Stimulation; Hypoxia; Ischemia; Male; Muscle Cont | 2004 |
Nicotinic receptor inhibition by Tetraponera ant alkaloids.
Topics: Alkaloids; Animals; Ants; Anura; Binding Sites; Binding, Competitive; Brain; Carbachol; Cells, Cultu | 2004 |
Effect of peritonitis on gallbladder smooth muscle contractility in guinea pigs.
Topics: Animals; Carbachol; Cecum; Cholinergic Agonists; Cyclooxygenase Inhibitors; Gallbladder; Guinea Pigs | 2004 |
Characterization of the control of intracellular [Ca2+] and the contractile phenotype of cultured human detrusor smooth muscle cells.
Topics: Calcium; Carbachol; Cells, Cultured; Cholinergic Agonists; Humans; Muscle Contraction; Muscle, Smoot | 2004 |
A sheer pharmacologic approach to compare the contractile effects of PGF2alpha, DL-cloprostenol and D-cloprostenol on isolated uterine, tracheal, ileal and arterial smooth muscle preparations.
Topics: Animals; Arteries; Carbachol; Cloprostenol; Dinoprost; Female; Guinea Pigs; Horses; Ileum; Muscle Co | 2004 |
Cholinergic receptor-mediated differential cytoskeletal recruitment of actin- and integrin-binding proteins in intact airway smooth muscle.
Topics: Actinin; Animals; Blotting, Western; Carbachol; Carrier Proteins; Cattle; Cell Membrane; Cytoskeleto | 2004 |
Parameters of drug antagonism: re-examination of two modes of functional competitive drug antagonism on intraocular muscles.
Topics: Abdominal Muscles; Animals; Atropine; Carbachol; Cholinergic Agonists; Cholinesterase Inhibitors; Do | 2004 |
Sinusoidal length oscillation- and receptor-mediated mRNA expression of myosin isoforms and alpha-SM actin in airway smooth muscle.
Topics: Actins; Animals; Butadienes; Carbachol; Cattle; Cholinergic Agonists; Enzyme Inhibitors; Gene Expres | 2004 |
Effect of timing of diuresis on response of rat bladder to outlet obstruction.
Topics: Animals; Carbachol; Diuresis; Drinking; Electric Stimulation; Male; Muscle Contraction; Muscle, Smoo | 2004 |
Expression of Rho-kinase (ROCK-1 and ROCK-2) and its substantial role in the contractile activity of the sheep ureter.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amides; Animals; Aorta; Atropine; Blotting, Western; | 2004 |
Electroacupuncture ameliorates experimental colitis induced by acetic acid in rat.
Topics: Acetic Acid; Adrenergic beta-Antagonists; Animals; Carbachol; Cholinergic Agonists; Colitis; Electro | 2004 |
Cholelithiatic human gallbladders in vitro fail to respond to cholecystokinin but are responsive to carbachol, histamine, or electrical stimulation.
Topics: Atropine; Carbachol; Cholecystokinin; Cholecystolithiasis; Cholinergic Agonists; Electric Stimulatio | 2004 |
Effects of various selective phosphodiesterase inhibitors on carbachol-induced contraction and cyclic nucleotide contents in guinea pig taenia coli.
Topics: Adenine; Animals; Carbachol; Colforsin; Colon; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, D | 2004 |
IRAG is essential for relaxation of receptor-triggered smooth muscle contraction by cGMP kinase.
Topics: Animals; Aorta; Calcium; Carbachol; Chlorocebus aethiops; Cholinergic Agonists; Colon; COS Cells; Cy | 2004 |
Electroporation-mediated muscarinic M3 receptor gene transfer into rat urinary bladder.
Topics: Animals; Carbachol; Cholinergic Agonists; Electric Stimulation; Electroporation; Feasibility Studies | 2004 |
Reactivity of urinary bladder smooth muscle in guinea pigs to acetylcholine and carbachol--participation of acetylcholinesterase.
Topics: Acetylcholine; Acetylcholinesterase; Animals; Carbachol; Cholinesterase Inhibitors; Guinea Pigs; In | 2005 |
Effect of periurethral denervation on smooth muscles of the lower urinary tract.
Topics: Animals; Biopsy, Needle; Carbachol; Disease Models, Animal; Female; Immunohistochemistry; Muscle Con | 2004 |
Na+-K+ pump stimulation restores carbacholine-induced loss of excitability and contractility in rat skeletal muscle.
Topics: Animals; Carbachol; Cholinergic Agonists; In Vitro Techniques; Membrane Potentials; Muscle Contracti | 2005 |
Bimatoprost and prostaglandin F(2 alpha) selectively stimulate intracellular calcium signaling in different cat iris sphincter cells.
Topics: Amides; Animals; Bimatoprost; Calcium; Calcium Signaling; Carbachol; Cats; Cells, Cultured; Choliner | 2005 |
Preservative solution for freeze-storage of surgically excised human colon to enable study of smooth muscle function in vitro.
Topics: Aged; Buffers; Carbachol; Cholinergic Agonists; Colon; Cryopreservation; Female; Humans; In Vitro Te | 2004 |
Varicose disease affects the P2 receptor-mediated responses of human greater saphenous vein.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Adult; Animals; Arteriosclerosis Obliterans; Carbacho | 2004 |
An evaluation of laparoscopic tissue harvesting for human adult urological smooth muscle physiological experimentation.
Topics: Adult; Carbachol; Cholinergic Agonists; Human Experimentation; Humans; Isotonic Solutions; Laparosco | 2005 |
Endothelin receptors in lower esophageal sphincter circular smooth muscle.
Topics: Animals; Antihypertensive Agents; Carbachol; Cholinergic Agonists; Endothelin Receptor Antagonists; | 2005 |
Contribution of ROCK in contraction of trabecular meshwork: proposed mechanism for regulating aqueous outflow in monkey and human eyes.
Topics: Aged; Aged, 80 and over; Aging; Animals; Aqueous Humor; Carbachol; Ciliary Body; DNA Primers; Eye; H | 2005 |
Antimuscarinic agents exhibit local inhibitory effects on muscarinic receptors in bladder-afferent pathways.
Topics: Acetylcholine; Administration, Intravesical; Afferent Pathways; Animals; Atropine; Benzhydryl Compou | 2005 |
Short-term effects of arsenic sulfur in deficits of contractile and relaxant responses on urinary bladder: pharmacological and structural changes.
Topics: Adenosine Triphosphate; Animals; Arsenicals; Carbachol; Cholinergic Agonists; Electric Stimulation; | 2005 |
Indomethacin-induced ileitis is associated with tensiometric, vascular and oxidative changes in the experimental rat model.
Topics: Acetylcholine; Adrenergic alpha-Agonists; Animals; Carbachol; Cholinergic Agonists; Disease Models, | 2005 |
Activation of the rostral pontine reticular formation increases the spinal glycine level and inhibits bladder contraction in rats.
Topics: Animals; Benzilates; Carbachol; Flavoxate; Glycine; Muscle Contraction; Rats; Rats, Sprague-Dawley; | 2005 |
Inhibition of carbachol-evoked oscillatory currents by the NO donor sodium nitroprusside in guinea-pig ileal myocytes.
Topics: Animals; Caffeine; Carbachol; Chelating Agents; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Eg | 2005 |
Pharmacological profiles of an anticholinergic agent, phencynonate hydrochloride, and its optical isomers.
Topics: Animals; Aza Compounds; Binding, Competitive; Carbachol; Cerebral Cortex; Cholinergic Antagonists; F | 2005 |
Negative feedback regulation of nerve-mediated contractions by KCa channels in mouse urinary bladder smooth muscle.
Topics: Animals; Apamin; Calcium Channel Blockers; Calcium Channels, L-Type; Carbachol; Diltiazem; Drug Syne | 2005 |
Pharmacodynamics of propiverine and three of its main metabolites on detrusor contraction.
Topics: Aged; Aged, 80 and over; Animals; Atropine; Benzilates; Biotransformation; Calcium Channels, L-Type; | 2005 |
Effect of ethanol on the response of the rat urinary bladder to in vitro ischemia: protective effect of alpha-lipoic acid.
Topics: Animals; Carbachol; Ethanol; In Vitro Techniques; Ischemia; Male; Muscle Contraction; Protective Age | 2005 |
Ryanodine receptors in muscarinic receptor-mediated bronchoconstriction.
Topics: Animals; Brain; Bronchi; Calcium; Carbachol; Cell Membrane; Cell Nucleus; Cholinergic Agonists; Dant | 2005 |
Effect of the ATP-sensitive potassium channel opener ZM226600 on cystometric parameters in rats with ligature-intact, partial urethral obstruction.
Topics: Adenosine Triphosphate; Amides; Animals; Benzophenones; Blood Pressure; Carbachol; Dose-Response Rel | 2005 |
Multiple-signaling pathways are involved in the inhibitory effects of galangin on urinary bladder contractility.
Topics: Animals; Calcium Channel Blockers; Calcium Signaling; Carbachol; Depression, Chemical; Electric Stim | 2005 |
Neuronal nitric oxide synthase activity in rat urinary bladder detrusor: participation in M3 and M4 muscarinic receptor function.
Topics: Animals; Carbachol; Cholinergic Agonists; Cyclic GMP; Dose-Response Relationship, Drug; In Vitro Tec | 2005 |
Effects of cyclohexenonic long-chain fatty alcohol on diabetic rat trachea.
Topics: Animals; Blood Glucose; Body Weight; Bronchial Hyperreactivity; Carbachol; Diabetes Mellitus, Experi | 2005 |
M(2) and M(3) muscarinic receptor-mediated contractions in longitudinal smooth muscle of the ileum studied with receptor knockout mice.
Topics: Animals; Calcium Channel Blockers; Carbachol; Cholinergic Agonists; Diamines; Female; Ileum; In Vitr | 2005 |
Involvement of Ca2+ signaling in tachykinin-mediated contractile responses in swine trachea.
Topics: Animals; Calcium; Calcium Channels; Calcium Signaling; Carbachol; Cytosol; Dose-Response Relationshi | 2005 |
Effects of platelet-activating factor on nitrergic transmission in rabbit corpus cavernosum.
Topics: Animals; Carbachol; Cholinergic Agonists; Electric Stimulation; In Vitro Techniques; Male; Muscle Co | 2005 |
Inhibitory mechanism of papaverine on carbachol-induced contraction in bovine trachea.
Topics: Adenosine Triphosphate; Animals; Calcium; Carbachol; Cattle; Cyclic AMP; Cyclic GMP; Female; In Vitr | 2005 |
Effect of phorbol 12,13-dibutyrate on smooth muscle tone in rat stomach fundus.
Topics: Animals; Calcium Chloride; Carbachol; Dose-Response Relationship, Drug; Endothelin-1; Gastric Fundus | 2005 |
Mechanisms underlying the maintenance of muscle hypercontractility in a model of postinfective gut dysfunction.
Topics: Acute Disease; Animals; Carbachol; Cells, Cultured; Cholinergic Agonists; Chronic Disease; Cyclooxyg | 2005 |
DPI-221 [4-((alpha-s)-alpha-((2s,5r)-2,5-dimethyl-4-(3-fluorobenzyl)-1-piperazinyl)benzyl)-N,N-diethylbenzamide]: a novel nonpeptide delta receptor agonist producing increased micturition interval in normal rats.
Topics: Animals; Benzhydryl Compounds; Blood Gas Analysis; Carbachol; Convulsants; Dose-Response Relationshi | 2005 |
Effect of urothelium on bladder contractility in diabetic rats.
Topics: Animals; Carbachol; Diabetes Mellitus, Experimental; Electric Stimulation; Male; Muscarinic Agonists | 2005 |
Effects of ageing on muscarinic receptor subtypes and function in rat urinary bladder.
Topics: Aging; Animals; Atropine; Benzofurans; Carbachol; Cholinergic Agonists; Cholinergic Antagonists; Dos | 2005 |
Effects of various selective phosphodiesterase inhibitors on carbachol-induced contraction and cyclic nucleotide contents in the guinea pig gall bladder.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenine; Animals; Carbachol; Cyclic AMP; Cyclic GMP; | 2005 |
Structure-activity relationships of novel P2-receptor antagonists structurally related to Reactive Blue 2.
Topics: Animals; Anthracenes; Carbachol; Drug Evaluation, Preclinical; Guinea Pigs; Hydrogen Bonding; Male; | 2005 |
Neural regulation of slow-wave frequency in the murine gastric antrum.
Topics: Acetylcholine; Androstenes; Animals; Atropine; Benzamides; Benzimidazoles; Carbachol; Electric Stimu | 2006 |
Pharmacokinetic and pharmacodynamic evaluations of the zwitterionic metabolite of a new series of N-substituted soft anticholinergics.
Topics: Administration, Topical; Animals; Bradycardia; Carbachol; Chemical Phenomena; Chemistry, Physical; C | 2005 |
Comparative study on pharmacological effects of DM-phencynonate hydrochloride and its optical isomers.
Topics: Animals; Aza Compounds; Binding, Competitive; Carbachol; Cerebral Cortex; Female; Glycolates; Guinea | 2005 |
Regional differences in gastrointestinal motility disturbances during acute necrotising pancreatitis.
Topics: Acute Disease; Animals; Carbachol; Choline Deficiency; Dietary Supplements; Dinoprost; Disease Model | 2005 |
Age-related alterations in the biochemical and functional properties of the bladder in type 2 diabetic GK rats.
Topics: Acetylcholine; Adenosine Triphosphate; Aging; Animals; Body Weight; Carbachol; Diabetes Complication | 2005 |
Isoquercitrin from Argemone platyceras inhibits carbachol and leukotriene D4-induced contraction in guinea-pig airways.
Topics: Acetates; Animals; Anti-Asthmatic Agents; Anti-Inflammatory Agents, Non-Steroidal; Argemone; Asthma; | 2005 |
Comparison of the urethral properties of the female guinea pig and rat.
Topics: Animals; Carbachol; Female; Guinea Pigs; In Vitro Techniques; Muscle Contraction; Parasympathomimeti | 2006 |
Aceclidine and pilocarpine interact differently with muscarinic receptor in isolated rabbit iris muscle.
Topics: Animals; Carbachol; Iris; Muscarinic Agonists; Muscle Contraction; Muscle, Smooth; Pilocarpine; Quin | 2006 |
M2 and M3 muscarinic receptor activation of urinary bladder contractile signal transduction. I. Normal rat bladder.
Topics: Animals; Benzofurans; Carbachol; Dose-Response Relationship, Drug; Enzyme Inhibitors; In Vitro Techn | 2006 |
M2 and M3 muscarinic receptor activation of urinary bladder contractile signal transduction. II. Denervated rat bladder.
Topics: Animals; Benzofurans; Carbachol; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; In Vit | 2006 |
Juvenile pig detrusor: effects of propiverine and three of its metabolites.
Topics: Animals; Atropine; Benzhydryl Compounds; Benzilates; Carbachol; Cresols; Dose-Response Relationship, | 2005 |
Absence of force suppression in rabbit bladder correlates with low expression of heat shock protein 20.
Topics: Adenylyl Cyclases; Animals; Carbachol; Carotid Arteries; Colforsin; Cyclic GMP; Enzyme Activation; H | 2005 |
Effect of rilmakalim on detrusor contraction in the presence and absence of urothelium.
Topics: Animals; Carbachol; Chromans; Dose-Response Relationship, Drug; Drug Interactions; Female; Humans; M | 2005 |
Peripherally administered CRF stimulates colonic motility via central CRF receptors and vagal pathways in conscious rats.
Topics: Afferent Pathways; Animals; Atropine; Carbachol; Colon; Consciousness; Corticotropin-Releasing Hormo | 2006 |
Role of plasma membrane Ca2+-ATPase in contraction-relaxation processes of the bladder: evidence from PMCA gene-ablated mice.
Topics: Animals; Calcium; Calcium-Transporting ATPases; Carbachol; Cation Transport Proteins; Cell Membrane; | 2006 |
Mechanism involved in the spasmolytic effect of a mixture of two triterpenes, cycloartenol and cycloeucalenol, isolated from Herissanthia tiubae in the guinea-pig ileum.
Topics: Animals; Aorta; Carbachol; Drug Combinations; Female; Guinea Pigs; Ileum; In Vitro Techniques; Male; | 2005 |
Rho kinase expression and its central role in ovine gallbladder contractions elicited by a variety of excitatory stimuli.
Topics: Amides; Animals; Carbachol; Dose-Response Relationship, Drug; Electric Stimulation; Gallbladder; In | 2005 |
Dietary fish oil dose-response effects on ileal phospholipid fatty acids and contractility.
Topics: Animals; Carbachol; Dietary Fats, Unsaturated; Dinoprostone; Docosahexaenoic Acids; Dose-Response Re | 2005 |
Cholinergic receptor and cyclic stretch-mediated inflammatory gene expression in intact ASM.
Topics: Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Carbachol; Cattle; Chemokine CCL2; Chol | 2006 |
Stimulation of soluble guanylyl cyclase by BAY 41-2272 relaxes anococcygeus muscle: interaction with nitric oxide.
Topics: Animals; Carbachol; Carbolines; Colforsin; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; | 2006 |
Glycycoumarin from Glycyrrhizae Radix acts as a potent antispasmodic through inhibition of phosphodiesterase 3.
Topics: Animals; Carbachol; Coumarins; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Glycyrrhiza | 2006 |
[Influence of carbachol on the kinetic parameters of the contractile response to noradrenaline in the rat vas deferens].
Topics: Adrenergic alpha-1 Receptor Agonists; Animals; Carbachol; In Vitro Techniques; Kinetics; Male; Model | 2005 |
Inhibitory effects of various L-type and T-type calcium antagonists on electrically generated, potassium-induced and carbachol-induced contractions of porcine detrusor muscle.
Topics: Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channels, T-Type; Carbachol; Ch | 2006 |
Lipid signaling changes in smooth muscle remodeling associated with partial urinary bladder outlet obstruction.
Topics: Animals; Arachidonic Acid; Carbachol; Chromatography, Thin Layer; In Vitro Techniques; Lipids; Male; | 2006 |
Inhibitory effect of the norlignan 2-(2'-hydroxy-4',6'-dimethoxyphenyl)-5-[(E)-propenyl]benzofuran from Krameria tomentosa on acetylcholine-induced relaxation of the rat aorta.
Topics: Acetylcholine; Animals; Aorta; Benzofurans; Carbachol; Endothelium; Female; Guinea Pigs; Ileum; In V | 2006 |
Muscarinic acetylcholine type-3 receptor desensitization due to chronic exposure to Sjögren's syndrome-associated autoantibodies.
Topics: Animals; Antibodies, Blocking; Autoantibodies; Carbachol; Disease Models, Animal; Dose-Response Rela | 2006 |
Developmental regulation of nerve and receptor mediated contractions of mammalian urinary bladder smooth muscle.
Topics: Adenosine Triphosphate; Age Factors; Amides; Animals; Animals, Newborn; Carbachol; Cholinergic Agoni | 2006 |
Muscarinic acetylcholine receptor subtypes in the rat seminal vesicle.
Topics: Animals; Carbachol; Immunohistochemistry; In Vitro Techniques; Male; Muscarinic Antagonists; Muscle | 2006 |
Pharmacological characterization of urinary bladder smooth muscle contractility following partial bladder outlet obstruction in pigs.
Topics: Adenosine Triphosphate; Amides; Animals; Benzophenones; Carbachol; Cholinergic Agonists; Cromakalim; | 2006 |
Role of Rho-kinase in guinea-pig gallbladder smooth muscle contraction.
Topics: Amides; Animals; Calcium; Calcium Channel Blockers; Calcium-Transporting ATPases; Carbachol; Cholecy | 2006 |
Increased cholinergic contractions of jejunal smooth muscle caused by a high cholesterol diet are prevented by the 5-HT4 agonist--tegaserod.
Topics: Action Potentials; Animals; Carbachol; Cholesterol, Dietary; Cholinergic Agonists; Disease Models, A | 2006 |
Impairment of PAR-2-mediated relaxation system in colonic smooth muscle after intestinal inflammation.
Topics: Animals; Apamin; Carbachol; Colitis; Colon; Dextran Sulfate; Dose-Response Relationship, Drug; In Vi | 2006 |
Cross-interaction between PAR-activation and tyrosine kinase in the modulation of rat ileum smooth muscle contraction.
Topics: Animals; Carbachol; Cholinergic Agonists; Ileum; In Vitro Techniques; Male; Muscle Contraction; Musc | 2006 |
Involvement of Rho kinase and protein kinase C in carbachol-induced calcium sensitization in beta-escin skinned rat and guinea-pig bladders.
Topics: Animals; Calcium; Carbachol; Escin; Guinea Pigs; Intracellular Signaling Peptides and Proteins; Musc | 2006 |
Inhibitory effects of magnolol on distal colon of guinea pig in vitro.
Topics: Anesthetics, Local; Animals; Biphenyl Compounds; Calcium Channel Blockers; Carbachol; Colon; Dose-Re | 2006 |
Inhibitory effects of L- and T-type calcium antagonists on contractions of human detrusor muscle.
Topics: Adult; Aged; Analysis of Variance; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Chann | 2006 |
BK channel beta1-subunit regulation of calcium handling and constriction in tracheal smooth muscle.
Topics: Animals; Calcium; Calcium Channels; Carbachol; Cholinergic Agonists; Electrophysiology; Large-Conduc | 2006 |
Control of intestinal motility by the Ca(v)1.2 L-type calcium channel in mice.
Topics: Animals; Calcium Channels, L-Type; Carbachol; Cholinergic Agonists; Gastrointestinal Motility; Intes | 2006 |
The influence of changes in extracellular and intracellular sodium concentration on detrusor contractility.
Topics: Animals; Calcium; Carbachol; Electric Stimulation; Extracellular Fluid; Guinea Pigs; Intracellular F | 2006 |
Muscarinic regulation of neonatal rat bladder spontaneous contractions.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 2006 |
Effects of cold storage on the function and morphology of isolated urinary bladder in rat.
Topics: Adenosine Triphosphate; Animals; Carbachol; Carbon Dioxide; Cholinergic Agonists; Cryopreservation; | 2006 |
Contribution of Rho-kinase in human gallbladder contractions.
Topics: Aged; Amides; Blotting, Western; Carbachol; Cholecystokinin; Dose-Response Relationship, Drug; Endot | 2006 |
Isolation and pharmacological characterisation of hostoxin-1, a postsynaptic neurotoxin from the venom of the Stephen's banded snake (Hoplocephalus stephensi).
Topics: Analysis of Variance; Animals; Animals, Newborn; Anoplura; Carbachol; Chickens; Cholinergic Agonists | 2006 |
Comparison study of autonomous activity in bladders from normal and paraplegic rats.
Topics: Animals; Arecoline; Carbachol; Cholinergic Agonists; Female; Muscarinic Agonists; Muscle Contraction | 2006 |
The role of tyrosine kinase in prostaglandin E2 and vanadate-evoked contractions in rabbit duodenum in vitro.
Topics: Animals; Calcium; Carbachol; Dinoprostone; Dose-Response Relationship, Drug; Duodenum; Estrenes; Gen | 2006 |
Antagonism by imidazoline-type drugs of muscarinic and other receptors in the guinea-pig ileum.
Topics: Animals; Carbachol; Cholinergic Agonists; Dose-Response Relationship, Drug; Guinea Pigs; Histamine; | 2006 |
Muscarinic receptor function, density and G-protein coupling in the overactive diabetic rat bladder.
Topics: Animals; Binding, Competitive; Carbachol; Diabetes Mellitus, Experimental; Dose-Response Relationshi | 2006 |
Regulation of bladder muscarinic receptor subtypes by experimental pathologies.
Topics: Age Factors; Animals; Benzofurans; Carbachol; Denervation; Disease Models, Animal; Electric Stimulat | 2006 |
In vitro tracheal hyperresponsiveness to muscarinic receptor stimulation by carbachol in a rat model of bleomycin-induced pulmonary fibrosis.
Topics: Animals; Bleomycin; Bronchial Hyperreactivity; Calcium Signaling; Carbachol; Disease Models, Animal; | 2006 |
Effects of dextromethorphan on in vitro contractile responses of mouse and rat urinary bladders.
Topics: Animals; Carbachol; Dextromethorphan; Electric Stimulation; In Vitro Techniques; Male; Mice; Muscari | 2006 |
Different effects of ATP on the contractile activity of mice diaphragmatic and skeletal muscles.
Topics: Adenosine Triphosphate; Animals; Carbachol; Denervation; Diaphragm; Female; Male; Membrane Potential | 2006 |
Ghrelin as a novel locally produced relaxing peptide of the iris sphincter and dilator muscles.
Topics: Animals; Anterior Eye Segment; Carbachol; Cholinergic Agonists; Dose-Response Relationship, Drug; Ep | 2006 |
Treatment with cyclohexenonic long-chain fatty alcohol reverses diabetes-induced tracheal dysfunction in the rat.
Topics: Animals; Body Weight; Carbachol; Diabetes Mellitus, Experimental; Fatty Alcohols; Female; Immunohist | 2006 |
Effect of partial bladder outlet obstruction on detrusor compliance, excitability and contractility in rats.
Topics: Animals; Carbachol; Compliance; Electric Stimulation; In Vitro Techniques; Male; Muscle Contraction; | 2006 |
Distinct roles of PMCA isoforms in Ca2+ homeostasis of bladder smooth muscle: evidence from PMCA gene-ablated mice.
Topics: Animals; Calcium; Carbachol; Dose-Response Relationship, Drug; Homeostasis; Intracellular Membranes; | 2007 |
The role of Ca2+ influx and intracellular Ca2+ release in the muscarinic-mediated contraction of mammalian urinary bladder smooth muscle.
Topics: Animals; Calcium; Calcium Channel Blockers; Calcium Channels; Carbachol; Guinea Pigs; Intracellular | 2006 |
Autonomous contractile activity in the isolated rat bladder is modulated by a TRPV1 dependent mechanism.
Topics: Animals; Carbachol; Cholinergic Agonists; Diterpenes; Electric Stimulation; Female; Muscle Contracti | 2007 |
A Rho-kinase inhibitor, Y-27632, reduces cholinergic contraction but not neurotransmitter release.
Topics: Amides; Animals; Carbachol; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guinea Pigs; In Vit | 2006 |
Enhancement of rat bladder contraction by artificial sweeteners via increased extracellular Ca2+ influx.
Topics: Adenosine Triphosphate; Animals; Aspartame; Atropine; Calcium; Calcium Channels, L-Type; Carbachol; | 2006 |
Propiverine and metabolites: differences in binding to muscarinic receptors and in functional models of detrusor contraction.
Topics: Animals; Benzilates; Binding, Competitive; Calcium; Carbachol; Cell Line; Cells, Cultured; CHO Cells | 2006 |
Ablation of connexin43 in smooth muscle cells of the mouse intestine: functional insights into physiology and morphology.
Topics: Animals; beta-Galactosidase; Body Weight; Carbachol; Cell Nucleus; Connexin 43; Gene Deletion; Gene | 2007 |
Effect of cold-induced stress on rat bladder tissue contractility and histomorphology.
Topics: Animals; Carbachol; Cell Count; Cold Temperature; Electric Stimulation; In Vitro Techniques; Male; M | 2007 |
Prostaglandin F2alpha, but not latanoprost, increases the Ca2+ sensitivity of the pig iris sphincter muscle.
Topics: Animals; Antihypertensive Agents; Calcium; Carbachol; Dinoprost; Enzyme Inhibitors; Intracellular Si | 2006 |
Azithromycin has a direct relaxant effect on precontracted airway smooth muscle.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Anti-Bacterial Agents; Atropine; Azithromycin; Bronchodilator | 2006 |
Origin of spontaneous activity in neonatal and adult rat bladders and its enhancement by stretch and muscarinic agonists.
Topics: Animals; Animals, Newborn; Atropine; Calcium Signaling; Carbachol; Diacetyl; Electric Stimulation; E | 2007 |
Fibre-free diet leads to impairment of neuronally mediated muscle contractile response in rat distal colon.
Topics: Animal Feed; Animals; Carbachol; Cell Count; Cholinergic Agonists; Colon; Dietary Fiber; Electric St | 2006 |
Functional roles of muscarinic M2 and M3 receptors in mouse stomach motility: studies with muscarinic receptor knockout mice.
Topics: Animals; Carbachol; Cholinergic Agonists; Dose-Response Relationship, Drug; Electric Stimulation; En | 2007 |
Do gap junctions play a role in nerve transmissions as well as pacing in mouse intestine?
Topics: 1-Octanol; Adenosine Triphosphate; Animals; Apamin; Atropine; Carbachol; Connexins; Electric Stimula | 2007 |
Smooth muscle caveolae differentially regulate specific agonist induced bladder contractions.
Topics: Angiotensin II; Animals; beta-Cyclodextrins; Bradykinin; Carbachol; Caveolae; Caveolin 1; Caveolin 2 | 2007 |
M2 mediated contractions of human bladder from organ donors is associated with an increase in urothelial muscarinic receptors.
Topics: Adolescent; Adult; Aged; Animals; Benzofurans; Carbachol; Child; Child, Preschool; Cholinergic Agoni | 2007 |
Effects of KP-496, a novel dual antagonist for leukotriene D4 and thromboxane A2 receptors, on contractions induced by various agonists in the guinea pig trachea.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetates; Acetylcholine; Albuter | 2006 |
Mechanism of reduced colonic contractility in experimental colitis: role of sarcoplasmic reticulum pump isoform-2.
Topics: Animals; Body Weight; Carbachol; Colitis; Dose-Response Relationship, Drug; Gastrointestinal Motilit | 2007 |
Human idiopathic and neurogenic overactive bladders and the role of M2 muscarinic receptors in contraction.
Topics: Adult; Aged; Benzofurans; Carbachol; Diamines; Dose-Response Relationship, Drug; Female; Humans; In | 2007 |
Role of protein kinase C in the effect of ATP on contractile function of the isolated strip from mouse diaphragm.
Topics: Adenosine; Adenosine Triphosphate; Alkaloids; Animals; Benzophenanthridines; Carbachol; Cardiotonic | 2006 |
PKC delta-isoform translocation and enhancement of tonic contractions of gastrointestinal smooth muscle.
Topics: Animals; Carbachol; Cytoplasm; Cytoskeleton; Diacylglycerol Kinase; Diterpenes; Female; Guinea Pigs; | 2007 |
Male sex hormones promote vagally mediated reflex airway responsiveness to cholinergic stimulation.
Topics: Animals; Bronchi; Bronchial Hyperreactivity; Carbachol; Dihydrotestosterone; Female; In Vitro Techni | 2007 |
Scavenging effect and antispasmodic activity of the essential oil of Cyclotrichium niveum.
Topics: Animals; Biphenyl Compounds; Carbachol; Dose-Response Relationship, Drug; Female; Free Radical Scave | 2007 |
BXL-628, a vitamin D receptor agonist effective in benign prostatic hyperplasia treatment, prevents RhoA activation and inhibits RhoA/Rho kinase signaling in rat and human bladder.
Topics: Animals; Calcitriol; Calcium; Carbachol; Cell Movement; Cholinergic Agonists; Drug Interactions; Enz | 2007 |
Differential roles of ryanodine- and thapsigargin-sensitive intracellular CA2+ stores in excitation-contraction coupling in smooth muscle of guinea-pig taenia caeci.
Topics: Animals; Calcium; Calcium Signaling; Carbachol; Cecum; Enzyme Inhibitors; Female; Guinea Pigs; Hista | 2006 |
Effect of short-term outlet obstruction on rat bladder nerve density and contractility.
Topics: Adenosine Triphosphate; Animals; Carbachol; In Vitro Techniques; Ligation; Male; Muscle Contraction; | 2007 |
Pharmacological characterization of a new antimuscarinic agent, solifenacin succinate, in comparison with other antimuscarinic agents.
Topics: Animals; Atropine; Benzhydryl Compounds; Benzilates; Benzofurans; Binding, Competitive; Carbachol; C | 2007 |
Protective effect of high-dose thiamine (B1) on rat detrusor contractility in streptozotocin-induced diabetes mellitus.
Topics: Animals; Blood Glucose; Body Weight; Carbachol; Diabetes Mellitus, Experimental; Diuresis; Male; Mus | 2006 |
Differential development of carbachol-induced desensitization in receptor-mediated Ca2+ influx and Ca2+ release pathways in smooth muscle of guinea-pig taenia caeci.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Animals; Calcium; Calcium Sign | 2007 |
TRPV1 is involved in stretch-evoked contractile changes in the rat autonomous bladder model: a study with piperine, a new TRPV1 agonist.
Topics: Alkaloids; Animals; Benzodioxoles; Capsaicin; Carbachol; Cholinergic Agonists; Dose-Response Relatio | 2007 |
Repeated allergen inhalation induces cytoskeletal remodeling in smooth muscle from rat bronchioles.
Topics: Actins; Allergens; Animals; Antineoplastic Agents; Asthma; Bridged Bicyclo Compounds, Heterocyclic; | 2007 |
Theoretical and experimental investigation of calcium-contraction coupling in airway smooth muscle.
Topics: Androstadienes; Animals; Azepines; Calcium; Carbachol; Cholinergic Agents; Enzyme Activation; In Vit | 2006 |
Effect of (R)-2-(2-aminothiazol-4-yl)-4'-{2-[(2-hydroxy-2-phenylethyl)amino]ethyl} acetanilide (YM178), a novel selective beta3-adrenoceptor agonist, on bladder function.
Topics: Acetanilides; Adrenergic beta-3 Receptor Agonists; Adrenergic beta-Agonists; Animals; Carbachol; CHO | 2007 |
Gender-related neuronal and smooth muscle damage of guinea pig isolated urinary bladder from anoxia-glucopenia and reperfusion injury and its relationship to glycogen content.
Topics: Adenosine Triphosphate; Animals; Carbachol; Cholinergic Agonists; Deoxyglucose; Female; Glucose; Gly | 2007 |
A minor role for Ca2+ sensitization in sustained contraction through activation of muscarinic receptor in circular muscle of rat distal colon.
Topics: Alkaloids; Amides; Animals; Benzophenanthridines; Calcium; Carbachol; Carcinogens; Cholinergic Agoni | 2007 |
Using caveolin-1 knockout mouse to study impaired detrusor contractility and disrupted muscarinic activity in the aging bladder.
Topics: Aging; Animals; Carbachol; Caveolin 1; Disease Models, Animal; Electric Stimulation; Male; Mice; Mic | 2007 |
Attenuation of contractile dysfunction by atorvastatin after intestinal ischemia reperfusion injury in rats.
Topics: Administration, Oral; Animals; Atorvastatin; Carbachol; Cholinergic Agonists; Dose-Response Relation | 2007 |
Contribution of Ca2+ influx to carbachol-induced detrusor contraction is different in human urinary bladder compared to pig and mouse.
Topics: Aged; Animals; Boron Compounds; Calcium; Calcium Channels, L-Type; Carbachol; Dose-Response Relation | 2007 |
Cytokine modulation of muscarinic receptors in the murine intestine.
Topics: Animals; Carbachol; Interferon gamma Receptor; Interferon-gamma; Jejunum; Male; Mice; Mice, Inbred C | 2007 |
Esophageal smooth muscle reactivity is impaired in chronic reflux esophagitis by both receptor- and nonreceptor-mediated mechanisms.
Topics: Animals; Calcium Channels; Carbachol; Cholinergic Agonists; Dose-Response Relationship, Drug; Esopha | 2007 |
Effect of chronic renal failure on foregut smooth muscle reactivity: an experimental study.
Topics: Adrenergic beta-Agonists; Animals; Carbachol; Cholinergic Agonists; Dose-Response Relationship, Drug | 2007 |
Succinylcholine potentiates acetylcholine-induced contractile and phosphatidylinositol responses of rat trachea.
Topics: Acetylcholine; Animals; Carbachol; Kinetics; Male; Muscle Contraction; Muscle, Smooth; Phosphatidyli | 2007 |
Pharmacological effects of imidafenacin (KRP-197/ONO-8025), a new bladder selective anti-cholinergic agent, in rats. Comparison of effects on urinary bladder capacity and contraction, salivary secretion and performance in the Morris water maze task.
Topics: Animals; Carbachol; Cholinergic Antagonists; Cognition Disorders; Female; Imidazoles; In Vitro Techn | 2007 |
Intracellular calcium stores in beta-escin skinned rat and guinea-pig bladders.
Topics: Animals; Caffeine; Calcium; Calmodulin; Carbachol; Cecum; Escin; Guanosine Triphosphate; Guinea Pigs | 2007 |
Dimethyl sulphoxide relaxes rabbit detrusor muscle by decreasing the Ca2+ sensitivity of the contractile apparatus.
Topics: Actins; Analgesics, Non-Narcotic; Androstadienes; Animals; Aorta; Calcium; Calmodulin; Carbachol; Ch | 2007 |
Involvement of CPI-17 downregulation in the dysmotility of the colon from dextran sodium sulphate-induced experimental colitis in a mouse model.
Topics: Animals; Anticoagulants; Blotting, Western; Carbachol; Cholinergic Agonists; Colitis; Dextran Sulfat | 2007 |
Does phospholipase C mediate muscarinic receptor-induced rat urinary bladder contraction?
Topics: Animals; Carbachol; Muscle Contraction; Muscle, Smooth; Neomycin; Rats; Receptor, Muscarinic M3; Rec | 2007 |
Evaluation of the cholinergic and adrenergic effects of two tropane alkaloids from Erythroxylum pervillei.
Topics: Adrenergic Agents; Adrenergic alpha-Agonists; Alkaloids; Animals; Aorta; Carbachol; Cholinergic Agen | 2007 |
The extracorporeal perfusion of the female pig detrusor as an experimental model for the study of bladder contractility.
Topics: Animals; Blood Pressure; Carbachol; Cholinergic Agonists; Dose-Response Relationship, Drug; Female; | 2007 |
Pre- and postsynaptic mechanisms in the clonidine- and oxymetazoline-induced inhibition of gastric motility in the rat.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Carbachol; Clonidine; Gastrointest | 2007 |
Changes in urinary bladder smooth muscle function in response to colonic inflammation.
Topics: Animals; Carbachol; Cholinergic Agonists; Colitis; Electric Stimulation; Enema; Male; Mucous Membran | 2007 |
Functional evaluation of the grafted wall with porcine-derived small intestinal submucosa (SIS) to a stomach defect in rats.
Topics: Animals; Carbachol; Cell Movement; Cholinergic Agonists; Cholinergic Antagonists; Electric Stimulati | 2007 |
Desensitization of guinea-pig taenia caeci smooth muscle induced by a low concentration of carbachol.
Topics: Animals; Calcium; Carbachol; Cecum; Dose-Response Relationship, Drug; Guinea Pigs; In Vitro Techniqu | 2007 |
Intracellular calcium mobilization of the aganglionic intestine in the endothelin B receptor gene-deficient rat.
Topics: Animals; Calcium Channels, L-Type; Calcium Signaling; Carbachol; Cholinergic Agonists; Colon; Diseas | 2007 |
Transient resensitization interrupting the development of carbachol-induced desensitization in smooth muscle of guinea-pig taenia caeci: Ca2+-dependent termination of resensitization.
Topics: Animals; Calcium; Carbachol; Cecum; Guinea Pigs; In Vitro Techniques; Muscle Contraction; Muscle, Sm | 2007 |
Phagocytotic activation of muscularis resident macrophages inhibits smooth muscle contraction in rat ileum.
Topics: Animals; Carbachol; Cyclooxygenase 2; Dextrans; Enzyme Induction; Female; Ileum; Indomethacin; Macro | 2007 |
Gliadin-dependent neuromuscular and epithelial secretory responses in gluten-sensitive HLA-DQ8 transgenic mice.
Topics: Acetylcholine; Animals; Antibodies; Carbachol; Celiac Disease; Cholinergic Agonists; Disease Models, | 2008 |
The in vitro neurotoxic and myotoxic effects of the venom from the Suta genus (curl snakes) of elapid snakes.
Topics: Acetylcholine; Animals; Antivenins; Australia; Carbachol; Chickens; Dose-Response Relationship, Drug | 2007 |
A highly efficient method to differentiate smooth muscle cells from human embryonic stem cells.
Topics: Carbachol; Cell Culture Techniques; Cell Differentiation; Cell Lineage; Cell Shape; Cells, Cultured; | 2007 |
Role of Ca2+-sensitization in attenuated carbachol-induced contraction of the colon in a rat model of colitis.
Topics: Animals; Blotting, Western; Calcium; Carbachol; Colitis; Colon; Disease Models, Animal; Gene Express | 2008 |
Muscarinic receptor subtypes involved in carbachol-induced contraction of mouse uterine smooth muscle.
Topics: Animals; Carbachol; Cholinergic Agonists; Dose-Response Relationship, Drug; Estrous Cycle; Female; M | 2008 |
In vitro sensitivity of mouse esophagus to agonists in different pH medium values.
Topics: Acetylcholine; Adrenergic beta-Agonists; Analysis of Variance; Animals; Carbachol; Cholinergic Agoni | 2007 |
The effect of partial bladder outlet obstruction on carbonyl and nitrotyrosine distribution in rabbit bladder.
Topics: Animals; Carbachol; Electric Stimulation; In Vitro Techniques; Male; Mucous Membrane; Muscle Contrac | 2007 |
Pharmacological effects of propiverine and its active metabolite, M-1, on isolated human urinary bladder smooth muscle, and on bladder contraction in rats.
Topics: Aged; Animals; Benzhydryl Compounds; Benzilates; Carbachol; Cholinergic Agonists; Cresols; Cyclic N- | 2008 |
The obestatin/ghrelin system as a novel regulatory mechanism of iris muscle contraction.
Topics: Animals; Carbachol; Dose-Response Relationship, Drug; Electric Stimulation; Epinephrine; Ghrelin; Ir | 2008 |
Does tourniquet application alter the nitrergic responses of rabbit corpus cavernosum penis? A functional study.
Topics: Animals; Carbachol; Cholinergic Agonists; Electric Stimulation; Endothelium; Male; Models, Animal; M | 2008 |
Inhibitory effects of different ATP-sensitive potassium channel openers on electrically generated and carbachol-induced contractions of porcine and human detrusor muscle.
Topics: Aged; Amides; Animals; Benzophenones; Carbachol; Cromakalim; Electric Stimulation; Female; Humans; I | 2008 |
Gastrointestinal, selective airways and urinary bladder relaxant effects of Hyoscyamus niger are mediated through dual blockade of muscarinic receptors and Ca2+ channels.
Topics: Animals; Calcium Channel Blockers; Carbachol; Castor Oil; Diarrhea; Female; Guinea Pigs; Hyoscyamus; | 2008 |
Cholinergic responses of ileal longitudinal muscle under short-lasting exposure to cupric ions.
Topics: Animals; Atropine; Carbachol; Cholinergic Agonists; Cholinergic Fibers; Copper; Diphenhydramine; Dos | 2008 |
Contractile properties of the pig bladder mucosa in response to neurokinin A: a role for myofibroblasts?
Topics: Animals; Carbachol; Dose-Response Relationship, Drug; Fibroblasts; Immunohistochemistry; Mucous Memb | 2008 |
Assessment of muscarinic receptor subtypes in human and rat lower urinary tract by tissue segment binding assay.
Topics: Aged; Animals; Carbachol; Cell Membrane; Female; Humans; In Vitro Techniques; Male; Middle Aged; Muc | 2008 |
Interleukin 13 increases contractility of murine tracheal smooth muscle by a phosphoinositide 3-kinase p110delta-dependent mechanism.
Topics: Adenine; Animals; Bronchial Hyperreactivity; Carbachol; Chromones; Class I Phosphatidylinositol 3-Ki | 2008 |
Effect of co-enzyme Q10 and alpha-lipoic acid on response of rabbit urinary bladder to repetitive stimulation and in vitro ischemia.
Topics: Animals; Antioxidants; Carbachol; Electric Stimulation; Electron Transport Chain Complex Proteins; I | 2008 |
Long-term nitric oxide deficiency causes muscarinic supersensitivity and reduces beta(3)-adrenoceptor-mediated relaxation, causing rat detrusor overactivity.
Topics: Adrenergic beta-3 Receptor Agonists; Adrenergic beta-Agonists; Animals; Carbachol; Inositol Phosphat | 2008 |
Damaging effects of intense repetitive treadmill running on murine intestinal musculature.
Topics: Animals; Antioxidants; Bradykinin; Carbachol; Ileum; Intestines; Isometric Contraction; Lactic Acid; | 2008 |
Gastric motor effects of ghrelin and growth hormone releasing peptide 6 in diabetic mice with gastroparesis.
Topics: Alloxan; Animals; Carbachol; Cholinergic Agents; Diabetes Mellitus, Experimental; Disease Models, An | 2008 |
Effect of menthol on detrusor smooth-muscle contraction and the micturition reflex in rats.
Topics: Animals; Antipruritics; Capsaicin; Carbachol; Female; Menthol; Muscle Contraction; Muscle, Smooth; R | 2008 |
Association of overactive bladder and stress urinary incontinence in rats with pudendal nerve ligation injury.
Topics: Adrenergic alpha-Agonists; Animals; Capsaicin; Carbachol; Enzyme-Linked Immunosorbent Assay; Female; | 2008 |
The use of occupation isoboles for analysis of a response mediated by two receptors: M2 and M3 muscarinic receptor subtype-induced mouse stomach contractions.
Topics: Animals; Atropine; Carbachol; Cholinergic Agonists; In Vitro Techniques; Mice; Mice, Knockout; Musca | 2008 |
Neutering affects urinary bladder function by different mechanisms in male and female dogs.
Topics: Animals; Carbachol; Collagen; Dog Diseases; Dogs; Dose-Response Relationship, Drug; Electric Stimula | 2008 |
Effect of eviprostat on bladder overactivity in an experimental cystitis rat model.
Topics: Animals; Antineoplastic Agents, Alkylating; Carbachol; Cholinergic Agonists; Cyclophosphamide; Cysti | 2008 |
Changes to the contractile function of ureter smooth muscle after partial infravesical obstruction in fetal sheep.
Topics: Animals; Carbachol; Cholinergic Agonists; Fetus; Male; Muscle Contraction; Muscle, Smooth; Potassium | 2008 |
Neurotoxic and insecticidal properties of venom from the Australian theraphosid spider Selenotholus foelschei.
Topics: Acetylcholine; Algorithms; Animals; Carbachol; Chick Embryo; Dose-Response Relationship, Drug; Femal | 2008 |
Pharmacological effects of solifenacin on human isolated urinary bladder.
Topics: Aged; Calcium Chloride; Carbachol; Dose-Response Relationship, Drug; Electric Stimulation; Female; H | 2008 |
Inhibition by tianeptine of neuronally mediated contractions in the rat isolated gastrointestinal tract.
Topics: Animals; Antidepressive Agents, Tricyclic; Carbachol; Colon; Electric Stimulation; Gastrointestinal | 2008 |
The role of alpha- and beta- adrenergic receptors in some actions of catecholamines on intestinal smooth muscle.
Topics: Animals; Carbachol; Cecum; Cell Membrane Permeability; Chlorides; Electrophysiology; Guinea Pigs; In | 1967 |
Mode of anticholinergic action of local anaesthetics.
Topics: Acetylcholine; Animals; Anura; Atropine; Biological Transport, Active; Caffeine; Carbachol; Cell Mem | 1967 |
A nonadrenergic musculotropic effect of 2-(cyclohexylamino)-ethylguanidine sulfate (SU-9707) in rabbit aortic strips.
Topics: Acetylcholine; Animals; Aorta; Atropine; Carbachol; Guanethidine; Guanidines; Histamine; In Vitro Te | 1967 |
The response of the isolated iris sphincter muscle of various mammalian species to substance P.
Topics: Animals; Carbachol; Cats; Cattle; Dogs; Dose-Response Relationship, Drug; Humans; In Vitro Technique | 1984 |
Temporal relationship of cyclic nucleotide levels and calcium exchange to histamine-induced tension development.
Topics: Animals; Calcium; Carbachol; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Guinea Pigs; | 1984 |
Differential effects of phenylmethanesulfonyl fluoride (PMSF) on carbachol and potassium stimulated phosphoinositide turnover and contraction in longitudinal smooth muscle of guinea pig ileum.
Topics: Animals; Carbachol; Female; Guinea Pigs; Ileum; Inositol; Kinetics; Muscle Contraction; Muscle, Smoo | 1984 |
The effect of alteration in temperature on contractile responses in human airways in vitro.
Topics: Animals; Bronchi; Carbachol; Guinea Pigs; Histamine; Humans; Ion Channels; Muscle Contraction; Muscl | 1984 |
Differences in responses of guinea-pig and rabbit airway smooth muscle to adrenaline and adrenergic nerve stimulation.
Topics: Acetylcholine; Animals; Bronchi; Carbachol; Electric Stimulation; Epinephrine; Guinea Pigs; Lung; Mi | 1980 |
Are the pA2 values of selective beta-adrenoceptor antagonists valid when obtained on guinea-pig tracheal preparations contracted with carbachol?
Topics: Adrenergic beta-Antagonists; Animals; Carbachol; Female; Guinea Pigs; Muscle Contraction; Receptors, | 1980 |
Parainfluenza 3 infection blocks the ability of a beta adrenergic receptor agonist to inhibit antigen-induced contraction of guinea pig isolated airway smooth muscle.
Topics: Adrenergic beta-Agonists; Animals; Asthma; Benzyl Alcohols; Benzyl Compounds; Bronchi; Carbachol; Fe | 1981 |
Slow-reacting substances (leukotrienes) contract human airway and pulmonary vascular smooth muscle in vitro.
Topics: Airway Resistance; Arachidonic Acids; Autacoids; Carbachol; Chromones; Ethers; Histamine; Humans; In | 1981 |
Potentiation and inhibition of nicotinic effects on striated muscle by the tetramine disulfide benextramine.
Topics: Acetylcholine; Adrenergic alpha-Antagonists; Animals; Anura; Carbachol; Cystamine; Drug Synergism; I | 1980 |
Anticholinesterase effect of sotalol.
Topics: Abdominal Muscles; Acetylcholine; Adrenergic beta-Antagonists; Animals; Carbachol; Cholinesterase In | 1981 |
Effects of adrenergic and cholinergic drugs on electrical and mechanical activities of the rat cauda epididymidis in vitro.
Topics: Action Potentials; Adrenergic Agonists; Animals; Atropine; Autonomic Agents; Carbachol; Epididymis; | 1981 |
Schistosoma mansoni: neurotransmitters, longitudinal musculature and effects of electrical stimulation.
Topics: Acetylcholine; Animals; Carbachol; Dopamine; Electric Stimulation; Male; Muscle Contraction; Neurotr | 1981 |
Bordetella pertussis-induced impairment of relaxation of rat trachea to isoprenaline and histamine and its reversal with hydrocortisone.
Topics: Animals; Carbachol; Histamine; Histamine H2 Antagonists; Hydrocortisone; Isoproterenol; Male; Muscle | 1982 |
Beta-adrenoreceptors of the cat nictitating membrane.
Topics: Acetylcholine; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Carbachol; Cats; Fema | 1981 |
Effect of atropine on the rat anococcygeus muscle.
Topics: Animals; Atropine; Carbachol; Drug Interactions; In Vitro Techniques; Male; Methysergide; Muscle Con | 1982 |
Effect of physostigmine and cocaine on noradrenaline-induced contractions of the rat anococcygeus muscle.
Topics: Acetylcholine; Animals; Carbachol; Cocaine; Drug Interactions; In Vitro Techniques; Male; Muscle Con | 1982 |
An inhibitory effect of histamine on the rat anococcygeus muscle.
Topics: Acetylcholine; Animals; Carbachol; Cimetidine; Dimaprit; Drug Interactions; Guanidines; Histamine; I | 1982 |
Histamine H1- and muscarinic receptor antagonist activity of cimetidine and tiotidine in the guinea pig isolated ileum.
Topics: Animals; Carbachol; Cimetidine; Guanidines; Guinea Pigs; Histamine; Histamine H1 Antagonists; Ileum; | 1981 |
Pharmacological responses by different portions of guinea pig vas deferens circular muscle preparation.
Topics: Acetylcholine; Adrenergic beta-Antagonists; Animals; Barium; Barium Compounds; Carbachol; Chlorides; | 1981 |
Phentolamine inhibition of rat seminal vesicle response to dopamine-mimetic drugs: alpha-adrenoceptor implication or lack of specificity?
Topics: Animals; Apomorphine; Carbachol; Catecholamines; Dopamine; Haloperidol; Imidazolines; In Vitro Techn | 1982 |
Pharmacological isolation of a single beta-adrenoceptor subtype makes Schild plots which have slopes of 1 possible for selective beta-adrenoceptor antagonists in carbachol-contracted guinea-pig trachea.
Topics: Adrenergic beta-Antagonists; Animals; Butoxamine; Carbachol; Guinea Pigs; In Vitro Techniques; Kinet | 1982 |
The binding of [3H]-diazepam to guinea-pig ileal longitudinal muscle and the in vitro inhibition of contraction by benzodiazepines.
Topics: Animals; Anti-Anxiety Agents; Binding, Competitive; Carbachol; Diazepam; Electric Stimulation; Guine | 1983 |
The feline carotid rete: vasomotor reactivity of isolated arteries.
Topics: Acetylcholine; Angiotensin II; Animals; Carbachol; Carotid Artery, External; Cats; Dinoprost; Female | 1983 |
Increase in muscarinic acetylcholine receptors in mouse intestine by hexamethonium treatment.
Topics: Animals; Brain; Carbachol; Female; Hexamethonium; Hexamethonium Compounds; Ileum; Intestinal Mucosa; | 1983 |
Assessment of potential selectivity of antispasmodics for the various sections of the gastrointestinal tract of the rat as a guideline for their clinical use.
Topics: Animals; Antihypertensive Agents; Butylscopolammonium Bromide; Carbachol; Digestive System; Digestiv | 1983 |
The role of myosin light chain kinase phosphorylation in beta-adrenergic relaxation of tracheal smooth muscle.
Topics: Adrenergic beta-Agonists; Animals; Carbachol; Cattle; Cyclic AMP; In Vitro Techniques; Isoproterenol | 1983 |
Inhibition of sympathetic neurotransmission in the rat anococcygeus muscle by diazepam.
Topics: Adenosine Triphosphate; Animals; Carbachol; Diazepam; Dipyridamole; Electric Stimulation; In Vitro T | 1983 |
Inhibition of cholinergic response by taurine in frog isolated skeletal muscle.
Topics: Animals; Caffeine; Carbachol; In Vitro Techniques; Muscle Contraction; Parasympatholytics; Rana temp | 1984 |
Effects of adrenaline and carbachol on the morphology of alveolar contractile cells in the lung of the toad (Bufo marinus).
Topics: Animals; Bufo marinus; Carbachol; Cell Nucleus; Epinephrine; Female; Male; Muscle Contraction; Muscl | 1984 |
A possible explanation for effects of Sr2+ on contraction-relaxation cycle in canine stomach.
Topics: Adenosine Triphosphate; Animals; Calcium; Carbachol; Cell Membrane; Dogs; Muscle Contraction; Muscle | 1984 |
Mechanical trauma to bladder epithelium liberates prostanoids which modulate neurotransmission in rabbit detrusor muscle.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Bethanechol; Bethanechol Compounds; Carbachol; Dose-Response | 1984 |
Non-specific, time-dependent desensitization of the vas deferens and anococcygeus preparations of the rat to alpha 1-adrenoceptor antagonists and atropine.
Topics: Adrenergic alpha-Antagonists; Animals; Atropine; Carbachol; In Vitro Techniques; Kinetics; Male; Mox | 1984 |
Photodynamic effects of erythrosine on the smooth muscle cells of guinea-pig taenia coli.
Topics: Action Potentials; Animals; Calcium; Carbachol; Cell Membrane Permeability; Colon; Erythrosine; Fema | 1984 |
Pharmacological and biochemical evidence for metabolism of peptide leukotrienes by guinea-pig airway smooth muscle in vitro.
Topics: Aminopeptidases; Animals; Carbachol; Cysteine; Dose-Response Relationship, Drug; gamma-Glutamyltrans | 1984 |
The antagonism of histamine-induced tracheal and bronchial muscle contraction by diphenhydramine: effect of maturation.
Topics: Aging; Animals; Bronchi; Carbachol; Diphenhydramine; Guinea Pigs; Histamine; Histamine Antagonists; | 1984 |
The contractile effect of bombesin on the rat isolated urinary bladder.
Topics: Animals; Bombesin; Bradykinin; Carbachol; Dose-Response Relationship, Drug; Female; In Vitro Techniq | 1981 |
Oxygen dependence of contractions in esophageal and gastric pyloric and ileocecal muscle of opossums.
Topics: Animals; Carbachol; Digestive System Physiological Phenomena; Esophagogastric Junction; Esophagus; F | 1982 |
Sensory neural mechanisms in contraction of the isolated sphincter pupillae: the role for substance P and the effects of sensory denervation on the responses to miotics.
Topics: Animals; Bradykinin; Capsaicin; Carbachol; Dose-Response Relationship, Drug; Female; In Vitro Techni | 1982 |
Pharmacological effects of peptides on tracheal smooth muscle.
Topics: Animals; Carbachol; Female; Guinea Pigs; Histamine; In Vitro Techniques; Indomethacin; Male; Muscle | 1982 |
Trigeminal nerve: the possible origin of substance p-nergic response in isolated rabbit iris sphincter muscle.
Topics: Animals; Bradykinin; Capsaicin; Carbachol; Electric Stimulation; Enkephalins; Female; In Vitro Techn | 1982 |
Effects of Met-enkephalin on the substance P-ergic and cholinergic responses in the rabbit iris sphincter muscle.
Topics: Animals; Carbachol; Choline; Dose-Response Relationship, Drug; Electric Stimulation; Enkephalin, Met | 1983 |
Immunohistochemical localization of substance P, vasoactive intestinal polypeptide and gastrin-releasing peptide in vas deferens and seminal vesicle, and the effect of these and eight other neuropeptides on resting tension and neurally evoked contractile
Topics: Animals; Carbachol; Dopamine; Gastrin-Releasing Peptide; Gastrointestinal Hormones; Male; Mice; Moto | 1983 |
Vasoactive intestinal polypeptide influence on lower urinary tract smooth muscle from human and pig.
Topics: Animals; Carbachol; Dinoprost; Dinoprostone; Dose-Response Relationship, Drug; Female; Humans; In Vi | 1984 |
A study of [D-Pro2, D-Phe7, D-Trp9]-substance P and [D-Trp7,9]-substance P as tachykinin partial agonists in the rat colon.
Topics: Adsorption; Animals; Carbachol; Colon; Drug Interactions; In Vitro Techniques; Kassinin; Male; Muscl | 1984 |
Capsaicin and bradykinin-induced substance P-ergic responses in the iris sphincter muscle of the rabbit.
Topics: Animals; Atropine; Bradykinin; Capsaicin; Carbachol; Electric Stimulation; Female; Guanethidine; Iri | 1984 |
Supersensitivity of the rabbit iris sphincter muscle induced by trigeminal denervation: the role of substance P.
Topics: Action Potentials; Animals; Carbachol; Electric Stimulation; Female; Iris; Male; Muscle Contraction; | 1984 |
Studies on the relationship between contraction and mediator release produced by ovalbumin in superfused trachea isolated from the actively sensitized guinea pig.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Carbachol; Chromones; Dose-Response Relationship, Drug; Fe | 1984 |
Biological evaluation of substance P antagonists.
Topics: Animals; Bombesin; Carbachol; Colon; Electric Stimulation; Guinea Pigs; Histamine Release; In Vitro | 1984 |
Electrophysiological basis of excitation of canine colonic circular muscle by cholinergic agents and substance P.
Topics: Acetylcholine; Action Potentials; Animals; Atropine; Carbachol; Colon; Dogs; Female; In Vitro Techni | 1984 |
Autacoid and autonomic reactivity of bovine and ovine bronchus: modifications by antigenic sensitization.
Topics: Animals; Bronchi; Carbachol; Cattle; Dimaprit; Dose-Response Relationship, Drug; Epinephrine; Histam | 1982 |
A comparison of the stimulant activities of oxotremorine analogues on the frog rectus abdominis and the guinea pig ileum.
Topics: Abdominal Muscles; Animals; Carbachol; Guinea Pigs; Ileum; In Vitro Techniques; Muscle Contraction; | 1984 |
Effect of ketamine on transmission in sympathetic ganglia.
Topics: Abdominal Muscles; Animals; Anura; Carbachol; Dose-Response Relationship, Drug; Ganglia, Sympathetic | 1980 |
Effects of delta 9-tetrahydrocannabinol on excitable membranes and neuromuscular transmission.
Topics: Action Potentials; Animals; Anura; Carbachol; Dronabinol; In Vitro Techniques; Motor Endplate; Muscl | 1980 |
The use of guinea pig K+-depolarized tracheal chain preparations in beta-adrenoceptor studies.
Topics: Animals; Carbachol; Catecholamines; Female; Guinea Pigs; In Vitro Techniques; Isoproterenol; Muscle | 1980 |
Effect of Bordetella pertussis vaccination in mice and the isolated tracheal response to isoprenaline.
Topics: Animals; Asthma; Bordetella pertussis; Carbachol; Histamine; Injections, Intraperitoneal; Isoprotere | 1980 |
Delta-9-tetrahydrocannabinol on isolated human bronchioles.
Topics: Adolescent; Aged; Bronchodilator Agents; Carbachol; Child; Child, Preschool; Dronabinol; Drug Intera | 1980 |
Actions of 4-methyl-2-aminopyridine on neuromuscular transmission and contractility of skeletal muscle.
Topics: Acetylcholine; Animals; Carbachol; Chick Embryo; Cholinesterase Inhibitors; Electric Stimulation; Fe | 1981 |
Contribution of vascular smooth muscle to contractile responses of guinea-pig isolated lung parenchymal strips.
Topics: Animals; Carbachol; Electric Stimulation; Female; Guinea Pigs; In Vitro Techniques; Lung; Methoxamin | 1981 |
Relationship between contraction and cyclic GMP levels of guinea pig taenia coli.
Topics: Animals; Calcium; Carbachol; Cyclic GMP; Guinea Pigs; In Vitro Techniques; Intestines; Muscle Contra | 1981 |
Evidence that histamine and carbachol may open the same ion channels in longitudinal smooth muscle of guinea-pig ileum.
Topics: Animals; Carbachol; Electric Conductivity; Female; Guinea Pigs; Histamine; Ileum; In Vitro Technique | 1981 |
Disopyramide anticholinergic action.
Topics: Abdominal Muscles; Animals; Carbachol; Disopyramide; Dose-Response Relationship, Drug; Guinea Pigs; | 1981 |
Regulation of myosin light chain and phosphorylase phosphorylation in tracheal smooth muscle.
Topics: Animals; Calcium; Calmodulin; Carbachol; Cattle; Cyclic AMP; Kinetics; Molecular Weight; Muscle Cont | 1982 |
Cholecystokinin-induced contraction of dispersed smooth muscle cells.
Topics: Animals; Appetite Depressants; Biological Transport, Active; Calcimycin; Carbachol; Cholecystokinin; | 1982 |
Phosphorylation of myosin light chain in skeletal and smooth muscles.
Topics: Animals; Carbachol; Dose-Response Relationship, Drug; Muscle Contraction; Muscle, Smooth; Muscles; M | 1983 |
Relaxant beta-receptors in the trachea, but not prejunctional alpha 2-receptors in the tracheal cholinergic neurones, are subjected to homologous desensitization.
Topics: Animals; Carbachol; Guinea Pigs; Isoproterenol; Male; Muscle Contraction; Muscle, Smooth; Neurons; P | 1982 |
Capsaicin-sensitive non-cholinergic excitatory innervation of the guinea-pig tracheobronchial smooth muscle.
Topics: Animals; Bronchi; Capsaicin; Carbachol; Fatty Acids, Unsaturated; Female; Guinea Pigs; Male; Muscle | 1982 |
Evidence that ionic channels associated with the muscarinic receptor of smooth muscle may admit calcium.
Topics: Animals; Calcium; Carbachol; Electric Stimulation; Female; Guinea Pigs; In Vitro Techniques; Ion Cha | 1983 |
Augmentation of acetylcholine response in denervated skeletal muscle by endorphins and spinal cord-conditioned culture media.
Topics: Acetylcholine; Acetylcholinesterase; Animals; beta-Endorphin; beta-Lipotropin; Carbachol; Cholineste | 1983 |
Serotonin induced release of acetylcholine from neurons in the bronchial smooth muscle of the rat.
Topics: Acetylcholine; Animals; Atropine; Bronchi; Carbachol; Female; Methysergide; Muscle Contraction; Musc | 1983 |
Effect of ketamine on cholinergic transmission in the isolated guinea-pig ileum preparation.
Topics: Animals; Calcium; Carbachol; Electric Stimulation; Female; Guinea Pigs; Ileum; In Vitro Techniques; | 1983 |
Hyperreactive airway smooth muscle responsiveness after inhalation of toluene diisocyanate vapors.
Topics: Animals; Carbachol; Cyanates; Dose-Response Relationship, Drug; Guinea Pigs; In Vitro Techniques; Is | 1984 |
[The contraction of intestinal myocells and block of cationic pumps].
Topics: Animals; Carbachol; Deslanoside; Guinea Pigs; Ileum; Kinetics; Muscle Contraction; Muscle, Smooth; S | 1983 |
Cholinergic inhibition of adrenergic transmission in the dog retractor penis muscle.
Topics: Animals; Carbachol; Dogs; Electric Stimulation; Electrophysiology; In Vitro Techniques; Male; Membra | 1984 |
Steric aspects of agonism and antagonism at beta-adrenoceptors: experiments with the enantiomers of terbutaline and pindolol.
Topics: Animals; Carbachol; Guinea Pigs; In Vitro Techniques; Isoproterenol; Male; Muscle Contraction; Muscl | 1984 |
The conversion of 2-chloroalkylamine analogues of oxotremorine to aziridinium ions and their interactions with muscarinic receptors in the guinea pig ileum.
Topics: Alkylation; Animals; Aziridines; Azirines; Binding, Competitive; Carbachol; Chlorides; Guinea Pigs; | 1984 |
The relationship between bronchial hyperresponsiveness to methacholine and airway smooth muscle structure and reactivity.
Topics: Adult; Aged; Asthma; Bronchi; Carbachol; Female; Forced Expiratory Volume; Histamine; Humans; In Vit | 1984 |
Mechanisms of action of noradrenaline and carbachol on smooth muscle of guinea-pig anterior mesenteric artery.
Topics: Action Potentials; Adenosine Triphosphate; Animals; Calcimycin; Carbachol; Electric Conductivity; Gu | 1984 |
Vagal control of gall-bladder contraction.
Topics: Animals; Atropine; Carbachol; Dogs; Gallbladder; Gastrointestinal Motility; Hydrogen-Ion Concentrati | 1984 |
Assessment of smooth muscle toxicity in Cassia occidentalis toxicosis.
Topics: Animals; Carbachol; Cassia; Chickens; Ileal Diseases; Lung Diseases; Muscle Contraction; Muscle, Smo | 1984 |
Cholinergic responses in the human lung parenchymal strip: a structure-function correlation.
Topics: Aged; Carbachol; Female; Histamine; Humans; Indomethacin; Lung; Male; Middle Aged; Muscle Contractio | 1984 |
The effects and interactions of caffeine, lignocaine and carbachol at the chick neuromuscular junction.
Topics: Animals; Caffeine; Calcium; Carbachol; Chickens; Dose-Response Relationship, Drug; In Vitro Techniqu | 1984 |
Voltage and receptor mediated contractile activity of colonic smooth muscle in calcium-free solution.
Topics: Animals; Calcium; Carbachol; Cats; Colon; Electric Stimulation; In Vitro Techniques; Muscle Contract | 1984 |
The effect of gallamine, gallopamil and nifedipine on responses to acetylcholine and carbachol in the taenia of the guinea-pig caecum.
Topics: Acetylcholine; Animals; Atropine; Calcium; Carbachol; Cecum; Drug Interactions; Gallamine Triethiodi | 1984 |
Effects of verapamil on histamine-and carbachol-induced contraction of pulmonary tissues in vitro.
Topics: Animals; Carbachol; Dose-Response Relationship, Drug; Female; Guinea Pigs; Histamine Antagonists; In | 1984 |
Schistosoma mansoni: differences in acetylcholine, dopamine, and serotonin control of circular and longitudinal parasite muscles.
Topics: Acetylcholine; Animals; Atropine; Carbachol; Dopamine; Magnesium; Male; Metergoline; Muscle Contract | 1984 |
Endothelium-dependent relaxations of rabbit isolated aorta produced by carbachol and by Ginkgo biloba extract.
Topics: Animals; Antioxidants; Aorta, Thoracic; Atropine; Carbachol; Catechols; Endothelium; In Vitro Techni | 1984 |
[Mechanogram profile of the guinea pig intestine. The refractory phase].
Topics: Animals; Carbachol; Drug Tolerance; Guinea Pigs; Histamine; Intestines; Muscle Contraction; Muscle, | 1984 |
Effects of glucose removal and readmission on potassium contracture in the guinea-pig taenia coli.
Topics: 3-Hydroxybutyric Acid; Adenosine Triphosphate; Animals; Calcium; Carbachol; Female; Glucose; Glycoge | 1984 |
Stimulating and potentiating effects of sodium nitroprusside on the guinea-pig vas deferens and their comparison with the effects on the portal vein and the taenia coli.
Topics: Animals; Carbachol; Colon; Drug Synergism; Ferricyanides; Guinea Pigs; In Vitro Techniques; Male; Me | 1984 |
[The inhibitory cholinergic innervation of the dilator on the movement of the pupil].
Topics: Acetylcholine; Animals; Carbachol; Cattle; Cholinergic Fibers; Dilatation; Electric Stimulation; In | 1984 |
[Propulsive activity of the isolated segmental colon of the guinea pig].
Topics: Animals; Atropine; Carbachol; Colon; Dose-Response Relationship, Drug; Gastrointestinal Motility; Gu | 1984 |
[Drug therapy of detrusor dysfunction].
Topics: Adult; Aged; Carbachol; Dinoprost; Female; Humans; Male; Middle Aged; Muscle Contraction; Muscle, Sm | 1983 |
Comparative effects of beta-agonists on central and peripheral rat airways.
Topics: Animals; Carbachol; Clenbuterol; Ethanolamines; Lung; Male; Metaproterenol; Muscle Contraction; Musc | 1983 |
Pharmacomechanical coupling in smooth muscle may involve phosphatidylinositol metabolism.
Topics: Animals; Carbachol; Diglycerides; Dogs; Membrane Potentials; Muscle Contraction; Muscle, Smooth; Pho | 1984 |
Sensory neural mechanisms in contraction of the rabbit isolated sphincter pupillae: analysis of the responses to capsaicin and electrical field stimulation.
Topics: Animals; Atropine; Capsaicin; Carbachol; Denervation; Dose-Response Relationship, Drug; Electric Sti | 1984 |
Electrical basis of contractions in the muscle layers of the pig colon.
Topics: Animals; Atropine; Carbachol; Colon; Electric Conductivity; Isoproterenol; Muscle Contraction; Muscl | 1983 |
Investigations on unspecific, intestinal elimination in the case of poisoning with psychotropic drugs.
Topics: Animals; Carbachol; Female; Guinea Pigs; Ileum; In Vitro Techniques; Intestinal Mucosa; Intestines; | 1983 |
[Maintenance of the contraction time of the smooth muscle cell].
Topics: Animals; Carbachol; Dose-Response Relationship, Drug; Guinea Pigs; Intestines; Kinetics; Muscle Cont | 1983 |
Phosphorylation of myosin light chain and phosphorylase in tracheal smooth muscle in response to KCl and carbachol.
Topics: Animals; Calcium; Carbachol; Cattle; In Vitro Techniques; Isoproterenol; Kinetics; Membrane Potentia | 1984 |
Changes in sensitivity to the inhibitory effects of adrenergic agonists on intestinal motor activity after chronic sympathetic denervation.
Topics: Acetylcholine; Animals; Carbachol; Clonidine; Gastrointestinal Motility; Guinea Pigs; In Vitro Techn | 1984 |
Affinity of nortriptyline to muscarinic receptors in the bladder and ileum of man and guinea-pig.
Topics: Animals; Bethanechol Compounds; Carbachol; Guinea Pigs; Humans; Ileum; In Vitro Techniques; Male; Mu | 1984 |
Assessment of smooth muscle function in Sesbania drummondii toxicosis in Gallus domesticus.
Topics: Animals; Carbachol; Chickens; Dose-Response Relationship, Drug; Histamine; Ileum; Lung; Muscle Contr | 1984 |
The underlying bases of pharmacological results in agreement or disagreement with the law of initial value.
Topics: Animals; Carbachol; Cattle; Dose-Response Relationship, Drug; Heart Rate; Histamine; In Vitro Techni | 1984 |
Inhibitory effect of acetylcholine on muscular tonus of the small intestine of a lizard.
Topics: Acetylcholine; Acetylcholinesterase; Animals; Carbachol; Esophagus; Intestine, Small; Lizards; Muscl | 1984 |
Comparison of cholinergic activation and desensitization at snake twitch and slow muscle fibre end-plates.
Topics: Action Potentials; Animals; Carbachol; Dose-Response Relationship, Drug; Electric Conductivity; In V | 1984 |
Protease inhibitor homologues from mamba venoms: facilitation of acetylcholine release and interactions with prejunctional blocking toxins.
Topics: Acetylcholine; Animals; Carbachol; Chickens; Elapid Venoms; In Vitro Techniques; Muscle Contraction; | 1982 |
Proposed mechanism of cholinergic action in smooth muscle.
Topics: Animals; Bufo marinus; Calcium; Carbachol; Ion Channels; Muscle Contraction; Muscle, Smooth; Phospha | 1980 |
Metiamide potentiates the stimulant actions of sympathomimetic amines "in vitro".
Topics: Acetylcholine; Animals; Calcium; Carbachol; Dopamine; Drug Synergism; Guinea Pigs; In Vitro Techniqu | 1980 |
Influence of acid-base changes on carbachol- and potassium-induced contractions of taenia coli of the rabbit.
Topics: Acid-Base Equilibrium; Animals; Bicarbonates; Calcium; Carbachol; Carbon Dioxide; Colon; Gastrointes | 1981 |
Myosin phosphorylation and regulation of cross-bridge cycle in tracheal smooth muscle.
Topics: Animals; Carbachol; Kinetics; Male; Muscle Contraction; Muscle, Smooth; Myosins; Phosphorylation; Ra | 1983 |
Carbachol-methohexitone interactions at the chick neuromuscular junction: experiments with the moving fluid electrode technique.
Topics: Acetylcholine; Animals; Animals, Newborn; Carbachol; Chickens; Drug Interactions; Electrodes; In Vit | 1983 |
Spasmolytic activity of the flavonoids from Thymus vulgaris.
Topics: Animals; Barium; Barium Compounds; Carbachol; Chlorides; Flavonoids; Guinea Pigs; Histamine; Ileum; | 1983 |
Impairment and restoration of rat urinary bladder responsiveness following distension.
Topics: Animals; Carbachol; Diabetes Insipidus; Diabetes Mellitus, Experimental; Diuresis; Elasticity; Elect | 1983 |
Muscarinic receptors of rabbit irides.
Topics: Animals; Atropine; Carbachol; Carboxylic Ester Hydrolases; Dose-Response Relationship, Drug; Drug In | 1983 |
Discrimination by dipyridamole of two types of responses to adenosine and ATP of the carbachol-induced contraction of guinea-pig trachea.
Topics: Adenosine; Adenosine Triphosphate; Animals; Carbachol; Dipyridamole; Female; Glucose; Guinea Pigs; I | 1983 |
Topographical differences in the physiological response of canine airway smooth muscle.
Topics: Animals; Bronchi; Carbachol; Dogs; Histamine; Male; Membrane Potentials; Muscle Contraction; Muscle, | 1983 |
[The contraction curve of the isolated intestine produced by medium-high doses of drugs. The depressive effects of sodium].
Topics: Animals; Atropine; Calcium; Carbachol; Guinea Pigs; Ileum; Muscle Contraction; Sodium; Time Factors | 1983 |
Potentiating effects of high concentration of sodium nitroprusside on the contraction of guinea-pig vas deferens.
Topics: Animals; Carbachol; Drug Synergism; Ferricyanides; Guinea Pigs; Male; Muscle Contraction; Nitropruss | 1983 |
The selective antimuscarinic action of stercuronium.
Topics: Alkaloids; Animals; Carbachol; Drug Interactions; Gallamine Triethiodide; Guinea Pigs; In Vitro Tech | 1980 |
Effect of antimuscarinic agents on the contractile responses to cholinomimetics in the rat anococcygeus muscle.
Topics: Animals; Atropine; Carbachol; Hexamethonium Compounds; In Vitro Techniques; Male; Methacholine Compo | 1981 |
Enhancement of isolated airway responses to bronchoconstrictive agonists by the slow-reacting substance of anaphylaxis antagonist FPL 55712.
Topics: Animals; Arachidonic Acids; Carbachol; Chromones; Ethers; Guinea Pigs; Histamine; In Vitro Technique | 1981 |
Inhibitory effect of bassianolide, a cyclodepsipeptide, on drug-induced contractions of isolated smooth muscle preparations.
Topics: Acetylcholine; Animals; Carbachol; Dinoprostone; Guinea Pigs; Histamine Antagonists; Ileum; In Vitro | 1982 |
Studies on spontaneous contractions of chick biventer cervicis muscles induced by cadmium ion.
Topics: Acetylcholine; Animals; Cadmium; Calcium; Carbachol; Chickens; Female; Guinea Pigs; In Vitro Techniq | 1982 |
Effects of vaccination with Haemophilus influenzae on adrenoceptor function of tracheal and parenchymal strips.
Topics: Animals; Asthma; Bacterial Vaccines; Carbachol; Guinea Pigs; Haemophilus Infections; Haemophilus inf | 1980 |
Pharmacological responses of human and porcine lung parenchyma, bronchus and pulmonary artery.
Topics: Animals; Bronchi; Carbachol; Dimethylphenylpiperazinium Iodide; Humans; In Vitro Techniques; Lung; M | 1982 |
Evidence for a prostaglandin link in the purinergic activation of rabbit bladder smooth muscle.
Topics: Adenosine Triphosphate; Animals; Calcium; Carbachol; In Vitro Techniques; Indomethacin; Muscle Contr | 1982 |
Inhibition of bronchoconstriction in the guinea pig by a calcium channel blocker, nifedipine.
Topics: Animals; Bronchi; Carbachol; Dose-Response Relationship, Drug; Guinea Pigs; Histamine; In Vitro Tech | 1982 |
The inhibitory action of acetaldehyde on the tonic component of the potassium-induced contracture in the guinea-pig taenia caeci.
Topics: Acetaldehyde; Animals; Calcium; Carbachol; Cecum; Electric Stimulation; Guinea Pigs; In Vitro Techni | 1982 |
Spare cholinergic receptors in the urinary bladder.
Topics: Animals; Binding, Competitive; Calcium; Carbachol; Kinetics; Lanthanum; Male; Muscle Contraction; Mu | 1982 |
The effects of nifedipine and verapamil on spontaneous and carbachol-stimulated contractions of rat urinary bladder "in vivo".
Topics: Animals; Carbachol; Drug Interactions; Male; Muscle Contraction; Muscle, Smooth; Nifedipine; Pyridin | 1982 |
Effects of clozapine in a selective muscarinic bioassay and on single cells of the rat hippocampus.
Topics: Acetylcholine; Animals; Astacoidea; Atropine; Carbachol; Cats; Clozapine; Dibenzazepines; Drug Inter | 1982 |
Influence of N-ethylmaleimide on cholinoceptors and responses in longitudinal muscles from guinea-pig ileum.
Topics: Acetylcholine; Alkylation; Animals; Barium; Carbachol; Ethylmaleimide; Guinea Pigs; Ileum; In Vitro | 1982 |
Effects of pentagastrin, histamine, carbamylcholine and catecholamines on gastric secretion, motility and emptying in the rat.
Topics: Animals; Carbachol; Catecholamines; Dose-Response Relationship, Drug; Gastric Emptying; Gastric Juic | 1982 |
The potentiating action of acetylcholine on the chemosensitivity of denervated skeletal muscle.
Topics: Acetylcholine; Animals; Bungarotoxins; Carbachol; Drug Synergism; Electric Conductivity; Female; Iod | 1982 |
Differential effect of verapamil on noradrenaline, carbachol, tyramine and 5-hydroxytryptamine induced contractions of the rat anococcygeus muscle.
Topics: Animals; Calcium; Carbachol; Dantrolene; Drug Interactions; In Vitro Techniques; Male; Muscle Contra | 1982 |
Reactivity of airway smooth muscles to bronchoactive agents in langur monkeys.
Topics: Animals; Bronchi; Carbachol; Cercopithecidae; Dose-Response Relationship, Drug; Female; Histamine; I | 1981 |
Effects of tartrazine of different contractile stimuli in guinea pig tracheal muscle.
Topics: Animals; Arachidonic Acids; Azo Compounds; Carbachol; Guinea Pigs; Histamine Antagonists; Indomethac | 1981 |
A method for culturing canine tracheal smooth muscle cells in vitro: morphologic and pharmacologic observations.
Topics: Animals; Carbachol; Culture Techniques; Dogs; Female; Hydrogen-Ion Concentration; Male; Microscopy, | 1981 |
Influence of castration upon the seminal vesicle response to parasympathomimetic drugs.
Topics: Acetylcholine; Animals; Bethanechol Compounds; Carbachol; Castration; In Vitro Techniques; Male; Mus | 1981 |
Adaptation of the neuromuscular junction to chronic acetylcholinesterase inhibition due to phospholine treatment.
Topics: Animals; Carbachol; Cholinesterase Inhibitors; Diaphragm; Echothiophate Iodide; In Vitro Techniques; | 1981 |
Influence of tracheal contraction on relaxant effects in vitro of theophylline and isoprenaline.
Topics: Airway Resistance; Animals; Carbachol; Drug Interactions; Female; Guinea Pigs; Hydrogen-Ion Concentr | 1981 |
The response of the rabbit rectococcygeus muscle to stimulation of extrinsic inhibitory nerves and to sympathomimetic drugs.
Topics: Acetylcholine; Animals; Carbachol; Electric Stimulation; Intestines; Muscle Contraction; Muscle, Smo | 1981 |
On the adrenergic system of ganoid fish: the Florida spotted gar, Lepisosteus platyrhincus (Holostei).
Topics: Adrenergic Fibers; Animals; Carbachol; Catecholamines; Chromaffin System; Fishes; Fluorescence; Hist | 1981 |
Cholinergic responses in different sections of rat airways.
Topics: Acetylcholine; Animals; Atropine; Carbachol; Dose-Response Relationship, Drug; Lung; Male; Muscle Co | 1981 |
Relaxation of the rabbit colon on pelvic nerve stimulation.
Topics: Animals; Carbachol; Colon; Electric Stimulation; Female; In Vitro Techniques; Male; Muscle Contracti | 1981 |
Effects of histamine, high potassium and carbachol on 42K efflux from longitudinal muscle of guinea-pig intestine.
Topics: Animals; Atropine; Carbachol; Guinea Pigs; Histamine; Ileum; In Vitro Techniques; Muscle Contraction | 1981 |
Actions of chloroquine and its N-oxidation metabolites on the rectus abdominis muscle of the toad (Bufo regularis).
Topics: Acetylcholine; Animals; Biotransformation; Bufonidae; Carbachol; Chloroquine; Cyclic N-Oxides; In Vi | 1981 |
Ethanol potentiation of choline, acetylcholine, carbachol and phenyltrimethylammonium contractions in the chick biventer cervicis muscle.
Topics: Acetylcholine; Animals; Carbachol; Chickens; Choline; Dose-Response Relationship, Drug; Drug Synergi | 1980 |
Schistosoma mansoni: characterization of the electrical potential from the tegument of adult males.
Topics: Animals; Calcium; Carbachol; Dopamine; Electric Conductivity; Male; Membrane Potentials; Microelectr | 1980 |
A comparison of effects evoked in guinea-pig taenia caecum by purine nucleotides and by "purinergic" nerve stimulation.
Topics: Adenine Nucleotides; Adenosine; Animals; Carbachol; Cecum; Female; Guinea Pigs; In Vitro Techniques; | 1980 |
Anticholinergic and calcium antagonistic effects of terodiline in rabbit urinary bladder.
Topics: Animals; Atropine; Butylamines; Calcium; Carbachol; Dose-Response Relationship, Drug; Female; Male; | 1980 |
Drug-induced effects on the longitudinal smooth muscle of rat bronchus.
Topics: Animals; Bradykinin; Bronchi; Carbachol; Male; Muscle Contraction; Muscle, Smooth; Potassium Chlorid | 1980 |
Further studies of dog tracheobronchial smooth muscle.
Topics: Airway Resistance; Animals; Bronchi; Carbachol; Dogs; Drug Interactions; Histamine; Histamine Antago | 1980 |
Bovine lung parenchyma strip has both airway and vascular characteristics. (Pharmacological comparisons with bronchus, pulmonary artery and vein).
Topics: Animals; Bronchi; Carbachol; Cattle; Epinephrine; Female; Histamine; In Vitro Techniques; Lung; Male | 1980 |
The effect of imipramine on rat detrusor muscle contractility.
Topics: Animals; Atropine; Calcium; Carbachol; Drug Interactions; Imipramine; In Vitro Techniques; Muscle Co | 1980 |
Evidence for multiple sources of calcium for activation of the contractile mechanism of guinea-pig taenia coli on stimulation with carbachol.
Topics: Animals; Calcium; Carbachol; Colon; Gallopamil; Guinea Pigs; In Vitro Techniques; Manganese; Muscle | 1980 |
Mechanisms of the responses to non-cholinergic, non-adrenergic nerve stimulation and to ATP in isolated rabbit urinary bladder: evidence for ADP evoked prostaglandin release.
Topics: Adenine Nucleotides; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Calcium; Carbachol; Ele | 1980 |
Contribution of prostaglandins to the adenosine triphosphate-induced contraction of rabbit urinary bladder.
Topics: Adenosine Triphosphate; Animals; Carbachol; Drug Interactions; Electric Stimulation; Guinea Pigs; In | 1980 |
Reactivity of trachea, bronchi, and lung strips to histamine and carbachol in rhesus monkeys.
Topics: Animals; Bronchi; Carbachol; Dose-Response Relationship, Drug; Female; Histamine; In Vitro Technique | 1980 |
The effect of sodium removal on the contractile response of the guinea-pig taenia coli to carbachol.
Topics: Animals; Biological Transport, Active; Calcium; Carbachol; Colon; Guinea Pigs; In Vitro Techniques; | 1980 |
The interaction of amine local anaesthetics with muscarinic receptors.
Topics: Amines; Anesthetics, Local; Animals; Brain; Carbachol; Guinea Pigs; In Vitro Techniques; Membranes; | 1980 |
A selective Ascaris acetylcholine receptor antagonist: 1,1-dimethyl-4-(2-quinolyl)-piperazinium iodide.
Topics: Animals; Ascaris; Carbachol; Cholinergic Antagonists; Dimethylphenylpiperazinium Iodide; Female; Gan | 1995 |
Effect of magnesium ions on rabbit detrusor contractility and intracellular free calcium.
Topics: Animals; Calcium; Carbachol; Electric Stimulation; Fura-2; In Vitro Techniques; Magnesium; Male; Mus | 1995 |
Serotonin and acetylcholine: further analysis of praziquantel-induced contraction of magnesium-paralysed Schistosoma mansoni.
Topics: 1-Methyl-3-isobutylxanthine; 4-Aminopyridine; Amifampridine; Animals; Arecoline; Carbachol; Colforsi | 1993 |
Identification of PDE isozymes in human pulmonary artery and effect of selective PDE inhibitors.
Topics: 1-Methyl-3-isobutylxanthine; Adult; Aged; Antihypertensive Agents; Carbachol; Colforsin; Cytosol; Di | 1994 |
Synthesis and muscarinic receptors affinity of a series of antagonist bivalent ligands.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Animals; Atrial Function; Carb | 1994 |
Epithelium modulates the kinetics of the response to substance P and its intrinsic activity in the guinea-pig trachea.
Topics: Animals; Carbachol; Epithelium; Guinea Pigs; Histamine; In Vitro Techniques; Kinetics; Male; Muscle | 1994 |
The contractile response of thiopental in large and small ovine airways.
Topics: Animals; Atropine; Bronchi; Bronchoconstriction; Carbachol; Cell Degranulation; Dexamethasone; Dose- | 1994 |
Recombinant stem cell factor-induced mast cell activation and smooth muscle contraction in human bronchi.
Topics: Antibodies, Anti-Idiotypic; Autacoids; Bronchi; Carbachol; Dicarboxylic Acids; Hematopoietic Cell Gr | 1994 |
Interaction of galanin fragments with galanin receptors on isolated smooth muscle cells from guinea pig stomach: identification of a novel galanin receptor subtype.
Topics: Animals; Carbachol; Cyclic AMP; Galanin; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; | 1995 |
Pathways involved in muscarinic M1 and M2 receptor stimulation in rabbit vas deferens.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Adenylyl Cyclase Inhibitors; A | 1994 |
Antagonistic properties of McNeil-A-343 at 5-HT4 and 5-HT3 receptors.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Animals; Carbachol; Dose-Respo | 1994 |
Tachykinins contract trachea from Fischer 344 rats by interaction with a tachykinin NK1 receptor.
Topics: Animals; Carbachol; In Vitro Techniques; Isometric Contraction; Muscle Contraction; Muscle, Smooth; | 1994 |
Galanin-induced relaxation in gastric smooth muscle cells is mediated by cyclic AMP.
Topics: Animals; Carbachol; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Dr | 1994 |
Functional evidence for a glibenclamide-sensitive K+ channel in rat ileal smooth muscle.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1994 |
Effect of temperature on muscarinic cholinoceptor-mediated phosphoinositide metabolism and tension generation in bovine tracheal smooth muscle.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Animals; Carbachol; Cattle; Co | 1994 |
Characterization of muscarinic receptors mediating relaxation and contraction in the rat iris dilator muscle.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Acetylcholine; Alkaloids; Anim | 1995 |
Effects of magnesium ions on detrusor contraction in rat.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1995 |
Interaction between atrial natriuretic peptide and vasoactive intestinal peptide in guinea pig cecal smooth muscle.
Topics: Animals; Atrial Natriuretic Factor; Carbachol; Cecum; Cells, Cultured; Gastrointestinal Motility; Gu | 1995 |
Effect of omega-conotoxin GVIA on tetrodotoxin-insensitive acetylcholine release by nicotine in guinea-pig bladder.
Topics: Acetylcholine; Animals; Calcium; Calcium Channel Blockers; Carbachol; Electric Stimulation; Female; | 1995 |
Necessity of newly synthesized ATP by creatine kinase for contraction of permeabilized longitudinal muscle preparations of rat proximal colon.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Calcium; Carbachol; Cell Membrane Permeabili | 1995 |
Effect of the potassium channel opener YM934 on the contractile response to electrical field stimulation in pig detrusor smooth muscle.
Topics: Adenosine Triphosphate; Animals; Atropine; Benzoxazines; Carbachol; Cholinergic Antagonists; Cyclic | 1995 |
Length density and total length of acetylcholinesterase positive nerves related to cystometry and in vitro studies of muscle strips in mini-pig urinary bladder after chronic outflow obstruction and recovery from obstruction.
Topics: Acetylcholinesterase; Animals; Carbachol; Cholinergic Fibers; Chronic Disease; Electric Stimulation; | 1995 |
Endothelin-1 receptor density, distribution, and function in human isolated asthmatic airways.
Topics: Adolescent; Adult; Asthma; Autoradiography; Bronchi; Carbachol; Dose-Response Relationship, Drug; En | 1995 |
Vascular reactivity in alcoholic rat aortas: in vitro interactions between catecholamines and alcohol.
Topics: Alcoholism; Animals; Aorta; Carbachol; Diabetes Mellitus, Experimental; Disease Models, Animal; Dose | 1995 |
Sustained contraction produced by caffeine after ryanodine treatment in the circular muscle of the guinea-pig gastric antrum and rabbit portal vein.
Topics: Animals; Caffeine; Calcium; Carbachol; Colforsin; Female; Fura-2; Guinea Pigs; Indomethacin; Male; M | 1995 |
The effect of hormones and peptides involved in water balance on rat colonic motility in vitro.
Topics: Aldosterone; Angiotensin II; Animals; Arginine; Arginine Vasopressin; Carbachol; Colon; Electric Sti | 1995 |
Airways of a hyperresponsive rat strain show decreased relaxant responses to sodium nitroprusside.
Topics: Animals; Carbachol; Cyclic GMP; In Vitro Techniques; Male; Methacholine Chloride; Muscle Contraction | 1995 |
Inhibitory actions of GABA on rabbit urinary bladder muscle strips: mediation by potassium channels.
Topics: Animals; Baclofen; Carbachol; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Muscle Contraction | 1995 |
Phasic contractions of the muscular components of human esophagus and gastroesophageal junction in vitro.
Topics: Adult; Aged; Aged, 80 and over; Atropine; Carbachol; Electrophysiology; Esophagogastric Junction; Es | 1995 |
Effect of nitric oxide on in vitro responsiveness of bovine bronchus and pulmonary vessels.
Topics: Animals; Bronchi; Carbachol; Cattle; Cell Hypoxia; Dose-Response Relationship, Drug; Hemoglobins; In | 1995 |
Characterization of cholecystokinin receptors on the human gallbladder.
Topics: Autoradiography; Benzodiazepinones; Binding Sites; Carbachol; Devazepide; Dose-Response Relationship | 1993 |
Evaluation of the relaxant effects of SCA40, a novel charybdotoxin-sensitive potassium channel opener, in guinea-pig isolated trachealis.
Topics: Animals; Carbachol; Charybdotoxin; Glyburide; Guinea Pigs; Imidazoles; In Vitro Techniques; Isoprote | 1993 |
Regulation of tone in pig urethral smooth muscle.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Atropine; Carbachol; Electric Stimulation; Female; Gu | 1993 |
Tachykinins contract the circular muscle of the human esophageal body in vitro via NK2 receptors.
Topics: Adolescent; Adult; Aged; Atropine; Benzamides; Biphenyl Compounds; Carbachol; Dose-Response Relation | 1993 |
Effect of thiazide diuretics against neurally mediated contraction of guinea pig airways. Contribution of carbonic anhydrase.
Topics: Acetylcholine; Animals; Benzothiadiazines; Bronchi; Carbachol; Carbonic Anhydrase Inhibitors; Carbon | 1993 |
Different mechanism of tachykinin NK2 receptor blockade by SR 48968 and MEN 10,627 in the guinea-pig isolated gallbladder and colon.
Topics: Amino Acid Sequence; Animals; Benzamides; Binding, Competitive; Carbachol; Colon; Gallbladder; Guine | 1994 |
The effect of muscarinic agonists and selective receptor subtype antagonists on the contractile response of the isolated rhesus monkey ciliary muscle.
Topics: Animals; Carbachol; Ciliary Body; Dose-Response Relationship, Drug; In Vitro Techniques; Macaca mula | 1994 |
Physiological and morphometric studies into the pathophysiology of detrusor hyperreflexia in neuropathic patients.
Topics: Adult; Carbachol; Dose-Response Relationship, Drug; Electric Stimulation; Female; Humans; In Vitro T | 1995 |
The effects of five phospholipases A2 from the venom of king brown snake, Pseudechis australis, on nerve and muscle.
Topics: Acetylcholine; Action Potentials; Animals; Carbachol; Chickens; Diaphragm; Dose-Response Relationshi | 1994 |
Characterization of ciliary muscle relaxation induced by various agents in cats.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Carbachol; Cats; Ciliary Body; Cyclic AMP; Mus | 1995 |
Interactions between prostaglandins, muscarinic agonists and the adenylate cyclase and phospholipase C systems in dog ciliary smooth muscle.
Topics: Adenylyl Cyclases; Animals; Carbachol; Ciliary Body; Cyclic AMP; Dinoprostone; Dogs; Indomethacin; I | 1995 |
Effects of divalent cations and La3+ on contractility and ecto-ATPase activity in the guinea-pig urinary bladder.
Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Carbachol; Cations, Divalent; Chlorides; | 1995 |
Possible involvement of a small G-protein sensitive to exoenzyme C3 of Clostridium botulinum in the regulation of myofilament Ca2+ sensitivity in beta-escin skinned smooth muscle of guinea pig ileum.
Topics: Animals; Calcium; Carbachol; Complement C3; GTP-Binding Proteins; Guanosine Triphosphate; Guinea Pig | 1995 |
Effects of gabexate, a protease inhibitor, on smooth muscle of guinea-pig stomach fundus.
Topics: Animals; Carbachol; Cholinesterase Inhibitors; Female; Gabexate; Gastric Fundus; Guinea Pigs; Male; | 1995 |
Porcine detrusor cyclic nucleotide phosphodiesterase isoenzymes: characterization and functional effects of various phosphodiesterase inhibitors in vitro.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Calmodulin; Carba | 1995 |
Determinants of airway smooth muscle shortening in excised canine lobes.
Topics: Airway Resistance; Animals; Carbachol; Dogs; In Vitro Techniques; Lung; Lung Volume Measurements; Mu | 1995 |
Role of 1,2-sn diacylglycerol in airway smooth muscle stimulated by carbachol.
Topics: Adenylyl Cyclases; Animals; Carbachol; Cattle; Diglycerides; Dose-Response Relationship, Drug; In Vi | 1995 |
Magnesium and lithium antagonism of carbachol- and electrically-induced smooth muscle contractions in the rat gastrointestinal tract.
Topics: Animals; Calcium; Calcium Channels; Carbachol; Cell Membrane Permeability; Colon; Digestive System; | 1994 |
Effect of trimebutine on contractile responses in skinned ileal smooth muscle.
Topics: Animals; Caffeine; Calcimycin; Calcium; Carbachol; Dose-Response Relationship, Drug; Drug Interactio | 1994 |
Mechanosensitive modulation of myosin phosphorylation and phosphatidylinositol turnover in smooth muscle.
Topics: Animals; Calcium; Carbachol; Cattle; Lithium Chloride; Muscle Contraction; Muscle, Smooth; Myosins; | 1994 |
Pharmacological characteristics of liriodenine, isolated from Fissistigma glaucescens, a novel muscarinic receptor antagonist in guinea-pigs.
Topics: Animals; Aporphines; Carbachol; Cyclic AMP; Cyclic GMP; Female; Guinea Pigs; Heart Atria; Ileum; In | 1994 |
Somatostatin-induced inhibition of neurotransmission in the mouse isolated vas deferens is resistant to pertussis toxin.
Topics: Amino Acid Sequence; Animals; Carbachol; Heart Atria; Heart Rate; In Vitro Techniques; Male; Mice; M | 1994 |
Endothelin ETB receptor antagonist, RES-701-1: effects on isolated blood vessels and small intestine.
Topics: Amino Acid Sequence; Animals; Aorta, Thoracic; Carbachol; Dose-Response Relationship, Drug; Electrop | 1994 |
5-Hydroxytryptamine2B receptor signaling in rat stomach fundus: role of voltage-dependent calcium channels, intracellular calcium release and protein kinase C.
Topics: Animals; Caffeine; Calcium; Calcium Channels; Carbachol; Gastrointestinal Motility; In Vitro Techniq | 1995 |
The effects of aldose reductase inhibition with ponalrestat on changes in vascular function in streptozotocin diabetic rats.
Topics: Aldehyde Reductase; Animals; Aorta, Thoracic; Carbachol; Colforsin; Diabetes Mellitus, Experimental; | 1994 |
The role of extracellular Ca2+ in carbachol-induced tonic contraction of the pig detrusor smooth muscle.
Topics: Animals; Atropine; Benzoxazines; Calcium; Carbachol; Cyclic N-Oxides; Dose-Response Relationship, Dr | 1994 |
The actions of extracellular H+ on the electrophysiological properties of isolated human detrusor smooth muscle cells.
Topics: Acidosis; Action Potentials; Calcium; Calcium Channels; Carbachol; Carbon Dioxide; Electrophysiology | 1994 |
The potentiation of carbachol-induced transient contractions in guinea-pig stomach muscles by a low temperature.
Topics: Animals; Calcium; Carbachol; Cold Temperature; Dose-Response Relationship, Drug; Female; Guinea Pigs | 1994 |
5-HT4 receptors in rat but not guinea pig, rabbit or dog esophageal smooth muscle.
Topics: Animals; Carbachol; Dogs; Esophagus; Female; Male; Muscle Contraction; Muscle, Smooth; Rabbits; Rats | 1994 |
Antimuscarinic action of liriodenine, isolated from Fissistigma glaucescens, in canine tracheal smooth muscle.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Antineoplastic Agents, Phytogenic; Aporphin | 1994 |
Variable potency of nitrergic-nitrovasodilator relaxations of the mouse anococcygeus against different forms of induced tone.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Anti-Arrhythmia Agents; | 1994 |
Airway smooth muscle relaxant effects of the cocaine pyrolysis product, methylecgonidine.
Topics: Acetylcholine; Animals; Bronchodilator Agents; Carbachol; Chickens; Cocaine; Guinea Pigs; Histamine; | 1995 |
Mechanisms of cyclic nucleotide-induced relaxation in canine tracheal smooth muscle.
Topics: Adenylyl Cyclases; Animals; Calcium Channels; Calcium-Transporting ATPases; Carbachol; Colforsin; Cy | 1995 |
Effect of neurotensin on the canine gallbladder motility: in vivo and in vitro experiments.
Topics: Acetylcholine; Animals; Atropine; Carbachol; Dogs; Gallbladder; Guinea Pigs; Hexamethonium; Hexameth | 1993 |
Raphe pallidus stimulation increases gastric contractility via TRH projections to the dorsal vagal complex in rats.
Topics: Animals; Carbachol; Dose-Response Relationship, Drug; Gastrointestinal Motility; Globus Pallidus; Gl | 1994 |
Influence of epithelial removal on the antihistaminic activity of azelastine in the guinea-pig airway smooth muscles.
Topics: Animals; Bronchi; Carbachol; Epithelium; Guinea Pigs; Histamine; Histamine H1 Antagonists; In Vitro | 1993 |
Predominance of endothelinA (ETA) receptors in ovine airway smooth muscle and their mediation of ET-1-induced contraction.
Topics: Animals; Autoradiography; Carbachol; Endothelin Receptor Antagonists; Endothelins; In Vitro Techniqu | 1994 |
All-or-nothing responses to carbachol in single intestinal smooth muscle cells of rat.
Topics: Animals; Calcium; Carbachol; Cell Membrane; Cytosol; Electrophysiology; In Vitro Techniques; Intesti | 1994 |
[Effects of gamma interferon (IFN-gamma) and interleukin-1 beta (IL-1 beta) on contractile and relaxing responses of guinea-pig airway strips].
Topics: Animals; Carbachol; Dose-Response Relationship, Drug; Guinea Pigs; In Vitro Techniques; Interferon-g | 1994 |
Non-adrenergic non-cholinergic (NANC) excitatory response of the channel catfish intestine.
Topics: Acetylcholine; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Atropine; Autonom | 1994 |
Acute ethanol inhibits calcium influxes into esophageal smooth but not striated muscle: a possible mechanism for ethanol-induced inhibition of esophageal contractility.
Topics: Animals; Biological Transport; Calcium; Carbachol; Cats; Esophagus; Ethanol; Female; Homeostasis; In | 1994 |
Regulation of PI hydrolysis and cAMP formation by muscarinic M3 receptor in guinea pig gallbladder.
Topics: Animals; Carbachol; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Gallbladder; Guinea Pig | 1994 |
Selective desensitization of 5-hydroxytryptamine 2A receptor mediated contraction in guinea pig trachea.
Topics: Animals; Carbachol; Guinea Pigs; In Vitro Techniques; Kinetics; Male; Muscle Contraction; Muscle, Sm | 1994 |
Contractile serotonin-2A receptor signal transduction in guinea pig trachea: importance of protein kinase C and extracellular and intracellular calcium but not phosphoinositide hydrolysis.
Topics: Alkaloids; Animals; Calcium; Calcium Channels; Carbachol; Guinea Pigs; Hydrolysis; In Vitro Techniqu | 1994 |
Unknown effects of clinically used drugs as bias in clinical trials: antihistaminergic activity of the antihypertensive fixed-dose combination Betathiazid.
Topics: Animals; Antihypertensive Agents; Carbachol; Drug Combinations; Guinea Pigs; Histamine; Histamine H1 | 1994 |
Differences in relaxant effects of cyclic GMP on skinned muscle preparations from the proximal and distal colon of rats.
Topics: Animals; Autonomic Nervous System; Calcium; Capillary Permeability; Carbachol; Colon; Cyclic GMP; Ma | 1994 |
New classes of antimuscarinic agents endowed with selective antispasmodic properties. 1-Arylsulfonyl pyrrolidin-2-ones and 2-thiones, 1-arylsulfonyl piperidin-2-ones and 2-thiones and 1-arylsulfonyl hexahydro-2H-azepin-2-one.
Topics: Animals; Arecoline; Atropine; Azepines; Butylscopolammonium Bromide; Carbachol; Gastric Acid; Gastro | 1994 |
Modulation by the endothelium of sympathetic vasoconstriction in an in vitro preparation of the rat tail artery.
Topics: Angiotensin II; Animals; Arginine; Arteries; Carbachol; Electric Stimulation; Endothelium, Vascular; | 1994 |
Modulation of urinary bladder function by sex hormones in streptozotocin-diabetic rats.
Topics: Adenosine Triphosphate; Animals; Body Weight; Carbachol; Castration; Diabetes Mellitus, Experimental | 1994 |
The use of the chick biventer cervicis preparation to assess the protective activity of six international reference antivenoms on the neuromuscular effects of snake venoms in vitro.
Topics: Acetylcholine; Animals; Antivenins; Carbachol; Chickens; Drug Interactions; Muscle Contraction; Musc | 1994 |
Investigation of the actions of PPADS, a novel P2x-purinoceptor antagonist, in the guinea-pig isolated vas deferens.
Topics: Adenosine Triphosphate; Animals; Carbachol; Electric Stimulation; Electrophysiology; Guinea Pigs; Hi | 1994 |
Prolonged in vivo administration of cyclosporine causes enteric smooth muscle hyperplasia in normal rat intestine and small bowel grafts.
Topics: Animals; Carbachol; Cell Division; Cyclosporine; Hyperplasia; Intestine, Small; Muscle Contraction; | 1994 |
Effects of cyclopiazonic acid on [Ca2+]i and contraction in rat urinary bladder smooth muscle.
Topics: Animals; Calcium; Carbachol; In Vitro Techniques; Indoles; Male; Muscle Contraction; Muscle, Smooth; | 1994 |
Structure and mechanics of growing arterial microvessels from hypertrophied urinary bladder in the rat.
Topics: Animals; Arterioles; Carbachol; Female; Histocytochemistry; Hypertrophy; Microscopy, Electron; Muscl | 1994 |
Bronchial smooth muscle energetics: effect of iodoacetate and hypoxia.
Topics: Animals; Bronchi; Carbachol; Cattle; Energy Metabolism; Hypoxia; In Vitro Techniques; Iodoacetates; | 1994 |
Expression of dihydropyridine resistance differs in porcine bronchial and tracheal smooth muscle.
Topics: Animals; Bronchi; Cadmium; Carbachol; Dose-Response Relationship, Drug; Drug Resistance; Female; Mal | 1994 |
Human airway smooth muscle responsiveness in neonatal lung specimens.
Topics: Carbachol; Female; Histamine; Humans; Infant, Newborn; Lung; Male; Muscle Contraction; Muscle, Smoot | 1994 |
Inhibitory effects of dantrolene on contractile responses in gastric smooth muscle of the rat.
Topics: Animals; Caffeine; Calcium; Carbachol; Dantrolene; Dose-Response Relationship, Drug; In Vitro Techni | 1994 |
Age-related alterations in sensitivity of muscarinic and serotonergic responses of guinea pig trachea to removal of extracellular Ca2+.
Topics: Aging; Animals; Calcium; Carbachol; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Musc | 1994 |
Effects of m-cholinoceptor antagonists on the neuromuscular junction.
Topics: Abdominal Muscles; Animals; Aorta, Thoracic; Calcium; Carbachol; Cholinergic Antagonists; Diaphragm; | 1994 |
Age does not affect contractile responses of the isolated rhesus monkey ciliary muscle to muscarinic agonists.
Topics: Aging; Animals; Atropine; Carbachol; Cells, Cultured; Ciliary Body; Culture Media; Ganglionic Stimul | 1993 |
Phosphorylation-contraction coupling in smooth muscle: role of caldesmon.
Topics: Animals; Calmodulin-Binding Proteins; Carbachol; Chickens; Gizzard, Avian; Muscle Contraction; Muscl | 1993 |
Mechanism of the contractile response to platelet-activating factor (PAF) of the rat stomach fundus. II. PAF-induced phosphatidylinositol turnover and desensitization.
Topics: Animals; Carbachol; Gastric Fundus; Hydrolysis; In Vitro Techniques; Male; Muscle Contraction; Muscl | 1993 |
Responses of the human neurogenic bladder to KCl, carbachol, ATP and CaCl2.
Topics: Adenosine Triphosphate; Calcium Chloride; Carbachol; Humans; Muscle Contraction; Potassium Chloride; | 1994 |
Inhibitory effects of propiverine on rat and guinea-pig urinary bladder muscle.
Topics: Animals; Atropine; Benzilates; Calcium Channel Blockers; Calcium Channels; Carbachol; Female; Guinea | 1993 |
Thromboxane-like actions of prostaglandin D2 on the contractility of the rat colon in vitro.
Topics: Animals; Carbachol; Colon; Eicosanoids; Female; In Vitro Techniques; Isometric Contraction; Muscle C | 1994 |
Gamma-interferon modifies guinea pig airway functions in vitro.
Topics: Animals; Arginine; Carbachol; Cycloheximide; Guinea Pigs; In Vitro Techniques; Indomethacin; Interfe | 1994 |
Non-adrenergic non-cholinergic inhibitory innervation shown by electrical field stimulation of isolated strips of human gall bladder muscle.
Topics: Atropine; Carbachol; Ceruletide; Cholecystokinin; Electric Stimulation; Gallbladder; Histamine; Huma | 1994 |
Inhibition in the human urinary bladder by gamma-amino-butyric acid.
Topics: Aged; Carbachol; Culture Techniques; Dose-Response Relationship, Drug; Electric Stimulation; Female; | 1994 |
Schistosoma mansoni: myogenic characteristics of phorbol ester-induced muscle contraction.
Topics: Acetylcholine; Animals; Cadmium; Calcimycin; Calcium; Calcium Channels; Carbachol; Cell Membrane Per | 1994 |
Studies on the properties of myo-inositol-1,4,5-trisphosphate 5-phosphatase and myo-inositol monophosphatase in bovine iris sphincter smooth muscle: effects of okadaic acid and protein phosphorylation.
Topics: Animals; Carbachol; Cattle; Disulfiram; Enzyme Activation; Ethers, Cyclic; Hydrogen-Ion Concentratio | 1994 |
Characterization of muscarinic receptor involvement in human ciliary muscle cell function.
Topics: Atropine; Carbachol; Cells, Cultured; Ciliary Body; Dose-Response Relationship, Drug; Enzyme Activat | 1994 |
M3 muscarinic receptors mediate an increase in both inositol trisphosphate production and cyclic AMP formation in dog iris sphincter smooth muscle.
Topics: Adenylyl Cyclases; Animals; Calcium; Calcium Channel Blockers; Carbachol; Cyclic AMP; Dogs; Inositol | 1994 |
Fentanyl and pethidine are antagonists on muscarinic receptors in guinea-pig ileum.
Topics: Animals; Binding, Competitive; Carbachol; Dose-Response Relationship, Drug; Fentanyl; Guinea Pigs; I | 1993 |
Autoradiographic demonstration of the distribution of diacylglycerol in the gastric muscularis muscle of Bufo marinus: is diacylglycerol one of the second messengers in the muscularis muscle?
Topics: Acetylcholine; Animals; Autoradiography; Bufo marinus; Carbachol; Diglycerides; Gastrointestinal Mot | 1993 |
Partial inhibition by epithelium of tracheal smooth muscle relaxation induced by the potassium channel activator, BRL 38227.
Topics: Aminophylline; Animals; Benzopyrans; Biotransformation; Bronchodilator Agents; Carbachol; Cromakalim | 1993 |
Endothelin-1 (ET-1)-induced contraction in rat isolated trachea: involvement of ETA and ETB receptors and multiple signal transduction systems.
Topics: Animals; Autoradiography; Carbachol; Endothelin Receptor Antagonists; Endothelins; In Vitro Techniqu | 1993 |
Response of the human neurogenic bladder to KCl, carbachol, ATP and CaCl2.
Topics: Adenosine Triphosphate; Adolescent; Adult; Calcium Chloride; Carbachol; Child; Child, Preschool; Cul | 1993 |
The effect of serotonin on the rabbit isolated iris sphincter muscle.
Topics: Animals; Carbachol; Dose-Response Relationship, Drug; Iris; Muscle Contraction; Muscle Relaxation; M | 1993 |
Characterization of muscarinic receptors on guinea pig gallbladder smooth muscle.
Topics: Animals; Autoradiography; Carbachol; Gallbladder; Guinea Pigs; In Vitro Techniques; Male; Muscle Con | 1993 |
Mechanical properties of isolated smooth muscle from human rectum and internal anal sphincter.
Topics: Adult; Aged; Aged, 80 and over; Anal Canal; Carbachol; Female; Humans; In Vitro Techniques; Male; Mi | 1993 |
In vitro response of the human anal canal longitudinal muscle layer to cholinergic and adrenergic stimulation: evidence of sphincter specialization.
Topics: Aged; Anal Canal; Carbachol; Dose-Response Relationship, Drug; Female; Humans; In Vitro Techniques; | 1993 |
Carbamylcholine-induced morphological changes and spatial dynamics of [Ca2+]c in Harderian glands of guinea pigs: calcium-dependent lipid secretion and contraction of myoepithelial cells.
Topics: Animals; Atropine; Calcium; Carbachol; Catecholamines; Cytosol; Guinea Pigs; Harderian Gland; Image | 1993 |
Relaxation by dexamethasone of isolated guinea-pig airways precontracted with endothelin-1.
Topics: Animals; Bronchi; Carbachol; Dexamethasone; Dose-Response Relationship, Drug; Endothelins; Guinea Pi | 1993 |
[Isolated smooth muscle cells of the human colon. Cytophysiological study].
Topics: Atropine; Carbachol; Colon; Colonic Neoplasms; Humans; Muscle Contraction; Muscle Relaxation; Muscle | 1993 |
Serotonin-induced muscle contraction in rat stomach fundus is mediated by a G alpha z-like guanine nucleotide binding protein.
Topics: Amino Acid Sequence; Animals; Carbachol; Gastric Mucosa; GTP-Binding Proteins; Guanine Nucleotides; | 1993 |
Micturition and premicturition contractions in unanesthetized rats with bladder outlet obstruction.
Topics: Adenosine Triphosphate; Animals; Atropine; Carbachol; Dose-Response Relationship, Drug; Female; Musc | 1994 |
Preservation of human small intestine: function of smooth muscle and nerve.
Topics: Adenosine; Allopurinol; Carbachol; Cold Temperature; Electric Stimulation; Glutathione; Humans; Ileu | 1993 |
Endothelin-1 and carbachol: differences in contractile effects and myosin phosphorylation in lamb tracheal smooth muscle.
Topics: Animals; Carbachol; Endothelins; In Vitro Techniques; Isometric Contraction; Muscle Contraction; Mus | 1993 |
Comparison of urinary bladder function in rats with hereditary diabetes insipidus, streptozotocin-induced diabetes mellitus, and nondiabetic osmotic diuresis.
Topics: Animals; Carbachol; Collagen; Diabetes Insipidus; Diabetes Mellitus, Experimental; Diuresis; Electri | 1994 |
X-ray diffraction study on mammalian visceral smooth muscles in resting and activated states.
Topics: Animals; Carbachol; Guinea Pigs; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Myosins; Phe | 1993 |
Effects of KC 399, a novel ATP-sensitive K+ channel opener, on electrical and mechanical responses in dog tracheal smooth muscle.
Topics: Adenosine Triphosphate; Animals; Benzopyrans; Carbachol; Cromakalim; Cyclic AMP; Cyclic GMP; Dogs; F | 1994 |
PPADS selectively antagonizes P2X-purinoceptor-mediated responses in the rabbit urinary bladder.
Topics: Adenosine Triphosphate; Animals; Carbachol; Dose-Response Relationship, Drug; In Vitro Techniques; M | 1993 |
Relevance of classification by size to topographical differences in bronchial smooth muscle response.
Topics: Animals; Animals, Newborn; Bronchi; Carbachol; Dogs; Electric Stimulation; Histamine; Histocytochemi | 1993 |
Effect of partial urethral obstruction on force development of the guinea pig bladder.
Topics: Animals; Carbachol; Disease Models, Animal; Electric Stimulation; Guinea Pigs; In Vitro Techniques; | 1993 |
Inhibitory effects of four inhaled anesthetics on canine tracheal smooth muscle contraction and intracellular Ca2+ concentration.
Topics: Anesthetics; Animals; Calcium; Carbachol; Dogs; Drug Interactions; Enflurane; Ethers; Halothane; Iso | 1993 |
Peripheral airway hyperresponsiveness in the choline-deficiently fed rat.
Topics: Acetylcholine; Acetylcholinesterase; Animals; Bronchial Hyperreactivity; Carbachol; Choline Deficien | 1993 |
Autoantibodies in HIV-infected patients that modulate the cholinergic activity of heart and gut tissue.
Topics: Animals; Atropine; Autoantibodies; Carbachol; Heart; HIV Infections; Humans; Immunoglobulins; In Vit | 1993 |
Novel regulation of muscarinic receptors and their coupling with G proteins in smooth muscle: transient resensitization during desensitizing process.
Topics: Animals; Carbachol; Cecum; Female; GTP-Binding Proteins; Guanine Nucleotides; Guanylyl Imidodiphosph | 1993 |
Pituitary adenylate cyclase-activating peptide is a potent modulator of human colonic motility.
Topics: 4-Aminopyridine; Apamin; Arginine; Carbachol; Colon, Sigmoid; Gastrointestinal Motility; Humans; In | 1993 |
Effect of in vitro exposure to acrolein on carbachol responses in rat trachealis muscle.
Topics: Acrolein; Animals; Arachidonic Acid; Carbachol; Dose-Response Relationship, Drug; In Vitro Technique | 1993 |
Changes in the contractile responses to carbachol and in the inhibitory effects of verapamil and nitrendipine on isolated smooth muscle preparations from rats subchronically exposed to Co2+ and Ni2+.
Topics: Animals; Carbachol; Cobalt; Ileum; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Ni | 1993 |
Organ culture with proinflammatory cytokines reproduces impairment of the beta-adrenoceptor-mediated relaxation in tracheas of a guinea pig antigen model.
Topics: Animals; Carbachol; Cytokines; Female; Guinea Pigs; Interleukin-1; Interleukin-2; Isoproterenol; Mus | 1993 |
Effects of terflavoxate on stimulated contractions of urinary bladder in vitro.
Topics: Animals; Calcium; Calcium Channel Blockers; Calcium Channels; Carbachol; Electric Stimulation; Flavo | 1993 |
Calcium mobilization by muscarinic cholinergic stimulation in bovine single airway smooth muscle.
Topics: Animals; Calcium; Calcium Channels; Carbachol; Cattle; Cell Survival; Diglycerides; Fura-2; Gallopam | 1993 |
Common phosphatidylinositol 4,5-bisphosphate pools are involved in carbachol and serotonin activation of tracheal smooth muscle.
Topics: Animals; Carbachol; Dogs; Drug Interactions; In Vitro Techniques; Muscle Contraction; Muscle, Smooth | 1993 |
Pharmacological profiles of muscarinic receptors in the longitudinal smooth muscle of guinea pig ileum.
Topics: Animals; Carbachol; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smoot | 1993 |
Direct inhibitory effect of neurotensin on isolated gastric smooth muscle cells of guinea pig via the cyclic GMP system.
Topics: Animals; Carbachol; Cells, Cultured; Cyclic GMP; Dideoxyadenosine; Guinea Pigs; In Vitro Techniques; | 1993 |
Increased cholinergic antagonism underlies impaired beta-adrenergic response in ovalbumin-sensitized guinea pigs.
Topics: Animals; Asthma; Carbachol; Dinoprostone; Female; Guinea Pigs; Histamine; Immunization; In Vitro Tec | 1993 |
SC-53606, a potent and selective antagonist of 5-hydroxytryptamine4 receptors in isolated rat esophageal tunica muscularis mucosae.
Topics: 4-Aminobenzoic Acid; Animals; Benzamides; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Hete | 1993 |
Effect of phospholipase C inhibitor U-73122 on antigen-induced airway smooth muscle contraction in guinea pigs.
Topics: Animals; Antigens; Carbachol; Cell Membrane Permeability; Dose-Response Relationship, Drug; Estrenes | 1993 |
Characterization of CCK receptors in a novel smooth muscle preparation from the guinea-pig stomach by use of the selective antagonists CI-988, L-365,260 and devazepide.
Topics: Animals; Benzodiazepinones; Carbachol; Cholecystokinin; Devazepide; Gastric Mucosa; Gastrins; Guinea | 1993 |
The influence of acute overdistension on rat bladder function and DNA synthesis.
Topics: Animals; Carbachol; DNA; Female; Muscle Contraction; Rats; Rats, Sprague-Dawley; Urinary Bladder; Ur | 1993 |
Maintenance of contractility in dissociated smooth muscle: low-density cultures in a defined medium.
Topics: Amnion; Animals; Buffers; Carbachol; Cell Division; Cells, Cultured; Culture Media; Cytological Tech | 1993 |
Tyrosine kinase inhibitors suppress agonist-induced contraction in smooth muscle.
Topics: Animals; Benzoquinones; Carbachol; Catechols; Dogs; Genistein; Guinea Pigs; In Vitro Techniques; Iso | 1993 |
Muscarinic M1 receptor agonist actions of muscarinic receptor agonists in rabbit vas deferens.
Topics: Animals; Atropine; Carbachol; Dose-Response Relationship, Drug; Hippocampus; Male; Muscarinic Antago | 1993 |
Role of Ca2+ entry in the modulation of airway tone by hypoxia.
Topics: Animals; Bronchi; Calcium; Carbachol; Carbon Dioxide; Dose-Response Relationship, Drug; Hypoxia; Ind | 1993 |
Signal transduction in smooth muscle cells from human airways.
Topics: Bronchi; Calcium; Carbachol; Cells, Cultured; Dinoprost; DNA; Histamine; Humans; Inositol Phosphates | 1993 |
Single-cell contraction assay for human ciliary muscle cells. Effect of carbachol.
Topics: Biological Assay; Carbachol; Cells, Cultured; Ciliary Body; Humans; Muscle Contraction; Muscles; Pil | 1993 |
Subtype of muscarinic receptors mediating relaxation and contraction in the rat iris dilator smooth muscle.
Topics: Alkaloids; Animals; Atropine; Carbachol; Furans; In Vitro Techniques; Iris; Male; Muscle Contraction | 1993 |
Effect of testosterone on the response of young rat vas deferens to norepinephrine.
Topics: Animals; Barium; Barium Compounds; Carbachol; Chlorides; Cocaine; Estradiol; In Vitro Techniques; Ma | 1993 |
Synthesis and antimuscarinic activity of some 1-cycloalkyl-1-hydroxy-1-phenyl-3-(4-substituted piperazinyl)-2-propanones and related compounds.
Topics: Animals; Carbachol; Electric Stimulation; Guinea Pigs; Male; Molecular Conformation; Molecular Struc | 1993 |
Secretin receptors mediating rat forestomach relaxation.
Topics: Animals; Autoradiography; Binding, Competitive; Carbachol; Gastric Mucosa; In Vitro Techniques; Iodi | 1993 |
Altered small intestinal smooth muscle function in Crohn's disease.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Carbachol; Crohn Disease; Dose-Response Relationship, Dr | 1993 |
[Pharmacologic characterization of formoterol in comparison with isoprenaline, fenoterol and salbutamol in tracheal muscle strips and lung membranes of the guinea pig].
Topics: Airway Resistance; Albuterol; Animals; Carbachol; Culture Techniques; Dose-Response Relationship, Dr | 1993 |
Heterogeneous contractile responses of single smooth muscle cells from guinea pig ileum.
Topics: Animals; Carbachol; Cells, Cultured; Dose-Response Relationship, Drug; Guinea Pigs; Ileum; Muscle Co | 1993 |
Airway smooth muscle shortening in excised canine lung lobes.
Topics: Airway Resistance; Animals; Carbachol; Dogs; In Vitro Techniques; Lung; Lung Compliance; Muscle Cont | 1993 |
Dual action of ranitidine at cholinergic sites in the rat isolated anococcygeus muscle.
Topics: Acetylcholine; Animals; Carbachol; Cholinergic Fibers; Dose-Response Relationship, Drug; Drug Intera | 1993 |
Are m-cholinoceptors of guinea pig gallbladder smooth muscle of m4 subtype?
Topics: Animals; Carbachol; Cholinergic Antagonists; Female; Gallbladder; Guinea Pigs; Male; Muscle Contract | 1993 |
Endothelin subtypes: effect on isolated rhesus monkey ciliary muscle.
Topics: Animals; Atropine; Carbachol; Ciliary Body; Endothelins; In Vitro Techniques; Macaca mulatta; Muscle | 1995 |
Regional variations in the neural control of the female pig urethra.
Topics: Acetylcholinesterase; Animals; Carbachol; Female; Immunohistochemistry; Muscle Contraction; Muscle, | 1995 |
Site of action of galanin in the cholinergic transmission of guinea pig small intestine.
Topics: Acetylcholine; Animals; Carbachol; Electric Stimulation; Female; Galanin; gamma-Aminobutyric Acid; G | 1995 |
Induction of human airway hyperresponsiveness by tumour necrosis factor-alpha.
Topics: Acetylcholine; Aged; Allergens; Bronchi; Bronchial Hyperreactivity; Carbachol; Electric Stimulation; | 1995 |
LFA-1, and not Mac-1, is crucial for the development of hyperreactivity in a murine model of nonallergic asthma.
Topics: Animals; Antibodies, Monoclonal; Asthma; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Ca | 1996 |
Effects of IZP-94005 (contignasterol) on antigen-induced bronchial responsiveness in ovalbumin-sensitized guinea-pigs.
Topics: Administration, Inhalation; Airway Resistance; Analysis of Variance; Animals; Anti-Asthmatic Agents; | 1995 |
Characterization of muscarinic receptors mediating contractions of circular and longitudinal muscle of human isolated colon.
Topics: Alkaloids; Atropine; Carbachol; Carcinoma; Colon; Colonic Neoplasms; Dose-Response Relationship, Dru | 1995 |
Inhibitory action of PPADS on relaxant responses to adenine nucleotides or electrical field stimulation in guinea-pig taenia coli and rat duodenum.
Topics: Adenosine; Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Carbachol; Colon; Dose-Respon | 1995 |
Characterization of the functional muscarinic receptors in the rat urinary bladder.
Topics: Animals; Carbachol; Dioxolanes; Electric Stimulation; In Vitro Techniques; Male; Muscarinic Agonists | 1995 |
In vivo and in vitro effects of muscarinic receptor antagonists on contractions and release of [3H]acetylcholine in the rabbit urinary bladder.
Topics: Acetylcholine; Animals; Carbachol; Diamines; Female; Gallamine Triethiodide; Muscarinic Antagonists; | 1995 |
Mechanisms involved in electrically-induced responses of rat seminal vesicles.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Atropine; Carbachol; Clonidine; El | 1995 |
Further evidence that tachykinin-induced contraction of human isolated bronchus is mediated only by NK2-receptors.
Topics: Aged; Bronchi; Carbachol; Female; Glycopeptides; Humans; Male; Middle Aged; Muscle Contraction; Neur | 1995 |
Smooth muscle contractility after intestinal resection.
Topics: Adaptation, Physiological; Animals; Carbachol; Dogs; In Vitro Techniques; Jejunum; Muscle Contractio | 1996 |
Cocaine: mechanism of inhibition of a muscle acetylcholine receptor studied by a laser-pulse photolysis technique.
Topics: Animals; Carbachol; Cell Line; Cholinergic Antagonists; Cocaine; Ion Channel Gating; Ion Channels; K | 1995 |
Neomycin selectively inhibits 5-hydroxytryptamine-induced contraction in the guinea pig trachea.
Topics: Animals; Anti-Bacterial Agents; Calcium; Calcium Channels; Calcium Channels, L-Type; Carbachol; Guin | 1996 |
Impaired intracellular signal transduction in gastric smooth muscle of diabetic BB/W rats.
Topics: Acetylcholine; Animals; Calcium; Carbachol; Cell Membrane; Cells, Cultured; Cytosol; Diabetes Mellit | 1996 |
Nitric oxide-sensitive and -insensitive contractions of the isolated rabbit iris sphincter muscle.
Topics: Animals; Arginine; Benzoates; Carbachol; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Inhibi | 1996 |
A nitric oxide-sensitive electrode: requirement of lower oxygen concentration for detecting nitric oxide from the tissue.
Topics: Animals; Aorta, Thoracic; Arginine; Carbachol; Electrodes; Guinea Pigs; Male; Muscle Contraction; Mu | 1996 |
The effects of endothelin-1 on isolated bovine ciliary muscles.
Topics: Animals; Carbachol; Cattle; Ciliary Body; Dose-Response Relationship, Drug; Endothelins; Miotics; Mu | 1995 |
Positive inotropic effects of the calcium sensitizer CGP 48506 in failing human myocardium.
Topics: 1-Methyl-3-isobutylxanthine; Azocines; Calcium; Carbachol; Cardiotonic Agents; Dose-Response Relatio | 1996 |
Influence of strip size and location on contractile responses of rat urinary bladder body strips.
Topics: Adenosine Triphosphate; Animals; Atropine; Bethanechol Compounds; Carbachol; Male; Muscarinic Agonis | 1995 |
Dantrolene blocks the tonic contractions to carbachol and histamine with smaller effects on the phasic due to release of intracellular Ca2+ in ileal longitudinal muscle.
Topics: Animals; Calcium; Carbachol; Dantrolene; Guinea Pigs; Histamine Antagonists; Ileum; Male; Muscle Con | 1995 |
Gallbladder motility in vitro in men with gallstones following Billroth II gastric resection.
Topics: Aged; Aged, 80 and over; Carbachol; Cholecystectomy; Cholelithiasis; Duodenal Ulcer; Gallbladder; Hu | 1996 |
In vitro contractility of stimulated and non-stimulated human gallbladder muscle.
Topics: Carbachol; Electric Stimulation; Gallbladder; Humans; In Vitro Techniques; Muscle Contraction; Muscl | 1996 |
[The reactivity of canine colonic and ileal smooth muscle to carbachol (Jestryl)].
Topics: Animals; Carbachol; Cholinergic Agents; Colon; Dogs; Dose-Response Relationship, Drug; Ileum; In Vit | 1994 |
Selective enhancement by an adenosine A1 receptor agonist of agents inducing contraction of the rat vas deferens.
Topics: Adenosine; Adenosine Triphosphate; Adrenergic alpha-Antagonists; Animals; Bradykinin; Carbachol; Dos | 1996 |
Presence of functional type B natriuretic peptide receptor in human ocular cells.
Topics: 1-Methyl-3-isobutylxanthine; Atrial Natriuretic Factor; Calcium; Carbachol; Cell Line, Transformed; | 1996 |
Mechanisms of the suppression of the bladder activity by flavoxate.
Topics: Animals; Atropine; Calcium; Carbachol; Cats; Electric Stimulation; Female; Flavoxate; Injections, In | 1996 |
Direct inhibitory effect of thyrotropin-releasing hormone on isolated cecal circular smooth muscle cells of guinea pig.
Topics: Aminoquinolines; Animals; Arginine; Carbachol; Cecum; Cell Size; Cyclic AMP; Cyclic GMP; Enzyme Inhi | 1996 |
Inhibition of bronchospasm and ozone-induced airway hyperresponsiveness in the guinea-pig by CDP840, a novel phosphodiesterase type 4 inhibitor.
Topics: Analysis of Variance; Animals; Benzamides; Bronchial Hyperreactivity; Bronchoconstriction; Carbachol | 1996 |
Sensitivity differences to 5-HT and carbachol in subsections of the isolated rat stomach fundus strip: an improved preparation.
Topics: Animals; Carbachol; Dose-Response Relationship, Drug; Female; Gastric Fundus; Gastric Mucosa; Male; | 1996 |
Droperidol inhibits tracheal contraction induced by serotonin, histamine or carbachol in guinea pigs.
Topics: Anesthetics, Intravenous; Animals; Carbachol; Droperidol; Female; Guinea Pigs; Histamine; In Vitro T | 1996 |
ATP and beta,gamma-methylene ATP produce relaxation of guinea-pig isolated trachealis muscle via actions at P1 purinoceptors.
Topics: Adenosine Triphosphate; Animals; Carbachol; Female; Guinea Pigs; In Vitro Techniques; Indomethacin; | 1996 |
Specific cyclic nucleotide phosphodiesterase inhibitors differently modulate contractile kinetics in airway smooth muscle.
Topics: Animals; Carbachol; Cattle; Cyclic AMP; Cyclic GMP; Cytosol; Dogs; Guinea Pigs; Isoenzymes; Kinetics | 1995 |
Major difference between rat and guinea-pig ureter in the ability of agonists and caffeine to release Ca2+ and influence force.
Topics: Animals; Caffeine; Calcium; Carbachol; Guinea Pigs; Male; Membrane Potentials; Muscle Contraction; M | 1995 |
A morphometric and functional study of the toxicity of atmospheric ammonia in the extrathoracic airways in pigs.
Topics: Adrenergic beta-Agonists; Air Pollutants; Ammonia; Animals; Carbachol; Cell Nucleus; Dose-Response R | 1996 |
beta-Adrenoceptor agonists-induced desensitization in rat trachea.
Topics: Adrenergic beta-Agonists; Albuterol; Animals; Carbachol; Dinoprostone; In Vitro Techniques; Isoprote | 1995 |
Effect of prostaglandins on cultured porcine iris sphincter muscle cells.
Topics: Animals; Carbachol; Cells, Cultured; Cyclic AMP; Dinoprost; Dinoprostone; Iris; Muscarinic Agonists; | 1996 |
Pharmacological characteristics of BDTI, a new isoquinoline-derived beta 2-adrenoceptor agonist, in canine trachea and rat heart.
Topics: Adrenergic beta-2 Receptor Agonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Albutero | 1996 |
Hypoxic constrictor response in the isolated pulmonary artery from chronically hypoxic rats.
Topics: Animals; Body Weight; Carbachol; Endothelium, Vascular; Enzyme Inhibitors; Hypoxia; Male; Muscle Con | 1996 |
Carbachol but not acetylcholine inhibits contraction by the protein kinase C-dependent and -independent pathways in the smooth muscle of guinea pig taenia caeci.
Topics: Acetylcholine; Animals; Carbachol; Cecum; Cholinergic Agents; Dose-Response Relationship, Drug; Guin | 1996 |
Effects of external K+ on depletion-induced Ca2+ entry in rat ileal smooth muscle.
Topics: Animals; Calcium; Calcium-Transporting ATPases; Carbachol; Dose-Response Relationship, Drug; Enzyme | 1996 |
Involvement of protein kinase C in muscarinic agonist-induced contractions of guinea pig ileal longitudinal muscle.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Calcium; Carbachol; Diglycerides; Guinea Pig | 1996 |
Role of Rho proteins in carbachol-induced contractions in intact and permeabilized guinea-pig intestinal smooth muscle.
Topics: Adenosine Diphosphate Ribose; Animals; Bacterial Proteins; Bacterial Toxins; Calcium; Carbachol; Cho | 1996 |
Endogenous nitric oxide contributes to strain-related differences in airway responsiveness in rats.
Topics: Animals; Bronchial Hyperreactivity; Carbachol; Cyclic AMP; Cyclic GMP; Enzyme Inhibitors; Epithelium | 1996 |
Pharmacological activation changes stiffness of cultured human airway smooth muscle cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Acetylcholine; Actins; Bradykinin; Bronchodilator Agents; Bu | 1996 |
Caffeine- and carbachol-induced Cl- and cation currents in single opossum esophageal circular muscle cells.
Topics: Animals; Caffeine; Calcium; Carbachol; Cations; Cell Membrane; Chlorides; Esophagus; In Vitro Techni | 1996 |
Involvement of G alpha q/11 in the contractile signal transduction pathway of muscarinic M3 receptors in caecal smooth muscle.
Topics: Animals; Antibodies; Carbachol; Cecum; Enzyme Activation; GTP-Binding Proteins; Male; Muscarinic Ago | 1996 |
Effect of treatment with calcium antagonists in vitro and in vivo on the contractile response of isolated rat and human detrusor muscle.
Topics: Animals; Calcium Channel Blockers; Carbachol; Electric Stimulation; Female; Humans; In Vitro Techniq | 1996 |
The role of nitric oxide in ethanol-induced gastrointestinal dysfunction.
Topics: Animals; Carbachol; Cats; Esophagogastric Junction; Esophagus; Ethanol; Male; Muscle Contraction; Mu | 1996 |
Relaxant responses by optical isomers of ephedrine and methylephedrine in guinea pig tracheal smooth muscle.
Topics: Animals; Butoxamine; Carbachol; Ephedrine; Guinea Pigs; Histamine; In Vitro Techniques; Male; Muscle | 1996 |
Physiological effects of a novel bioactive agent.
Topics: Animals; Carbachol; Electric Stimulation; Heterocyclic Compounds; In Vitro Techniques; Male; Muscle | 1996 |
Evidence for the presence of regional differences in the subtype specificity of muscarinic receptors in rabbit lower urinary tract.
Topics: Animals; Atropine; Carbachol; Diamines; Female; Muscarinic Antagonists; Muscle Contraction; Muscle, | 1997 |
The effects of gamma-radiation on intestinal motor activity and faecal pellet expulsion in the guinea pig.
Topics: Animals; Carbachol; Defecation; Dimethylphenylpiperazinium Iodide; Dose-Response Relationship, Drug; | 1996 |
Steric aspects of formoterol and terbutaline: is there an adverse effect of the distomer on airway smooth muscle function?
Topics: Adrenergic beta-Agonists; Animals; Bronchi; Bronchial Hyperreactivity; Carbachol; Choline; Electric | 1996 |
Canine bronchial sustained contraction in Ca2+-free medium: role of intracellular Ca2+.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1996 |
Histamine-induced contraction of human isolated bronchus is enhanced by endogenous prostaglandin F2 alpha and activation of TP receptors.
Topics: Bridged Bicyclo Compounds, Heterocyclic; Bronchi; Carbachol; Cholinergic Agonists; Dinoprost; Fatty | 1997 |
Effect of transmural pressure on preloads and collapse of immature bronchi.
Topics: Aging; Animals; Animals, Newborn; Biomechanical Phenomena; Bronchi; Bronchoscopy; Carbachol; Complia | 1997 |
Activation of non-selective cation conductance by carbachol in freshly isolated bovine ciliary muscle cells.
Topics: Animals; Calcium; Carbachol; Cations; Cattle; Ciliary Body; Electrophysiology; In Vitro Techniques; | 1997 |
Apamin blocks the direct relaxant effect of melatonin on rat ileal smooth muscle.
Topics: 4-Aminopyridine; Adrenergic alpha-Antagonists; Animals; Apamin; Calcium; Calcium Channel Blockers; C | 1997 |
Comparison of oxybutynin and its active metabolite, N-desethyl-oxybutynin, in the human detrusor and parotid gland.
Topics: Adult; Aged; Atropine; Carbachol; Humans; In Vitro Techniques; Mandelic Acids; Middle Aged; Muscarin | 1997 |
Ketamine relaxes airway smooth muscle contracted by endothelin.
Topics: Anesthetics, Dissociative; Animals; Calcium; Calcium Channels; Carbachol; Egtazic Acid; Endothelin-1 | 1997 |
Glucocorticoid modulation of muscarinic and beta-adrenergic receptors in guinea pig lung.
Topics: Analysis of Variance; Animals; Carbachol; Drug Evaluation, Preclinical; Glucocorticoids; Guinea Pigs | 1997 |
Functional and molecular evidence for beta 1-, beta 2- and beta 3- adrenoceptors in human colon.
Topics: Adrenergic beta-Agonists; Carbachol; Colon; Humans; In Vitro Techniques; Isoproterenol; Muscle Contr | 1997 |
Effects of protein tyrosine kinase inhibitors on contractility of isolated bronchioles of the rat.
Topics: Acetylcholine; Animals; Bronchi; Caffeic Acids; Carbachol; Cinnamates; Enzyme Inhibitors; Epidermal | 1997 |
Antagonist inhibition curves and the measurement of dissociation constants.
Topics: Animals; Binding, Competitive; Carbachol; Dose-Response Relationship, Drug; Guinea Pigs; Ileum; In V | 1997 |
Activation of M2 muscarinic receptors in guinea-pig ileum opens cationic channels modulated by M3 muscarinic receptors.
Topics: Animals; Carbachol; Guinea Pigs; Ileum; In Vitro Techniques; Ion Channels; Muscarinic Antagonists; M | 1997 |
Dual roles of phorbol 12, 13-dibutyrate in the regulation of guinea-pig gastric contraction.
Topics: Animals; Calcium; Carbachol; Guinea Pigs; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; P | 1997 |
Post-synaptic 5-HT4 receptor modulation of tachykinergic excitation of rat oesophageal tunica muscularis mucosae.
Topics: 5-Methoxytryptamine; Animals; Carbachol; Esophagus; In Vitro Techniques; Male; Muscle Contraction; M | 1997 |
Localization of leukaemia inhibitory factor to airway epithelium and its amplification of contractile responses to tachykinins.
Topics: Animals; Capsaicin; Carbachol; Epithelium; Female; Growth Inhibitors; Guinea Pigs; Humans; Immunohis | 1997 |
Effects of intravenous anesthetics on the contraction and response of rat trachea to phosphatidylinositol.
Topics: Analysis of Variance; Anesthetics, Intravenous; Animals; Carbachol; Fentanyl; Ketamine; Male; Midazo | 1997 |
The effect of anoxia and glucose-free solutions on the contractile response of guinea-pig detrusor strips to intrinsic nerve stimulation and the application of excitatory agonists.
Topics: Adenosine Triphosphate; Animals; Carbachol; Dose-Response Relationship, Drug; Electric Stimulation; | 1997 |
Calcium independent contraction of bladder smooth muscle.
Topics: Aged; Animals; Caffeine; Calcium; Calmodulin; Carbachol; Culture Media; Enzyme Inhibitors; Humans; I | 1997 |
The effect of ovariectomy on the contractile response of the rat isolated detrusor muscle and urethra.
Topics: Animals; Carbachol; Dose-Response Relationship, Drug; Female; Muscle Contraction; Norepinephrine; Ov | 1997 |
Effects of castration on adrenergic, cholinergic and nonadrenergic, noncholinergic responses of isolated corpus cavernosum from rabbit.
Topics: Adenosine; Adrenergic alpha-Agonists; Animals; Carbachol; Electric Stimulation; Male; Muscle Contrac | 1997 |
Hydrogen peroxide induced responses of cat tracheal smooth muscle cells.
Topics: Animals; Calcium; Carbachol; Cats; Cells, Cultured; Electric Stimulation; Female; Hydrogen Peroxide; | 1997 |
Cholinesterase activity in human pulmonary arteries and veins.
Topics: Acetylcholine; Adrenergic alpha-Agonists; Carbachol; Cholinesterase Inhibitors; Cholinesterases; Fem | 1997 |
F-actin disruption attenuates agonist-induced [Ca2+], myosin phosphorylation, and force in smooth muscle.
Topics: Actins; Animals; Calcium; Carbachol; Cattle; Cytochalasin B; Cytochalasin D; In Vitro Techniques; Ki | 1997 |
The inhibitory effect of fluoride on carbachol-induced bovine bronchial contraction.
Topics: Animals; Bronchi; Carbachol; Cattle; Dose-Response Relationship, Drug; Muscle Contraction; Muscle, S | 1997 |
Effects of phorbol ester on carbachol-induced contraction in bovine ciliary muscle: possible involvement of protein kinase C.
Topics: Animals; Carbachol; Cattle; Ciliary Body; Drug Interactions; Histones; In Vitro Techniques; Muscarin | 1997 |
Calcium release from intracellular stores and excitation-contraction coupling in intestinal smooth muscle.
Topics: Animals; Caffeine; Calcium; Calcium Channel Blockers; Carbachol; Cell Compartmentation; Cells, Cultu | 1997 |
The role of cyclic nucleotides in guinea-pig bladder contractility.
Topics: Animals; Carbachol; Colforsin; Cyclic AMP; Electric Stimulation; Female; Guinea Pigs; In Vitro Techn | 1997 |
Different responsiveness to nitric oxide-cyclic guanosine monophosphate pathway in cholinergic and tachykinergic contractions of the rabbit iris sphincter muscle.
Topics: Animals; Carbachol; Cyclic GMP; Cyclic N-Oxides; Female; Free Radical Scavengers; Imidazoles; Iris; | 1997 |
ARF-independent inhibition of the carbachol-induced contractions by brefeldin A in intestinal smooth muscle.
Topics: ADP-Ribosylation Factor 1; ADP-Ribosylation Factors; Animals; Brefeldin A; Calcium Channel Blockers; | 1997 |
Persistent intestinal neuromuscular dysfunction after acute nematode infection in mice.
Topics: Animals; Biomarkers; Carbachol; Electric Stimulation; In Vitro Techniques; Inflammation; Intestinal | 1997 |
Effects of various selective phosphodiesterase inhibitors on muscle contractility in guinea pig ileal longitudinal smooth muscle.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Calcium; Carbachol; Cell Membrane Permeability; Cyclic AMP; Cy | 1997 |
Inhibition of antigen-induced muscle contractions by inhibitors of thromboxane pathway in rat small intestine.
Topics: Animals; Antigens; Atropine; Benzimidazoles; Benzoxepins; Carbachol; Cyclooxygenase Inhibitors; Dose | 1997 |
Contractile effects of porcine galanin(1-29)-NH2 on the rat isolated gastric fundus: mediation by potassium ions.
Topics: Animals; Buffers; Carbachol; Female; Galanin; Gastric Fundus; In Vitro Techniques; Male; Muscle Cont | 1997 |
Anticholinergic and calcium antagonistic activities of NS-21 contribute to the inhibition of rat urinary bladder contractions.
Topics: Animals; Calcium Channel Blockers; Calcium Chloride; Calcium Radioisotopes; Carbachol; Cholinergic A | 1997 |
Beneficial effects of Tadenan therapy after two weeks of partial obstruction in the rabbit.
Topics: Animals; Carbachol; Compliance; Fatty Alcohols; Male; Muscle Contraction; Organ Size; Peanut Oil; Pl | 1997 |
Antimuscarinic potency and bladder selectivity of PNU-200577, a major metabolite of tolterodine.
Topics: Acetylcholine; Animals; Benzhydryl Compounds; Carbachol; Cats; CHO Cells; Cresols; Cricetinae; Dose- | 1997 |
Pinaverium acts as L-type calcium channel blocker on smooth muscle of colon.
Topics: Animals; Calcium Channel Blockers; Carbachol; Colon; Colonic Diseases, Functional; Dogs; Dose-Respon | 1997 |
The adrenal medulla as a wet sponge: a role for the intramedullary venous vasculature?
Topics: Adrenal Medulla; Animals; Carbachol; Cattle; Cholinergic Agonists; Electric Stimulation; Endothelins | 1997 |
DMPP causes relaxation of rat distal colon by a purinergic and a nitrergic mechanism.
Topics: Adenosine Triphosphate; Anesthetics, Local; Animals; Carbachol; Colon; Dimethylphenylpiperazinium Io | 1997 |
Regulation of intracellular calcium in human esophageal smooth muscles.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1997 |
Actions of C-type natriuretic peptide and sodium nitroprusside on carbachol-stimulated inositol phosphate formation and contraction in ciliary and iris sphincter smooth muscles.
Topics: Aminoquinolines; Animals; Atrial Natriuretic Factor; Carbachol; Cats; Cattle; Ciliary Body; Cyclic A | 1997 |
Depletion of either ryanodine- or IP3-sensitive calcium stores activates capacitative calcium entry in mouse anococcygeus smooth muscle cells.
Topics: Animals; Caffeine; Calcium; Calcium-Transporting ATPases; Carbachol; Central Nervous System Stimulan | 1998 |
Effect of Ca2+-channel blockers on isoprenaline-induced desensitization in rat trachea.
Topics: Animals; Calcium Channel Blockers; Carbachol; In Vitro Techniques; Isoproterenol; Male; Muscle Contr | 1997 |
Differential responsiveness to contractile agents of isolated smooth muscle cells from human colons as a function of age and inflammation.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Carbachol; Colitis; Colon; Female; Humans; Male; Middle | 1997 |
Comparison of effect of mosapride citrate and existing 5-HT4 receptor agonists on gastrointestinal motility in vivo and in vitro.
Topics: Animals; Benzamides; Carbachol; Dogs; Female; Gastrointestinal Motility; Guinea Pigs; In Vitro Techn | 1997 |
Stereoselectivity of butylidenephthalide on voltage-dependent calcium channels in guinea-pig isolated ileum.
Topics: Animals; Calcium Channels; Carbachol; Guinea Pigs; Ileum; Male; Muscle Contraction; Parasympatholyti | 1997 |
Concentration-dependent stimulation of cholinergic motor nerves or smooth muscle by [Nle13]motilin in the isolated rabbit gastric antrum.
Topics: Animals; Carbachol; Dose-Response Relationship, Drug; Electric Stimulation; Enteric Nervous System; | 1997 |
Difference in the endothelium mediated effects of A23187 on thoracic aorta between neonatal and adult guinea pigs.
Topics: Animals; Animals, Newborn; Aorta, Thoracic; Calcimycin; Carbachol; Dose-Response Relationship, Drug; | 1997 |
Myogenic and neurogenic mechanisms and arachidonate metabolites in bronchial muscle response to allergen.
Topics: Allergens; Animals; Arachidonic Acids; Ascaris suum; Bronchi; Bronchial Hyperreactivity; Carbachol; | 1997 |
Effect of different ozone concentrations on the neurogenic contraction and relaxation of guinea pig airways.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Adrenergic Fibers; Animals; Atropine; Bronchi | 1997 |
Smooth muscle electromyography of the urinary bladder.
Topics: Animals; Carbachol; Electromyography; Electronic Data Processing; Female; Fourier Analysis; Microele | 1998 |
Protein kinase C mediates increase of Ca2+ sensitivity for contraction by cholinoceptor partial agonist in ileal longitudinal muscle of guinea pig.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Calcium; Carbachol; Carbazoles; Cholinergic | 1998 |
Release of epithelium-derived PGE2 from canine trachea after antigen inhalation.
Topics: Administration, Inhalation; Allergens; Animals; Antigens, Helminth; Ascaris suum; Asthma; Bronchial | 1998 |
Nitrergic and cholinergic innervation of the rat lower urinary tract after pelvic ganglionectomy.
Topics: Acetylcholine; Animals; Carbachol; Cyclic GMP; Electric Stimulation; Female; Ganglia; Ganglionectomy | 1998 |
Prejunctional M1 facilitory and M2 inhibitory muscarinic receptors mediate rat bladder contractility.
Topics: Animals; Blotting, Northern; Carbachol; Electric Stimulation; Male; Muscarinic Agonists; Muscarinic | 1998 |
Effect of ischemia-reperfusion on contractile function of rat urinary bladder: possible role of nitric oxide.
Topics: Animals; Carbachol; Male; Muscle Contraction; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rep | 1998 |
Characterization of muscarinic receptors mediating the contraction of the urinary detrusor muscle in cynomolgus monkeys and guinea pigs.
Topics: Animals; Carbachol; Diamines; Female; Guinea Pigs; Macaca fascicularis; Male; Muscarinic Agonists; M | 1998 |
Physiological effects of macrocycle 1 on the rabbit corpus cavernosum.
Topics: Adenosine Triphosphate; Animals; Carbachol; Dose-Response Relationship, Drug; Electric Stimulation; | 1998 |
Nitric oxide relaxes bovine ciliary muscle contracted by carbachol through elevation of cyclic GMP.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Carbachol; Cattle; Cil | 1998 |
The mechanism of Ca2+ release from the SR of permeabilised guinea-pig and rat ureteric smooth muscle.
Topics: Animals; Caffeine; Calcium-Transporting ATPases; Carbachol; Cell Membrane Permeability; Enzyme Inhib | 1998 |
The effects of excretions/secretions of Ostertagia circumcincta on ovine abomasal tissues in vitro.
Topics: Abomasum; Animals; Carbachol; Dose-Response Relationship, Drug; Female; Gastric Mucosa; In Vitro Tec | 1998 |
Impaired contraction and relaxation in the aorta of streptozotocin-diabetic rats.
Topics: Adenosine; Adenosine Triphosphate; Animals; Aorta, Thoracic; Carbachol; Diabetes Mellitus, Experimen | 1998 |
Digital analysis of the pharmacological effects of in vitro ischemia on rabbit corpus cavernosum.
Topics: Animals; Carbachol; Computer Simulation; Ischemia; Male; Muscarinic Agonists; Muscle Contraction; Mu | 1998 |
Pharmacological and molecular characterization of muscarinic receptors in cat esophageal smooth muscle.
Topics: Amino Acid Sequence; Animals; Base Sequence; Carbachol; Cats; Dioxoles; Electric Stimulation; Esopha | 1998 |
Use of abdominal fascia to create partial outlet obstruction in rabbits.
Topics: Adenosine Triphosphate; Animals; Carbachol; Disease Models, Animal; Electric Stimulation; Male; Musc | 1998 |
Effects of corticosteroids on epithelial structure and smooth muscle function of rat trachea.
Topics: Animals; Atrophy; Carbachol; Epithelium; Glucocorticoids; Male; Muscle Contraction; Muscle, Smooth; | 1998 |
Long- and short-acting beta2 adrenoceptor agonists: interactions in human contracted bronchi.
Topics: Adrenergic beta-Agonists; Albuterol; Bronchi; Carbachol; Dose-Response Relationship, Drug; Drug Inte | 1998 |
Length-dependent modulation of smooth muscle activation: effects of agonist, cytochalasin, and temperature.
Topics: Animals; Carbachol; Cattle; Cytochalasin D; Muscarinic Agonists; Muscle Contraction; Muscle, Smooth; | 1998 |
Differential effects of progesterone and its analogues on the contractility of the murine jejunum in vitro.
Topics: 20-alpha-Dihydroprogesterone; Animals; Carbachol; Female; Gastrointestinal Motility; Gonanes; Hormon | 1998 |
Effects of chylomicrons and chylomicron remnants on endothelium-dependent relaxation of rat aorta.
Topics: Adenosine Triphosphate; Animals; Aorta; Calcimycin; Carbachol; Chylomicrons; Dose-Response Relations | 1998 |
Involvement of intracellular Ca2+ stores in inhibitory effects of NO donor SIN-1 and cGMP.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1998 |
Effect of cAMP- and cGMP-related drugs on porcine cultured ciliary muscle.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Antihypertensive Agents; Bucladesine; Carbachol; Cells, Cultur | 1998 |
Differential regulation of beta3-adrenoceptors in gut and adipose tissue of genetically obese (ob/ob) C57BL/6J-mice.
Topics: Adipose Tissue; Adipose Tissue, Brown; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animal | 1998 |
Effects of diabetes mellitus on the contractile activity of carbachol and galanin in isolated gastric fundus strips of rats.
Topics: Animals; Carbachol; Diabetes Mellitus, Experimental; Enzyme Inhibitors; Galanin; Gastric Fundus; Hyp | 1998 |
Effect of repetitive stimulation on the contractile response of rabbit urinary bladder subjected to in vitro hypoxia or in vitro ischemia followed by reoxygenation.
Topics: Animals; Carbachol; Cell Hypoxia; Disease Models, Animal; Electric Stimulation; Glucose; In Vitro Te | 1998 |
Selective potentiation by ouabain of naloxone-induced withdrawal contractions of isolated guinea-pig ileum following acute exposure to morphine.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Carbachol; Clonidine; Drug Synergi | 1998 |
Ketamine inhibits the tonic response to carbachol and histamine in the guinea pig trachea.
Topics: Anesthetics, Dissociative; Animals; Bronchoconstrictor Agents; Buffers; Calcium; Carbachol; Chelatin | 1998 |
InsP3, but not novel Ca2+ releasers, contributes to agonist-initiated contraction in rabbit airway smooth muscle.
Topics: Adenosine Diphosphate Ribose; Administration, Topical; Anesthetics, Local; Animals; Anti-Inflammator | 1998 |
Regionally different influence of contractile agonists on isolated rat airway segments.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Bradykinin; Bronchi; Ca | 1998 |
Nitric oxide-mediated relaxation induced by bradykinin in the isolated mouse trachea.
Topics: Animals; Aspirin; Bradykinin; Carbachol; Female; Glycine; In Vitro Techniques; Male; Mice; Muscle Co | 1998 |
Comparison of contractions produced by carbachol, thapsigargin and cyclopiazonic acid in the guinea-pig tracheal muscle.
Topics: Animals; Cadmium; Calcium Channel Blockers; Carbachol; Female; Guinea Pigs; Imidazoles; In Vitro Tec | 1998 |
Motor responsiveness of proximal and distal human colonic muscle layers to carbachol and neurotensin.
Topics: Adult; Aged; Aged, 80 and over; Carbachol; Colon; Dose-Response Relationship, Drug; Female; Humans; | 1998 |
Effects of LTD4 on human airway smooth muscle cell proliferation, matrix expression, and contraction In vitro: differential sensitivity to cysteinyl leukotriene receptor antagonists.
Topics: Asthma; Carbachol; Cells, Cultured; Chromones; Dicarboxylic Acids; DNA Replication; Epidermal Growth | 1998 |
Inhibitory effects of isradipine on spontaneous and oxytocin- and carbachol-stimulated contractions of rat myometrium.
Topics: Animals; Calcium Channel Blockers; Carbachol; Dose-Response Relationship, Drug; Drug Interactions; F | 1998 |
Calcium source diversity in canine lower esophageal sphincter muscle.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1998 |
Evidence for the presence of muscarinic M2 and M4 receptors in guinea-pig gallbladder smooth muscle.
Topics: Adenylyl Cyclases; Animals; Binding, Competitive; Blotting, Western; Carbachol; Female; Gallbladder; | 1998 |
Characterization of the muscarinic receptor mediating contraction of the dog prostate.
Topics: Acetylcholine; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Carbachol; Cholin | 1998 |
Pharmacological characteristics of MJ-451, a new benzopyran- derived ATP-sensitive potassium channel opener, in guinea pig isolated trachea.
Topics: Animals; Benzopyrans; Carbachol; Cromakalim; Drug Interactions; Female; Guinea Pigs; Histamine; Male | 1998 |
Characterization of neural control and contractile function in airway smooth muscle of the ferret.
Topics: Acetylcholine; Adrenergic Agonists; Animals; Bronchoconstriction; Bronchoconstrictor Agents; Carbach | 1998 |
In vitro pharmacologic profile of YM158, a new dual antagonist for LTD4 and TXA2 receptors.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Carbachol; Dinoprost; G | 1998 |
Effect of estradiol on rat ileum.
Topics: Animals; Carbachol; Cholinergic Agonists; Estradiol; Ileum; In Vitro Techniques; Male; Muscle Contra | 1998 |
Biphasic relaxant response of ovine trachealis muscle to electrical field stimulation: influence of cooling.
Topics: Analysis of Variance; Animals; Atropine; Capsaicin; Carbachol; Cold Temperature; Electric Stimulatio | 1999 |
Inhibitors of spasmogen-induced Ca2+ channel suppression in smooth muscle cells from small intestine.
Topics: Animals; Calcium Channel Blockers; Carbachol; Cells, Cultured; Dose-Response Relationship, Drug; Dru | 1998 |
Human circular colonic smooth muscle cells possess active somatostatin receptors.
Topics: Aged; Carbachol; Cholecystokinin; Colon; Dose-Response Relationship, Drug; Female; Gastrointestinal | 1998 |
Involvement of different Ca2+ pools during the canine bronchial sustained contraction in Ca2+-free medium: lack of effect of PKC inhibition.
Topics: Animals; Bronchi; Bronchoconstriction; Calcium; Carbachol; Cardiotonic Agents; Dogs; Enzyme Inhibito | 1998 |
Tyrosine kinase inhibitors suppress prostaglandin F2alpha-induced phosphoinositide hydrolysis, Ca2+ elevation and contraction in iris sphincter smooth muscle.
Topics: Animals; Calcium; Carbachol; Cardiotonic Agents; Cats; Dinoprost; Dose-Response Relationship, Drug; | 1998 |
Potentiation by neurotensin of carbachol-induced tension development in beta-escin-skinned smooth muscle of guinea-pig ileum.
Topics: Animals; Bucladesine; Caffeine; Calcimycin; Calcium; Carbachol; Drug Synergism; Escin; Guinea Pigs; | 1998 |
Hypocapnia-induced contraction of porcine airway smooth muscle.
Topics: Animals; Bronchi; Bronchodilator Agents; Calcium; Calcium Channel Blockers; Carbachol; Carbon Dioxid | 1998 |
Effects of excess K+ on carbachol-induced contractions in the guinea-pig tracheal muscle.
Topics: Animals; Calcium; Calcium Channel Blockers; Carbachol; Drug Combinations; Guinea Pigs; Muscle Contra | 1998 |
Effect of calcium and calcium chelator on the response of the bladder to in vitro ischaemia.
Topics: Animals; Calcium; Carbachol; Chelating Agents; Dose-Response Relationship, Drug; Egtazic Acid; Free | 1998 |
In vitro functional evidence of neuronal cannabinoid CB1 receptors in human ileum.
Topics: Adult; Aged; Aged, 80 and over; Benzoxazines; Calcium Channel Blockers; Carbachol; Dose-Response Rel | 1998 |
Glicentin and oxyntomodulin modulate both the phosphoinositide and cyclic adenosine monophosphate signaling pathways in gastric myocytes.
Topics: Animals; Calcium; Carbachol; Colforsin; Cyclic AMP; Glicentin; Glucagon; Glucagon-Like Peptides; In | 1999 |
The effect of peroxynitrite on sphincter of Oddi motility.
Topics: Animals; Carbachol; Catalase; Electric Stimulation; Enzyme Inhibitors; Female; Gastrointestinal Moti | 1999 |
Correlation of EGTA and calcium-blocking agents on the response of the bladder to in vitro ischemia.
Topics: Animals; Calcium Channel Blockers; Carbachol; Chelating Agents; Diltiazem; Egtazic Acid; Electric St | 1999 |
Mechanical properties of lung parenchyma during bronchoconstriction.
Topics: Air Pressure; Airway Resistance; Algorithms; Animals; Bronchoconstriction; Carbachol; Elasticity; In | 1999 |
A direct inhibitory effect of erythromycin on rat urinary bladder smooth muscle.
Topics: Animals; Carbachol; Electric Stimulation; Erythromycin; In Vitro Techniques; Male; Muscarinic Agonis | 1999 |
Differences in contractile properties of anorectal smooth muscle and the effects of calcium channel blockade.
Topics: Adrenergic alpha-Antagonists; Anal Canal; Animals; Calcium Channel Blockers; Carbachol; Cholinergic | 1999 |
Enhanced sensitivity of the iris sphincter to the muscarinic agonist carbachol at lower temperature.
Topics: Animals; Atropine; Body Temperature; Carbachol; Cold Temperature; Dogs; Dose-Response Relationship, | 1999 |
Contractile and phosphatidylinositol responses of rat trachea to anticholinesterase drugs.
Topics: Animals; Carbachol; Cholinergic Agonists; Cholinesterase Inhibitors; Dimethylphenylpiperazinium Iodi | 1998 |
New N-(pyridin-4-yl)-(indol-3-yl)acetamides and propanamides as antiallergic agents.
Topics: Acetylcholine; Animals; Anti-Allergic Agents; Bronchoalveolar Lavage; Capillary Permeability; Carbac | 1999 |
M2 receptors in genito-urinary smooth muscle pathology.
Topics: Animals; Binding Sites; Carbachol; Diamines; Dose-Response Relationship, Drug; Female; Hypertrophy; | 1999 |
Diabetes abolishes the vascular protective effects of estrogen in female rats.
Topics: Animals; Aorta; Carbachol; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Enzyme | 1999 |
Erythromycin derivatives ABT 229 and GM 611 act on motilin receptors in the rabbit duodenum.
Topics: Animals; Anti-Bacterial Agents; Carbachol; Dose-Response Relationship, Drug; Duodenum; Erythromycin; | 1999 |
Urodynamics in acetone-induced cystitis of anesthetized rats.
Topics: Acetone; Administration, Intravesical; Animals; Atropine; Baclofen; Carbachol; Cystitis; Electric St | 1999 |
Different pathways for Ca2+ mobilization by angiotensin II and carbachol in the circular muscle of the guinea-pig ileum.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Calcium; Calcium Channel Blockers; Carbac | 1999 |
Effects of chronic unilateral internal pudendal arterial occlusion on reactivity of isolated corpus cavernosum strips from rabbits.
Topics: Adenosine; Animals; Arterial Occlusive Diseases; Arteries; Carbachol; Chronic Disease; Dose-Response | 1999 |
Pharmacological effects of tolterodine on human isolated urinary bladder.
Topics: Aged; Benzhydryl Compounds; Benzilates; Calcium Chloride; Carbachol; Cresols; Dose-Response Relation | 1999 |
Identification of SK-951, a novel benzofuran derivative, as an agonist to 5-HT4 receptors.
Topics: Acetylcholine; Animals; Benzofurans; Bridged Bicyclo Compounds, Heterocyclic; Carbachol; Cisapride; | 1999 |
Function of M3 muscarinic receptors in the rat urinary bladder following partial outlet obstruction.
Topics: Animals; Carbachol; Dose-Response Relationship, Drug; Male; Muscarinic Agonists; Muscarinic Antagoni | 1999 |
Evaluation of ureteric contraction: a comparison among ring, spiral-cut and longitudinal segments.
Topics: Animals; Biological Assay; Carbachol; Cholinergic Agonists; Dose-Response Relationship, Drug; Electr | 1999 |
Megacystis, mydriasis, and ion channel defect in mice lacking the alpha3 neuronal nicotinic acetylcholine receptor.
Topics: Animals; Carbachol; Disease Models, Animal; Electric Stimulation; Electrophysiology; Gene Targeting; | 1999 |
Distinct functional muscarinic receptors in guinea-pig gallbladder, ileum and atria.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Animals; Carbachol; Electric S | 1999 |
Relaxation of contracted rabbit tracheal and human bronchial smooth muscle by Y-27632 through inhibition of Ca2+ sensitization.
Topics: 1-Methyl-3-isobutylxanthine; Amides; Animals; Bronchi; Calcium; Carbachol; Cholinergic Agents; Deter | 1999 |
Mucosal modulation of agonist-induced myosin phosphorylation and contraction in airway smooth muscle.
Topics: Animals; Carbachol; Cattle; Cholinergic Agonists; Dose-Response Relationship, Drug; Mucous Membrane; | 1999 |
Is endogenous histamine involved in the contraction of the isolated trachea, evoked by muscarinic agonist?
Topics: Animals; Carbachol; Guinea Pigs; Histamine; Histamine Release; Mast Cells; Muscarinic Agonists; Musc | 1999 |
Age dependent response to exogenous estrogen on micturition, contractility and cholinergic receptors of the rat bladder.
Topics: Aging; Animals; Carbachol; Cholinergic Agonists; Dose-Response Relationship, Drug; Estrogens; Female | 1999 |
Pinacidil suppression on 5-HT3 receptor-mediated contraction of guinea pig ileum in vitro.
Topics: Animals; Carbachol; Guinea Pigs; Ileum; Male; Muscle Contraction; Muscle, Smooth; Myenteric Plexus; | 1998 |
Contractions in human detrusor smooth muscle induced by hypo-osmolar solutions.
Topics: Calcium Channel Blockers; Carbachol; Diltiazem; Dose-Response Relationship, Drug; Gadolinium; Humans | 1999 |
Tracheal relaxant activity of cissaglaberrimine and trilobinine, two aporphinic alkaloids from Cissampelos glaberrima.
Topics: Alkaloids; Animals; Brazil; Carbachol; Guinea Pigs; Histamine; In Vitro Techniques; Muscle Contracti | 1999 |
Distribution of active protein kinase C in smooth muscle.
Topics: Animals; Bufo marinus; Carbachol; Cytosol; Enzyme Activation; Image Processing, Computer-Assisted; I | 1999 |
The contribution of intracellular Ca2+ release to contraction in human bladder smooth muscle.
Topics: Calcium; Carbachol; Diltiazem; Humans; In Vitro Techniques; Muscle Contraction; Thapsigargin; Urinar | 1999 |
Cellular redistribution of PKCalpha, rhoA, and ROKalpha following smooth muscle agonist stimulation.
Topics: Animals; Calcium; Carbachol; Cell Membrane; Cells, Cultured; Cytoplasm; Female; GTP-Binding Proteins | 1999 |
The monoterpene alkaloid cantleyine from Strychnos trinervis root and its spasmolytic properties.
Topics: Alkaloids; Animals; Brazil; Carbachol; Female; Guinea Pigs; Histamine; Ileum; Male; Muscle Contracti | 1999 |
Isoeugenolol: a selective beta1-adrenergic antagonist with tracheal and vascular smooth muscle relaxant properties.
Topics: Adrenergic beta-1 Receptor Antagonists; Adrenergic beta-2 Receptor Antagonists; Adrenergic beta-Anta | 1999 |
Pharmacological characterization of beta-adrenoceptors mediating relaxation of the rat urinary bladder in vitro.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Carbachol; In Vitro Techniques; Isop | 1999 |
Mitochondrial clearance of cytosolic Ca(2+) in stimulated lizard motor nerve terminals proceeds without progressive elevation of mitochondrial matrix [Ca(2+)].
Topics: Action Potentials; Animals; Antimycin A; Axons; Caffeine; Calcium; Carbachol; Carbonyl Cyanide m-Chl | 1999 |
Relaxing action of sodium nitroprusside independent of membrane potential in the CCh-induced contracture of the guinea pig stomach muscle.
Topics: Animals; Carbachol; Charybdotoxin; Cholinergic Agonists; Cyclic GMP; Female; Gallopamil; Guanylate C | 1999 |
Lead generation using pharmacophore mapping and three-dimensional database searching: application to muscarinic M(3) receptor antagonists.
Topics: Animals; Carbachol; Guinea Pigs; In Vitro Techniques; Male; Models, Molecular; Muscarinic Antagonist | 1999 |
Abnormal response to cholinergic stimulation in the circular muscle layer of the human colon in diverticular disease.
Topics: Action Potentials; Carbachol; Cholinergic Agonists; Colon; Diverticulitis, Colonic; Electric Stimula | 1999 |
Carbachol-induced sustained tonic contraction of rat detrusor muscle.
Topics: Animals; Calcium; Calcium Channel Blockers; Carbachol; Female; Male; Muscle Contraction; Parasympath | 1999 |
Effects of in vivo ischemia on contractile responses of rabbit bladder to field stimulation, carbachol, ATP and KCl.
Topics: Adenosine Triphosphate; Animals; Carbachol; Electric Stimulation; Ischemia; Male; Muscle Contraction | 1999 |
Mechanisms underlying the inhibitory effect of propofol on the contraction of canine airway smooth muscle.
Topics: Anesthetics, Intravenous; Animals; Calcium; Carbachol; Dogs; Female; In Vitro Techniques; Inositol 1 | 1999 |
Age-related changes in muscarinic cholinoceptor function in guinea-pig and rat airways.
Topics: Acetylcholine; Aging; Animals; Carbachol; Cholinesterase Inhibitors; Cricetinae; Inositol Phosphates | 1999 |
A pharmacological examination of venom from the Papuan taipan (Oxyuranus scutellatus canni).
Topics: Acetophenones; Acetylcholine; Animals; Aorta; Blood Pressure; Carbachol; Chickens; Diaphragm; Dose-R | 1999 |
Pharmacological characterization of muscarinic receptors implicated in rabbit detrusor muscle contraction and activation of inositol phospholipid hydrolysis in rabbit detrusor and parotid gland.
Topics: Animals; Binding, Competitive; Carbachol; CHO Cells; Cricetinae; Dose-Response Relationship, Drug; F | 1999 |
A quantitative study of atropine-resistant contractile responses in human detrusor smooth muscle, from stable, unstable and obstructed bladders.
Topics: Adenosine Triphosphate; Atropine; Carbachol; Dose-Response Relationship, Drug; Drug Resistance; Fema | 1999 |
Muscarinic M(2) receptors are not primarily involved in the contraction of guinea-pig gallbladder smooth muscle.
Topics: Alkaloids; Animals; Benzodiazepines; Carbachol; Cevanes; Female; Gallamine Triethiodide; Gallbladder | 1999 |
Depolarization of membrane potential and the smooth muscle contraction by isothiocyanatobenzyl imidazoline in guinea-pig stomach circular muscle.
Topics: Animals; Atropine; Carbachol; Cromakalim; Dose-Response Relationship, Drug; Guinea Pigs; In Vitro Te | 1999 |
Evidence for a common defect associated with pressure in the aorta of two hypertensive rat strains.
Topics: Animals; Aorta, Thoracic; Carbachol; Dose-Response Relationship, Drug; Endothelium, Vascular; Hypert | 1999 |
Mechanical strain modulates maximal phosphatidylinositol turnover in airway smooth muscle.
Topics: Acetylcholine; Aluminum; Animals; Carbachol; Cattle; Cells, Cultured; Cholinergic Agonists; Fluorine | 1999 |
The effects of protein kinase C on trabecular meshwork and ciliary muscle contractility.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adult; Aged; Animals; Blotting, Western; Carbachol; C | 1999 |
Membrane ion channels as physiological targets for local Ca2+ signalling.
Topics: Animals; Calcium Signaling; Carbachol; Chloride Channels; Fluorescent Dyes; Guinea Pigs; Ileum; Male | 1999 |
Isolation of a muscarinic alkaloid with ocular hypotensive action from Trophis racemosa.
Topics: Acetylcholine; Alkaloids; Animals; Antihypertensive Agents; Atropine; Carbachol; Dogs; Female; Galla | 1999 |
Inhibitory effect of capsaicin on cholinergic transmission in ovine airways: evidence for non-cholinergic contractions.
Topics: Acetylcholine; Animals; Capsaicin; Carbachol; Dose-Response Relationship, Drug; Electric Stimulation | 1999 |
[Nphe(1)]nociceptin-(1-13)-NH(2) antagonizes nociceptin effects in the mouse colon.
Topics: Animals; Carbachol; Colon; Dose-Response Relationship, Drug; In Vitro Techniques; Male; Mice; Muscle | 1999 |
Characterization of the heat-released substance from rat ileal muscle.
Topics: Animals; Body Temperature; Carbachol; Cholinergic Agonists; Culture Media, Conditioned; Dose-Respons | 1999 |
Inhibition of Rho-associated kinase blocks agonist-induced Ca2+ sensitization of myosin phosphorylation and force in guinea-pig ileum.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Calcium; Carbachol; Cholinergic Agonists; En | 2000 |
Comparison of the effects of selective III, IV and nonselective phosphodiesterase inhibitors on isolated tracheal preparations in streptozotocin-diabetic rats.
Topics: Amrinone; Animals; Carbachol; Cardiotonic Agents; Diabetes Mellitus, Experimental; Dose-Response Rel | 2000 |
[Changes in isolated ciliary muscle caused by repeated instillation of carbachol ointment in rabbits and effect of topically applied amlexanox].
Topics: Administration, Topical; Aminopyridines; Animals; Carbachol; Cholinergic Agonists; Ciliary Body; In | 2000 |
Nociceptin inhibits tonic nitric oxide release in the mouse isolated proximal colon.
Topics: Animals; Carbachol; Colon; Excitatory Amino Acid Agonists; In Vitro Techniques; Male; Mice; Mice, In | 2000 |
In vitro contractile responses of detrusor to carbachol and neurokinin A, in children with recurrent urinary tract infection or day wetting.
Topics: Adolescent; Carbachol; Child; Child, Preschool; Cholinergic Agonists; Female; Humans; Infant; Male; | 2000 |
Increased intra-abdominal pressure alters the contractile properties of rabbit bladder.
Topics: Abdomen; Animals; Carbachol; Cholinergic Agonists; Electric Stimulation; Male; Muscle Contraction; P | 2000 |
Voltage-dependent inhibition of the muscarinic cationic current in guinea-pig ileal cells by SK&F 96365.
Topics: Animals; Calcium Channel Blockers; Carbachol; Guanosine 5'-O-(3-Thiotriphosphate); Guinea Pigs; Ileu | 2000 |
M(2) and M(4) receptor knockout mice: muscarinic receptor function in cardiac and smooth muscle in vitro.
Topics: Adenosine; Animals; Carbachol; Heart Rate; In Vitro Techniques; Male; Mice; Mice, Knockout; Muscle C | 2000 |
Simultaneous measures of contraction and intracellular calcium in single, cultured smooth muscle cells.
Topics: Animals; Calcium; Carbachol; Cells, Cultured; Chick Embryo; Muscarinic Agonists; Muscle Contraction; | 2000 |
Comparative physiology and biochemistry of rat and rabbit urinary bladder.
Topics: Adenosine Triphosphate; Animals; Carbachol; Electric Stimulation; Male; Muscle Contraction; Muscle, | 2000 |
Carbachol-induced sustained tonic contraction of rat detrusor muscle.
Topics: Animals; Carbachol; Miotics; Muscle Contraction; Rats; Urinary Bladder | 2000 |
Inhibition of the contractile response of the rat detrusor muscle by the beta(2)-adrenoceptor agonist clenbuterol.
Topics: Adenosine Triphosphate; Adrenergic beta-Agonists; Animals; Carbachol; Clenbuterol; Electric Stimulat | 2000 |
Functional and morphological modifications of the urinary bladder in aging female rats.
Topics: Adenosine Triphosphate; Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Aging; Animals; Arecoli | 2000 |
Resident macrophages activated by lipopolysaccharide suppress muscle tension and initiate inflammatory response in the gastrointestinal muscle layer.
Topics: Animals; Carbachol; Cell Movement; Dextrans; Digestive System; Enzyme Inhibitors; Female; Fluorescei | 2000 |
Effects of cannabinoid receptor agonists on neuronally-evoked contractions of urinary bladder tissues isolated from rat, mouse, pig, dog, monkey and human.
Topics: Acetylcholine; Adenosine Triphosphate; Animals; Atropine; Benzoxazines; Calcium Channel Blockers; Ca | 2000 |
The effects of cyclophosphamide on neurotransmission in the urinary bladder of Suncus murinus, the house musk shrew.
Topics: Adenosine Triphosphate; Animals; Antineoplastic Agents, Alkylating; Body Weight; Carbachol; Choliner | 2000 |
Mechanical strain memory in airway smooth muscle.
Topics: Animals; Biomechanical Phenomena; Carbachol; Cattle; In Vitro Techniques; Membrane Potentials; Muscl | 2000 |
Altered response to partial bladder outlet obstruction in mice lacking inducible nitric oxide synthase.
Topics: Animals; Carbachol; Cholinergic Agonists; Electric Stimulation; Female; In Vitro Techniques; Mice; M | 2000 |
Effect of inhibition of cyclooxygenase on pre- and postjunctional actions of peroxides in the iris-ciliary body.
Topics: Animals; Benzene Derivatives; Carbachol; Cattle; Cholinergic Agonists; Ciliary Body; Cyclooxygenase | 2000 |
Active properties of the urinary bladder: in vitro comparative studies between adult and neonatal rats.
Topics: Adenosine Triphosphate; Animals; Atropine; Carbachol; Dose-Response Relationship, Drug; In Vitro Tec | 2000 |
Effect of sodium butyric acid, sodium valerianic acid, and osmolarity on contractility of specimens of intestinal wall obtained from the cecum and spiral colon of healthy cows.
Topics: Animals; Butyric Acid; Carbachol; Cattle; Cattle Diseases; Cecum; Cholinergic Agonists; Colon; Cross | 2000 |
Responses of isolated normal human detrusor muscle to various spasmolytic drugs commonly used in the treatment of the overactive bladder.
Topics: Carbachol; Electric Stimulation; Humans; In Vitro Techniques; Muscarinic Agonists; Muscle Contractio | 2000 |
Relaxation of rat distal colon by activation of muscarinic, neuronal receptors: possible involvement of P(2y)-purinoceptors.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Animals; Carbachol; Colon; In | 2000 |
Leukaemia inhibitory factor (LIF) upregulates excitatory non-adrenergic non-cholinergic and maintains cholinergic neural function in tracheal explants.
Topics: Animals; Carbachol; Growth Inhibitors; Guinea Pigs; Interleukin-6; Leukemia Inhibitory Factor; Lymph | 2000 |
Cholinergic facilitation of neurotransmission to the smooth muscle of the guinea-pig prostate gland.
Topics: Acetylcholine; Animals; Carbachol; Cholinergic Agonists; Electric Stimulation; Guinea Pigs; Male; Mu | 2000 |
Inhibitory effects of muscarinic receptor autoantibodies on parasympathetic neurotransmission in Sjögren's syndrome.
Topics: Acetylcholine; Adult; Aged; Aged, 80 and over; Animals; Autoantibodies; Carbachol; Female; Humans; I | 2000 |
Possible site of action of TAK-637, a tachykinin NK(1) receptor antagonist, on the micturition reflex in guinea pigs.
Topics: Animals; Atropine; Benzhydryl Compounds; Benzilates; Carbachol; Cresols; Denervation; Dose-Response | 2000 |
Characterization of the effects of cannabinoids on guinea-pig tracheal smooth muscle tone: role in the modulation of acetylcholine release from parasympathetic nerves.
Topics: Acetylcholine; Analgesics; Analgesics, Non-Narcotic; Animals; Arachidonic Acids; Binding, Competitiv | 2000 |
Multiple functional defects in peripheral autonomic organs in mice lacking muscarinic acetylcholine receptor gene for the M3 subtype.
Topics: Animals; Body Weight; Carbachol; Digestive System; Digestive System Abnormalities; Female; Fertility | 2000 |
Functional characteristics of urinary tract smooth muscles in mice lacking cGMP protein kinase type I.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Carbachol; Cholinergic Agonists; Colforsin; Cyclic | 2000 |
The actions of metabolic inhibition on human detrusor smooth muscle contractility from stable and unstable bladders.
Topics: Adult; Calcium; Carbachol; Cell Hypoxia; Dose-Response Relationship, Drug; Humans; Middle Aged; Musc | 2000 |
Pharmacological and molecular analysis of ATP-sensitive K(+) channels in the pig and human detrusor.
Topics: Adenosine Triphosphate; Animals; Carbachol; Electric Stimulation; Female; Glyburide; Humans; Muscle | 2000 |
Sildenafil citrate on nitrergic transmission in anococcygeus muscles from the urogenital system of male and female mice.
Topics: Animals; Carbachol; Colforsin; Dose-Response Relationship, Drug; Female; In Vitro Techniques; Male; | 2000 |
Obstructive response of human bladder to BPH vs. rabbit bladder response to partial outlet obstruction: a direct comparison.
Topics: Adaptation, Physiological; Animals; Bethanechol; Calcium Signaling; Calcium-Transporting ATPases; Ca | 2000 |
Interaction between volatile anesthetics and hypoxia in porcine tracheal smooth muscle.
Topics: Analysis of Variance; Anesthetics, Inhalation; Animals; Calcium; Calcium Signaling; Carbachol; Chela | 2000 |
Nitrergic and purinergic regulation of the rat pylorus.
Topics: Adenosine Triphosphate; Animals; Carbachol; Electric Stimulation; Male; Muscle Contraction; Muscle, | 2000 |
The role of intracellular and extracellular calcium in mechanical and intracellular electrical activity of human urinary bladder smooth muscle.
Topics: Acetylcholine; Aged; Aged, 80 and over; Calcium; Carbachol; Electrophysiology; Extracellular Space; | 2000 |
Abnormal contractile properties of rectal smooth muscle in chronic ulcerative colitis.
Topics: Acetylcholinesterase; Carbachol; Cell Count; Chronic Disease; Colitis, Ulcerative; Histocytochemistr | 2000 |
Dual modulation by thrombin of the motility of rat oesophageal muscularis mucosae via two distinct protease-activated receptors (PARs): a novel role for PAR-4 as opposed to PAR-1.
Topics: Animals; Carbachol; Cholinergic Agents; Esophagus; Humans; In Vitro Techniques; Male; Muscle Contrac | 2000 |
Mitogen-activated protein kinase inhibitors suppress prostaglandin F(2alpha)-induced myosin-light chain phosphorylation and contraction in iris sphincter smooth muscle.
Topics: Animals; Carbachol; Cats; Dinoprost; Enzyme Inhibitors; Flavonoids; Imidazoles; Iris; Miotics; Mitog | 2000 |
Comparison of the effects of novel antimuscarinic drugs on human detrusor smooth muscle.
Topics: Aged; Benzhydryl Compounds; Carbachol; Cholinergic Antagonists; Cresols; Dose-Response Relationship, | 2000 |
Normal detrusor is more sensitive than hypertrophied detrusor to in vitro ischemia followed by re-oxygenation.
Topics: Animals; Carbachol; Electric Stimulation; Hypertrophy; Ischemia; Male; Muscle Contraction; Muscle, S | 2000 |
Spontaneous contractions of intestinal smooth muscle re-aggregates from the new-born rat triggered by thromboxane A2.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Animals, Newborn; Calci | 2000 |
Inhibition of small conductance K+ -channels attenuated melatonin-induced relaxation of serotonin-contracted rat gastric fundus.
Topics: Animals; Carbachol; Cholinergic Agonists; Electric Stimulation; Free Radical Scavengers; Gastric Fun | 2000 |
Mechanism of delayed gastric emptying in naturally occurring CCK-A receptor gene knockout (OLETF) rats.
Topics: Animals; Carbachol; Cholinergic Agonists; Gastric Emptying; Gene Expression; Male; Muscle Contractio | 2000 |
The role of M(2)-muscarinic receptors in mediating contraction of the pig urinary bladder in vitro.
Topics: Animals; Benzofurans; Binding, Competitive; Carbachol; Diamines; Dose-Response Relationship, Drug; F | 2000 |
P2X receptor expression in mouse urinary bladder and the requirement of P2X(1) receptors for functional P2X receptor responses in the mouse urinary bladder smooth muscle.
Topics: Adenosine Triphosphate; Animals; Atropine; Carbachol; Dose-Response Relationship, Drug; Electric Sti | 2000 |
Role of catalase in pre- and postjunctional responses of mammalian irides to hydrogen peroxide.
Topics: Amitrole; Animals; Carbachol; Catalase; Cattle; Female; Hydrogen Peroxide; In Vitro Techniques; Iris | 2000 |
Leukotriene C(4) enhances the contraction of porcine tracheal smooth muscle through the activation of Y-27632, a rho kinase inhibitor, sensitive pathway.
Topics: Amides; Animals; Calcium; Carbachol; Enzyme Inhibitors; Fluorescent Dyes; Fura-2; In Vitro Technique | 2001 |
Age-related changes in cholinergic and purinergic neurotransmission in human isolated bladder smooth muscles.
Topics: Adenosine Triphosphate; Aged; Aging; Atropine; Carbachol; Cholinergic Fibers; Drug Resistance; Elect | 2001 |
CLA reduces antigen-induced histamine and PGE(2) release from sensitized guinea pig tracheae.
Topics: Animals; Antigens; Carbachol; Dietary Fats; Dinoprostone; Eating; Female; Guinea Pigs; Histamine Rel | 2001 |
Modulation of nitrergic relaxant responses by peptides in the mouse gastric fundus.
Topics: Animals; Apamin; Carbachol; Cholinergic Agonists; Chymotrypsin; Electric Stimulation; Enzyme Inhibit | 2001 |
Inhibitory effects of amlexanox on carbachol-induced contractions of rabbit ciliary muscle and guinea-pig taenia caecum.
Topics: Aminopyridines; Animals; Anti-Allergic Agents; Calcium; Carbachol; Cecum; Cholinergic Agonists; Cili | 2000 |
M3 muscarinic receptors but not M2 mediate contraction of the porcine detrusor muscle in vitro.
Topics: Animals; Carbachol; Dose-Response Relationship, Drug; Female; In Vitro Techniques; Muscarinic Antago | 2000 |
Clonidine attenuates the carbachol-induced contractile and phosphatidylinositol responses of rat trachea.
Topics: Aluminum Compounds; Analgesics; Animals; Carbachol; Clonidine; Dose-Response Relationship, Drug; Flu | 2000 |
Muscarinic activation of transient inward current and contraction in canine colon circular smooth muscle cells.
Topics: Animals; Calcium; Carbachol; Colon; Dogs; Electric Stimulation; Electrophysiology; In Vitro Techniqu | 2001 |
Role of Ca2+ mobilization in muscarinic receptor-mediated membrane depolarization in guinea pig ileal smooth muscle cells.
Topics: Animals; Calcium; Calcium Channel Blockers; Calcium Channels; Carbachol; Cholinergic Agonists; Enzym | 2000 |
Muscarinic stimulation does not induce rhoA/ROCK-mediated Ca2+ sensitization of the contractile element in chicken gizzard smooth muscle.
Topics: Amides; Animals; Calcium; Carbachol; Chickens; Enzyme Inhibitors; Female; Gene Expression; Gizzard, | 2000 |
Control of vascular tone in notothenioid fishes is determined by phylogeny, not environmental temperature.
Topics: Animals; Antarctic Regions; Aorta; Arteries; Atropine; Blood Pressure; Body Temperature; Branchial R | 2001 |
Antigen-induced bronchial hyperreactivity and bronchopulmonary inflammation in rats: effect of TNF receptor binding protein.
Topics: Animals; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Bronchopneumonia; Carbachol; Carri | 2001 |
Inhibition of isolated rat and human detrusor muscle contraction by disopyramide.
Topics: Aged; Animals; Anti-Arrhythmia Agents; Atropine; Carbachol; Disopyramide; Electric Stimulation; Fema | 2000 |
Effect of the blood substitute diaspirin crosslinked hemoglobin in rat mesenteric and human radial collateral arteries.
Topics: Animals; Antihypertensive Agents; Arteries; Aspirin; Blood Substitutes; Bucladesine; Carbachol; Dose | 2001 |
The inhibitory effect of herbal medicine -Dai Kenchu To (DKT)- on the colonic motility in rats in vitro.
Topics: Animals; Carbachol; Colon; Culture Techniques; Dose-Response Relationship, Drug; Male; Muscle Contra | 2001 |
Effects of nitric oxide donors and nitric oxide synthase substrates on ciliary muscle contracted by carbachol and endothelin for possible use in myopia prevention.
Topics: Animals; Arginine; Canavanine; Carbachol; Cattle; Ciliary Body; Endothelin-1; Muscle Contraction; Mu | 2001 |
Effect of M2 and M3 muscarinic receptors on airway responsiveness to carbachol in bronchial-hypersensitive (BHS) and bronchial-hyposensitive (BHR) guinea pigs.
Topics: Animals; Bronchial Hyperreactivity; Carbachol; Diamines; Gene Expression; Guinea Pigs; Lung; Male; M | 2001 |
Bladder dysfunction after acute urinary retention in rats.
Topics: Acute Disease; Aldehydes; Animals; Blood Flow Velocity; Carbachol; In Vitro Techniques; Laser-Dopple | 2001 |
Effects of local anesthetics on the contractility of rat bladders.
Topics: Anesthetics, Local; Animals; Bupivacaine; Carbachol; Cholinergic Agonists; Female; Lidocaine; Male; | 2001 |
Mechanical response to electrical field stimulation of rat, guinea-pig, monkey and human detrusor muscle: a comparative study.
Topics: Aged; Animals; Atropine; Carbachol; Chlorocebus aethiops; Cholinergic Agonists; Electric Stimulation | 2001 |
Differential alterations in tachykinin NK2 receptors in isolated colonic circular smooth muscle in inflammatory bowel disease and idiopathic chronic constipation.
Topics: Adult; Aged; Aged, 80 and over; Carbachol; Cholinergic Agonists; Chronic Disease; Colon; Constipatio | 2001 |
Investigations into the physiological role of muscarinic M2 and M4 muscarinic and M4 receptor subtypes using receptor knockout mice.
Topics: Animals; Carbachol; Cerebral Cortex; Heart; Heart Rate; Humans; Hypothermia; Male; Mice; Mice, Knock | 2001 |
The mechanism for the contraction induced by leukotriene C4 in guinea-pig taenia coli.
Topics: Animals; Calcium; Calcium Channel Blockers; Carbachol; Cardiotonic Agents; Chelating Agents; Colon; | 2001 |
Disturbance of the prejunctional modulation of cholinergic neurotransmission during chronic granulomatous inflammation of the mouse ileum.
Topics: Adrenergic Agonists; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; | 2001 |
The in vitro pharmacological profile of prucalopride, a novel enterokinetic compound.
Topics: Acetylcholine; Animals; Benzofurans; Binding, Competitive; Carbachol; Cell Line; CHO Cells; Colon; C | 2001 |
Effects of protein kinase inhibitor, HA1077, on intraocular pressure and outflow facility in rabbit eyes.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Actins; Animals; Aqueous Humor; Blotting, Western; Ca | 2001 |
Pharmacological characterization of muscarinic receptors in mouse isolated urinary bladder smooth muscle.
Topics: Acetylcholine; Animals; Carbachol; Diamines; Dioxolanes; Dose-Response Relationship, Drug; In Vitro | 2001 |
Role of ovarian hormones in the pathogenesis of impaired detrusor contractility: evidence in ovariectomized rodents.
Topics: Animals; Axons; Carbachol; Cholinergic Agonists; Estrogens; Female; Muscle Contraction; Muscle, Smoo | 2001 |
Muscarinic excitation-contraction coupling mechanisms in tracheal and bronchial smooth muscles.
Topics: Animals; Bronchi; Bronchial Hyperreactivity; Calcium; Calcium-Transporting ATPases; Carbachol; Chlor | 2001 |
There is no direct relationship between PI response and smooth muscle contraction of rat trachea stimulated by alpha-agonists.
Topics: Adrenergic alpha-Agonists; Animals; Carbachol; In Vitro Techniques; Inositol Phosphates; Muscle Cont | 2001 |
Phospholamban regulation of bladder contractility: evidence from gene-altered mouse models.
Topics: Animals; Blotting, Western; Calcium; Calcium-Binding Proteins; Carbachol; Down-Regulation; In Vitro | 2001 |
Mechanism of a nitric oxide donor NOR 1-induced relaxation in longitudinal muscle of rat proximal colon.
Topics: Animals; Calcium; Carbachol; Colon; Culture Techniques; Cyclic GMP; DNA-Binding Proteins; Dose-Respo | 2001 |
Reduction of intraocular pressure by topical administration of an inhibitor of the Rho-associated protein kinase.
Topics: Administration, Topical; Amides; Animals; Antihypertensive Agents; Carbachol; Ciliary Body; Enzyme I | 2001 |
Colitis-induced alterations in adrenergic control of circular smooth muscle in vitro in rats.
Topics: Adrenergic Agonists; Adrenergic Antagonists; Animals; Carbachol; Colitis; Disease Progression; Elect | 2001 |
Dai-kenchu-to enhances accelerated small intestinal movement.
Topics: Acetylcholine; Animals; Carbachol; Dose-Response Relationship, Drug; Electric Stimulation; Gastroint | 2001 |
Action of tacrine on muscarinic receptors in rat intestinal smooth muscle.
Topics: Acetylcholine; Animals; Carbachol; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Duod | 2001 |
On the functional role of muscarinic M2 receptors in cholinergic and purinergic responses in the rat urinary bladder.
Topics: 2-Chloroadenosine; Adenosine; Adenosine Triphosphate; Animals; Carbachol; Diamines; Dose-Response Re | 2001 |
Inhibition by clonidine of the carbachol-induced tension development and nonselective cationic current in guinea pig ileal myocytes.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Calcium Channels; Carbachol; Cloni | 2001 |
Mechanisms of action of unoprostone on trabecular meshwork contractility.
Topics: Adult; Aged; Animals; Antihypertensive Agents; Calcium; Carbachol; Cattle; Cells, Cultured; Choliner | 2001 |
The role of the L-type Ca(2+) channel in refilling functional intracellular Ca(2+) stores in guinea-pig detrusor smooth muscle.
Topics: Animals; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium-Transporting ATPases; | 2002 |
Urothelium derived inhibitory factor and cross-talk among receptors in the trigone of the bladder of the pig.
Topics: Animals; Biological Factors; Carbachol; Histamine; In Vitro Techniques; Muscle Contraction; Muscle, | 2002 |
Role of IL-4, IL-13, and STAT6 in inflammation-induced hypercontractility of murine smooth muscle cells.
Topics: Animals; Carbachol; CD3 Complex; Cholinergic Agonists; Dose-Response Relationship, Drug; Gastrointes | 2002 |
Origin of Ca2+ necessary for carbachol-induced contraction in longitudinal muscle of the proximal colon of rats.
Topics: Aminobenzoates; Animals; Caffeine; Calcium; Calcium Channel Blockers; Carbachol; Chlorobenzoates; Ci | 2001 |
Increased smooth muscle contractility of intestine in the genetic null of the endothelin ETB receptor: a rat model for long segment Hirschsprung's disease.
Topics: Animals; Carbachol; Cholinergic Agonists; Disease Models, Animal; Dose-Response Relationship, Drug; | 2002 |
Functional effects of dextran sulphate sodium (DSS) treatment on the longitudinal muscle of rat distal colon.
Topics: Animals; Carbachol; Cholinergic Agonists; Colitis; Colon; Dextran Sulfate; Dose-Response Relationshi | 2001 |
Effect of doxazosin on rat urinary bladder function after partial outlet obstruction.
Topics: Adenosine Triphosphate; Administration, Oral; Adrenergic alpha-Antagonists; Animals; Blood Flow Velo | 2002 |
Glutamate mediated responses in isolated trachea preparations from control and ovalbumin sensitized guinea-pigs.
Topics: 2-Amino-5-phosphonovalerate; Animals; Carbachol; Dose-Response Relationship, Drug; Electric Stimulat | 2002 |
Spasmolytic effects of three harmala alkaloids on guinea-pig isolated trachea.
Topics: Adrenergic beta-Antagonists; Alkaloids; Animals; Binding, Competitive; Calcium Channels; Carbachol; | 2001 |
Two classes of endothelin receptors mediating contraction in esophageal muscularis mucosae.
Topics: Animals; Atropine; Autoradiography; Azepines; Binding, Competitive; Carbachol; Cell Membrane; Cells, | 2002 |
M(3)-receptor knockout mice: muscarinic receptor function in atria, stomach fundus, urinary bladder, and trachea.
Topics: Animals; Atrial Function; Body Weight; Carbachol; Cardiotonic Agents; Cholinergic Agonists; Gastric | 2002 |
Muscarinic receptor knockout mice: role of muscarinic acetylcholine receptors M(2), M(3), and M(4) in carbamylcholine-induced gallbladder contractility.
Topics: Animals; Anti-Arrhythmia Agents; Atropine; Carbachol; Cardiovascular Agents; Cholinesterase Inhibito | 2002 |
Agonist-induced phasic and tonic responses in smooth muscle are mediated by InsP(3).
Topics: Animals; Caffeine; Calcium; Carbachol; Colon; Electrophysiology; Guinea Pigs; In Vitro Techniques; I | 2002 |
Direct inhibitory effect of erythromycin on human alimentary tract smooth muscle.
Topics: Carbachol; Colon; Electric Stimulation; Erythromycin; Gallbladder; Gastrointestinal Agents; Gastroin | 2002 |
Effects of nimesulide and pentoxifylline on decreased contractile responses in rat ileum with peritonitis.
Topics: Animals; Carbachol; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Enzyme Inhibitors; | 2002 |
In vitro evaluation of motilin agonism by macrolide immunosuppressive drugs.
Topics: Animals; Carbachol; Cyclosporine; Duodenum; Electric Stimulation; Erythromycin; Immunosuppressive Ag | 2002 |
Effect of preservation conditions on autonomic transmission in rat small bowel.
Topics: Adenosine Triphosphate; Animals; Atropine; Autonomic Nervous System; Carbachol; Female; Intestine, S | 2002 |
Sensitization of enteric reflexes in the rat colon in vitro.
Topics: Animals; Area Under Curve; Carbachol; Cholinergic Agonists; Colon; Cyclooxygenase Inhibitors; Dose-R | 2002 |
Effect of L-NAME on decreased ileal muscle contractility induced by peritonitis in rats.
Topics: Animals; Carbachol; Dose-Response Relationship, Drug; Gastrointestinal Motility; Ileum; Male; Muscle | 2002 |
Effects of papaya seed extract and benzyl isothiocyanate on vascular contraction.
Topics: Animals; Calcium; Carbachol; Cardiotonic Agents; Carica; Carotid Arteries; Cattle; Cells, Cultured; | 2002 |
Purification and characterization of a neurotoxin from the venom of Ophiophagus hannah (king cobra).
Topics: Amino Acid Sequence; Animals; Carbachol; Cardiotonic Agents; Chromatography, High Pressure Liquid; C | 2002 |
O-Substituted derivatives of pralidoxime: muscarinic properties and protection against soman effects in rats.
Topics: Acetylcholinesterase; Animals; Atropine; Binding, Competitive; Blood Pressure; Brain; Carbachol; Cho | 2002 |
Action of six commonly used benzodiazepines on isolated guinea-pig ileum preparation.
Topics: Animals; Anti-Anxiety Agents; Barium; Benzodiazepines; Carbachol; Guinea Pigs; Ileum; In Vitro Techn | 1975 |
Anticholinergic activity of antipsychotic drugs in relation to their extrapyramidal effects.
Topics: Animals; Antipsychotic Agents; Atropine; Carbachol; Extrapyramidal Tracts; Female; Guinea Pigs; In V | 1976 |
Effects of stimulant and relaxant drugs on tension and cyclic nucleotide levels in canine femoral artery.
Topics: Animals; Carbachol; Central Nervous System Stimulants; Cyclic AMP; Cyclic GMP; Dogs; Femoral Artery; | 1976 |
Studies on the mode of antagonism between adrenergic beta-mimetics and beta-blocking agents (III). Functional antagonism between beta-mimetics and spasmogens.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Carbachol; Dibenzylchlorethamine; Dr | 1976 |
Studies on the mode of antagonism between adrenergic beta-mimetics and beta-blocking agents (IV). Influence of functional antagonism by spasmogens.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Binding, Competitive; Carbachol; His | 1976 |
Actions of the muscle relaxant chandonium iodide on guinea-pig ileum and vas deferens preparations.
Topics: Acetylcholine; Androstenes; Animals; Carbachol; Electric Stimulation; Guinea Pigs; Histamine; Ileum; | 1976 |
Kinetic analysis of the AH8165-receptor interaction at the mammalian neuromuscular junction.
Topics: Animals; Carbachol; Dose-Response Relationship, Drug; Electric Stimulation; Guinea Pigs; Kinetics; M | 1977 |
Effects of carbachol and calcium on the cyclic guanosine-3',5'-monophosphate (cyclic GMP) metabolism in intestinal smooth muscle.
Topics: Animals; Calcium; Carbachol; Colon; Cyclic AMP; Cyclic GMP; Guanylate Cyclase; Microsomes; Muscle Co | 1977 |
Regulation of adenosine cyclic 3',5'-monophosphate and guanosine cyclic 3',5'-monophosphate levels and contractility in bovine tracheal smooth muscle.
Topics: Animals; Calcium; Carbachol; Cattle; Cyclic AMP; Cyclic GMP; Enzyme Activation; Guanylate Cyclase; H | 1977 |
The use of functional antagonism to determine whether beta-adrenoceptor agonists must have a lower efficacy than isoprenaline to be trachea-atria selective in vitro in guinea-pigs.
Topics: Adrenergic beta-Agonists; Animals; Carbachol; Female; Guinea Pigs; Heart; Heart Atria; Heart Rate; I | 1977 |
Desensitization of human bronchial smooth muscle to beta-receptor agonists.
Topics: Adrenergic beta-Agonists; Aminophylline; Bronchi; Carbachol; Drug Resistance; Electric Stimulation; | 1977 |
Atypical (relaxant) response to histamine in cat bronchus.
Topics: Airway Resistance; Animals; Bronchi; Burimamide; Carbachol; Cats; Female; Histamine; Histamine H1 An | 1977 |
Local anesthetic contracture and relaxation of airway smooth muscle.
Topics: Aminobenzoates; Anesthetics, Local; Animals; Bronchodilator Agents; Bupivacaine; Carbachol; Guinea P | 1977 |
Regulation of guanosine 3',5'-cyclic monophosphate levels and contractility in rat myometrium.
Topics: Animals; Calcium; Carbachol; Cyclic AMP; Cyclic GMP; Enzyme Activation; Female; Guanylate Cyclase; H | 1978 |
The presence of inhibitory histamine H-2-receptors in guinea-pig tracheobronchial muscle.
Topics: Animals; Bronchi; Carbachol; Female; Guinea Pigs; Histamine; In Vitro Techniques; Male; Methylhistam | 1978 |
The relationship between cholinesterase inhibition in the chick biventer cervicis muscle and its sensitivity to exogenous acetylcholine.
Topics: Acetylcholine; Animals; Carbachol; Chickens; Cholinesterase Inhibitors; In Vitro Techniques; Kinetic | 1978 |
Effects of some autonomic drugs on duodenal smooth muscle.
Topics: Acetylcholine; Adrenergic Agonists; Animals; Bethanechol Compounds; Carbachol; Duodenum; Female; Iso | 1979 |
The reversal by pyridostigmine of neuromuscular block produced by soman.
Topics: Acetylcholine; Acetylcholinesterase; Animals; Carbachol; In Vitro Techniques; Male; Muscle Contracti | 1979 |
Responses of guinea-pig lung parenchymal strips to prostaglandins and some selected autacoids.
Topics: Animals; Autacoids; Bradykinin; Carbachol; Epinephrine; Female; Guinea Pigs; Histamine; In Vitro Tec | 1979 |
Possible existence of "spare" beta-receptors in rat tracheal smooth muscle.
Topics: Adrenergic beta-Antagonists; Affinity Labels; Animals; Carbachol; Ethylenediamines; Female; In Vitro | 1979 |
Effects of trimetaquinol on equine pulmonary vascular and airway smooth muscle.
Topics: Airway Resistance; Animals; Carbachol; Histamine; Horses; Humans; In Vitro Techniques; Isoquinolines | 1979 |
Calcium source for contractile response of guinea pig taenia caecum to carbachol in a calcium deficient, potassium rich solution.
Topics: Animals; Calcium; Carbachol; Cecum; Drug Synergism; Egtazic Acid; Female; Guinea Pigs; Histamine; In | 1978 |
Pharmacologic characterization of isolated rhesus monkey bronchial smooth muscle.
Topics: Acetylcholine; Animals; Atropine; Bronchi; Bronchodilator Agents; Carbachol; Dose-Response Relations | 1979 |
[Pharmacological analysis of the inhibition of peristalsis of the isolated guinea-pig ileum by tetramethylammonium].
Topics: Acetylcholine; Animals; Arecoline; Carbachol; Female; Gastrointestinal Motility; Guinea Pigs; Histam | 1976 |
Cimetidine fails to block functional antagonism of carbachol by histamine in rat trachea.
Topics: Airway Resistance; Animals; Carbachol; Cimetidine; Guanidines; Histamine Antagonists; In Vitro Techn | 1979 |
Cyclic nucleotides and the contraction of smooth muscle.
Topics: Animals; Atropine; Calcium; Carbachol; Cattle; Colon; Cyclic AMP; Cyclic GMP; Diethylstilbestrol; Gu | 1975 |
Comparison of the effects of general anesthethics on the end-plate of skeletal muscle.
Topics: Anesthesia, General; Anesthetics; Animals; Anura; Carbachol; Dose-Response Relationship, Drug; Guine | 1975 |
An analysis of the mode of action of carbachol on the chick biventer cervicis nerve--muscle preparation.
Topics: Acetylcholine; Animals; Bungarotoxins; Calcium; Carbachol; Chickens; Cholinesterase Inhibitors; Dose | 1976 |
Cyclic nucleotide levels during carbachol-induced smooth muscle contractions.
Topics: Animals; Carbachol; Cyclic AMP; Cyclic GMP; Female; Guinea Pigs; Ileum; Kinetics; Male; Methacholine | 1976 |
Differentiation of intestinal smooth muscle relaxation caused by drugs that inhibit phosphodiesterase.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Aminophylline; Ammonium Chloride; Animals; Calcium; Carbachol; | 1976 |
The actions of three diaminopyridines on the chick biventer cervicis muscle.
Topics: Acetylcholine; Animals; Bungarotoxins; Caffeine; Calcimycin; Carbachol; Chickens; Convulsants; Elect | 1977 |
Changes of airway smooth muscle in experimental asthma.
Topics: Animals; Asthma; Carbachol; Dose-Response Relationship, Drug; Guinea Pigs; Histamine; Male; Muscle C | 1978 |
Studies on beta-adrenoceptors mediating changes in mechanical events and adenosine 3',5'-monophosphate levels. Guinea-pig trachea.
Topics: Animals; Calcium; Carbachol; Cyclic AMP; Ethanolamines; Female; Guinea Pigs; In Vitro Techniques; Is | 1978 |
Sensitivity to cyclic nucleotides and to aspirin of the kininogen-consuming system activated by adrenaline or carbamylcholine in rat blood.
Topics: Animals; Aspirin; Carbachol; Cyclic AMP; Cyclic GMP; Epinephrine; Kininogens; Kinins; Male; Muscle C | 1978 |
Interaction of prostaglandins and adenosine 5'-triphosphate in the noncholinergic neurotransmission in rabbit detrusor.
Topics: Adenosine Triphosphate; Animals; Carbachol; Dose-Response Relationship, Drug; Drug Interactions; Fem | 1978 |
Beta-adrenoceptor stimulation and cyclic AMP levels in bovine tracheal muscle of old and young animals.
Topics: Acetylcholine; Age Factors; Animals; Carbachol; Cattle; Cyclic AMP; Histamine; Isoproterenol; Muscle | 1978 |
alpha And beta-adrenoceptors in the detrusor muscle and bladder base of the pig and beta-adrenoceptors in the detrusor muscle of man.
Topics: Adult; Aged; Albuterol; Animals; Butoxamine; Carbachol; Female; Humans; In Vitro Techniques; Male; M | 1979 |
Differences in purity of commercial samples of hemicholinium-3: effects on high affinity choline uptake, neuromuscular transmission, acetylcholinesterase and carbachol and acetylcholine contractions.
Topics: Acetylcholine; Animals; Carbachol; Cattle; Chickens; Choline; Cholinesterase Inhibitors; Drug Contam | 1979 |
Pharmacological properties of n1-piperonyl-n4-3,7,11-trimethyl-2,6,10-dodecatrienyl-piperazine, a new non-anticholinergic gastric antisecretory agent.
Topics: Animals; Carbachol; Central Nervous System; Depression, Chemical; Dogs; Feeding Behavior; Female; Ga | 1975 |
Excitatory actions of GABA and of acetyl-choline in sea urchin tube feet.
Topics: Acetylcholine; Aminobutyrates; Atropine; Butyrylthiocholine; Carbachol; Chlorides; Decamethonium Com | 1975 |
On the use of functional antagonism to estimate dissociation constants for beta adrenergic receptor agonists in isolated guinea-pig trachea.
Topics: Adrenergic beta-Agonists; Animals; Carbachol; Dose-Response Relationship, Drug; Ethanolamines; Femal | 1975 |
Effect of potassium on the mechanical activity of taenia coli, uterus and portal vein of the guinea-pig.
Topics: Animals; Carbachol; Cold Temperature; Colon; Dose-Response Relationship, Drug; Female; Guinea Pigs; | 1978 |
Recovery of acetylcholine response of denervated muscle following exposure to alpha-bungarotoxin.
Topics: Acetylcholine; Animals; Anura; Bungarotoxins; Carbachol; Hexamethonium Compounds; In Vitro Technique | 1978 |
Pharmacological studies on N-demethylated carbachol.
Topics: Animals; Anura; Atropine; Blood Pressure; Carbachol; Cats; Chickens; Dealkylation; Dogs; Female; Gan | 1978 |
Mode of action of quinacrine on the acetylcholine receptor ionic channel complex.
Topics: Acetylcholine; Animals; Anura; Carbachol; Female; Fishes; In Vitro Techniques; Ion Channels; Membran | 1979 |
The effect of hydrolytic enzymes on the acetylcholine sensitivity of the skeletal muscle cell membrane.
Topics: Acetylcholine; Animals; Bungarotoxins; Carbachol; Drug Interactions; Edrophonium; Hydrolases; In Vit | 1978 |
Detection of contraction of isolated smooth muscle cells in suspension.
Topics: Animals; Bufo marinus; Carbachol; Muscle Contraction; Muscle, Smooth; Stomach | 1977 |
Characteristics of response of isolated smooth muscle cells to cholinergic drugs.
Topics: Acetylcholine; Animals; Atropine; Bufo marinus; Carbachol; Dose-Response Relationship, Drug; Electri | 1977 |
Excitation-contraction coupling in multiunit tracheal smooth muscle during metabolic depletion: induction of rhythmicity.
Topics: Acetylcholine; Adenosine Triphosphate; Animals; Calcium; Carbachol; Dogs; Egtazic Acid; Gallopamil; | 1977 |
Prostaglandins and tetrodotoxin-insensitive relaxation of opossum lower esophageal sphincter.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Action Potentials; Animals; Black Widow Spider; Carbachol; Esophago | 1979 |
Role of glucose in contractility of airway smooth muscle.
Topics: Acetylcholine; Animals; Carbachol; Glucose; Guinea Pigs; Histamine; In Vitro Techniques; Muscle Cont | 1979 |
Comparison of the urinary bladder base and detrusor to cholinergic and histaminergic receptor activation in the rabbit.
Topics: Animals; Atropine; Carbachol; Histamine; Male; Muscle Contraction; Muscle, Smooth; Pyrilamine; Rabbi | 1979 |
Mianserin potentiates responses to acetylcholine in the rat anococcygeus muscle.
Topics: Acetylcholine; Animals; Carbachol; Dibenzazepines; Drug Synergism; Hydroxydopamines; In Vitro Techni | 1979 |
Pharmacological characterization of the rabbit lung strip.
Topics: Airway Resistance; Animals; Bradykinin; Carbachol; Epinephrine; Female; Histamine; In Vitro Techniqu | 1979 |
The affinity of atropine for muscarine receptors in human sphincter pupillae.
Topics: Atropine; Carbachol; Humans; In Vitro Techniques; Iris; Kinetics; Muscle Contraction; Muscle, Smooth | 1979 |
Prostaglandin generation by human and guinea pig lung tissue: comparison of parenchymal and airway responses.
Topics: Anaphylaxis; Animals; Carbachol; Guinea Pigs; Histamine; Humans; Lung; Muscle Contraction; Muscle, S | 1979 |
Coronary anaphylaxis in vitro.
Topics: Anaphylaxis; Animals; Atropine; Carbachol; Cattle; Coronary Vessels; Histamine; In Vitro Techniques; | 1979 |
Pharmacological evaluation of the lung strip of neonatal swine.
Topics: Animals; Animals, Newborn; Carbachol; Female; Histamine; Indomethacin; Isoproterenol; Lung; Male; Mu | 1979 |
Increased phosphatidate accumulation during single contractions of isolated smooth-muscle cells [proceedings].
Topics: Animals; Carbachol; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; Phosphates; Phosphatidi | 1979 |
The action of acetylcholine and catecholamines on an intracellular calcium store in the smooth muscle cells of the guinea-pig taenia coli.
Topics: Acetylcholine; Animals; Calcium; Carbachol; Colon; Dose-Response Relationship, Drug; Guinea Pigs; In | 1979 |
Intracellular sodium and carbachol contractions in the guinea-pig taenia coli [proceedings].
Topics: Animals; Carbachol; Colon; Guinea Pigs; Muscle Contraction; Muscle, Smooth; Sodium | 1979 |
An alteration in sensitivity to cholinergic agents on guinea-pig ilea and atria after repeated administration of an organophosphate and an antagonism by a carbamate.
Topics: Acetylcholine; Animals; Carbachol; Carbamates; Cholinesterases; Drug Interactions; Guinea Pigs; Ileu | 1979 |
Noradrenergic supersensitivity in the rat vas deferens during barbital withdrawal.
Topics: Animals; Barbital; Barbiturates; Carbachol; Humans; In Vitro Techniques; Male; Muscle Contraction; M | 1977 |
Hypertrophic smooth muscle. IV. Myofilaments, intermediate filaments and some mechanical properties.
Topics: Animals; Carbachol; Cell Survival; Cytoskeleton; Guinea Pigs; Hypertrophy; Ileum; Muscle Contraction | 1979 |
Biochemical studies on muscarinic receptors.
Topics: Acetylcholine; Alkylating Agents; Animals; Atropine; Binding, Competitive; Brain; Carbachol; Cattle; | 1977 |
[Functional studies of the cardia muscles in achalasia].
Topics: Acetylcholine; Carbachol; Cardia; Esophageal Achalasia; Humans; Muscle Contraction; Muscle, Smooth | 1977 |
Postoperative gastrointestinal electrical and mechanical activities in a patient with idiopathic intestinal pseudoobstruction.
Topics: Acetylcholine; Action Potentials; Atropine; Bethanechol Compounds; Carbachol; Electric Stimulation; | 1978 |
[Impairment of adrenergic innervation in achalasia (author's transl)].
Topics: Acetylcholine; Carbachol; Cardia; Dose-Response Relationship, Drug; Epinephrine; Esophageal Achalasi | 1978 |
Structure-activity relationships for the anticholinoceptor action of tricyclic antidepressants.
Topics: Acetylcholine; Animals; Antidepressive Agents, Tricyclic; Carbachol; Guinea Pigs; In Vitro Technique | 1978 |
Pharmacological and biochemical properties of isomeric yohimbine alkaloids.
Topics: Animals; Brain; Carbachol; Cholinesterase Inhibitors; Hypothalamus; In Vitro Techniques; Male; Mice; | 1978 |
Comparative responses of tracheal spirals and parenchymal strips to histamine and carbachol in vitro.
Topics: Acetylcholine; Airway Resistance; Animals; Carbachol; Drug Interactions; Guinea Pigs; Histamine; In | 1978 |
Light-induced calcium release in a photosensitive vertebrate smooth muscle.
Topics: Animals; Calcium; Carbachol; Cricetinae; Dark Adaptation; In Vitro Techniques; Iris; Light; Mesocric | 1978 |
Reactivity of isolated bovine cerebral arteries to biogenic amines.
Topics: Acetylcholine; Animals; Biogenic Amines; Carbachol; Cattle; Cerebral Arteries; Histamine; In Vitro T | 1978 |
Effect of stretch and contraction on caveolae of smooth muscle cells.
Topics: Animals; Carbachol; Colon; Freeze Fracturing; Guinea Pigs; Male; Muscle Contraction; Muscle Relaxati | 1978 |
Properties of contractions induced by ouabain and K+-free solution in guinea pig taenia coli.
Topics: Animals; Calcium; Carbachol; Chlorides; Colon; Guinea Pigs; Histamine; In Vitro Techniques; Male; Mu | 1978 |
Physiological and pharmacological studies on isolated human bronchial preparations.
Topics: Acetylcholine; Aged; Albuterol; Bronchi; Carbachol; Dose-Response Relationship, Drug; Electric Stimu | 1978 |
Effects of nifedipine on the smooth muscle of the human urinary tract in vitro and in vivo.
Topics: Administration, Oral; Adult; Aged; Carbachol; Chlorides; Female; Humans; Male; Middle Aged; Muscle C | 1978 |
[Pharmacological studies on supersensitization (IV). Site and mode of action of cocaine to potentiate acetylcholine in isolated tracheal preparation of rat (author's transl)].
Topics: Acetylcholine; Animals; Atropine; Calcium; Carbachol; Cocaine; Dose-Response Relationship, Drug; Dru | 1978 |
Atropine blockade of cholinergic drugs on rabbit stomach muscle.
Topics: Animals; Atropine; Carbachol; Dibenzylchlorethamine; In Vitro Techniques; Muscle Contraction; Muscle | 1978 |
Modulation of the prostaglandin-induced intestinal motility in humans through the transmitters of the vegetative nervous system.
Topics: Acetylcholine; Atropine; Carbachol; Colon; Epinephrine; Gastrointestinal Motility; Humans; Muscle Co | 1978 |
Potentiation of nerve-induced bladder responses by tetraethylammonium in relation to junctional and extrajunctional muscarinic receptors.
Topics: Animals; Atropine; Botulinum Toxins; Carbachol; In Vitro Techniques; Male; Muscle Contraction; Neuro | 1978 |
Release of [3H-noradrenaline from the motor adrenergic nerves of the anococcygeus muscle by lysergic acid diethylamide, tyramine or nerve stimulation.
Topics: Animals; Carbachol; Cats; Cocaine; Electric Stimulation; In Vitro Techniques; Lysergic Acid Diethyla | 1978 |
Carbachol-induced sensitivity changes in skeletal muscle and their mechanism of action.
Topics: Acetylcholine; Animals; Anura; Calcium; Carbachol; Hexamethonium Compounds; In Vitro Techniques; Mus | 1978 |
The effect of beta-agonists and of K+-depolarization on an intracellular Ca store in smooth muscle of guinea-pig taenia coli [proceedings].
Topics: Animals; Calcium; Carbachol; Colon; Guinea Pigs; In Vitro Techniques; Intracellular Fluid; Isoproter | 1978 |
[Diphasic course of the curve of contraction of isolated intestine produced by massive doses of drugs. I. Effect of calcium].
Topics: Acetylcholine; Animals; Calcium; Carbachol; Dose-Response Relationship, Drug; Guinea Pigs; Histamine | 1978 |
Contraction of isolated smooth muscle cells by inophore A23187.
Topics: Animals; Anti-Bacterial Agents; Biological Transport; Bufo marinus; Calcimycin; Calcium; Carbachol; | 1975 |
Comparison of drug-induced responses of rabbit trachea and bronchus.
Topics: Aminophylline; Animals; Atropine; Bronchi; Carbachol; Dose-Response Relationship, Drug; Female; Hist | 1976 |
Increase in resting tension of tracheal muscle due to rigor during metabolic inhibition.
Topics: Adenosine Triphosphate; Animals; Carbachol; Dogs; Egtazic Acid; Female; Glucose; Glycogen; In Vitro | 1976 |
Comparison of arteries with longitudinal and circular venous muscle from the rat.
Topics: Amino Acids; Angiotensin II; Animals; Aorta; Arteries; Carbachol; Cocaine; Dose-Response Relationshi | 1977 |
Effects of antidepressant drugs on noradrenaline accumulation and contractile responses in the rat anococcygeus muscle.
Topics: Acetylcholine; Animals; Antidepressive Agents; Carbachol; Chromatography, Thin Layer; Depression, Ch | 1977 |
Antimuscarinic and noncompetitive antagonist properties of dicyclomine hydrochloride in isolated human and rabbit bladder muscle.
Topics: Animals; Atropine; Carbachol; Cyclohexanecarboxylic Acids; Dicyclomine; Dose-Response Relationship, | 1977 |
The effect of 5-hydroxytryptamine on the chick biventer cervicis muscle.
Topics: Acetylcholine; Animals; Carbachol; Chickens; Cholinesterases; Creatinine; Electric Stimulation; In V | 1977 |
Morphine-induced supersensitivity to acetylcholine in skeletal muscle and its mechanism of action.
Topics: Acetylcholine; Animals; Anura; Calcium; Carbachol; Drug Synergism; In Vitro Techniques; Morphine; Mu | 1977 |
Characterization of autonomic receptors in the smooth musculature of human Graafian follicle.
Topics: Acetylcholine; Adult; Atropine; Autonomic Nervous System; Carbachol; Cocaine; Epinephrine; Female; H | 1977 |
Isometric and isotonic contractions in airway smooth muscle.
Topics: Animals; Carbachol; Dogs; Electric Stimulation; In Vitro Techniques; Muscle Contraction; Muscle Tonu | 1977 |
[Repeated contractions: conditioning and memory of the organ].
Topics: Animals; Carbachol; Guinea Pigs; Intestines; Memory; Muscle Contraction; Muscle, Smooth; Temperature | 1977 |
Endogenous prostaglandins and mechanical tension in canine trachealis muscle.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Aspirin; Atropine; Carbachol; Dogs; Indomethacin; Membrane | 1976 |
Effects of dipyridamole on the smooth muscle cells of the guinea-pig's taenia coli.
Topics: Adenosine Triphosphate; Animals; Carbachol; Cell Membrane; Colon; Dipyridamole; Electric Conductivit | 1976 |
Vas deferens desensitization by noradrenaline and other drugs.
Topics: Acetylcholine; Animals; Barium; Carbachol; Cocaine; Denervation; Hydroxydopamines; Imipramine; In Vi | 1976 |
Uptake and release of catecholamines in sympathetic nerve fibres in the spleen of the cod, Gadus morhua.
Topics: Amphetamine; Animals; Carbachol; Catecholamines; Cocaine; Denervation; Desipramine; Electric Stimula | 1976 |
Uptake and release of catecholamines in sympathetic nerve fibers in the spleen of the cod, Gadus morhua.
Topics: Acetylcholine; Animals; Benzenaminium, 4,4'-(3-oxo-1,5-pentanediyl)bis(N,N-dimethyl-N-2-propenyl-), | 1976 |
Effects of ketamine on the peripheral autonomic nervous system of the rat.
Topics: Animals; Autonomic Fibers, Postganglionic; Autonomic Fibers, Preganglionic; Autonomic Nervous System | 1976 |
Factors determining the potency of mydriatic drugs in man.
Topics: Administration, Topical; Adult; Amides; Animals; Atropine; Carbachol; Choline; Cyclopentolate; Dose- | 1976 |
The adrenergic innervation and adrenergic receptor activity of the feline urinary bladder and urethra in the normal state and after hypogastric and/or parasympathetic denervation.
Topics: Animals; Carbachol; Cats; Denervation; Female; Histocytochemistry; Hypogastric Plexus; Isoproterenol | 1976 |
Investigation of the relationship between cell-surface calcium-ion gating and phosphatidylinositol turnover by comparison of the effects of elevated extracellular potassium ion concentration on ileium smooth muscle and pancreas.
Topics: Animals; Atropine; Calcium; Carbachol; Cell Membrane; Guinea Pigs; Ileum; Muscle Contraction; Muscle | 1976 |
Studies on the loss of sensitivity in smooth muscle.
Topics: Acetylcholine; Animals; Carbachol; Desensitization, Immunologic; Guinea Pigs; Histamine; Muscle Cont | 1976 |
Influence of extracellular calcium and a water-soluble carboxyl group reagent on cholinergic drug-receptor interactions in skeletal muscle.
Topics: Animals; Anura; Calcium; Calcium Chloride; Carbachol; Carbodiimides; Decamethonium Compounds; Ethyld | 1975 |
Isotonic and isometric responses of different tonic muscles to agonists and antagonists.
Topics: Acetylcholine; Alkylating Agents; Animals; Carbachol; Cholinesterase Inhibitors; Guinea Pigs; Holoth | 1976 |
Effect of ionophore X-537A on desensitization rate and tension development in potassium-depolarized muscle fibres.
Topics: Animals; Anti-Bacterial Agents; Calcium; Carbachol; Dose-Response Relationship, Drug; Drug Synergism | 1976 |
Comparative responses of the isolated human testicular capsule to autonomic drugs.
Topics: Acetylcholine; Aged; Autonomic Agents; Barium; Carbachol; Chlorides; Humans; Male; Middle Aged; Musc | 1975 |
Dual action of chloroquine on frog's skeletal muscle contraction.
Topics: Acetylcholine; Animals; Caffeine; Carbachol; Chloroquine; Cholinesterase Inhibitors; Cholinesterases | 1975 |
The irreversible binding of acetylcholine mustard to muscarinic receptors in intestinal smooth muscle of the guinea-pig.
Topics: Acetylcholine; Animals; Carbachol; Guinea Pigs; In Vitro Techniques; Intestinal Mucosa; Muscle Contr | 1975 |
Muscarinic receptors in rat intestinal muscle: comparison with the guinea pig.
Topics: Animals; Atropine; Aziridines; Benzilates; Carbachol; Choline; Guinea Pigs; In Vitro Techniques; Int | 1975 |
Alteration of esophageal peristalsis by pentagastrin in patients with diffuse esophageal spasm.
Topics: Carbachol; Esophageal Achalasia; Esophagogastric Junction; Esophagus; Humans; Middle Aged; Muscle Co | 1975 |
The effect of methyl paraben on tracheal smooth muscle in vitro.
Topics: Animals; Bronchodilator Agents; Carbachol; Guinea Pigs; Heart Atria; In Vitro Techniques; Intestines | 1975 |
[Effect of somatostatin on betazole-stimulated gastric secretion and carbachol-stimulated pancreatic secretion and gall bladder contraction in man(author's transl)].
Topics: Adult; Betazole; Carbachol; Female; Gallbladder; Gastric Juice; Gastric Mucosa; Humans; Male; Muscle | 1975 |
Further experimental evidence for a smooth muscle depressant effect of ketamine.
Topics: Acetylcholine; Animals; Barium; Carbachol; Depression, Chemical; Female; Guinea Pigs; Histamine; Ile | 1975 |
Desensitization in the innervated and in the chronically denervated soleus muscle of the mouse.
Topics: Acetylcholine; Animals; Caffeine; Carbachol; Denervation; In Vitro Techniques; Male; Mice; Muscle Co | 1975 |
A comparison of the potencies of a series of barbiturates at the neuromuscular junction and on the central nervous system.
Topics: Animals; Barbiturates; Carbachol; Central Nervous System; Depression, Chemical; Guinea Pigs; In Vitr | 1975 |
Some differences in contractile responses of isolated longitudinal and circular muscle from the guinea-pig stomach.
Topics: Animals; Calcium; Carbachol; Electric Stimulation; Guinea Pigs; In Vitro Techniques; Membrane Potent | 1975 |
Proceedings: Is the latency of parasympathetic nerve effects due to a slow activation of muscarinic receptors? An iontophoretic study.
Topics: Animals; Carbachol; Guinea Pigs; In Vitro Techniques; Iontophoresis; Membrane Potentials; Muscle Con | 1975 |
Autonomic nerves mediating contractility in the human graafian follicle.
Topics: Atropine; Autonomic Nervous System; Carbachol; Dibenzylchlorethamine; Dose-Response Relationship, Dr | 1975 |
Potentiating effects of C-terminal octapeptide of cholecystokinin on contractility of isolated guinea-pig gallbladder.
Topics: Acetylcholine; Animals; Carbachol; Cholecystokinin; Female; Gallbladder; Guinea Pigs; Muscle Contrac | 1975 |
In vitro measurement of margin of safety of neuromuscular transmission.
Topics: Animals; Carbachol; Dose-Response Relationship, Drug; Electrophysiology; Guinea Pigs; Mathematics; M | 1975 |
Some pharmacological properties of the cremaster muscle of the guinea-pig.
Topics: Acetylcholine; Animals; Atropine; Carbachol; Electric Stimulation; Epinephrine; Guinea Pigs; Histami | 1975 |
The effects of cocaine and diphenhydramine upon the reactivity of rat vas deferens to supramaximal doses of noradrenaline and of other agonists: the mode of action of cocaine.
Topics: Acetylcholine; Animals; Carbachol; Cocaine; Diphenhydramine; Drug Interactions; Electric Stimulation | 1976 |
Endogenous prostaglandin in guinea pig taenia coli.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Action Potentials; Animals; Aspirin; Atropine; Carbachol; Colon; Do | 1976 |
The effect of external calcium and magnesium ions on the response of denervated muscle to acetylcholine.
Topics: Acetylcholine; Animals; Calcium; Carbachol; In Vitro Techniques; Magnesium; Membrane Potentials; Mus | 1976 |
Altered tracheal smooth muscle activities in an animal model of human myotonic dystrophy.
Topics: Animals; Carbachol; Cholesterol; Diazonium Compounds; Dibenzylchlorethamine; Disease Models, Animal; | 1976 |
Pharmacological aspects of neuromuscular transmission in the thymus deficient nude (Nu/Nu) mouse.
Topics: Acetylcholine; Animals; Carbachol; Cholinesterases; Dose-Response Relationship, Drug; Mice; Mice, Nu | 1976 |
Mechanisms of neurotensin-induced inhibition in rat ileal smooth muscle.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1992 |
A pharmacological study of NK1 and NK2 tachykinin receptor characteristics in the rat isolated urinary bladder.
Topics: Animals; Carbachol; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Neurokinin A; Neu | 1992 |
Clinical potency of calcium channel blockers in asthma may be related to their inhibition of receptor-mediated phasic responses in vitro.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1992 |
[Functional evaluation of possible cytokine receptors on airway smooth muscle: modification of airway smooth muscle responses by cytokines].
Topics: Animals; Carbachol; Guinea Pigs; In Vitro Techniques; Interferon-gamma; Interleukin-2; Isoproterenol | 1992 |
Inhibitory role of gamma-amino-butyric acid in the rabbit urinary bladder.
Topics: Animals; Baclofen; Bicuculline; Carbachol; Depression, Chemical; Dose-Response Relationship, Drug; G | 1992 |
Effects of Ro 5-4864 and PK 11195 in rat duodenum and vas deferens.
Topics: Animals; Benzodiazepinones; Calcium; Carbachol; Cholera Toxin; Duodenum; In Vitro Techniques; Isoqui | 1992 |
Effects of isoproterenol and forskolin on carbachol- and fluoroaluminate-induced polyphosphoinositide hydrolysis, inositol trisphosphate production, and contraction in bovine iris sphincter smooth muscle: interaction between cAMP and IP3 second messenger
Topics: Aluminum; Animals; Carbachol; Cattle; Colforsin; Cyclic AMP; Deferoxamine; Fluorine; Hydrolysis; Ino | 1992 |
Characterization of CGRP receptor sites in rat airways.
Topics: Animals; Calcitonin Gene-Related Peptide; Carbachol; Dose-Response Relationship, Drug; In Vitro Tech | 1992 |
Receptor-operated calcium-channels in isolated rabbit jejunum.
Topics: Animals; Calcium Channel Blockers; Calcium Channels; Carbachol; Dose-Response Relationship, Drug; In | 1992 |
Carbachol stimulates adenylate cyclase and phospholipase C and muscle contraction-relaxation in a reciprocal manner in dog iris sphincter smooth muscle.
Topics: Adenylyl Cyclases; Animals; Calcium; Calmodulin; Carbachol; Cats; Cattle; Cyclic AMP; Dogs; Inositol | 1992 |
Mechanism of relaxing action of the antiasthmatic drug, azelastine, in isolated porcine tracheal smooth muscle.
Topics: Animals; Bronchodilator Agents; Carbachol; Cyclic AMP; Cyclic GMP; Endothelins; Muscle Contraction; | 1992 |
The inhibitory action of cyclic AMP on responses to carbachol dependent on calcium stores in rat gastric smooth muscle.
Topics: Animals; Bucladesine; Caffeine; Calcium; Carbachol; Cyclic AMP; Inositol 1,4,5-Trisphosphate; Muscle | 1992 |
Effects of PAF on excitatory neuro-effector transmission in dog airways.
Topics: Acetylcholine; Animals; Benzoquinones; Bronchi; Carbachol; Dogs; Electric Stimulation; Female; In Vi | 1992 |
(+/-)-CP-96,345, a selective tachykinin NK1 receptor antagonist, has non-specific actions on neurotransmission.
Topics: Animals; Biphenyl Compounds; Carbachol; Dinoprost; Electric Stimulation; Female; Guinea Pigs; Hypnot | 1992 |
Regional differences of the contractile responses to acetylcholine and neurokinin A in rabbit airway: heterogeneous distribution of the metabolic enzymes.
Topics: Acetylcholine; Acetylcholinesterase; Animals; Bronchi; Carbachol; In Vitro Techniques; Male; Muscle | 1992 |
Possible mechanisms of action of the antispasmodic agent tiropramide in the isolated detrusor from rats.
Topics: Animals; Calcium; Carbachol; Colforsin; Cyclic AMP; Cytosol; Fura-2; In Vitro Techniques; Male; Musc | 1992 |
Actions of somatostatins on gastric smooth muscle cells.
Topics: Amino Acid Sequence; Animals; Bucladesine; Carbachol; Cyclic AMP; Dose-Response Relationship, Drug; | 1992 |
Formoterol, fenoterol, and salbutamol as partial agonists for relaxation of maximally contracted guinea pig tracheae: comparison of relaxation with receptor binding.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Albuterol; Animals; Binding, Competitive; Carbachol; Cu | 1992 |
Contractions induced by phenylephrine and noradrenaline are differently affected by endothelium-dependent relaxation in rat aorta.
Topics: Animals; Carbachol; Endothelium, Vascular; In Vitro Techniques; Male; Muscle Contraction; Muscle Rel | 1992 |
Characterization of muscarinic receptors that mediate contraction of guinea-pig isolated trachea to choline esters: effect of removing epithelium.
Topics: Acetylcholine; Animals; Bethanechol; Bethanechol Compounds; Carbachol; Dose-Response Relationship, D | 1992 |
Effects of the calcium antagonists diltiazem, verapamil and nitrendipine on the contractile responses of guinea-pig isolated ileum to electrical stimulation or carbachol.
Topics: Animals; Carbachol; Diltiazem; Electric Stimulation; Enkephalin, Methionine; Guinea Pigs; Ileum; In | 1992 |
Effects of vasoactive intestinal peptide (VIP) on contractile responses of smooth muscle in rat stomach.
Topics: Animals; Caffeine; Calcium; Carbachol; Female; In Vitro Techniques; Male; Muscle Contraction; Muscle | 1991 |
Increased levels of substance P in the myenteric plexus of Trichinella-infected rats.
Topics: Animals; Capsaicin; Carbachol; Male; Muscle Contraction; Myenteric Plexus; Peroxidase; Rats; Rats, I | 1992 |
Responses of isolated Japanese monkey tracheal muscle to allergic mediators.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Allergens; Animals; Carbachol; H | 1992 |
Carbachol modulates voltage sensitivity of calcium channels in bronchial smooth muscle of rats.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1992 |
Endothelium-dependent relaxation to acetylcholine in the rabbit basilar artery: importance of membrane hyperpolarization.
Topics: Acetylcholine; Amino Acid Oxidoreductases; Animals; Arginine; Atropine; Basilar Artery; Carbachol; E | 1992 |
Extracellular matrix regulates smooth muscle responses to substance P.
Topics: Amnion; Animals; Basement Membrane; Carbachol; Cells, Cultured; Chick Embryo; Extracellular Matrix; | 1992 |
Effect of compounds from Mandevilla velutina on bradykinin-mediated contractile and relaxant responses of the isolated guinea pig trachea.
Topics: Animals; Bradykinin; Carbachol; Dinoprost; Epithelial Cells; Epithelium; Female; Guinea Pigs; Histam | 1992 |
Impairment of contractile response to carbachol and muscarinic receptor coupling in gastric antral smooth muscle cells isolated from diabetic streptozotocin-treated rats and db/db mice.
Topics: Animals; Carbachol; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Disease Models, Anim | 1992 |
Evidence for the presence of regional differences in the calcium antagonist receptors in lower urinary tract smooth muscle.
Topics: Animals; Binding Sites; Calcium Channel Blockers; Carbachol; Dihydropyridines; Drug Interactions; Fe | 1992 |
Purinoceptors mediating relaxation and spasm in the rat gastric fundus.
Topics: Adenosine Triphosphate; Animals; Carbachol; Gastric Fundus; In Vitro Techniques; Male; Muscle Contra | 1992 |
Decreased sensitivity of muscarinic but not 5-hydroxytryptamine receptors of the internal anal sphincter in neurogenic faecal incontinence.
Topics: Adult; Aged; Aged, 80 and over; Anal Canal; Carbachol; Fecal Incontinence; Female; Humans; Middle Ag | 1992 |
Evaluation of airway smooth muscle contractions in vitro by high-frequency ultrasonic imaging.
Topics: Acetylcholine; Animals; Bronchi; Carbachol; Dose-Response Relationship, Drug; Humans; In Vitro Techn | 1992 |
Effect of calcium antagonists (omega-conotoxin GVIA, verapamil, gallopamil, diltiazem) on bronchial smooth muscle contractions induced by soman.
Topics: Acetylcholinesterase; Animals; Bronchi; Butyrylcholinesterase; Calcium Channel Blockers; Carbachol; | 1992 |
[The effect of ecdysterone on carbachol contracture of ureteral smooth muscle and Mg2+,ATP-dependent transport of Ca2+ through the sarcolemma].
Topics: Adenosine Triphosphate; Animals; Biological Transport; Calcium; Carbachol; Cations, Divalent; Contra | 1992 |
The direct effects of diethylstilboestrol and nifedipine on the contractile responses of isolated human and rat detrusor muscles.
Topics: Acetylcholine; Animals; Carbachol; Diethylstilbestrol; Electric Stimulation; Female; Humans; In Vitr | 1992 |
Differential sensitivity to bradykinin of esophageal distension-sensitive mechanoreceptors in vagal and sympathetic afferents of the opossum.
Topics: Action Potentials; Afferent Pathways; Animals; Axons; Bradykinin; Carbachol; Esophagus; Mechanorecep | 1992 |
Comparison of urinary bladder function in 6 and 24 month male and female rats.
Topics: Adenosine Triphosphate; Aging; Animals; Carbachol; Collagen; Female; In Vitro Techniques; Male; Musc | 1992 |
On the pharmacological and physiological role of glibenclamide-sensitive potassium channels in colonic smooth muscle.
Topics: Animals; Benzopyrans; Carbachol; Colforsin; Colon; Cromakalim; Dogs; Drug Interactions; Electric Sti | 1992 |
Effects of phorbol ester on lower urinary tract smooth muscles in rabbits.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Carbachol; Drug Interactions; Female; Isoqui | 1992 |
Increased contraction and inositol phosphate formation of tracheal smooth muscle from hyperresponsive guinea pigs.
Topics: Animals; Carbachol; Dose-Response Relationship, Drug; Guinea Pigs; Histamine; Inositol Phosphates; M | 1992 |
Increased sensitivity of guinea pig gallbladder in vitro to bradykinin.
Topics: Animals; Bradykinin; Carbachol; Cycloheximide; Gallbladder; Guinea Pigs; In Vitro Techniques; Indome | 1992 |
Effects of vasoactive intestinal polypeptide on isolated rat urinary bladder smooth muscle.
Topics: Acetylcholine; Animals; Carbachol; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Ra | 1992 |
An investigation of some S-nitrosothiols, and of hydroxy-arginine, on the mouse anococcygeus.
Topics: Animals; Antimetabolites; Arginine; Autonomic Nervous System; Carbachol; Cold Temperature; Hemoglobi | 1992 |
The effect of in vivo oestrogen pretreatment on the contractile response of rat isolated detrusor muscle.
Topics: Acetylcholine; Animals; Atropine; Carbachol; Electric Stimulation; Estradiol; Female; In Vitro Techn | 1992 |
Iron-sulphur cluster nitrosyls, a novel class of nitric oxide generator: mechanism of vasodilator action on rat isolated tail artery.
Topics: Animals; Arteries; Carbachol; Chemical Phenomena; Chemistry, Physical; In Vitro Techniques; Iron Che | 1992 |
[Morphological and physiological change in the dis-used bladder of hemodialysis patients].
Topics: Adolescent; Adult; Atrophy; Carbachol; Compliance; Depression, Chemical; Dose-Response Relationship, | 1992 |
Mechanism of soman-induced contractions in canine tracheal smooth muscle.
Topics: Acetylcholine; Animals; Carbachol; Cholinesterase Inhibitors; Dogs; Drug Synergism; Electric Stimula | 1992 |
The M3 muscarinic receptor links to three different transduction mechanisms with different efficacies in circular muscle of guinea-pig stomach.
Topics: Animals; Carbachol; Female; Gallamine Triethiodide; Gastric Fundus; Guinea Pigs; In Vitro Techniques | 1992 |
Calcium ion-independent contraction of bladder smooth muscle.
Topics: Animals; Caffeine; Calcium; Carbachol; Humans; In Vitro Techniques; Muscle Contraction; Muscle, Smoo | 1992 |
The influence of ovariectomy and estradiol replacement on urinary bladder function in rats.
Topics: Adenosine Triphosphate; Animals; Body Weight; Carbachol; Estradiol; Estrogen Replacement Therapy; Fe | 1992 |
Urinary bladder function in rats with hereditary diabetes insipidus; a cystometrical and in vitro evaluation.
Topics: Animals; Carbachol; Diabetes Insipidus; Diuresis; Electric Stimulation; Female; Heterozygote; Homozy | 1992 |
Comparison of contractile mechanisms by carbachol and ATP in detrusor strips of rabbit urinary bladder.
Topics: Adenosine Triphosphate; Animals; Calcium; Carbachol; Cyclooxygenase Inhibitors; In Vitro Techniques; | 1992 |
Excitability of canine colon circular muscle disconnected from the network of interstitial cells of Cajal.
Topics: Animals; Barium; Barium Compounds; Carbachol; Chlorides; Colon; Dogs; Electric Stimulation; Female; | 1992 |
Direct inhibitory effect of calcitonin gene-related peptide and atrial natriuretic peptide on gastric smooth muscle cells via different mechanisms.
Topics: Animals; Atrial Natriuretic Factor; Calcitonin Gene-Related Peptide; Carbachol; Didanosine; Guinea P | 1992 |
The influence of streptozotocin-induced diabetes mellitus on the sensitivity of rat urinary bladder body and base strips to changes in extracellular calcium.
Topics: Animals; Calcium; Carbachol; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Male | 1992 |
Yersinia enterocolitica enteritis affects rabbit intestinal longitudinal smooth muscle function.
Topics: Animals; Carbachol; Dose-Response Relationship, Drug; Enteritis; Intestines; Muscle Contraction; Mus | 1992 |
Endothelin-1 stimulates phosphatidylinositol hydrolysis in the iris/ciliary complex and is a potent constrictor of the sphincter muscle.
Topics: Animals; Atropine; Carbachol; Ciliary Body; Dose-Response Relationship, Drug; Endothelins; Hydrolysi | 1992 |
Muscarinic receptor subtype specificity of (N,N-dialkylamino)alkyl 2-cyclohexyl-2-phenylpropionates: cylexphenes (cyclohexyl-substituted aprophen analogues).
Topics: Acetylcholine; alpha-Amylases; Animals; Binding, Competitive; Carbachol; Cyclohexanes; Guinea Pigs; | 1992 |
Nitric oxide mediates the neural nonadrenergic, noncholinergic relaxation of pig tracheal smooth muscle.
Topics: Animals; Arginine; Carbachol; Electric Stimulation; Muscle Contraction; Muscle, Smooth; Nervous Syst | 1992 |
The inhibitory effects of cromakalim and its active enantiomer BRL 38227 against various agonists in guinea pig and human airways: comparison with pinacidil and verapamil.
Topics: Animals; Benzopyrans; Bronchi; Bronchial Spasm; Bronchodilator Agents; Carbachol; Cromakalim; Drug I | 1992 |
Phasic responses to carbachol in isolated guinea pig trachea are augmented by cooling and inhibited by nifedipine.
Topics: Animals; Carbachol; Cold Temperature; Guinea Pigs; Kinetics; Male; Muscle Contraction; Muscle, Smoot | 1992 |
Purinergic and cholinergic contractions in adult and neonatal rabbit bladder.
Topics: Acetylcholine; Adenosine Triphosphate; Animals; Animals, Newborn; Atropine; Carbachol; In Vitro Tech | 1992 |
Endothelin-1-induced [3H]-inositol phosphate accumulation in rat trachea.
Topics: Animals; Carbachol; Endothelins; In Vitro Techniques; Inositol Phosphates; Male; Muscle Contraction; | 1992 |
Regulation of the Ca2+ dependence of smooth muscle contraction.
Topics: Animals; Calcium; Carbachol; Cations, Divalent; Cattle; In Vitro Techniques; Isoproterenol; Membrane | 1992 |
Evaluation of UW solution for preservation of small intestinal transplants in the rat.
Topics: Acetylcholine; Adenosine; Allopurinol; Animals; Carbachol; Glutathione; Insulin; Intestine, Small; M | 1992 |
Smooth muscle relaxation and inhibition of responses to pinacidil and cromakalim induced by phentolamine in guinea-pig isolated trachea.
Topics: Animals; Benzopyrans; Carbachol; Cromakalim; Dinoprost; Female; Guanidines; Guinea Pigs; Histamine; | 1992 |
Neuraminidase reduces the number of super-high-affinity [3H]oxotremorine-M binding sites in lung.
Topics: Animals; Carbachol; Clostridium perfringens; Guinea Pigs; In Vitro Techniques; Kinetics; Lung; Male; | 1992 |
A pharmacological in vitro study of the mouse urinary bladder at the time of acute change in bladder reservoir function after irradiation.
Topics: Acetylcholine; Animals; Carbachol; Electric Stimulation; Guanidines; In Vitro Techniques; Indomethac | 1992 |
Impairment of contractility associated with muscarinic supersensitivity in trachea isolated from diabetic rats: lack of correlation with ultrastructural changes or quinuclidinyl benzylate binding to lung membranes.
Topics: Animals; Carbachol; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Lung; Male; Muscle Contr | 1992 |
Acute desensitization of muscarinic receptors in the isolated guinea-pig ileal longitudinal muscle.
Topics: Animals; Carbachol; Dose-Response Relationship, Drug; Guinea Pigs; Ileum; In Vitro Techniques; Male; | 1992 |
Haloperidol differentiates smooth muscle contractions induced by release of intracellularly stored Ca and by influx of extracellular Ca.
Topics: Animals; Caffeine; Calcium; Carbachol; Female; Guinea Pigs; Haloperidol; Histamine; In Vitro Techniq | 1992 |
Neuropeptide release from the isolated, perfused, lower esophageal sphincter region of the rabbit and the effect of vasoactive intestinal peptide on the sphincter.
Topics: Animals; Carbachol; Drug Combinations; Esophagogastric Junction; In Vitro Techniques; Muscle Contrac | 1992 |
T-lymphocyte modulation of intestinal muscle function in the Trichinella-infected rat.
Topics: Analysis of Variance; Animals; Carbachol; Cell Division; Concanavalin A; Disease Models, Animal; Int | 1991 |
In vitro contractile responses of vasa deferentia from spontaneously diabetic BB rats.
Topics: Animals; Blood Glucose; Body Weight; Calcium Channels; Carbachol; Diabetes Mellitus, Experimental; E | 1991 |
Binding affinity and antimuscarinic activity of sigma and phencyclidine receptor ligands.
Topics: Animals; Binding, Competitive; Carbachol; Cerebral Cortex; Dioxolanes; Guinea Pigs; Haloperidol; Ile | 1991 |
Endogenously formed leukotriene C4 activates LTC4 receptors in guinea pig tracheal strips.
Topics: Acetophenones; Animals; Antimetabolites; Benzyl Compounds; Carbachol; Guinea Pigs; Hydroxamic Acids; | 1991 |
Effect of extracellular Ca2+ on cholinergic, KCl and phorbol ester-mediated phosphoinositide turnover and guinea pig urinary bladder contraction.
Topics: Animals; Calcium; Carbachol; Enzyme Activation; Guinea Pigs; In Vitro Techniques; Male; Muscle Contr | 1991 |
Effects of age on muscarinic agonist-induced contraction and IP accumulation in airway smooth muscle.
Topics: Aging; Animals; Carbachol; GTP-Binding Proteins; Guinea Pigs; Inositol Phosphates; Male; Muscle Cont | 1991 |
Muscarinic receptor stimulation of phosphoinositide hydrolysis in the human isolated urinary bladder.
Topics: Acetylcholine; Adult; Aged; Aged, 80 and over; Atropine; Carbachol; Female; Humans; Hydrolysis; In V | 1991 |
The effect of M & B 22948 on carbachol-induced inositol trisphosphate accumulation and contraction in iris sphincter smooth muscle.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Carbachol; Cattle; Hydrolysis; Inositol 1,4,5-Trisphos | 1991 |
Maturational regulation of inositol 1,4,5-trisphosphate metabolism in rabbit airway smooth muscle.
Topics: Animals; Calcium; Calmodulin; Carbachol; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Inositol | 1991 |
On the mechanism of spontaneous recovery of neuromuscular transmission after acetylcholinesterase inhibition in the rat neuromuscular junction.
Topics: Animals; Carbachol; Cholinesterase Inhibitors; Diaphragm; Electric Stimulation; Electrophysiology; I | 1991 |
Action of acetylcholine on smooth muscle.
Topics: Acetylcholine; Animals; Calcium; Calcium Channels; Carbachol; Chloride Channels; Intestine, Small; M | 1991 |
The mechanism of LTE4-induced histamine hyperresponsiveness in guinea-pig tracheal and human bronchial smooth muscle, in vitro.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Aged; Animals; Atropine; Bipheny | 1991 |
Effect of respiratory tract viral infection on murine airway beta-adrenoceptor function, distribution and density.
Topics: Animals; Autoradiography; Carbachol; Chick Embryo; In Vitro Techniques; Influenza A virus; Iodine Ra | 1991 |
Investigation of the antihistaminic action of dimethindene maleate (Fenistil) and its optical isomers.
Topics: Animals; Atrial Function; Carbachol; Cell Membrane; Cerebral Cortex; Dimethindene; Dose-Response Rel | 1991 |
Inhibition of peptidases potentiates enkephalin-stimulated contraction of gastric muscle cells.
Topics: Aminopeptidases; Animals; Anti-Bacterial Agents; Carbachol; CD13 Antigens; Enkephalin, Leucine; Enke | 1991 |
Dicentrine, a natural vascular alpha 1-adrenoceptor antagonist, isolated from Lindera megaphylla.
Topics: Adrenergic alpha-Antagonists; Animals; Aorta, Thoracic; Aporphines; Carbachol; Female; Guinea Pigs; | 1991 |
Modulatory effect of insulin on rat small intestinal motility and peptide release in vitro.
Topics: Animals; Bombesin; Carbachol; Dose-Response Relationship, Drug; Electric Stimulation; Gastrointestin | 1991 |
Muscarinic supersensitivity in the rat urinary bladder after capsaicin pretreatment.
Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Carbachol; Electric Stimulation; Female; Immuno | 1990 |
Phorbol esters inhibit smooth muscle contractions through activation of Na(+)-K(+)-ATPase.
Topics: Animals; Carbachol; Enzyme Activation; Female; Guinea Pigs; Histamine; Ileum; In Vitro Techniques; M | 1990 |
Interactions of palmitoyl carnitine with the endothelium in rat aorta.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1990 |
Mechanism of endothelin-induced contraction in guinea-pig trachea: comparison with rat aorta.
Topics: Animals; Aorta, Thoracic; Calcium; Carbachol; Endothelins; Guinea Pigs; In Vitro Techniques; Male; M | 1990 |
Substance P contracts the human iris sphincter: possible modulation by endogenous enkephalinase.
Topics: Aged; Aged, 80 and over; Carbachol; Female; Humans; Immunoenzyme Techniques; In Vitro Techniques; Ir | 1990 |
Characterization of beta-adrenoreceptors on smooth muscle cells from guinea pig stomach.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Binding, Competitive; Carbachol; Cyclic AMP; Epinephrine; Guin | 1990 |
Pre- and postjunctional muscarinic receptors in canine bronchi.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Animals; Bethanechol Compounds | 1990 |
Selective inhibition of responses to carbachol and McN-A-343 in the rabbit vas deferens.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Animals; Bis-Trimethylammonium | 1990 |
Leukotriene receptor antagonism and augmentation of beta-receptor-mediated events by LY171883.
Topics: 1-Methyl-3-isobutylxanthine; Acetophenones; Adrenergic beta-Agonists; Animals; Bronchodilator Agents | 1990 |
Tachykinin receptors in the circular muscle of the guinea-pig ileum.
Topics: Animals; Atropine; Carbachol; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscle Contraction; Mus | 1990 |
Gastrin-releasing peptide is a transmitter mediating porcine gallbladder contraction.
Topics: Animals; Atropine; Carbachol; Electric Stimulation; Gallbladder; Gastrin-Releasing Peptide; Gastroin | 1991 |
Effect of temperature reduction on responsiveness to cholinomimetics in the taenia caeci of the guinea-pig.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Animals; Atropine; Carbachol; | 1991 |
Effects of surgical sympathetic denervation on myo-inositol trisphosphate production and contraction in the dilator and sphincter smooth muscles of the rabbit iris: evidence for interaction between the cyclic AMP and calcium signaling systems.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Calcium; Carbachol; Cyclic AMP; Female; Inositol 1,4,5-Trispho | 1991 |
Mechanism of action of substance P in guinea-pig ileum longitudinal smooth muscle: a re-evaluation.
Topics: Animals; Bradykinin; Carbachol; Cell Membrane Permeability; Eledoisin; Guinea Pigs; Histamine; Ileum | 1990 |
Effect of tachykinins in small human airways.
Topics: Bronchi; Bronchoconstriction; Carbachol; Humans; In Vitro Techniques; Muscle Contraction; Muscle, Sm | 1991 |
Motility regulating effects of galanin on smooth muscle of porcine ileum.
Topics: Animals; Carbachol; Electric Stimulation; Female; Galanin; Ileum; Male; Muscle Contraction; Muscle, | 1991 |
Carbachol-induced nonspecific desensitization in guinea-pig ileum.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1991 |
Subtypes and excitation-contraction coupling mechanisms for neurokinin receptors in smooth muscle of the guinea-pig Taenia caeci.
Topics: Animals; Calcium; Carbachol; Guinea Pigs; In Vitro Techniques; Intestines; Ion Channels; Lithium; Mu | 1991 |
Evidence for protein kinase C modulation of the ciliary muscle response to carbachol and desensitization.
Topics: Alkaloids; Animals; Carbachol; Cattle; Ciliary Body; Diglycerides; Dinoprost; Enzyme Activation; Mus | 1991 |
The effect of chlorothiazide on neurally mediated contraction of rabbit bronchial smooth muscle.
Topics: Acetylcholinesterase; Animals; Atropine; Bronchi; Carbachol; Chlorothiazide; Cholinesterase Inhibito | 1992 |
Inositol 1,4,5-trisphosphate compartmentalization in tracheal smooth muscle.
Topics: Animals; Atropine; Carbachol; Chromatography, High Pressure Liquid; In Vitro Techniques; Inositol; I | 1992 |
Halothane- and enflurane-induced inhibition of phasic responses to carbachol in isolated guinea pig trachea.
Topics: Animals; Carbachol; Dose-Response Relationship, Drug; Enflurane; Guinea Pigs; Halothane; Kinetics; M | 1992 |
Effect of benzylamine and its metabolites on the responses of the isolated perfused mesenteric arterial bed of the rat.
Topics: Adenosine Triphosphate; Allylamine; Amine Oxidase (Copper-Containing); Ammonia; Animals; Benzylamine | 1991 |
Effect of ageing on response to nicotine in rabbit bronchial preparation.
Topics: Acetylcholine; Acetylcholinesterase; Aging; Animals; Atropine; Bronchi; Carbachol; Choline O-Acetylt | 1991 |
[Pharmacologic characteristics of human neurogenic bladder: response to KCl, carbachol, ATP and CaCl2].
Topics: Adenosine Triphosphate; Adolescent; Adult; Calcium Chloride; Carbachol; Child; Child, Preschool; Fem | 1991 |
[Effects of cooling on cholinergically-mediated contractions of tracheal muscle taken from immature and mature guinea pigs].
Topics: Acetylcholine; Acetylcholinesterase; Age Factors; Aging; Animals; Carbachol; Cholinergic Fibers; Dos | 1991 |
M3 cholinoceptors and P2y purinoceptors mediating relaxation of arteries in spontaneously hypertensive rats at prehypertensive stages.
Topics: Acetylcholine; Adenosine Triphosphate; Animals; Arteries; Carbachol; Cholinergic Antagonists; Endoth | 1991 |
Comparison of inhibitory effects of lithium and magnesium on longitudinal smooth muscle contraction.
Topics: Animals; Calcium; Carbachol; Digestive System; In Vitro Techniques; Lithium; Magnesium; Muscle Contr | 1991 |
The sources of calcium for carbachol-induced contraction in the circular smooth muscle of guinea-pig stomach.
Topics: Animals; Biopolymers; Caffeine; Calcium; Carbachol; Female; Guinea Pigs; In Vitro Techniques; Inosit | 1991 |
In vitro gallbladder motility in patients with radiolucent and radiopaque stones.
Topics: Adult; Aged; Carbachol; Cholelithiasis; Gallbladder; Humans; In Vitro Techniques; Male; Middle Aged; | 1991 |
Staurosporine inhibits the extent of acetylcholine receptor recovery from carbachol-induced desensitization in snake twitch fibres.
Topics: Alkaloids; Animals; Calcium; Carbachol; Cholinergic Antagonists; Electrophysiology; Ion Channel Gati | 1991 |
Comparison of the effect of calcium withdrawal from the medium and of blockade of extracellular calcium entry by isradipine on the contractile responses of the isolated rat stomach.
Topics: Animals; Calcium; Carbachol; Dihydropyridines; Female; Isradipine; Male; Muscle Contraction; Rats; R | 1991 |
Myopathic changes in indirectly stimulated mouse diaphragm after ecothiopate in vitro.
Topics: Animals; Carbachol; Diaphragm; Echothiophate Iodide; Electric Stimulation; In Vitro Techniques; Male | 1991 |
Neutrophil-derived oxidants modify CCK-OP-stimulated guinea pig gallbladder contraction in vitro.
Topics: Animals; Calcitonin Gene-Related Peptide; Carbachol; Chloramines; Gallbladder; Glutathione; Guinea P | 1991 |
Role of phosphatidic acid in carbachol-induced contraction in guinea pig Taenia coli.
Topics: Animals; Biological Transport, Active; Calcium; Carbachol; Colon; Diacylglycerol Kinase; Diglyceride | 1991 |
Mechanical properties of isolated smooth muscle from rabbit sphincter of Oddi and duodenum.
Topics: Animals; Carbachol; Dose-Response Relationship, Drug; Duodenum; In Vitro Techniques; Muscle Contract | 1991 |
Changes in bladder function in the one year spontaneously diabetic BB rat.
Topics: Adenosine Triphosphate; Animals; Blood Glucose; Body Weight; Carbachol; Diabetes Mellitus; Dose-Resp | 1991 |
Use of a modified Ussing chamber to monitor intestinal epithelial and smooth muscle functions.
Topics: Animals; Carbachol; Electrophysiology; Epithelium; In Vitro Techniques; Intestines; Male; Muscle Con | 1991 |
Hypertrophic smooth muscle in the partially obstructed opossum esophagus. Excitability and electrophysiological properties.
Topics: Animals; Carbachol; Electric Stimulation; Esophagus; Hypertrophy; Membrane Potentials; Muscle Contra | 1991 |
Effects of trimebutine on cytosolic Ca2+ and force transitions in intestinal smooth muscle.
Topics: Animals; Caffeine; Calcium; Carbachol; Cytosol; Fura-2; Guinea Pigs; In Vitro Techniques; Intestines | 1991 |
Propylbenzilycholine mustard (PrBCM)-sensitive cholinoceptors and contractile response to partial agonist in guinea pig ileal muscle.
Topics: Algorithms; Animals; Calcium; Carbachol; Dose-Response Relationship, Drug; Guinea Pigs; Ileum; In Vi | 1991 |
Blockade by the local anaesthetic, tetracaine, of desensitization of Ca-induced Ca release after muscarinic stimulation in smooth muscle.
Topics: Animals; Caffeine; Calcium; Carbachol; Dibucaine; Female; Guinea Pigs; Histamine; In Vitro Technique | 1991 |
Distribution and function of cholinergic receptors in the sheep detrusor muscle.
Topics: Acetylcholine; Acetylcholinesterase; Animals; Atropine; Carbachol; Cholinesterase Inhibitors; Gangli | 1991 |
Analogues of oxybutynin. Synthesis and antimuscarinic and bladder activity of some substituted 7-amino-1-hydroxy-5-heptyn-2-ones and related compounds.
Topics: Alkynes; Amines; Animals; Carbachol; Cyclobutanes; Female; Guinea Pigs; Mandelic Acids; Muscarinic A | 1991 |
Molecular modification of anticholinergics as probes for muscarinic receptors. Part 4. Ileal selective muscarinic antagonists.
Topics: Animals; Carbachol; Chromatography, Thin Layer; Electric Stimulation; Heart; Ileum; In Vitro Techniq | 1991 |
Role of cholinergic fibers in a center essential to animal hypnosis.
Topics: Animals; Atropine; Brain; Carbachol; Electric Stimulation; Hypnosis; Male; Microinjections; Models, | 1991 |
Measurements of intracellular calcium and contractility in human ciliary muscle.
Topics: Acetylcholine; Calcium; Carbachol; Cell Line; Humans; In Vitro Techniques; Intracellular Fluid; Memb | 1991 |
[Pharmacological analysis of drug interactions of disopyramide and its congeners with peripheral muscarinic acetylcholine receptors].
Topics: Animals; Binding, Competitive; Carbachol; Disopyramide; Drug Interactions; Female; Guinea Pigs; In V | 1991 |
[Effects of calcium ion on contractile response of guinea-pig gallbladder muscle strip to agonists].
Topics: Acetylcholine; Animals; Calcium; Calcium Channels; Carbachol; Ceruletide; Female; Gallbladder; Guine | 1990 |
Influence of the DA2-receptor agonist quinpirole on the guinea pig ileum.
Topics: Acetylcholine; Animals; Carbachol; Dopamine; Dopamine Agents; Drug Interactions; Electric Stimulatio | 1990 |
Effect of somatostatin on the canine gallbladder motility.
Topics: Acetylcholine; Animals; Atropine; Carbachol; Dogs; Electric Stimulation; Gallbladder; Guinea Pigs; M | 1990 |
Frusemide potentiates acetylcholine and carbachol in contracting the rat urinary bladder.
Topics: Acetylcholine; Animals; Carbachol; Drug Synergism; Female; Furosemide; Male; Muscle Contraction; Rat | 1990 |
Protein kinase C translocation in rat stomach fundus: effects of serotonin, carbamylcholine and phorbol dibutyrate.
Topics: Alkaloids; Animals; Carbachol; Gastric Fundus; Male; Muscle Contraction; Muscle, Smooth; Phorbol 12, | 1991 |
Calcium reversal, relaxation by calcium ion of various smooth muscles contracted by carbachol, norepinephrine or a phorbol ester in calcium-ion free medium.
Topics: Animals; Aorta, Thoracic; Calcium; Carbachol; Guinea Pigs; In Vitro Techniques; Male; Muscle Contrac | 1991 |
Effect of different bronchodilators on airway smooth muscle responsiveness to contractile agents.
Topics: Animals; Bronchodilator Agents; Carbachol; Dose-Response Relationship, Drug; Guinea Pigs; Histamine; | 1991 |
Effect of Desmodium adscendens fraction 3 on contractions of respiratory smooth muscle.
Topics: Animals; Antigens; Arachidonic Acid; Arachidonic Acids; Carbachol; Ethanol; Ghana; Guinea Pigs; Hist | 1990 |
Isolation of guinea pig gastric smooth muscle cells.
Topics: Animals; Calcium; Carbachol; Cell Separation; Guinea Pigs; Intracellular Membranes; Muscle Contracti | 1990 |
Mechanism of action of doxepin in the treatment of chronic urticaria.
Topics: Adult; Aged; Animals; Atropine; Carbachol; Chronic Disease; Dimaprit; Doxepin; Female; Gastric Juice | 1990 |
Effects of calcium, strontium, and barium salts on frog rectus abdominis.
Topics: Abdominal Muscles; Animals; Anura; Barium; Calcium; Carbachol; Muscle Contraction; Strontium | 1990 |
Effect of bradykinin on opossum esophageal longitudinal smooth muscle: evidence for novel bradykinin receptors.
Topics: Animals; Bradykinin; Carbachol; Esophagus; Female; Male; Muscle Contraction; Muscle, Smooth; Opossum | 1990 |
Atropine-resistant transmission in partially depolarized rat urinary bladder.
Topics: Animals; Atropine; Carbachol; Cholinesterase Inhibitors; Echothiophate Iodide; Electric Stimulation; | 1990 |
Actions of second messengers synthesized by various spasmogenic agents and their relation to mechanical responses in dog tracheal smooth muscle.
Topics: Animals; Benzofurans; Calcium; Carbachol; Cyclic AMP; Cyclic GMP; Dogs; Fura-2; Histamine; In Vitro | 1990 |
Agonist-induced contraction and accumulation of inositol phosphates in the guinea-pig detrusor: evidence that muscarinic and purinergic receptors raise intracellular calcium by different mechanisms.
Topics: Adenosine Triphosphate; Animals; Calcium; Calcium Channels; Carbachol; Electric Stimulation; Guinea | 1990 |
Relationship between sensitivity and density of muscarinic receptors in single smooth muscle cells of guinea pig taenia caecum prepared under three conditions.
Topics: Animals; Carbachol; Cecum; Guinea Pigs; In Vitro Techniques; Kinetics; Microbial Collagenase; Muscle | 1990 |
Effects of ouabain and EGTA on the inhibitory effect of Ca2+ on guinea pig stomach smooth muscle ('Ca reversal').
Topics: Animals; Calcium; Calcium Channel Blockers; Carbachol; Egtazic Acid; Female; Guinea Pigs; In Vitro T | 1990 |
Effect of sodium-transport inhibitors on airway smooth muscle contractility in vitro.
Topics: Amiloride; Animals; Bronchi; Carbachol; Cattle; Dose-Response Relationship, Drug; Histamine; Humans; | 1990 |
Okadaic acid uncouples myosin light chain phosphorylation and tension in smooth muscle.
Topics: Animals; Calcium; Carbachol; Cattle; Ethers, Cyclic; In Vitro Techniques; Muscle Contraction; Muscle | 1990 |
The effects of testosterone or insulin treatment on contractile responses of the rat vas deferens following castration or streptozotocin-induced diabetes mellitus.
Topics: Animals; Blood Glucose; Calcium; Carbachol; Diabetes Mellitus, Experimental; Electric Stimulation; I | 1990 |
Greater contraction is induced by pilocarpine than by carbachol at the same levels of cytosolic Ca2+ concentration in isolated longitudinal muscle of guinea pig ileum.
Topics: Animals; Calcium; Carbachol; Cytosol; Guinea Pigs; Ileum; In Vitro Techniques; Muscle Contraction; M | 1990 |
Desensitization and muscarinic re-sensitization of force and myosin light chain phosphorylation to cytoplasmic Ca2+ in smooth muscle.
Topics: Animals; Calcium; Calmodulin; Carbachol; Cytoplasm; Escin; Ethers, Cyclic; Guinea Pigs; Histamine; I | 1990 |
Regulation of guinea pig ileal electrolyte transport by M3-muscarinic acetylcholine receptors in vitro.
Topics: Animals; Biological Transport; Carbachol; Chlorides; Guinea Pigs; Heart Rate; Ileum; In Vitro Techni | 1990 |
Biliary and gut function following shock.
Topics: Animals; Carbachol; Electrophysiology; Gallbladder; Gastrointestinal Motility; Intestines; Muscle Co | 1990 |
Activation of propylbenzilylcholine mustard-sensitive muscarinic cholinoceptors more effectively utilizes cytosolic Ca2+ for contraction in guinea-pig intestinal smooth muscle.
Topics: Animals; Calcium; Carbachol; Cytosol; Fura-2; Guinea Pigs; In Vitro Techniques; Intestines; Male; Mu | 1990 |
Effects of extracellular acidosis on the action of smooth muscle relaxants.
Topics: Acidosis; Albuterol; Amiloride; Animals; Carbachol; Dogs; In Vitro Techniques; Isometric Contraction | 1990 |
Carbamylcholine- and 5-hydroxytryptamine-induced contraction in rat isolated airways: inhibition by calcitonin gene-related peptide.
Topics: Animals; Bronchi; Calcitonin Gene-Related Peptide; Carbachol; Humans; In Vitro Techniques; Indometha | 1990 |
PAF-induced bronchial hyperresponsiveness in the rabbit: contribution of platelets and airway smooth muscle.
Topics: Aerosols; Animals; Blood Platelets; Bronchi; Bronchoalveolar Lavage Fluid; Carbachol; Guinea Pigs; H | 1990 |
Sex steroid hormone receptors and human gallbladder motility in vitro.
Topics: Carbachol; Female; Gallbladder; Humans; In Vitro Techniques; Middle Aged; Muscle Contraction; Recept | 1990 |
Nerve-mediated functions in the circular and longitudinal muscle layers of the proximal female rabbit urethra.
Topics: Adrenergic Fibers; Animals; Autoradiography; Carbachol; Electric Stimulation; Female; In Vitro Techn | 1990 |
Synthesis of some 3-(1-azabicyclo[2.2.2]octyl) 3-amino-2-hydroxy-2-phenylpropionates: profile of antimuscarinic efficacy and selectivity.
Topics: Animals; Bridged Bicyclo Compounds; Bridged-Ring Compounds; Carbachol; Chemical Phenomena; Chemistry | 1990 |
Neural control of duodenal motor inhibition by antral contractions in dogs.
Topics: Animals; Carbachol; Dogs; Duodenum; Electric Stimulation; Muscle Contraction; Muscle, Smooth; Phento | 1990 |
Effects of cromakalim (BRL 34915) and pinacidil on normal and hypertrophied rat detrusor in vitro.
Topics: Animals; Benzopyrans; Carbachol; Cromakalim; Dose-Response Relationship, Drug; Electric Stimulation; | 1990 |
Lack of an effect of saxitonin on the contractility of isolated guinea-pig trachea, lung parenchyma and aorta.
Topics: Acetylcholine; Animals; Aorta; Carbachol; Endothelium; Endothelium, Vascular; Guinea Pigs; Histamine | 1990 |
Mechanical properties of isolated human esophageal smooth muscle.
Topics: Calcium; Carbachol; Esophagus; Humans; In Vitro Techniques; Isometric Contraction; Muscle Contractio | 1990 |
Effects of transmural field stimulation in isolated muscle strips from human esophagus.
Topics: Atropine; Carbachol; Electric Stimulation; Esophagus; Humans; In Vitro Techniques; Ketanserin; Muscl | 1990 |
Electrical and mechanical interactions between the muscle layers of canine proximal colon.
Topics: Animals; Carbachol; Colon; Dogs; Electric Conductivity; Electrophysiology; Evoked Potentials; Female | 1990 |
Contraction of smooth muscle of pig airway tissues from before birth to maturity.
Topics: Aging; Animals; Animals, Suckling; Bronchi; Carbachol; Fetus; Histamine; In Vitro Techniques; Muscle | 1990 |
Intracellular free magnesium concentration in the taenia isolated from guinea-pig caecum.
Topics: Animals; Carbachol; Guinea Pigs; Intestine, Large; Magnesium; Magnetic Resonance Spectroscopy; Muscl | 1990 |
Effects of variations in extracellular pH on spontaneous contractile activity and response to nerve stimulation in smooth muscle from rat urinary bladder.
Topics: Acid-Base Equilibrium; Animals; Carbachol; Electric Stimulation; Female; Hydrogen-Ion Concentration; | 1990 |
Dual effects of carbachol on cytosolic Ca2+ and contraction in intestinal smooth muscle.
Topics: Animals; Calcium; Carbachol; Cecum; Cytosol; Guinea Pigs; Ileum; In Vitro Techniques; Kinetics; Male | 1990 |
Metabolism and force in hypertrophic smooth muscle from rat urinary bladder.
Topics: Animals; Calcium; Carbachol; Electric Stimulation; Female; Hypertrophy; Isometric Contraction; Kinet | 1990 |
Muscarinic receptor reserve of airway smooth muscle and the response to isoproterenol.
Topics: Animals; Carbachol; Dogs; In Vitro Techniques; Isoproterenol; Muscle Contraction; Phenoxybenzamine; | 1990 |
Depletion of intracellular free Mg2+ in Mg2(+)- and Ca2(+)-free solution in the taenia isolated from guinea-pig caecum.
Topics: Adenosine Triphosphate; Animals; Calcium; Carbachol; Cecum; Female; Guinea Pigs; Hydrogen-Ion Concen | 1990 |
Mini-pig urinary bladder function: comparisons of in vitro anticholinergic responses and in vivo cystometry with drugs indicated for urinary incontinence.
Topics: Animals; Carbachol; Female; Guinea Pigs; Muscle Contraction; Parasympatholytics; Swine; Swine, Minia | 1990 |
Different effects of depolarization and muscarinic stimulation on the Ca2+/force relationship during the contraction-relaxation cycle in the guinea pig ileum.
Topics: Animals; Calcium; Carbachol; Guinea Pigs; Ileum; Muscle Contraction; Muscle Relaxation; Muscle, Smoo | 1990 |
Phorbol ester-induced release of endothelium-derived relaxing factor.
Topics: Animals; Aorta, Thoracic; Carbachol; Dose-Response Relationship, Drug; Endothelium, Vascular; Male; | 1990 |
The effects of temperature on contractile mechanisms of rainbow trout (Salmo gairdneri) intestine.
Topics: Animals; Calcium; Carbachol; Extracellular Space; Gastrointestinal Motility; Intestines; Muscle Cont | 1990 |
Inhibitory and excitatory responses to field stimulation in fetal and adult pig airway.
Topics: Animals; Bronchi; Carbachol; Electric Stimulation; Female; Fetus; In Vitro Techniques; Male; Muscle | 1990 |
Phosphatidic acid-induced contraction in guinea-pig taenia coli.
Topics: Animals; Calcium; Carbachol; Colon; Guinea Pigs; In Vitro Techniques; Muscle Contraction; Phosphatid | 1990 |
Altered carbachol-induced contractile responses of rat jejunal smooth muscle following local myenteric plexus ablation.
Topics: Animals; Benzalkonium Compounds; Carbachol; Jejunum; Male; Muscle Contraction; Muscle, Smooth; Myent | 1990 |
In vitro tracheal responses from mice chosen for in vivo lung cholinergic sensitivity.
Topics: Acetylcholine; Animals; Carbachol; In Vitro Techniques; Isoproterenol; Lung; Mice; Mice, Inbred A; M | 1990 |
Effects of papaverine on human isolated bladder muscle.
Topics: Calcium Channel Blockers; Carbachol; Female; Humans; In Vitro Techniques; Male; Middle Aged; Muscle | 1990 |
Changes in cytosolic CA2+ and contraction induced by various stimulants and relaxants in canine tracheal smooth muscle.
Topics: Animals; Benzofurans; Calcium; Carbachol; Colforsin; Cytosol; Dogs; Fura-2; Isoproterenol; Muscle Co | 1990 |
Structure-activity relationships of some Galbulimima alkaloids related to himbacine.
Topics: Alkaloids; Animals; Carbachol; Electric Stimulation; Furans; Guinea Pigs; Ileum; In Vitro Techniques | 1990 |
The acetylcholine receptor of the neuromuscular junction recognizes mecamylamine as a noncompetitive antagonist.
Topics: Amphibian Venoms; Animals; Bungarotoxins; Carbachol; Electric Conductivity; In Vitro Techniques; Ion | 1985 |
Effects of bronchoconstrictors and bronchodilators on a novel human small airway preparation.
Topics: Adenosine; Adenosine Triphosphate; Bronchi; Bronchodilator Agents; Carbachol; Histamine; Humans; In | 1985 |
Potentiation of nerve-induced bladder contractions after calcium channel blockade.
Topics: Animals; Calcium; Carbachol; Elasticity; Ion Channels; Male; Muscle Contraction; Muscle, Smooth; Pot | 1985 |
Contractile effects of vanadate on monkey and rabbit tracheal smooth muscle.
Topics: Animals; Calcium; Calcium Channel Blockers; Carbachol; Female; Histamine; In Vitro Techniques; Ion C | 1985 |
Regional selectivity of calcium blockers at intestinal level.
Topics: Animals; Calcium Channel Blockers; Carbachol; Colon; Duodenum; Edetic Acid; In Vitro Techniques; Ion | 1985 |
Alpha-adrenoceptors and muscarinic receptors in the isolated human prostate.
Topics: Acetylcholine; Aged; Carbachol; Clonidine; Electric Stimulation; Humans; Male; Middle Aged; Muscle C | 1985 |
Cooling-induced augmentation of the contractile response of the golden hamster tracheal muscle to substance P in-vitro.
Topics: Animals; Caffeine; Calcium; Carbachol; Cold Temperature; Cricetinae; In Vitro Techniques; Male; Meso | 1986 |
Pharmacological characterization of rat jejunal contractility after chronic ablation of the myenteric plexus.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Animals; Barium; Barium Compou | 1986 |
Effects of verapamil on the response of the guinea-pig tracheal muscle to carbachol.
Topics: Animals; Barium; Calcium; Carbachol; Female; Guinea Pigs; In Vitro Techniques; Ion Channels; Male; M | 1986 |
Calcium utilization by dispersed canine gastric smooth muscle cells.
Topics: Animals; Calcium; Carbachol; Dogs; Egtazic Acid; Female; Gastric Mucosa; Ion Channels; Male; Muscle | 1986 |
Effects of neurokinin A, substance P and electrical stimulation on the rabbit iris sphincter muscle.
Topics: Amino Acid Sequence; Animals; Capsaicin; Carbachol; Dose-Response Relationship, Drug; Electric Stimu | 1986 |
The calcium channel agonist BAY K8644 enhances the responsiveness of human airway muscle to KCl and histamine but not to carbachol.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1987 |
Effects of calcium, calcium channel blockers and Bay K 8644 on contractions induced by muscarinic receptor stimulation of isolated bladder muscle from rabbit and man.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1987 |
The role of substance P in the human urinary bladder.
Topics: Atropine; Capsaicin; Carbachol; Electric Stimulation; Female; Humans; In Vitro Techniques; Muscle Co | 1987 |
CI-922--a novel, potent antiallergic compound--I. Inhibition of mediator release in vitro.
Topics: Animals; Azoles; Carbachol; Guinea Pigs; Histamine Release; Humans; In Vitro Techniques; Indoles; Le | 1987 |
Pharmacological evidence for the possible coexistence of multiple receptor sites for mammalian tachykinins in rabbit iris sphincter smooth muscle.
Topics: Animals; Carbachol; Eledoisin; In Vitro Techniques; Iris; Muscle Contraction; Muscle, Smooth; Neurok | 1987 |
Non-competitive effects of disopyramide at the neuromuscular junction: evidence for endplate ion channel block.
Topics: Animals; Carbachol; Chickens; Disopyramide; Dose-Response Relationship, Drug; In Vitro Techniques; I | 1987 |
Comparison of the effects of clonidine and guanfacine on the histamine liberation from human mast cells and basophils and on the human bronchial smooth muscle activity.
Topics: Adrenergic alpha-Agonists; Basophils; Bronchi; Carbachol; Cimetidine; Clonidine; Electric Stimulatio | 1987 |
Differential effect of ketamine on cholinergic- and noncholinergic-induced contractions of isolated guinea-pig bronchi.
Topics: Animals; Bronchi; Carbachol; Electric Stimulation; Guinea Pigs; In Vitro Techniques; Ketamine; Muscl | 1987 |
Muscarinic receptors on nerves and muscles in opossum esophagus muscularis mucosa.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Animals; Atropine; Carbachol; | 1987 |
Calcium and contractions of isolated smooth muscle cells from rat myometrium.
Topics: Animals; Buffers; Calcium; Carbachol; Egtazic Acid; Female; In Vitro Techniques; Muscle Contraction; | 1987 |
The prostaglandin response in guinea-pig taenia caeci and trachea smooth muscle of different ages.
Topics: Aging; Animals; Carbachol; Cecum; Dinoprost; Dinoprostone; Guinea Pigs; In Vitro Techniques; Ion Cha | 1988 |
Development of non-cholinergic, non-adrenergic excitatory and inhibitory responses to intramural nerve stimulation in rat stomach.
Topics: Animals; Atropine; Carbachol; Electric Stimulation; Gastrointestinal Motility; Muscle Contraction; M | 1988 |
Characterization of receptors for calcitonin gene-related peptide on gastric smooth muscle cells.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Calcitonin; Calcitonin Gene-Related Peptide; Carbachol; Cells, | 1988 |
Is airway hyperresponsiveness a smooth muscle abnormality?
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1988 |
Endothelin and Ca++ agonist Bay K 8644: different vasoconstrictive properties.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1988 |
Mode of action of calcium antagonists on responses to spasmogens and antigen challenge in human airway smooth muscle.
Topics: Allergens; Antigens, Plant; Bronchi; Calcium Channel Blockers; Carbachol; Culture Techniques; Dose-R | 1988 |
Species differences in the effects of prostaglandins on inositol trisphosphate accumulation, phosphatidic acid formation, myosin light chain phosphorylation and contraction in iris sphincter of the mammalian eye: interaction with the cyclic AMP system.
Topics: Animals; Atropine; Calcium; Carbachol; Cats; Cattle; Cyclic AMP; Dose-Response Relationship, Drug; I | 1988 |
ANP relaxes bovine tracheal smooth muscle and increases cGMP.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Atrial Natriuretic Factor; Carbachol; Cattle; Cyclic AMP; Cycl | 1989 |
Assessment of selectivity of muscarinic antagonists for M1 and M2 receptors in rabbit isolated vas deferens.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Animals; Atrial Function; Carb | 1988 |
Differential effects of prostaglandin E2 on contractions of airway smooth muscle.
Topics: 1-Methyl-3-isobutylxanthine; Acetylcholine; Animals; Atropine; Carbachol; Dimethylphenylpiperazinium | 1989 |
Influence of electrical field stimulation on antigen-induced contraction and mediator release in the guinea pig isolated superfused trachea and bronchus.
Topics: Animals; Antigens; Bronchi; Carbachol; Catecholamines; Electric Stimulation; Guinea Pigs; Histamine | 1989 |
Classification of tachykinin receptors in muscularis mucosae of opossum oesophagus.
Topics: Animals; Carbachol; Electric Stimulation; Eledoisin; Esophagus; In Vitro Techniques; Mucous Membrane | 1989 |
Sensitization alters contractile responses and calcium influx in human airway smooth muscle.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1989 |
Contractile properties of human prostate adenomas and the development of infravesical obstruction.
Topics: Aged; Brimonidine Tartrate; Carbachol; Humans; Male; Muscle Contraction; Muscle, Smooth; Phenylephri | 1989 |
Regional differences in the motor and inflammatory responses to capsaicin in guinea pig airways. Correlation with content and release of substance P-like immunoreactivity.
Topics: Animals; Biomarkers; Blood Proteins; Bronchi; Calcitonin Gene-Related Peptide; Capsaicin; Carbachol; | 1989 |
Multiple sources of calcium for contraction of the human urinary bladder muscle.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1989 |
Receptor-coupled, permeabilized smooth muscle. Role of the phosphatidylinositol cascade, G-proteins, and modulation of the contractile response to Ca2+.
Topics: Animals; Bacterial Toxins; Calcium; Carbachol; Cell Membrane Permeability; GTP-Binding Proteins; Gua | 1989 |
Loading of fura-2/AM with an aid of DFP on single smooth muscle cells prepared from guinea pig taenia coli.
Topics: Animals; Benzofurans; Biological Transport; Caffeine; Calcium; Carbachol; Cholinesterases; Colon; Eg | 1989 |
Effect of purified Clostridium difficile toxins on intestinal smooth muscle. I. Toxin A.
Topics: Action Potentials; Animals; Bacterial Toxins; Carbachol; Clostridium; Enterotoxins; Female; Ileum; I | 1989 |
Effect of purified Clostridium difficile toxins on intestinal smooth muscle. II. Toxin B.
Topics: Action Potentials; Animals; Bacterial Toxins; Carbachol; Clostridium; Enterotoxins; Ileum; Intestine | 1989 |
Comparison of relaxation induced by glyceryl trinitrate, isosorbide dinitrate, and sodium nitroprusside in bovine airways.
Topics: Animals; Carbachol; Cattle; Dose-Response Relationship, Drug; Ferricyanides; In Vitro Techniques; Is | 1989 |
Cytosolic heparin inhibits muscarinic and alpha-adrenergic Ca2+ release in smooth muscle. Physiological role of inositol 1,4,5-trisphosphate in pharmacomechanical coupling.
Topics: Animals; Caffeine; Carbachol; Cytosol; Egtazic Acid; Guinea Pigs; Heparin; Ileum; In Vitro Technique | 1989 |
Effects of pluronic F-127 on loading of fura 2/AM into single smooth muscle cells isolated from guinea pig taenia coli.
Topics: Animals; Benzofurans; Carbachol; Colon; Egtazic Acid; Fluorescent Dyes; Fura-2; Guinea Pigs; In Vitr | 1989 |
Effects of neonatal capsaicin treatment and streptozotocin-induced diabetes on urinary bladder function in rats.
Topics: Animals; Animals, Newborn; Capsaicin; Carbachol; Diabetes Mellitus, Experimental; Electric Stimulati | 1989 |
Contractile responses in bladder body, bladder neck and prostate from rat, guinea pig and cat.
Topics: Animals; Carbachol; Cats; Dose-Response Relationship, Drug; Female; Guinea Pigs; Histamine; In Vitro | 1989 |
Contractile force and intracellular Ca2+ during relaxation of canine tracheal smooth muscle.
Topics: Acetylcholine; Aequorin; Animals; Calcium; Carbachol; Colforsin; Dogs; In Vitro Techniques; Indicato | 1989 |
Modulation of spontaneous motility by GABAA receptor antagonism in the guinea pig isolated ileum.
Topics: 3-Mercaptopropionic Acid; Acetylcholine; Androstanes; Animals; Azasteroids; Bicuculline; Carbachol; | 1989 |
Comparison of contractions to serotonin, carbamylcholine and prostaglandin F2 alpha in rat stomach fundus.
Topics: Animals; Carbachol; Diltiazem; Dinoprost; Gastric Fundus; Guanidines; In Vitro Techniques; Isoproter | 1989 |
The pharmacological properties of the peptide, endothelin.
Topics: Animals; Blood Pressure; Calcium Channels; Carbachol; Cerebral Cortex; Endothelins; Female; Guinea P | 1989 |
AlF-4 inhibits the accumulation of Ca in the endoplasmic reticulum in intact myometrial strips, but not in the rabbit ear artery.
Topics: Aluminum; Aluminum Chloride; Aluminum Compounds; Animals; Arteries; Calcium; Calcium Channels; Carba | 1989 |
Altered smooth muscle contraction and sodium pump activity in the inflamed rat intestine.
Topics: Animals; Carbachol; In Vitro Techniques; Inflammation; Jejunum; Kinetics; Male; Microsomes; Muscle C | 1989 |
Inhibitory action of atrial natriuretic factor on cholinergic and nonadrenergic, noncholinergic neurotransmission in guinea pig small intestine.
Topics: Animals; Atrial Natriuretic Factor; Carbachol; Electric Stimulation; Guinea Pigs; Histamine; Ileum; | 1989 |
The different contributions of prostaglandins (E1, E2, F2 alpha, D2) to the tone and neurogenic response of bovine iris sphincter muscle.
Topics: Animals; Carbachol; Cattle; Electric Stimulation; In Vitro Techniques; Indomethacin; Iris; Muscle Co | 1989 |
[Effect of various muscle constrictors and cyclic AMP related relaxants on tension and intracellular concentration of Ca of tracheal smooth muscle].
Topics: Animals; Calcium; Carbachol; Cyclic AMP; Dogs; In Vitro Techniques; Muscle Contraction; Muscle, Smoo | 1989 |
Calcitonin gene-related peptide action on intestinal circular muscle.
Topics: Animals; Apamin; Atropine; Calcitonin; Calcitonin Gene-Related Peptide; Carbachol; Female; Gastroint | 1989 |
Responses of the isolated rectum of the rainbow lizard (Agama agama) to sympathomimetics.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Carbachol; Epinephrine; Isoprote | 1989 |
Characterization of autonomic receptors in neonatal urinary tract smooth muscle.
Topics: Adrenergic Agonists; Animals; Animals, Newborn; Carbachol; Clonidine; Dihydroalprenolol; Dose-Respon | 1989 |
Comparative effects of verapamil and D-600 on the contractile responses produced by neurotransmitters and depolarizing agents in the rat isolated seminal vesicle.
Topics: Acetylcholine; Animals; Carbachol; Clonidine; Gallopamil; In Vitro Techniques; Male; Muscle Contract | 1989 |
Dual effects of dynorphin-(1-13) on cholinergic and substance P-ergic transmissions in the rabbit iris sphincter muscle.
Topics: Acetylcholine; Animals; Carbachol; Dynorphins; Electric Stimulation; Endorphins; Female; In Vitro Te | 1985 |
Effects of verapamil on the contractions of guinea-pig tracheal muscle induced by Ca, Sr and Ba.
Topics: Animals; Barium; Calcium; Carbachol; Dinoprost; Guinea Pigs; In Vitro Techniques; Indomethacin; Ion | 1985 |
Some characterization of the responses to substance P and other tachykinins in rabbit iris sphincter muscle.
Topics: Animals; Atropine; Carbachol; Eledoisin; In Vitro Techniques; Iris; Kinins; Muscle Contraction; Musc | 1985 |
Protein kinase C regulates the tonic but not the phasic component of contraction in guinea-pig ileum.
Topics: Animals; Carbachol; Down-Regulation; Female; Guinea Pigs; Ileum; In Vitro Techniques; Inositol Phosp | 1989 |
Rapid myosin phosphorylation transients in phasic contractions in chicken gizzard smooth muscle.
Topics: Animals; Atropine; Carbachol; Chickens; Electric Stimulation; Gizzard, Avian; Muscle Contraction; Mu | 1989 |
Phosphorylation of smooth muscle myosin heavy and light chains. Effects of phorbol dibutyrate and agonists.
Topics: Animals; Carbachol; Cattle; Cells, Cultured; Electrophoresis, Gel, Two-Dimensional; In Vitro Techniq | 1989 |
Lowering Po2 induces epithelium-dependent relaxation in isolated canine bronchi.
Topics: Animals; Bronchi; Carbachol; Dogs; Epithelium; Female; In Vitro Techniques; Male; Muscle Contraction | 1989 |
Phorbol ester effects on coupling mechanisms during cholinergic contraction of swine tracheal smooth muscle.
Topics: Amiloride; Animals; Carbachol; In Vitro Techniques; Inositol Phosphates; Membrane Potentials; Muscle | 1989 |
Pharmacological activity of N-methyl-carbamylcholine, a novel acetylcholine receptor agonist with selectivity for nicotinic receptors.
Topics: Adrenal Medulla; Animals; Behavior, Animal; Blood Pressure; Carbachol; Cattle; Ganglia, Sympathetic; | 1989 |
Stimulus-dependent pacemaker activity in the distal canine lower esophageal sphincter.
Topics: Animals; Barium; Barium Compounds; Carbachol; Chlorides; Dogs; Electric Stimulation; Esophagogastric | 1989 |
Second messenger effects on the myosin phosphorylation system in smooth muscle.
Topics: Calcium; Carbachol; Cells, Cultured; Cytoplasm; Humans; Muscle Contraction; Muscle, Smooth; Myosin-L | 1989 |
[Arg8]vasopressin-induced contractions of rabbit urinary bladder smooth muscle.
Topics: Animals; Arginine Vasopressin; Calcium; Carbachol; In Vitro Techniques; Indomethacin; Male; Muscle C | 1989 |
Effects of endothelin on the mechanical activity and cytosolic calcium level of various types of smooth muscle.
Topics: Animals; Aorta, Thoracic; Calcium; Carbachol; Cecum; Cytosol; Endothelins; Female; Ileum; In Vitro T | 1989 |
[Role of K-channel and suppression of caecal smooth-muscle contraction in the guinea-pig during carbachol induced short-term desensitization].
Topics: Animals; Carbachol; Cecum; Depression, Chemical; Guinea Pigs; In Vitro Techniques; Muscle Contractio | 1989 |
Effects of castration and diabetes mellitus on cholinergic responsiveness and muscarinic receptors in the rat vas deferens.
Topics: Animals; Atropine; Binding Sites; Carbachol; Diabetes Mellitus, Experimental; Male; Muscle Contracti | 1989 |
Vasoactive intestinal polypeptide and non-adrenergic, non-cholinergic inhibition in lower oesophageal sphincter of opossum.
Topics: Animals; Autonomic Nervous System; Carbachol; Electric Stimulation; Electrophysiology; Esophagogastr | 1989 |
Pharmacological characterization of neural mechanisms regulating mucosal ion transport in mouse jejunum.
Topics: Action Potentials; Animals; Atropine; Biological Transport; Carbachol; Dimethylphenylpiperazinium Io | 1989 |
Perfused bronchial segment and bronchial strip: narrowing vs. isometric force by mediators.
Topics: Airway Resistance; Animals; Bronchi; Carbachol; Histamine; In Vitro Techniques; Muscle Contraction; | 1989 |
Neuromuscular effects of three phospholipases A2 from the venom of the Australian king brown snake Pseudechis australis.
Topics: Acetylcholine; Animals; Carbachol; Chickens; Elapid Venoms; In Vitro Techniques; Mice; Muscle Contra | 1989 |
Inhibitory effect of lithium on muscle contractions caused by various stimulants in guinea-pig ileum.
Topics: Animals; Carbachol; Cytosol; Guinea Pigs; Ileum; In Vitro Techniques; Lithium; Male; Muscle Contract | 1989 |
Characterization of contractile prostanoid receptors on human airway smooth muscle.
Topics: Atropine; Biphenyl Compounds; Bronchi; Carbachol; Dinoprost; Dinoprostone; Heptanoic Acids; Humans; | 1989 |
Pacemaker activity in the proximal lower oesophageal sphincter of the dog.
Topics: Action Potentials; Animals; Atropine; Biological Clocks; Carbachol; Dogs; Esophagogastric Junction; | 1989 |
Cholinergic receptors in the extraocular rectus muscle of the rabbit.
Topics: Acetylcholine; Animals; Carbachol; Dimethylphenylpiperazinium Iodide; Female; Hexamethonium Compound | 1989 |
Metabolic cost of processes linking excitation to contraction in smooth muscle.
Topics: Animals; Carbachol; Energy Metabolism; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth | 1989 |
[Effects of prostaglandins, leukotrienes, VIP, carbachol and isopropylnoradrenaline on uterine and vaginal motility in the chicken].
Topics: Animals; Carbachol; Chickens; Electromyography; Female; Isoproterenol; Leukotrienes; Muscle Contract | 1989 |
Oestrogen-induced changes in muscarinic receptor density and contractile responses in the female rabbit urinary bladder.
Topics: Animals; Carbachol; Electric Stimulation; Estrogens; Female; Membrane Potentials; Muscle Contraction | 1989 |
Effect of ACh on electrical and mechanical activity in guinea pig coronary arteries.
Topics: Acetylcholine; Animals; Bradykinin; Carbachol; Coronary Vessels; Electrophysiology; Endothelium, Vas | 1989 |
Divergent pharmacological effects of three calmodulin antagonists, N-(6-aminohexyl)-5-chloro-1-naphthalenesulfonamide (W-7), chlorpromazine and calmidazolium, on isometric tension development and myosin light chain phosphorylation in intact bovine trachea
Topics: Animals; Atropine; Calmodulin; Carbachol; Cattle; Chlorpromazine; Imidazoles; In Vitro Techniques; M | 1989 |
Effects of alpha,beta-methylene ATP on potentiation of contractions to field stimulation of rat vas deferens by carbachol.
Topics: Adenosine Triphosphate; Animals; Carbachol; Drug Synergism; Electric Stimulation; Epididymis; In Vit | 1989 |
Characterization of histamine receptors in tracheal smooth muscle of Mastomys natalensis.
Topics: Animals; Carbachol; Female; In Vitro Techniques; Male; Methylhistamines; Muridae; Muscle Contraction | 1989 |
The interaction of hexamethonium with muscarinic receptor subtypes in vitro.
Topics: Animals; Carbachol; Diamines; Guinea Pigs; Hexamethonium Compounds; In Vitro Techniques; Kinetics; M | 1989 |
Co-regulation of tracheal tone by cyclic AMP- and cyclic GMP-dependent mechanisms.
Topics: Animals; Bucladesine; Carbachol; Colforsin; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug | 1987 |
Inhibitory effects of opioids in a circular muscle-myenteric plexus preparation of guinea-pig ileum.
Topics: Animals; Carbachol; Electric Stimulation; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Female; | 1987 |
Does the hydrolysis of inositol phospholipids lead to the opening of voltage operated Ca2+ channels in guinea-pig ileum? Studies with fluoride ions and caffeine.
Topics: Animals; Caffeine; Calcium; Carbachol; Colforsin; Cyclic AMP; Fluorides; Guinea Pigs; Ileum; Isoprot | 1988 |
Indications for P2-purinoceptor subtypes in guinea pig smooth muscle.
Topics: 4-Chloromercuribenzenesulfonate; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Atropine; C | 1988 |
An analysis of the functional interactions of selected contractile agonists in the guinea pig isolated trachea.
Topics: Algorithms; Animals; Carbachol; Dose-Response Relationship, Drug; Guinea Pigs; Histamine; Leukotrien | 1988 |
The response of autonomic receptors to castration and testosterone in the urinary bladder of the rabbit.
Topics: Animals; Carbachol; Castration; Male; Muscle Contraction; Muscle, Smooth; Phenylephrine; Rabbits; Re | 1988 |
Muscarinic M1- and M2-receptors mediating opposite effects on neuromuscular transmission in rabbit vas deferens.
Topics: Animals; Carbachol; Electric Stimulation; In Vitro Techniques; Male; Muscle Contraction; Neuromuscul | 1988 |
Short-term desensitization of guinea-pig taenia caecum induced by carbachol occurs at intracellular Ca stores and that by histamine at H1-receptors.
Topics: Animals; Caffeine; Calcium; Calcium Channels; Carbachol; Cecum; Female; Guinea Pigs; Histamine; In V | 1988 |
U19052 (ICIAm): a novel leukotriene analog which antagonizes LTC4, LTD4, and LTE4.
Topics: Animals; Carbachol; Fatty Acids, Unsaturated; Guinea Pigs; Histamine; Ileum; In Vitro Techniques; Le | 1988 |
Effect of paf-acether on isoprenaline-induced relaxation in isolated tracheal segments of rats and guinea pigs.
Topics: Animals; Carbachol; Guinea Pigs; In Vitro Techniques; Isoproterenol; Male; Muscle Contraction; Muscl | 1988 |
Different effects of neuropeptide Y on electrically induced contractions in the longitudinal and circular smooth muscle layers of the female rabbit urethra.
Topics: Animals; Carbachol; Electric Stimulation; Female; Muscle Contraction; Muscle, Smooth; Neuropeptide Y | 1988 |
Effect of verapamil and diltiazem on isolated gastro-oesophageal sphincter of the rat.
Topics: Animals; Benzazepines; Carbachol; Diltiazem; Esophagogastric Junction; Female; In Vitro Techniques; | 1985 |
Muscarinic receptor agonist-antagonist interaction in the rat rectum: are there ways of activating the same receptors?
Topics: Acetylcholine; Animals; Atropine; Carbachol; Drug Interactions; Female; Gallamine Triethiodide; Male | 1985 |
Pharmacological actions of ifenprodil in the rat isolated anococcygeus muscle.
Topics: Adrenergic alpha-Antagonists; Animals; Calcium Chloride; Carbachol; In Vitro Techniques; Male; Metho | 1985 |
Effects of metoclopramide and domperidone on cholinergically mediated contractions of human isolated stomach muscle.
Topics: Acetylcholine; Atropine; Carbachol; Domperidone; Electric Stimulation; Humans; In Vitro Techniques; | 1985 |
Magnesium ions and oxytocin sensitivity of the male mouse anococcygeus.
Topics: Animals; Arginine Vasopressin; Carbachol; In Vitro Techniques; Lypressin; Magnesium; Male; Methoxami | 1985 |
A comparison of the action of the endothelium-derived relaxant factor and the inhibitory factor from the bovine retractor penis on rabbit aortic smooth muscle.
Topics: Animals; Carbachol; Catechols; Cattle; Endothelium; Flurbiprofen; Guanylate Cyclase; In Vitro Techni | 1986 |
The effect of varying carbachol concentration on the slope of Schild plots of selective beta-adrenoceptor antagonists in the carbachol-contracted guinea-pig trachea.
Topics: Adrenergic beta-Antagonists; Albuterol; Animals; Atenolol; Carbachol; Guinea Pigs; In Vitro Techniqu | 1986 |
Partial agonism and functional selectivity: a study on beta-adrenoceptor mediated effects in tracheal, cardiac and skeletal muscle.
Topics: Adrenergic beta-Agonists; Animals; Benzyl Alcohols; Bronchodilator Agents; Carbachol; Ethanolamines; | 1986 |
Lithium dampens neurotransmitter response in smooth muscle: relevance to action in affective illness.
Topics: Animals; Atropine; Carbachol; Guinea Pigs; Histamine; In Vitro Techniques; Lithium; Male; Muscle Con | 1986 |
Chemically stable homocinnamyl analogues of the leukotrienes: synthesis and preliminary biological evaluation.
Topics: Aminopeptidases; Animals; Carbachol; Cinnamates; gamma-Glutamyltransferase; Guinea Pigs; Indicators | 1986 |
Evidence against VIP-involvement in neurogenic relaxations of the mouse anococcygeus muscle.
Topics: Animals; Carbachol; Chymotrypsin; Electric Stimulation; Immune Sera; In Vitro Techniques; Male; Mice | 1986 |
Influence of calcium lack and nifedipine on carbachol-, potassium- and quinine-induced contractions of the lizard isolated rectum.
Topics: Animals; Calcium; Carbachol; Kinetics; Lizards; Male; Muscle Contraction; Muscle, Smooth; Nifedipine | 1986 |
Carbachol contracture of stomach smooth muscle of the newt in calcium-free solution.
Topics: Animals; Calcium; Carbachol; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; Potassium; Sal | 1987 |
Calcium loading properties of carbachol-sensitive calcium store in calcium-depleted stomach smooth muscle of the newt.
Topics: Animals; Calcium; Carbachol; Gastric Mucosa; In Vitro Techniques; Muscle Contraction; Muscle, Smooth | 1987 |
An investigation of the mechanism involved in the cholinergic action of meptazinol.
Topics: Animals; Atropine; Azepines; Benzenaminium, 4,4'-(3-oxo-1,5-pentanediyl)bis(N,N-dimethyl-N-2-propeny | 1987 |
Gastric antisecretory and antiulcer effects of WHR1582A, a compound exerting alpha-2 adrenoceptor agonist activity.
Topics: Adrenergic alpha-Agonists; Animals; Anti-Ulcer Agents; Aspirin; Carbachol; Clonidine; Cysteamine; Di | 1987 |
AF-DX 116, a cardioselective muscarinic antagonist.
Topics: Animals; Atropine; Bethanechol; Bethanechol Compounds; Carbachol; Cats; Dimethylphenylpiperazinium I | 1987 |
Effects of spasmogens on relaxant dose-response curves to full or partial agonists at beta-adrenoceptors of guinea pig isolated trachea.
Topics: Adrenergic beta-Agonists; Animals; Carbachol; Dose-Response Relationship, Drug; Drug Interactions; G | 1987 |
Excitatory innervation of the rabbit rectococcygeus muscle by enteric nerves from the terminal large intestine.
Topics: Animals; Atropine; Carbachol; Colon; Electrophysiology; Ganglionic Blockers; Intestine, Large; Muscl | 1987 |
(R)-nipecotic acid ethyl ester: a direct-acting cholinergic agonist that displays greater efficacy at M2 than at M1 muscarinic receptors.
Topics: Adenylyl Cyclase Inhibitors; Animals; Bethanechol; Bethanechol Compounds; Binding, Competitive; Carb | 1987 |
Prolonged supersensitivity to noradrenaline of smooth muscle of the epididymal half of the rat vas deferens denervated by vasectomy.
Topics: Adrenergic alpha-Agonists; Animals; Carbachol; Denervation; Epididymis; In Vitro Techniques; Male; M | 1987 |
(+/-)-Pindolol has beta 2-adrenoceptor antagonist but not agonist action on the costo-uterine muscle of the rat.
Topics: Adrenergic beta-Antagonists; Animals; Carbachol; Electric Stimulation; Female; In Vitro Techniques; | 1987 |
Effects of nicorandil on isolated smooth muscle cells from guinea-pig taenia caeci.
Topics: Animals; Biological Transport, Active; Calcium; Carbachol; Cecum; Guinea Pigs; In Vitro Techniques; | 1988 |
The site of action of trimethaphan-induced neuromuscular blockade in isolated rat and frog muscle.
Topics: Animals; Bungarotoxins; Caffeine; Carbachol; Electric Stimulation; Hexamethonium; Hexamethonium Comp | 1988 |
Effects of dietary poly-unsaturated fatty acids on tracheal histaminergic and cholinergic responsiveness in experimental models of bronchial hypersensitivity and hyperreactivity.
Topics: alpha-Linolenic Acid; Animals; Bronchial Diseases; Carbachol; Dietary Fats; Fatty Acids, Unsaturated | 1987 |
Palytoxin-induced K+ efflux from ileal longitudinal smooth muscle of the guinea-pig.
Topics: Acrylamides; Animals; Atropine; Calcium; Carbachol; Cardiac Glycosides; Cnidarian Venoms; Guinea Pig | 1988 |
[Action of trimethyl 3,3-N-hexene-5-lactam on the mechanical properties of the longitudinal fibers of the rat colon. An in vitro study].
Topics: Animals; Atropine; Carbachol; Colon; Electric Stimulation; Hexamethonium; Hexamethonium Compounds; I | 1987 |
Tonic and rhythmic contractions induced by dopamine and related amines in rat vasa deferentia are pharmacologically separable.
Topics: Amines; Animals; Calcium; Carbachol; Cocaine; Dopamine; In Vitro Techniques; Male; Methoxamine; Musc | 1988 |
Evidence for adenosine triphosphate as an excitatory transmitter in guinea-pig, rabbit and pig urinary bladder.
Topics: Acetylcholine; Action Potentials; Adenosine Triphosphate; Animals; Atropine; Carbachol; Dose-Respons | 1988 |
Problems associated with the application of the Cheng-Prusoff relationship to estimate atropine affinity constants using functional tissue responses.
Topics: Animals; Atropine; Carbachol; Enzyme Inhibitors; Guinea Pigs; Kinetics; Male; Mathematics; Methods; | 1989 |
Different mechanisms of contraction generation in circular muscle of canine colon.
Topics: Animals; Calcium; Carbachol; Colon; Dogs; Evoked Potentials; Female; Gallopamil; In Vitro Techniques | 1989 |
Cholinergic responsiveness of intestinal muscle in the pregnant guinea pig.
Topics: Animals; Carbachol; Dose-Response Relationship, Drug; Female; Guinea Pigs; Intestines; Muscle Contra | 1989 |
Effect of three weeks' treatment with budesonide on in vitro contractile and relaxant airway effects in the rat.
Topics: Animals; Body Weight; Budesonide; Carbachol; Culture Techniques; Glucocorticoids; Male; Muscle Contr | 1989 |
Stereoselectivity of muscarinic receptors in vivo and in vitro for oxotremorine analogues. N-[4-(tertiary amino)-2-butynyl]-5-methyl-2-pyrrolidones.
Topics: Abdominal Muscles; Animals; Atropine; Carbachol; Chemical Phenomena; Chemistry; Guinea Pigs; Ileum; | 1985 |
Phosphorylation of type II regulatory subunit of cAMP-dependent protein kinase in intact smooth muscle.
Topics: Adenosine Triphosphate; Animals; Carbachol; Cattle; Cyclic AMP; Isoproterenol; Kinetics; Muscle Cont | 1985 |
Hypothermia-induced supersensitivity to adenosine for responses mediated via A1-receptors but not A2-receptors.
Topics: 2-Chloroadenosine; Adenosine; Animals; Carbachol; Female; Guinea Pigs; Heart; Hypothermia; Ileum; In | 1985 |
L-AMP-PCP, an ATP receptor agonist in guinea-pig bladder, is inactive on taenia coli.
Topics: 5'-Nucleotidase; Adenosine Triphosphate; Animals; Carbachol; Colon; Guinea Pigs; In Vitro Techniques | 1985 |
Steric aspects of agonism and antagonism at beta-adrenoceptors: experiments with the enantiomers of clenbuterol.
Topics: Animals; Carbachol; Clenbuterol; Ethanolamines; Guinea Pigs; Heart Ventricles; In Vitro Techniques; | 1985 |
Effects of cholinergic drugs and 4-aminopyridine on cat ciliary muscle contractility.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Atropine; Carbachol; Cats; Ciliary Body; Muscle Contractio | 1985 |
Synthesis and biological activity of a linear fragment of the atrial natriuretic factor (ANF).
Topics: Adrenal Cortex; Aldosterone; Animals; Aorta, Thoracic; Atrial Natriuretic Factor; Binding, Competiti | 1985 |
Some pharmacological actions of nisoxetine, a bicyclic inhibitor of noradrenaline uptake.
Topics: Animals; Bradykinin; Carbachol; Desipramine; Fluoxetine; Guinea Pigs; Histamine; In Vitro Techniques | 1985 |
Potentiation by cholinoceptor agonists of contractions to field stimulation of rat vas deferens.
Topics: Animals; Atropine; Calcium; Carbachol; Electric Stimulation; In Vitro Techniques; Male; Muscle Contr | 1985 |
A comparative study of electrical field stimulation of the guinea-pig, ferret and marmoset urinary bladder.
Topics: Adenosine Triphosphate; Animals; Atropine; Callitrichinae; Carbachol; Electric Stimulation; Female; | 1985 |
Structure-activity relationships among benextramine-related tetraamine disulfides at peripheral alpha-adrenoreceptors.
Topics: Animals; Atrial Function; Biological Assay; Carbachol; Chemical Phenomena; Chemistry; Cystamine; Dis | 1985 |
The influence of Bordetella pertussis and its constituents on the beta-adrenergic receptor in the guinea pig respiratory system.
Topics: Animals; Carbachol; Endotoxins; Epinephrine; Guinea Pigs; Isoproterenol; Lung; Male; Muscle Contract | 1986 |
Influence of the epithelium on responsiveness of guinea-pig isolated trachea to contractile and relaxant agonists.
Topics: Acetylcholine; Animals; Asthma; Autoradiography; Carbachol; Cimetidine; Colforsin; Dose-Response Rel | 1986 |
Receptor-responses in fresh human ciliary muscle.
Topics: Angiotensin II; Atropine; Carbachol; Ciliary Body; Humans; In Vitro Techniques; Isoproterenol; Muscl | 1986 |
Oxygen-dependent tension in vascular smooth muscle. Does the endothelium play a role?
Topics: Animals; Carbachol; Cyclic GMP; Dogs; Ductus Arteriosus; Endothelium; Female; Hypoxia; Muscle Contra | 1986 |
Phosphatidylinositol response to cholinergic agonists in airway smooth muscle: relationship to contraction and muscarinic receptor occupancy.
Topics: Acetylcholine; Animals; Atropine; Benzodiazepinones; Carbachol; Cattle; Chlorides; Dose-Response Rel | 1986 |
Correlative studies on the effect of carbachol on myo-inositol trisphosphate accumulation, myosin light chain phosphorylation and contraction in sphincter smooth muscle of rabbit iris.
Topics: Animals; Atropine; Calcium; Carbachol; Ethers; Female; Inositol 1,4,5-Trisphosphate; Inositol Phosph | 1986 |
Pharmacology of peptide leukotrienes on ferret isolated airway smooth muscle.
Topics: Animals; Borates; Carbachol; Chromones; Ferrets; In Vitro Techniques; Leukotriene E4; Muscle Contrac | 1986 |
The effects of adenosine on receptor sensitivity in the rat vas deferens.
Topics: Adenosine; Adenosine Triphosphate; Animals; Carbachol; Guinea Pigs; In Vitro Techniques; Male; Muscl | 1986 |
Breakdown of phosphoinositides in airway smooth muscle: lack of influence of anti-asthmatic drugs.
Topics: Animals; Carbachol; Cattle; Dexamethasone; Histamine; Hydrolysis; Isoproterenol; Muscle Contraction; | 1987 |
Relationship between in vivo airway reactivity and in vitro responsiveness of tracheal smooth muscle in inbred rats.
Topics: Airway Resistance; Animals; Carbachol; Dose-Response Relationship, Drug; In Vitro Techniques; Methac | 1988 |
Some properties and mechanisms of thymol-induced release of calcium from the calcium-store in guinea-pig taenia caecum.
Topics: Adenosine Triphosphate; Animals; Calcium; Calcium Radioisotopes; Carbachol; Cecum; Egtazic Acid; Fem | 1986 |
Calcium transients and resting levels in isolated smooth muscle cells as monitored with quin 2.
Topics: Aminoquinolines; Animals; Bufo marinus; Calcium; Carbachol; Cytoplasm; Egtazic Acid; Fluorescent Dye | 1986 |
The inhibitory effects of calmodulin antagonists on the endothelium-dependent relaxation in rabbit aorta.
Topics: Animals; Aorta; Calcimycin; Calmodulin; Carbachol; Endothelium; In Vitro Techniques; Male; Muscle Co | 1986 |
Dissociation of myosin phosphorylation and active tension during muscarinic stimulation of tracheal smooth muscle.
Topics: Atropine; Calcium; Calcium Chloride; Carbachol; Dose-Response Relationship, Drug; Egtazic Acid; Musc | 1987 |
Regional changes in calcium underlying contraction of single smooth muscle cells.
Topics: Animals; Benzofurans; Bufo marinus; Calcium; Carbachol; Electric Stimulation; Fura-2; Kinetics; Musc | 1987 |
Arachidonic acid metabolites and airway epithelium-dependent relaxant factor.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Anti-Inflammatory Agents, Non | 1987 |
Extracellular calcium and human isolated airway muscle: ionophore A23187 induced contraction.
Topics: Calcimycin; Calcium; Carbachol; Histamine; Humans; In Vitro Techniques; Muscle Contraction; Muscle, | 1988 |
The effect of nifedipine on spontaneous, drug-induced and reflexly-activated contractions of the rat urinary bladder: evidence for the participation of an intracellular calcium store to micturition contraction.
Topics: Adenosine Triphosphate; Animals; Arachidonic Acid; Arachidonic Acids; Calcium; Carbachol; Edetic Aci | 1988 |
Effects of thapsigargin in isolated rat thoracic aorta.
Topics: Animals; Aorta, Thoracic; Calcimycin; Carbachol; Endothelium, Vascular; In Vitro Techniques; Male; M | 1988 |
Cholinergic receptors and contraction of smooth muscle in canine portal vein.
Topics: Algorithms; Animals; Calcimycin; Carbachol; Dogs; Guanylyl Imidodiphosphate; Kinetics; Muscle Contra | 1988 |
Free-calcium and force transients during depolarization and pharmacomechanical coupling in guinea-pig smooth muscle.
Topics: Animals; Calcium; Carbachol; Egtazic Acid; Female; Fluorescent Dyes; Guinea Pigs; In Vitro Technique | 1988 |
The intracellular calcium stores in the rabbit trachealis.
Topics: Animals; Caffeine; Calcium; Carbachol; Colforsin; Egtazic Acid; In Vitro Techniques; Muscle Contract | 1988 |
Comparison of the responses to drugs acting on adrenoreceptors and muscarinic receptors in human isolated corpus cavernosum and cavernous artery.
Topics: Acetylcholine; Aged; Carbachol; Clonidine; Electric Stimulation; Ethanolamines; Humans; In Vitro Tec | 1985 |
Desensitization of the isolated bovine iris sphincter muscles by pilocarpine.
Topics: Acetylcholine; Animals; Carbachol; Cattle; Drug Interactions; Drug Tolerance; In Vitro Techniques; I | 1988 |
Regulation of metabolism and contraction by cytoplasmic calcium in the intestinal smooth muscle.
Topics: Anaerobiosis; Animals; Benzofurans; Calcium; Carbachol; Cecum; Deoxyglucose; Fura-2; Glucose; Glycol | 1988 |
Relaxant actions of viprostol and prostaglandin E2 on tracheal muscle and their effects on calcium influx.
Topics: Animals; Calcium; Calcium Chloride; Carbachol; Dinoprostone; Guinea Pigs; Isoproterenol; Macaca fasc | 1988 |
Characteristics of canine lower esophageal sphincter: a new electrophysiological tool.
Topics: Animals; Carbachol; Cimetidine; Dogs; Electric Stimulation; Electrophysiology; Esophagus; Female; Hi | 1988 |
Inhibitory effects of procaine on contraction and calcium movement in vascular and intestinal smooth muscles.
Topics: Animals; Caffeine; Calcium; Calcium Channel Agonists; Carbachol; Histamine; In Vitro Techniques; Mal | 1988 |
Potentiation of contraction of rabbit airway smooth muscle by some cyclooxygenase products.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Bronchi; Carbachol; Din | 1988 |
The effect of acetylcholinesterase-inhibition on the tonus of guinea-pig bronchial smooth muscle.
Topics: Acetylcholinesterase; Animals; Bronchi; Butyrylcholinesterase; Carbachol; Carboxylesterase; Carboxyl | 1988 |
In vivo exposure to ozone causes increased in vitro responses of small airways.
Topics: Animals; Bronchi; Carbachol; Dogs; Histamine; In Vitro Techniques; Muscle Contraction; Ozone; Phorbo | 1988 |
Sites phosphorylated in myosin light chain in contracting smooth muscle.
Topics: Animals; Binding Sites; Carbachol; Cattle; Muscle Contraction; Muscle, Smooth; Myosin-Light-Chain Ki | 1988 |
The use of the internal perimeter to compare airway size and to calculate smooth muscle shortening.
Topics: Carbachol; Epithelium; Humans; Muscle Contraction; Muscle, Smooth; Theophylline; Trachea | 1988 |
Antimuscarinic oxotremorine analogs distinguish high and low affinity agonist states of muscarinic receptors.
Topics: Animals; Binding, Competitive; Carbachol; Cerebral Cortex; Guinea Pigs; Ileum; In Vitro Techniques; | 1988 |
Effects of 5,7,2',5'-tetraacetoxy-4-phenylcoumarin in guinea pig tracheal preparations.
Topics: Animals; Calcium; Carbachol; Coumarins; Female; Guinea Pigs; Leukotriene Antagonists; Male; Muscle C | 1988 |
Responsiveness of normal and dystrophic avian muscle to acetylcholine, carbamylcholine and d-tubocurarine.
Topics: Acetylcholine; Acetylcholinesterase; Animals; Carbachol; Chickens; Female; In Vitro Techniques; Male | 1988 |
Relationship between transmural potential difference and smooth muscle slow waves and contractility in the rabbit small intestine in vitro.
Topics: Animals; Atropine; Carbachol; Electrophysiology; Epinephrine; Intestine, Small; Male; Muscle Contrac | 1988 |
Different immunological sensitizing regimens and airway responsiveness in vitro to contractile agonists in guinea-pigs.
Topics: Animals; Carbachol; Guinea Pigs; Histamine; Immunization; In Vitro Techniques; Lung; Male; Muscle Co | 1988 |
Neuropeptide Y: prejunctional inhibition of vagally induced contractions in the guinea pig trachea.
Topics: Animals; Carbachol; Dose-Response Relationship, Drug; Electric Stimulation; Guinea Pigs; Male; Muscl | 1988 |
[Effect of vasoactive intestinal peptide on the motility of guinea-pig colon in vitro].
Topics: Animals; Atropine; Carbachol; Colon; Gastrointestinal Motility; Guinea Pigs; In Vitro Techniques; Ma | 1988 |
Possible mechanisms related to contraction of the bovine iris sphincter in the presence of acetylcholine and carbachol.
Topics: Acetylcholine; Animals; Carbachol; Cattle; Dose-Response Relationship, Drug; Indomethacin; Iris; Mus | 1988 |
The effects of isoproterenol on intracellular calcium concentration.
Topics: Animals; Atropine; Calcium; Carbachol; Cattle; Colforsin; Isoproterenol; Muscle Contraction; Muscle, | 1988 |
Increased responsiveness of jejunal longitudinal muscle in Trichinella-infected rats.
Topics: Animals; Calcium; Carbachol; Extracellular Space; Jejunum; Male; Muscle Contraction; Muscle, Smooth; | 1988 |
Electrical correlate of circumferential contractions in human colonic circular muscle.
Topics: Action Potentials; Carbachol; Colon; Gastrointestinal Motility; Humans; In Vitro Techniques; Muscle | 1988 |
Contractile effects of manganese on taenia of guinea pig cecum.
Topics: Animals; Calcium; Carbachol; Cecum; Colon; Guinea Pigs; In Vitro Techniques; Kinetics; Male; Mangane | 1988 |
Use of ryanodine for functional removal of the calcium store in smooth muscle cells of the guinea-pig.
Topics: Alkaloids; Animals; Arteries; Benzofurans; Caffeine; Calcium; Carbachol; Colon; Fluorescent Dyes; Fu | 1988 |
Pharmacological analysis of nicotinic relaxation of bovine retractor penis muscle.
Topics: Acetylcholine; Animals; Carbachol; Cattle; Dimethylphenylpiperazinium Iodide; Dose-Response Relation | 1988 |
Relationship between smooth muscle volume and contractile response in airway tissue. Isometric versus isotonic measurement.
Topics: Animals; Bronchi; Carbachol; Histamine; In Vitro Techniques; Isometric Contraction; Muscle Contracti | 1988 |
[Pharmacological characterizations of the in vitro anaphylactic contraction of the guinea-pig esophageal muscularis mucosae].
Topics: Anaphylaxis; Animals; Calcium; Carbachol; Esophagus; Female; Guinea Pigs; In Vitro Techniques; Mucou | 1988 |
Effects of cholecystokinin octapeptide on contractile motility of guinea pig common bile duct.
Topics: Animals; Carbachol; Common Bile Duct; Dose-Response Relationship, Drug; Electric Stimulation; Female | 1988 |
Chiral muscarinic agonists possessing a 1,3-oxathiolane nucleus: enantio- and tissue-selectivity on isolated preparations of guinea-pig ileum and atria and of rat urinary bladder.
Topics: Animals; Binding, Competitive; Carbachol; Guinea Pigs; Heart; Heterocyclic Compounds; Ileum; In Vitr | 1988 |
Paradoxical effects of La3+ on the Na+-loaded ureter and taenia coli smooth muscles of the guinea pig.
Topics: Animals; Caffeine; Carbachol; Colon; Drug Synergism; Female; Guinea Pigs; In Vitro Techniques; Lanth | 1988 |
Inhibition of tracheal smooth muscle contraction and myosin phosphorylation by ryanodine.
Topics: Alkaloids; Animals; Caffeine; Calcium; Calcium Channel Blockers; Calcium Radioisotopes; Carbachol; D | 1988 |
Relaxant effect of amiloride on canine tracheal smooth muscle.
Topics: Airway Resistance; Amiloride; Animals; Carbachol; Dogs; Female; In Vitro Techniques; Male; Muscle Co | 1988 |
Verapamil-sensitive and less sensitive contractions in the intestinal smooth muscle of the guinea-pig taenia caeci.
Topics: Animals; Calcium Channel Blockers; Carbachol; Cecum; Guinea Pigs; In Vitro Techniques; Intestines; M | 1988 |
Enantioselectivity of muscarinic antagonists. 2,2-Dicyclohexyl-5-[(dimethylamino)methyl]-1,3-oxathiolane methiodides and related 3-oxides.
Topics: Animals; Atrial Function; Carbachol; Chemical Phenomena; Chemistry; Cyclohexanes; Guinea Pigs; Heart | 1988 |
Measurement of cytoplasmic free Ca2+ concentration in bovine tracheal smooth muscle using aequorin.
Topics: Aequorin; Animals; Atropine; Caffeine; Calcium; Calcium Channel Blockers; Carbachol; Cattle; Cytopla | 1987 |
Temporal changes in mechanical properties of rat jejunal smooth muscle after myenteric plexus ablation.
Topics: Animals; Barium; Benzalkonium Compounds; Biomechanical Phenomena; Carbachol; In Vitro Techniques; Je | 1987 |
Progesterone inhibits the contractile motility of the guinea pig gallbladder.
Topics: Animals; Calcium Chloride; Carbachol; Gallbladder; Guinea Pigs; Histamine; In Vitro Techniques; Male | 1987 |
Antimuscarinic action of methoctramine, a new cardioselective M-2 muscarinic receptor antagonist, alone and in combination with atropine and gallamine.
Topics: Animals; Atropine; Carbachol; Diamines; Drug Interactions; Gallamine Triethiodide; Guinea Pigs; Hear | 1987 |
Acetylene compounds of potential pharmacological value. XL. N-(tert-aminoalkynyl)-substituted 3-isothiazolidinone-1,1-dioxides and tetrahydro-1,2-thiazin-3-one-1,1-dioxides.
Topics: Animals; Anticonvulsants; Benzopyrans; Carbachol; Chemical Phenomena; Chemistry; Chromans; Cyclic S- | 1987 |
Interaction of himbacine with carbachol at muscarinic receptors of heart and smooth muscle.
Topics: Alkaloids; Animals; Carbachol; Female; Furans; Guinea Pigs; Heart; Heart Rate; In Vitro Techniques; | 1987 |
Cardioselective antimuscarinic action of a dopamine receptor agonist, N,N-dipropyl-2-aminotetralin (TL-68).
Topics: Animals; Atropine; Carbachol; Guinea Pigs; Heart; In Vitro Techniques; Male; Muscle Contraction; Mus | 1987 |
[Infusing drug concentration- and speed-response curves].
Topics: Acetylcholine; Animals; Carbachol; Dose-Response Relationship, Drug; Guinea Pigs; In Vitro Technique | 1987 |
Protein kinase C regulates smooth muscle tension in guinea-pig trachea and ileum.
Topics: Animals; Calcium Channel Blockers; Carbachol; Dinoprost; Guinea Pigs; Ileum; Muscle Contraction; Mus | 1986 |
Muscle tone and drug sensitivity of isolated bovine iris sphincter are enhanced at low temperatures.
Topics: Animals; Carbachol; Cattle; Dinoprostone; Indomethacin; Iris; Muscle Contraction; Muscle Tonus; Pros | 1987 |
6-Methyl-6-azabicyclo[3.2.1]octan-3 alpha-ol 2,2-diphenylpropionate (azaprophen), a highly potent antimuscarinic agent.
Topics: Acetylcholine; alpha-Amylases; Animals; Behavior, Animal; Carbachol; Cell Line; Chemical Phenomena; | 1987 |
M2 muscarinic receptor subtype is associated with inositol trisphosphate accumulation, myosin light chain phosphorylation and contraction in sphincter smooth muscle of rabbit iris.
Topics: Animals; Atropine; Carbachol; Female; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Inositol Ph | 1987 |
Dissociation of contraction and muscarinic receptor binding to isolated smooth muscle cells.
Topics: Animals; Atropine; Binding, Competitive; Carbachol; Dogs; Kinetics; Methacholine Chloride; Methachol | 1986 |
Muscarinic and antimuscarinic activity of acetamides related to oxotremorine in the guinea pig urinary bladder.
Topics: Acetamides; Animals; Carbachol; Guinea Pigs; In Vitro Techniques; Kinetics; Male; Muscle Contraction | 1987 |
Effect of pancreatic polypeptide on the motility of the guinea-pig small intestine in vitro.
Topics: Animals; Carbachol; Female; Gastrointestinal Motility; Guinea Pigs; In Vitro Techniques; Intestine, | 1986 |
Effects of cooling on the contractile response of the rat tracheal muscle to pilocarpine in vitro.
Topics: Animals; Atropine; Calcium; Carbachol; Cold Temperature; In Vitro Techniques; Male; Muscle Contracti | 1987 |
Early production of 1,4,5-inositol trisphosphate and 1,3,4,5-inositol tetrakisphosphate by histamine and carbachol in ileal smooth muscle.
Topics: Animals; Carbachol; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Guinea P | 1987 |
Acute and sub-acute inhalation of an organophosphate induce alteration of cholinergic muscarinic receptors.
Topics: Acetylcholine; Acetylcholinesterase; Administration, Inhalation; Animals; Carbachol; Lung; Male; Mus | 1987 |
Different spasmolytic effects of smooth muscle relaxants on the guinea-pig esophageal muscularis mucosae contracted by carbachol or high potassium in vitro.
Topics: Animals; Carbachol; Catecholamines; Esophagus; Guinea Pigs; In Vitro Techniques; Male; Muscle Contra | 1987 |
Blockade by theophylline of capsaicin-induced motor effects in guinea-pig airways.
Topics: Acetylcholine; Animals; Bronchi; Capsaicin; Carbachol; Dose-Response Relationship, Drug; Guinea Pigs | 1987 |
Effects of aerosol antigen challenge in vivo on responsiveness of guinea pig tracheal and parenchymal strips in vitro to contractile agonists.
Topics: Aerosols; Animals; Antigens; Carbachol; Guinea Pigs; Histamine; In Vitro Techniques; Male; Muscle Co | 1987 |
Isoarecolone can inhibit nicotine binding and produce nicotine-like discriminative stimulus effects in rats.
Topics: Animals; Anura; Arecoline; Brain; Carbachol; Discrimination, Psychological; Male; Muscle Contraction | 1987 |
Source of calcium for contractions induced by depolarization and muscarinic receptor stimulation in rabbit urinary bladder.
Topics: Animals; Calcium; Calcium Channel Blockers; Carbachol; Female; Gallopamil; Lanthanum; Muscle Contrac | 1987 |
The time-course of contractions induced by acetylcholine and barium in the vas deferens of normal and castrated guinea-pigs.
Topics: Acetylcholine; Animals; Barium; Barium Compounds; Carbachol; Castration; Chlorides; Guinea Pigs; Iso | 1986 |
Effects of cholinergic drugs on muscle contraction in Moniliformis moniliformis (Acanthocephala).
Topics: Acanthocephala; Acetylcholine; Acetylcholinesterase; Animals; Butyrylcholinesterase; Carbachol; Chol | 1987 |
The effect of non-isotonic solutions on human isolated airway smooth muscle.
Topics: Bronchi; Carbachol; Electric Stimulation; Female; Histamine; Humans; Hypertonic Solutions; Hypotonic | 1987 |
The physiological response of the detrusor muscle to experimental bladder outflow obstruction in the pig.
Topics: Acetylcholine; Animals; Carbachol; Disease Models, Animal; Dose-Response Relationship, Drug; Muscle | 1987 |
Quantitative measurement of smooth muscle shortening in isolated pig trachea.
Topics: Airway Resistance; Animals; Carbachol; Cartilage; In Vitro Techniques; Mathematics; Muscle Contracti | 1987 |
Ultrastructure of single smooth muscle cells contracted by carbachol and calcium ion.
Topics: Animals; Calcium; Carbachol; Guinea Pigs; Male; Microscopy, Electron; Microscopy, Electron, Scanning | 1987 |
Local parasympathetic mechanisms for ragweed-sensitized canine trachealis hyperresponsiveness.
Topics: Acetylcholine; Animals; Carbachol; Dogs; Dose-Response Relationship, Drug; Electric Stimulation; Hyp | 1987 |
Formyl-methionyl-leucyl-phenylalanine causes bronchoconstriction in rabbits.
Topics: Animals; Bronchi; Carbachol; Female; Histamine; In Vitro Techniques; Kinetics; Leukocyte Count; Lung | 1986 |
Mechanisms of the inhibition by neostigmine of tetanic contraction in the mouse diaphragm.
Topics: Action Potentials; Animals; Carbachol; Diaphragm; Electric Stimulation; Female; Isometric Contractio | 1986 |
A study of the contractile response to acetylcholine in human ileal and detrusor muscle: origin of the low efficacy of acetylcholine.
Topics: Acetylcholine; Animals; Carbachol; Guinea Pigs; Humans; Ileum; In Vitro Techniques; Muscle Contracti | 1986 |
In vitro effects of soman on bronchial smooth muscle.
Topics: Acetylcholine; Acetylcholinesterase; Animals; Bronchi; Carbachol; Carboxylic Ester Hydrolases; Choli | 1986 |
Actions and interactions of adenosine, theophylline and enprofylline on the guinea-pig spirally cut trachea.
Topics: Adenosine; Animals; Bronchodilator Agents; Carbachol; Drug Interactions; Female; Guinea Pigs; Histam | 1986 |
Membrane and contractile properties of the dog ciliary muscle.
Topics: Animals; Carbachol; Dogs; Electric Stimulation; Evoked Potentials; Female; In Vitro Techniques; Isom | 1986 |
Quantification of the actions of agonists that simultaneously act on a particular type of receptor and have separate functional interactant properties.
Topics: Animals; Carbachol; In Vitro Techniques; Jejunum; Male; Muscle Contraction; Muscle, Smooth; Papaveri | 1986 |
The calcium dependence of histamine, carbachol and potassium chloride-induced contraction in human airways in vitro.
Topics: Bronchi; Calcium; Calcium Channel Blockers; Carbachol; Gallic Acid; Histamine; Humans; In Vitro Tech | 1986 |
Effect of calcium antagonist darodipine on the isolated human heart.
Topics: Calcium; Calcium Channel Blockers; Carbachol; Coronary Vessels; Heart; Histamine; Humans; In Vitro T | 1986 |
Effects of milrinone on contractile responses of guinea pig trachea, lung parenchyma and pulmonary artery.
Topics: Aminophylline; Animals; Carbachol; Cardiotonic Agents; Dose-Response Relationship, Drug; Guinea Pigs | 1986 |
Activation of smooth muscle contraction: relation between myosin phosphorylation and stiffness.
Topics: Animals; Carbachol; Electric Stimulation; In Vitro Techniques; Kinetics; Muscle Contraction; Muscle, | 1986 |
Altered calcium-handling properties of jejunal smooth muscle from the nematode-infected rat.
Topics: Animals; Calcium; Carbachol; In Vitro Techniques; Intestinal Diseases, Parasitic; Jejunum; Male; Mus | 1986 |
The responsiveness of rabbit bronchial rings to antigen, AGEPC and histamine.
Topics: Animals; Antigens; Atropine; Bronchi; Carbachol; Chlorpheniramine; Female; Histamine; Immunoglobulin | 1986 |
Physiological and pharmacological characterization of an in vitro vagus nerve-trachea preparation from guinea-pig.
Topics: Animals; Atropine; Carbachol; Electric Stimulation; Guinea Pigs; Hexamethonium Compounds; In Vitro T | 1986 |
Presynaptic inhibitory muscarinic receptors modulating [3H] acetylcholine release in the rat urinary bladder.
Topics: Acetylcholine; Animals; Atropine; Calcium; Carbachol; Hemicholinium 3; Male; Muscarine; Muscle Contr | 1986 |
Inhibition of calcium channels by harmaline and other harmala alkaloids in vascular and intestinal smooth muscles.
Topics: Adenosine Triphosphate; Alkaloids; Animals; Aorta, Thoracic; Calcium; Calcium Channel Blockers; Carb | 1986 |
Carbachol-induced protein phosphorylation changes in bovine tracheal smooth muscle.
Topics: Animals; Calcium; Calmodulin-Binding Proteins; Carbachol; Cattle; Colforsin; Cytosol; Desmin; Interm | 1986 |
Estimation of apparent agonist affinity constants using desensitization of the ileal muscarinic receptor.
Topics: Animals; Biological Assay; Calcium; Carbachol; Dose-Response Relationship, Drug; Female; Guinea Pigs | 1987 |
Effect of duration of stimulation on mechanical properties of trachealis muscle.
Topics: Animals; Carbachol; Dogs; Elasticity; Electric Stimulation; Isometric Contraction; Muscle Contractio | 1986 |
Smooth muscle inhibition by an extract of Sesbania drummondii.
Topics: Animals; Aorta; Carbachol; Chickens; Dose-Response Relationship, Drug; Histamine; Ileum; In Vitro Te | 1987 |
Mechanisms of response to antigen in isolated guinea pig trachea after active sensitization.
Topics: Animals; Antigens; Carbachol; Guinea Pigs; Histamine; In Vitro Techniques; Male; Muscle Contraction; | 1986 |
[Mechanographic profile of guinea pig intestine. Relaxation].
Topics: Animals; Carbachol; Guinea Pigs; Intestines; Muscle Contraction; Muscle Relaxation | 1985 |
A search for selective antagonists at M2 muscarinic receptors.
Topics: Animals; Atrial Function; Carbachol; Chemical Phenomena; Chemistry; Guinea Pigs; Heart Rate; Ileum; | 1985 |
Effects of sodium vanadate on the smooth muscle of the guinea-pig vas deferens.
Topics: Animals; Calcium; Carbachol; Drug Synergism; Guinea Pigs; In Vitro Techniques; Male; Membrane Potent | 1985 |
Effect of drugs and electrical field stimulation on circular muscle strips from human lower oesophagus.
Topics: Carbachol; Dinoprost; Electric Stimulation; Esophagogastric Junction; Humans; In Vitro Techniques; M | 1985 |
The relative potencies of some agonists at M2 muscarinic receptors in guinea-pig ileum, atria and bronchi.
Topics: Acetylcholine; Animals; Arecoline; Atrial Function; Bronchi; Carbachol; Choline; Guinea Pigs; Heart | 1985 |
Contraction and relaxation induced by some prostanoids in isolated human penile erectile tissue and cavernous artery.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Aged; Arteries; Carbachol; Dinop | 1985 |
Receptor operated intracellular calcium stores in the smooth muscle of the guinea pig bladder.
Topics: Animals; Calcium; Carbachol; Colon; Egtazic Acid; Guinea Pigs; In Vitro Techniques; Male; Muscle Con | 1985 |
Carbachol-induced contraction in the circular muscle of guinea-pig stomach in calcium-free solution.
Topics: Animals; Calcium; Calmodulin; Carbachol; Dose-Response Relationship, Drug; Female; Guinea Pigs; In V | 1986 |
Selective effect of nortriptyline on smooth muscle as an anticholinergic drug: a pharmacological and clinical study.
Topics: Bethanechol Compounds; Carbachol; Dose-Response Relationship, Drug; Female; Humans; Ileum; Muscle Co | 1986 |
Electrical basis of excitation and inhibition of human colonic smooth muscle.
Topics: Action Potentials; Carbachol; Colon; Electrodes; Humans; In Vitro Techniques; Isoproterenol; Membran | 1986 |
Calcium dependence of myosin phosphorylation and airway smooth muscle contraction and relaxation.
Topics: Acetylcholine; Animals; Atropine; Calcium; Calcium Chloride; Carbachol; Dogs; Dose-Response Relation | 1986 |
Mechanical activity of muscular "patch pouches" from cat and rabbit stomachs.
Topics: Adaptation, Physiological; Animals; Biomechanical Phenomena; Carbachol; Cats; Electric Stimulation; | 1985 |
Synthesis and LTD4-antagonist activity of desamino-2-nor-leukotriene analogs.
Topics: Animals; Carbachol; Guinea Pigs; Indicators and Reagents; Meclofenamic Acid; Muscle Contraction; SRS | 1985 |
Age-related changes in guinea pig respiratory tissues: considerations for assessment of bronchodilators.
Topics: Age Factors; Albuterol; Animals; Bronchi; Bronchodilator Agents; Carbachol; Catechol O-Methyltransfe | 1985 |
Effect of cholinergic agonists on muscle from rodent proximal and distal small intestine.
Topics: Acetylcholine; Animals; Bethanechol Compounds; Carbachol; Dose-Response Relationship, Drug; In Vitro | 1985 |
Kerosene aerosol induces guinea-pig airway hyperreactivity to acetylcholine.
Topics: Acetylcholine; Aerosols; Animals; Carbachol; Drug Synergism; Female; Guinea Pigs; Histamine; Kerosen | 1985 |
Effects of botulinum toxin on synapse formation and acetylcholine sensitivity in skeletal muscle in the newt.
Topics: Acetylcholine; Animals; Botulinum Toxins; Carbachol; Drug Resistance; Electric Stimulation; Intracel | 1985 |
Myosin phosphorylation and contraction of feline esophageal smooth muscle.
Topics: Animals; Carbachol; Cats; Electric Stimulation; Esophagus; In Vitro Techniques; Isometric Contractio | 1985 |
Relationship between stimulated inositol lipid hydrolysis and contractility in guinea-pig visceral longitudinal smooth muscle.
Topics: Animals; Calcium; Carbachol; Dose-Response Relationship, Drug; Female; Guinea Pigs; Hydrolysis; In V | 1985 |
Effect of adenosine 5'triphosphate (ATP) on the isolated rectum of the rainbow lizard Agama agama.
Topics: Adenosine Triphosphate; Animals; Calcium; Calcium Chloride; Carbachol; Dipyridamole; In Vitro Techni | 1985 |
Muscarinic acetylcholine receptors in the rabbit ciliary body smooth muscle: spare receptors and threshold phenomenon.
Topics: Animals; Arecoline; Atropine; Carbachol; Ciliary Body; In Vitro Techniques; Male; Muscle Contraction | 1985 |
Contractile responses to histamine of isolated pulmonary artery strips from healthy and heartworm-infected dogs.
Topics: Animals; Carbachol; Dirofilariasis; Dog Diseases; Dogs; Histamine; Muscle Contraction; Muscle, Smoot | 1985 |
Quantification of the characteristics of antagonists exhibiting both competitive antagonism and functional interaction.
Topics: Animals; Atropine; Binding, Competitive; Carbachol; Drug Antagonism; Drug Interactions; Guinea Pigs; | 1985 |
Mode of stimulatory actions of cadmium ion on the mouse diaphragm.
Topics: Acetylcholine; Animals; Cadmium; Calcium; Carbachol; Cations; Cell Membrane Permeability; Cysteine; | 1985 |
Interaction of amoxapine with muscarinic cholinergic receptors: an in vitro assessment.
Topics: Acetylcholine; Amoxapine; Animals; Antidepressive Agents; Binding, Competitive; Brain; Carbachol; Di | 1985 |
Myosin phosphorylation, force, and maximal shortening velocity in neurally stimulated tracheal smooth muscle.
Topics: Animals; Atropine; Carbachol; Cattle; Electric Stimulation; Isometric Contraction; Kinetics; Muscle | 1985 |
Transient inhibition of the muscarinic actions of carbachol during reactivation of the electrogenic sodium pump in guinea pig taenia caeci smooth muscle.
Topics: Animals; Biological Transport, Active; Carbachol; Cecum; Female; Guinea Pigs; In Vitro Techniques; I | 1985 |
Examination of the bronchoconstrictor response of guinea-pig isolated lung to beta-phenylethylamine.
Topics: Animals; Atropine; Bronchi; Carbachol; Dopamine; Drug Interactions; Female; Guinea Pigs; Histamine; | 1985 |
Pharmacological characterization of the histamine receptor in the isolated muscularis mucosae of the guinea-pig oesophagus.
Topics: Animals; Calcium; Carbachol; Esophagus; Guinea Pigs; Histamine; Histamine Antagonists; In Vitro Tech | 1985 |
Are there valid reasons for using anti-muscarinic drugs in the management of renal colic?
Topics: Barium; Barium Compounds; Carbachol; Chlorides; Colic; Dose-Response Relationship, Drug; Female; Hum | 1985 |
Effect of Rumex nepalensis extracts on histamine, acetylcholine and carbachol evoked responses on isolated guinea pig ileum, frog rectus abdominis muscle, rabbit heart and blood pressure of dog.
Topics: Acetylcholine; Animals; Blood Pressure; Bradykinin; Carbachol; Dogs; Guinea Pigs; Hemodynamics; Hist | 1985 |
Effects of chronic drug treatment on the sensitivity of mouse vas deferens to drugs.
Topics: Animals; Carbachol; Clonidine; Electric Stimulation; In Vitro Techniques; Male; Mice; Morphine; Musc | 1985 |
The stimulative effect of sodium on the depletion process of calcium in the intracellular store of smooth muscle cells of guinea-pig taenia caecum.
Topics: Animals; Calcium; Calcium Radioisotopes; Carbachol; Cecum; Female; Guinea Pigs; In Vitro Techniques; | 1985 |
[Influence of temperature on the carbachol contraction of the smooth muscle of the guinea pig trachea].
Topics: Animals; Carbachol; Dose-Response Relationship, Drug; Guinea Pigs; In Vitro Techniques; Male; Muscle | 1985 |
[Animal experimental studies on a protease from Aspergillus ochraceus].
Topics: Animals; Aspergillus; Barium; Blood Pressure; Carbachol; Carotid Arteries; Chlorides; Female; Heart; | 1974 |
Relationship between cyclic AMP, phosphodiesterase activity, calcium and contraction in intestinal smooth muscle.
Topics: Adrenergic beta-Antagonists; Animals; Atropine; Calcium; Carbachol; Colon; Cyclic AMP; Drug Synergis | 1973 |
Action of acetylcholine on the longitudinal muscle of guinea-pig ileum: the role of an electrogenic sodium pump.
Topics: Acetylcholine; Animals; Biological Transport; Carbachol; Guinea Pigs; Ileum; Mathematics; Membrane P | 1973 |
Studies on the stereospecificity of closely related compounds which block postganglionic acetylcholine receptors in the guinea-pig ileum.
Topics: Animals; Autonomic Fibers, Postganglionic; Carbachol; Dose-Response Relationship, Drug; Ganglionic B | 1973 |
Effect of local anesthetics on pharmacologic receptor systems of smooth muscle.
Topics: Adrenergic alpha-Antagonists; Anesthetics, Local; Animals; Aorta, Thoracic; Atropine; Carbachol; Dib | 1973 |
Effects of oxyfedrine on isolated portal vein and other smooth muscles.
Topics: Adrenergic beta-Agonists; Amino Alcohols; Animals; Calcium Chloride; Carbachol; Dogs; Duodenum; Fema | 1973 |
1,4-Benzodioxanes as reversible and irreversible antagonists at adrenergic receptors.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Binding Sites; Calcium; Carbacho | 1974 |
Contractile responses to phenylephrine and carbachol in circular rabbit fundus strips at varying external K+ AND Ca++ concentrations.
Topics: Adrenergic alpha-Agonists; Animals; Calcium; Carbachol; Depression, Chemical; Dose-Response Relation | 1973 |
Factors influencing observed beta-adrenergic receptor antagonism in guinea-pig trachea.
Topics: Adrenergic beta-Antagonists; Animals; Carbachol; Catechol O-Methyltransferase Inhibitors; Dose-Respo | 1974 |
Conditions affecting the interaction of cholinergic agents on the longitudinal muscle of the guinea-pig ileum--unexpected effects with hexamethonium.
Topics: Animals; Atropine; Carbachol; Drug Interactions; Guinea Pigs; Hexamethonium Compounds; Ileum; In Vit | 1974 |
The effects of arachidonic acid, prostaglandin E2 and prostaglandin F2alpha on the longitudinal stomach strip of the rat.
Topics: Acetylcholine; Animals; Arachidonic Acids; Atropine; Carbachol; Dose-Response Relationship, Drug; Fa | 1973 |
[On the quantitative relationship between contractile response and sensitivity decrease caused by different parasympathomimetic drugs].
Topics: Amino Alcohols; Animals; Carbachol; Guinea Pigs; Ileum; In Vitro Techniques; Muscle Contraction; Mus | 1968 |
[Characterization of a biphasic response of the chronically denervated rat diaphragm to acetylcholine and carbamylcholine].
Topics: Acetylcholine; Animals; Carbachol; Diaphragm; In Vitro Techniques; Muscle Contraction; Muscle Denerv | 1970 |
Characterization of a biphasic response of the chronically denervated diaphragm of the rat to the same cholinergic agonist.
Topics: Acetylcholine; Animals; Carbachol; Diaphragm; Electrophysiology; Male; Muscle Contraction; Muscle De | 1971 |
Neuromuscular blocking action of 2-(2-(3-pyridyl) vinyl)-3-0-tolyl-3, 4-dihydroquinazoline-4-one (SRC 909).
Topics: Abdominal Muscles; Acetylcholine; Animals; Anura; Atropine; Calcium; Carbachol; Cats; Choline; Cold | 1974 |
The pharmacology of the cardiac muscle of the great veins of the rat.
Topics: Acetylcholine; Action Potentials; Angiotensin II; Animals; Atrial Function; Atropine; Carbachol; Ele | 1967 |
Tetraethylammonium-induced contractions of frog's skeletal muscle. 3. Mechanism of action by calcium release.
Topics: Animals; Anura; Calcium; Carbachol; Electrophysiology; Muscle Contraction; Nerve Endings; Potassium; | 1967 |
Differentiation of various types of cholinergic and other spasmogenic actions on the isolated guinea-pig ileum.
Topics: Acetylcholine; Animals; Barium; Carbachol; Guinea Pigs; Histamine; Ileum; Models, Biological; Muscle | 1968 |
Mechanism of neuromuscular blockade by tetraethylammonium.
Topics: Action Potentials; Animals; Anura; Carbachol; Cell Membrane; In Vitro Techniques; Iontophoresis; Mem | 1969 |
Pharmacological properties of feline red nucleus.
Topics: Acetylcholine; Amines; Amino Acids; Aminobutyrates; Animals; Carbachol; Cats; Dopamine; Electrophore | 1969 |
The effect of adrenergic drugs on the isolated tracheal tube in vitro and on the bronchial resistance to inflation in vivo.
Topics: Acetanilides; Acetylcholine; Animals; Bronchi; Carbachol; Cats; Constriction; Creatinine; Cyclic AMP | 1969 |
Antagonism of smooth muscle contractility by catecholamines.
Topics: Acetylcholine; Animals; Carbachol; Electric Stimulation; Electrodes; Ganglia, Autonomic; In Vitro Te | 1970 |
Autonomic control of cardiac C-AMP.
Topics: Adenine Nucleotides; Adenylyl Cyclases; Animals; Atrial Function; Atropine; Carbachol; Carbon Isotop | 1971 |
The effect of tetanus toxin at the neuromuscular junction in the goldfish.
Topics: Acetylcholine; Animals; Carbachol; Cyprinidae; Electric Stimulation; Membrane Potentials; Muscle Con | 1972 |
Spontaneous transmitter release and ACh sensitivity during glutaraldehyde fixation of rat diaphragm.
Topics: Acetylcholine; Action Potentials; Aldehydes; Animals; Carbachol; Cell Membrane; Diaphragm; Glutarate | 1972 |
Role of cyclic AMP and Ca++ in metabolic and mechanical events in smooth muscle.
Topics: Adenosine Triphosphate; Animals; Barium; Calcium; Calcium Isotopes; Carbachol; Colon; Corticosterone | 1972 |
The sucrose-gap technique. Autonomic drugs and electrical characteristics of the ureter.
Topics: Acetylcholine; Action Potentials; Animals; Atropine; Carbachol; Cell Membrane; In Vitro Techniques; | 1973 |
Studies on the tachyphylaxis to nicotinic stimulant drugs in the perfused hypogastric ganglion of the guinea-pig.
Topics: Animals; Atropine; Carbachol; Chlorides; Dimethylphenylpiperazinium Iodide; Electric Stimulation; El | 1974 |
Presynaptic and postsynaptic effects of the venom of the Australian tiger snake at the neuromuscular junction.
Topics: Acetylcholine; Action Potentials; Animals; Antivenins; Bufo marinus; Calcium; Carbachol; Chemorecept | 1973 |
Release of prostaglandins from the rabbit renal medulla.
Topics: Angiotensin II; Animals; Atropine; Bradykinin; Carbachol; Diphenhydramine; Dose-Response Relationshi | 1974 |
Ouabain-induced potentiation on the contractions of the guinea-pig vas deferens.
Topics: Acetylcholine; Angiotensin II; Animals; Binding Sites; Carbachol; Cocaine; Denervation; Dose-Respons | 1974 |
The effect of metronidazole on striated muscle.
Topics: Acetylcholine; Animals; Carbachol; Cholinesterase Inhibitors; Diaphragm; Drug Synergism; Electric St | 1974 |
Alterations in pharmacologic receptor activity by dithiothreitol.
Topics: Angiotensin II; Animals; Aorta, Thoracic; Benzyl Compounds; Carbachol; Depression, Chemical; Disulfi | 1974 |
Proceedings: The effect of tetraethylammonium (TEA) on the anococcygeus muscle and on its response to motor and to inhibitory nerve stimulation.
Topics: Animals; Atropine; Carbachol; Curare; Dose-Response Relationship, Drug; Drug Synergism; Electric Sti | 1974 |
Inhibitory effect of 1-alkylbenzimidazoles on gastric secretion in the rat.
Topics: Acetylcholine; Animals; Behavior, Animal; Blood Pressure; Bradycardia; Carbachol; Cats; Central Nerv | 1966 |
Electrical and contractile responses of the pyloric region to adrenergic and cholinergic drugs.
Topics: Acetylcholine; Animals; Atropine; Carbachol; Dogs; Drug Antagonism; Duodenum; Electrophysiology; Epi | 1966 |
Antispasmodic ortho-substituted phenoxyalkylamines.
Topics: Amino Alcohols; Animals; Barium; Carbachol; Chemistry, Organic; Drug Antagonism; Ethers; Guinea Pigs | 1966 |
Effects of physostigmine on smooth muscle.
Topics: Acetylcholine; Animals; Anura; Atropine; Biphenyl Compounds; Carbachol; Electric Stimulation; Gangli | 1966 |
Investigation into the mode of action of histamine on the isolated rabbit heart.
Topics: Aminophylline; Animals; Atrial Function; Carbachol; Chemoreceptor Cells; Drug Synergism; Duodenum; E | 1968 |
The effects of drugs on circular muscle strips from the isolated ileum of the rabbit.
Topics: Acetylcholine; Animals; Atropine; Carbachol; Cholinesterase Inhibitors; Cocaine; Drug Antagonism; Fe | 1968 |
The dual mode of action of histamine in the cat isolated tracheal chain.
Topics: Animals; Carbachol; Catecholamines; Cats; Ethanolamines; Histamine; Histamine H1 Antagonists; Muscle | 1968 |
Guanethidine and carbachol on the isolated frog rectus: a non-competitive interaction.
Topics: Animals; Anura; Carbachol; Guanethidine; Muscle Contraction | 1968 |
Pharmacology of new tropine ethers with central activity.
Topics: Acetylcholine; Anesthetics, Local; Animals; Anura; Behavior, Animal; Blood Pressure; Brain Chemistry | 1968 |
Gastric motor-stimulating activity of gastrin tetrapeptide in dogs.
Topics: Animals; Atropine; Blood Pressure; Carbachol; Chlorpromazine; Colon; Dogs; Duodenum; Gastrins; Gastr | 1969 |
Pharmacologic evaluation of a new series of cholinergic antagonists containing an agonist moiety.
Topics: Acetylcholine; Animals; Aorta; Atropine; Benzilates; Carbachol; Chemical Phenomena; Chemistry; Chlor | 1969 |
Excitatory adrenergic receptors in the human stomach and pylorus.
Topics: Acetylcholine; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; | 1969 |
The nature of the adrenergic receptors in isolated human bronchi.
Topics: Acetylcholine; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Bronchi; Carbachol; Drug S | 1969 |
The actions of selective beta-receptor antagonists on the guinea pig trachea.
Topics: Acetanilides; Anilides; Animals; Carbachol; Ergotamine; Ethanolamines; Female; Guinea Pigs; Isoprote | 1970 |
Antibiotics and ureter: II. Dicloxacillin.
Topics: Ampicillin; Animals; Barium; Carbachol; Dicloxacillin; Dogs; Guinea Pigs; Histamine H1 Antagonists; | 1970 |
Dimethyl sulfoxide, a reversible inactivator of receptor-effector systems in the isolated guinea-pig ileum.
Topics: Animals; Calcium; Carbachol; Cryoprotective Agents; Dimethyl Sulfoxide; Guinea Pigs; Histamine H1 An | 1971 |
The actions of depolarizing drugs and antagonists on developing muscle fibres in vitro.
Topics: Acetylcholine; Animals; Carbachol; Chick Embryo; Culture Techniques; Decamethonium Compounds; Membra | 1971 |
The influence of drugs upon 42 K + fluxes in guinea-pig ileum in vitro.
Topics: Acetylcholine; Animals; Atropine; Barium; Carbachol; Epinephrine; Guinea Pigs; Histamine; Histamine | 1972 |
Effect of various drugs on electrical and mechanical parameters of atrial muscle.
Topics: Acetanilides; Action Potentials; Adrenergic beta-Antagonists; Amino Alcohols; Animals; Carbachol; Fe | 1971 |
Effects of CO2 and pH on drug-induced contractions of airway smooth muscle.
Topics: Acetylcholine; Animals; Atropine; Bethanechol Compounds; Bronchi; Calcium; Carbachol; Carbon Dioxide | 1974 |
The in vitro neuromuscular blocking properties of sea snake (Enhydrina schistosa) venom.
Topics: Acetylcholine; Allyl Compounds; Animals; Bufonidae; Carbachol; Denervation; Diaphragm; Dose-Response | 1974 |
[Interaction of N-methyl and N-butyl scopolammonium and some parasympathomimetics on cholinergic receptors in the jejunum of the rat].
Topics: Acetylcholine; Animals; Arecoline; Carbachol; Dose-Response Relationship, Drug; Furans; Humans; In V | 1974 |
Proceedings: The kinetics of action of acetylcholine antagonists on guinea-pig ileum.
Topics: Acetylcholine; Animals; Carbachol; Dose-Response Relationship, Drug; Guinea Pigs; Ileum; In Vitro Te | 1974 |
Proceedings: Voltage-clamp experiments on the potential-dependent behaviour of membrane ion channels operated by the muscarinic receptor of smooth muscle.
Topics: Animals; Carbachol; Female; Guinea Pigs; Ileum; In Vitro Techniques; Membrane Potentials; Muscle Con | 1974 |
Acetylcholine receptors.
Topics: Acetylcholine; Adrenal Medulla; Animals; Anura; Axons; Bungarotoxins; Carbachol; Cell Membrane Perme | 1974 |
Calcium and the contractile effect of carbachol in the depolarized guinea-pig taenia caecum.
Topics: Animals; Atropine; Calcium; Carbachol; Cecum; Dose-Response Relationship, Drug; Drug Synergism; Fema | 1974 |
Response to the rabbit coronary arteries to autonomic agents.
Topics: Acetylcholine; Animals; Arteries; Atropine; Carbachol; Catecholamines; Coronary Vessels; Depression, | 1974 |
On the interaction of acetylcholine, caffeine and altered ca-concentrations upon the excitation-contraction coupling in chronically denervated skeletal muscle.
Topics: Acetylcholine; Animals; Caffeine; Calcium; Calcium Radioisotopes; Carbachol; Diaphragm; Extracellula | 1974 |
Contractility in vitro of ovarian follicles from sheep, and the effects of drugs.
Topics: Acetylcholine; Animals; Carbachol; Corpus Luteum; Epinephrine; Estrus; Female; Histamine; In Vitro T | 1974 |
[Proceedings: Calcium contraction in the depolarized smooth muscles and effects of sodium, lanthanum, manganese and organic calcium competitors on carbachol contraction].
Topics: Animals; Calcium; Carbachol; Guinea Pigs; In Vitro Techniques; Lanthanum; Manganese; Muscle Contract | 1974 |
The antagonistic effects of calcium and potassium on the time course of action of carbamylcholine at the neuromuscular junction.
Topics: Animals; Anura; Binding Sites; Calcium; Carbachol; Electric Conductivity; In Vitro Techniques; Ion E | 1972 |
Effect of cholinergic drugs and barium on oxygen consumption in guinea pig taenia coli.
Topics: Animals; Atropine; Barium; Calcium; Carbachol; Colon; Depression, Chemical; Electrophysiology; Guine | 1972 |
Electrophysiological comparison of the action of oxytocin and carbachol on pregnant mouse myometrium.
Topics: Action Potentials; Animals; Carbachol; Female; In Vitro Techniques; Membrane Potentials; Mice; Muscl | 1973 |
Effects of external Na and Ca on the mouse myometrium in relation to the effects of oxytocin and carbachol.
Topics: Action Potentials; Animals; Calcium; Carbachol; Female; In Vitro Techniques; Ions; Membrane Potentia | 1973 |
Effect of cholinergic drugs on calcium movement in guinea pig taenia coli.
Topics: Acetylcholine; Animals; Atropine; Calcium; Calcium Radioisotopes; Carbachol; Colon; Guinea Pigs; In | 1973 |
Desensitization of smooth muscle cells in the guinea pig taenia coli to prolonged application of carbachol.
Topics: Animals; Calcium; Carbachol; Chlorine; Colon; Guinea Pigs; In Vitro Techniques; Membrane Potentials; | 1973 |
Modification of the mechanical response of the smooth muscles of pregnant mouse myometrium and guinea pig ileum by cadmium and manganese ions.
Topics: Animals; Cadmium; Carbachol; Cations, Divalent; Electrophysiology; Female; Guinea Pigs; Ileum; In Vi | 1974 |
Cholinergic receptor labelling specific irreversible binding of bromoacetylcholine to cholinergic receptors at neuromuscular junctions.
Topics: Acetylcholine; Acetylcholinesterase; Animals; Anura; Blood Proteins; Carbachol; Cattle; Chickens; Ch | 1974 |
Pressure responses to cholinergic and adrenergic agents in the fundus, corpus, and antrum of isolated rabbit stomachs.
Topics: Acetylcholine; Animals; Carbachol; Epinephrine; Female; In Vitro Techniques; Isoproterenol; Isotonic | 1972 |
The effects of different recording conditions on the estimates of affinity constants of antagonists for acetylcholine receptors in the guinea-pig ileum.
Topics: Acetylcholine; Animals; Carbachol; Guinea Pigs; Ileum; In Vitro Techniques; Muscle Contraction; Musc | 1972 |
Reactions of the isolated plaice stomach to applied drugs.
Topics: Acetylcholine; Animals; Atropine; Carbachol; Creatinine; Dose-Response Relationship, Drug; Epinephri | 1972 |
Potassium-efflux and the contractile response to sympathomimetic amines in circular rabbit fundus muscle.
Topics: Animals; Carbachol; Depression, Chemical; Epinephrine; Female; Isoproterenol; Muscle Contraction; Mu | 1972 |
Relative potency of cholinomimetic drugs on the bovine iris sphincter strips.
Topics: Acetylcholine; Animals; Butyrates; Carbachol; Cattle; Choline; Dose-Response Relationship, Drug; Iri | 1973 |
Antagonism at the cholinergic receptor of denervated diaphragm by monoquaternary and bisquaternary nitrogen compounds.
Topics: Acetylcholine; Ambenonium Chloride; Animals; Carbachol; Depression, Chemical; Diaphragm; In Vitro Te | 1973 |
Changes in the sensitivity to cholinomimetic drugs of smooth and cardiac muscle in the rat induced by subacute administration of di-isopropyl phosphorofluoridate.
Topics: Acetylcholine; Acetylcholinesterase; Animals; Blood Pressure; Carbachol; Cholinesterases; Electric S | 1973 |
Effects of quazodine (MJ 1988) on contractions of the isolated hemidiaphragm of the rat and the biventer cervicis muscle of the chick.
Topics: Acetylcholine; Animals; Calcium; Carbachol; Chickens; Diaphragm; Drug Synergism; Electric Stimulatio | 1973 |
Observations on 'fade': a complication of the contractile response of smooth muscle to a large dose of an agonist.
Topics: Acetylcholine; Animals; Calcium; Carbachol; Dose-Response Relationship, Drug; Guinea Pigs; Histamine | 1973 |
Studies on the action of some cholinoceptor agonists on the chick biventer cervicis muscle preparation.
Topics: Acetylcholine; Animals; Carbachol; Chickens; Choline; Cyclohexanols; Decamethonium Compounds; Dimeth | 1973 |
On the responses of the isolated rectum of the rainbow lizard to drugs and electrical field stimulation.
Topics: Acetylcholine; Animals; Atropine; Carbachol; Chickens; Drug Synergism; Electric Stimulation; Female; | 1973 |
Potassium-efflux and the response to carbachol, phenylephrine, adrenaline, noradrenaline, and isoprenaline in rabbit antrum muscle.
Topics: Animals; Carbachol; Depression, Chemical; Epinephrine; Gastrointestinal Motility; Isoproterenol; Mal | 1973 |
The effect of varying external K+ and Ca++ on the increase in 42K-efflux produced by phenylephrine and carbachol in circular rabbit fundus strips.
Topics: Animals; Calcium; Carbachol; Dose-Response Relationship, Drug; Gastrointestinal Motility; Muscle Con | 1973 |
[Structure-activity relationships of isoarecaidine esters].
Topics: Animals; Arecoline; Atropine; Blood Pressure; Carbachol; Depression, Chemical; Dose-Response Relatio | 1973 |
Effects of echothiophate on cholinesterases in cat irides.
Topics: Acetylcholinesterase; Animals; Butyrates; Carbachol; Carbon Radioisotopes; Cats; Choline; Cholineste | 1974 |
Changes in Ca permeability of muscle fibers during desensitization to carbamylcholine.
Topics: Animals; Anura; Calcium; Carbachol; Muscle Contraction; Muscles; Neuromuscular Junction; Potassium | 1974 |
Effects of drugs on 47Ca2+ movements in depolarized longitudinal smooth muscle.
Topics: Acetylcholine; Animals; Calcium; Calcium Radioisotopes; Carbachol; Epinephrine; Guinea Pigs; Histami | 1974 |
The action potential in end-plate and extrajunctional regions of rat skeletal muscle.
Topics: Action Potentials; Animals; Carbachol; Depression, Chemical; Diaphragm; Male; Muscle Contraction; Mu | 1974 |
Pharmacological studies on the bungarotoxins: separation of the fractions and their neuromuscular activity.
Topics: Acetylcholine; Animals; Bungarotoxins; Carbachol; Chick Embryo; Chromatography; Dose-Response Relati | 1974 |
The additive effects of tranquilizers and dopamine on smooth muscle.
Topics: Animals; Carbachol; Chlorpromazine; Dopamine; Dose-Response Relationship, Drug; Drug Synergism; Elec | 1974 |
Prostaglandin antagonism by polymeric phosphates of phloretin and related compounds.
Topics: Animals; Aqueous Humor; Blood Pressure; Carbachol; Depression, Chemical; Diarrhea; Estradiol; Eye Pr | 1971 |
Measurement of drug-receptor dissociation constants of muscarinic agonists on intestinal smooth muscle.
Topics: Acetylcholine; Animals; Carbachol; Dibenzylchlorethamine; Guinea Pigs; Ileum; In Vitro Techniques; I | 1972 |
Some effects of hexamethonium and tetraethylammonium at a neuromuscular junction of the chicken.
Topics: Acetylcholine; Animals; Carbachol; Chickens; Cholinesterase Inhibitors; Cholinesterases; Denervation | 1972 |
[Pharmacological effects on the contraction frequency of isolated rat portal vein].
Topics: Aconitum; Animals; Atropine; Caffeine; Carbachol; Epinephrine; Histamine; In Vitro Techniques; Isopr | 1972 |
Desensitization in the rat myometrium.
Topics: Animals; Calcium; Carbachol; Female; In Vitro Techniques; Membrane Potentials; Muscle Contraction; M | 1972 |
-adrenergic receptor stimulation with phenylephrine in rabbit fundus muscle exposed to carbachol.
Topics: Animals; Carbachol; Female; Muscle Contraction; Muscle Tonus; Muscle, Smooth; Phenylephrine; Rabbits | 1972 |
Agonist-antagonist interaction at the cholinergic receptor of denervated diaphragm.
Topics: Acetylcholine; Animals; Carbachol; Diaphragm; Drug Antagonism; Gallamine Triethiodide; Kinetics; Mal | 1972 |
Pyrrolizidine alkaloids: analysis of spasmolytic activity in the guinea-pig ileum.
Topics: Animals; Barium; Carbachol; Dose-Response Relationship, Drug; Drug Antagonism; Female; Guinea Pigs; | 1972 |
A quantitative study of the anticholinergic action of several tricyclic antidepressants on the rat isolated fundal strip.
Topics: Amitriptyline; Animals; Atropine; Carbachol; Desipramine; Dibenzocycloheptenes; Dimethylamines; Fema | 1972 |
Autonomic receptor mechanisms in embryonic chick myocardial cell cultures.
Topics: Acetylcholine; Animals; Carbachol; Chick Embryo; Culture Techniques; Heart; Isoproterenol; Muscle Co | 1971 |
Actions of bretylium tosylate at the neuromuscular junction.
Topics: Acetylcholine; Acetylcholinesterase; Animals; Bretylium Compounds; Carbachol; Diaphragm; Electrophys | 1971 |
[On the non-validity of the exponent furnished for the dose and for the constant of dissociation by the equation of mass applied to the contraction of a smooth muscle].
Topics: Animals; Carbachol; Guinea Pigs; Histamine; Intestines; Methacholine Compounds; Muscle Contraction; | 1971 |
The effect of 3,7-dimethyl-1-(5-oxo-hexyl)-xanthin on the -adrenergic receptors and on the activity of isoprenaline.
Topics: Aminophylline; Animals; Carbachol; Coronary Circulation; Drug Antagonism; Female; Guinea Pigs; Heart | 1971 |
An electrophysiological study of human foetal cardiac muscle.
Topics: Action Potentials; Carbachol; Electrophysiology; Fetal Heart; Gestational Age; Heart Atria; Humans; | 1971 |
Study of the contractile and electrophysiological maturation responses of the human foetal myocardium.
Topics: Abortion, Therapeutic; Action Potentials; Carbachol; Electrodes; Electrophysiology; Female; Fetal He | 1971 |
[On the relationship between membrane potential and potassium- or acetylcholine-contracture in the chronically denervated rat diaphragm].
Topics: Acetylcholine; Animals; Carbachol; Depression, Chemical; Diaphragm; In Vitro Techniques; Membrane Po | 1967 |
Motor responses of the urinary bladder and skeletal muscle in botulinum intoxicated rats.
Topics: Acetylcholine; Animals; Biological Assay; Botulism; Carbachol; Clostridium botulinum; Electric Stimu | 1967 |
Antioxytocic action of saponin isolated from Asparagus racemosus Willd (Shatavari) on uterine muscle.
Topics: Animals; Blood Pressure; Carbachol; Cats; Depression, Chemical; Female; Guinea Pigs; In Vitro Techni | 1969 |
Effects of potassium, acetylcholine, carbachol and histamine on Na22 movements in ileal smooth muscle.
Topics: Acetylcholine; Animals; Carbachol; Guinea Pigs; Histamine; Ileum; In Vitro Techniques; Muscle Contra | 1969 |
Acetylcholine-releasing effects of some nicotinic agents on chick biventer cervicis nerve muscle preparation.
Topics: Acetylcholine; Amino Alcohols; Animals; Carbachol; Chickens; Muscle Contraction; Muscles; Neuromuscu | 1969 |
The effects of some hemicholinium-like substances on the chick biventer cervicis muscle preparation.
Topics: Acetylcholine; Animals; Animals, Newborn; Bretylium Compounds; Carbachol; Chickens; Choline; Choline | 1969 |
The effect of reserpine on smooth muscle.
Topics: Acetylcholine; Animals; Barium; Carbachol; Colon; Estrus; Female; Guinea Pigs; Histamine; Ileum; Mus | 1969 |
The relationship between desensitization and the metaphilic effect at cholinergic receptors.
Topics: Animals; Anura; Carbachol; Chickens; Decamethonium Compounds; Desensitization, Immunologic; Muscle C | 1970 |
The rate of action of cholinergic drugs in guinea-pig isolated atria.
Topics: Acetylcholine; Animals; Carbachol; Guinea Pigs; Heart Atria; In Vitro Techniques; Kinetics; Muscle C | 1970 |
5,5-diphenyl-2-(2'-piperidinoethyl)-1,3-dioxolane-4-one a new drug with potent spasmolytic activity.
Topics: Acetylcholine; Animals; Asthma; Atropine; Barium; Blood Pressure; Blood Vessels; Carbachol; Cats; Ch | 1970 |
Pharmacologic identification of the lower esophageal sphincter.
Topics: Acetylcholine; Animals; Atropine; Barium; Carbachol; Esophagus; Female; Male; Manometry; Methacholin | 1970 |
[Anticholinergic effects depending on the chemical constitution of a series of tertiary and quaternary propylamine derivatives].
Topics: Animals; Atropine; Barium; Carbachol; Chemistry Techniques, Analytical; Chlorides; Guinea Pigs; Ileu | 1970 |
Development of autonomic neural responses in human heart.
Topics: Action Potentials; Carbachol; Fetal Heart; Gestational Age; Humans; In Vitro Techniques; Muscle Cont | 1971 |
Comparative responses of the isolated testicular capsule and parenchyma to autonomic drugs.
Topics: Acetylcholine; Animals; Autonomic Agents; Barium; Biological Transport; Carbachol; Cell Movement; Ep | 1971 |
Influence of pH on the action of parasympathomimetic drugs.
Topics: Animals; Carbachol; Electric Stimulation; Guinea Pigs; Heart; Heart Atria; Hydrogen-Ion Concentratio | 1967 |
[On the structure-effect-relations in cyclic acetylcholine analogues of the aminophenol-series].
Topics: Acetates; Amino Alcohols; Aniline Compounds; Animals; Butyrates; Carbachol; Chemistry, Pharmaceutica | 1967 |
Effects of some autonomic drugs on circular esophageal smooth muscle.
Topics: Acetylcholine; Animals; Atropine; Autonomic Agents; Carbachol; Cats; Electrophysiology; Epinephrine; | 1968 |
Is selective vagotomy selective?
Topics: Carbachol; Gallbladder; Humans; Muscle Contraction; Vagotomy | 1968 |
Effect of cholinergic and anticholingeric drugs on a new neuromuscular preparation of the chick.
Topics: Acetylcholine; Animals; Carbachol; Chickens; Decamethonium Compounds; Hexamethonium Compounds; In Vi | 1968 |
[Influence of hexobarbitol-Na and carbachol on frequency-induced and postextrasystolic potentiation in guinea pig isolated atria].
Topics: Animals; Biomechanical Phenomena; Carbachol; Depression, Chemical; Guinea Pigs; Heart; Heart Atria; | 1968 |
The effect of denervation on the sensitivity of the superior cervical ganglion of the pithed cat.
Topics: Acetylcholine; Animals; Carbachol; Carbamates; Cats; Denervation; Epinephrine; Ganglia, Autonomic; M | 1969 |
Subsensitivity of the rat ileum to cholinergic drugs.
Topics: Acetylcholine; Animals; Atropine; Carbachol; Cholinesterase Inhibitors; Female; Ileum; Methacholine | 1969 |
A comparative study of dopamine and noradrenaline on the rabbit aorta.
Topics: Animals; Aorta; Carbachol; Dopamine; Dopamine Antagonists; Drug Synergism; Female; Haloperidol; In V | 1969 |
Ionic interactions in acetylcholine contraction of the denervated rat diaphragm.
Topics: Acetylcholine; Animals; Calcium; Carbachol; Diaphragm; Lithium; Magnesium; Male; Manganese; Muscle C | 1969 |
Electrical membrane activity and frequency-force relations in normal, denervated and reserpine-pretreated cat heart muscle.
Topics: Action Potentials; Animals; Atropine; Carbachol; Cats; Denervation; Electric Stimulation; Electricit | 1969 |
Inhibition of the actions of carbachol and DFP on guinea pig isolated atria by alkane-bis-ammonium compounds.
Topics: Acetylcholine; Animals; Atropine; Carbachol; Chemical Phenomena; Chemistry; Guinea Pigs; Heart; Hear | 1969 |
Activation of contractile system in depolarized skeletal muscle fibers.
Topics: Animals; Anura; Barium; Calcium; Carbachol; Cell Membrane Permeability; Cobalt; Electrophysiology; I | 1969 |
Differences in the chronotropic and inotropic response of the rat atrium to choline esters, cholinesterase inhibitors and certain blocking agents.
Topics: Acetylcholine; Animals; Atropine; Carbachol; Choline; Curare; Drug Synergism; Electric Stimulation; | 1969 |
A new kind of drug antagonism: evidence that agonists cause a molecular change in acetylcholine receptors.
Topics: Acetylcholine; Animals; Caffeine; Carbachol; Chickens; Decamethonium Compounds; Drug Antagonism; Gal | 1969 |
Response of the isolated testicular capsule of the rat to autonomic drugs.
Topics: Acetylcholine; Animals; Autonomic Agents; Barium; Carbachol; Epinephrine; Histamine; In Vitro Techni | 1969 |
Effects of 2-PAM and TMB-4 on neuromuscular transmission.
Topics: Animals; Antineoplastic Agents; Anura; Carbachol; Cats; Cholinesterases; Decamethonium Compounds; El | 1965 |
The effect of temperature and frequency on the contractile force and inotropic response to ouabain, calcium and some other drugs of the hen isolated driven auricle.
Topics: Animals; Calcium; Carbachol; Digoxin; Heart; In Vitro Techniques; Muscle Contraction; Ouabain; Potas | 1965 |
The effects of succinylcholine, decamethonium, hexacarbacholine, gallamine and dimethyl tubocurarine on the twitch and tonic neuromuscular systems of the cat.
Topics: Animals; Carbachol; Cats; Decamethonium Compounds; Gallamine Triethiodide; In Vitro Techniques; Musc | 1966 |
The nicotinic effects of choline esters and of nicotine in guinea pig atria.
Topics: Acetylcholine; Animals; Atropine; Carbachol; Female; Guinea Pigs; Heart; Heart Atria; Hexamethonium | 1966 |
Mode of action of vasopressin on isolated proximal colon of the guinea-pig.
Topics: Acetylcholine; Animals; Calcium; Carbachol; Cocaine; Cold Temperature; Colon; Guinea Pigs; Hexametho | 1966 |