carbachol has been researched along with Melanoma in 5 studies
Carbachol: A slowly hydrolyzed CHOLINERGIC AGONIST that acts at both MUSCARINIC RECEPTORS and NICOTINIC RECEPTORS.
Melanoma: A malignant neoplasm derived from cells that are capable of forming melanin, which may occur in the skin of any part of the body, in the eye, or, rarely, in the mucous membranes of the genitalia, anus, oral cavity, or other sites. It occurs mostly in adults and may originate de novo or from a pigmented nevus or malignant lentigo. Melanomas frequently metastasize widely, and the regional lymph nodes, liver, lungs, and brain are likely to be involved. The incidence of malignant skin melanomas is rising rapidly in all parts of the world. (Stedman, 25th ed; from Rook et al., Textbook of Dermatology, 4th ed, p2445)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Regulations of intracellular protein kinase C (PKC) on carbachol (CCh)-induced intracellular calcium ([Ca(2+)]i) responses were investigated in different stages of melanoma cells." | 7.75 | Negative regulation of endogenous protein kinase Calpha on the dynamic change of carbachol-induced intracellular calcium response in different melanoma cells. ( Gao, TW; Liao, WJ; Lv, YJ; Wang, H; Wang, ZR; Yu, YQ; Zhang, YG, 2009) |
| "Regulations of intracellular protein kinase C (PKC) on carbachol (CCh)-induced intracellular calcium ([Ca(2+)]i) responses were investigated in different stages of melanoma cells." | 3.75 | Negative regulation of endogenous protein kinase Calpha on the dynamic change of carbachol-induced intracellular calcium response in different melanoma cells. ( Gao, TW; Liao, WJ; Lv, YJ; Wang, H; Wang, ZR; Yu, YQ; Zhang, YG, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 3 (60.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, H | 1 |
| Yu, YQ | 1 |
| Liao, WJ | 1 |
| Wang, ZR | 1 |
| Lv, YJ | 1 |
| Zhang, YG | 1 |
| Gao, TW | 1 |
| Nagy, D | 1 |
| Kosztka, L | 1 |
| Pap, P | 1 |
| Nagy, Z | 1 |
| Rusznák, Z | 1 |
| Csernoch, L | 1 |
| Szücs, G | 1 |
| Kohn, EC | 1 |
| Alessandro, R | 1 |
| Probst, J | 1 |
| Jacobs, W | 1 |
| Brilley, E | 1 |
| Felder, CC | 1 |
| Sailer, M | 1 |
| Oppitz, M | 1 |
| Drews, U | 1 |
| Leone, A | 1 |
| Mitsiades, N | 1 |
| Ward, Y | 1 |
| Spinelli, B | 1 |
| Poulaki, V | 1 |
| Tsokos, M | 1 |
| Kelly, K | 1 |
5 other studies available for carbachol and Melanoma
| Article | Year |
|---|---|
Negative regulation of endogenous protein kinase Calpha on the dynamic change of carbachol-induced intracellular calcium response in different melanoma cells.
Topics: Adolescent; Calcium Signaling; Carbachol; Cell Line, Tumor; Gene Expression Regulation, Neoplastic; | 2009 |
Cytoplasmic Ca2+ concentration changes evoked by muscarinic cholinergic stimulation in primary and metastatic melanoma cell lines.
Topics: Aniline Compounds; Atropine; Calcium; Carbachol; Cell Line, Tumor; Cytoplasm; Gene Expression Regula | 2011 |
Identification and molecular characterization of a m5 muscarinic receptor in A2058 human melanoma cells. Coupling to inhibition of adenylyl cyclase and stimulation of phospholipase A2.
Topics: Adenylyl Cyclase Inhibitors; Arachidonic Acid; Base Sequence; Blotting, Southern; Calcium; Carbachol | 1996 |
Induction of cellular contractions in the human melanoma cell line SK-mel 28 after muscarinic cholinergic stimulation.
Topics: Acetylcholine; Acetylcholinesterase; Atropine; Autocrine Communication; Carbachol; Cell Membrane; Ce | 2000 |
The Gem GTP-binding protein promotes morphological differentiation in neuroblastoma.
Topics: Animals; Carbachol; Cell Differentiation; Cholinergic Agonists; Ganglioneuroblastoma; Humans; Immedi | 2001 |