Page last updated: 2024-11-07

carbachol and Melanoma

carbachol has been researched along with Melanoma in 5 studies

Carbachol: A slowly hydrolyzed CHOLINERGIC AGONIST that acts at both MUSCARINIC RECEPTORS and NICOTINIC RECEPTORS.

Melanoma: A malignant neoplasm derived from cells that are capable of forming melanin, which may occur in the skin of any part of the body, in the eye, or, rarely, in the mucous membranes of the genitalia, anus, oral cavity, or other sites. It occurs mostly in adults and may originate de novo or from a pigmented nevus or malignant lentigo. Melanomas frequently metastasize widely, and the regional lymph nodes, liver, lungs, and brain are likely to be involved. The incidence of malignant skin melanomas is rising rapidly in all parts of the world. (Stedman, 25th ed; from Rook et al., Textbook of Dermatology, 4th ed, p2445)

Research Excerpts

ExcerptRelevanceReference
"Regulations of intracellular protein kinase C (PKC) on carbachol (CCh)-induced intracellular calcium ([Ca(2+)]i) responses were investigated in different stages of melanoma cells."7.75Negative regulation of endogenous protein kinase Calpha on the dynamic change of carbachol-induced intracellular calcium response in different melanoma cells. ( Gao, TW; Liao, WJ; Lv, YJ; Wang, H; Wang, ZR; Yu, YQ; Zhang, YG, 2009)
"Regulations of intracellular protein kinase C (PKC) on carbachol (CCh)-induced intracellular calcium ([Ca(2+)]i) responses were investigated in different stages of melanoma cells."3.75Negative regulation of endogenous protein kinase Calpha on the dynamic change of carbachol-induced intracellular calcium response in different melanoma cells. ( Gao, TW; Liao, WJ; Lv, YJ; Wang, H; Wang, ZR; Yu, YQ; Zhang, YG, 2009)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (20.00)18.2507
2000's3 (60.00)29.6817
2010's1 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Wang, H1
Yu, YQ1
Liao, WJ1
Wang, ZR1
Lv, YJ1
Zhang, YG1
Gao, TW1
Nagy, D1
Kosztka, L1
Pap, P1
Nagy, Z1
Rusznák, Z1
Csernoch, L1
Szücs, G1
Kohn, EC1
Alessandro, R1
Probst, J1
Jacobs, W1
Brilley, E1
Felder, CC1
Sailer, M1
Oppitz, M1
Drews, U1
Leone, A1
Mitsiades, N1
Ward, Y1
Spinelli, B1
Poulaki, V1
Tsokos, M1
Kelly, K1

Other Studies

5 other studies available for carbachol and Melanoma

ArticleYear
Negative regulation of endogenous protein kinase Calpha on the dynamic change of carbachol-induced intracellular calcium response in different melanoma cells.
    Journal of cellular physiology, 2009, Volume: 221, Issue:2

    Topics: Adolescent; Calcium Signaling; Carbachol; Cell Line, Tumor; Gene Expression Regulation, Neoplastic;

2009
Cytoplasmic Ca2+ concentration changes evoked by muscarinic cholinergic stimulation in primary and metastatic melanoma cell lines.
    Melanoma research, 2011, Volume: 21, Issue:1

    Topics: Aniline Compounds; Atropine; Calcium; Carbachol; Cell Line, Tumor; Cytoplasm; Gene Expression Regula

2011
Identification and molecular characterization of a m5 muscarinic receptor in A2058 human melanoma cells. Coupling to inhibition of adenylyl cyclase and stimulation of phospholipase A2.
    The Journal of biological chemistry, 1996, Jul-19, Volume: 271, Issue:29

    Topics: Adenylyl Cyclase Inhibitors; Arachidonic Acid; Base Sequence; Blotting, Southern; Calcium; Carbachol

1996
Induction of cellular contractions in the human melanoma cell line SK-mel 28 after muscarinic cholinergic stimulation.
    Anatomy and embryology, 2000, Volume: 201, Issue:1

    Topics: Acetylcholine; Acetylcholinesterase; Atropine; Autocrine Communication; Carbachol; Cell Membrane; Ce

2000
The Gem GTP-binding protein promotes morphological differentiation in neuroblastoma.
    Oncogene, 2001, May-31, Volume: 20, Issue:25

    Topics: Animals; Carbachol; Cell Differentiation; Cholinergic Agonists; Ganglioneuroblastoma; Humans; Immedi

2001