carbachol has been researched along with Long QT Syndrome in 3 studies
Carbachol: A slowly hydrolyzed CHOLINERGIC AGONIST that acts at both MUSCARINIC RECEPTORS and NICOTINIC RECEPTORS.
Long QT Syndrome: A condition that is characterized by episodes of fainting (SYNCOPE) and varying degree of ventricular arrhythmia as indicated by the prolonged QT interval. The inherited forms are caused by mutation of genes encoding cardiac ion channel proteins. The two major forms are ROMANO-WARD SYNDROME and JERVELL-LANGE NIELSEN SYNDROME.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Omadacycline is a first-in-class aminomethylcycline antibiotic with a broad spectrum of activity against Gram-positive and Gram-negative aerobes and anaerobes and atypical bacterial pathogens." | 1.43 | In Vitro and In Vivo Assessments of Cardiovascular Effects with Omadacycline. ( Tanaka, SK; Villano, S, 2016) |
| "Probucol is a cholesterol-lowering drug that could reduce hERG current by decreasing plasma membrane hERG protein expression and eventually cause long QT syndrome." | 1.42 | Mechanisms underlying probucol-induced hERG-channel deficiency. ( Geng, HZ; Li, BX; Liu, LR; Lv, L; Shi, YQ; Yan, CC; Yan, M; Zhang, X, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Shi, YQ | 1 |
| Yan, CC | 1 |
| Zhang, X | 1 |
| Yan, M | 1 |
| Liu, LR | 1 |
| Geng, HZ | 1 |
| Lv, L | 1 |
| Li, BX | 1 |
| Tanaka, SK | 1 |
| Villano, S | 1 |
| Fabritz, L | 1 |
| Damke, D | 1 |
| Emmerich, M | 1 |
| Kaufmann, SG | 1 |
| Theis, K | 1 |
| Blana, A | 1 |
| Fortmüller, L | 1 |
| Laakmann, S | 1 |
| Hermann, S | 1 |
| Aleynichenko, E | 1 |
| Steinfurt, J | 1 |
| Volkery, D | 1 |
| Riemann, B | 1 |
| Kirchhefer, U | 1 |
| Franz, MR | 1 |
| Breithardt, G | 1 |
| Carmeliet, E | 1 |
| Schäfers, M | 1 |
| Maier, SK | 1 |
| Carmeliet, P | 1 |
| Kirchhof, P | 1 |
3 other studies available for carbachol and Long QT Syndrome
| Article | Year |
|---|---|
Mechanisms underlying probucol-induced hERG-channel deficiency.
Topics: Anticholesteremic Agents; Carbachol; Dose-Response Relationship, Drug; Endosomal Sorting Complexes R | 2015 |
In Vitro and In Vivo Assessments of Cardiovascular Effects with Omadacycline.
Topics: Animals; Anti-Bacterial Agents; Calcium Channels, L-Type; Carbachol; Cholinergic Agonists; ERG1 Pota | 2016 |
Autonomic modulation and antiarrhythmic therapy in a model of long QT syndrome type 3.
Topics: Action Potentials; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Anti-Arrhythmia A | 2010 |