carbachol has been researched along with Ischemia in 25 studies
Carbachol: A slowly hydrolyzed CHOLINERGIC AGONIST that acts at both MUSCARINIC RECEPTORS and NICOTINIC RECEPTORS.
Ischemia: A hypoperfusion of the BLOOD through an organ or tissue caused by a PATHOLOGIC CONSTRICTION or obstruction of its BLOOD VESSELS, or an absence of BLOOD CIRCULATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To investigate the effect of carbachol (CAR) on visceral perfusion and lipid oxidation injury in rats with sepsis." | 7.75 | [The protective effects of carbachol on visceral ischemia-induced lipid peroxidation injury in rats with sepsis]. ( Bai, HY; Bao, CM; Hu, S; Zhang, LJ, 2009) |
| "To determine the efficacy of coenzyme Q10 (CoQ10) and alpha-lipoic acid (alpha-LA), either alone or in combination, to protect the contractile responses of the rabbit urinary bladder from damage caused by repetitive stimulation in the presence or absence of in vitro ischemia." | 7.74 | Effect of co-enzyme Q10 and alpha-lipoic acid on response of rabbit urinary bladder to repetitive stimulation and in vitro ischemia. ( Levin, RM; Lin, WY; Rehfuss, A; Schuler, C, 2008) |
| "To investigate the effects of carbachol on the levels of tumor necrosis factor-alpha (TNF-alpha), interleukin-10 (IL-10) and cortisol in plasma of rats during gut ischemia-reperfusion." | 7.72 | [Effects of carbachol on plasma levels of tumor necrosis factor-alpha and interleukin-10 in rats during gut ischemia-reperfusion]. ( Han, CH; Hu, S; Jiang, XG; Jin, H; Lü, Y; Sheng, ZY; Shi, DG; Sun, D, 2003) |
| "To investigate the effects of carbachol on local inflammation in gut tissue during ischemia/reperfusion (I/R)." | 7.72 | [Carbachol alleviates inflammation in gut tissue during ischemia/reperfusion in rats]. ( Hu, S; Jiang, XG; Li, JY; Lu, Y; Sheng, ZY; Shi, DG; Sun, D, 2003) |
| "To investigate the effects of carbachol injection in intestine on plasma levels of tumor necrosis factor-alpha(TNF-alpha), interleukin-10 (IL-10) and cortisol in rats during gut ischemia/reperfusion." | 7.72 | [Effects of carbachol injection in intestine on plasma levels of inflammatory medium in rats during gut ischemia/reperfusion]. ( Hu, S; Jiang, XG; Li, JY; Lu, Y; Sheng, ZY; Shi, DG; Sun, D, 2004) |
| "To investigate the effect of carbachol (CAR) on visceral perfusion and lipid oxidation injury in rats with sepsis." | 3.75 | [The protective effects of carbachol on visceral ischemia-induced lipid peroxidation injury in rats with sepsis]. ( Bai, HY; Bao, CM; Hu, S; Zhang, LJ, 2009) |
| "To determine the efficacy of coenzyme Q10 (CoQ10) and alpha-lipoic acid (alpha-LA), either alone or in combination, to protect the contractile responses of the rabbit urinary bladder from damage caused by repetitive stimulation in the presence or absence of in vitro ischemia." | 3.74 | Effect of co-enzyme Q10 and alpha-lipoic acid on response of rabbit urinary bladder to repetitive stimulation and in vitro ischemia. ( Levin, RM; Lin, WY; Rehfuss, A; Schuler, C, 2008) |
| "The maximal responses to FS, carbachol and adenosine triphosphate (ATP) were not decreased by 4-hour ischemia alone, whereas the response to KCl was decreased significantly." | 3.72 | Reperfusion injury of the rat bladder is worse than ischemia. ( Aslan, AR; Bratslavsky, G; Kogan, BA; Levin, RM; Matsumoto, S, 2003) |
| "To investigate the effects of carbachol on local inflammation in gut tissue during ischemia/reperfusion (I/R)." | 3.72 | [Carbachol alleviates inflammation in gut tissue during ischemia/reperfusion in rats]. ( Hu, S; Jiang, XG; Li, JY; Lu, Y; Sheng, ZY; Shi, DG; Sun, D, 2003) |
| "To investigate the effects of carbachol injection in intestine on plasma levels of tumor necrosis factor-alpha(TNF-alpha), interleukin-10 (IL-10) and cortisol in rats during gut ischemia/reperfusion." | 3.72 | [Effects of carbachol injection in intestine on plasma levels of inflammatory medium in rats during gut ischemia/reperfusion]. ( Hu, S; Jiang, XG; Li, JY; Lu, Y; Sheng, ZY; Shi, DG; Sun, D, 2004) |
| "The results showed that Kohki Tea pretreatment protected the bladder's response to FS from the detrimental effects of repetitive stimulation and the detrimental effects of both in vitro ischemia and repetitive stimulation on the contractile responses to carbachol and KCl." | 3.72 | Oral Kohki Tea and its protective effect against in vitro ischemic damage to the bladder. ( Aikawa, K; Kambara, T; Leggett, RE; Levin, RM; Murakami, T; Whitbeck, C, 2004) |
| "Effects of 1-hour in vitro ischemia on rabbit corporal tissue were as follows: (1) an 85% decrease in contractile response to phenylephrine, and (2) a marked increase in rate of contractile response to phenylephrine." | 3.70 | Digital analysis of the pharmacological effects of in vitro ischemia on rabbit corpus cavernosum. ( Horan, P; Levin, RM; Liu, SP, 1998) |
| "The effects of repetitive and nonrepetitive FS on the contractile responses of isolated strips of rabbit bladder to FS, carbachol, and KCl were determined in the presence of 3 different incubation media: O2 + glucose (normal physiological medium); N2 + glucose (in vitro hypoxia), and N2 - glucose (in vitro ischemia)." | 3.70 | Effect of repetitive stimulation on the contractile response of rabbit urinary bladder subjected to in vitro hypoxia or in vitro ischemia followed by reoxygenation. ( Horan, P; Levin, RM; Liu, SP; Ohnishi, N, 1998) |
| "To investigate the effect of anoxia/glucopenia and re-superfusion on intrinsic nerves in the mammalian urinary bladder." | 1.33 | Effect of anoxia-glucopenia and re-superfusion on intrinsic nerves of mammalian detrusor smooth muscle: importance of glucose metabolism. ( Gerli, R; Maestrini, D; Pessina, F; Sgaragli, G; Solito, R, 2005) |
| " (c) Ethanol mediated a dose-response enhancement of the contractile dysfunctions caused by in vitro ischemia." | 1.33 | Effect of ethanol on the response of the rat urinary bladder to in vitro ischemia: protective effect of alpha-lipoic acid. ( Danek, M; Haugaard, N; Levin, RM; Whitbeck, C, 2005) |
| "To study the effects of anoxia and substrate depletion, both separately and combined, on the contractile responses of guinea-pig detrusor smooth muscle strips to activation of intrinsic nerves, application of agonists and depolarization with high potassium solution." | 1.30 | The effect of anoxia and glucose-free solutions on the contractile response of guinea-pig detrusor strips to intrinsic nerve stimulation and the application of excitatory agonists. ( Brading, AF; McMurray, G; Pessina, F; Wiggin, A, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (4.00) | 18.7374 |
| 1990's | 9 (36.00) | 18.2507 |
| 2000's | 14 (56.00) | 29.6817 |
| 2010's | 1 (4.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hu, S | 4 |
| Zhang, LJ | 1 |
| Bai, HY | 1 |
| Bao, CM | 1 |
| Valeri, A | 1 |
| Capasso, R | 1 |
| Valoti, M | 1 |
| Pessina, F | 3 |
| Jiang, XG | 3 |
| Shi, DG | 3 |
| Jin, H | 1 |
| Lü, Y | 3 |
| Han, CH | 1 |
| Sun, D | 3 |
| Sheng, ZY | 3 |
| Bratslavsky, G | 2 |
| Kogan, BA | 2 |
| Matsumoto, S | 1 |
| Aslan, AR | 1 |
| Levin, RM | 11 |
| Lorenzi, B | 1 |
| McMurray, G | 2 |
| Jarvis, G | 1 |
| Brading, AF | 2 |
| Li, JY | 2 |
| Azadzoi, KM | 1 |
| Heim, VK | 1 |
| Tarcan, T | 1 |
| Siroky, MB | 1 |
| Leggett, RE | 2 |
| Whitbeck, C | 6 |
| Murakami, T | 1 |
| Kambara, T | 1 |
| Aikawa, K | 1 |
| Solito, R | 1 |
| Maestrini, D | 1 |
| Gerli, R | 1 |
| Sgaragli, G | 1 |
| Danek, M | 1 |
| Haugaard, N | 1 |
| Lin, WY | 1 |
| Rehfuss, A | 1 |
| Schuler, C | 2 |
| Juan, YS | 1 |
| Li, S | 1 |
| Huang, CH | 1 |
| Mannikarottu, A | 1 |
| Hersey, K | 1 |
| Hu, ZY | 1 |
| Zhang, JP | 1 |
| Rhodes, PG | 1 |
| Sun, GY | 1 |
| Loke, KE | 1 |
| Woodman, OL | 1 |
| Wiggin, A | 1 |
| Liu, SP | 2 |
| Horan, P | 5 |
| Ohnishi, N | 1 |
| Leggett, R | 3 |
| English, M | 1 |
| Barretto, M | 1 |
| Dubuc, M | 1 |
| O'Connor, L | 1 |
| Masuda, H | 1 |
| Tsujii, T | 1 |
| Okuno, T | 1 |
| Kihara, K | 1 |
| Goto, M | 1 |
| Azuma, H | 1 |
| Olack, B | 1 |
| Hill, A | 1 |
| Scharp, D | 1 |
| Lacy, P | 1 |
| Smith, B | 1 |
| Butler, M | 1 |
25 other studies available for carbachol and Ischemia
| Article | Year |
|---|---|
[The protective effects of carbachol on visceral ischemia-induced lipid peroxidation injury in rats with sepsis].
Topics: Animals; Carbachol; Disease Models, Animal; Hemodynamics; Ischemia; Lipid Peroxidation; Male; Random | 2009 |
Effects of St John's wort and its active constituents, hypericin and hyperforin, on isolated rat urinary bladder.
Topics: Animals; Anthracenes; Carbachol; Cell Membrane; Dose-Response Relationship, Drug; Electric Stimulati | 2012 |
[Effects of carbachol on plasma levels of tumor necrosis factor-alpha and interleukin-10 in rats during gut ischemia-reperfusion].
Topics: Animals; Carbachol; Cholinergic Agonists; Hydrocortisone; Interleukin-10; Intestines; Ischemia; Rats | 2003 |
Reperfusion injury of the rat bladder is worse than ischemia.
Topics: Adaptation, Physiological; Adenosine Triphosphate; Animals; Carbachol; Culture Techniques; Electric | 2003 |
Preconditioning protects the guinea-pig urinary bladder against ischaemic conditions in vitro.
Topics: Animals; Carbachol; Electric Stimulation; Female; Guinea Pigs; In Vitro Techniques; Inositol 1,4,5-T | 2003 |
[Carbachol alleviates inflammation in gut tissue during ischemia/reperfusion in rats].
Topics: Animals; Carbachol; Gastroenteritis; Intestines; Ischemia; Peroxidase; Rats; Rats, Wistar; Reperfusi | 2003 |
[Effects of carbachol injection in intestine on plasma levels of inflammatory medium in rats during gut ischemia/reperfusion].
Topics: Animals; Carbachol; Cardiotonic Agents; Hydrocortisone; Injections; Interleukin-10; Intestines; Isch | 2004 |
Alteration of urothelial-mediated tone in the ischemic bladder: role of eicosanoids.
Topics: Animals; Arachidonate 5-Lipoxygenase; Blood Pressure; Carbachol; Eicosanoids; Electric Stimulation; | 2004 |
Oral Kohki Tea and its protective effect against in vitro ischemic damage to the bladder.
Topics: Administration, Oral; Animals; Carbachol; Electric Stimulation; Hypoxia; Ischemia; Male; Muscle Cont | 2004 |
Effect of anoxia-glucopenia and re-superfusion on intrinsic nerves of mammalian detrusor smooth muscle: importance of glucose metabolism.
Topics: Anaerobiosis; Animals; Antimetabolites; Carbachol; Cebus; Deoxyglucose; Electric Stimulation; Gangli | 2005 |
Effect of ethanol on the response of the rat urinary bladder to in vitro ischemia: protective effect of alpha-lipoic acid.
Topics: Animals; Carbachol; Ethanol; In Vitro Techniques; Ischemia; Male; Muscle Contraction; Protective Age | 2005 |
Effect of co-enzyme Q10 and alpha-lipoic acid on response of rabbit urinary bladder to repetitive stimulation and in vitro ischemia.
Topics: Animals; Antioxidants; Carbachol; Electric Stimulation; Electron Transport Chain Complex Proteins; I | 2008 |
The effect of ischemia/reperfusion on rabbit bladder--role of Rho-kinase and smooth muscle regulatory proteins.
Topics: Animals; Blotting, Western; Calmodulin-Binding Proteins; Carbachol; Contractile Proteins; Disease Mo | 2009 |
In utero hypoxic ischemia decreases the cholinergic agonist-stimulated poly-phosphoinositide turnover in the developing rat brain.
Topics: Animals; Brain; Carbachol; Constriction; Female; Hypoxia; Inositol; Ischemia; Lithium Chloride; Para | 1995 |
Effect of ischaemic preconditioning on vascular dysfunction induced by ischaemia and reperfusion in rat hindquarters.
Topics: Acetylcholine; Animals; Carbachol; Electric Stimulation; Female; Hindlimb; Ischemia; Ischemic Precon | 1996 |
The effect of anoxia and glucose-free solutions on the contractile response of guinea-pig detrusor strips to intrinsic nerve stimulation and the application of excitatory agonists.
Topics: Adenosine Triphosphate; Animals; Carbachol; Dose-Response Relationship, Drug; Electric Stimulation; | 1997 |
Digital analysis of the pharmacological effects of in vitro ischemia on rabbit corpus cavernosum.
Topics: Animals; Carbachol; Computer Simulation; Ischemia; Male; Muscarinic Agonists; Muscle Contraction; Mu | 1998 |
Effect of repetitive stimulation on the contractile response of rabbit urinary bladder subjected to in vitro hypoxia or in vitro ischemia followed by reoxygenation.
Topics: Animals; Carbachol; Cell Hypoxia; Disease Models, Animal; Electric Stimulation; Glucose; In Vitro Te | 1998 |
Effect of calcium and calcium chelator on the response of the bladder to in vitro ischaemia.
Topics: Animals; Calcium; Carbachol; Chelating Agents; Dose-Response Relationship, Drug; Egtazic Acid; Free | 1998 |
Correlation of EGTA and calcium-blocking agents on the response of the bladder to in vitro ischemia.
Topics: Animals; Calcium Channel Blockers; Carbachol; Chelating Agents; Diltiazem; Egtazic Acid; Electric St | 1999 |
Effects of in vivo ischemia on contractile responses of rabbit bladder to field stimulation, carbachol, ATP and KCl.
Topics: Adenosine Triphosphate; Animals; Carbachol; Electric Stimulation; Ischemia; Male; Muscle Contraction | 1999 |
Normal detrusor is more sensitive than hypertrophied detrusor to in vitro ischemia followed by re-oxygenation.
Topics: Animals; Carbachol; Electric Stimulation; Hypertrophy; Ischemia; Male; Muscle Contraction; Muscle, S | 2000 |
Accumulated endogenous NOS inhibitors, decreased NOS activity, and impaired cavernosal relaxation with ischemia.
Topics: Animals; Arginine; Calcium; Carbachol; Cholinergic Agonists; Cyclic GMP; Disease Models, Animal; Dos | 2002 |
Automated purification of canine islets.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Blood Glucose; Carbachol; Cell Separation; Cell Survival; Cent | 1992 |
The autonomic control of colonic mucin secretion in the mouse.
Topics: Administration, Oral; Animals; Atropine; Autonomic Nervous System; Carbachol; Colitis; Colon; Epithe | 1974 |