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carbachol and Insulin Sensitivity

carbachol has been researched along with Insulin Sensitivity in 11 studies

Carbachol: A slowly hydrolyzed CHOLINERGIC AGONIST that acts at both MUSCARINIC RECEPTORS and NICOTINIC RECEPTORS.

Research Excerpts

ExcerptRelevanceReference
" Metformin treatment improved the insulin sensitivity, and normalized the in vitro bladder hypercontractility and cystometric dysfunction in obese mice."3.78Role of PKC and CaV1.2 in detrusor overactivity in a model of obesity associated with insulin resistance in mice. ( Anhê, GF; Antunes, E; Calixto, MC; De Nucci, G; Grant, AD; Leiria, LO; Lintomen, L; Mónica, FZ; Sollon, C; Zanesco, A, 2012)
"Insulin secretion in response to acetylcholine receptor activation by carbachol in insulin resistance induced by 12 weeks of high-fat diet in C57BL/6J mice is exaggerated."3.70Potentiated beta-cell response to non-glucose stimuli in insulin-resistant C57BL/6J mice. ( Ahrén, B; Simonsson, E, 1998)
"Insulin resistance is followed by an islet adaptation resulting in a compensating increase in insulin secretion and hyperinsulinemia."1.31Islet phospholipase A(2) activation is potentiated in insulin resistant mice. ( Ahrén, B; Karlsson, S; Simonsson, E, 2000)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (18.18)18.2507
2000's3 (27.27)29.6817
2010's6 (54.55)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Yamamoto, J1
Imai, J1
Izumi, T1
Takahashi, H1
Kawana, Y1
Takahashi, K1
Kodama, S1
Kaneko, K1
Gao, J1
Uno, K1
Sawada, S1
Asano, T1
Kalinichenko, VV1
Susaki, EA1
Kanzaki, M1
Ueda, HR1
Ishigaki, Y1
Yamada, T1
Katagiri, H1
Lubaczeuski, C2
Balbo, SL2
Ribeiro, RA2
Vettorazzi, JF1
Santos-Silva, JC1
Carneiro, EM2
Bonfleur, ML2
Tallapragada, DS1
Karpe, PA1
Tikoo, K1
Mendes, MC1
Maller, AC1
Angelini, N1
Rafacho, A1
Boschero, AC1
Bosqueiro, JR1
Leiria, LO1
Sollon, C1
Calixto, MC1
Lintomen, L1
Mónica, FZ1
Anhê, GF1
De Nucci, G1
Zanesco, A1
Grant, AD1
Antunes, E1
Ahrén, B3
Simonsson, E3
Scheurink, AJ1
Mulder, H1
Myrsén, U1
Sundler, F1
Karlsson, S1
Zawalich, WS1
Zawalich, KC1
Guerre-Millo, M1
Rouault, C1
Poulain, P1
André, J1
Poitout, V1
Peters, JM1
Gonzalez, FJ1
Fruchart, JC1
Reach, G1
Staels, B1

Other Studies

11 other studies available for carbachol and Insulin Sensitivity

ArticleYear
Neuronal signals regulate obesity induced β-cell proliferation by FoxM1 dependent mechanism.
    Nature communications, 2017, 12-05, Volume: 8, Issue:1

    Topics: Animals; Blood Glucose; Brain; Carbachol; Cell Proliferation; Cholinergic Agonists; Forkhead Box Pro

2017
Vagotomy ameliorates islet morphofunction and body metabolic homeostasis in MSG-obese rats.
    Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 2015, Volume: 48, Issue:5

    Topics: Animals; Carbachol; Cell Count; Cholesterol; Cholinergic Agonists; Flavoring Agents; Glucose; Homeos

2015
Long-lasting partnership between insulin resistance and endothelial dysfunction: role of metabolic memory.
    British journal of pharmacology, 2015, Volume: 172, Issue:16

    Topics: Animals; Blood Glucose; Body Weight; Carbachol; Diet, High-Fat; Endothelium, Vascular; Insulin; Insu

2015
Vagotomy diminishes obesity in cafeteria rats by decreasing cholinergic potentiation of insulin release.
    Journal of physiology and biochemistry, 2016, Volume: 72, Issue:4

    Topics: 1-Methyl-3-isobutylxanthine; Adipose Tissue; Animals; Body Weight; Carbachol; Colforsin; Cyclic AMP;

2016
Involvement of the cholinergic pathway in glucocorticoid-induced hyperinsulinemia in rats.
    Diabetes research and clinical practice, 2010, Volume: 87, Issue:2

    Topics: Animals; Blood Glucose; Carbachol; Dexamethasone; Drug Tolerance; Glucocorticoids; Glucose; Humans;

2010
Role of PKC and CaV1.2 in detrusor overactivity in a model of obesity associated with insulin resistance in mice.
    PloS one, 2012, Volume: 7, Issue:11

    Topics: Adiposity; Amlodipine; Animals; Body Weight; Calcium Channel Blockers; Calcium Channels, L-Type; Cal

2012
Dissociated insulinotropic sensitivity to glucose and carbachol in high-fat diet-induced insulin resistance in C57BL/6J mice.
    Metabolism: clinical and experimental, 1997, Volume: 46, Issue:1

    Topics: Animals; Blood Glucose; Body Weight; Carbachol; Cholesterol; Dietary Fats; Eating; Fatty Acids, None

1997
Potentiated beta-cell response to non-glucose stimuli in insulin-resistant C57BL/6J mice.
    European journal of pharmacology, 1998, Jun-05, Volume: 350, Issue:2-3

    Topics: Animals; Antimetabolites; Blood Glucose; Body Weight; Carbachol; Deoxyglucose; Diet; Female; Glucago

1998
Islet phospholipase A(2) activation is potentiated in insulin resistant mice.
    Biochemical and biophysical research communications, 2000, Jun-07, Volume: 272, Issue:2

    Topics: Animals; Arachidonic Acid; Blood Glucose; Body Weight; Carbachol; Diabetes Mellitus, Type 2; Dietary

2000
A link between insulin resistance and hyperinsulinemia: inhibitors of phosphatidylinositol 3-kinase augment glucose-induced insulin secretion from islets of lean, but not obese, rats.
    Endocrinology, 2000, Volume: 141, Issue:9

    Topics: Androstadienes; Animals; Calcium; Carbachol; Cell Separation; Enzyme Inhibitors; Glucose; Hyperinsul

2000
PPAR-alpha-null mice are protected from high-fat diet-induced insulin resistance.
    Diabetes, 2001, Volume: 50, Issue:12

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Blood Glucose; Carbachol; Dietary Fats; Drug Synergism; Fastin

2001