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carbachol and Hypertension, Pulmonary

carbachol has been researched along with Hypertension, Pulmonary in 7 studies

Carbachol: A slowly hydrolyzed CHOLINERGIC AGONIST that acts at both MUSCARINIC RECEPTORS and NICOTINIC RECEPTORS.

Hypertension, Pulmonary: Increased VASCULAR RESISTANCE in the PULMONARY CIRCULATION, usually secondary to HEART DISEASES or LUNG DISEASES.

Research Excerpts

ExcerptRelevanceReference
"In the pulmonary artery isolated from 1-week hypoxia-induced pulmonary hypertensive rats, endothelial NO production stimulated by carbachol was decreased significantly in in situ visualization using diaminofluorescein-2 diacetate and also in cGMP content."3.71Decreased endothelial nitric-oxide synthase (eNOS) activity resulting from abnormal interaction between eNOS and its regulatory proteins in hypoxia-induced pulmonary hypertension. ( Hori, M; Karaki, H; Murata, T; Ozaki, H; Sato, K, 2002)
"Right ventricular hypertrophy was increased by 51%, 93% and 55%, respectively, at 14 days."1.31Differences in time-related cardiopulmonary responses to hypoxia in three rat strains. ( Bochnowicz, S; Hart, T; Hay, DW; Louden, C; Luttmann, MA; Osborn, RR; Underwood, DC, 2000)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19901 (14.29)18.7374
1990's2 (28.57)18.2507
2000's4 (57.14)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gurney, AM1
Howarth, FC1
Murata, T1
Sato, K1
Hori, M2
Ozaki, H2
Karaki, H2
Matsukura, Y1
Washizu, M1
Kondo, M1
Motoyoshi, S1
Itoh, A1
Nakajyo, S1
Shimizu, K1
Urakawa, N1
Nakazawa, H1
Bochnowicz, S1
Osborn, RR1
Luttmann, MA1
Louden, C1
Hart, T1
Hay, DW1
Underwood, DC1
Karamsetty, MR1
Klinger, JR1
Hill, NS1
Both, A1

Other Studies

7 other studies available for carbachol and Hypertension, Pulmonary

ArticleYear
Effects of streptozotocin-induced diabetes on the pharmacology of rat conduit and resistance intrapulmonary arteries.
    Cardiovascular diabetology, 2009, Jan-21, Volume: 8

    Topics: Animals; Calcium Signaling; Carbachol; Diabetes Mellitus, Experimental; Diabetic Angiopathies; Dinop

2009
Decreased endothelial nitric-oxide synthase (eNOS) activity resulting from abnormal interaction between eNOS and its regulatory proteins in hypoxia-induced pulmonary hypertension.
    The Journal of biological chemistry, 2002, Nov-15, Volume: 277, Issue:46

    Topics: Animals; Blotting, Western; Body Weight; Calcium; Carbachol; Cell Membrane; Cyclic GMP; Electrophore

2002
Decreased pulmonary arterial endothelium-dependent relaxation in heartworm-infected dogs with pulmonary hypertension.
    American journal of veterinary research, 1997, Volume: 58, Issue:2

    Topics: Animals; Blood Pressure; Carbachol; Dirofilariasis; Dog Diseases; Dogs; Endothelium, Vascular; Femal

1997
Mechanisms underlying the impairment of endothelium-dependent relaxation in the pulmonary artery of monocrotaline-induced pulmonary hypertensive rats.
    British journal of pharmacology, 1999, Volume: 128, Issue:5

    Topics: Animals; Body Weight; Calcium; Carbachol; Cyclic GMP; Endothelium, Vascular; Hypertension, Pulmonary

1999
Differences in time-related cardiopulmonary responses to hypoxia in three rat strains.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 2000, Volume: 22, Issue:5

    Topics: Altitude; Animals; Carbachol; Disease Models, Animal; Endothelin-1; Endothelins; Hypertension, Pulmo

2000
Phytoestrogens restore nitric oxide-mediated relaxation in isolated pulmonary arteries from chronically hypoxic rats.
    The Journal of pharmacology and experimental therapeutics, 2001, Volume: 297, Issue:3

    Topics: Animals; Carbachol; Cholinergic Agonists; Chronic Disease; Dose-Response Relationship, Drug; Estradi

2001
[Therapy of primary pulmonary hypertension].
    Zeitschrift fur Kreislaufforschung, 1970, Volume: 59, Issue:10

    Topics: Acetylcholine; Amino Alcohols; Carbachol; Child; Diazepam; Diazoxide; Female; Humans; Hypertension,

1970