carbachol has been researched along with Hypersensitivity in 16 studies
Carbachol: A slowly hydrolyzed CHOLINERGIC AGONIST that acts at both MUSCARINIC RECEPTORS and NICOTINIC RECEPTORS.
Hypersensitivity: Altered reactivity to an antigen, which can result in pathologic reactions upon subsequent exposure to that particular antigen.
| Excerpt | Relevance | Reference |
|---|---|---|
| " L-Serine borate (45 mM), an inhibitor of gamma-glutamyl transpeptidase, shifted the dose-response curve of LTC4 to the left by 161-fold, and L-cysteine (6 mM), an inhibitor of aminopeptidase, shifted the dose-response curves of LTC4 and LTD4 to the left by 67- and 23-fold, respectively." | 1.28 | Characterization of sulfidopeptide leukotriene responses in sheep tracheal smooth muscle in vitro. ( Abraham, WM; Jackowski, JT; Tomioka, K, 1991) |
| "9-fold leftward shift in dose-response curves to aerosolized carbachol (p less than 0." | 1.28 | Airway effects of inhaled bradykinin, substance P, and neurokinin A in sheep. ( Abraham, WM; Ahmed, A; Baugh, LE; Cortes, A; Farmer, SG; Harbeson, SL; Soler, M, 1991) |
| " Nevertheless, AHR was apparent in both trials as indicated by a mean twofold leftward shift in the dose-response curves to inhaled carbachol (P less than 0." | 1.28 | Separation of late bronchial responses from airway hyperresponsiveness in allergic sheep. ( Abraham, WM; Sielczak, M; Solér, M, 1991) |
| "Sch 37224 treatment reduced the peak immediate and peak late increases in SRL to 128 +/- 32 and 43 +/- 17%, respectively (both P less than ." | 1.27 | A leukotriene and thromboxane inhibitor (Sch 37224) blocks antigen-induced immediate and late responses and airway hyperresponsiveness in allergic sheep. ( Abraham, WM; Garrido, R; Stevenson, JS, 1988) |
| " Mechanical responses of sensitized TSM were characterized by hyperreactivity (upward shift of the dose-response relationship) to acetylcholine (ACh), atropine-sensitive spontaneous base line activity and prolonged isometric force plateaus." | 1.27 | Local parasympathetic mechanisms for ragweed-sensitized canine trachealis hyperresponsiveness. ( Kepron, W; Kroeger, EA; Mitchell, RW; Stephens, NL, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (43.75) | 18.7374 |
| 1990's | 6 (37.50) | 18.2507 |
| 2000's | 3 (18.75) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Teplov, AY | 1 |
| Grishin, SN | 1 |
| Mukhamedyarov, MA | 1 |
| Ziganshin, AU | 1 |
| Zefirov, AL | 1 |
| Palotás, A | 1 |
| LASAREWA, DN | 1 |
| Schmutzler, W | 1 |
| Glück, S | 1 |
| Huber, M | 1 |
| Fischer, B | 1 |
| Pult, P | 1 |
| Smith, LJ | 1 |
| Shelhamer, JH | 1 |
| Kaliner, M | 1 |
| Lewis, CA | 1 |
| Raeburn, D | 1 |
| Broadley, KJ | 1 |
| Brusselle, G | 1 |
| Kips, J | 1 |
| Joos, G | 1 |
| Bluethmann, H | 1 |
| Pauwels, R | 1 |
| Menciu, C | 1 |
| Duflos, M | 1 |
| Fouchard, F | 1 |
| Le Baut, G | 1 |
| Emig, P | 1 |
| Achterrath, U | 1 |
| Szelenyi, I | 1 |
| Nickel, B | 1 |
| Schmidt, J | 1 |
| Kutscher, B | 1 |
| Günther, E | 1 |
| Ahmed, T | 1 |
| Ungo, J | 1 |
| Zhou, M | 1 |
| Campo, C | 1 |
| Strömberg, T | 1 |
| Adams, J | 1 |
| Abraham, W | 1 |
| Sackner, M | 1 |
| Krell, RD | 1 |
| Tomioka, K | 1 |
| Jackowski, JT | 1 |
| Abraham, WM | 4 |
| Ahmed, A | 1 |
| Cortes, A | 1 |
| Soler, M | 2 |
| Farmer, SG | 1 |
| Baugh, LE | 1 |
| Harbeson, SL | 1 |
| Sielczak, M | 1 |
| Loesberg, C | 1 |
| Woutersen-van Nijnanten, FM | 1 |
| Nijkamp, FP | 1 |
| Stevenson, JS | 1 |
| Garrido, R | 1 |
| Mitchell, RW | 1 |
| Kroeger, EA | 1 |
| Kepron, W | 1 |
| Stephens, NL | 1 |
16 other studies available for carbachol and Hypersensitivity
| Article | Year |
|---|---|
Ovalbumin-induced sensitization affects non-quantal acetylcholine release from motor nerve terminals and alters contractility of skeletal muscles in mice.
Topics: Acetylcholine; Animals; Carbachol; Cholinergic Agonists; Disease Models, Animal; Electrophysiology; | 2009 |
[Reaction of the cardiovascular system of the sensitized dog and rabbit to adrenaline and carbocholine].
Topics: Animals; Carbachol; Cardiovascular System; Dogs; Epinephrine; Hypersensitivity; Immune System Diseas | 1960 |
Is cholinergic histamine release a mechanism of allergy or pseudo-allergy?
Topics: Acetylcholine; Animals; Carbachol; Guinea Pigs; Histamine Release; Humans; Hypersensitivity; Intrade | 1983 |
Cholinergic nervous system and immediate hypersensitivity. II. An analysis of pupillary responses.
Topics: Adolescent; Adult; Aged; Asthma; Carbachol; Female; Humans; Hypersensitivity; Hypersensitivity, Imme | 1980 |
Non-specific airway hyperreactivity in isolated respiratory preparations from guinea-pigs sensitized and challenged with ovalbumin.
Topics: Adenosine; Animals; Carbachol; Dose-Response Relationship, Drug; Guinea Pigs; Histamine; Hypersensit | 1994 |
Allergen-induced airway inflammation and bronchial responsiveness in wild-type and interleukin-4-deficient mice.
Topics: Allergens; Animals; Asthma; Bronchial Provocation Tests; Carbachol; Hypersensitivity; Immunoglobulin | 1995 |
New N-(pyridin-4-yl)-(indol-3-yl)acetamides and propanamides as antiallergic agents.
Topics: Acetylcholine; Animals; Anti-Allergic Agents; Bronchoalveolar Lavage; Capillary Permeability; Carbac | 1999 |
Inhibition of allergic late airway responses by inhaled heparin-derived oligosaccharides.
Topics: Administration, Inhalation; Airway Resistance; Animals; Antigens; Bronchial Hyperreactivity; Broncho | 2000 |
Respiratory drive during carbachol challenge in allergic sheep.
Topics: Animals; Bronchoconstriction; Carbachol; Cholinergic Agonists; Hypersensitivity; Lung Volume Measure | 2001 |
Airway hyperreactivity to pharmacologic agents in rhesus monkeys cutaneously hypersensitive to Ascaris antigen.
Topics: Airway Resistance; Animals; Antigens; Ascaris; Carbachol; Disease Models, Animal; Dose-Response Rela | 1976 |
Characterization of sulfidopeptide leukotriene responses in sheep tracheal smooth muscle in vitro.
Topics: Animals; Ascaris; Borates; Carbachol; Cysteine; Female; Hypersensitivity; In Vitro Techniques; Indom | 1991 |
Airway effects of inhaled bradykinin, substance P, and neurokinin A in sheep.
Topics: Administration, Inhalation; Aerosols; Airway Resistance; Animals; Antigens, Helminth; Ascaris; Brady | 1991 |
Separation of late bronchial responses from airway hyperresponsiveness in allergic sheep.
Topics: Airway Resistance; Animals; Antigens; Bronchi; Carbachol; Hypersensitivity; Propionates; Quinolines; | 1991 |
Effects of dietary poly-unsaturated fatty acids on tracheal histaminergic and cholinergic responsiveness in experimental models of bronchial hypersensitivity and hyperreactivity.
Topics: alpha-Linolenic Acid; Animals; Bronchial Diseases; Carbachol; Dietary Fats; Fatty Acids, Unsaturated | 1987 |
A leukotriene and thromboxane inhibitor (Sch 37224) blocks antigen-induced immediate and late responses and airway hyperresponsiveness in allergic sheep.
Topics: Animals; Antigens; Bronchi; Carbachol; Dose-Response Relationship, Drug; Histamine; Hypersensitivity | 1988 |
Local parasympathetic mechanisms for ragweed-sensitized canine trachealis hyperresponsiveness.
Topics: Acetylcholine; Animals; Carbachol; Dogs; Dose-Response Relationship, Drug; Electric Stimulation; Hyp | 1987 |