Page last updated: 2024-11-07

carbachol and Hyperinsulinism

carbachol has been researched along with Hyperinsulinism in 9 studies

Carbachol: A slowly hydrolyzed CHOLINERGIC AGONIST that acts at both MUSCARINIC RECEPTORS and NICOTINIC RECEPTORS.

Hyperinsulinism: A syndrome with excessively high INSULIN levels in the BLOOD. It may cause HYPOGLYCEMIA. Etiology of hyperinsulinism varies, including hypersecretion of a beta cell tumor (INSULINOMA); autoantibodies against insulin (INSULIN ANTIBODIES); defective insulin receptor (INSULIN RESISTANCE); or overuse of exogenous insulin or HYPOGLYCEMIC AGENTS.

Research Excerpts

ExcerptRelevanceReference
"Insulin resistance is followed by an islet adaptation resulting in a compensating increase in insulin secretion and hyperinsulinemia."1.31Islet phospholipase A(2) activation is potentiated in insulin resistant mice. ( Ahrén, B; Karlsson, S; Simonsson, E, 2000)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (11.11)18.2507
2000's5 (55.56)29.6817
2010's3 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lubaczeuski, C2
Balbo, SL2
Ribeiro, RA2
Vettorazzi, JF1
Santos-Silva, JC1
Carneiro, EM2
Bonfleur, ML2
Mendes, MC1
Maller, AC1
Angelini, N1
Rafacho, A1
Boschero, AC1
Bosqueiro, JR1
Sørensen, H1
Winzell, MS1
Brand, CL1
Fosgerau, K1
Gelling, RW1
Nishimura, E1
Ahren, B2
Zawalich, WS2
Kelley, GG1
Simonsson, E1
Karlsson, S1
Rashid, S1
Shi, ZQ1
Niwa, M1
Mathoo, JM1
Vandelangeryt, ML1
Bilinski, D1
Lewis, GF1
Vranic, M1
Zawalich, KC1
Guerre-Millo, M1
Rouault, C1
Poulain, P1
André, J1
Poitout, V1
Peters, JM1
Gonzalez, FJ1
Fruchart, JC1
Reach, G1
Staels, B1

Reviews

1 review available for carbachol and Hyperinsulinism

ArticleYear
The pathogenesis of NIDDM: the role of the pancreatic beta cell.
    Diabetologia, 1995, Volume: 38, Issue:8

    Topics: Animals; Carbachol; Cholinergic Agents; Diabetes Mellitus; Diabetes Mellitus, Type 2; Glucose; Human

1995

Other Studies

8 other studies available for carbachol and Hyperinsulinism

ArticleYear
Vagotomy ameliorates islet morphofunction and body metabolic homeostasis in MSG-obese rats.
    Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 2015, Volume: 48, Issue:5

    Topics: Animals; Carbachol; Cell Count; Cholesterol; Cholinergic Agonists; Flavoring Agents; Glucose; Homeos

2015
Vagotomy diminishes obesity in cafeteria rats by decreasing cholinergic potentiation of insulin release.
    Journal of physiology and biochemistry, 2016, Volume: 72, Issue:4

    Topics: 1-Methyl-3-isobutylxanthine; Adipose Tissue; Animals; Body Weight; Carbachol; Colforsin; Cyclic AMP;

2016
Involvement of the cholinergic pathway in glucocorticoid-induced hyperinsulinemia in rats.
    Diabetes research and clinical practice, 2010, Volume: 87, Issue:2

    Topics: Animals; Blood Glucose; Carbachol; Dexamethasone; Drug Tolerance; Glucocorticoids; Glucose; Humans;

2010
Glucagon receptor knockout mice display increased insulin sensitivity and impaired beta-cell function.
    Diabetes, 2006, Volume: 55, Issue:12

    Topics: Animals; Arginine; Blood Glucose; Carbachol; Glucagon; Glucose; Glucose Clamp Technique; Glucose Tol

2006
Islet phospholipase A(2) activation is potentiated in insulin resistant mice.
    Biochemical and biophysical research communications, 2000, Jun-07, Volume: 272, Issue:2

    Topics: Animals; Arachidonic Acid; Blood Glucose; Body Weight; Carbachol; Diabetes Mellitus, Type 2; Dietary

2000
Beta-blockade, but not normoglycemia or hyperinsulinemia, markedly diminishes stress-induced hyperglycemia in diabetic dogs.
    Diabetes, 2000, Volume: 49, Issue:2

    Topics: Adrenergic beta-Antagonists; Animals; Blood Glucose; Carbachol; Diabetes Mellitus, Experimental; Dog

2000
A link between insulin resistance and hyperinsulinemia: inhibitors of phosphatidylinositol 3-kinase augment glucose-induced insulin secretion from islets of lean, but not obese, rats.
    Endocrinology, 2000, Volume: 141, Issue:9

    Topics: Androstadienes; Animals; Calcium; Carbachol; Cell Separation; Enzyme Inhibitors; Glucose; Hyperinsul

2000
PPAR-alpha-null mice are protected from high-fat diet-induced insulin resistance.
    Diabetes, 2001, Volume: 50, Issue:12

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Blood Glucose; Carbachol; Dietary Fats; Drug Synergism; Fastin

2001