carbachol has been researched along with Heart Failure in 13 studies
Carbachol: A slowly hydrolyzed CHOLINERGIC AGONIST that acts at both MUSCARINIC RECEPTORS and NICOTINIC RECEPTORS.
Heart Failure: A heterogeneous condition in which the heart is unable to pump out sufficient blood to meet the metabolic need of the body. Heart failure can be caused by structural defects, functional abnormalities (VENTRICULAR DYSFUNCTION), or a sudden overload beyond its capacity. Chronic heart failure is more common than acute heart failure which results from sudden insult to cardiac function, such as MYOCARDIAL INFARCTION.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The present study was designed to characterize the positive inotropic response to DPI 201-106 in isolated papillary muscle strips obtained from heart failure patients undergoing surgery." | 3.67 | Inotropic response to DPI 201-106 in the failing human heart. ( Böhm, M; Diet, F; Erdmann, E; Kemkes, B; Wankerl, M, 1989) |
| "Carbachol abolished the increase in light transients and cAMP accumulation induced by Org 30029 (1 mM), whereas it only partially attenuated the positive inotropic effect of Org 30029." | 1.29 | Effects of the positive inotropic agent Org 30029 on developed force and aequorin light transients in intact canine ventricular myocardium. ( Endoh, M; Kawabata, Y, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (30.77) | 18.7374 |
| 1990's | 3 (23.08) | 18.2507 |
| 2000's | 5 (38.46) | 29.6817 |
| 2010's | 1 (7.69) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hussain, RI | 2 |
| Qvigstad, E | 1 |
| Birkeland, JA | 1 |
| Eikemo, H | 1 |
| Glende, A | 1 |
| Sjaastad, I | 2 |
| Skomedal, T | 2 |
| Osnes, JB | 2 |
| Levy, FO | 2 |
| Krobert, KA | 2 |
| Aronsen, JM | 1 |
| Afzal, F | 1 |
| Wei, SK | 1 |
| Ruknudin, AM | 1 |
| Shou, M | 1 |
| McCurley, JM | 1 |
| Hanlon, SU | 1 |
| Elgin, E | 1 |
| Schulze, DH | 1 |
| Haigney, MC | 1 |
| Catalucci, D | 1 |
| Bang, ML | 1 |
| Condorelli, G | 1 |
| Brito-Martins, M | 1 |
| Harding, SE | 1 |
| Ali, NN | 1 |
| Kawabata, Y | 1 |
| Endoh, M | 1 |
| Shen, W | 1 |
| Wolin, MS | 1 |
| Hintze, TH | 1 |
| Borst, MM | 1 |
| Szalai, P | 1 |
| Herzog, N | 1 |
| Kübler, W | 1 |
| Strasser, RH | 1 |
| Nightingale, AK | 1 |
| Blackman, DJ | 1 |
| Ellis, GR | 1 |
| Schmitt, M | 1 |
| Morris-Thurgood, JA | 1 |
| Jones, EA | 1 |
| Frenneaux, MP | 1 |
| Gristwood, RW | 1 |
| English, TA | 1 |
| Wallwork, J | 1 |
| Sampford, KA | 1 |
| Owen, DA | 1 |
| Böhm, M | 1 |
| Diet, F | 1 |
| Kemkes, B | 1 |
| Wankerl, M | 1 |
| Erdmann, E | 1 |
| Bristow, MR | 1 |
| Minobe, W | 1 |
| Rasmussen, R | 1 |
| Hershberger, RE | 1 |
| Hoffman, BB | 1 |
| Vatner, DE | 1 |
| Lee, DL | 1 |
| Schwarz, KR | 1 |
| Longabaugh, JP | 1 |
| Fujii, AM | 1 |
| Vatner, SF | 1 |
| Homcy, CJ | 1 |
13 other studies available for carbachol and Heart Failure
| Article | Year |
|---|---|
Activation of muscarinic receptors elicits inotropic responses in ventricular muscle from rats with heart failure through myosin light chain phosphorylation.
Topics: Animals; Blood Pressure; Calcium; Carbachol; Cardiac Myosins; Cardiotonic Agents; Disease Models, An | 2009 |
The functional activity of inhibitory G protein (G(i)) is not increased in failing heart ventricle.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Carbachol; Cardiotonic Agents; GTP-Binding Pro | 2013 |
Muscarinic modulation of the sodium-calcium exchanger in heart failure.
Topics: Adrenergic beta-Agonists; Animals; Carbachol; Cardiac Pacing, Artificial; Cell Separation; Cells, Cu | 2007 |
Deciphering the beta-adrenergic response in human embryonic stem cell-derived-cardiac myocytes: closer to clinical use?
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Carbachol; Cell Differentiation; Cel | 2008 |
beta(1)- and beta(2)-adrenoceptor responses in cardiomyocytes derived from human embryonic stem cells: comparison with failing and non-failing adult human heart.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Adult; Animals; Carbachol; Cell Differentiati | 2008 |
Effects of the positive inotropic agent Org 30029 on developed force and aequorin light transients in intact canine ventricular myocardium.
Topics: Actin Cytoskeleton; Aequorin; Animals; Calcium; Carbachol; Cardiotonic Agents; Chordae Tendineae; Do | 1993 |
Defective endogenous nitric oxide-mediated modulation of cellular respiration in canine skeletal muscle after the development of heart failure.
Topics: 2,4-Dinitrophenol; Animals; Bradykinin; Carbachol; Cardiac Pacing, Artificial; Cell Respiration; Dog | 1997 |
Transregulation of adenylyl-cyclase-coupled inhibitory receptors in heart failure enhances anti-adrenergic effects on adult rat cardiomyocytes.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Analysis of Variance; Animals; Calcium Chloride; Carbac | 1999 |
Preservation of venous endothelial function in the forearm venous capacitance bed of patients with chronic heart failure despite arterial endothelial dysfunction.
Topics: Aged; Arteries; Carbachol; Chronic Disease; Endothelium, Vascular; Enzyme Inhibitors; Female; Forear | 2001 |
Analysis of responses to a selective phosphodiesterase III inhibitor, SK&F 94120, on isolated myocardium, including human ventricular myocardium from "end-stage" failure patients.
Topics: Animals; Carbachol; Cats; Female; Guinea Pigs; Heart Failure; Heart Ventricles; Humans; In Vitro Tec | 1987 |
Inotropic response to DPI 201-106 in the failing human heart.
Topics: Adenosine; Adult; Aged; Aging; Calcium; Carbachol; Electric Stimulation; Female; Heart Failure; Hemo | 1989 |
Alpha-1 adrenergic receptors in the nonfailing and failing human heart.
Topics: Carbachol; Heart Failure; Humans; Iodocyanopindolol; Myocardium; Norepinephrine; Phenethylamines; Ph | 1988 |
Impaired cardiac muscarinic receptor function in dogs with heart failure.
Topics: Adenylyl Cyclases; Animals; Atropine; Carbachol; Dogs; Female; Guanosine Triphosphate; Heart Failure | 1988 |