carbachol has been researched along with Glioma in 28 studies
Carbachol: A slowly hydrolyzed CHOLINERGIC AGONIST that acts at both MUSCARINIC RECEPTORS and NICOTINIC RECEPTORS.
Glioma: Benign and malignant central nervous system neoplasms derived from glial cells (i.e., astrocytes, oligodendrocytes, and ependymocytes). Astrocytes may give rise to astrocytomas (ASTROCYTOMA) or glioblastoma multiforme (see GLIOBLASTOMA). Oligodendrocytes give rise to oligodendrogliomas (OLIGODENDROGLIOMA) and ependymocytes may undergo transformation to become EPENDYMOMA; CHOROID PLEXUS NEOPLASMS; or colloid cysts of the third ventricle. (From Escourolle et al., Manual of Basic Neuropathology, 2nd ed, p21)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Glioma C62B cells were incubated for 18 h with [1-14C]arachidonic acid." | 7.67 | Cholinergic stimulation of arachidonic acid and phosphatidic acid metabolism in C62B glioma cells. ( DeGeorge, JJ; Lapetina, EG; McCarthy, KD; Morell, P, 1986) |
| " C6 rat glioma cells expressed H1-histamine, muscarinic cholinergic and adrenergic alpha1-receptors, stimulation of which resulted in phosphoinositide hydrolysis and increase in intracellular Ca2+ concentrations ([Ca2+]i)." | 3.70 | Effects of Sho-saiko-to, San'o-shashin-to and Scutellariae Radix on intracellular Ca2+ mobilization in C6 rat glioma cells. ( Kubo, M; Kyo, R; Nakahata, N; Ohizumi, Y; Sakakibara, I, 1998) |
| "The dinoflagellate toxin maitotoxin (MTX) elicited a sustained increase of [Ca2+]i in C6 glioma cells." | 3.68 | Maitotoxin effects are blocked by SK&F 96365, an inhibitor of receptor-mediated calcium entry. ( Daly, JW; Gusovsky, F; Soergel, DG; Yasumoto, T, 1992) |
| "Chronic pertussis toxin treatment (5 days) of NG108-15 neuroblastoma X glioma hybrid cells had no significant effect on basal cyclic AMP levels whereas it effectively blocked the inhibitory action of acute (10 min) exposure of carbachol (10(-4)M) on intracellular cyclic AMP accumulation, stimulated by prostaglandin E1." | 3.67 | Chronic exposure to pertussis toxin alters muscarinic receptor-mediated regulation of cyclic AMP metabolism in neuroblastoma x glioma NG108-15 hybrid cells. ( Askelöf, P; Bartfai, T; Gillenius, P; Westlind-Danielsson, A, 1988) |
| "The mechanisms of carbachol-induced muscarinic acetylcholine receptor (mAChR) down-regulation, and recovery following carbachol withdrawal, were studied in the neuroblastoma x glioma hybrid NG108-15 cell line by specific ligand binding assays." | 3.67 | Mechanism of agonist-induced down-regulation and subsequent recovery of muscarinic acetylcholine receptors in a clonal neuroblastoma x glioma hybrid cell line. ( Berman, JD; Middleton, W; Ray, P, 1989) |
| "Chronic treatment of neuroblastoma X glioma hybrid cells (NG 108-15) with the muscarinic cholinergic agonist carbachol, which acutely inhibits adenylate cyclase, resulted in a 104 +/- 10% increase in PGE1-stimulated cAMP accumulation." | 3.67 | Muscarinic cholinergic receptor-induced enhancement of PGE1-stimulated cAMP accumulation in neuroblastoma X glioma cells: prevention by pertussis toxin. ( Hoffman, BB; Thomas, JM, 1986) |
| "Glioma C62B cells were incubated for 18 h with [1-14C]arachidonic acid." | 3.67 | Cholinergic stimulation of arachidonic acid and phosphatidic acid metabolism in C62B glioma cells. ( DeGeorge, JJ; Lapetina, EG; McCarthy, KD; Morell, P, 1986) |
| "The cholinergic agonist carbachol, epinephrine, and the opiate morphine all inhibit prostaglandin E1 (PGE1)-stimulated adenylate cyclase in homogenates from the neuroblastoma-glioma hybrid NG108-15." | 3.66 | Specific muscarinic-cholinergic desensitization in the neuroblastoma-glioma hybrid NG108-15. ( Clark, RB; Green, DA, 1982) |
| "Carbachol was a chemoattractant for microglia and decreased their phagocytic activity." | 1.43 | The subpopulation of microglia expressing functional muscarinic acetylcholine receptors expands in stroke and Alzheimer's disease. ( Endres, M; Kettenmann, H; Kronenberg, G; Matyash, V; Meier, MA; Pannell, M; Prinz, V; Szulzewsky, F; Waiczies, S; Wolf, SA, 2016) |
| "Paclitaxel (which promotes tubulin polymerization) stimulated hexose uptake by about 25%." | 1.30 | Role of microtubules in glucose uptake by C6 glioma cells. ( Gao, Y; Kunapuli, SP; Ravindra, R; Singh, LD; Singh, SP, 1998) |
| "Pretreatment with carbachol for 30 hr led to an enhanced cAMP response which decayed in two components, a rapid component and an additional, more stable component which persisted for at least 2 hr after withdrawal of carbachol." | 1.28 | Activation of muscarinic cholinergic receptors in mouse neuroblastoma x rat glioma hybrid cells: rapid induction of enhanced capacity of prostaglandin E1 receptors to stimulate cyclic AMP accumulation. ( Hoffman, BB; Thomas, JM, 1990) |
| "Carbachol treatment of cells resulted in down-regulation of muscarinic cholinergic receptors to 45." | 1.27 | Agonist-induced down-regulation of muscarinic cholinergic and alpha 2-adrenergic receptors after inactivation of Ni by pertussis toxin. ( Hoffman, BB; Thomas, JM, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 14 (50.00) | 18.7374 |
| 1990's | 13 (46.43) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (3.57) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pannell, M | 1 |
| Meier, MA | 1 |
| Szulzewsky, F | 1 |
| Matyash, V | 1 |
| Endres, M | 1 |
| Kronenberg, G | 1 |
| Prinz, V | 1 |
| Waiczies, S | 1 |
| Wolf, SA | 1 |
| Kettenmann, H | 1 |
| Wüster, M | 1 |
| Costa, T | 1 |
| Maloteaux, JM | 1 |
| Gossuin, A | 1 |
| Pauwels, PJ | 1 |
| Laduron, PM | 1 |
| Green, DA | 1 |
| Clark, RB | 1 |
| Thomas, JM | 4 |
| Frazier, JS | 1 |
| Hu, ZW | 1 |
| Hoffman, BB | 4 |
| Hescheler, J | 1 |
| Buxbaum, JD | 1 |
| Ruefli, AA | 1 |
| Parker, CA | 1 |
| Cypess, AM | 1 |
| Greengard, P | 1 |
| Civan, MM | 1 |
| Robbins, J | 1 |
| Broad, S | 1 |
| Rozengurt, E | 1 |
| Brown, DA | 1 |
| Singh, SP | 3 |
| Gao, Y | 3 |
| Kunapuli, SP | 3 |
| Ravindra, R | 3 |
| Cachero, TG | 1 |
| Morielli, AD | 1 |
| Peralta, EG | 1 |
| Singh, LD | 1 |
| Kyo, R | 1 |
| Nakahata, N | 1 |
| Sakakibara, I | 1 |
| Kubo, M | 1 |
| Ohizumi, Y | 1 |
| Gullis, RJ | 1 |
| Traber, J | 2 |
| Fischer, K | 2 |
| Buchen, C | 2 |
| Hamprecht, B | 2 |
| Lichtshtein, D | 1 |
| Boone, G | 1 |
| Blume, A | 1 |
| Eichberg, J | 1 |
| Shein, HM | 1 |
| Hauser, G | 1 |
| Soergel, DG | 1 |
| Yasumoto, T | 1 |
| Daly, JW | 1 |
| Gusovsky, F | 1 |
| Wei, JW | 1 |
| Yeh, SR | 1 |
| Murphy, S | 1 |
| Welk, G | 1 |
| Thwin, SS | 1 |
| Westlind-Danielsson, A | 1 |
| Gillenius, P | 1 |
| Askelöf, P | 1 |
| Bartfai, T | 1 |
| Ray, P | 1 |
| Middleton, W | 1 |
| Berman, JD | 1 |
| Howlett, AC | 1 |
| Qualy, JM | 1 |
| Khachatrian, LL | 1 |
| DeGeorge, JJ | 1 |
| Morell, P | 1 |
| McCarthy, KD | 1 |
| Lapetina, EG | 1 |
| Gilman, AG | 1 |
| Nirenberg, M | 1 |
1 review available for carbachol and Glioma
| Article | Year |
|---|---|
The opioid-induced desensitization (tolerance) in neuroblastoma x glioma NG 108-15 hybrid cells: results from receptor uncoupling.
Topics: Animals; Bacterial Toxins; Carbachol; Cell Membrane; Cyclic AMP; Drug Tolerance; Enkephalin, Leucine | 1984 |
27 other studies available for carbachol and Glioma
| Article | Year |
|---|---|
The subpopulation of microglia expressing functional muscarinic acetylcholine receptors expands in stroke and Alzheimer's disease.
Topics: Alzheimer Disease; Animals; Brain; Carbachol; Disease Models, Animal; Female; Glioma; Macrophages; M | 2016 |
Short-term disappearance of muscarinic cell surface receptors in carbachol-induced desensitization.
Topics: Animals; Carbachol; Cell Line; Cell Membrane; Cerebellum; Glioma; Hybrid Cells; N-Methylscopolamine; | 1983 |
Specific muscarinic-cholinergic desensitization in the neuroblastoma-glioma hybrid NG108-15.
Topics: Adenylyl Cyclases; Alprostadil; Animals; Atropine; Carbachol; Cell Line; Glioma; Hybrid Cells; Mice; | 1982 |
Phosphorylation of cyclic AMP response element-binding protein and induction of c-fos gene expression on withdrawal from chronic treatment with carbachol in NG108-15 cells.
Topics: Alprostadil; Animals; Carbachol; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Gene Expre | 1995 |
Whole-cell clamp analysis for G-protein regulation of channels.
Topics: Adenosine Diphosphate Ribose; Animals; Calcium Channels; Carbachol; Cholera Toxin; Electrophysiology | 1994 |
Calcium regulates processing of the Alzheimer amyloid protein precursor in a protein kinase C-independent manner.
Topics: Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Calcium; Calcium-Transporting ATPase | 1994 |
Whole-cell recording of neuroblastoma x glioma cells during downregulation of a major substrate, 80K/MARCKS, of protein kinase C.
Topics: Animals; Carbachol; Cell Differentiation; Down-Regulation; Electrophysiology; Glioma; Hybrid Cells; | 1993 |
Glucose uptake by C6 glioma cells is mediated by G(q alpha).
Topics: Animals; Carbachol; Deoxyglucose; Glioma; Glucose; GTP-Binding Proteins; Guanylyl Imidodiphosphate; | 1998 |
The small GTP-binding protein RhoA regulates a delayed rectifier potassium channel.
Topics: ADP Ribose Transferases; Animals; Botulinum Toxins; Carbachol; Cell Membrane; Cells, Cultured; Enzym | 1998 |
Role of microtubules in glucose uptake by C6 glioma cells.
Topics: Animals; Carbachol; Colchicine; Deoxyglucose; Dose-Response Relationship, Drug; Glioma; Glucose Tran | 1998 |
Effects of Sho-saiko-to, San'o-shashin-to and Scutellariae Radix on intracellular Ca2+ mobilization in C6 rat glioma cells.
Topics: Animals; Antineoplastic Agents; Calcium; Carbachol; Drugs, Chinese Herbal; Glioma; Histamine; Hydrol | 1998 |
Ethanol inhibits G-protein-mediated glucose uptake by C6 glioma cells.
Topics: Animals; Carbachol; Cell Count; Cell Survival; Culture Media; Deoxyglucose; Ethanol; Glioma; Glucose | 1999 |
Effects of cholinergic agents and sodium ions on the levels of guanosine and adenosine 3':5'-cyclic monophosphates in neuroblastoma and neuroblastoma X glioma hybrid cells.
Topics: Acetylcholine; Carbachol; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Drug Interaction | 1975 |
Muscarinic receptor regulation of NG108-15 adenylate cyclase: requirement for Na+ and GTP.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Acetylcholine; Adenylyl Cyclase Inhibitors; Adenylyl | 1979 |
Phospholipid metabolism in cultured neuroblastoma and glioma cells incubated with carbamylcholine and norepinephrine.
Topics: Animals; Carbachol; Clone Cells; Glioma; Neoplasms, Experimental; Neuroblastoma; Norepinephrine; Pho | 1975 |
Muscarinic response to acetylcholine in neuroblastoma times glioma hybrid cells.
Topics: Acetylcholine; Animals; Atropine; Carbachol; Clone Cells; Glioma; Hybrid Cells; Mice; Neuroblastoma; | 1975 |
Maitotoxin effects are blocked by SK&F 96365, an inhibitor of receptor-mediated calcium entry.
Topics: Calcium; Calcium Channel Blockers; Carbachol; Endothelins; Glioma; Imidazoles; Insulin; Marine Toxin | 1992 |
Effects of insulin on glucose uptake in cultured cells from the central nervous system of rodent.
Topics: Animals; Calcium; Carbachol; Central Nervous System; Choline; Deoxyglucose; Glioma; Insulin; Kinetic | 1991 |
Stimulation of thromboxane release from primary cell cultures derived from human astrocytic glioma biopsies.
Topics: Astrocytes; Carbachol; Epidermal Growth Factor; Flow Cytometry; Glial Fibrillary Acidic Protein; Gli | 1990 |
Activation of muscarinic cholinergic receptors in mouse neuroblastoma x rat glioma hybrid cells: rapid induction of enhanced capacity of prostaglandin E1 receptors to stimulate cyclic AMP accumulation.
Topics: Adenylate Cyclase Toxin; Alprostadil; Animals; Carbachol; Cyclic AMP; Glioma; GTP-Binding Proteins; | 1990 |
Agonist-induced down-regulation of muscarinic cholinergic and alpha 2-adrenergic receptors after inactivation of Ni by pertussis toxin.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine Diphosphate Ribose; Adenylate Cyclase Toxin; Adenylyl Cyclase | 1986 |
Chronic exposure to pertussis toxin alters muscarinic receptor-mediated regulation of cyclic AMP metabolism in neuroblastoma x glioma NG108-15 hybrid cells.
Topics: 1-Methyl-3-isobutylxanthine; Alprostadil; Atropine; Carbachol; Cyclic AMP; Glioma; Hybrid Cells; Neu | 1988 |
Mechanism of agonist-induced down-regulation and subsequent recovery of muscarinic acetylcholine receptors in a clonal neuroblastoma x glioma hybrid cell line.
Topics: Animals; Bacitracin; Benzimidazoles; Carbachol; Cell Membrane; Colchicine; Endocytosis; Glioma; Hybr | 1989 |
Involvement of Gi in the inhibition of adenylate cyclase by cannabimimetic drugs.
Topics: Adenosine Diphosphate Ribose; Adenylate Cyclase Toxin; Adenylyl Cyclase Inhibitors; Animals; Cannabi | 1986 |
Muscarinic cholinergic receptor-induced enhancement of PGE1-stimulated cAMP accumulation in neuroblastoma X glioma cells: prevention by pertussis toxin.
Topics: Adenosine Diphosphate Ribose; Adenylate Cyclase Toxin; Adenylyl Cyclases; Alprostadil; Atropine; Car | 1986 |
Cholinergic stimulation of arachidonic acid and phosphatidic acid metabolism in C62B glioma cells.
Topics: Acetylcholine; Animals; Arachidonic Acid; Arachidonic Acids; Atropine; Calcimycin; Carbachol; Cell L | 1986 |
Effect of catecholamines on the adenosine 3':5'-cyclic monophosphate concentrations of clonal satellite cells of neurons.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Aminobutyrates; Animals; Astrocytoma; Car | 1971 |