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carbachol and Glaucoma

carbachol has been researched along with Glaucoma in 48 studies

Carbachol: A slowly hydrolyzed CHOLINERGIC AGONIST that acts at both MUSCARINIC RECEPTORS and NICOTINIC RECEPTORS.

Glaucoma: An ocular disease, occurring in many forms, having as its primary characteristics an unstable or a sustained increase in the intraocular pressure which the eye cannot withstand without damage to its structure or impairment of its function. The consequences of the increased pressure may be manifested in a variety of symptoms, depending upon type and severity, such as excavation of the optic disk, hardness of the eyeball, corneal anesthesia, reduced visual acuity, seeing of colored halos around lights, disturbed dark adaptation, visual field defects, and headaches. (Dictionary of Visual Science, 4th ed)

Research Excerpts

ExcerptRelevanceReference
"A 78-year-old woman with bilateral exfoliation glaucoma who was receiving warfarin, 2 mg daily, for systemic anticoagulation developed acute visual loss in the right eye several hours after pupillary dilation."7.70Hyphema associated with pupillary dilation in a patient with exfoliation glaucoma and warfarin therapy. ( Greenfield, DS; Liebmann, JM; Ritch, R, 1999)
"Carbachol instilled in 125 eyes at the time of extracapsular cataract extraction and posterior chamber lens insertion had a statistically significant effect on lowering the postoperative intraocular pressure (IOP) at 24 hours (average IOP 14."7.67Effect of carbachol on postoperative intraocular pressure. ( Wood, TO, 1988)
"In 39 selected patients with open-angle glaucoma, in whom pressure regulation with Timolol alone was inadequate, success was achieved by using this drug in combination with various other glaucoma drugs over treatment periods of 12 to 18 months."7.66[Timolol in combination with other glaucoma drugs (author's transl)]. ( Merkle, W, 1981)
"The authors report on seven patients with narrow-angle glaucoma treated for up to six months with Timolol eye drops."7.66[Treatment of narrow-angle glaucoma with timolol (author's transl)]. ( Demmler, N; Müller-Bardorff, G, 1980)
"45 patients with ocular hypertension or open-angle glaucoma were tested to see if, and to what extent timolol and three other different parasympathicomimetics (pilocarpine 2%, carbachol 1."7.66[The effect of timolol and parasympathicomimetica in the treatment of the elevated intraocular pressure (author's transl)]. ( Ober, M; Scharrer, A, 1979)
"5% four times a day, or 250 mg of acetazolamide twice a day to 44 patients with chronic open-angle glaucoma."7.66Evaluation of timolol maleate combination therapy in chronic open-angle glaucoma. ( Keates, EU, 1979)
"A double-blind crossover study in seven patients with glaucoma and obstructive lung disease revealed a considerable and significant bronchoconstrictive side effect on topically administered timolol maleat."5.05[Bronchoconstrictive side effects of timolol eye drops in patients with obstructive lung disease]. ( Bachofen, H; Flammer, J; Landolt, M; Vonwil, A, 1981)
"A 78-year-old woman with bilateral exfoliation glaucoma who was receiving warfarin, 2 mg daily, for systemic anticoagulation developed acute visual loss in the right eye several hours after pupillary dilation."3.70Hyphema associated with pupillary dilation in a patient with exfoliation glaucoma and warfarin therapy. ( Greenfield, DS; Liebmann, JM; Ritch, R, 1999)
"Carbachol instilled in 125 eyes at the time of extracapsular cataract extraction and posterior chamber lens insertion had a statistically significant effect on lowering the postoperative intraocular pressure (IOP) at 24 hours (average IOP 14."3.67Effect of carbachol on postoperative intraocular pressure. ( Wood, TO, 1988)
"This paper will discuss the pharmacology and mechanism of action of various drugs used to treat glaucoma, such as epinephrine, pilocarpine, carbonic anhydrase inhibitors and a new class of drugs to be used in ophthalmology, the beta adrenergic blockers, with particular reference to timolol."3.66Basic pharmacology of some glaucoma drugs with emphasis on new information and new developments. ( Zimmerman, TJ, 1980)
"In 39 selected patients with open-angle glaucoma, in whom pressure regulation with Timolol alone was inadequate, success was achieved by using this drug in combination with various other glaucoma drugs over treatment periods of 12 to 18 months."3.66[Timolol in combination with other glaucoma drugs (author's transl)]. ( Merkle, W, 1981)
"From an original group of 36 Patients (15 with relatively advanced chronic open-angle glaucoma and 21 with ocular hypertension) 21 (seven glucoma and 14 ocular hypertension) were well controlled with Timolol alone or in combination with other pressure-lowering drugs after a three years' observation period."3.66[Long-term therapy with timolol for three years (author's transl)]. ( Bischoff, P; Urner-Bloch, U, 1981)
"Pilocarpine, a parasympathomimetic drug used in the treatment of glaucoma, produces a variety of ocular and systemic adverse reactions."3.66Miotics: side effects and ways to avoid them. ( Wheeler, TM; Zimmerman, TJ, 1982)
"The tertiary nitrogen derivative of carbachol, N-demethylated carbachol, was synthesized to produce a drug that could be used as an alternative to pilocarpine in the treatment of open-angle glaucoma."3.66Effects of N-demethylated carbachol on iris and ciliary muscles. ( Chiou, GC; Trzeciakowski, J, 1980)
"The authors report on seven patients with narrow-angle glaucoma treated for up to six months with Timolol eye drops."3.66[Treatment of narrow-angle glaucoma with timolol (author's transl)]. ( Demmler, N; Müller-Bardorff, G, 1980)
"45 patients with ocular hypertension or open-angle glaucoma were tested to see if, and to what extent timolol and three other different parasympathicomimetics (pilocarpine 2%, carbachol 1."3.66[The effect of timolol and parasympathicomimetica in the treatment of the elevated intraocular pressure (author's transl)]. ( Ober, M; Scharrer, A, 1979)
"5% four times a day, or 250 mg of acetazolamide twice a day to 44 patients with chronic open-angle glaucoma."3.66Evaluation of timolol maleate combination therapy in chronic open-angle glaucoma. ( Keates, EU, 1979)
"After laser treatment, intraocular pressure (IOP) was elevated 1."1.36Altered calcium signaling in an experimental model of glaucoma. ( Akerman, KE; Kaarniranta, K; Kalesnykas, G; Larsson, KP; Niittykoski, M; Uusitalo, H, 2010)
"Intraocular pressures were measured preoperatively and 20 to 24 hours postoperatively."1.28Comparison of postoperative intraocular pressures after use of Miochol and Miostat. ( Boggs, MB; McKinzie, JW, 1989)

Research

Studies (48)

TimeframeStudies, this research(%)All Research%
pre-199044 (91.67)18.7374
1990's2 (4.17)18.2507
2000's1 (2.08)29.6817
2010's1 (2.08)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Niittykoski, M1
Kalesnykas, G1
Larsson, KP1
Kaarniranta, K1
Akerman, KE1
Uusitalo, H1
VAN BEUNINGEN, EG1
KNUPFFER, N1
EIDEL'MAN, BM1
Shaffer, RN1
Hetherington, J1
Zimmerman, TJ4
Merkle, W1
Reibaldi, A1
Giummarra, C1
Ciracì, G1
Leader, B1
Kaufman, HE1
Molteno, AC1
Ancker, E1
Van Biljon, G1
Urner-Bloch, U1
Bischoff, P1
Vonwil, A1
Landolt, M1
Flammer, J1
Bachofen, H1
Wheeler, TM1
Dancheva, LD1
Zhukova, VN1
Chiou, GC2
Lowden, BA1
Trzeciakowski, J2
Chiou, CY1
Gelatt, KN1
Demmler, N1
Müller-Bardorff, G1
Taniguchi, T1
Kitazawa, Y1
Greenfield, DS1
Liebmann, JM1
Ritch, R1
Zhang, X1
Wang, N1
Schroeder, A1
Erickson, KA1
Ober, M1
Scharrer, A1
Keates, EU1
Pitrová, S1
Kalvodová, B1
McKinzie, JW1
Boggs, MB1
Wood, TO1
Hiatt, RL1
Deutsch, AR1
Ringer, C1
Ourgaud, AG1
Tassy, A1
Rouanet, G1
Holland, MG1
Imaizumi, K1
Atsumi, K1
Tazawa, Y1
Kobayashi, H1
Linnert, D1
Anderson, DR1
Grant, WM1
Weinstock, FJ1
Dalkowska, A1
Bartkowska-Orlowska, M1
Gogolkiewicz, J1
Törnqvist, G1
Krejcí, L2
Harrison, R2
Sugar, HS1
Kraus, H1
Lastůvková, M1
Niemeyer, G2
Drance, SM2
Kanski, JJ1
Fortenberry, B1
Kagawa, CM1
Leaders, FE2
McDonald, TO1
Hodges, JW1
Borgmann, AR1
Flindall, RJ1

Reviews

3 reviews available for carbachol and Glaucoma

ArticleYear
Advances in ocular pharmacology.
    Annual review of pharmacology and toxicology, 1980, Volume: 20

    Topics: Animals; Cannabis; Carbachol; Cytochalasin B; Epinephrine; Eye; Eye Diseases; Glaucoma; Humans; Idox

1980
A risk-benefit assessment of drugs used in the management of glaucoma.
    Drug safety, 1994, Volume: 11, Issue:1

    Topics: Adrenergic Agonists; Carbachol; Carbonic Anhydrase Inhibitors; Drug Therapy, Combination; Glaucoma;

1994
Autonomic drugs in ophthalmology: some problems and promises. I. Directly and indirectly acting parasympathomimetic drugs.
    Annals of ophthalmology, 1974, Volume: 6, Issue:5

    Topics: Administration, Topical; Animals; Carbachol; Cataract; Cholinesterase Inhibitors; Contact Lenses, Hy

1974

Trials

3 trials available for carbachol and Glaucoma

ArticleYear
[Bronchoconstrictive side effects of timolol eye drops in patients with obstructive lung disease].
    Schweizerische medizinische Wochenschrift, 1981, May-09, Volume: 111, Issue:19

    Topics: Aged; Bronchial Spasm; Carbachol; Clinical Trials as Topic; Double-Blind Method; Female; Glaucoma; H

1981
Effect of glaumarin upon glaucoma.
    Transactions of the Ophthalmological Society of New Zealand, 1973, Volume: 25

    Topics: Adolescent; Adult; Carbachol; Female; Glaucoma; Humans; Intraocular Pressure; Male; Middle Aged; Pil

1973
[Carbachol compared with pilocarpine in the therapy of glaucoma simplex].
    Klinische Monatsblatter fur Augenheilkunde, 1972, Volume: 161, Issue:3

    Topics: Carbachol; Glaucoma; Humans; Intraocular Pressure; Ointments; Ophthalmic Solutions; Pilocarpine; Ton

1972

Other Studies

42 other studies available for carbachol and Glaucoma

ArticleYear
Altered calcium signaling in an experimental model of glaucoma.
    Investigative ophthalmology & visual science, 2010, Volume: 51, Issue:12

    Topics: Adenosine Triphosphate; Animals; Axons; Calcium; Calcium Signaling; Carbachol; Cholinergic Agonists;

2010
[Two years experience with doryl Z (Merck), a new drug for chronic simple glaucoma].
    Klinische Monatsblatter fur Augenheilkunde und fur augenarztliche Fortbildung, 1952, Volume: 121, Issue:3

    Topics: Carbachol; Glaucoma; Glaucoma, Open-Angle; Humans; Parasympathomimetics

1952
[Comparison of new drugs in therapy of glaucoma (mintacol, floropryl, doryl Z)].
    Klinische Monatsblatter fur Augenheilkunde und fur augenarztliche Fortbildung, 1952, Volume: 121, Issue:3

    Topics: Carbachol; Glaucoma; Humans; Isoflurophate; Parasympathomimetics

1952
[Relationship between the degree of pupil contraction and the hypotensive activity of carbocholine, polocarpine, proserine and eserine].
    Trudy Leningradskogo sanitarno-gigienicheskogo meditsinskogo instituta, 1960, Volume: 57

    Topics: Carbachol; Glaucoma; Humans; Neostigmine; Parasympathomimetics; Physostigmine; Pilocarpine; Pupil

1960
Anticholinesterase drugs and cataracts.
    Transactions of the American Ophthalmological Society, 1966, Volume: 64

    Topics: Adult; Aged; Carbachol; Cataract; Cholinesterase Inhibitors; Echothiophate Iodide; Female; Glaucoma;

1966
Basic pharmacology of some glaucoma drugs with emphasis on new information and new developments.
    Australian journal of ophthalmology, 1980, Volume: 8, Issue:2

    Topics: Acetazolamide; Adrenergic beta-Antagonists; Biotransformation; Carbachol; Carbonic Anhydrase Inhibit

1980
[Timolol in combination with other glaucoma drugs (author's transl)].
    Klinische Monatsblatter fur Augenheilkunde, 1981, Volume: 178, Issue:1

    Topics: Acetazolamide; Aged; Carbachol; Drug Therapy, Combination; Epinephrine; Female; Glaucoma; Humans; Ma

1981
[The effect of antiglaucoma drugs on the depth of the anterior chamber (I)].
    Bollettino della Societa italiana di biologia sperimentale, 1982, Aug-15, Volume: 58, Issue:15

    Topics: Adult; Anterior Chamber; Carbachol; Clonidine; Glaucoma; Humans; Middle Aged; Miotics; Moxisylyte; P

1982
Surgical technique for advanced juvenile glaucoma.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1984, Volume: 102, Issue:1

    Topics: Acetazolamide; Adolescent; Adult; Carbachol; Child; Child, Preschool; Colchicine; Drainage; Follow-U

1984
[Long-term therapy with timolol for three years (author's transl)].
    Klinische Monatsblatter fur Augenheilkunde, 1981, Volume: 179, Issue:1

    Topics: Acetazolamide; Carbachol; Drug Therapy, Combination; Glaucoma; Glaucoma, Open-Angle; Humans; Intraoc

1981
Miotics: side effects and ways to avoid them.
    Ophthalmology, 1982, Volume: 89, Issue:1

    Topics: Carbachol; Cholinesterase Inhibitors; Glaucoma; Humans; Miotics; Parasympathomimetics; Pilocarpine

1982
[Remote results in the treatment of the initial stage of glaucoma with miotics].
    Oftalmologicheskii zhurnal, 1981, Volume: 36, Issue:1

    Topics: Carbachol; Drug Therapy, Combination; Follow-Up Studies; Glaucoma; Humans; Intraocular Pressure; Mio

1981
Recent advances in antiglaucoma drugs.
    Biochemical pharmacology, 1981, Jan-15, Volume: 30, Issue:2

    Topics: Cannabis; Carbachol; Glaucoma; Humans; Parasympathomimetics; Sclera; Timolol; Trabecular Meshwork

1981
Error in glaucoma therapy.
    Canadian Medical Association journal, 1980, Aug-09, Volume: 123, Issue:3

    Topics: Carbachol; Female; Glaucoma; Humans; Medication Errors; Middle Aged; Ophthalmic Solutions

1980
Effects of N-demethylated carbachol on iris and ciliary muscles.
    Journal of pharmaceutical sciences, 1980, Volume: 69, Issue:3

    Topics: Animals; Carbachol; Cilia; Dealkylation; Dogs; Eye; Glaucoma; In Vitro Techniques; Iris; Muscle, Smo

1980
Reduction of intraocular pressure in glaucomatous dogs by a new cholinergic drug.
    Investigative ophthalmology & visual science, 1980, Volume: 19, Issue:10

    Topics: Animals; Carbachol; Dogs; Glaucoma; Intraocular Pressure; Parasympathomimetics; Pilocarpine; Rabbits

1980
[Treatment of narrow-angle glaucoma with timolol (author's transl)].
    Klinische Monatsblatter fur Augenheilkunde, 1980, Volume: 177, Issue:1

    Topics: Aged; Carbachol; Drug Therapy, Combination; Female; Glaucoma; Humans; Intraocular Pressure; Male; Mi

1980
Hyphema associated with pupillary dilation in a patient with exfoliation glaucoma and warfarin therapy.
    American journal of ophthalmology, 1999, Volume: 128, Issue:1

    Topics: Aged; Anticoagulants; Atrial Fibrillation; Carbachol; Cerebrovascular Disorders; Drug Therapy, Combi

1999
Expression of adenylate cyclase subtypes II and IV in the human outflow pathway.
    Investigative ophthalmology & visual science, 2000, Volume: 41, Issue:5

    Topics: Adenylyl Cyclases; Aged; Aged, 80 and over; Carbachol; Cells, Cultured; Cholinergic Agonists; Ciliar

2000
What's new for the medical therapy of glaucoma?
    Annals of ophthalmology, 1978, Volume: 10, Issue:5

    Topics: Adrenergic beta-Antagonists; Carbachol; Epinephrine; Glaucoma; Humans

1978
[The effect of timolol and parasympathicomimetica in the treatment of the elevated intraocular pressure (author's transl)].
    Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie. Albrecht von Graefe's archive for clinical and experimental ophthalmology, 1979, Jul-02, Volume: 211, Issue:1

    Topics: Carbachol; Drug Administration Schedule; Glaucoma; Humans; Intraocular Pressure; Parasympathomimetic

1979
Evaluation of timolol maleate combination therapy in chronic open-angle glaucoma.
    American journal of ophthalmology, 1979, Volume: 88, Issue:3 Pt 2

    Topics: Acetazolamide; Adult; Aged; Carbachol; Drug Therapy, Combination; Epinephrine; Female; Glaucoma; Hum

1979
[General symptoms following administration of isopto-carbachol].
    Ceskoslovenska oftalmologie, 1978, Volume: 34, Issue:5

    Topics: Adolescent; Adult; Aged; Carbachol; Cardiovascular Diseases; Child; Female; Follow-Up Studies; Glauc

1978
Comparison of postoperative intraocular pressures after use of Miochol and Miostat.
    Journal of cataract and refractive surgery, 1989, Volume: 15, Issue:2

    Topics: Acetazolamide; Acetylcholine; Carbachol; Cataract Extraction; Glaucoma; Humans; Intraocular Pressure

1989
Effect of carbachol on postoperative intraocular pressure.
    Journal of cataract and refractive surgery, 1988, Volume: 14, Issue:6

    Topics: Carbachol; Cataract; Cataract Extraction; Glaucoma; Humans; Intraocular Pressure; Postoperative Comp

1988
Low tension glaucoma.
    Annals of ophthalmology, 1971, Volume: 3, Issue:1

    Topics: Aged; Bronchitis; Carbachol; Cardiovascular Diseases; Coronary Disease; Diabetes Complications; Fema

1971
[Carbaminoyl choline in the treatment of chronic open-angle glaucoma. Comparison with pilocarpin].
    Bulletin des societes d'ophtalmologie de France, 1973, Volume: 73, Issue:1

    Topics: Aqueous Humor; Benzalkonium Compounds; Carbachol; Drug Therapy, Combination; Glaucoma; Humans; Hyper

1973
The influence of position on intraocular pressure.
    Investigative ophthalmology, 1973, Volume: 12, Issue:3

    Topics: Acetazolamide; Carbachol; Echothiophate Iodide; Epinephrine; Glaucoma; Humans; Intraocular Pressure;

1973
Glaucoma detection: a three-step technique.
    American family physician, 1973, Volume: 8, Issue:3

    Topics: Acute Disease; Adult; Age Factors; Aqueous Humor; Carbachol; Carbonic Anhydrase Inhibitors; Cholines

1973
[Carbacholine in the treatment of primary glaucoma].
    Klinika oczna, 1973, Volume: 43, Issue:2

    Topics: Adult; Aged; Carbachol; Drug Evaluation; Drug Tolerance; Female; Glaucoma; Humans; Male; Middle Aged

1973
Accommodation in monkeys: some pharmacological and physiological aspects.
    Acta ophthalmologica, 1967, Volume: 45, Issue:3

    Topics: Accommodation, Ocular; Animals; Blood Pressure; Carbachol; Glaucoma; Haplorhini; Parasympathomimetic

1967
[Comparative study of effects of antiglaucoma drugs on corneal epithelium in tissue culture].
    Ceskoslovenska oftalmologie, 1971, Volume: 27, Issue:3

    Topics: Animals; Carbachol; Cornea; Culture Techniques; Dogs; Epinephrine; Epithelium; Glaucoma; Guanethidin

1971
Principles of medical management in chronic open angle glaucoma.
    Annals of ophthalmology, 1971, Volume: 3, Issue:6

    Topics: Administration, Oral; Adult; Aged; Aqueous Humor; Carbachol; Carbonic Anhydrase Inhibitors; Cardiac

1971
[Isopto-carbachol in the therapy of glaucoma].
    Ceskoslovenska oftalmologie, 1970, Volume: 26, Issue:4

    Topics: Aged; Carbachol; Female; Glaucoma; Humans; Intraocular Pressure; Male; Middle Aged

1970
Antiglaucoma drug effects on corneal epithelium. A comparative study in tissue culture.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1970, Volume: 84, Issue:6

    Topics: Animals; Carbachol; Cornea; Culture Techniques; Echothiophate Iodide; Epinephrine; Epithelium; Glauc

1970
[Guanethidine in combination with pilocarpine in glaucoma simplex].
    Klinische Monatsblatter fur Augenheilkunde, 1967, Volume: 150, Issue:6

    Topics: Carbachol; Drug Synergism; Glaucoma; Guanethidine; Humans; Intraocular Pressure; Ophthalmic Solution

1967
Medical management of glaucoma.
    International ophthalmology clinics, 1967,Spring, Volume: 7, Issue:1

    Topics: Acute Disease; Carbachol; Carbonic Anhydrase Inhibitors; Child; Cholinesterase Inhibitors; Chronic D

1967
Carbaminoylcholine in glaucoma simplex. Comparative tonographic study of the effect of pilocarpine-HC1 and carbaminoylcholine in chronic simple glaucoma.
    Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde, 1968, Volume: 156, Issue:2

    Topics: Adult; Aqueous Humor; Carbachol; Female; Glaucoma; Humans; Male; Middle Aged; Pilocarpine; Tonometry

1968
Miotics.
    The British journal of ophthalmology, 1968, Volume: 52, Issue:12

    Topics: Acetylcholine; Anterior Chamber; Carbachol; Cataract; Cholinesterase Inhibitors; Cysts; Echothiophat

1968
A chemically induced experimental ocular hypertension for evaluating drug effects in albino rabbits.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1969, Volume: 131, Issue:2

    Topics: Animals; Carbachol; Epinephrine; Female; Formaldehyde; Glaucoma; Hypertension; Intraocular Pressure;

1969
The water-loading test in rabbits. A method to detect potential ocular hypotensive drugs.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1969, Volume: 82, Issue:3

    Topics: Acetazolamide; Animals; Atropine; Carbachol; Dichlorphenamide; Epinephrine; Glaucoma; Hexamethonium

1969
Dose response of intraocular pressures to single instillations of carbaminoylcholine chloride.
    Canadian journal of ophthalmology. Journal canadien d'ophtalmologie, 1966, Volume: 1, Issue:4

    Topics: Aged; Carbachol; Female; Glaucoma; Humans; Intraocular Pressure; Male; Middle Aged; Ophthalmic Solut

1966