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carbachol and Duodenal Ulcer

carbachol has been researched along with Duodenal Ulcer in 44 studies

Carbachol: A slowly hydrolyzed CHOLINERGIC AGONIST that acts at both MUSCARINIC RECEPTORS and NICOTINIC RECEPTORS.

Duodenal Ulcer: A PEPTIC ULCER located in the DUODENUM.

Research Excerpts

ExcerptRelevanceReference
"Duodenal ulcers were produced in rats by the subcutaneous infusion of carbachol and pentagastrin in combination."7.67[Carbachol-pentagastrin-induced duodenal ulcer in rats and its relation to gastric acid secretion]. ( Albrecht, R; Blech, W; Heinicke, G; Nowak, W, 1987)
"The effects of cimetidine, a new histamine H2-receptor antagonist, on the development of experimental gastric and duodenal ulcers were studied."7.65Effects of cimetidine, a histamine H2-receptor antagonist, on various experimental gastric and duodenal ulcers. ( Okabe, S; Takagi, K; Takeuchi, K; Urushidani, T, 1977)
"Dose-response studies of pentagastrin-stimulated secretion were performed in 6 unoperated duodenal ulcer patients."7.65Gastric secretory response to graded doses of pentagastrin alone or in combination with carbacholine in unoperated duodenal ulcer patients. ( Roland, M, 1975)
"The anti-ulcer and antisecretory properties of 3-(dibenz[b,e] oxepin - 11(6H)-ylidene)-N,N- dimethylpropylamine hydrochloride (doxepin) were investigated in a series of acute experiments in rats with gastric and duodenal ulcer."3.67Anti-ulcer and secretion-inhibitory properties of the tricyclic derivative doxepin in rats and dogs. ( Fleissig, W; Leitold, M; Merk, A, 1984)
"Duodenal ulcers were produced in rats by the subcutaneous infusion of carbachol and pentagastrin in combination."3.67[Carbachol-pentagastrin-induced duodenal ulcer in rats and its relation to gastric acid secretion]. ( Albrecht, R; Blech, W; Heinicke, G; Nowak, W, 1987)
"The gastric secretagogues, pentagastrin and carbachol, produced a 100% incidence of duodenal ulcers."3.66The effect of a parietal cell vagotomy and truncal vagotomy with and without drainage on duodenal ulcers in the rat. ( Crocket, A; Joffe, SN, 1981)
"A subthreshold dose of carbachol was used to test gallbladder reaction in a series of patients before operation, after truncal vagotomy with antrectomy (TA) and after parietal cell vagotomy (PCV) because of duodenal ulcer."3.66Gallbladder contraction as a test for vagal innervation. ( van Kuijk, PJ, 1979)
"The effects of cimetidine, a new histamine H2-receptor antagonist, on the development of experimental gastric and duodenal ulcers were studied."3.65Effects of cimetidine, a histamine H2-receptor antagonist, on various experimental gastric and duodenal ulcers. ( Okabe, S; Takagi, K; Takeuchi, K; Urushidani, T, 1977)
"In 10 patients with duodenal ulcer gastric secretion was studied after graded doses of pentagastrin before and 3 months after truncal vagotomy and pyloroplasty."3.65A secretory and histological study of the stomach before and after truncal vagotomy and pyloroplasty in duodenal ulcer patients. ( Roland, M, 1976)
"Duodenal ulcers were produced in rats by the subcutaneous infusion for 6-48 hours of two gastric secretagogues in combination: pentagastrin (2 or 4 microgram kg-1 min-1) and carbachol (0-4 or 0-8 microgram kg-1 min-1)."3.65Secretagogue-produced duodenal ulcers in the rat. ( Baron, JH; Barros D'sa, AA; Gaskin, RJ; Joffe, SN, 1977)
"Gastric secretion was stimulated by intravenous infusion of 15 mug/kg/hr of pentagastrin before and 10 and 90 days after proximal gastric vagotomy in 16 duodenal ulcer patients."3.65Decrease in gastric secretion during the first three months after proximal gastric vagotomy in duodenal ulcer patients. ( Berstad, A; Liavåg, I; Roland, M, 1975)
"Dose-response studies of pentagastrin-stimulated secretion were performed in 6 unoperated duodenal ulcer patients."3.65Gastric secretory response to graded doses of pentagastrin alone or in combination with carbacholine in unoperated duodenal ulcer patients. ( Roland, M, 1975)
"The gastric output of acid and pepsin in response to two doses of the cholinergic drug carbachol was measured before and two months after complete truncal vagotomy and pyloroplasty in eight patients with duodenal ulcer."3.65Effect of truncal vagotomy on acid and pepsin: response to a cholinergic drug in man. ( Cowley, DJ, 1972)
" Dose-response curves to cholecystokinin-octapeptide and carbachol were obtained."1.29Gallbladder motility in vitro in men with gallstones following Billroth II gastric resection. ( Caruso, ML; Lorusso, D; Maselli, MA; Pezzolla, F; Piepoli, AL, 1996)
"In this study duodenal ulcers have not only been produced in rats by secretagogues, but have also been observed to heal."1.25Natural history and morphology of secretagogue-induced duodenal ulcers in rats. ( Baron, JH; Barros D'sa, AA; Gad, A; Gaskin, RJ; Joffe, SN, 1975)

Research

Studies (44)

TimeframeStudies, this research(%)All Research%
pre-199040 (90.91)18.7374
1990's3 (6.82)18.2507
2000's1 (2.27)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
ARDEMAN, S1
CHANARIN, I1
DOYLE, JC1
Broomé, A2
Leth, R3
Elander, B3
Fellenius, E3
Olbe, L4
Haglund, U3
Rehnberg, O1
Leitold, M2
Fleissig, W1
Merk, A1
Joffe, SN10
Roberts, NB1
Taylor, WH1
Baron, JH6
Tani, S1
Yamazaki, H1
Muto, N1
Crocket, A1
Salim, AS2
Maselli, MA1
Pezzolla, F1
Piepoli, AL1
Caruso, ML1
Lorusso, D1
Padol, IT1
Moran, AP1
Hunt, RH1
Polak, JM2
Pallone, F1
Bloom, SR1
Gaskin, RJ4
Barros D'sa, AA5
Okabe, S1
Takeuchi, K1
Urushidani, T1
Takagi, K1
Robert, A6
Schultz, JR1
Nezamis, JE3
Lancaster, C2
Gaskin, R2
Melo, AA1
Gribble, JN1
Girvan, DP1
Csendes, A1
Oster, M1
Møller, J1
Brandsborg, O1
Brandsborg, M1
Amdrup, E1
Bapat, RD1
Rao, SS1
van Kuijk, PJ1
Roland, M6
Berstad, A3
Liavåg, I3
Gad, A1
Poulsen, SS1
D'Sa, AA1
Kolbasa, KP1
Olafsson, AS1
Lum, JT1
Forssell, H1
Albrecht, R2
Nowak, W2
Heinicke, G1
Blech, W1
Fleck, U1
Engelhorn, R1
Cowley, DJ2
Vernon, P1
Jones, T1
Glass, HI1
Cox, AG1
Dale, JE2
Stowe, DF2
Stout, TJ1

Reviews

1 review available for carbachol and Duodenal Ulcer

ArticleYear
Gastric antisecretory and antiulcer properties of PGE2, 15-methyl PGE2, and 16, 16-dimethyl PGE2. Intravenous, oral and intrajejunal administration.
    Gastroenterology, 1976, Volume: 70, Issue:3

    Topics: Administration, Oral; Animals; Carbachol; Cyclic AMP; Depression, Chemical; Dogs; Duodenal Ulcer; Fe

1976

Trials

2 trials available for carbachol and Duodenal Ulcer

ArticleYear
Reducing the recurrence rate of duodenal ulceration after highly selective vagotomy: a study in the rat and in man.
    The Journal of surgical research, 1993, Volume: 55, Issue:5

    Topics: Adult; Aged; Animals; Carbachol; Duodenal Ulcer; Gastric Acid; Humans; Male; Middle Aged; Nerve Rege

1993
Acid and pepsin secretion in duodenal ulcer patients in response to graded doses of pentagastrin or pentagastrin and carbacholine before and after proximal gastric vagotomy.
    Scandinavian journal of gastroenterology, 1974, Volume: 9, Issue:6

    Topics: Adult; Aged; Carbachol; Chronic Disease; Depression, Chemical; Dose-Response Relationship, Drug; Dru

1974

Other Studies

41 other studies available for carbachol and Duodenal Ulcer

ArticleYear
STUDIES ON SECRETION OF GASTRIC INTRINSIC FACTOR IN MAN.
    British medical journal, 1964, Sep-05, Volume: 2, Issue:5409

    Topics: Anemia; Anemia, Hypochromic; Anemia, Macrocytic; Carbachol; Celiac Disease; Cobalt Isotopes; Colonic

1964
Mechanism of the vagotomy-induced suppression of the maximal acid response to histamine in antrectomized duodenal ulcer patients.
    Scandinavian journal of gastroenterology, 1967, Volume: 2, Issue:4

    Topics: Anesthesia, Conduction; Carbachol; Duodenal Ulcer; Duodenum; Gastric Juice; Histamine; Humans; Pylor

1967
Effects of proximal gastric vagotomy and antrectomy on parietal cell function in humans.
    Gastroenterology, 1984, Volume: 87, Issue:6

    Topics: Adult; Aged; Aminopyrine; Bucladesine; Carbachol; Carbon Radioisotopes; Duodenal Ulcer; Follow-Up St

1984
The effects of secretagogues of isolated human gastric glands.
    Scandinavian journal of gastroenterology, 1982, Volume: 17, Issue:4

    Topics: 1-Methyl-3-isobutylxanthine; Adult; Aged; Aminopyrine; Bucladesine; Carbachol; Duodenal Ulcer; Gastr

1982
Anti-ulcer and secretion-inhibitory properties of the tricyclic derivative doxepin in rats and dogs.
    Arzneimittel-Forschung, 1984, Volume: 34, Issue:4

    Topics: Animals; Anti-Inflammatory Agents; Anti-Ulcer Agents; Benzodiazepinones; Carbachol; Cimetidine; Depr

1984
Exogenous and endogenous acid and pepsins in the pathogenesis of duodenal ulcers in the rat.
    Digestive diseases and sciences, 1980, Volume: 25, Issue:11

    Topics: Animals; Carbachol; Drug Synergism; Duodenal Ulcer; Gastric Juice; Hormones; Infusions, Parenteral;

1980
[Gastric emptying in chemical-administered and ulcerated rats].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 1983, Volume: 103, Issue:2

    Topics: Animals; Carbachol; Duodenal Ulcer; Gastric Emptying; Isoproterenol; Male; Rats; Rats, Inbred Strain

1983
The effect of a parietal cell vagotomy and truncal vagotomy with and without drainage on duodenal ulcers in the rat.
    Digestion, 1981, Volume: 22, Issue:1

    Topics: Animals; Carbachol; Drainage; Duodenal Ulcer; Male; Pentagastrin; Postoperative Complications; Rats;

1981
Gallbladder motility in vitro in men with gallstones following Billroth II gastric resection.
    Neurogastroenterology and motility, 1996, Volume: 8, Issue:1

    Topics: Aged; Aged, 80 and over; Carbachol; Cholecystectomy; Cholelithiasis; Duodenal Ulcer; Gallbladder; Hu

1996
Effect of purified lipopolysaccharides from strains of Helicobacter pylori and Helicobacter felis on acid secretion in mouse gastric glands in vitro.
    Infection and immunity, 2001, Volume: 69, Issue:6

    Topics: Animals; Carbachol; Dinoprostone; Disease Models, Animal; Duodenal Ulcer; Female; Gastric Acid; Gast

2001
Gastrin, antral g cells, and gastric acid in secretagogue-induced and antihistamine-inhibited duodenal ulcers.
    Scandinavian journal of gastroenterology, 1977, Volume: 12, Issue:1

    Topics: Animals; Carbachol; Duodenal Ulcer; Fluorescent Antibody Technique; Gastric Juice; Gastrins; Histami

1977
Effects of cimetidine, a histamine H2-receptor antagonist, on various experimental gastric and duodenal ulcers.
    The American journal of digestive diseases, 1977, Volume: 22, Issue:8

    Topics: Administration, Oral; Animals; Aspirin; Carbachol; Depression, Chemical; Disease Models, Animal; Duo

1977
Proceedings: Secretagogue-produced duodenal ulcers in the rat and their prevention by the gastric secretory inhibitor UK 9040.
    The British journal of surgery, 1975, Volume: 62, Issue:2

    Topics: Animals; Carbachol; Disease Models, Animal; Duodenal Ulcer; Gastric Mucosa; Histamine H1 Antagonists

1975
The effect of extrinsic denervation of the lower part of the esophagus on resting and cholinergic stimulated gastroesophageal sphincter in man.
    Surgery, gynecology & obstetrics, 1979, Volume: 148, Issue:3

    Topics: Adult; Aged; Carbachol; Denervation; Duodenal Ulcer; Esophagogastric Junction; Esophagus; Female; Hu

1979
The temporary effect of proximal gastric vagotomy on experimental duodenal ulcers and gastric secretion.
    The British journal of surgery, 1979, Volume: 66, Issue:4

    Topics: Animals; Carbachol; Duodenal Ulcer; Gastric Acidity Determination; Gastric Juice; Gastric Mucosa; Ma

1979
Histological grading and sequential morphological changes during the production of acute duodenal ulcers.
    British journal of experimental pathology, 1979, Volume: 60, Issue:4

    Topics: Acute Disease; Animals; Carbachol; Duodenal Ulcer; Intestinal Mucosa; Male; Necrosis; Pentagastrin;

1979
Gallbladder contraction as a test for vagal innervation.
    Diagnostic imaging, 1979, Volume: 48, Issue:6

    Topics: Carbachol; Cholecystography; Cholecystokinin; Duodenal Ulcer; Gallbladder; Humans; Pyloric Antrum; V

1979
A secretory and histological study of the stomach before and after truncal vagotomy and pyloroplasty in duodenal ulcer patients.
    Scandinavian journal of gastroenterology, 1976, Volume: 11, Issue:1

    Topics: Adult; Aged; Carbachol; Duodenal Ulcer; Gastric Juice; Gastric Mucosa; Gastritis; Humans; Male; Midd

1976
Secretagogue-produced duodenal ulcers in the rat.
    The British journal of surgery, 1977, Volume: 64, Issue:3

    Topics: Animals; Carbachol; Duodenal Ulcer; Pentagastrin; Peptic Ulcer Hemorrhage; Peptic Ulcer Perforation;

1977
Effect of proximal gastric vagotomy on gastric secretion.
    Scandinavian journal of gastroenterology. Supplement, 1976, Volume: 42

    Topics: Carbachol; Duodenal Ulcer; Gastric Juice; Gastric Mucosa; Humans; Pentagastrin; Secretory Rate; Vago

1976
Effect of urecholine and carbacholine on pentagastrin-stimulated gastric secretion after proximal gastric vagotomy in duodenal ulcer patients;.
    Scandinavian journal of gastroenterology, 1975, Volume: 10, Issue:3

    Topics: Adult; Bethanechol Compounds; Carbachol; Duodenal Ulcer; Gastric Juice; Humans; Male; Middle Aged; P

1975
Decrease in gastric secretion during the first three months after proximal gastric vagotomy in duodenal ulcer patients.
    Scandinavian journal of gastroenterology, 1975, Volume: 10, Issue:4

    Topics: Adult; Carbachol; Duodenal Ulcer; Female; Gastrectomy; Gastric Juice; Humans; Male; Middle Aged; Pen

1975
Gastric secretory response to graded doses of pentagastrin alone or in combination with carbacholine in unoperated duodenal ulcer patients.
    Scandinavian journal of gastroenterology, 1975, Volume: 10, Issue:6

    Topics: Adult; Aged; Carbachol; Dose-Response Relationship, Drug; Duodenal Ulcer; Gastric Juice; Gastric Muc

1975
Proceedings: Gastrin, G cells, and gastric acid in rats with secretagogue-produced and anti-secretagogue-inhibited duodenal ulcers.
    Gut, 1975, Volume: 16, Issue:5

    Topics: Animals; Carbachol; Duodenal Ulcer; Gastric Mucosa; Gastrins; Pentagastrin; Pyrrolidines; Rats; Thio

1975
Natural history and morphology of secretagogue-induced duodenal ulcers in rats.
    Gastroenterology, 1975, Volume: 69, Issue:4

    Topics: Animals; Carbachol; Disease Models, Animal; Duodenal Ulcer; Intestinal Mucosa; Male; Pentagastrin; R

1975
Letter: Duodenal ulcer in rats.
    Gastroenterology, 1976, Volume: 70, Issue:3

    Topics: Animals; Carbachol; Duodenal Ulcer; Pentagastrin; Rats

1976
Prevention of secretagogue-induced ulcers in the rat.
    Gastroenterology, 1976, Volume: 70, Issue:5 PT.1

    Topics: Animals; Carbachol; Dose-Response Relationship, Drug; Duodenal Ulcer; Gastric Juice; Histamine; Male

1976
The significance of removing oxygen-derived free radicals in the treatment of acute and chronic duodenal ulceration in the rat.
    The Journal of pharmacy and pharmacology, 1990, Volume: 42, Issue:1

    Topics: Allopurinol; Animals; Anti-Ulcer Agents; Carbachol; Cysteine; Dimethyl Sulfoxide; Duodenal Ulcer; Fe

1990
Role of endogenous prostaglandins in duodenal ulcer formation.
    Advances in prostaglandin, thromboxane, and leukotriene research, 1987, Volume: 17A

    Topics: 16,16-Dimethylprostaglandin E2; Animals; Carbachol; Dinoprostone; Duodenal Ulcer; Female; Gastric Ju

1987
Acid secretion in isolated gastric glands from healthy subjects and ulcer patients.
    Scandinavian journal of gastroenterology, 1985, Volume: 20, Issue:5

    Topics: Adult; Aged; Aminopyrine; Carbachol; Cyclic AMP; Duodenal Ulcer; Female; Gastric Acid; Histamine; Hu

1985
Studies on gastric bicarbonate secretion in man.
    Acta chirurgica Scandinavica. Supplementum, 1987, Volume: 540

    Topics: 16,16-Dimethylprostaglandin E2; Adult; Bicarbonates; Carbachol; Duodenal Ulcer; Female; Gastric Juic

1987
[Carbachol-pentagastrin-induced duodenal ulcer in rats and its relation to gastric acid secretion].
    Zeitschrift fur experimentelle Chirurgie, Transplantation, und kunstliche Organe : Organ der Sektion Experimentelle Chirurgie der Gesellschaft fur Chirurgie der DDR, 1987, Volume: 20, Issue:1

    Topics: Animals; Atropine; Carbachol; Duodenal Ulcer; Female; Gastric Acid; Gastric Mucosa; Kinetics; Pentag

1987
[Does extensive small intestine resection prevent experimentally induced duodenal ulcers? A study on rats].
    Zeitschrift fur experimentelle Chirurgie, Transplantation, und kunstliche Organe : Organ der Sektion Experimentelle Chirurgie der Gesellschaft fur Chirurgie der DDR, 1987, Volume: 20, Issue:1

    Topics: Animals; Carbachol; Duodenal Ulcer; Female; Gastric Acid; Intestine, Small; Pentagastrin; Rats; Rats

1987
Proceedings: Pharmacological examinations by an ulcus inhibiting agent (L-S 519).
    Naunyn-Schmiedeberg's archives of pharmacology, 1974, Volume: 282, Issue:Suppl

    Topics: Animals; Benzodiazepinones; Carbachol; Cysteamine; Dose-Response Relationship, Drug; Duodenal Ulcer;

1974
Effect of truncal vagotomy on acid and pepsin: response to a cholinergic drug in man.
    Gut, 1972, Volume: 13, Issue:2

    Topics: Carbachol; Duodenal Ulcer; Fluoroscopy; Gastric Juice; Humans; Injections, Subcutaneous; Male; Pepsi

1972
Potentiation, by nicotine, of duodenal ulcers in the rat.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1972, Volume: 139, Issue:1

    Topics: Animals; Carbachol; Drug Antagonism; Drug Combinations; Drug Synergism; Duodenal Ulcer; Female; Gast

1972
Gastric emptying of solid meals after truncal vagotomy and pyloroplasty in human subjects.
    Gut, 1972, Volume: 13, Issue:3

    Topics: Carbachol; Cesium Isotopes; Diet; Duodenal Ulcer; Food; Gastrointestinal Motility; Humans; Postgastr

1972
Role of gastric acid in the development of duodenal ulcers in the rat.
    Digestion, 1972, Volume: 6, Issue:1

    Topics: Animals; Bicarbonates; Carbachol; Duodenal Ulcer; Female; Gastric Acidity Determination; Gastric Jui

1972
Studies on the mechanism of te antrectomy-inced suppression of the maximal acid response to histamine in duodenal ulcer patients.
    Scandinavian journal of gastroenterology, 1969, Volume: 4, Issue:3

    Topics: Carbachol; Duodenal Ulcer; Gastrectomy; Gastric Acidity Determination; Gastric Juice; Gastrins; Hist

1969
Production by secretagogues of duodenal ulcers in the rat.
    Gastroenterology, 1970, Volume: 59, Issue:1

    Topics: Animals; Carbachol; Drug Synergism; Duodenal Ulcer; Female; Gastric Juice; Gastrins; Histamine; Inje

1970
Prevention of duodenal ulcers by administration of prostaglandin E 2 (PGE 2 ).
    Scandinavian journal of gastroenterology, 1971, Volume: 6, Issue:4

    Topics: Animals; Carbachol; Duodenal Ulcer; Female; Gastrins; Histamine; Peptides; Prostaglandins; Rats; Tim

1971