carbachol has been researched along with Disease Models, Animal in 221 studies
Carbachol: A slowly hydrolyzed CHOLINERGIC AGONIST that acts at both MUSCARINIC RECEPTORS and NICOTINIC RECEPTORS.
Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We have investigated the effects of cannabinoids on tracheal hyperreactivity and airway inflammation in dinitrofluorobenzene (DNFB)-induced experimental non-atopic asthma in mice." | 7.83 | The effect of cannabinoids on dinitrofluorobenzene-induced experimental asthma in mice. ( Bozkurt, TE; Durlu-Kandilci, NT; Kaya, Y; Onder, S; Sahin-Erdemli, I, 2016) |
| "To investigate a possible relation between hypercholesterolemia and detrusor smooth muscle function, we studied the contractile response to potassium challenge, carbachol (CCh), and the components of CCh-induced contractile mechanism in high-cholesterol diet-fed rats." | 7.78 | The effect of hypercholesterolemia on carbachol-induced contractions of the detrusor smooth muscle in rats: increased role of L-type Ca2+ channels. ( Balkanci, ZD; Bayrak, S; Erdem, A; Karabulut, I; Karaismailoğlu, S; Pehlivanoğlu, B, 2012) |
| "Carbachol-induced contraction of the rat colon is impaired in rats with trinitrobenzene sulfonic acid (TNBS)-induced colitis." | 7.77 | Colonic inflammation increases the contribution of muscarinic M2 receptors to carbachol-induced contraction of the rat colon. ( Jragh, DM; Khan, I; Oriowo, MA, 2011) |
| " In this study we examine the expression and function of FIZZ1 in an ovalbumin mouse model of asthma." | 7.76 | FIZZ1 potentiates the carbachol-induced tracheal smooth muscle contraction. ( Bowman, MR; Chen, H; Jacobson, BA; Mason, L; Wolf, SF, 2010) |
| "To investigate the effect of curcumin on colitis-induced reduction of carbachol-induced contraction in colon segments from rats treated with trinitrobenzenesulphonic acid." | 7.75 | Curcumin reverses attenuated carbachol-induced contraction of the colon in a rat model of colitis. ( Khan, I; Lubbad, AS; Oriowo, MA, 2009) |
| "To investigate the effects of carbachol (CAR) on pulmonary vascular permeability and pulmonary water content during oral fluid resuscitation of burn shock." | 7.75 | [The effect of carbachol on pulmonary vascular permeability and lung water content during oral fluid resuscitation of burn shock induced by a 50% total body surface area full-thickness flame injury in dogs]. ( Bao, CM; Chen, JW; Hu, S; Sheng, ZY, 2009) |
| "To investigate the effect of carbachol (CAR) on visceral perfusion and lipid oxidation injury in rats with sepsis." | 7.75 | [The protective effects of carbachol on visceral ischemia-induced lipid peroxidation injury in rats with sepsis]. ( Bai, HY; Bao, CM; Hu, S; Zhang, LJ, 2009) |
| "Carbachol can lower the DC activity, suggesting that modulation of DC activity may lower extensive immune and inflammatory response in the early phases of sepsis." | 7.73 | [Effect of carbachol on dendritic cell function in the lipopolysaccharides induced murine sepsis model]. ( Hu, S; Lu, JY; Lü, Y; Tian, G; Wang, HW; Yang, Y, 2006) |
| "To evaluate the effect of cholinergic drug carbachol on apoptosis and expression of certain cytokines of peripheral blood lymphocytes and neutrophils in rats subjected to ischemia/reperfusion injury of the intestine." | 7.73 | [Effects of carbachol on apoptosis of peripheral white blood cells and expression of cytokines in rats suffering from gut ischemia/reperfusion injury]. ( Hu, S; Jiang, XG; Lu, Y; Sheng, ZY; Sun, D; Wang, HB, 2005) |
| "To study the effects of enteral administration of carbachol on organ dysfunction induced by partial ischemia/reperfusion injury to the intestine." | 7.73 | [Enteral administration of carbachol on systemic inflammatory response and multiple organ dysfunction induced by partial ischemia/reperfusion injury to the gut]. ( Bai, YM; Cao, WH; Hu, S; Lu, Y; Sheng, ZY; Sun, D, 2005) |
| "The role of indomethacin-induced peptic ulceration in gastric acid secretion was investigated using albino rats of Wistar strain in early, mid and late pregnancy." | 7.68 | Role of indomethacin-induced peptic ulceration in gastric acid secretion in pregnant rats. ( Bolarinwa, Y; Evbuomwan, MI, 1993) |
| "The chronically pilocarpine-treated rat has been proposed as an animal model for the disease cystic fibrosis, a generalized exocrinopathy." | 7.67 | The chronically pilocarpine-treated rat in the study of cystic fibrosis: investigations on submandibular gland and pancreas. ( Bardon, A; Ceder, O; Kuijpers, GA; Müller, RM; Roomans, GM, 1985) |
| "The effects of cimetidine, a new histamine H2-receptor antagonist, on the development of experimental gastric and duodenal ulcers were studied." | 7.65 | Effects of cimetidine, a histamine H2-receptor antagonist, on various experimental gastric and duodenal ulcers. ( Okabe, S; Takagi, K; Takeuchi, K; Urushidani, T, 1977) |
| "Agmatine has been reported to attenuate I/R injury of various organs." | 5.46 | Agmatine attenuates intestinal ischemia and reperfusion injury by reducing oxidative stress and inflammatory reaction in rats. ( Araslı, M; Barut, F; Ozacmak, HS; Ozacmak, VH; Turan, I, 2017) |
| "Subarachnoid hemorrhage stimulates apoptosis of the rabbit bladder and impairs the contractile response of the rabbit bladder to carbachol." | 3.96 | Hyperbaric oxygen therapy prevents subarachnoid hemorrhage-induced apoptosis and impaired contractility of the rabbit bladder. ( Cadirci, S; Celik, O; Cevik, O; Oroglu, B; Sekerci, CA; Sener, G; Tarcan, T; Tinay, I, 2020) |
| "Chemical stimulation of the lateral hypothalamus (LH) with carbachol induces antinociception which is antagonized by blockade of orexin receptors in some pain modulatory sites in the tail-flick test." | 3.83 | Functional interaction between orexin-1 and CB1 receptors in the periaqueductal gray matter during antinociception induced by chemical stimulation of the lateral hypothalamus in rats. ( Esmaeili, MH; Ezzatpanah, S; Haghparast, A; Reisi, Z, 2016) |
| " We have investigated the effects of cannabinoids on tracheal hyperreactivity and airway inflammation in dinitrofluorobenzene (DNFB)-induced experimental non-atopic asthma in mice." | 3.83 | The effect of cannabinoids on dinitrofluorobenzene-induced experimental asthma in mice. ( Bozkurt, TE; Durlu-Kandilci, NT; Kaya, Y; Onder, S; Sahin-Erdemli, I, 2016) |
| " A preventive effect on ovalbumin (OVA)-induced bronchospasm was observed in sensitized guinea pigs for each androgen." | 3.80 | Androgens are bronchoactive drugs that act by relaxing airway smooth muscle and preventing bronchospasm. ( Chávez, J; Espinoza, J; Flores-Soto, E; Montaño, LM; Perusquía, M, 2014) |
| "To investigate a possible relation between hypercholesterolemia and detrusor smooth muscle function, we studied the contractile response to potassium challenge, carbachol (CCh), and the components of CCh-induced contractile mechanism in high-cholesterol diet-fed rats." | 3.78 | The effect of hypercholesterolemia on carbachol-induced contractions of the detrusor smooth muscle in rats: increased role of L-type Ca2+ channels. ( Balkanci, ZD; Bayrak, S; Erdem, A; Karabulut, I; Karaismailoğlu, S; Pehlivanoğlu, B, 2012) |
| " Metformin treatment improved the insulin sensitivity, and normalized the in vitro bladder hypercontractility and cystometric dysfunction in obese mice." | 3.78 | Role of PKC and CaV1.2 in detrusor overactivity in a model of obesity associated with insulin resistance in mice. ( Anhê, GF; Antunes, E; Calixto, MC; De Nucci, G; Grant, AD; Leiria, LO; Lintomen, L; Mónica, FZ; Sollon, C; Zanesco, A, 2012) |
| "In a rat model of experimental periodontitis it was investigated whether the presence of the inflammatory disease induced changes in carbachol-induced fluid secretion in parotid glands, by monitoring potassium release." | 3.78 | Influence of experimental periodontitis on cholinergic stimulation of K⁺ release in rat parotid glands. ( Busch, L; Miozza, VA; Sánchez, GA, 2012) |
| "Carbachol-induced contraction of the rat colon is impaired in rats with trinitrobenzene sulfonic acid (TNBS)-induced colitis." | 3.77 | Colonic inflammation increases the contribution of muscarinic M2 receptors to carbachol-induced contraction of the rat colon. ( Jragh, DM; Khan, I; Oriowo, MA, 2011) |
| " In this study we examine the expression and function of FIZZ1 in an ovalbumin mouse model of asthma." | 3.76 | FIZZ1 potentiates the carbachol-induced tracheal smooth muscle contraction. ( Bowman, MR; Chen, H; Jacobson, BA; Mason, L; Wolf, SF, 2010) |
| "Colitis was induced in rats by 2,4-dinitrobenzenesulfonic acid." | 3.76 | Control of enteric neuromuscular functions by purinergic A(3) receptors in normal rat distal colon and experimental bowel inflammation. ( Antonioli, L; Awwad, O; Bin, A; Blandizzi, C; Castagliuolo, I; Colucci, R; Fornai, M; Gaion, RM; Ghisu, N; Giron, MC; Tuccori, M; Zoppellaro, C, 2010) |
| "Recently we reported that intrathalamic microinjection of carbachol triggers generalized convulsive seizures (GCS) followed by severe inflammatory response including edema, microhemorrhages, and subsequent degeneration of amygdaloallocortical area." | 3.76 | Aggravation of seizure-associated microvascular injuries by ibuprofen may involve multiple pathways. ( Mraovitch, S; Régnier, A; Vicaut, E, 2010) |
| "To investigate the effect of carbachol (CAR) on visceral perfusion and lipid oxidation injury in rats with sepsis." | 3.75 | [The protective effects of carbachol on visceral ischemia-induced lipid peroxidation injury in rats with sepsis]. ( Bai, HY; Bao, CM; Hu, S; Zhang, LJ, 2009) |
| "To investigate the effect of curcumin on colitis-induced reduction of carbachol-induced contraction in colon segments from rats treated with trinitrobenzenesulphonic acid." | 3.75 | Curcumin reverses attenuated carbachol-induced contraction of the colon in a rat model of colitis. ( Khan, I; Lubbad, AS; Oriowo, MA, 2009) |
| "To investigate the effects of carbachol (CAR) on pulmonary vascular permeability and pulmonary water content during oral fluid resuscitation of burn shock." | 3.75 | [The effect of carbachol on pulmonary vascular permeability and lung water content during oral fluid resuscitation of burn shock induced by a 50% total body surface area full-thickness flame injury in dogs]. ( Bao, CM; Chen, JW; Hu, S; Sheng, ZY, 2009) |
| " ANP did not affect receptor-dependent and receptor-independent gastric muscle contractions except the contractions to substance P, which were slightly inhibited." | 3.73 | Regional differences in gastrointestinal motility disturbances during acute necrotising pancreatitis. ( De Man, JG; De Winter, BY; Herman, AG; Pelckmans, PA; Seerden, TC; Van Den Bossche, RM, 2005) |
| "To evaluate the effect of cholinergic drug carbachol on apoptosis and expression of certain cytokines of peripheral blood lymphocytes and neutrophils in rats subjected to ischemia/reperfusion injury of the intestine." | 3.73 | [Effects of carbachol on apoptosis of peripheral white blood cells and expression of cytokines in rats suffering from gut ischemia/reperfusion injury]. ( Hu, S; Jiang, XG; Lu, Y; Sheng, ZY; Sun, D; Wang, HB, 2005) |
| "Enteral administration of Carbachol can increase the blood flow of intestine mucosa, help to improve the movement, absorption and barrier functions of intestine, and ameliorate intestinal dysfunction in patients with severe burns." | 3.73 | [Influence of carbachol on intestinal dysfunction after traumatic or burn injury]. ( Cao, WH; Chai, JK; Hu, S; Sheng, ZY; Sun, TJ; Yang, HM; Zou, XF, 2006) |
| "To study the effects of enteral administration of carbachol on organ dysfunction induced by partial ischemia/reperfusion injury to the intestine." | 3.73 | [Enteral administration of carbachol on systemic inflammatory response and multiple organ dysfunction induced by partial ischemia/reperfusion injury to the gut]. ( Bai, YM; Cao, WH; Hu, S; Lu, Y; Sheng, ZY; Sun, D, 2005) |
| "Carbachol can lower the DC activity, suggesting that modulation of DC activity may lower extensive immune and inflammatory response in the early phases of sepsis." | 3.73 | [Effect of carbachol on dendritic cell function in the lipopolysaccharides induced murine sepsis model]. ( Hu, S; Lu, JY; Lü, Y; Tian, G; Wang, HW; Yang, Y, 2006) |
| " Smooth muscle relaxation was obtained by salbutamol and l-phenylephrine, whereas contraction was achieved by carbachol and 1-(3-chlorophenyl)-biguanide." | 3.72 | Effect of pharmacologically induced smooth muscle activation on permeability in murine colitis. ( Garrelds, IM; Meijssen, MA; van Meeteren, ME; Zijlstra, FJ, 2003) |
| "The results demonstrate that the rate of contractile failure induced by in vitro ischemia is greater than that induced by in vitro hypoxia, and that the contractile response to FS is significantly more sensitive to both hypoxia and in vitro ischemia than is the contractile response to either carbachol or KCl." | 3.70 | Effect of repetitive stimulation on the contractile response of rabbit urinary bladder subjected to in vitro hypoxia or in vitro ischemia followed by reoxygenation. ( Horan, P; Levin, RM; Liu, SP; Ohnishi, N, 1998) |
| "Chronic reserpine treatment of animals, an experimental model for cystic fibrosis (CF), results in generalized exocrinopathy, impaired secretion, and decreased pancreatic content of amylase." | 3.68 | Alterations of amylase secretion in the chronically reserpinized rat: an acetylcholine-mediated phenomenon. ( Benrezzak, O; Bérubé, FL; Morisset, J, 1991) |
| "The role of indomethacin-induced peptic ulceration in gastric acid secretion was investigated using albino rats of Wistar strain in early, mid and late pregnancy." | 3.68 | Role of indomethacin-induced peptic ulceration in gastric acid secretion in pregnant rats. ( Bolarinwa, Y; Evbuomwan, MI, 1993) |
| "The chronically pilocarpine-treated rat has been proposed as an animal model for the disease cystic fibrosis, a generalized exocrinopathy." | 3.67 | The chronically pilocarpine-treated rat in the study of cystic fibrosis: investigations on submandibular gland and pancreas. ( Bardon, A; Ceder, O; Kuijpers, GA; Müller, RM; Roomans, GM, 1985) |
| "The effects of cimetidine, a new histamine H2-receptor antagonist, on the development of experimental gastric and duodenal ulcers were studied." | 3.65 | Effects of cimetidine, a histamine H2-receptor antagonist, on various experimental gastric and duodenal ulcers. ( Okabe, S; Takagi, K; Takeuchi, K; Urushidani, T, 1977) |
| "However, it failed to affect left ventricular hypertrophy and even aggravated the impaired positive and negative lusitropic effects elicited by isoprenaline and carbachol, respectively." | 1.62 | Chronic cannabidiol treatment reduces the carbachol-induced coronary constriction and left ventricular cardiomyocyte width of the isolated hypertensive rat heart. ( Gajo, B; Harasim-Symbor, E; Kasacka, I; Malinowska, B; Pędzińska-Betiuk, A; Schlicker, E; Toczek, M; Weresa, J, 2021) |
| "Mechanical allodynia and thermal hyperalgesia were evaluated using von Frey filaments and a thermal stimulus." | 1.56 | Chemical stimulation of the lateral hypothalamus induces antiallodynic and anti-thermal hyperalgesic effects in animal model of neuropathic pain: Involvement of orexin receptors in the spinal cord. ( Haghparast, A; Kashfi, K; Manaheji, H; Salehi, S, 2020) |
| "In conclusion, HGprt deficiency in mice is associated with a decrease in colon contractility, not dependent upon reduction of acetylcholine release from the myenteric plexus or hyperactivity of inhibitory signalling." | 1.48 | Altered gastrointestinal motility in an animal model of Lesch-Nyhan disease. ( Belluardo, N; Caciagli, F; Ciccarelli, R; Condorelli, DF; Di Iorio, P; Frinchi, M; Jinnah, HA; Mudò, G; Mulè, F; Nuzzo, D; Serio, R; Zizzo, MG, 2018) |
| "Agmatine has been reported to attenuate I/R injury of various organs." | 1.46 | Agmatine attenuates intestinal ischemia and reperfusion injury by reducing oxidative stress and inflammatory reaction in rats. ( Araslı, M; Barut, F; Ozacmak, HS; Ozacmak, VH; Turan, I, 2017) |
| "Carbachol was a chemoattractant for microglia and decreased their phagocytic activity." | 1.43 | The subpopulation of microglia expressing functional muscarinic acetylcholine receptors expands in stroke and Alzheimer's disease. ( Endres, M; Kettenmann, H; Kronenberg, G; Matyash, V; Meier, MA; Pannell, M; Prinz, V; Szulzewsky, F; Waiczies, S; Wolf, SA, 2016) |
| "Neurochemical alterations in Alzheimer's disease (AD) include cholinergic neuronal loss in the nucleus basalis of Meynert (nbM) and a decrease in densities of the M2 muscarinic receptor subtype in areas related to learning and memory." | 1.43 | Activity of muscarinic, galanin and cannabinoid receptors in the prodromal and advanced stages in the triple transgenic mice model of Alzheimer's disease. ( Giménez-Llort, L; LaFerla, FM; Lombardero, L; Manuel, I; Rodríguez-Puertas, R, 2016) |
| "Nitrofen-treated lungs exhibited an increased number of proliferating Sox9-positive distal epithelial progenitor cells, which were decreased and normalized by treatment with carbachol." | 1.42 | Defective parasympathetic innervation is associated with airway branching abnormalities in experimental CDH. ( Gittes, GK; Potoka, DA; Rhodes, J; Saxena, D; Zhang, G, 2015) |
| "The study of late-onset/age-related Alzheimer's disease (AD)(sporadic AD, 95% of AD cases) has been hampered by a paucity of animal models." | 1.42 | Characterization of Aldh2 (-/-) mice as an age-related model of cognitive impairment and Alzheimer's disease. ( Andrew, RD; Bennett, BM; D'Souza, Y; Elharram, A; Soon-Shiong, R, 2015) |
| "We used the Akita mouse model of type 1 diabetes to study the effects of the parasympathetic agonist carbachol (CCh) on SAN function using intracardiac programmed stimulation, high resolution optical mapping and patch-clamping of SAN myocytes." | 1.42 | Altered parasympathetic nervous system regulation of the sinoatrial node in Akita diabetic mice. ( Azer, J; Bogachev, O; Egom, EE; Jansen, HJ; Krishnaswamy, PS; Mackasey, M; Moghtadaei, M; Robbins, C; Rose, RA, 2015) |
| "Senicapoc-treated sheep also demonstrated reduced airway hyperresponsiveness, requiring a significantly higher dose of carbachol to increase resistance by 100% compared to allergen-challenged vehicle-control sheep (20±5 vs." | 1.39 | K(Ca)3.1 channel-blockade attenuates airway pathophysiology in a sheep model of chronic asthma. ( Barcham, G; Barker, D; Bradding, P; Castle, N; Koumoundouros, E; Snibson, K; Sum, G; Van Der Velden, J; Wulff, H, 2013) |
| "Partial bladder outlet obstruction (PBOO), a common urologic pathology mostly caused by benign prostatic hyperplasia, can coexist in 40-45% of patients with overactive bladder (OAB) and is associated with detrusor overactivity (DO)." | 1.37 | Blebbistain, a myosin II inhibitor, as a novel strategy to regulate detrusor contractility in a rat model of partial bladder outlet obstruction. ( DiSanto, ME; Seftel, A; Zhang, X, 2011) |
| "Alcohol abuse is a leading cause of pancreatitis, accounting for 30% of acute cases and 70-90% of chronic cases, yet the mechanisms leading to alcohol-associated pancreatic injury are unclear." | 1.37 | Ethanol enhances carbachol-induced protease activation and accelerates Ca2+ waves in isolated rat pancreatic acini. ( Ahmad, A; Husain, SZ; Luo, Y; Mahmood, SM; Muili, K; Orabi, AI; Reed, A; Shah, AU, 2011) |
| "After laser treatment, intraocular pressure (IOP) was elevated 1." | 1.36 | Altered calcium signaling in an experimental model of glaucoma. ( Akerman, KE; Kaarniranta, K; Kalesnykas, G; Larsson, KP; Niittykoski, M; Uusitalo, H, 2010) |
| "It is suggested that chronic hyperlipidemia contributes to the bladder dysfunction." | 1.36 | The effects of chronic hyperlipidemia on bladder function in myocardial infarction-prone Watanabe heritable hyperlipidemic (WHHLMI) rabbits. ( Masunaga, K; Nagata, T; Satoji, Y; Shiomi, M; Yoshida, M, 2010) |
| "In this mouse model of food allergy, we demonstrated a decreased response to a muscarinic agonist, and increased levels of proinflammatory IL-6 and Th2-related IL-4, but not Th1-related IFN-gamma mRNAs in jejunum." | 1.35 | Food allergy alters jejunal circular muscle contractility and induces local inflammatory cytokine expression in a mouse model. ( Berstad, A; Eklund, KK; Kovanen, PT; Lappalainen, J; Lin, AH; Rita, H; Vaali, K; Valeur, J, 2009) |
| "Celiac disease is a gluten intolerance caused by a T-cell response against human leukocyte antigen (HLA)-DQ2 and DQ8-bound gluten peptides." | 1.35 | Gliadin-dependent neuromuscular and epithelial secretory responses in gluten-sensitive HLA-DQ8 transgenic mice. ( Blennerhassett, PA; David, CS; Huang, X; Lu, J; McKay, DM; Murray, JA; Natividad, J; Verdu, EF, 2008) |
| " In the first 8 hours post burn, intestinal absorption rate of water and Na+, intestinal mucosa blood flow (IBF), the plasma volume (PV) and plasma concentration of Na+ were continuously determined without anesthesia." | 1.35 | [Effect of carbachol on intestinal mucosa blood flow and absorption rate of glucose-electrolyte solution during enteral resuscitation for 50% total body surface area full-thickness burn injury in dog]. ( Bao, CM; Che, JW; Du, Y; Geng, SJ; Hu, S; Sheng, ZY; Tian, YJ; Wang, L; Wu, J, 2008) |
| "Colitis was induced in Sprague-Dawley male rats by intra-colonic instillation of trinitrobenzenesulphonic acid (TNBS; 40 mg/rat in 50 ethanol)." | 1.33 | Mechanism underlying the reversal of contractility dysfunction in experimental colitis by cyclooxygenase-2 inhibition. ( Khan, I; Oriowo, MA, 2006) |
| "Tegaserod treatment, which did not affect cholinergic contractions of tissues from low cholesterol fed animals, abrogated the increase caused by the high cholesterol diet." | 1.33 | Increased cholinergic contractions of jejunal smooth muscle caused by a high cholesterol diet are prevented by the 5-HT4 agonist--tegaserod. ( Mathison, R; Shaffer, E, 2006) |
| "Hypothyroidism has been reported to occur in 6% of impotent men." | 1.33 | Effect of hypothyroidism on the nitrergic relaxant responses of corpus cavernosal smooth muscle in rabbits. ( Bagcivan, I; Kaya, K; Kilicarslan, H; Sarac, B; Yildirim, MK; Yildirim, S, 2006) |
| "Acute gastroenteritis is a strong risk factor for the development of irritable bowel syndrome (IBS)." | 1.33 | Mechanisms underlying the maintenance of muscle hypercontractility in a model of postinfective gut dysfunction. ( Akiho, H; Blennerhassett, P; Collins, SM; Deng, Y; Kanbayashi, H, 2005) |
| "Hypothyroidism has been reported to occur in 6% of impotent men." | 1.33 | Effect of hypothyroidism on the NO/cGMP pathway of corpus cavernosum in rabbits. ( Bagcivan, I; Kaya, T; Kilicarslan, H; Sarac, B; Yildirim, MK, 2006) |
| "Our results suggest that bladder outlet obstruction produces a muscle cell that develops higher levels of force but with greatly reduced cross bridge cycling rates." | 1.32 | Effect of partial outlet obstruction on rabbit urinary bladder smooth muscle function. ( Moreland, RS; Stanton, MC; Stein, R; Su, X; Zderic, S, 2003) |
| "Tachyarrhythmia was evoked in isolated rat right atria by trains of electric stimuli." | 1.32 | Cholinergic-adrenergic antagonism in the induction of tachyarrhythmia by electrical stimulation in isolated rat atria. ( Bassani, JW; Bassani, RA; Zafalon, N, 2004) |
| "Fragile X syndrome is an inherited cause of mental retardation." | 1.32 | Involvement of cholinergic and gabaergic systems in the fragile X knockout mice. ( Avoli, M; D'Antuono, M; Merlo, D, 2003) |
| "Right ventricular hypertrophy was increased by 51%, 93% and 55%, respectively, at 14 days." | 1.31 | Differences in time-related cardiopulmonary responses to hypoxia in three rat strains. ( Bochnowicz, S; Hart, T; Hay, DW; Louden, C; Luttmann, MA; Osborn, RR; Underwood, DC, 2000) |
| "Quercitrin is a flavonoid with antiinflammatory activity in experimental colitis, associated with an antioxidative action and amelioration of water absorption in vivo." | 1.31 | Effect of quercitrin on the early stages of hapten induced colonic inflammation in the rat. ( Gálvez, J; Sánchez de Medina, F; Vera, B; Zarzuelo, A, 2002) |
| "It has been proposed that migraine could result from a neurogenic inflammation of the dura mater." | 1.30 | Plasma protein extravasation induced in the rat dura mater by stimulation of the parasympathetic sphenopalatine ganglion. ( Aubineau, P; Delépine, L, 1997) |
| " A leftward shift in the carbachol dose-response curve indicated increased sensitivity to carbachol in Cd- and/or Sepretreated guinea pigs." | 1.30 | Guinea pig pulmonary mechanics: altered sensitivity to carbachol by cadmium and/or selenium. ( Bell, RR; Early, JL; Hammerbeck, DM; Nonavinakere, VK; Soliman, MR, 1998) |
| "Reserpine treatment resulted in altered enzyme secretion from rat pancreatic acini in response to carbamylcholine and secretin (1,2)." | 1.29 | Alterations of pancreatic amylase secretion in the reserpinized rat model of cystic fibrosis. Effects of cerulein and EGF. ( Benrezzak, O; Bérubé, FL; Morisset, J; Vanier, M, 1994) |
| "myo-Inositol uptake was restored to normal in a time-dependent manner during recovery of islets at 5." | 1.29 | Insulin secretion, myo-inositol transport, and Na(+)-K(+)-ATPase in glucose-desensitized rat islets. ( Laychock, SG; Xia, M, 1993) |
| "Mild bladder outlet obstruction was created in 42 New Zealand white rabbits by placing a 5-mm inner diameter polyethylene tube around the urethra." | 1.29 | Effects of mild bladder outlet obstruction on rabbit bladder structure and function. ( Kuo, HC, 1995) |
| ") did not bronchodilate but caused a parallel 7 fold rightward shift in the histamine dose-response curve." | 1.29 | Inhibition of bronchospasm and ozone-induced airway hyperresponsiveness in the guinea-pig by CDP840, a novel phosphodiesterase type 4 inhibitor. ( Gozzard, N; Higgs, G; Holbrook, M; Hughes, B; James, T, 1996) |
| "Acute edematous pancreatitis was produced in rats by subcutaneous administration of caerulein." | 1.28 | Prevention by prostaglandins of caerulein-induced pancreatitis in rats. ( Kolbasa, KP; Lancaster, C; Lum, JT; Nezamis, JE; Olafsson, AS; Robert, A, 1989) |
| "In this study duodenal ulcers have not only been produced in rats by secretagogues, but have also been observed to heal." | 1.25 | Natural history and morphology of secretagogue-induced duodenal ulcers in rats. ( Baron, JH; Barros D'sa, AA; Gad, A; Gaskin, RJ; Joffe, SN, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 30 (13.57) | 18.7374 |
| 1990's | 22 (9.95) | 18.2507 |
| 2000's | 89 (40.27) | 29.6817 |
| 2010's | 64 (28.96) | 24.3611 |
| 2020's | 16 (7.24) | 2.80 |
| Authors | Studies |
|---|---|
| Abrams, RPM | 1 |
| Yasgar, A | 1 |
| Teramoto, T | 1 |
| Lee, MH | 1 |
| Dorjsuren, D | 1 |
| Eastman, RT | 1 |
| Malik, N | 1 |
| Zakharov, AV | 1 |
| Li, W | 1 |
| Bachani, M | 1 |
| Brimacombe, K | 1 |
| Steiner, JP | 1 |
| Hall, MD | 1 |
| Balasubramanian, A | 1 |
| Jadhav, A | 1 |
| Padmanabhan, R | 1 |
| Simeonov, A | 1 |
| Nath, A | 1 |
| Fu, R | 2 |
| Janga, S | 1 |
| Edman, MC | 3 |
| Hamm-Alvarez, SF | 3 |
| Joo, NS | 1 |
| Cho, HJ | 1 |
| Shinbashi, M | 1 |
| Choi, JY | 1 |
| Milla, CE | 1 |
| Engelhardt, JF | 1 |
| Wine, JJ | 1 |
| Ye, L | 1 |
| Zeng, Q | 1 |
| Ling, M | 1 |
| Ma, R | 1 |
| Chen, H | 2 |
| Lin, F | 1 |
| Li, Z | 1 |
| Pan, L | 1 |
| Logantha, SJRJ | 1 |
| Kharche, SR | 1 |
| Zhang, Y | 3 |
| Atkinson, AJ | 1 |
| Hao, G | 1 |
| Boyett, MR | 1 |
| Dobrzynski, H | 1 |
| Zendehdel, M | 1 |
| Lankarani Mohajer, L | 1 |
| Hassanpour, S | 1 |
| Wang, KL | 1 |
| Hsia, SM | 1 |
| Wang, PS | 1 |
| Lin, PH | 1 |
| Salehi, S | 1 |
| Kashfi, K | 1 |
| Manaheji, H | 1 |
| Haghparast, A | 6 |
| Luan, X | 1 |
| Tam, JS | 1 |
| Jagadeeshan, S | 1 |
| Grishchenko, N | 1 |
| Hassan, N | 1 |
| Gioino, P | 1 |
| Shipley, AM | 1 |
| Machen, TE | 1 |
| Ianowski, JP | 1 |
| Tinay, I | 2 |
| Celik, O | 1 |
| Sekerci, CA | 1 |
| Cadirci, S | 1 |
| Cevik, O | 1 |
| Oroglu, B | 1 |
| Sener, G | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Extracoporeal Shock Wave Therapy (ESWT) for the Treatment of Detrusor Underactivity/ Underactive Bladder (DU/UAB) - a Single Center, Randomized, Double-blind, Placebo-controlled, Prospective Study[NCT04161183] | 11 participants (Actual) | Interventional | 2019-10-15 | Completed | |||
| Can Acupoint Low Intensity Shockwave Therapy Improve Bladder Voiding Efficiency: A Pilot Study.[NCT06020963] | 100 participants (Anticipated) | Interventional | 2023-08-11 | Recruiting | |||
| Effectiveness of Oral Boldo in Improving Urinary Symptoms and Body Stability in Women Diagnosed With Overactive Bladder[NCT06162065] | Phase 1 | 10 participants (Anticipated) | Interventional | 2023-11-01 | Enrolling by invitation | ||
| Crossover Trial of Gluten and Gluten With Amylase-trypsin Inhibitors as Triggers of Gastrointestinal Symptoms in Patients With Irritable Bowel Syndrome[NCT03664531] | 34 participants (Anticipated) | Interventional | 2019-01-01 | Recruiting | |||
| Circumferential vs Ganglionated Plexi Ablation in Patients With Paroxysmal Atrial Fibrillation: A Randomized Study[NCT00671905] | 150 participants (Anticipated) | Interventional | 2008-05-31 | Completed | |||
| Potential Biomarkers in the Study of Overactive Bladder in Women[NCT03516292] | 108 participants (Anticipated) | Observational | 2018-01-29 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for carbachol and Disease Models, Animal
| Article | Year |
|---|---|
[Modeling parkinsonism (review)].
Topics: Aluminum; Animals; Carbachol; Cats; Caudate Nucleus; Chlorides; Chlorpromazine; Disease Models, Anim | 1982 |
Drug-induced dyskinesia in monkeys.
Topics: Amphetamine; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Azides; Carbachol; Caudate Nucle | 1975 |
Metabolic and neurophysiologic sequelae of brain injury: a cholinergic hypothesis.
Topics: Animals; Brain Concussion; Carbachol; Cats; Cholinergic Fibers; Disease Models, Animal; Electroencep | 1986 |
1 trial available for carbachol and Disease Models, Animal
| Article | Year |
|---|---|
Pharmacological effects of aqueous-ethanolic extract of Hibiscus rosasinensis on volume and acidity of stimulated gastric secretion.
Topics: Animals; Anti-Ulcer Agents; Calcium Channel Blockers; Carbachol; Cimetidine; Disease Models, Animal; | 2011 |
217 other studies available for carbachol and Disease Models, Animal
| Article | Year |
|---|---|
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Dr | 2020 |
Phenylephrine increases tear cathepsin S secretion in healthy murine lacrimal gland acinar cells through an alternative secretory pathway.
Topics: Acinar Cells; Adrenergic alpha-1 Receptor Agonists; Animals; beta-N-Acetylhexosaminidases; Blotting, | 2021 |
Combined agonists act synergistically to increase mucociliary clearance in a cystic fibrosis airway model.
Topics: Animals; Carbachol; Colforsin; Cystic Fibrosis; Disease Models, Animal; Drug Synergism; Drug Therapy | 2021 |
Inhibition of IP3R/Ca2+ Dysregulation Protects Mice From Ventilator-Induced Lung Injury
Topics: Animals; Apoptosis; Boron Compounds; Calcium; Calcium Chelating Agents; Calcium Signaling; Carbachol | 2021 |
Sinus node-like pacemaker mechanisms regulate ectopic pacemaker activity in the adult rat atrioventricular ring.
Topics: Action Potentials; Animals; Atrioventricular Node; Calcium Signaling; Carbachol; Cardiac Electrophys | 2019 |
Central muscarinic receptor subtypes (M1 and M3) involved in carbacol-induced hypophagia in neonatal broiler chicken.
Topics: Animals; Animals, Newborn; Behavior, Animal; Carbachol; Chickens; Disease Models, Animal; Eating; In | 2020 |
Disturbed Gastrointestinal Contractility in a Polycystic Ovary Syndrome Rat Model.
Topics: Acetylcholine; Animals; Calcium Signaling; Carbachol; Colon; Dihydrotestosterone; Disease Models, An | 2020 |
Chemical stimulation of the lateral hypothalamus induces antiallodynic and anti-thermal hyperalgesic effects in animal model of neuropathic pain: Involvement of orexin receptors in the spinal cord.
Topics: Animals; Benzoxazoles; Carbachol; Disease Models, Animal; Dose-Response Relationship, Drug; Hot Temp | 2020 |
Airway submucosal glands from cystic fibrosis swine suffer from abnormal ion transport across the serous acini, collecting duct, and ciliated duct.
Topics: Acinar Cells; Animals; Carbachol; Cations, Monovalent; Chlorides; Cilia; Colforsin; Cystic Fibrosis; | 2020 |
Hyperbaric oxygen therapy prevents subarachnoid hemorrhage-induced apoptosis and impaired contractility of the rabbit bladder.
Topics: Animals; Apoptosis; Carbachol; Caspase 3; Disease Models, Animal; Hyperbaric Oxygenation; Male; Musc | 2020 |
Noninvasive assessment of autonomic modulation of heart rate variability in the Ts65Dn mouse model of Down syndrome: A proof of principle study.
Topics: Adrenergic beta-Agonists; Animals; Autonomic Nervous System; Carbachol; Cholinergic Agonists; Diseas | 2020 |
Role of orexin receptors within the dentate gyrus in antinociception induced by chemical stimulation of the lateral hypothalamus in an animal model of inflammatory pain.
Topics: Acute Pain; Analgesics, Non-Narcotic; Animals; Carbachol; Dentate Gyrus; Disease Models, Animal; Hyp | 2020 |
Chronic cannabidiol treatment reduces the carbachol-induced coronary constriction and left ventricular cardiomyocyte width of the isolated hypertensive rat heart.
Topics: Adrenergic beta-Agonists; Animals; Antihypertensive Agents; Cannabidiol; Carbachol; Cell Size; Coron | 2021 |
Identification of two preclinical canine models of atrial fibrillation to facilitate drug discovery.
Topics: Animals; Atrial Fibrillation; Carbachol; Cardiotonic Agents; Disease Models, Animal; Dogs; Dose-Resp | 2021 |
Rab27a Contributes to Cathepsin S Secretion in Lacrimal Gland Acinar Cells.
Topics: Acinar Cells; Animals; Carbachol; Cathepsins; Cells, Cultured; Disease Models, Animal; Endosomes; La | 2021 |
Detrusor underactivity causes neurogenic voiding dysfunction in a rat bilateral accessory nerve-injury model.
Topics: Accessory Nerve Injuries; Animals; Carbachol; Disease Models, Animal; Gene Expression; Isometric Con | 2021 |
Impaired regulation of heart rate and sinoatrial node function by the parasympathetic nervous system in type 2 diabetic mice.
Topics: Animals; Carbachol; Cholinergic Agonists; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Disease | 2021 |
Micturition dysfunction in four-month old ovariectomized rats: Effects of testosterone replacement.
Topics: Acetanilides; Androgens; Angiotensin II; Animals; Carbachol; Disease Models, Animal; Dose-Response R | 2017 |
Agmatine attenuates intestinal ischemia and reperfusion injury by reducing oxidative stress and inflammatory reaction in rats.
Topics: Agmatine; Animals; Carbachol; Disease Models, Animal; Inflammation; Intestine, Small; Male; Malondia | 2017 |
Altered gastrointestinal motility in an animal model of Lesch-Nyhan disease.
Topics: Animals; Atropine; Benzazepines; Brain; Carbachol; Cytokines; Disease Models, Animal; Dopamine; Enzy | 2018 |
Role of D1- and D2-like dopaminergic receptors in the nucleus accumbens in modulation of formalin-induced orofacial pain: Involvement of lateral hypothalamus.
Topics: Analgesics; Analgesics, Non-Narcotic; Analysis of Variance; Animals; Carbachol; Disease Models, Anim | 2018 |
Deletion of IP
Topics: Animals; Carbachol; Cholinergic Agonists; Colon; Disease Models, Animal; Gastrointestinal Transit; I | 2019 |
Up-regulation of Rac1 in the bronchial smooth muscle of murine experimental asthma.
Topics: Animals; Asthma; Bronchi; Carbachol; Disease Models, Animal; Humans; Male; Mice; Muscle Contraction; | 2019 |
Long-term functional change of cryoinjury-induced detrusor underactivity and effects of extracorporeal shock wave therapy in a rat model.
Topics: Actins; Animals; Brain-Derived Neurotrophic Factor; Calcitonin Gene-Related Peptide; Carbachol; Chol | 2019 |
Long-term functional change of cryoinjury-induced detrusor underactivity and effects of extracorporeal shock wave therapy in a rat model.
Topics: Actins; Animals; Brain-Derived Neurotrophic Factor; Calcitonin Gene-Related Peptide; Carbachol; Chol | 2019 |
Long-term functional change of cryoinjury-induced detrusor underactivity and effects of extracorporeal shock wave therapy in a rat model.
Topics: Actins; Animals; Brain-Derived Neurotrophic Factor; Calcitonin Gene-Related Peptide; Carbachol; Chol | 2019 |
Long-term functional change of cryoinjury-induced detrusor underactivity and effects of extracorporeal shock wave therapy in a rat model.
Topics: Actins; Animals; Brain-Derived Neurotrophic Factor; Calcitonin Gene-Related Peptide; Carbachol; Chol | 2019 |
Immunization with 60 kD Ro peptide produces different stages of preclinical autoimmunity in a Sjögren's syndrome model among multiple strains of inbred mice.
Topics: Amino Acid Sequence; Animals; Antibodies, Antinuclear; Autoantigens; Autoimmunity; Carbachol; Diseas | 2013 |
Gap junction expression and the effects of gap junction inhibitors in overactive bladder models: does ovariectomy have a role?
Topics: Analysis of Variance; Animals; Blotting, Western; Carbachol; Connexin 43; Disease Models, Animal; Fe | 2013 |
K(Ca)3.1 channel-blockade attenuates airway pathophysiology in a sheep model of chronic asthma.
Topics: Acetamides; Airway Remodeling; Airway Resistance; Animals; Asthma; Blood Vessels; Bronchoalveolar La | 2013 |
Effects of chronic treatment with cilostazol, a phosphodiesterase 3 inhibitor, on female rat bladder in a partial bladder outlet obstruction model.
Topics: Animals; Carbachol; Cilostazol; Disease Models, Animal; Electric Stimulation; Female; Muscle Contrac | 2014 |
Regional differences of microglial accumulation within 72 hours of hypoxia-ischemia and the effect of acetylcholine receptor agonist on brain damage and microglial activation in newborn rats.
Topics: Animals; Animals, Newborn; Brain; Carbachol; Carotid Artery Diseases; Cerebral Cortex; Cholinergic A | 2014 |
Androgens are bronchoactive drugs that act by relaxing airway smooth muscle and preventing bronchospasm.
Topics: Androgens; Animals; Bronchial Spasm; Bronchoconstriction; Bronchoconstrictor Agents; Bronchodilator | 2014 |
The subpopulation of microglia expressing functional muscarinic acetylcholine receptors expands in stroke and Alzheimer's disease.
Topics: Alzheimer Disease; Animals; Brain; Carbachol; Disease Models, Animal; Female; Glioma; Macrophages; M | 2016 |
Altered parasympathetic nervous system regulation of the sinoatrial node in Akita diabetic mice.
Topics: Acetylcholine; Action Potentials; Animals; Carbachol; Cardiotonic Agents; Diabetes Mellitus, Experim | 2015 |
Contractile profile of esophageal and gastric fundus strips in experimental doxorubicin-induced esophageal atresia.
Topics: Animals; Antibiotics, Antineoplastic; Carbachol; Cholinergic Agonists; Disease Models, Animal; Doxor | 2015 |
GABAergic regulation of cerebellar NG2 cell development is altered in perinatal white matter injury.
Topics: Action Potentials; Animals; Animals, Newborn; Asphyxia Neonatorum; Carbachol; Cell Count; Cells, Cul | 2015 |
Characterization of Aldh2 (-/-) mice as an age-related model of cognitive impairment and Alzheimer's disease.
Topics: Aging; Aldehyde Dehydrogenase; Aldehyde Dehydrogenase, Mitochondrial; Aldehydes; Alzheimer Disease; | 2015 |
Defective parasympathetic innervation is associated with airway branching abnormalities in experimental CDH.
Topics: Animals; Calcium Channel Blockers; Carbachol; Cardiotonic Agents; Disease Models, Animal; Embryo, Ma | 2015 |
proBDNF and p75NTR Control Excitability and Persistent Firing of Cortical Pyramidal Neurons.
Topics: Action Potentials; Aminoquinolines; Animals; Brain-Derived Neurotrophic Factor; Carbachol; Cells, Cu | 2015 |
Urinary Bladder Dysfunction in Transgenic Sickle Cell Disease Mice.
Topics: Acetanilides; Adenosine Triphosphate; Anemia, Sickle Cell; Animals; Atropine; Calcium Chloride; Carb | 2015 |
Manifestation of automaticity in the pulmonary-vein myocardium of rats with abdominal aorto-venocaval shunt.
Topics: Action Potentials; Anastomosis, Surgical; Animals; Aorta, Abdominal; Bee Venoms; Calcium Chelating A | 2015 |
IP3R deficit underlies loss of salivary fluid secretion in Sjögren's Syndrome.
Topics: Acinar Cells; Animals; Calcium; Calcium Signaling; Carbachol; Case-Control Studies; Cell Size; Cells | 2015 |
Role of orexin-2 receptors in the nucleus accumbens in antinociception induced by carbachol stimulation of the lateral hypothalamus in formalin test.
Topics: Analgesics, Non-Narcotic; Animals; Carbachol; Disease Models, Animal; Dose-Response Relationship, Dr | 2016 |
Potential Role of Regulator of G-Protein Signaling 5 in the Protection of Vagal-Related Bradycardia and Atrial Tachyarrhythmia.
Topics: Acetylcholine; Action Potentials; Animals; Bradycardia; Carbachol; Cholinergic Agonists; Disease Mod | 2016 |
Imbalanced Rab3D versus Rab27 increases cathepsin S secretion from lacrimal acini in a mouse model of Sjögren's Syndrome.
Topics: Animals; Carbachol; Cathepsins; Cells, Cultured; Disease Models, Animal; Genotype; Lacrimal Apparatu | 2016 |
The effect of cannabinoids on dinitrofluorobenzene-induced experimental asthma in mice.
Topics: Acetylcholine; Animals; Anti-Asthmatic Agents; Asthma; Atropine; Cannabinoid Receptor Agonists; Cann | 2016 |
Activity of muscarinic, galanin and cannabinoid receptors in the prodromal and advanced stages in the triple transgenic mice model of Alzheimer's disease.
Topics: Aging; Alzheimer Disease; Animals; Autoradiography; Brain; Carbachol; Disease Models, Animal; Diseas | 2016 |
Functional interaction between orexin-1 and CB1 receptors in the periaqueductal gray matter during antinociception induced by chemical stimulation of the lateral hypothalamus in rats.
Topics: Animals; Benzoxazoles; Carbachol; Disease Models, Animal; Hypothalamic Area, Lateral; Male; Microinj | 2016 |
Vagotomy diminishes obesity in cafeteria rats by decreasing cholinergic potentiation of insulin release.
Topics: 1-Methyl-3-isobutylxanthine; Adipose Tissue; Animals; Body Weight; Carbachol; Colforsin; Cyclic AMP; | 2016 |
Toll-Like Receptor 4 Activation Contributes to Diabetic Bladder Dysfunction in a Murine Model of Type 1 Diabetes.
Topics: Animals; Carbachol; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetic Nephropathi | 2016 |
The effect of doxazosin and sildenafil citrate combination on bladder tissue contractility, alpha adrenergic receptor, and iNOS subtype expression in a male rat model of partially bladder outlet obstruction.
Topics: Adrenergic alpha-1 Receptor Antagonists; Animals; Carbachol; Disease Models, Animal; Doxazosin; Male | 2017 |
Role of orexin-2 and CB1 receptors within the periaqueductal gray matter in lateral hypothalamic-induced antinociception in rats.
Topics: Animals; Carbachol; Disease Models, Animal; Dose-Response Relationship, Drug; Hypothalamic Area, Lat | 2017 |
The histopathological and pharmacodynamic effects of intradetrusor decorin injected in a rabbit partial bladder outlet obstruction model.
Topics: Animals; Carbachol; Decorin; Disease Models, Animal; Electric Stimulation; Fibrosis; Injections, Int | 2017 |
Partial outlet obstruction of the rabbit urinary bladder induces selective protein oxidation.
Topics: Animals; Blotting, Western; Carbachol; Cholinergic Agonists; Cytoskeletal Proteins; Disease Models, | 2008 |
The loss and progressive recovery of voiding after spinal cord interruption in rats is associated with simultaneous changes in autonomous contractile bladder activity.
Topics: Animals; Carbachol; Disease Models, Animal; Female; In Vitro Techniques; Muscarinic Agonists; Muscle | 2009 |
Estrogen administration attenuates bladder outlet obstruction induced oxidative stress in the female rabbit.
Topics: Adenosine Triphosphate; Animals; Antioxidants; Carbachol; Choline O-Acetyltransferase; Cholinergic A | 2009 |
Inhibitory effect of state independent ponto-geniculo-occipital waves on seizure occurrence induced by local application of penicillin into the temporal lobe amygdala.
Topics: Amygdala; Analgesics, Non-Narcotic; Animals; Brain Mapping; Carbachol; Cats; Disease Models, Animal; | 2008 |
Effects of long-term dietary soy treatment on female urethral morphology and function in ovariectomized nonhuman primates.
Topics: Animals; Carbachol; Dietary Proteins; Disease Models, Animal; Female; Immunohistochemistry; Macaca f | 2008 |
Curcumin reverses attenuated carbachol-induced contraction of the colon in a rat model of colitis.
Topics: Animals; Carbachol; Colitis; Colon; Curcumin; Disease Models, Animal; Male; Muscle Contraction; NF-k | 2009 |
Prophylactic role of oral L-arginine on histological and contractile changes in a rat chronic bladder injury model.
Topics: Administration, Oral; Adrenergic beta-Agonists; Animals; Arginine; Carbachol; Cholinergic Agonists; | 2008 |
Ovalbumin-induced sensitization affects non-quantal acetylcholine release from motor nerve terminals and alters contractility of skeletal muscles in mice.
Topics: Acetylcholine; Animals; Carbachol; Cholinergic Agonists; Disease Models, Animal; Electrophysiology; | 2009 |
Lateral hypothalamic-induced alpha-adrenoceptor modulation occurs in a model of inflammatory pain in rats.
Topics: Adrenergic alpha-Antagonists; Animals; Carbachol; Cholinergic Agonists; Disease Models, Animal; Fema | 2009 |
G proteins in rat prefrontal cortex (PFC) are differentially activated as a function of oxygen status and PFC region.
Topics: Acetylcholine; Analgesics, Opioid; Animals; Carbachol; Cholinergic Agonists; Disease Models, Animal; | 2009 |
Activation of muscarinic receptors elicits inotropic responses in ventricular muscle from rats with heart failure through myosin light chain phosphorylation.
Topics: Animals; Blood Pressure; Calcium; Carbachol; Cardiac Myosins; Cardiotonic Agents; Disease Models, An | 2009 |
Alterations of urine TGF-beta1 and bFGF following bladder outlet obstruction: a predictor for detrusor contractibility?
Topics: Animals; Biomarkers; Carbachol; Cholinergic Agonists; Disease Models, Animal; Female; Fibroblast Gro | 2009 |
Role of SREBP-1 in the development of parasympathetic dysfunction in the hearts of type 1 diabetic Akita mice.
Topics: Animals; Carbachol; Cells, Cultured; Chick Embryo; Cholinergic Agents; Diabetes Mellitus, Type 1; Di | 2009 |
[The effect of carbachol on pulmonary vascular permeability and lung water content during oral fluid resuscitation of burn shock induced by a 50% total body surface area full-thickness flame injury in dogs].
Topics: Animals; Body Surface Area; Burns; Capillary Permeability; Carbachol; Disease Models, Animal; Dogs; | 2009 |
Activation of PPARgamma by rosiglitazone attenuates intestinal Cl- secretion.
Topics: Administration, Oral; Animals; Calcium; Carbachol; Chlorides; Cholera Toxin; Colforsin; Colon; Cycli | 2009 |
Food allergy alters jejunal circular muscle contractility and induces local inflammatory cytokine expression in a mouse model.
Topics: Animals; Carbachol; Cholinergic Agents; Cytokines; Disease Models, Animal; Female; Food Hypersensiti | 2009 |
Nonlinear dynamical analysis of carbachol induced hippocampal oscillations in mice.
Topics: Age Factors; Alzheimer Disease; Animals; Carbachol; Cholinergic Agonists; Disease Models, Animal; El | 2009 |
Deletion of TRPC3 in mice reduces store-operated Ca2+ influx and the severity of acute pancreatitis.
Topics: Actins; Acute Disease; Animals; Calcium Signaling; Carbachol; Ceruletide; Cholinergic Agonists; Dise | 2009 |
Cholinergic stimulation of the nucleus basalis of Meynert and reticular thalamic nucleus affects spike-and-wave discharges in WAG/Rij rats.
Topics: Animals; Basal Nucleus of Meynert; Carbachol; Cholinergic Agonists; Disease Models, Animal; Electroe | 2009 |
[The protective effects of carbachol on visceral ischemia-induced lipid peroxidation injury in rats with sepsis].
Topics: Animals; Carbachol; Disease Models, Animal; Hemodynamics; Ischemia; Lipid Peroxidation; Male; Random | 2009 |
Herpes simplex virus type 1 infection of the rat enteric nervous system evokes small-bowel neuromuscular abnormalities.
Topics: Acetylcholine; Animals; Calcium Chloride; Carbachol; CD3 Complex; Disease Models, Animal; Dose-Respo | 2010 |
Autonomic modulation and antiarrhythmic therapy in a model of long QT syndrome type 3.
Topics: Action Potentials; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Anti-Arrhythmia A | 2010 |
The effects of chronic hyperlipidemia on bladder function in myocardial infarction-prone Watanabe heritable hyperlipidemic (WHHLMI) rabbits.
Topics: Animals; Atherosclerosis; Calcitonin Gene-Related Peptide; Carbachol; Cholinergic Agonists; Chronic | 2010 |
FIZZ1 potentiates the carbachol-induced tracheal smooth muscle contraction.
Topics: Animals; Asthma; Bronchoalveolar Lavage Fluid; Carbachol; Cholinergic Agonists; Disease Models, Anim | 2010 |
Altered calcium signaling in an experimental model of glaucoma.
Topics: Adenosine Triphosphate; Animals; Axons; Calcium; Calcium Signaling; Carbachol; Cholinergic Agonists; | 2010 |
Role of constitutively active acetylcholine-mediated potassium current in atrial contractile dysfunction caused by atrial tachycardia remodelling.
Topics: Acetylcholine; Animals; Atrial Fibrillation; Bee Venoms; Calcium Channels; Carbachol; Disease Models | 2010 |
Carbachol alleviates rat cytokine release and organ dysfunction induced by lipopolysaccharide.
Topics: Animals; Carbachol; Cells, Cultured; Cholinergic Agonists; Cytokines; Disease Models, Animal; Enzyme | 2011 |
Control of enteric neuromuscular functions by purinergic A(3) receptors in normal rat distal colon and experimental bowel inflammation.
Topics: Adenosine; Adenosine Deaminase; Animals; Benzenesulfonates; Carbachol; Colitis; Colon; Disease Model | 2010 |
Acetylcholine receptor agonist reduces brain damage induced by hypoxia-ischemia in newborn rats.
Topics: Animals; Animals, Newborn; Asphyxia; CA1 Region, Hippocampal; CA2 Region, Hippocampal; CA3 Region, H | 2011 |
Decoding state transitions in hippocampal oscillatory activity in mice.
Topics: Alzheimer Disease; Animals; Carbachol; Disease Models, Animal; Hippocampus; Markov Chains; Mice; Mic | 2010 |
Aggravation of seizure-associated microvascular injuries by ibuprofen may involve multiple pathways.
Topics: Animals; Brain; Brain Edema; Carbachol; Cyclooxygenase Inhibitors; Disease Models, Animal; Ibuprofen | 2010 |
Effects of the gonadotropin-releasing hormone antagonist ganirelix on normal micturition and prostaglandin E(2)-induced detrusor overactivity in conscious female rats.
Topics: Administration, Intravesical; Animals; Blotting, Western; Carbachol; Cholinergic Agonists; Conscious | 2011 |
TRPA1 receptor modulation attenuates bladder overactivity induced by spinal cord injury.
Topics: Acetanilides; Acrolein; Animals; Ankyrins; Calcium Channels; Capsaicin; Carbachol; Disease Models, A | 2011 |
Ethanol enhances carbachol-induced protease activation and accelerates Ca2+ waves in isolated rat pancreatic acini.
Topics: Alcoholism; Animals; Calcium; Carbachol; Chymotrypsin; Dantrolene; Disease Models, Animal; Ethanol; | 2011 |
The effect of intravesical acetylsalicylic acid instillation on tissue prostaglandin levels after partial bladder outlet obstruction in rabbits.
Topics: Administration, Intravesical; Animals; Aspirin; Carbachol; Collagen; Dinoprost; Dinoprostone; Diseas | 2011 |
G-protein-associated signal transduction processes are restored after postweaning environmental enrichment in Ts65Dn, a Down syndrome mouse model.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Adrenergic alpha-Agonists; Adrenergic be | 2011 |
Colonic inflammation increases the contribution of muscarinic M2 receptors to carbachol-induced contraction of the rat colon.
Topics: Animals; Carbachol; Colitis; Colon; Diamines; Disease Models, Animal; Inflammation; Isometric Contra | 2011 |
Blebbistain, a myosin II inhibitor, as a novel strategy to regulate detrusor contractility in a rat model of partial bladder outlet obstruction.
Topics: Animals; Carbachol; Disease Models, Animal; Gene Expression Regulation; Heterocyclic Compounds, 4 or | 2011 |
Skeletal muscle IP3R1 receptors amplify physiological and pathological synaptic calcium signals.
Topics: Action Potentials; Animals; Boron Compounds; Calcium; Calcium Signaling; Calpain; Carbachol; Caspase | 2011 |
In-vitro characterization of the pharmacological effects induced by (-)-α-bisabolol in rat smooth muscle preparations.
Topics: Animals; Carbachol; Cystitis; Disease Models, Animal; Duodenum; Ifosfamide; In Vitro Techniques; Inf | 2012 |
A novel animal model of underactive bladder: analysis of lower urinary tract function in a rat lumbar canal stenosis model.
Topics: Animals; Carbachol; Cauda Equina; Cholinergic Agonists; Disease Models, Animal; Dose-Response Relati | 2012 |
Influence of experimental periodontitis on cholinergic stimulation of K⁺ release in rat parotid glands.
Topics: Animals; Carbachol; Cell Membrane; Cholinergic Agonists; Cyclooxygenase Inhibitors; Disease Models, | 2012 |
Effect of silymarin on bladder overactivity in cyclophosphamide-induced cystitis rat model.
Topics: Animals; Carbachol; Cyclophosphamide; Cystitis; Disease Models, Animal; Female; Muscle Contraction; | 2012 |
Structure and function of the pancreas in the polycystic kidney rat.
Topics: Amylases; Animals; Aquaporin 1; Bile; Carbachol; Cholinergic Agonists; Disease Models, Animal; Human | 2012 |
Unprovoked atrial tachyarrhythmias in aging spontaneously hypertensive rats: the role of the autonomic nervous system.
Topics: Age Factors; Aging; Animals; Autonomic Nervous System; Blood Pressure; Carbachol; Cholinergic Agonis | 2012 |
The effect of hypercholesterolemia on carbachol-induced contractions of the detrusor smooth muscle in rats: increased role of L-type Ca2+ channels.
Topics: Amides; Animals; Calcium Channels, L-Type; Carbachol; Cholinergic Agonists; Disease Models, Animal; | 2012 |
Developmental programming of eNOS uncoupling and enhanced vascular oxidative stress in adult rats after transient neonatal oxygen exposure.
Topics: Age Factors; Animals; Animals, Newborn; Aorta; Arginine; Carbachol; Disease Models, Animal; Dose-Res | 2013 |
Role of PKC and CaV1.2 in detrusor overactivity in a model of obesity associated with insulin resistance in mice.
Topics: Adiposity; Amlodipine; Animals; Body Weight; Calcium Channel Blockers; Calcium Channels, L-Type; Cal | 2012 |
The spinal antinociceptive effects of cholinergic drugs in rats: receptor subtype specificity in different nociceptive tests.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Animals; Carbachol; Cholinergi | 2002 |
Disruption of PLC-beta 1-mediated signal transduction in mutant mice causes age-dependent hippocampal mossy fiber sprouting and neurodegeneration.
Topics: Aging; Alternative Splicing; Animals; Carbachol; Chromosome Mapping; Disease Models, Animal; Epileps | 2002 |
Effect of partial outlet obstruction on rabbit urinary bladder smooth muscle function.
Topics: Animals; Carbachol; Cholinergic Agonists; Disease Models, Animal; In Vitro Techniques; Isometric Con | 2003 |
Influence of postweaning social isolation in the rat on brain development, conditioned behavior, and neurotransmission.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Action Potentials; Adrenergic Agents; Amphetamine; Analysis | 2003 |
Increased connexin43-mediated intercellular communication in a rat model of bladder overactivity in vivo.
Topics: Animals; Carbachol; Cell Communication; Connexin 43; Disease Models, Animal; Female; Gap Junctions; | 2003 |
Effect of pharmacologically induced smooth muscle activation on permeability in murine colitis.
Topics: Albuterol; Animals; Biguanides; Carbachol; Colitis; Dextran Sulfate; Disease Models, Animal; Female; | 2003 |
Impaired modulation of GABAergic transmission by muscarinic receptors in a mouse transgenic model of Alzheimer's disease.
Topics: Action Potentials; Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Carbachol; Disease Mo | 2003 |
Involvement of cholinergic and gabaergic systems in the fragile X knockout mice.
Topics: Animals; Atropine; Carbachol; Cholinergic Agonists; Disease Models, Animal; Drug Interactions; Elect | 2003 |
Ca2+-independent muscarinic excitation of rat medial entorhinal cortex layer V neurons.
Topics: Acetylcholine; Action Potentials; Afferent Pathways; Animals; Calcium; Calcium Channel Blockers; Cal | 2003 |
Impaired gastric motility in the gastroesophageal reflux rat model: an in vitro study.
Topics: Animals; Carbachol; Cholinergic Agonists; Disease Models, Animal; Gastric Emptying; Gastric Fundus; | 2003 |
Altered autonomic control in rat intestine due to both infection with Anisakis simplex and incubation with the parasite's crude extract.
Topics: Adrenergic alpha-Agonists; Anaphylaxis; Angioedema; Animals; Anisakiasis; Anisakis; Antibodies, Helm | 2003 |
Cholinergic-adrenergic antagonism in the induction of tachyarrhythmia by electrical stimulation in isolated rat atria.
Topics: 1-Methyl-3-isobutylxanthine; Amiodarone; Animals; Anti-Arrhythmia Agents; Carbachol; Cholinergic Ago | 2004 |
Murine model for non-IgE-mediated asthma.
Topics: Animals; Asthma; Carbachol; Dermatitis, Contact; Dinitrofluorobenzene; Disease Models, Animal; Dose- | 2004 |
Effect of periurethral denervation on smooth muscles of the lower urinary tract.
Topics: Animals; Biopsy, Needle; Carbachol; Disease Models, Animal; Female; Immunohistochemistry; Muscle Con | 2004 |
[Enteral administration of carbachol on systemic inflammatory response and multiple organ dysfunction induced by partial ischemia/reperfusion injury to the gut].
Topics: Animals; Carbachol; Disease Models, Animal; Intestines; Kidney; Liver; Male; Multiple Organ Failure; | 2005 |
AMPA receptor desensitization as a determinant of vulnerability to focally evoked status epilepticus.
Topics: Animals; Behavior, Animal; Benzothiadiazines; Bicuculline; Carbachol; Cerebral Cortex; Cholinergic A | 2005 |
[Effects of carbachol on apoptosis of peripheral white blood cells and expression of cytokines in rats suffering from gut ischemia/reperfusion injury].
Topics: Animals; Apoptosis; Carbachol; Cytokines; Disease Models, Animal; Intestines; Leukocytes; Lymphocyte | 2005 |
Therapeutic targeting of endothelial ligands for L-selectin (PNAd) in a sheep model of asthma.
Topics: Animals; Antigens, Surface; Asthma; Bronchoalveolar Lavage; Carbachol; Carbohydrate Sulfotransferase | 2005 |
Indomethacin-induced ileitis is associated with tensiometric, vascular and oxidative changes in the experimental rat model.
Topics: Acetylcholine; Adrenergic alpha-Agonists; Animals; Carbachol; Cholinergic Agonists; Disease Models, | 2005 |
Mechanisms underlying the maintenance of muscle hypercontractility in a model of postinfective gut dysfunction.
Topics: Acute Disease; Animals; Carbachol; Cells, Cultured; Cholinergic Agonists; Chronic Disease; Cyclooxyg | 2005 |
Regional differences in gastrointestinal motility disturbances during acute necrotising pancreatitis.
Topics: Acute Disease; Animals; Carbachol; Choline Deficiency; Dietary Supplements; Dinoprost; Disease Model | 2005 |
Exacerbation of acute pancreatitis by combined cholinergic stimulation and duct obstruction.
Topics: alpha-Amylases; Animals; Bile Ducts, Extrahepatic; Carbachol; Cholestasis, Extrahepatic; Cholinergic | 2005 |
Loss of metabotropic glutamate receptor-mediated regulation of glutamate transport in chemically activated astrocytes in a rat model of amyotrophic lateral sclerosis.
Topics: Amyotrophic Lateral Sclerosis; Animals; Animals, Genetically Modified; Aspartic Acid; Astrocytes; Bl | 2006 |
Effect of hypothyroidism on the nitrergic relaxant responses of corpus cavernosal smooth muscle in rabbits.
Topics: Animals; Carbachol; Cholinergic Agonists; Disease Models, Animal; Electric Stimulation; Hypothyroidi | 2006 |
Muscarinic acetylcholine type-3 receptor desensitization due to chronic exposure to Sjögren's syndrome-associated autoantibodies.
Topics: Animals; Antibodies, Blocking; Autoantibodies; Carbachol; Disease Models, Animal; Dose-Response Rela | 2006 |
Involvement of the anion exchanger SLC26A6 in prostaglandin E2- but not forskolin-stimulated duodenal HCO3- secretion.
Topics: Animals; Antiporters; Bicarbonates; Carbachol; Colforsin; Cystic Fibrosis; Cystic Fibrosis Transmemb | 2006 |
Long-lasting changes in small intestinal transport following the recovery from Trichinella spiralis infection.
Topics: Animals; Biological Transport; Carbachol; Cholinergic Agonists; Disease Models, Animal; Electric Sti | 2006 |
Increased cholinergic contractions of jejunal smooth muscle caused by a high cholesterol diet are prevented by the 5-HT4 agonist--tegaserod.
Topics: Action Potentials; Animals; Carbachol; Cholesterol, Dietary; Cholinergic Agonists; Disease Models, A | 2006 |
Freezing infective-stage larvae from Anisakis simplex and their produce at -20 degrees C for 24 h does not prevent the occurrence of autonomic imbalance in rat ileum.
Topics: Animals; Anisakiasis; Anisakis; Autonomic Nervous System; Carbachol; Disease Models, Animal; Freezin | 2006 |
Continuous carbachol infusion promotes peripheral cell proliferation and mimics vagus hyperactivity in a rat model of hypothalamic obesity.
Topics: Animals; Body Weight; Carbachol; Cell Proliferation; Cholinergic Agonists; Disease Models, Animal; D | 2006 |
Mechanism underlying the reversal of contractility dysfunction in experimental colitis by cyclooxygenase-2 inhibition.
Topics: Animals; Blotting, Western; Carbachol; Colitis; Colon; Cyclooxygenase 2 Inhibitors; Disease Models, | 2006 |
Regulation of bladder muscarinic receptor subtypes by experimental pathologies.
Topics: Age Factors; Animals; Benzofurans; Carbachol; Denervation; Disease Models, Animal; Electric Stimulat | 2006 |
In vitro tracheal hyperresponsiveness to muscarinic receptor stimulation by carbachol in a rat model of bleomycin-induced pulmonary fibrosis.
Topics: Animals; Bleomycin; Bronchial Hyperreactivity; Calcium Signaling; Carbachol; Disease Models, Animal; | 2006 |
Intense sound-induced plasticity in the dorsal cochlear nucleus of rats: evidence for cholinergic receptor upregulation.
Topics: Acoustic Stimulation; Animals; Atropine; Carbachol; Cochlear Nucleus; Disease Models, Animal; Electr | 2007 |
Effect of hypothyroidism on the NO/cGMP pathway of corpus cavernosum in rabbits.
Topics: Animals; Carbachol; Cyclic GMP; Disease Models, Animal; Electric Stimulation; Hypothyroidism; Impote | 2006 |
[Influence of carbachol on intestinal dysfunction after traumatic or burn injury].
Topics: Adolescent; Adult; Animals; Burns; Carbachol; Disease Models, Animal; Female; Humans; Intestinal Muc | 2006 |
Efficacy of IL-13 neutralization in a sheep model of experimental asthma.
Topics: Amino Acid Sequence; Animals; Antibodies; Ascaris suum; Asthma; Base Sequence; Bronchial Hyperreacti | 2007 |
Effects of carbachol on lead-induced impairment of the long-term potentiation/depotentiation in rat dentate gyrus in vivo.
Topics: Administration, Oral; Animals; Carbachol; Cholinergic Agonists; Dentate Gyrus; Disease Models, Anima | 2007 |
[Effect of carbachol on dendritic cell function in the lipopolysaccharides induced murine sepsis model].
Topics: Animals; B7-2 Antigen; Carbachol; CD11c Antigen; Dendritic Cells; Disease Models, Animal; Genes, MHC | 2006 |
Intestinal inflammation downregulates smooth muscle CPI-17 through induction of TNF-alpha and causes motility disorders.
Topics: Animals; Carbachol; Disease Models, Animal; Down-Regulation; Escin; Gastrointestinal Motility; Ileit | 2007 |
Using caveolin-1 knockout mouse to study impaired detrusor contractility and disrupted muscarinic activity in the aging bladder.
Topics: Aging; Animals; Carbachol; Caveolin 1; Disease Models, Animal; Electric Stimulation; Male; Mice; Mic | 2007 |
Muscarinic modulation of the sodium-calcium exchanger in heart failure.
Topics: Adrenergic beta-Agonists; Animals; Carbachol; Cardiac Pacing, Artificial; Cell Separation; Cells, Cu | 2007 |
In vitro and in vivo effects of the atrial selective antiarrhythmic compound AVE1231.
Topics: Action Potentials; Analysis of Variance; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atri | 2007 |
Involvement of CPI-17 downregulation in the dysmotility of the colon from dextran sodium sulphate-induced experimental colitis in a mouse model.
Topics: Animals; Anticoagulants; Blotting, Western; Carbachol; Cholinergic Agonists; Colitis; Dextran Sulfat | 2007 |
[Effects of carbachol on apoptosis of intestinal epithelial cells after gut ischemia/reperfusion in rat].
Topics: Animals; Apoptosis; Carbachol; Caspase 3; Disease Models, Animal; Epithelial Cells; Intestinal Mucos | 2007 |
Intracellular calcium mobilization of the aganglionic intestine in the endothelin B receptor gene-deficient rat.
Topics: Animals; Calcium Channels, L-Type; Calcium Signaling; Carbachol; Cholinergic Agonists; Colon; Diseas | 2007 |
Gliadin-dependent neuromuscular and epithelial secretory responses in gluten-sensitive HLA-DQ8 transgenic mice.
Topics: Acetylcholine; Animals; Antibodies; Carbachol; Celiac Disease; Cholinergic Agonists; Disease Models, | 2008 |
Role of Ca2+-sensitization in attenuated carbachol-induced contraction of the colon in a rat model of colitis.
Topics: Animals; Blotting, Western; Calcium; Carbachol; Colitis; Colon; Disease Models, Animal; Gene Express | 2008 |
In vitro sensitivity of mouse esophagus to agonists in different pH medium values.
Topics: Acetylcholine; Adrenergic beta-Agonists; Analysis of Variance; Animals; Carbachol; Cholinergic Agoni | 2007 |
Pulmonary vein region ablation in experimental vagal atrial fibrillation: role of pulmonary veins versus autonomic ganglia.
Topics: Animals; Atrial Fibrillation; Carbachol; Catheter Ablation; Cholinergic Agonists; Disease Models, An | 2008 |
Gastric motor effects of ghrelin and growth hormone releasing peptide 6 in diabetic mice with gastroparesis.
Topics: Alloxan; Animals; Carbachol; Cholinergic Agents; Diabetes Mellitus, Experimental; Disease Models, An | 2008 |
[Effect of carbachol on intestinal mucosa blood flow and absorption rate of glucose-electrolyte solution during enteral resuscitation for 50% total body surface area full-thickness burn injury in dog].
Topics: Animals; Burns; Carbachol; Disease Models, Animal; Dogs; Electrolytes; Fluid Therapy; Glucose; Intes | 2008 |
[Effect of carbachol on gastric emptying and gastric mucosa partial pressure of carbon dioxide in oral resuscitation of burn shock with a glucose-electrolyte solution in dogs].
Topics: Administration, Oral; Animals; Burns; Carbachol; Carbon Dioxide; Disease Models, Animal; Dogs; Elect | 2008 |
Very mild disease phenotype of congenic CftrTgH(neoim)Hgu cystic fibrosis mice.
Topics: Analysis of Variance; Animals; Body Weight; Carbachol; Chlorides; Colforsin; Cystic Fibrosis; Cystic | 2008 |
The effect of ischemia/reperfusion on rabbit bladder--role of Rho-kinase and smooth muscle regulatory proteins.
Topics: Animals; Blotting, Western; Calmodulin-Binding Proteins; Carbachol; Contractile Proteins; Disease Mo | 2009 |
Further electrophysiological studies of neuromuscular transmission in an animal model of myasthenia gravis.
Topics: Action Potentials; Animals; Carbachol; Disease Models, Animal; Evoked Potentials; Female; Myasthenia | 1981 |
The importance of the amygdala in the effect of antidepressants on olfactory bulbectomised rats.
Topics: Amygdala; Animals; Antidepressive Agents; Avoidance Learning; Carbachol; Depression; Disease Models, | 1982 |
Heightened cholinergic responsiveness in IgE-producing rabbits.
Topics: Animals; Carbachol; Disease Models, Animal; Histamine; Hypersensitivity, Immediate; Immunoglobulin E | 1984 |
Effect of carbachol and atropine perfusions in the mesencephalic tegmentum and caudate nucleus on experimental tremor in monkeys.
Topics: Animals; Atropine; Carbachol; Caudate Nucleus; Disease Models, Animal; Macaca mulatta; Parkinson Dis | 1982 |
Restraint ulcer: history, current research and future implications.
Topics: Aluminum Hydroxide; Animals; Carbachol; Cold Temperature; Disease Models, Animal; Emotions; Humans; | 1980 |
Mechanism of stimulation of gastrointestinal propulsion in postoperative ileus rats by 16,16-dimethyl PGE2.
Topics: 16,16-Dimethylprostaglandin E2; Animals; Atropine; Carbachol; Disease Models, Animal; Drug Interacti | 1980 |
Alterations of pancreatic amylase secretion in the reserpinized rat model of cystic fibrosis. Effects of cerulein and EGF.
Topics: Amylases; Animals; Carbachol; Ceruletide; Cystic Fibrosis; Disease Models, Animal; Epidermal Growth | 1994 |
An animal model of congenital defect of gene expression of cholecystokinin (CCK)-A receptor.
Topics: Amylases; Animals; Base Sequence; Blotting, Southern; Bombesin; Brain; Calcium; Carbachol; Disease M | 1995 |
Vascular reactivity in alcoholic rat aortas: in vitro interactions between catecholamines and alcohol.
Topics: Alcoholism; Animals; Aorta; Carbachol; Diabetes Mellitus, Experimental; Disease Models, Animal; Dose | 1995 |
Role of indomethacin-induced peptic ulceration in gastric acid secretion in pregnant rats.
Topics: Animals; Carbachol; Disease Models, Animal; Female; Gastric Acid; Histamine; Indomethacin; Peptic Ul | 1993 |
Pathogenesis of hyperacute experimental autoimmune myasthenia gravis. Acetylcholine receptor/cholinergic site/receptor function/autoimmunity.
Topics: Animals; Antibodies, Monoclonal; Autoimmunity; Bungarotoxins; Carbachol; Cholinergic Antagonists; Di | 1994 |
Effect of partial urethral obstruction on force development of the guinea pig bladder.
Topics: Animals; Carbachol; Disease Models, Animal; Electric Stimulation; Guinea Pigs; In Vitro Techniques; | 1993 |
Cardiac beta-adrenoceptors, G-proteins and adenylate cyclase regulation during myocardial hypertrophy.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Carbachol; Cardiomegaly; Cholera Toxin; Colfors | 1993 |
Insulin secretion, myo-inositol transport, and Na(+)-K(+)-ATPase in glucose-desensitized rat islets.
Topics: Animals; Arginine; Biological Transport; Carbachol; Cells, Cultured; Disease Models, Animal; Dose-Re | 1993 |
Effects of mild bladder outlet obstruction on rabbit bladder structure and function.
Topics: Analysis of Variance; Animals; Carbachol; Disease Models, Animal; Male; Muscle, Smooth; Rabbits; Uri | 1995 |
Inhibition of bronchospasm and ozone-induced airway hyperresponsiveness in the guinea-pig by CDP840, a novel phosphodiesterase type 4 inhibitor.
Topics: Analysis of Variance; Animals; Benzamides; Bronchial Hyperreactivity; Bronchoconstriction; Carbachol | 1996 |
Loss of endothelium-mediated vascular relaxation as a response to various clamping pressures.
Topics: Adrenergic alpha-Agonists; Animals; Carbachol; Constriction; Dilatation, Pathologic; Disease Models, | 1996 |
LFA-1 and ICAM-1 are crucial for the induction of hyperreactivity in the mouse airways.
Topics: Animals; Antibodies, Monoclonal; Asthma; Bronchial Hyperreactivity; Carbachol; Disease Models, Anima | 1996 |
Plasma protein extravasation induced in the rat dura mater by stimulation of the parasympathetic sphenopalatine ganglion.
Topics: Acetylcholine; Afferent Pathways; Animals; Atropine; Axons; Blood Pressure; Blood Proteins; Calciton | 1997 |
Guinea pig pulmonary mechanics: altered sensitivity to carbachol by cadmium and/or selenium.
Topics: Animals; Bronchoconstriction; Cadmium Chloride; Carbachol; Carcinogens; Disease Models, Animal; Dose | 1998 |
Use of abdominal fascia to create partial outlet obstruction in rabbits.
Topics: Adenosine Triphosphate; Animals; Carbachol; Disease Models, Animal; Electric Stimulation; Male; Musc | 1998 |
Effect of repetitive stimulation on the contractile response of rabbit urinary bladder subjected to in vitro hypoxia or in vitro ischemia followed by reoxygenation.
Topics: Animals; Carbachol; Cell Hypoxia; Disease Models, Animal; Electric Stimulation; Glucose; In Vitro Te | 1998 |
Megacystis, mydriasis, and ion channel defect in mice lacking the alpha3 neuronal nicotinic acetylcholine receptor.
Topics: Animals; Carbachol; Disease Models, Animal; Electric Stimulation; Electrophysiology; Gene Targeting; | 1999 |
Endogenous interleukin-10 suppresses allergen-induced airway inflammation and nonspecific airway responsiveness.
Topics: Allergens; Animals; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoalveolar | 2000 |
Differences in time-related cardiopulmonary responses to hypoxia in three rat strains.
Topics: Altitude; Animals; Carbachol; Disease Models, Animal; Endothelin-1; Endothelins; Hypertension, Pulmo | 2000 |
Obstructive response of human bladder to BPH vs. rabbit bladder response to partial outlet obstruction: a direct comparison.
Topics: Adaptation, Physiological; Animals; Bethanechol; Calcium Signaling; Calcium-Transporting ATPases; Ca | 2000 |
Antigen-induced bronchial hyperreactivity and bronchopulmonary inflammation in rats: effect of TNF receptor binding protein.
Topics: Animals; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Bronchopneumonia; Carbachol; Carri | 2001 |
Effect of purified lipopolysaccharides from strains of Helicobacter pylori and Helicobacter felis on acid secretion in mouse gastric glands in vitro.
Topics: Animals; Carbachol; Dinoprostone; Disease Models, Animal; Duodenal Ulcer; Female; Gastric Acid; Gast | 2001 |
Induction of atrial tachycardia and fibrillation in the mouse heart.
Topics: Animals; Atrial Fibrillation; Autonomic Nervous System; Carbachol; Cardiac Pacing, Artificial; Cardi | 2001 |
Evaluation of the role of I(KACh) in atrial fibrillation using a mouse knockout model.
Topics: Animals; Atrial Fibrillation; Carbachol; Cholinergic Agonists; Disease Models, Animal; Electrocardio | 2001 |
Effect of endogenous catecholamine on myocardial stunning in a simulated ischemia model.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Adrenergic Uptake Inhibitors; Animals; Carbac | 2001 |
Lacrimal gland fluid secretion and lymphocytic infiltration in the NZB/W mouse model of Sjögren's syndrome.
Topics: Administration, Topical; Animals; Carbachol; Disease Models, Animal; Female; Lacrimal Apparatus; Lym | 2001 |
Increased smooth muscle contractility of intestine in the genetic null of the endothelin ETB receptor: a rat model for long segment Hirschsprung's disease.
Topics: Animals; Carbachol; Cholinergic Agonists; Disease Models, Animal; Dose-Response Relationship, Drug; | 2002 |
Dextran sodium sulphate-induced colitis perturbs muscarinic cholinergic control of colonic epithelial ion transport.
Topics: Animals; Atropine; Carbachol; Cholinergic Agonists; Colitis; Dextran Sulfate; Disease Models, Animal | 2002 |
Effect of quercitrin on the early stages of hapten induced colonic inflammation in the rat.
Topics: Alkaline Phosphatase; Animals; Antidiarrheals; Biological Transport; Carbachol; Colitis, Ulcerative; | 2002 |
Accumulated endogenous NOS inhibitors, decreased NOS activity, and impaired cavernosal relaxation with ischemia.
Topics: Animals; Arginine; Calcium; Carbachol; Cholinergic Agonists; Cyclic GMP; Disease Models, Animal; Dos | 2002 |
Fluticasone inhibits the progression of allergen-induced structural airway changes.
Topics: Administration, Inhalation; Administration, Topical; Allergens; Androstadienes; Animals; Anti-Inflam | 2002 |
A pharmacologic model of Huntington's chorea.
Topics: Animals; Carbachol; Catheterization; Clozapine; Corpus Striatum; Disease Models, Animal; Dyskinesia, | 1976 |
Effects of cimetidine, a histamine H2-receptor antagonist, on various experimental gastric and duodenal ulcers.
Topics: Administration, Oral; Animals; Aspirin; Carbachol; Depression, Chemical; Disease Models, Animal; Duo | 1977 |
An in vitro model of canine immediate-type hypersensitivity reactions.
Topics: Animals; Antigens; Ascaris; Carbachol; Cromolyn Sodium; Disease Models, Animal; Dogs; Guanidines; Hi | 1976 |
Morphologic and immunologic studies in experimental autoimmune myasthenia gravis and myasthenia gravis.
Topics: Acetylcholine; Animals; Antibody Formation; Autoimmune Diseases; Binding Sites, Antibody; Bungarotox | 1977 |
Proceedings: Secretagogue-produced duodenal ulcers in the rat and their prevention by the gastric secretory inhibitor UK 9040.
Topics: Animals; Carbachol; Disease Models, Animal; Duodenal Ulcer; Gastric Mucosa; Histamine H1 Antagonists | 1975 |
Effects of diethylcholine in two animal models of Parkinsonism tremors.
Topics: Animals; Brain Chemistry; Carbachol; Choline; Disease Models, Animal; Male; Mice; Parkinson Disease, | 1979 |
Carbachol stimulation of gastrointestinal transit in the postoperative lleus rat.
Topics: Anesthetics; Animals; Carbachol; Colonic Diseases; Disease Models, Animal; Gastric Emptying; Gastroi | 1979 |
The effect of cholinergic and anticholinergic agents on the primate model of allergic asthma.
Topics: Airway Resistance; Animals; Antigens; Asthma; Atropine; Carbachol; Disease Models, Animal; Female; H | 1976 |
A comparison of immunologic asthma to two types of cholinergic respiratory responses in the rhesus monkey.
Topics: Acetylcholine; Aerosols; Airway Resistance; Animals; Antigens; Ascaris; Asthma; Atropine; Carbachol; | 1976 |
Airway hyperreactivity to pharmacologic agents in rhesus monkeys cutaneously hypersensitive to Ascaris antigen.
Topics: Airway Resistance; Animals; Antigens; Ascaris; Carbachol; Disease Models, Animal; Dose-Response Rela | 1976 |
Circus movement in rabbit atrial muscle as a mechanism of tachycardia. III. The "leading circle" concept: a new model of circus movement in cardiac tissue without the involvement of an anatomical obstacle.
Topics: Action Potentials; Animals; Carbachol; Disease Models, Animal; Dose-Response Relationship, Drug; Ele | 1977 |
Natural history and morphology of secretagogue-induced duodenal ulcers in rats.
Topics: Animals; Carbachol; Disease Models, Animal; Duodenal Ulcer; Intestinal Mucosa; Male; Pentagastrin; R | 1975 |
Studies of the hyperkinetic syndrome -- Part I. An experimental analysis.
Topics: Amphetamine; Animals; Carbachol; Disease Models, Animal; Female; Humans; Hyperkinesis; Locomotion; P | 1975 |
Altered tracheal smooth muscle activities in an animal model of human myotonic dystrophy.
Topics: Animals; Carbachol; Cholesterol; Diazonium Compounds; Dibenzylchlorethamine; Disease Models, Animal; | 1976 |
Impairment of contractile response to carbachol and muscarinic receptor coupling in gastric antral smooth muscle cells isolated from diabetic streptozotocin-treated rats and db/db mice.
Topics: Animals; Carbachol; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Disease Models, Anim | 1992 |
[Acute and chronic disorders in gastric emptying after the x-ray irradiation of the rat stomach and their therapeutic modification].
Topics: Animals; Atropine; Carbachol; Disease Models, Animal; Drug Evaluation, Preclinical; Drug Therapy, Co | 1992 |
T-lymphocyte modulation of intestinal muscle function in the Trichinella-infected rat.
Topics: Analysis of Variance; Animals; Carbachol; Cell Division; Concanavalin A; Disease Models, Animal; Int | 1991 |
Alterations of amylase secretion in the chronically reserpinized rat: an acetylcholine-mediated phenomenon.
Topics: Acetylcholine; Amylases; Animals; Body Weight; Carbachol; Ceruletide; Cystic Fibrosis; Disease Model | 1991 |
Diarrhoea of famine and malnutrition: investigations using a rat model. 1. Jejunal hypersecretion induced by starvation.
Topics: Animals; Bethanechol; Bethanechol Compounds; Carbachol; Chlorides; Diarrhea; Disease Models, Animal; | 1990 |
Coma induced by cholinergic activation of a restricted region in the pontine reticular formation--a model of reversible forms of coma.
Topics: Animals; Brain Diseases; Carbachol; Cats; Coma; Disease Models, Animal; Pons; Reticular Formation | 1986 |
Prevention by prostaglandins of caerulein-induced pancreatitis in rats.
Topics: 16,16-Dimethylprostaglandin E2; Amylases; Animals; Carbachol; Ceruletide; Cholecystokinin; Dinoprost | 1989 |
The physiological response of the detrusor muscle to experimental bladder outflow obstruction in the pig.
Topics: Acetylcholine; Animals; Carbachol; Disease Models, Animal; Dose-Response Relationship, Drug; Muscle | 1987 |
The chronically pilocarpine-treated rat in the study of cystic fibrosis: investigations on submandibular gland and pancreas.
Topics: Animals; Carbachol; Cystic Fibrosis; Disease Models, Animal; Electron Probe Microanalysis; Energy Me | 1985 |
Trophic functions of the neuron. V. Familial dysautonomia. Choline acetyltransferase in familial dysautonomia.
Topics: Acetylcholine; Acetyltransferases; Animals; Autonomic Nervous System; Carbachol; Cats; Ciliary Body; | 1974 |
Chemical stimulation of discrete brain loci as a method of producing dyskinesia models in primates.
Topics: Animals; Basal Ganglia; Carbachol; Caudate Nucleus; Chorea; Disease Models, Animal; Extrapyramidal T | 1972 |
Analysis of local cholinergic tremor mechanisms following selective neurochemical lesions.
Topics: Acetylcholine; Animals; Basal Ganglia; Brain; Carbachol; Cats; Cholinesterase Inhibitors; Disease Mo | 1970 |