carbachol has been researched along with Diarrhea in 29 studies
Carbachol: A slowly hydrolyzed CHOLINERGIC AGONIST that acts at both MUSCARINIC RECEPTORS and NICOTINIC RECEPTORS.
Diarrhea: An increased liquidity or decreased consistency of FECES, such as running stool. Fecal consistency is related to the ratio of water-holding capacity of insoluble solids to total water, rather than the amount of water present. Diarrhea is not hyperdefecation or increased fecal weight.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Cr) protected against diarrhea caused by castor oil in rats and mice, similar to loperamide and dicyclomine, and bronchospasm caused by carbachol (CCh) in rats, similar to aminophylline." | 3.78 | Mechanisms underlying the antidiarrheal, antispasmodic and bronchodilator activities of Fumaria parviflora and involvement of tissue and species specificity. ( Al-Rehaily, AJ; Bashir, S; Gilani, AH, 2012) |
| " administration, for eight days, of the cholinesterase inhibitor disulfoton to rats produced mild to moderate signs of intoxication (tremors, incontinence and diarrhoea) but no deaths." | 3.65 | Response of the rat ileum, uterus and vas deferens to carbachol and acetylcholine following repeated daily administration of a cholinesterase inhibitor. ( Foley, DJ; McPhillips, JJ, 1973) |
| "Diarrhea is induced when NSP4, acting as a viral enterotoxin, triggers a signal transduction pathway." | 1.29 | Age-dependent diarrhea induced by a rotaviral nonstructural glycoprotein. ( Ball, JM; Estes, MK; Morris, AP; Tian, P; Zeng, CQ, 1996) |
| "Thus, diarrhea is not observed consistently and reliably in this species to allow valid evaluation of potential antidiarrheal agents." | 1.28 | Cecectomized rat. A model of experimental secretory diarrhea in conscious animals. ( Burnham, DB; Fondacaro, JD; Kolpak, DC; McCafferty, GP, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (20.69) | 18.7374 |
| 1990's | 5 (17.24) | 18.2507 |
| 2000's | 8 (27.59) | 29.6817 |
| 2010's | 7 (24.14) | 24.3611 |
| 2020's | 3 (10.34) | 2.80 |
| Authors | Studies |
|---|---|
| Hussain Shah, SA | 1 |
| Aleem, A | 1 |
| Rehman, NU | 2 |
| Ansari, MN | 1 |
| Samad, A | 1 |
| Kim, Y | 1 |
| Quach, A | 1 |
| Das, S | 1 |
| Barrett, KE | 4 |
| Shareef, H | 1 |
| Rizwani, GH | 1 |
| Mandukhail, SR | 1 |
| Watanabe, N | 1 |
| Gilani, AH | 5 |
| Bajwa, PJ | 1 |
| Lee, JW | 1 |
| Straus, DS | 1 |
| Lytle, C | 1 |
| Nakashima, Y | 1 |
| Ida, T | 1 |
| Sato, T | 1 |
| Nakamura, Y | 1 |
| Takahashi, T | 1 |
| Mori, K | 1 |
| Miyazato, M | 1 |
| Kangawa, K | 1 |
| Kusukawa, J | 1 |
| Kojima, M | 1 |
| Paul, G | 1 |
| Marchelletta, RR | 1 |
| McCole, DF | 1 |
| Bzik, VA | 1 |
| Medani, M | 1 |
| Baird, AW | 1 |
| Winter, DC | 1 |
| Brayden, DJ | 1 |
| Khan, M | 1 |
| Khan, AU | 2 |
| Bashir, S | 1 |
| Al-Rehaily, AJ | 1 |
| Mehmood, MH | 1 |
| Alkharfy, KM | 1 |
| Saito, T | 1 |
| Mizutani, F | 1 |
| Iwanaga, Y | 1 |
| Morikawa, K | 1 |
| Kato, H | 1 |
| Pascual, D | 1 |
| Girón, R | 1 |
| Alsasua, A | 1 |
| Benhamú, B | 1 |
| López-Rodríguez, ML | 1 |
| Martín, MI | 1 |
| Rufo, PA | 1 |
| Lin, PW | 1 |
| Andrade, A | 1 |
| Jiang, L | 1 |
| Rameh, L | 1 |
| Flexner, C | 1 |
| Alper, SL | 1 |
| Lencer, WI | 1 |
| Hoque, KM | 1 |
| Rajendran, VM | 1 |
| Binder, HJ | 1 |
| Raoof, M | 1 |
| Ghayur, MN | 1 |
| Siddiqui, BS | 1 |
| Vohra, W | 1 |
| Begum, S | 1 |
| Izzo, AA | 1 |
| Mascolo, N | 1 |
| Di Carlo, G | 1 |
| Capasso, F | 1 |
| Sandle, GI | 1 |
| McNicholas, CM | 1 |
| Lomax, RB | 1 |
| Ball, JM | 1 |
| Tian, P | 1 |
| Zeng, CQ | 1 |
| Morris, AP | 1 |
| Estes, MK | 1 |
| Kahn, ME | 1 |
| Senderowicz, A | 1 |
| Sausville, EA | 1 |
| Chang, N | 1 |
| Uribe, JM | 1 |
| Keely, SJ | 1 |
| Calandrella, S | 1 |
| Mir, GN | 1 |
| Alioto, RL | 1 |
| Sperow, JW | 1 |
| Eash, JR | 1 |
| Krebs, JB | 1 |
| Yelnosky, J | 1 |
| Young, A | 1 |
| Levin, RJ | 1 |
| Fondacaro, JD | 2 |
| Kolpak, DC | 1 |
| Burnham, DB | 1 |
| McCafferty, GP | 1 |
| Schwartz, CJ | 1 |
| Kimberg, DV | 1 |
| Sheerin, HE | 1 |
| Field, M | 1 |
| Said, SI | 1 |
| Foley, DJ | 1 |
| McPhillips, JJ | 1 |
| Eakins, K | 1 |
| Ritchie, JA | 1 |
1 review available for carbachol and Diarrhea
| Article | Year |
|---|---|
Intestinal ion transport and diarrheal disease.
Topics: Acid-Base Equilibrium; Adrenergic alpha-Agonists; Animals; Arachidonic Acids; Carbachol; Chlorides; | 1986 |
28 other studies available for carbachol and Diarrhea
| Article | Year |
|---|---|
Investigations of plausible pharmacodynamics supporting the antispasmodic, bronchodilator, and antidiarrheal activities of Berberis lycium Royle. Via in silico, in vitro, and in vivo studies.
Topics: Animals; Antidiarrheals; Berberis; Bronchodilator Agents; Carbachol; Castor Oil; Cough; Diarrhea; Di | 2023 |
In Silico, Ex Vivo and In Vivo Studies of Roflumilast as a Potential Antidiarrheal and Antispasmodic agent: Inhibition of the PDE-4 Enzyme and Voltage-gated Ca++ ion Channels.
Topics: Aminopyridines; Animals; Antidiarrheals; Benzamides; Binding Sites; Calcium Channel Blockers; Carbac | 2020 |
Potentiation of calcium-activated chloride secretion and barrier dysfunction may underlie EGF receptor tyrosine kinase inhibitor-induced diarrhea.
Topics: Animals; Antineoplastic Agents; Calcium; Carbachol; Cell Line, Tumor; Cells, Cultured; Chlorides; Di | 2020 |
Studies on antidiarrhoeal, antispasmodic and bronchodilator activities of Operculina turpethum Linn.
Topics: Animals; Antidiarrheals; Asthma; Bronchodilator Agents; Calcium; Calcium Channel Blockers; Carbachol | 2014 |
Activation of PPARgamma by rosiglitazone attenuates intestinal Cl- secretion.
Topics: Administration, Oral; Animals; Calcium; Carbachol; Chlorides; Cholera Toxin; Colforsin; Colon; Cycli | 2009 |
Neuromedin U is necessary for normal gastrointestinal motility and is regulated by serotonin.
Topics: Animals; Carbachol; Defecation; Diarrhea; Gastrointestinal Motility; Immunohistochemistry; Intestine | 2010 |
Interferon-γ alters downstream signaling originating from epidermal growth factor receptor in intestinal epithelial cells: functional consequences for ion transport.
Topics: Animals; Carbachol; Cell Line; Diarrhea; Epidermal Growth Factor; Epithelial Cells; ErbB Receptors; | 2012 |
Mechanisms of action of zinc on rat intestinal epithelial electrogenic ion secretion: insights into its antidiarrhoeal actions.
Topics: Animals; Antidiarrheals; Calcimycin; Carbachol; Colforsin; Colon; Cytochalasin D; Diarrhea; Electric | 2012 |
Gut and airways relaxant effects of Carum roxburghianum.
Topics: Animals; Antidiarrheals; Bronchoconstriction; Bronchodilator Agents; Carbachol; Carum; Castor Oil; D | 2012 |
Mechanisms underlying the antidiarrheal, antispasmodic and bronchodilator activities of Fumaria parviflora and involvement of tissue and species specificity.
Topics: Animals; Antidiarrheals; Bronchoconstriction; Bronchodilator Agents; Calcium Channels; Carbachol; Ca | 2012 |
Species differences in the antidiarrheal and antispasmodic activities of Lepidium sativum and insight into underlying mechanisms.
Topics: Animals; Antidiarrheals; Calcium; Carbachol; Castor Oil; Cathartics; Diarrhea; Female; Guinea Pigs; | 2013 |
Laxative and anti-diarrheal activity of polycarbophil in mice and rats.
Topics: Acrylic Resins; Animals; Antidiarrheals; Carbachol; Castor Oil; Cathartics; Constipation; Defecation | 2002 |
New benzimidazole derivatives: selective and orally active 5-HT3 receptor antagonists.
Topics: 5-Hydroxytryptophan; Administration, Oral; Animals; Aza Compounds; Behavior, Animal; Benzimidazoles; | 2003 |
Diarrhea-associated HIV-1 APIs potentiate muscarinic activation of Cl- secretion by T84 cells via prolongation of cytosolic Ca2+ signaling.
Topics: Adult; Aspartic Acid Endopeptidases; Calcium Signaling; Carbachol; Cell Line; Cell Membrane; Chlorid | 2004 |
Zinc inhibits cAMP-stimulated Cl secretion via basolateral K-channel blockade in rat ileum.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Barium; Carbachol; Chlorides; Colforsin; Cyclic AMP | 2005 |
Gastrointestinal, selective airways and urinary bladder relaxant effects of Hyoscyamus niger are mediated through dual blockade of muscarinic receptors and Ca2+ channels.
Topics: Animals; Calcium Channel Blockers; Carbachol; Castor Oil; Diarrhea; Female; Guinea Pigs; Hyoscyamus; | 2008 |
NG-nitro-L-arginine methyl ester modulates intestinal secretion and motility produced by carbachol.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Body Fluids; Carbachol; Diarrhea; Dose-Response Relat | 1994 |
Potassium channels in colonic crypts.
Topics: Bucladesine; Calcium Channels; Carbachol; Chlorides; Colon; Diarrhea; Electrophysiology; Humans; In | 1994 |
Age-dependent diarrhea induced by a rotaviral nonstructural glycoprotein.
Topics: Aging; Amino Acid Sequence; Animals; Calcium; Carbachol; Chlorides; Colforsin; Diarrhea; Enterotoxin | 1996 |
Possible mechanisms of diarrheal side effects associated with the use of a novel chemotherapeutic agent, flavopiridol.
Topics: Antineoplastic Agents; Carbachol; Chloride Channels; Chlorides; Cholinergic Agonists; Colforsin; Col | 2001 |
Insulin and IGF-I inhibit calcium-dependent chloride secretion by T84 human colonic epithelial cells.
Topics: Androstadienes; Carbachol; Cells, Cultured; Chlorides; Cholinergic Agonists; Chromones; Colon; Diabe | 2001 |
In vivo antimotility and antidiarrheal activity of lidamidine hydrochloride (WHR-1142A), a novel antidiarrheal agent. Comparison with diphenoxylate and loperamide.
Topics: Amidines; Animals; Antidiarrheals; Carbachol; Charcoal; Cholera Toxin; Diarrhea; Diphenoxylate; Fece | 1978 |
Diarrhoea of famine and malnutrition: investigations using a rat model. 1. Jejunal hypersecretion induced by starvation.
Topics: Animals; Bethanechol; Bethanechol Compounds; Carbachol; Chlorides; Diarrhea; Disease Models, Animal; | 1990 |
Cecectomized rat. A model of experimental secretory diarrhea in conscious animals.
Topics: Animals; Antidiarrheals; Carbachol; Cecum; Chlorpromazine; Cholera Toxin; Clonidine; Colon; Diarrhea | 1990 |
Vasoactive intestinal peptide stimulation of adenylate cyclase and active electrolyte secretion in intestinal mucosa.
Topics: Adenylyl Cyclases; Animals; Bradykinin; Calcitonin; Carbachol; Cyclic AMP; Diarrhea; Dogs; Glucagon; | 1974 |
Response of the rat ileum, uterus and vas deferens to carbachol and acetylcholine following repeated daily administration of a cholinesterase inhibitor.
Topics: Acetylcholine; Animals; Carbachol; Cholinesterases; Diarrhea; Disulfoton; Drug Interactions; Female; | 1973 |
Prostaglandin antagonism by polymeric phosphates of phloretin and related compounds.
Topics: Animals; Aqueous Humor; Blood Pressure; Carbachol; Depression, Chemical; Diarrhea; Estradiol; Eye Pr | 1971 |
Colonic motor activity and bowel function. II. Distribution and incidence of motor activity at rest and after food and carbachol.
Topics: Aged; Barium Sulfate; Carbachol; Cineradiography; Colon; Constipation; Diarrhea; Female; Food; Gastr | 1968 |