Page last updated: 2024-11-07

carbachol and Diabetes Mellitus, Type 2

carbachol has been researched along with Diabetes Mellitus, Type 2 in 15 studies

Carbachol: A slowly hydrolyzed CHOLINERGIC AGONIST that acts at both MUSCARINIC RECEPTORS and NICOTINIC RECEPTORS.

Diabetes Mellitus, Type 2: A subclass of DIABETES MELLITUS that is not INSULIN-responsive or dependent (NIDDM). It is characterized initially by INSULIN RESISTANCE and HYPERINSULINEMIA; and eventually by GLUCOSE INTOLERANCE; HYPERGLYCEMIA; and overt diabetes. Type II diabetes mellitus is no longer considered a disease exclusively found in adults. Patients seldom develop KETOSIS but often exhibit OBESITY.

Research Excerpts

ExcerptRelevanceReference
"This diet induces a type 2 diabetes/metabolic syndrome phenotype with hypertension."1.48Characterization of vascular dysregulation in meriones shawi after high-calorie diet feeding. ( Cherkaoui-Tangi, K; Lyoussi, B; Morel, N; Wibo, M, 2018)
"Insulin resistance is followed by an islet adaptation resulting in a compensating increase in insulin secretion and hyperinsulinemia."1.31Islet phospholipase A(2) activation is potentiated in insulin resistant mice. ( Ahrén, B; Karlsson, S; Simonsson, E, 2000)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (20.00)18.2507
2000's4 (26.67)29.6817
2010's7 (46.67)24.3611
2020's1 (6.67)2.80

Authors

AuthorsStudies
Liu, Y1
Jansen, HJ1
Krishnaswamy, PS1
Bogachev, O1
Rose, RA1
Lyoussi, B1
Cherkaoui-Tangi, K1
Morel, N1
Wibo, M1
Klee, NS1
Moreland, RS2
Kendig, DM2
Zhao, J1
Chen, P1
Gregersen, H1
Ets, HK1
Nobe, K1
Yamazaki, T1
Tsumita, N1
Hashimoto, T1
Honda, K1
Healy, JA1
Nilsson, KR1
Hohmeier, HE1
Berglund, J1
Davis, J1
Hoffman, J1
Kohler, M1
Li, LS1
Berggren, PO1
Newgard, CB1
Bennett, V1
Ribeiro, RA1
Batista, TM1
Coelho, FM1
Boschero, AC1
Lopes, GS1
Carneiro, EM1
Bonal, CB1
Baronnier, DE1
Pot, C1
Benkhoucha, M1
Schwab, ME1
Lalive, PH1
Herrera, PL1
Yono, M1
Latifpour, J1
Yoshida, M1
Ueda, S1
Ito, I1
Jarajapu, YP1
Guberski, DL1
Grant, MB1
Knot, HJ1
Zawalich, WS1
Kelley, GG1
Lang, E1
Spitzer, A1
Claus, D1
Neundörfer, B1
Handwerker, HO1
Simonsson, E1
Karlsson, S1
Ahrén, B1
Soulié, ML1
Cros, G1
Serrano, JJ1
Bali, JP1

Reviews

1 review available for carbachol and Diabetes Mellitus, Type 2

ArticleYear
The pathogenesis of NIDDM: the role of the pancreatic beta cell.
    Diabetologia, 1995, Volume: 38, Issue:8

    Topics: Animals; Carbachol; Cholinergic Agents; Diabetes Mellitus; Diabetes Mellitus, Type 2; Glucose; Human

1995

Other Studies

14 other studies available for carbachol and Diabetes Mellitus, Type 2

ArticleYear
Impaired regulation of heart rate and sinoatrial node function by the parasympathetic nervous system in type 2 diabetic mice.
    Scientific reports, 2021, 06-14, Volume: 11, Issue:1

    Topics: Animals; Carbachol; Cholinergic Agonists; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Disease

2021
Characterization of vascular dysregulation in meriones shawi after high-calorie diet feeding.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 2018, Volume: 40, Issue:4

    Topics: Animals; Aorta; Arginine; Carbachol; Diabetes Mellitus, Type 2; Diazoxide; Endothelium, Vascular; En

2018
Detrusor contractility to parasympathetic mediators is differentially altered in the compensated and decompensated states of diabetic bladder dysfunction.
    American journal of physiology. Renal physiology, 2019, 08-01, Volume: 317, Issue:2

    Topics: Adenosine Triphosphate; Animals; Carbachol; Cholinergic Agonists; Diabetes Mellitus, Experimental; D

2019
Stress-strain analysis of jejunal contractility in response to flow and ramp distension in type 2 diabetic GK rats: effect of carbachol stimulation.
    Journal of biomechanics, 2013, Sep-27, Volume: 46, Issue:14

    Topics: Animals; Carbachol; Cholinergic Agonists; Diabetes Mellitus, Type 2; Elastic Modulus; Gastrointestin

2013
Effect of type II diabetes on male rat bladder contractility.
    American journal of physiology. Renal physiology, 2016, 05-01, Volume: 310, Issue:9

    Topics: Adenosine Triphosphate; Aging; Animals; Carbachol; Diabetes Mellitus, Type 2; Electric Stimulation;

2016
Glucose-dependent enhancement of diabetic bladder contraction is associated with a rho kinase-regulated protein kinase C pathway.
    The Journal of pharmacology and experimental therapeutics, 2009, Volume: 328, Issue:3

    Topics: Animals; Blood Glucose; Carbachol; Cholesterol; Diabetes Mellitus, Type 2; Fatty Acids, Nonesterifie

2009
Cholinergic augmentation of insulin release requires ankyrin-B.
    Science signaling, 2010, Mar-16, Volume: 3, Issue:113

    Topics: Animals; Ankyrins; Calcium; Carbachol; Diabetes Mellitus, Type 2; Glucose; Immunoblotting; Inositol

2010
Decreased β-cell insulin secretory function in aged rats due to impaired Ca(2+) handling.
    Experimental physiology, 2012, Volume: 97, Issue:9

    Topics: Aging; Animals; Blood Glucose; Calcium; Carbachol; Cyclic AMP-Dependent Protein Kinases; Diabetes Me

2012
Nogo-A downregulation improves insulin secretion in mice.
    Diabetes, 2013, Volume: 62, Issue:5

    Topics: Animals; Antibodies, Neutralizing; Carbachol; Cholinergic Agonists; Diabetes Mellitus, Type 2; Down-

2013
Age-related alterations in the biochemical and functional properties of the bladder in type 2 diabetic GK rats.
    Journal of receptor and signal transduction research, 2005, Volume: 25, Issue:3

    Topics: Acetylcholine; Adenosine Triphosphate; Aging; Animals; Body Weight; Carbachol; Diabetes Complication

2005
Myogenic tone and reactivity of rat ophthalmic artery in acute exposure to high glucose and in a type II diabetic model.
    Investigative ophthalmology & visual science, 2006, Volume: 47, Issue:2

    Topics: Angiography; Animals; Carbachol; Cytochrome P-450 Enzyme Inhibitors; Diabetes Mellitus, Type 2; Endo

2006
Stimulation of sudomotor axon reflex mechanism by carbachol in healthy subjects and patients suffering from diabetic polyneuropathy.
    Acta neurologica Scandinavica, 1995, Volume: 91, Issue:4

    Topics: Adult; Axons; Carbachol; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Neuropathies

1995
Islet phospholipase A(2) activation is potentiated in insulin resistant mice.
    Biochemical and biophysical research communications, 2000, Jun-07, Volume: 272, Issue:2

    Topics: Animals; Arachidonic Acid; Blood Glucose; Body Weight; Carbachol; Diabetes Mellitus, Type 2; Dietary

2000
Impairment of contractile response to carbachol and muscarinic receptor coupling in gastric antral smooth muscle cells isolated from diabetic streptozotocin-treated rats and db/db mice.
    Molecular and cellular biochemistry, 1992, Feb-12, Volume: 109, Issue:2

    Topics: Animals; Carbachol; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Disease Models, Anim

1992