carbachol has been researched along with Diabetes Mellitus, Type 1 in 10 studies
Carbachol: A slowly hydrolyzed CHOLINERGIC AGONIST that acts at both MUSCARINIC RECEPTORS and NICOTINIC RECEPTORS.
Diabetes Mellitus, Type 1: A subtype of DIABETES MELLITUS that is characterized by INSULIN deficiency. It is manifested by the sudden onset of severe HYPERGLYCEMIA, rapid progression to DIABETIC KETOACIDOSIS, and DEATH unless treated with insulin. The disease may occur at any age, but is most common in childhood or adolescence.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We used the Akita mouse model of type 1 diabetes to study the effects of the parasympathetic agonist carbachol (CCh) on SAN function using intracardiac programmed stimulation, high resolution optical mapping and patch-clamping of SAN myocytes." | 1.42 | Altered parasympathetic nervous system regulation of the sinoatrial node in Akita diabetic mice. ( Azer, J; Bogachev, O; Egom, EE; Jansen, HJ; Krishnaswamy, PS; Mackasey, M; Moghtadaei, M; Robbins, C; Rose, RA, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (10.00) | 18.7374 |
| 1990's | 5 (50.00) | 18.2507 |
| 2000's | 1 (10.00) | 29.6817 |
| 2010's | 3 (30.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Krishnaswamy, PS | 1 |
| Egom, EE | 1 |
| Moghtadaei, M | 1 |
| Jansen, HJ | 1 |
| Azer, J | 1 |
| Bogachev, O | 1 |
| Mackasey, M | 1 |
| Robbins, C | 1 |
| Rose, RA | 1 |
| Chang, XW | 1 |
| Qin, Y | 1 |
| Jin, Z | 1 |
| Xi, TF | 1 |
| Yang, X | 1 |
| Lu, ZH | 1 |
| Tang, YP | 1 |
| Cai, WT | 1 |
| Chen, SJ | 1 |
| Xie, DP | 1 |
| Szasz, T | 1 |
| Wenceslau, CF | 1 |
| Burgess, B | 1 |
| Nunes, KP | 1 |
| Webb, RC | 1 |
| Park, HJ | 1 |
| Zhang, Y | 1 |
| Du, C | 1 |
| Welzig, CM | 1 |
| Madias, C | 1 |
| Aronovitz, MJ | 1 |
| Georgescu, SP | 1 |
| Naggar, I | 1 |
| Wang, B | 1 |
| Kim, YB | 1 |
| Blaustein, RO | 1 |
| Karas, RH | 1 |
| Liao, R | 1 |
| Mathews, CE | 1 |
| Galper, JB | 1 |
| Lang, E | 1 |
| Spitzer, A | 1 |
| Claus, D | 1 |
| Neundörfer, B | 1 |
| Handwerker, HO | 1 |
| Elliott, TG | 1 |
| Cockcroft, JR | 1 |
| Groop, PH | 1 |
| Viberti, GC | 1 |
| Ritter, JM | 2 |
| Yamamoto, H | 1 |
| Sims, NE | 1 |
| Macauley, SP | 1 |
| Nguyen, KH | 1 |
| Nakagawa, Y | 1 |
| Humphreys-Beher, MG | 1 |
| Takahashi, T | 1 |
| Kojima, Y | 1 |
| Tsunoda, Y | 1 |
| Beyer, LA | 1 |
| Kamijo, M | 1 |
| Sima, AA | 1 |
| Owyang, C | 1 |
| Halkin, A | 1 |
| Benjamin, N | 1 |
| Doktor, HS | 1 |
| Todd, SD | 1 |
| Viberti, G | 1 |
| Villa, MP | 1 |
| Cacciari, E | 1 |
| Bernardi, F | 1 |
| Cicognani, A | 1 |
| Salardi, S | 1 |
| Zapulla, F | 1 |
10 other studies available for carbachol and Diabetes Mellitus, Type 1
| Article | Year |
|---|---|
Altered parasympathetic nervous system regulation of the sinoatrial node in Akita diabetic mice.
Topics: Acetylcholine; Action Potentials; Animals; Carbachol; Cardiotonic Agents; Diabetes Mellitus, Experim | 2015 |
Interleukin-6 (IL-6) mediated the increased contraction of distal colon in streptozotocin-induced diabetes in rats via IL-6 receptor pathway.
Topics: Animals; Carbachol; Colon; Cytokine Receptor gp130; Diabetes Mellitus, Experimental; Diabetes Mellit | 2015 |
Toll-Like Receptor 4 Activation Contributes to Diabetic Bladder Dysfunction in a Murine Model of Type 1 Diabetes.
Topics: Animals; Carbachol; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetic Nephropathi | 2016 |
Role of SREBP-1 in the development of parasympathetic dysfunction in the hearts of type 1 diabetic Akita mice.
Topics: Animals; Carbachol; Cells, Cultured; Chick Embryo; Cholinergic Agents; Diabetes Mellitus, Type 1; Di | 2009 |
Stimulation of sudomotor axon reflex mechanism by carbachol in healthy subjects and patients suffering from diabetic polyneuropathy.
Topics: Adult; Axons; Carbachol; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Neuropathies | 1995 |
Inhibition of nitric oxide synthesis in forearm vasculature of insulin-dependent diabetic patients: blunted vasoconstriction in patients with microalbuminuria.
Topics: Adult; Albuminuria; Arginine; Carbachol; Diabetes Mellitus, Type 1; Female; Forearm; Humans; Male; M | 1993 |
Alterations in the secretory response of non-obese diabetic (NOD) mice to muscarinic receptor stimulation.
Topics: Animals; Autoantibodies; Base Sequence; Carbachol; Cyclic AMP; Diabetes Mellitus, Type 1; Mice; Mice | 1996 |
Impaired intracellular signal transduction in gastric smooth muscle of diabetic BB/W rats.
Topics: Acetylcholine; Animals; Calcium; Carbachol; Cell Membrane; Cells, Cultured; Cytosol; Diabetes Mellit | 1996 |
Vascular responsiveness and cation exchange in insulin-dependent diabetes.
Topics: Adult; Angiotensin II; Biological Transport, Active; Carbachol; Cations; Diabetes Mellitus, Type 1; | 1991 |
Bronchial reactivity in diabetic patients. Relationship to duration of diabetes and degree of glycemic control.
Topics: Adolescent; Asthma; Bronchial Provocation Tests; Carbachol; Child; Diabetes Mellitus, Type 1; Female | 1988 |