carbachol has been researched along with Dementia in 4 studies
Carbachol: A slowly hydrolyzed CHOLINERGIC AGONIST that acts at both MUSCARINIC RECEPTORS and NICOTINIC RECEPTORS.
Dementia: An acquired organic mental disorder with loss of intellectual abilities of sufficient severity to interfere with social or occupational functioning. The dysfunction is multifaceted and involves memory, behavior, personality, judgment, attention, spatial relations, language, abstract thought, and other executive functions. The intellectual decline is usually progressive, and initially spares the level of consciousness.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Young males showed greater responsiveness to both drugs than young females, this being reflected in higher maxima of the dose-response curves obtained for the males." | 5.27 | The responsiveness of human eccrine sweat glands to choline and carbachol. Application to the study of peripheral cholinergic functioning in Alzheimer-type dementia. ( Bradshaw, CM; Lamb, K; Szabadi, E, 1983) |
| "The relative proportion of super-high, high and low affinity agonist binding sites was measured in the hippocampus from individuals with dementia of the Alzheimer type (AD/SDAT), mixed (AD-MID) type and controls, using labelled quinuclidinyl benzilate ([3H]QNB) competing with unlabelled carbachol." | 3.67 | Muscarinic receptor subtypes in hippocampus in Alzheimer's disease and mixed dementia type. ( Alafuzoff, I; Nordberg, A; Winblad, B, 1986) |
| " Young males showed greater responsiveness to both drugs than young females, this being reflected in higher maxima of the dose-response curves obtained for the males." | 1.27 | The responsiveness of human eccrine sweat glands to choline and carbachol. Application to the study of peripheral cholinergic functioning in Alzheimer-type dementia. ( Bradshaw, CM; Lamb, K; Szabadi, E, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (50.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Warren, NM | 1 |
| Piggott, MA | 1 |
| Lees, AJ | 1 |
| Perry, EK | 2 |
| Burn, DJ | 1 |
| Lamb, K | 1 |
| Bradshaw, CM | 1 |
| Szabadi, E | 1 |
| Smith, CJ | 1 |
| Court, JA | 1 |
| Perry, RH | 1 |
| Nordberg, A | 1 |
| Alafuzoff, I | 1 |
| Winblad, B | 1 |
4 other studies available for carbachol and Dementia
| Article | Year |
|---|---|
Intact coupling of M1 receptors and preserved M2 and M4 receptors in the cortex in progressive supranuclear palsy: contrast with other dementias.
Topics: Alzheimer Disease; Atropine; Autoradiography; Carbachol; Cerebral Cortex; Dementia; Humans; Lewy Bod | 2008 |
The responsiveness of human eccrine sweat glands to choline and carbachol. Application to the study of peripheral cholinergic functioning in Alzheimer-type dementia.
Topics: Adult; Aged; Aging; Alzheimer Disease; Carbachol; Choline; Dementia; Dose-Response Relationship, Dru | 1983 |
Cholinergic nicotinic and muscarinic receptors in dementia of Alzheimer, Parkinson and Lewy body types.
Topics: Adult; Aged; Aged, 80 and over; Alzheimer Disease; Brain Chemistry; Carbachol; Choline O-Acetyltrans | 1990 |
Muscarinic receptor subtypes in hippocampus in Alzheimer's disease and mixed dementia type.
Topics: Aged; Alzheimer Disease; Carbachol; Dementia; Female; Hippocampus; Humans; Male; Quinuclidinyl Benzi | 1986 |