carbachol has been researched along with Colitis in 36 studies
Carbachol: A slowly hydrolyzed CHOLINERGIC AGONIST that acts at both MUSCARINIC RECEPTORS and NICOTINIC RECEPTORS.
Colitis: Inflammation of the COLON section of the large intestine (INTESTINE, LARGE), usually with symptoms such as DIARRHEA (often with blood and mucus), ABDOMINAL PAIN, and FEVER.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Carbachol-induced contraction of the rat colon is impaired in rats with trinitrobenzene sulfonic acid (TNBS)-induced colitis." | 7.77 | Colonic inflammation increases the contribution of muscarinic M2 receptors to carbachol-induced contraction of the rat colon. ( Jragh, DM; Khan, I; Oriowo, MA, 2011) |
| " Our aim was to evaluate changes in secretory responses to cholinergic agonist carbachol in distal and proximal colon during colitis development, regarding secretory activity of enteric nervous system (ENS) and prostaglandins." | 7.77 | The early effect of dextran sodium sulfate administration on carbachol-induced short-circuit current in distal and proximal colon during colitis development. ( Hock, M; Kment, M; Pácha, J; Soták, M, 2011) |
| "To investigate the effect of curcumin on colitis-induced reduction of carbachol-induced contraction in colon segments from rats treated with trinitrobenzenesulphonic acid." | 7.75 | Curcumin reverses attenuated carbachol-induced contraction of the colon in a rat model of colitis. ( Khan, I; Lubbad, AS; Oriowo, MA, 2009) |
| "Colitis was induced by intracolonic instillation of 4% acetic acid." | 5.32 | Electroacupuncture ameliorates experimental colitis induced by acetic acid in rat. ( Kang, JW; Kim, HJ; Kim, JY; Kim, TW; Kwon, YB; La, JH; Sung, TS; Yang, IS, 2004) |
| " Inhibitory effect of nifedipine against cholinergic contractions, blunted in acetic acid-induced colitis, was also recovered in MC-treated rats." | 3.80 | Antispasmodic and myorelaxant effects of the flavoring agent methyl cinnamate in gut: potential inhibition of tyrosine kinase. ( Aragão, KS; Brito, TS; Cosker, F; Lahlou, S; Lima, FJ; Magalhães, PJ; Ribeiro-Filho, HV; Santos, AA; Silva, CM; Souza, MH, 2014) |
| "Carbachol-induced contraction of the rat colon is impaired in rats with trinitrobenzene sulfonic acid (TNBS)-induced colitis." | 3.77 | Colonic inflammation increases the contribution of muscarinic M2 receptors to carbachol-induced contraction of the rat colon. ( Jragh, DM; Khan, I; Oriowo, MA, 2011) |
| "Colitis was induced in rats by 2,4-dinitrobenzenesulfonic acid." | 3.76 | Control of enteric neuromuscular functions by purinergic A(3) receptors in normal rat distal colon and experimental bowel inflammation. ( Antonioli, L; Awwad, O; Bin, A; Blandizzi, C; Castagliuolo, I; Colucci, R; Fornai, M; Gaion, RM; Ghisu, N; Giron, MC; Tuccori, M; Zoppellaro, C, 2010) |
| "To investigate the effect of curcumin on colitis-induced reduction of carbachol-induced contraction in colon segments from rats treated with trinitrobenzenesulphonic acid." | 3.75 | Curcumin reverses attenuated carbachol-induced contraction of the colon in a rat model of colitis. ( Khan, I; Lubbad, AS; Oriowo, MA, 2009) |
| "The impact of colitis on uterine contractility and estrous cycle was investigated after intracolonic administration of 2,4,6-trinitrobenzenesulfonic acid (TNBS) in rats." | 3.73 | Uterine motor alterations and estrous cycle disturbances associated with colonic inflammation in the rat. ( Bueno, L; Fioramonti, J; Houdeau, E; Larauche, M; Monnerie, R, 2005) |
| " Smooth muscle relaxation was obtained by salbutamol and l-phenylephrine, whereas contraction was achieved by carbachol and 1-(3-chlorophenyl)-biguanide." | 3.72 | Effect of pharmacologically induced smooth muscle activation on permeability in murine colitis. ( Garrelds, IM; Meijssen, MA; van Meeteren, ME; Zijlstra, FJ, 2003) |
| " We used video microscopy to study the contractility of circular smooth muscle cells (CSMC) isolated from the rat mid-descending colon throughout the course of TNBS-induced colitis, measuring their shortening response to carbachol (CCh), 5-HT, histamine or high K(+)." | 3.72 | Persistent and selective effects of inflammation on smooth muscle cell contractility in rat colitis. ( Blennerhassett, MG; Wells, RW, 2004) |
| "Distal colitis was induced by intrarectal administration of trinitrobenzene sulfonic, acetic acid, or Trichinella spiralis larvae, or by intraperitoneal injection of mitomycin C." | 3.68 | On the specificity of altered muscle function in experimental colitis in rats. ( Collins, SM; Grossi, L; McHugh, K, 1993) |
| "Colitis was induced in BALB/c mice by provision of 5% dextran sodium sulfate (DSS) for 7 days." | 1.38 | The contribution of protein kinase C and CPI-17 signaling pathways to hypercontractility in murine experimental colitis. ( Chappellaz, M; Ihara, E; MacDonald, JA; Turner, SR, 2012) |
| "Colitis was induced in male Sprague-Dawley rats by intra-rectal instillation of trinitrobenzenesulphonic acid (TNBS)." | 1.38 | Expression of alternatively spliced variants of Na-Ca-exchanger-1 in experimental colitis: role in reduced colonic contractility. ( Khan, I; Oriowo, MA; Shubair, M, 2012) |
| "Colitis was induced in BALB/c mice by providing 5% dextran sulfate sodium (DSS) in drinking water for 7 days." | 1.35 | Mitogen-activated protein kinase pathways contribute to hypercontractility and increased Ca2+ sensitization in murine experimental colitis. ( Beck, PL; Chappellaz, M; Ihara, E; MacDonald, JA; Medlicott, SA; Wong, J, 2009) |
| "Colitis was confirmed using gross morphology, histology, and measurements of myeloperoxidase activity." | 1.34 | Changes in urinary bladder smooth muscle function in response to colonic inflammation. ( Akbarali, H; Foreman, RD; Greenwood-Van Meerveld, B; Malykhina, A; Noronha, R, 2007) |
| "Colitis was induced in Sprague-Dawley male rats by intra-colonic instillation of trinitrobenzenesulphonic acid (TNBS; 40 mg/rat in 50 ethanol)." | 1.33 | Mechanism underlying the reversal of contractility dysfunction in experimental colitis by cyclooxygenase-2 inhibition. ( Khan, I; Oriowo, MA, 2006) |
| "Colitis was induced by intracolonic instillation of 4% acetic acid." | 1.32 | Electroacupuncture ameliorates experimental colitis induced by acetic acid in rat. ( Kang, JW; Kim, HJ; Kim, JY; Kim, TW; Kwon, YB; La, JH; Sung, TS; Yang, IS, 2004) |
| "Colitis was induced in rats by intrarectal administration of trinitrobenzenesulfonic acid in ethanol." | 1.31 | Colitis-induced alterations in adrenergic control of circular smooth muscle in vitro in rats. ( Bossone, C; Piñeiro-Carrero, V; Shea-Donohue, T; Zhao, A, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (2.78) | 18.7374 |
| 1990's | 6 (16.67) | 18.2507 |
| 2000's | 20 (55.56) | 29.6817 |
| 2010's | 9 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lee, B | 1 |
| Hong, GS | 1 |
| Lee, SH | 1 |
| Kim, H | 1 |
| Kim, A | 1 |
| Hwang, EM | 1 |
| Kim, J | 1 |
| Lee, MG | 1 |
| Yang, JY | 1 |
| Kweon, MN | 1 |
| Tse, CM | 1 |
| Mark, D | 1 |
| Oh, U | 1 |
| Lima, FJ | 1 |
| Cosker, F | 1 |
| Brito, TS | 1 |
| Ribeiro-Filho, HV | 1 |
| Silva, CM | 1 |
| Aragão, KS | 1 |
| Lahlou, S | 1 |
| Souza, MH | 1 |
| Santos, AA | 1 |
| Magalhães, PJ | 1 |
| Lubbad, AS | 1 |
| Oriowo, MA | 6 |
| Khan, I | 6 |
| Ihara, E | 2 |
| Beck, PL | 1 |
| Chappellaz, M | 2 |
| Wong, J | 1 |
| Medlicott, SA | 1 |
| MacDonald, JA | 2 |
| Antonioli, L | 1 |
| Fornai, M | 1 |
| Colucci, R | 1 |
| Ghisu, N | 1 |
| Tuccori, M | 1 |
| Awwad, O | 1 |
| Bin, A | 1 |
| Zoppellaro, C | 1 |
| Castagliuolo, I | 1 |
| Gaion, RM | 1 |
| Giron, MC | 1 |
| Blandizzi, C | 1 |
| Asfaw, TS | 1 |
| Hypolite, J | 1 |
| Northington, GM | 1 |
| Arya, LA | 1 |
| Wein, AJ | 1 |
| Malykhina, AP | 1 |
| Jragh, DM | 1 |
| Hock, M | 1 |
| Soták, M | 1 |
| Kment, M | 1 |
| Pácha, J | 1 |
| Turner, SR | 1 |
| Shubair, M | 1 |
| Aldini, R | 1 |
| Budriesi, R | 1 |
| Roda, G | 1 |
| Micucci, M | 1 |
| Ioan, P | 1 |
| D'Errico-Grigioni, A | 1 |
| Sartini, A | 1 |
| Guidetti, E | 1 |
| Marocchi, M | 1 |
| Cevenini, M | 1 |
| Rosini, F | 1 |
| Montagnani, M | 1 |
| Chiarini, A | 1 |
| Mazzella, G | 1 |
| Sánchez de Medina, F | 1 |
| Pérez, R | 1 |
| Martínez-Augustin, O | 1 |
| González, R | 1 |
| Lorente, MD | 1 |
| Gálvez, J | 1 |
| Zarzuelo, A | 1 |
| Zijlstra, FJ | 2 |
| van Meeteren, ME | 1 |
| Garrelds, IM | 1 |
| Meijssen, MA | 1 |
| Wells, RW | 1 |
| Blennerhassett, MG | 1 |
| Kang, JW | 1 |
| Kim, TW | 1 |
| La, JH | 1 |
| Sung, TS | 1 |
| Kim, HJ | 1 |
| Kwon, YB | 1 |
| Kim, JY | 1 |
| Yang, IS | 1 |
| Houdeau, E | 1 |
| Larauche, M | 1 |
| Monnerie, R | 1 |
| Bueno, L | 1 |
| Fioramonti, J | 1 |
| Sato, K | 2 |
| Ninomiya, H | 1 |
| Ohkura, S | 2 |
| Ozaki, H | 2 |
| Nasu, T | 2 |
| Al-Jarallah, A | 2 |
| Skinn, AC | 1 |
| Vergnolle, N | 1 |
| Zamuner, SR | 1 |
| Wallace, JL | 1 |
| Cellars, L | 1 |
| MacNaughton, WK | 1 |
| Sherman, PM | 1 |
| Kitahara, Y | 1 |
| Ohama, T | 1 |
| Hori, M | 1 |
| Sato, M | 1 |
| Kobayashi, S | 1 |
| Sasaki, Y | 1 |
| Hayashi, T | 1 |
| Noronha, R | 1 |
| Akbarali, H | 1 |
| Malykhina, A | 1 |
| Foreman, RD | 1 |
| Greenwood-Van Meerveld, B | 2 |
| Krimi, RB | 1 |
| Kotelevets, L | 1 |
| Dubuquoy, L | 1 |
| Plaisancié, P | 1 |
| Walker, F | 1 |
| Lehy, T | 1 |
| Desreumaux, P | 1 |
| Van Seuningen, I | 1 |
| Chastre, E | 1 |
| Forgue-Lafitte, ME | 1 |
| Marie, JC | 1 |
| Kachur, JF | 1 |
| Keshavarzian, A | 1 |
| Sundaresan, R | 1 |
| Doria, M | 1 |
| Walsh, R | 1 |
| de las Alas, MM | 1 |
| Gaginella, TS | 1 |
| Grossi, L | 1 |
| McHugh, K | 1 |
| Collins, SM | 1 |
| McKay, DM | 2 |
| Singh, PK | 1 |
| Boyer, JC | 1 |
| Guitton, C | 1 |
| Pignodel, C | 1 |
| Cuq, P | 1 |
| Moussu, P | 1 |
| Pouderoux, P | 1 |
| Christen, MO | 1 |
| Balmes, JL | 1 |
| Bali, JP | 1 |
| van Bergeijk, JD | 1 |
| van Westreenen, H | 1 |
| Adhien, P | 1 |
| Ferrary, E | 1 |
| Cohen-Tannoudji, M | 1 |
| Pehau-Arnaudet, G | 1 |
| Lapillonne, A | 1 |
| Athman, R | 1 |
| Ruiz, T | 1 |
| Boulouha, L | 1 |
| El Marjou, F | 1 |
| Doye, A | 1 |
| Fontaine, JJ | 1 |
| Antony, C | 1 |
| Babinet, C | 1 |
| Louvard, D | 1 |
| Jaisser, F | 1 |
| Robine, S | 1 |
| Venkova, K | 1 |
| Dunn, ST | 1 |
| Adesina, AM | 1 |
| Zhao, A | 1 |
| Bossone, C | 1 |
| Piñeiro-Carrero, V | 1 |
| Shea-Donohue, T | 1 |
| Dublineau, I | 1 |
| Morel, E | 1 |
| Griffiths, NM | 1 |
| Börjesson, L | 1 |
| Aldenborg, F | 1 |
| Delbro, DS | 1 |
| Sayer, B | 1 |
| Lu, J | 1 |
| Green, C | 1 |
| Söderholm, JD | 1 |
| Akhtar, M | 1 |
| Smith, B | 1 |
| Butler, M | 1 |
36 other studies available for carbachol and Colitis
| Article | Year |
|---|---|
Anoctamin 1/TMEM16A controls intestinal Cl
Topics: Animals; Anoctamin-1; Calcium; Carbachol; Chloride Channels; Chlorides; Cholera Toxin; Colitis; Fema | 2019 |
Antispasmodic and myorelaxant effects of the flavoring agent methyl cinnamate in gut: potential inhibition of tyrosine kinase.
Topics: Acetic Acid; Animals; Calcium; Calcium Channel Blockers; Carbachol; Cinnamates; Colitis; Colon; Duod | 2014 |
Curcumin reverses attenuated carbachol-induced contraction of the colon in a rat model of colitis.
Topics: Animals; Carbachol; Colitis; Colon; Curcumin; Disease Models, Animal; Male; Muscle Contraction; NF-k | 2009 |
Mitogen-activated protein kinase pathways contribute to hypercontractility and increased Ca2+ sensitization in murine experimental colitis.
Topics: Animals; Calcium; Carbachol; Colitis; Colon; Cytokines; Dextran Sulfate; Extracellular Signal-Regula | 2009 |
Control of enteric neuromuscular functions by purinergic A(3) receptors in normal rat distal colon and experimental bowel inflammation.
Topics: Adenosine; Adenosine Deaminase; Animals; Benzenesulfonates; Carbachol; Colitis; Colon; Disease Model | 2010 |
Acute colonic inflammation triggers detrusor instability via activation of TRPV1 receptors in a rat model of pelvic organ cross-sensitization.
Topics: Acute Disease; Animals; Carbachol; Cholinergic Agents; Colitis; Diterpenes; Electric Stimulation; Ma | 2011 |
Colonic inflammation increases the contribution of muscarinic M2 receptors to carbachol-induced contraction of the rat colon.
Topics: Animals; Carbachol; Colitis; Colon; Diamines; Disease Models, Animal; Inflammation; Isometric Contra | 2011 |
The early effect of dextran sodium sulfate administration on carbachol-induced short-circuit current in distal and proximal colon during colitis development.
Topics: Animals; Carbachol; Colitis; Colon; Dextran Sulfate; Enteric Nervous System; Intestinal Mucosa; Male | 2011 |
The contribution of protein kinase C and CPI-17 signaling pathways to hypercontractility in murine experimental colitis.
Topics: Animals; Carbachol; Cholinergic Agonists; Colitis; Colon; Female; Intracellular Signaling Peptides a | 2012 |
Expression of alternatively spliced variants of Na-Ca-exchanger-1 in experimental colitis: role in reduced colonic contractility.
Topics: Alternative Splicing; Animals; Blotting, Western; Carbachol; Colitis; Colon; Gastrointestinal Motili | 2012 |
Curcuma longa extract exerts a myorelaxant effect on the ileum and colon in a mouse experimental colitis model, independent of the anti-inflammatory effect.
Topics: Animals; Anti-Arrhythmia Agents; Anti-Inflammatory Agents; Atropine; Carbachol; Cardiotonic Agents; | 2012 |
Disturbances of colonic ion secretion in inflammation: role of the enteric nervous system and cAMP.
Topics: 1-Methyl-3-isobutylxanthine; Anesthetics, Local; Animals; Biological Transport; Carbachol; Cholinerg | 2002 |
Effect of pharmacologically induced smooth muscle activation on permeability in murine colitis.
Topics: Albuterol; Animals; Biguanides; Carbachol; Colitis; Dextran Sulfate; Disease Models, Animal; Female; | 2003 |
Persistent and selective effects of inflammation on smooth muscle cell contractility in rat colitis.
Topics: Animals; Carbachol; Cells, Cultured; Cholinergic Agonists; Colitis; Dose-Response Relationship, Drug | 2004 |
Electroacupuncture ameliorates experimental colitis induced by acetic acid in rat.
Topics: Acetic Acid; Adrenergic beta-Antagonists; Animals; Carbachol; Cholinergic Agonists; Colitis; Electro | 2004 |
Uterine motor alterations and estrous cycle disturbances associated with colonic inflammation in the rat.
Topics: Animals; Carbachol; Colitis; Colon; Estrus; Female; In Vitro Techniques; Muscarinic Agonists; Oxytoc | 2005 |
Impairment of PAR-2-mediated relaxation system in colonic smooth muscle after intestinal inflammation.
Topics: Animals; Apamin; Carbachol; Colitis; Colon; Dextran Sulfate; Dose-Response Relationship, Drug; In Vi | 2006 |
Mechanism underlying the reversal of contractility dysfunction in experimental colitis by cyclooxygenase-2 inhibition.
Topics: Animals; Blotting, Western; Carbachol; Colitis; Colon; Cyclooxygenase 2 Inhibitors; Disease Models, | 2006 |
Mechanism of reduced colonic contractility in experimental colitis: role of sarcoplasmic reticulum pump isoform-2.
Topics: Animals; Body Weight; Carbachol; Colitis; Dose-Response Relationship, Drug; Gastrointestinal Motilit | 2007 |
Citrobacter rodentium infection causes iNOS-independent intestinal epithelial dysfunction in mice.
Topics: Animals; Bacterial Translocation; Carbachol; Cell Membrane Permeability; Cholinergic Agonists; Citro | 2006 |
Involvement of CPI-17 downregulation in the dysmotility of the colon from dextran sodium sulphate-induced experimental colitis in a mouse model.
Topics: Animals; Anticoagulants; Blotting, Western; Carbachol; Cholinergic Agonists; Colitis; Dextran Sulfat | 2007 |
Changes in urinary bladder smooth muscle function in response to colonic inflammation.
Topics: Animals; Carbachol; Cholinergic Agonists; Colitis; Electric Stimulation; Enema; Male; Mucous Membran | 2007 |
Role of Ca2+-sensitization in attenuated carbachol-induced contraction of the colon in a rat model of colitis.
Topics: Animals; Blotting, Western; Calcium; Carbachol; Colitis; Colon; Disease Models, Animal; Gene Express | 2008 |
Resistin-like molecule beta regulates intestinal mucous secretion and curtails TNBS-induced colitis in mice.
Topics: Animals; Blotting, Western; Calcium; Carbachol; Cells, Cultured; Colitis; Gastrins; Gene Expression; | 2008 |
Colitis reduces short-circuit current response to inflammatory mediators in rat colonic mucosa.
Topics: Alprostadil; Animals; Anions; Bradykinin; Carbachol; Colitis; Intestinal Mucosa; Male; Mitomycin; Ne | 1995 |
On the specificity of altered muscle function in experimental colitis in rats.
Topics: Acetates; Acetic Acid; Animals; Carbachol; Colitis; Colon; Dose-Response Relationship, Drug; Female; | 1993 |
Superantigen activation of immune cells evokes epithelial (T84) transport and barrier abnormalities via IFN-gamma and TNF alpha: inhibition of increased permeability, but not diminished secretory responses by TGF-beta2.
Topics: Adult; Antibodies, Monoclonal; Antigens, Bacterial; Biological Transport; Carbachol; Cell Line; Cell | 1997 |
Differential responsiveness to contractile agents of isolated smooth muscle cells from human colons as a function of age and inflammation.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Carbachol; Colitis; Colon; Female; Humans; Male; Middle | 1997 |
Diminished nitroprusside-induced relaxation of inflamed colonic smooth muscle in mice.
Topics: Animals; Carbachol; Colitis; Colon; Cyclic GMP; Dextran Sulfate; Female; Mice; Mice, Inbred BALB C; | 1998 |
In vivo, villin is required for Ca(2+)-dependent F-actin disruption in intestinal brush borders.
Topics: Actin Cytoskeleton; Actins; Animals; Calcium; Carbachol; Carrier Proteins; Colitis; Culture Techniqu | 1999 |
Neuromuscular dysfunction in the jejunum and colon of human leukocyte antigen B27 transgenic rats.
Topics: Adrenergic Agents; Animals; Animals, Genetically Modified; Atropine; Carbachol; Colitis; Electric St | 2000 |
Colitis-induced alterations in adrenergic control of circular smooth muscle in vitro in rats.
Topics: Adrenergic Agonists; Adrenergic Antagonists; Animals; Carbachol; Colitis; Disease Progression; Elect | 2001 |
Characterization of altered absorptive and secretory functions in the rat colon after abdominal irradiation: comparison with the effects of total-body irradiation.
Topics: Abdomen; Animals; Carbachol; Colforsin; Colitis; Colon; Dose-Response Relationship, Drug; Electric C | 2002 |
Functional effects of dextran sulphate sodium (DSS) treatment on the longitudinal muscle of rat distal colon.
Topics: Animals; Carbachol; Cholinergic Agonists; Colitis; Colon; Dextran Sulfate; Dose-Response Relationshi | 2001 |
Dextran sodium sulphate-induced colitis perturbs muscarinic cholinergic control of colonic epithelial ion transport.
Topics: Animals; Atropine; Carbachol; Cholinergic Agonists; Colitis; Dextran Sulfate; Disease Models, Animal | 2002 |
The autonomic control of colonic mucin secretion in the mouse.
Topics: Administration, Oral; Animals; Atropine; Autonomic Nervous System; Carbachol; Colitis; Colon; Epithe | 1974 |