carbachol has been researched along with Chronic Disease in 36 studies
Carbachol: A slowly hydrolyzed CHOLINERGIC AGONIST that acts at both MUSCARINIC RECEPTORS and NICOTINIC RECEPTORS.
Chronic Disease: Diseases which have one or more of the following characteristics: they are permanent, leave residual disability, are caused by nonreversible pathological alteration, require special training of the patient for rehabilitation, or may be expected to require a long period of supervision, observation, or care (Dictionary of Health Services Management, 2d ed). For epidemiological studies chronic disease often includes HEART DISEASES; STROKE; CANCER; and diabetes (DIABETES MELLITUS, TYPE 2).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Aim of this study was to evaluate whether the carbachol test and the nerve lesions responsible for bladder dysfunction possess predictive value in patients with chronic urinary retention who undergo temporary sacral neuromodulation (PNE test)." | 7.72 | [Sacral neuromodulation in patients with nonobstructive, chronic urinary retention: relevance of the carbachol test and influence of associated nerve lession]. ( Alken, P; Braun, PM; Bross, S; Jünemann, KP; Knoll, T; Martinez Portillo, FJ; Seif, C; Weiss, J, 2003) |
| "The present study examined 15 patients previously resistant to conventional antihistamines, in which doxepin at doses in the range of 50-75 mg/day was shown to be effective in treatment of chronic urticaria and without significant adverse side effects." | 7.68 | Mechanism of action of doxepin in the treatment of chronic urticaria. ( Almeida, L; Figueiredo, A; Gonçalo, M; Poiares-Baptista, A; Ribeiro, CA; Teixeira, F, 1990) |
| "Aim of this study was to evaluate whether the carbachol test and the nerve lesions responsible for bladder dysfunction possess predictive value in patients with chronic urinary retention who undergo temporary sacral neuromodulation (PNE test)." | 3.72 | [Sacral neuromodulation in patients with nonobstructive, chronic urinary retention: relevance of the carbachol test and influence of associated nerve lession]. ( Alken, P; Braun, PM; Bross, S; Jünemann, KP; Knoll, T; Martinez Portillo, FJ; Seif, C; Weiss, J, 2003) |
| "The present study examined 15 patients previously resistant to conventional antihistamines, in which doxepin at doses in the range of 50-75 mg/day was shown to be effective in treatment of chronic urticaria and without significant adverse side effects." | 3.68 | Mechanism of action of doxepin in the treatment of chronic urticaria. ( Almeida, L; Figueiredo, A; Gonçalo, M; Poiares-Baptista, A; Ribeiro, CA; Teixeira, F, 1990) |
| "Chronic bronchitis was induced in 6 mongrel dogs by chronic exposure to SO2 gas; the degree of chronic airway obstruction and the effects on airway responsiveness to inhaled histamine, carbachol, and prostaglandin F2 alpha were examined." | 3.66 | Experimental induction of chronic bronchitis in dogs: effects on airway obstruction and responsiveness. ( Drazen, JM; Ingram, RH; O'Cain, CF, 1982) |
| " For timolol, nasolacrimal occlusion collapsed the dose-response curve and extended the duration of action." | 2.67 | Therapeutic index of pilocarpine, carbachol, and timolol with nasolacrimal occlusion. ( Fuqua, M; Nardin, GF; Sharir, M; Zimmerman, TJ, 1992) |
| "Chronic anal fissure is a tear in the lining of the anal canal that, if not treated appropriately at an early stage, causes considerable anal pain during defaecation." | 2.43 | Pharmacological advancements in the treatment of chronic anal fissure. ( Acheson, AG; Scholefield, JH, 2005) |
| "Senicapoc-treated sheep also demonstrated reduced airway hyperresponsiveness, requiring a significantly higher dose of carbachol to increase resistance by 100% compared to allergen-challenged vehicle-control sheep (20±5 vs." | 1.39 | K(Ca)3.1 channel-blockade attenuates airway pathophysiology in a sheep model of chronic asthma. ( Barcham, G; Barker, D; Bradding, P; Castle, N; Koumoundouros, E; Snibson, K; Sum, G; Van Der Velden, J; Wulff, H, 2013) |
| "To evaluate chronic hyperlipidemia on bladder function, we examined the functional and histological changes of the bladder in myocardial infarction-prone Watanabe Heritable Hyperlipidemic (WHHLMI) rabbits." | 1.36 | The effects of chronic hyperlipidemia on bladder function in myocardial infarction-prone Watanabe heritable hyperlipidemic (WHHLMI) rabbits. ( Masunaga, K; Nagata, T; Satoji, Y; Shiomi, M; Yoshida, M, 2010) |
| "Spinal cord transection was performed at the T(9)-T(10) level 2-3 weeks prior to the experiment and a microdialysis fiber was inserted in the L(6)-S(1) lumbosacral spinal cord one day before the experiments." | 1.34 | Receptor activated bladder and spinal ATP release in neurally intact and chronic spinal cord injured rats. ( Boone, TB; Gangitano, DA; Salas, NA; Smith, CP; Somogyi, GT, 2007) |
| "Acute gastroenteritis is a strong risk factor for the development of irritable bowel syndrome (IBS)." | 1.33 | Mechanisms underlying the maintenance of muscle hypercontractility in a model of postinfective gut dysfunction. ( Akiho, H; Blennerhassett, P; Collins, SM; Deng, Y; Kanbayashi, H, 2005) |
| "Patients with ulcerative colitis have abnormal rectal motility." | 1.31 | Abnormal contractile properties of rectal smooth muscle in chronic ulcerative colitis. ( Brading, AF; Cook, TA; Mortensen, NJ, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (25.00) | 18.7374 |
| 1990's | 9 (25.00) | 18.2507 |
| 2000's | 16 (44.44) | 29.6817 |
| 2010's | 2 (5.56) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Van Der Velden, J | 1 |
| Sum, G | 1 |
| Barker, D | 1 |
| Koumoundouros, E | 1 |
| Barcham, G | 1 |
| Wulff, H | 1 |
| Castle, N | 1 |
| Bradding, P | 1 |
| Snibson, K | 1 |
| Ozgür, A | 1 |
| Onol, FF | 1 |
| Ercan, F | 1 |
| Tarcan, T | 1 |
| Yoshida, M | 1 |
| Masunaga, K | 1 |
| Nagata, T | 1 |
| Satoji, Y | 1 |
| Shiomi, M | 1 |
| Roux, E | 2 |
| Duvert, M | 1 |
| Marthan, R | 2 |
| Bross, S | 1 |
| Braun, PM | 1 |
| Weiss, J | 1 |
| Martinez Portillo, FJ | 1 |
| Knoll, T | 1 |
| Seif, C | 1 |
| Jünemann, KP | 1 |
| Alken, P | 1 |
| Ziganshin, AU | 1 |
| Khaziakhmetov, DF | 1 |
| Ziganshina, LE | 1 |
| Khaziakhmetova, VN | 1 |
| Jourjikiya, RK | 1 |
| Ziganshin, BA | 1 |
| Giniyatova, LR | 1 |
| Burnstock, G | 1 |
| Popović, J | 1 |
| Krsljak, E | 1 |
| Grbović, L | 1 |
| Stojić, D | 1 |
| Akiho, H | 1 |
| Deng, Y | 1 |
| Blennerhassett, P | 1 |
| Kanbayashi, H | 1 |
| Collins, SM | 1 |
| Acheson, AG | 1 |
| Scholefield, JH | 1 |
| Dobrev, D | 2 |
| Friedrich, A | 1 |
| Voigt, N | 1 |
| Jost, N | 1 |
| Wettwer, E | 2 |
| Christ, T | 2 |
| Knaut, M | 1 |
| Ravens, U | 2 |
| Salas, NA | 1 |
| Somogyi, GT | 1 |
| Gangitano, DA | 1 |
| Boone, TB | 1 |
| Smith, CP | 1 |
| Blomfield, J | 1 |
| Settree, PJ | 1 |
| Allars, HM | 1 |
| Rush, AR | 1 |
| Drazen, JM | 1 |
| O'Cain, CF | 1 |
| Ingram, RH | 1 |
| Ahrén, B | 1 |
| Karlsson, S | 1 |
| Scheurink, AJ | 1 |
| Steffens, AB | 1 |
| Nielsen, KK | 1 |
| Andersen, CB | 1 |
| Kromann-Andersen, B | 1 |
| Nordling, J | 1 |
| Martinolle, JP | 1 |
| Garcia-Villar, R | 1 |
| Fioramonti, J | 1 |
| Bueno, L | 1 |
| Farghaly, M | 1 |
| Khoursheed, M | 1 |
| Dashti, H | 1 |
| Thulesius, O | 1 |
| Utkan, T | 1 |
| Sarioğlu, Y | 1 |
| Utkan, NZ | 1 |
| Kurnaz, F | 1 |
| Yildirim, S | 1 |
| Stümpel, F | 1 |
| Kucera, T | 1 |
| Jungermann, K | 1 |
| Belouchi, NE | 1 |
| Savineau, JP | 1 |
| Cook, TA | 1 |
| Brading, AF | 1 |
| Mortensen, NJ | 1 |
| Acosta, JJ | 1 |
| San Román, JI | 1 |
| López, MA | 1 |
| Calvo, JJ | 1 |
| Nightingale, AK | 1 |
| Blackman, DJ | 1 |
| Ellis, GR | 1 |
| Schmitt, M | 1 |
| Morris-Thurgood, JA | 1 |
| Jones, EA | 1 |
| Frenneaux, MP | 1 |
| Karamsetty, MR | 1 |
| Klinger, JR | 1 |
| Hill, NS | 1 |
| Menzies, JR | 1 |
| McKee, R | 1 |
| Corbett, AD | 1 |
| De Man, JG | 1 |
| Moreels, TG | 1 |
| De Winter, BY | 1 |
| Bogers, JJ | 1 |
| Van Marck, EA | 1 |
| Herman, AG | 1 |
| Pelckmans, PA | 1 |
| Graf, E | 1 |
| Himmel, HM | 1 |
| Hála, O | 1 |
| Doerfel, C | 1 |
| Schüler, S | 1 |
| Austen, KF | 1 |
| Orange, RP | 1 |
| Zimmerman, TJ | 1 |
| Sharir, M | 1 |
| Nardin, GF | 1 |
| Fuqua, M | 1 |
| Figueiredo, A | 1 |
| Ribeiro, CA | 1 |
| Gonçalo, M | 1 |
| Almeida, L | 1 |
| Poiares-Baptista, A | 1 |
| Teixeira, F | 1 |
| Poe, RH | 1 |
| Harder, RV | 1 |
| Israel, RH | 1 |
| Kallay, MC | 1 |
| Reichert, RW | 1 |
| Shields, MB | 1 |
| Stewart, WC | 1 |
| Coxon, JE | 1 |
| Dickson, C | 1 |
| Taylor, I | 1 |
| Roland, M | 1 |
| Berstad, A | 1 |
| Liavåg, I | 1 |
| Weinstock, FJ | 1 |
| Drance, SM | 1 |
1 review available for carbachol and Chronic Disease
| Article | Year |
|---|---|
Pharmacological advancements in the treatment of chronic anal fissure.
Topics: Administration, Topical; Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Albuterol; Botulinu | 2005 |
2 trials available for carbachol and Chronic Disease
| Article | Year |
|---|---|
Therapeutic index of pilocarpine, carbachol, and timolol with nasolacrimal occlusion.
Topics: Absorption; Carbachol; Chronic Disease; Cornea; Dose-Response Relationship, Drug; Double-Blind Metho | 1992 |
Acid and pepsin secretion in duodenal ulcer patients in response to graded doses of pentagastrin or pentagastrin and carbacholine before and after proximal gastric vagotomy.
Topics: Adult; Aged; Carbachol; Chronic Disease; Depression, Chemical; Dose-Response Relationship, Drug; Dru | 1974 |
33 other studies available for carbachol and Chronic Disease
| Article | Year |
|---|---|
K(Ca)3.1 channel-blockade attenuates airway pathophysiology in a sheep model of chronic asthma.
Topics: Acetamides; Airway Remodeling; Airway Resistance; Animals; Asthma; Blood Vessels; Bronchoalveolar La | 2013 |
Prophylactic role of oral L-arginine on histological and contractile changes in a rat chronic bladder injury model.
Topics: Administration, Oral; Adrenergic beta-Agonists; Animals; Arginine; Carbachol; Cholinergic Agonists; | 2008 |
The effects of chronic hyperlipidemia on bladder function in myocardial infarction-prone Watanabe heritable hyperlipidemic (WHHLMI) rabbits.
Topics: Animals; Atherosclerosis; Calcitonin Gene-Related Peptide; Carbachol; Cholinergic Agonists; Chronic | 2010 |
Combined effect of chronic hypoxia and in vitro exposure to gas pollutants on airway reactivity.
Topics: Acetylcholine; Acrolein; Air Pollutants; Animals; Calcium; Carbachol; Cholinergic Agonists; Chronic | 2002 |
[Sacral neuromodulation in patients with nonobstructive, chronic urinary retention: relevance of the carbachol test and influence of associated nerve lession].
Topics: Adult; Carbachol; Cholinergic Agonists; Chronic Disease; Electric Stimulation Therapy; Female; Human | 2003 |
Varicose disease affects the P2 receptor-mediated responses of human greater saphenous vein.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Adult; Animals; Arteriosclerosis Obliterans; Carbacho | 2004 |
The effects of acute and chronic lithium treatment on rat submandibular salivation.
Topics: Acute Disease; Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Animals; Carbachol; Cholinergic | 2005 |
Mechanisms underlying the maintenance of muscle hypercontractility in a model of postinfective gut dysfunction.
Topics: Acute Disease; Animals; Carbachol; Cells, Cultured; Cholinergic Agonists; Chronic Disease; Cyclooxyg | 2005 |
The G protein-gated potassium current I(K,ACh) is constitutively active in patients with chronic atrial fibrillation.
Topics: Acetylcholine; Aged; Atrial Appendage; Atrial Fibrillation; Bee Venoms; Carbachol; Chronic Disease; | 2005 |
Receptor activated bladder and spinal ATP release in neurally intact and chronic spinal cord injured rats.
Topics: Adenosine Triphosphate; Animals; Atropine; Blood Pressure; Carbachol; Chronic Disease; Female; Micro | 2007 |
Ultrastructural changes in the sheep pancreas stimulated in vivo by secretin, cholecystokinin, and carbachol.
Topics: Amylases; Animals; Carbachol; Cholecystokinin; Chronic Disease; Enzyme Precursors; Female; Microscop | 1982 |
Experimental induction of chronic bronchitis in dogs: effects on airway obstruction and responsiveness.
Topics: Airway Resistance; Animals; Bronchitis; Carbachol; Chronic Disease; Dinoprost; Dogs; Histamine; Lung | 1982 |
Involvement of nitric oxide in neuroglycopenia-induced insulin and glucagon secretion in the mouse.
Topics: Animals; Arginine; Blood Glucose; Carbachol; Catecholamines; Chronic Disease; Deoxyglucose; Drug Int | 1995 |
Length density and total length of acetylcholinesterase positive nerves related to cystometry and in vitro studies of muscle strips in mini-pig urinary bladder after chronic outflow obstruction and recovery from obstruction.
Topics: Acetylcholinesterase; Animals; Carbachol; Cholinergic Fibers; Chronic Disease; Electric Stimulation; | 1995 |
Altered contractility of circular and longitudinal muscle in TNBS-inflamed guinea pig ileum.
Topics: Adrenergic alpha-Agonists; Animals; Carbachol; Chronic Disease; Enteritis; Epinephrine; Gastrointest | 1997 |
Gallbladder motility in laparoscopic cholecystectomy specimens.
Topics: Acute Disease; Animals; Carbachol; Cholecystectomy, Laparoscopic; Cholecystitis; Chronic Disease; Cu | 1997 |
Effects of chronic unilateral internal pudendal arterial occlusion on reactivity of isolated corpus cavernosum strips from rabbits.
Topics: Adenosine; Animals; Arterial Occlusive Diseases; Arteries; Carbachol; Chronic Disease; Dose-Response | 1999 |
Impaired stimulation of intestinal glucose absorption via hepatoenteral nerves in streptozotocin-diabetic rats.
Topics: Acute Disease; Animals; Autonomic Nervous System; Bucladesine; Carbachol; Chronic Disease; Cyclic AM | 1999 |
Effect of chronic hypoxia on calcium signalling in airway smooth muscle cells.
Topics: Acetylcholine; Animals; Calcium; Calcium Channels; Carbachol; Chronic Disease; Hypoxia; In Vitro Tec | 1999 |
Abnormal contractile properties of rectal smooth muscle in chronic ulcerative colitis.
Topics: Acetylcholinesterase; Carbachol; Cell Count; Chronic Disease; Colitis, Ulcerative; Histocytochemistr | 2000 |
Influence of chronic ethanol consumption on the muscarinic cholinergic control of rat pancreatic acinar cells.
Topics: Alcoholism; Amylases; Animals; Carbachol; Cells, Cultured; Central Nervous System Depressants; Choli | 2000 |
Preservation of venous endothelial function in the forearm venous capacitance bed of patients with chronic heart failure despite arterial endothelial dysfunction.
Topics: Aged; Arteries; Carbachol; Chronic Disease; Endothelium, Vascular; Enzyme Inhibitors; Female; Forear | 2001 |
Phytoestrogens restore nitric oxide-mediated relaxation in isolated pulmonary arteries from chronically hypoxic rats.
Topics: Animals; Carbachol; Cholinergic Agonists; Chronic Disease; Dose-Response Relationship, Drug; Estradi | 2001 |
Differential alterations in tachykinin NK2 receptors in isolated colonic circular smooth muscle in inflammatory bowel disease and idiopathic chronic constipation.
Topics: Adult; Aged; Aged, 80 and over; Carbachol; Cholinergic Agonists; Chronic Disease; Colon; Constipatio | 2001 |
Disturbance of the prejunctional modulation of cholinergic neurotransmission during chronic granulomatous inflammation of the mouse ileum.
Topics: Adrenergic Agonists; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; | 2001 |
Molecular basis of downregulation of G-protein-coupled inward rectifying K(+) current (I(K,ACh) in chronic human atrial fibrillation: decrease in GIRK4 mRNA correlates with reduced I(K,ACh) and muscarinic receptor-mediated shortening of action potentials.
Topics: Acetylcholine; Action Potentials; Aged; Atrial Fibrillation; Carbachol; Cells, Cultured; Chronic Dis | 2001 |
Bronchial asthma: the possible role of the chemical mediators of immediate hypersensitivity in the pathogenesis of subacute chronic disease.
Topics: Acetylcholine; Adrenergic beta-Agonists; Anaphylaxis; Asthma; Autacoids; Blood Coagulation Factors; | 1975 |
Mechanism of action of doxepin in the treatment of chronic urticaria.
Topics: Adult; Aged; Animals; Atropine; Carbachol; Chronic Disease; Dimaprit; Doxepin; Female; Gastric Juice | 1990 |
Chronic persistent cough. Experience in diagnosis and outcome using an anatomic diagnostic protocol.
Topics: Adult; Aged; Asthma; Bronchial Provocation Tests; Bronchitis; Carbachol; Chronic Disease; Clinical P | 1989 |
Intraocular pressure response to replacing pilocarpine with carbachol.
Topics: Aged; Carbachol; Chronic Disease; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; | 1988 |
Changes in colonic motility during the development of chronic large bowel obstruction.
Topics: Animals; Carbachol; Chronic Disease; Colon; Gastrointestinal Motility; In Vitro Techniques; Intestin | 1985 |
Glaucoma detection: a three-step technique.
Topics: Acute Disease; Adult; Age Factors; Aqueous Humor; Carbachol; Carbonic Anhydrase Inhibitors; Cholines | 1973 |
Medical management of glaucoma.
Topics: Acute Disease; Carbachol; Carbonic Anhydrase Inhibitors; Child; Cholinesterase Inhibitors; Chronic D | 1967 |