carbachol has been researched along with Bronchial Hyperreactivity in 77 studies
Carbachol: A slowly hydrolyzed CHOLINERGIC AGONIST that acts at both MUSCARINIC RECEPTORS and NICOTINIC RECEPTORS.
Bronchial Hyperreactivity: Tendency of the smooth muscle of the tracheobronchial tree to contract more intensely in response to a given stimulus than it does in the response seen in normal individuals. This condition is present in virtually all symptomatic patients with asthma. The most prominent manifestation of this smooth muscle contraction is a decrease in airway caliber that can be readily measured in the pulmonary function laboratory.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Ozone, a pollutant known to induce airway hyper-responsiveness (AHR), increases morbidity and mortality in patients with obstructive airway diseases and asthma." | 7.76 | 20-HETE mediates ozone-induced, neutrophil-independent airway hyper-responsiveness in mice. ( Blair, IA; Christmas, P; Cooper, PR; Douaidy, K; Mesaros, AC; Mittelman, MA; Panettieri, RA; Soberman, RJ; Stark, CM; Zhang, J, 2010) |
| "For epidemiological purposes carbachol provocation test--like other unspecific bronchial provocation tests--is inappropriate as a single test to classify individuals as asthmatics." | 7.68 | [Longitudinal study of bronchial hyperreactivity using the carbachol test with school children]. ( Forster, J; Hendel-Kramer, A; Kühr, J; Weis, K, 1993) |
| "Inhalative bronchial provocation tests with pharmacodynamic substances, such as histamine, methacholine or carbachol are performed to confirm or exclude bronchial hyperreactivity." | 7.68 | [Carbachol inhalation provocation test using a reservoir method. 4-step test for the assessment of bronchial hyperreactivity]. ( Klein, G; Wagner-Heck, M; Zinn, CG, 1991) |
| "The effects of a new bradykinin-antagonist, NPC-567 (D-Arg [hydroxyproline3, D-phenylalanine7] bradykinin) were studied on antigen-induced airway hyperresponsiveness and inflammation in allergic sheep (n = 7)." | 7.68 | A bradykinin-antagonist blocks antigen-induced airway hyperresponsiveness and inflammation in sheep. ( Abraham, WM; Sielczak, M; Solèr, M, 1990) |
| "The carbachol aerosol was delivered by jet nebulization." | 5.28 | [Clinical and epidemiological application of carbachol for the testing of bronchial hyperreactivity in school-age]. ( Jung, K; Kühr, J, 1991) |
| "The study was conducted to characterize the action of NaF, which had relaxing property in carbachol precontracted isolated bovine bronchus, on airway responsiveness challenged by acetylcholine receptor agonists in rats and asthmatic humans." | 5.10 | Inhaled sodium fluoride decreases airway responsiveness to acetylcholine analogs in vivo. ( Guénard, H; Rouatbi, S; Tabka, Z; Zhao, W, 2002) |
| " Therefore, we decided to study nonspecific bronchial responsiveness following cumulative doses of inhaled carbachol in 44 children with clinical asthma (CA group), 44 children with chronic cough (CC group), 38 children with wheezy bronchitis in the first 2 years of life (WB group), and 40 controls." | 5.09 | Bronchial challenge with carbachol in 3-6-year-old children: body plethysmography assessments. ( Badier, M; Dubus, JC; Guillot, C, 1999) |
| " Comparing the measured variables (maximal deviation from base-line values of Raw and FEV1) during carbachol provocation in the afternoon under Nebivolol and placebo with the values in the morning before any medication (base-line values), there were also no significant detectable differences indicating an increase of bronchial hyperreactivity under Nebivolol treatment." | 5.09 | [Nebivolol (nebilet) a beta blocker of the third generation--also for patients with obstructive lung diseases?]. ( Giebelhaus, V; Matthys, H; von Fallois, J, 2001) |
| "The aim of this study was to establish a relationship between bronchial hyperreactivity to carbachol and reflex bronchomotor response to the activation of cold receptors in the nose, and also to examine whether any differences exist between asthmatic patients with or without symptoms of rhinitis." | 5.08 | Nasal eupnoeic inhalation of cold, dry air increases airway resistance in asthmatic patients. ( Burnet, H; Fontanari, P; Jammes, Y; Zattara-Hartmann, MC, 1997) |
| " The aim of the study was to determine the carbachol and albuterol responsiveness in treated and untreated asthmatic and allergic children exposed to environmental tobacco smoke assessed by urinary cotinine measurements." | 5.08 | Possible interaction between exposure to environmental tobacco smoke and therapy in children with asthma. ( Badier, M; Bruguerolle, B; Dubus, JC; Guillot, C; Oddoze, C, 1998) |
| " The efficacy of the P20 peptide in vivo on airway hyperresponsiveness (AHR) was determined in an ovalbumin (OVA) sensitization and challenge murine model of allergic airway inflammation." | 3.83 | Heat Shock-Related Protein 20 Peptide Decreases Human Airway Constriction Downstream of β2-Adrenergic Receptor. ( Banathy, A; Boyd, KL; Cheung-Flynn, J; Goleniewska, K; Komalavilas, P; Newcomb, DC; Peebles, RS, 2016) |
| "Ozone, a pollutant known to induce airway hyper-responsiveness (AHR), increases morbidity and mortality in patients with obstructive airway diseases and asthma." | 3.76 | 20-HETE mediates ozone-induced, neutrophil-independent airway hyper-responsiveness in mice. ( Blair, IA; Christmas, P; Cooper, PR; Douaidy, K; Mesaros, AC; Mittelman, MA; Panettieri, RA; Soberman, RJ; Stark, CM; Zhang, J, 2010) |
| "Inhaled adenosine induces bronchoconstriction in asthmatic and allergic subjects but not in nonasthmatics." | 3.69 | Adenosine-induced bronchoconstriction in conscious hyperresponsive and sensitized guinea pigs. ( Broadley, KJ; Thorne, JR, 1994) |
| "Within the framework of unspecific inhalation provocation tests with pharmacological substances for the purpose of diagnosing bronchial hyperreactivity, the cholinergics methacholine and carbachol are often used besides histamine." | 3.69 | [Equivalence of methacholine and carbachol in a nonspecific provocation test (dose-response relationship)]. ( Ferlinz, R; Fischer, B; Schlegel, J, 1995) |
| " In 60 patients with assured bronchial hyperreactivity we performed an inhalative bronchial provocation test using carbachol." | 3.69 | [Change in bronchial hyperreactivity with nCPAP respiration in patients with sleep related respiratory disorders]. ( Dorow, P; Luding, K; Meissner, P; Thalhofer, S, 1997) |
| "Bronchial reactivity to carbachol, estimated by the PD65, the provocation dose of inhaled carbachol inducing a 65% increase of baseline respiratory resistance, was measured in 355 asthmatic children (age 8." | 3.68 | Interfering factors to sensitivity and specificity of bronchial reactivity in children. ( Gschwend-Eigenmann, S; Kraemer, R; Schöni, MH; Sommer, CW; Stadler, BM, 1993) |
| "For epidemiological purposes carbachol provocation test--like other unspecific bronchial provocation tests--is inappropriate as a single test to classify individuals as asthmatics." | 3.68 | [Longitudinal study of bronchial hyperreactivity using the carbachol test with school children]. ( Forster, J; Hendel-Kramer, A; Kühr, J; Weis, K, 1993) |
| "Inhalative bronchial provocation tests with pharmacodynamic substances, such as histamine, methacholine or carbachol are performed to confirm or exclude bronchial hyperreactivity." | 3.68 | [Carbachol inhalation provocation test using a reservoir method. 4-step test for the assessment of bronchial hyperreactivity]. ( Klein, G; Wagner-Heck, M; Zinn, CG, 1991) |
| "The effects of a new bradykinin-antagonist, NPC-567 (D-Arg [hydroxyproline3, D-phenylalanine7] bradykinin) were studied on antigen-induced airway hyperresponsiveness and inflammation in allergic sheep (n = 7)." | 3.68 | A bradykinin-antagonist blocks antigen-induced airway hyperresponsiveness and inflammation in sheep. ( Abraham, WM; Sielczak, M; Solèr, M, 1990) |
| " Bronchial challenges were then performed with increasing concentrations of carbachol, and dose-response curves were constructed." | 2.67 | Different effects of nasal and bronchial glucocorticosteroid administration on bronchial hyperresponsiveness in patients with allergic rhinitis. ( Aubier, M; Clerici, C; Herman, D; Levy, J; Neukirch, F, 1992) |
| "Preterm birth was induced in sheep 12 days before term; controls were born at term ( approximately 147 days)." | 1.35 | Lung function in developing lambs: is it affected by preterm birth? ( De Matteo, R; Harding, R; Koumoundouros, E; Snibson, K; Thompson, B, 2009) |
| "Inflammation was evoked by intranasal administration of Escherichia coli lipopolysaccharide (60 microl, 167 microg/ml) in TRPV1 knockout (TRPV1(-/-)) mice and their wild-type counterparts (TRPV1(+/+)) 24 h before measurement." | 1.34 | Role of transient receptor potential vanilloid 1 receptors in endotoxin-induced airway inflammation in the mouse. ( Börzsei, R; Elekes, K; Helyes, Z; Kereskai, L; Németh, J; Pintér, E; Pozsgai, G; Sándor, K; Szabó, A; Szolcsányi, J, 2007) |
| "Indomethacin pretreatment did not modify the spasmogen responses of the explant." | 1.33 | Organ-cultured airway explants: a new model of airway hyperresponsiveness. ( Brayden, J; Morin, C; Proteau, S; Rousseau, E, 2005) |
| " Dose-response curves for carbachol were examined to determine whether this relationship can be summarized by means of a continuous index likely to be calculable for all subjects, namely the two-point dose response slope (DRS) of mean resistance (Rm) and resistance at 10 Hz (R10) measured by the forced oscillation technique (FOT)." | 1.30 | Dose-response slope of forced oscillation and forced expiratory parameters in bronchial challenge testing. ( Bohadana, AB; Megherbi, SE; Peslin, R; Pham, QT; Sauleau, EA; Teculescu, D; Wild, P, 1999) |
| ") did not bronchodilate but caused a parallel 7 fold rightward shift in the histamine dose-response curve." | 1.29 | Inhibition of bronchospasm and ozone-induced airway hyperresponsiveness in the guinea-pig by CDP840, a novel phosphodiesterase type 4 inhibitor. ( Gozzard, N; Higgs, G; Holbrook, M; Hughes, B; James, T, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 45 (58.44) | 18.2507 |
| 2000's | 29 (37.66) | 29.6817 |
| 2010's | 3 (3.90) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Banathy, A | 1 |
| Cheung-Flynn, J | 1 |
| Goleniewska, K | 1 |
| Boyd, KL | 1 |
| Newcomb, DC | 1 |
| Peebles, RS | 1 |
| Komalavilas, P | 1 |
| Jain, D | 1 |
| Keslacy, S | 1 |
| Tliba, O | 1 |
| Cao, Y | 1 |
| Kierstein, S | 1 |
| Amin, K | 1 |
| Panettieri, RA | 2 |
| Haczku, A | 1 |
| Amrani, Y | 1 |
| Aimbire, F | 1 |
| de Lima, FM | 1 |
| Costa, MS | 1 |
| Albertini, R | 1 |
| Correa, JC | 1 |
| Iversen, VV | 1 |
| Bjordal, JM | 1 |
| Matera, MG | 1 |
| Calzetta, L | 1 |
| Parascandolo, V | 1 |
| Curradi, G | 1 |
| Rogliani, P | 1 |
| Cazzola, M | 1 |
| De Matteo, R | 1 |
| Snibson, K | 1 |
| Thompson, B | 1 |
| Koumoundouros, E | 1 |
| Harding, R | 1 |
| Cooper, PR | 1 |
| Mesaros, AC | 1 |
| Zhang, J | 1 |
| Christmas, P | 1 |
| Stark, CM | 1 |
| Douaidy, K | 1 |
| Mittelman, MA | 1 |
| Soberman, RJ | 1 |
| Blair, IA | 1 |
| Elekes, K | 3 |
| Sandor, K | 3 |
| Moricz, A | 1 |
| Kereskai, L | 3 |
| Kemeny, A | 1 |
| Szoke, E | 1 |
| Perkecz, A | 1 |
| Reglodi, D | 1 |
| Hashimoto, H | 1 |
| Pinter, E | 3 |
| Szolcsanyi, J | 3 |
| Helyes, Z | 3 |
| Zhao, W | 1 |
| Rouatbi, S | 1 |
| Tabka, Z | 1 |
| Guénard, H | 1 |
| Catalli, A | 1 |
| Janssen, LJ | 6 |
| Moerloose, KB | 1 |
| Pauwels, RA | 3 |
| Joos, GF | 2 |
| Satoh, I | 1 |
| Saito, M | 1 |
| Kinoshita, Y | 1 |
| Shomori, K | 1 |
| Suzuki, H | 1 |
| Yamada, M | 1 |
| Kono, T | 1 |
| Satoh, K | 1 |
| Morin, C | 1 |
| Proteau, S | 1 |
| Rousseau, E | 1 |
| Brayden, J | 1 |
| Ferrara, TJ | 1 |
| Mueller, C | 1 |
| Sahu, N | 1 |
| Ben-Jebria, A | 3 |
| August, A | 1 |
| Liu, C | 1 |
| Tazzeo, T | 2 |
| Barrio, J | 1 |
| Cortijo, J | 1 |
| Milara, J | 1 |
| Mata, M | 1 |
| Guijarro, R | 1 |
| Blasco, P | 1 |
| Morcillo, EJ | 1 |
| Kasaian, MT | 1 |
| Donaldson, DD | 1 |
| Tchistiakova, L | 1 |
| Marquette, K | 1 |
| Tan, XY | 1 |
| Ahmed, A | 4 |
| Jacobson, BA | 1 |
| Widom, A | 1 |
| Cook, TA | 1 |
| Xu, X | 1 |
| Barry, AB | 1 |
| Goldman, SJ | 1 |
| Abraham, WM | 6 |
| Card, JW | 1 |
| Voltz, JW | 1 |
| Ferguson, CD | 1 |
| Carey, MA | 1 |
| DeGraff, LM | 1 |
| Peddada, SD | 1 |
| Morgan, DL | 1 |
| Zeldin, DC | 1 |
| Németh, J | 2 |
| Pozsgai, G | 2 |
| Börzsei, R | 1 |
| Szabó, A | 1 |
| Richter, M | 1 |
| Cloutier, S | 1 |
| Sirois, P | 2 |
| Yamakage, M | 1 |
| Iwasaki, S | 1 |
| Satoh, JI | 1 |
| Namiki, A | 1 |
| Tékus, V | 1 |
| Bánvölgyi, A | 1 |
| Szuts, T | 1 |
| Kéri, G | 1 |
| Farghaly, HS | 1 |
| Blagbrough, IS | 1 |
| Medina-Tato, DA | 1 |
| Watson, ML | 1 |
| Chiba, Y | 1 |
| Misawa, M | 1 |
| Bayle, JY | 1 |
| Arnouk, H | 1 |
| de Perthuis, D | 1 |
| Chouvet, B | 1 |
| Germain-Pastene, M | 1 |
| Cozon, G | 1 |
| Béjui-Thivollet, F | 1 |
| Pérol, M | 1 |
| Sanson, C | 1 |
| Guérin, JC | 1 |
| Siekmeier, R | 1 |
| Buhl, R | 1 |
| Schultze-Werninghaus, G | 1 |
| Kronenberger, H | 1 |
| Kraemer, R | 1 |
| Sommer, CW | 1 |
| Gschwend-Eigenmann, S | 1 |
| Schöni, MH | 1 |
| Stadler, BM | 1 |
| Marthan, R | 3 |
| Rossetti, M | 1 |
| Savineau, JP | 3 |
| Ultman, JS | 1 |
| Thorne, JR | 1 |
| Broadley, KJ | 1 |
| Itabashi, S | 1 |
| Ohrui, T | 1 |
| Sekizawa, K | 1 |
| Matsuzaki, Y | 1 |
| Sasaki, H | 1 |
| Claussen, M | 1 |
| Sill, V | 1 |
| Lansing, MW | 1 |
| Cortes, A | 2 |
| Sielczak, MW | 2 |
| Wanner, A | 1 |
| Forster, J | 1 |
| Hendel-Kramer, A | 1 |
| Weis, K | 1 |
| Kühr, J | 2 |
| Clark, JM | 1 |
| Fishman, CE | 1 |
| Forteza, R | 1 |
| Warne, RL | 1 |
| Moore, WR | 1 |
| Tanaka, RD | 1 |
| Anticevich, SZ | 1 |
| Hughes, JM | 1 |
| Black, JL | 1 |
| Armour, CL | 1 |
| Bloemen, PG | 2 |
| Buckley, TL | 2 |
| van den Tweel, MC | 2 |
| Henricks, PA | 2 |
| Redegeld, FA | 2 |
| Koster, AS | 2 |
| Nijkamp, FP | 3 |
| Kips, JC | 2 |
| Brusselle, GJ | 1 |
| Peleman, RA | 1 |
| Tavernier, JH | 1 |
| Devos, RR | 1 |
| Bramley, AM | 1 |
| Langlands, JM | 1 |
| Jones, AK | 1 |
| Burgoyne, DL | 1 |
| Li, Y | 1 |
| Andersen, RJ | 1 |
| Salari, H | 1 |
| Schlegel, J | 1 |
| Fischer, B | 1 |
| Ferlinz, R | 2 |
| Buijs, J | 1 |
| Egbers, MW | 1 |
| Holbrook, M | 1 |
| Gozzard, N | 1 |
| James, T | 1 |
| Higgs, G | 1 |
| Hughes, B | 1 |
| Yamaguchi, H | 1 |
| McCullough, JR | 1 |
| Jia, Y | 1 |
| Xu, L | 1 |
| Turner, DJ | 1 |
| Martin, JG | 2 |
| Florio, C | 1 |
| Styhler, A | 1 |
| Heisler, S | 1 |
| Lamblin, C | 1 |
| Tillie-Leblond, I | 1 |
| Darras, J | 1 |
| Dubrulle, F | 1 |
| Chevalier, D | 1 |
| Cardot, E | 1 |
| Perez, T | 1 |
| Wallaert, B | 1 |
| Piquet, JJ | 1 |
| Tonnel, AB | 1 |
| Källström, BL | 1 |
| Sjöberg, J | 1 |
| Waldeck, B | 1 |
| Song, P | 1 |
| Milanese, M | 1 |
| Crimi, E | 1 |
| Rehder, K | 1 |
| Brusasco, V | 1 |
| Klein, G | 2 |
| Thalhofer, S | 1 |
| Dorow, P | 1 |
| Meissner, P | 1 |
| Luding, K | 1 |
| Fontanari, P | 1 |
| Zattara-Hartmann, MC | 1 |
| Burnet, H | 1 |
| Jammes, Y | 1 |
| McGrogan, I | 2 |
| Wattie, J | 4 |
| O'Byrne, PM | 3 |
| Daniel, EE | 2 |
| Molinari, JF | 1 |
| Campo, C | 2 |
| Shakir, S | 1 |
| Ahmed, T | 2 |
| Dubus, JC | 2 |
| Oddoze, C | 1 |
| Badier, M | 3 |
| Guillot, C | 3 |
| Bruguerolle, B | 1 |
| Leroyer, C | 1 |
| Dewitte, JD | 1 |
| Bassanets, A | 1 |
| Boutoux, M | 1 |
| Daniel, C | 1 |
| Clavier, J | 1 |
| Yagi, Y | 1 |
| Kuwahara, M | 2 |
| Maeda, M | 1 |
| Kadota, H | 2 |
| Saegusa, S | 1 |
| Birumachi, J | 1 |
| Sugano, S | 1 |
| Nishibata, R | 2 |
| Mikami, H | 2 |
| Tsubone, H | 2 |
| Bohadana, AB | 1 |
| Peslin, R | 1 |
| Megherbi, SE | 1 |
| Teculescu, D | 1 |
| Sauleau, EA | 1 |
| Wild, P | 1 |
| Pham, QT | 1 |
| Lin, Kc | 2 |
| Ateeq, HS | 1 |
| Hsiung, SH | 1 |
| Chong, LT | 1 |
| Zimmerman, CN | 1 |
| Castro, A | 1 |
| Lee, WC | 1 |
| Hammond, CE | 1 |
| Kalkunte, S | 1 |
| Chen, LL | 1 |
| Pepinsky, RB | 1 |
| Leone, DR | 2 |
| Sprague, AG | 1 |
| Gill, A | 2 |
| Lobb, RR | 2 |
| Adams, SP | 2 |
| Roux, E | 1 |
| Hyvelin, JM | 1 |
| Djurić, VJ | 1 |
| Otis, J | 1 |
| Pol'ner, SA | 1 |
| Chervinskaia, TA | 1 |
| Ungo, J | 1 |
| Zhou, M | 1 |
| Tournoy, KG | 1 |
| Lauredo, IT | 1 |
| Botinnikova, Y | 1 |
| Pepinsky, B | 1 |
| Delpierre, S | 1 |
| Fornaris, E | 1 |
| Jacquin, M | 1 |
| Carvalho, CR | 1 |
| Jancar, S | 1 |
| Conroy, D | 1 |
| Lu-Chao, H | 1 |
| Matthys, H | 1 |
| Giebelhaus, V | 1 |
| von Fallois, J | 1 |
| Aubier, M | 1 |
| Levy, J | 1 |
| Clerici, C | 1 |
| Neukirch, F | 1 |
| Herman, D | 1 |
| Kulus, M | 1 |
| Milanowski, A | 1 |
| Zawadzka, A | 1 |
| Czarnocka, E | 1 |
| Wagner-Heck, M | 1 |
| Zinn, CG | 1 |
| Jung, K | 1 |
| Solèr, M | 1 |
| Sielczak, M | 1 |
7 trials available for carbachol and Bronchial Hyperreactivity
| Article | Year |
|---|---|
Inhaled sodium fluoride decreases airway responsiveness to acetylcholine analogs in vivo.
Topics: Acetylcholine; Administration, Inhalation; Adult; Airway Resistance; Animals; Asthma; Blood Pressure | 2002 |
[Modification of nonspecific bronchial hyperreactivity to cold air hyperventilation and carbachol by nedocromil and budesonide].
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Asthma; Bronchial Hyperreactivity; Bronchial Provoca | 1993 |
Nasal eupnoeic inhalation of cold, dry air increases airway resistance in asthmatic patients.
Topics: Administration, Inhalation; Adult; Airway Resistance; Analysis of Variance; Asthma; Bronchial Hyperr | 1997 |
Possible interaction between exposure to environmental tobacco smoke and therapy in children with asthma.
Topics: Adolescent; Albuterol; Asthma; Biomarkers; Bronchial Hyperreactivity; Bronchial Provocation Tests; B | 1998 |
Bronchial challenge with carbachol in 3-6-year-old children: body plethysmography assessments.
Topics: Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchitis; Bronchoconstrictor Agent | 1999 |
[Nebivolol (nebilet) a beta blocker of the third generation--also for patients with obstructive lung diseases?].
Topics: Administration, Oral; Adolescent; Adrenergic beta-Antagonists; Adult; Aged; Asthma; Benzopyrans; Bro | 2001 |
Different effects of nasal and bronchial glucocorticosteroid administration on bronchial hyperresponsiveness in patients with allergic rhinitis.
Topics: Administration, Inhalation; Administration, Intranasal; Adult; Aerosols; Airway Resistance; Beclomet | 1992 |
70 other studies available for carbachol and Bronchial Hyperreactivity
| Article | Year |
|---|---|
Heat Shock-Related Protein 20 Peptide Decreases Human Airway Constriction Downstream of β2-Adrenergic Receptor.
Topics: Actins; Adrenergic beta-2 Receptor Antagonists; Allergens; Animals; Bronchial Hyperreactivity; Carba | 2016 |
Essential role of IFNbeta and CD38 in TNFalpha-induced airway smooth muscle hyper-responsiveness.
Topics: ADP-ribosyl Cyclase 1; Animals; Bradykinin; Bronchial Hyperreactivity; Calcium; Carbachol; Cells, Cu | 2008 |
Effect of low level laser therapy on bronchial hyper-responsiveness.
Topics: Animals; Base Sequence; Bronchial Hyperreactivity; Calcium; Carbachol; DNA Primers; Gene Expression; | 2009 |
Relaxant effect of brain natriuretic peptide in nonsensitized and passively sensitized isolated human bronchi.
Topics: Bronchi; Bronchial Hyperreactivity; Carbachol; Histamine; Humans; Immunization, Passive; In Vitro Te | 2009 |
Lung function in developing lambs: is it affected by preterm birth?
Topics: Airway Resistance; Animals; Animals, Newborn; Breath Tests; Bronchial Hyperreactivity; Bronchial Pro | 2009 |
20-HETE mediates ozone-induced, neutrophil-independent airway hyper-responsiveness in mice.
Topics: Animals; Bronchial Hyperreactivity; Carbachol; Hydroxyeicosatetraenoic Acids; Lipid Peroxidation; Ma | 2010 |
Pituitary adenylate cyclase-activating polypeptide plays an anti-inflammatory role in endotoxin-induced airway inflammation: in vivo study with gene-deleted mice.
Topics: Animals; Bronchi; Bronchial Hyperreactivity; Carbachol; Cholinergic Agonists; Enzyme-Linked Immunoso | 2011 |
Augmentation of bovine airway smooth muscle responsiveness to carbachol, KCl, and histamine by the isoprostane 8-iso-PGE2.
Topics: Animals; Bronchial Hyperreactivity; Bronchoconstrictor Agents; Carbachol; Cattle; Cholinergic Agonis | 2004 |
Short-term cigarette smoke exposure enhances allergic airway inflammation in mice.
Topics: Animals; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Carbachol; Chemokines; Cytokines; | 2005 |
Effects of cyclohexenonic long-chain fatty alcohol on diabetic rat trachea.
Topics: Animals; Blood Glucose; Body Weight; Bronchial Hyperreactivity; Carbachol; Diabetes Mellitus, Experi | 2005 |
Organ-cultured airway explants: a new model of airway hyperresponsiveness.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Apoptosis; Biomechanica | 2005 |
Reduced airway hyperresponsiveness and tracheal responses during allergic asthma in mice lacking tyrosine kinase inducible T-cell kinase.
Topics: Acetylcholine; Adoptive Transfer; Animals; Asthma; Bronchial Hyperreactivity; Carbachol; CD4-Positiv | 2006 |
Isoprostane-induced airway hyperresponsiveness is dependent on internal Ca2+ handling and Rho/ROCK signaling.
Topics: Amides; Animals; Bronchial Hyperreactivity; Calcium; Carbachol; Cattle; Dinoprostone; Enzyme Inhibit | 2006 |
In vitro tracheal hyperresponsiveness to muscarinic receptor stimulation by carbachol in a rat model of bleomycin-induced pulmonary fibrosis.
Topics: Animals; Bleomycin; Bronchial Hyperreactivity; Calcium Signaling; Carbachol; Disease Models, Animal; | 2006 |
Efficacy of IL-13 neutralization in a sheep model of experimental asthma.
Topics: Amino Acid Sequence; Animals; Antibodies; Ascaris suum; Asthma; Base Sequence; Bronchial Hyperreacti | 2007 |
Male sex hormones promote vagally mediated reflex airway responsiveness to cholinergic stimulation.
Topics: Animals; Bronchi; Bronchial Hyperreactivity; Carbachol; Dihydrotestosterone; Female; In Vitro Techni | 2007 |
Role of transient receptor potential vanilloid 1 receptors in endotoxin-induced airway inflammation in the mouse.
Topics: Animals; Bronchial Hyperreactivity; Carbachol; Endotoxins; Inflammation; Lipopolysaccharides; Mice; | 2007 |
Endothelin, PAF and thromboxane A2 in allergic pulmonary hyperreactivity in mice.
Topics: Animals; Antihypertensive Agents; Bronchial Hyperreactivity; Carbachol; Endothelin B Receptor Antago | 2007 |
Inhibitory effects of the alpha-2 adrenergic agonists clonidine and dexmedetomidine on enhanced airway tone in ovalbumin-sensitized guinea pigs.
Topics: Acetylcholine; Adrenergic alpha-Agonists; Airway Obstruction; Animals; Bronchial Hyperreactivity; Ca | 2008 |
Inhibitory effects of synthetic somatostatin receptor subtype 4 agonists on acute and chronic airway inflammation and hyperreactivity in the mouse.
Topics: Animals; Anti-Inflammatory Agents; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; B | 2008 |
Interleukin 13 increases contractility of murine tracheal smooth muscle by a phosphoinositide 3-kinase p110delta-dependent mechanism.
Topics: Adenine; Animals; Bronchial Hyperreactivity; Carbachol; Chromones; Class I Phosphatidylinositol 3-Ki | 2008 |
Inhibition of neutral endopeptidase increases airway responsiveness to ACh in nonsensitized normal rats.
Topics: Acetylcholine; Administration, Inhalation; Animals; Bronchial Hyperreactivity; Capillary Permeabilit | 1995 |
[Indolent mastocytosis and bronchial hyperreactivity. A case report].
Topics: Adult; Bronchial Hyperreactivity; Carbachol; Female; Forced Expiratory Volume; Humans; Immunoglobuli | 1994 |
Unspecific bronchial reactivity to carbachol in healthy subjects--effect of age and smoking habits.
Topics: Adult; Age Factors; Airway Resistance; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronc | 1994 |
Interfering factors to sensitivity and specificity of bronchial reactivity in children.
Topics: Adolescent; Asthma; Bronchi; Bronchial Hyperreactivity; Bronchial Provocation Tests; Carbachol; Chil | 1993 |
Human bronchial smooth muscle responsiveness after in vitro exposure to acrolein.
Topics: Acrolein; Bronchi; Bronchial Hyperreactivity; Bronchoconstriction; Carbachol; Histamine; Humans; In | 1994 |
Adenosine-induced bronchoconstriction in conscious hyperresponsive and sensitized guinea pigs.
Topics: Adenosine; Animals; Asthma; Bronchial Hyperreactivity; Bronchoconstriction; Carbachol; Guinea Pigs; | 1994 |
Peripheral airway hyperresponsiveness in the choline-deficiently fed rat.
Topics: Acetylcholine; Acetylcholinesterase; Animals; Bronchial Hyperreactivity; Carbachol; Choline Deficien | 1993 |
Oxygen radicals contribute to antigen-induced airway hyperresponsiveness in conscious sheep.
Topics: Aerosols; Analysis of Variance; Animals; Antigens, Helminth; Ascaris suum; Bronchial Hyperreactivity | 1993 |
[Longitudinal study of bronchial hyperreactivity using the carbachol test with school children].
Topics: Adolescent; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Carbachol; Child; Cohort | 1993 |
Tryptase inhibitors block allergen-induced airway and inflammatory responses in allergic sheep.
Topics: Airway Resistance; Allergens; Animals; Antigens, Helminth; Ascaris suum; Asthma; Benzimidazoles; Bro | 1995 |
Induction of human airway hyperresponsiveness by tumour necrosis factor-alpha.
Topics: Acetylcholine; Aged; Allergens; Bronchi; Bronchial Hyperreactivity; Carbachol; Electric Stimulation; | 1995 |
LFA-1, and not Mac-1, is crucial for the development of hyperreactivity in a murine model of nonallergic asthma.
Topics: Animals; Antibodies, Monoclonal; Asthma; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Ca | 1996 |
Interleukin-12 inhibits antigen-induced airway hyperresponsiveness in mice.
Topics: Animals; Antigens; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Carbachol; Immunization; | 1996 |
Effects of IZP-94005 (contignasterol) on antigen-induced bronchial responsiveness in ovalbumin-sensitized guinea-pigs.
Topics: Administration, Inhalation; Airway Resistance; Analysis of Variance; Animals; Anti-Asthmatic Agents; | 1995 |
[Equivalence of methacholine and carbachol in a nonspecific provocation test (dose-response relationship)].
Topics: Adolescent; Adult; Airway Resistance; Bronchial Hyperreactivity; Bronchial Provocation Tests; Carbac | 1995 |
Toxocara canis-induced airway eosinophilia and tracheal hyporeactivity in guinea pigs and mice.
Topics: Animals; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Carbachol; Dinoprostone; Dose-Resp | 1995 |
Inhibition of bronchospasm and ozone-induced airway hyperresponsiveness in the guinea-pig by CDP840, a novel phosphodiesterase type 4 inhibitor.
Topics: Analysis of Variance; Animals; Benzamides; Bronchial Hyperreactivity; Bronchoconstriction; Carbachol | 1996 |
S-albuterol exacerbates calcium responses to carbachol in airway smooth muscle cells.
Topics: Albuterol; Animals; Bronchial Hyperreactivity; Calcium; Carbachol; Cattle; Cells, Cultured; Muscle, | 1996 |
LFA-1 and ICAM-1 are crucial for the induction of hyperreactivity in the mouse airways.
Topics: Animals; Antibodies, Monoclonal; Asthma; Bronchial Hyperreactivity; Carbachol; Disease Models, Anima | 1996 |
Endogenous nitric oxide contributes to strain-related differences in airway responsiveness in rats.
Topics: Animals; Bronchial Hyperreactivity; Carbachol; Cyclic AMP; Cyclic GMP; Enzyme Inhibitors; Epithelium | 1996 |
Mechanical responses of tracheal tissue in vitro: dependence on the tissue preparation employed and relationship to smooth muscle content.
Topics: Animals; Biomechanical Phenomena; Bronchial Hyperreactivity; Carbachol; Guinea Pigs; In Vitro Techni | 1996 |
Sequential evaluation of pulmonary function and bronchial hyperresponsiveness in patients with nasal polyposis: a prospective study.
Topics: Adolescent; Adult; Aged; Beclomethasone; Bronchial Hyperreactivity; Bronchial Provocation Tests; Car | 1997 |
Steric aspects of formoterol and terbutaline: is there an adverse effect of the distomer on airway smooth muscle function?
Topics: Adrenergic beta-Agonists; Animals; Bronchi; Bronchial Hyperreactivity; Carbachol; Choline; Electric | 1996 |
Allergen challenge of passively sensitized human bronchi alters M2 and beta2 receptor function.
Topics: Adrenergic beta-Agonists; Adult; Aged; Albuterol; Allergens; Animals; Asthma; Bronchi; Bronchial Hyp | 1997 |
[Recommendations for implementing bronchial provocation tests with pharmacologic substances. German Society of Pneumology--Scientific "Bronchial Provocation Tests" Study Group].
Topics: Acetylcholine; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoconstrictor Agents; Ca | 1997 |
[Change in bronchial hyperreactivity with nCPAP respiration in patients with sleep related respiratory disorders].
Topics: Adult; Aged; Airway Resistance; Bronchi; Bronchial Hyperreactivity; Bronchial Provocation Tests; Car | 1997 |
[Pharmacologic substances for bronchial provocation testing].
Topics: Acetylcholine; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoconstrictor Agents; Ca | 1997 |
Myogenic and neurogenic mechanisms and arachidonate metabolites in bronchial muscle response to allergen.
Topics: Allergens; Animals; Arachidonic Acids; Ascaris suum; Bronchi; Bronchial Hyperreactivity; Carbachol; | 1997 |
Release of epithelium-derived PGE2 from canine trachea after antigen inhalation.
Topics: Administration, Inhalation; Allergens; Animals; Antigens, Helminth; Ascaris suum; Asthma; Bronchial | 1998 |
Inhibition of antigen-induced airway hyperresponsiveness by ultralow molecular-weight heparin.
Topics: Administration, Inhalation; Aerosols; Airway Resistance; Animals; Anticoagulants; Antigens, Helminth | 1998 |
Occupational asthma due to chromium.
Topics: Adult; Asthma; Bronchial Hyperreactivity; Carbachol; Chromium; Construction Materials; Forced Expira | 1998 |
Airway responsiveness to acetylcholine in congenitally bronchial-hypersensitive (BHS) and bronchial-hyposensitive (BHR) guinea pigs in vivo and in vitro.
Topics: Acetylcholine; Acetylcholinesterase; Animals; Bronchial Hyperreactivity; Bronchial Provocation Tests | 1998 |
Dose-response slope of forced oscillation and forced expiratory parameters in bronchial challenge testing.
Topics: Adult; Airway Resistance; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoconstrictor | 1999 |
Selective, tight-binding inhibitors of integrin alpha4beta1 that inhibit allergic airway responses.
Topics: Animals; Anti-Allergic Agents; Binding Sites; Bronchial Hyperreactivity; Carbachol; Cell Adhesion; C | 1999 |
Human isolated airway contraction: interaction between air pollutants and passive sensitization.
Topics: Acrolein; Adult; Air Pollutants; Airway Resistance; Asthma; Bronchi; Bronchial Hyperreactivity; Bron | 1999 |
In vitro airway responsiveness of Flinders sensitive and resistant line rats.
Topics: Airway Resistance; Allergens; Animals; Bronchi; Bronchial Hyperreactivity; Bronchoconstriction; Bron | 2000 |
[Bronchial reactivity as factor of effectiveness of new antiasthmatic drugs].
Topics: Administration, Inhalation; Airway Resistance; Anti-Asthmatic Agents; Asthma; Beclomethasone; Bronch | 2000 |
Inhibition of allergic late airway responses by inhaled heparin-derived oligosaccharides.
Topics: Administration, Inhalation; Airway Resistance; Animals; Antigens; Bronchial Hyperreactivity; Broncho | 2000 |
Endogenous interleukin-10 suppresses allergen-induced airway inflammation and nonspecific airway responsiveness.
Topics: Allergens; Animals; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoalveolar | 2000 |
A small-molecule, tight-binding inhibitor of the integrin alpha(4)beta(1) blocks antigen-induced airway responses and inflammation in experimental asthma in sheep.
Topics: Animals; Asthma; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Carbachol; Eosinophils; In | 2000 |
Value of bronchial challenge in scuba diving candidates.
Topics: Adult; Airway Resistance; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Carbachol; | 2000 |
Antigen-induced bronchial hyperreactivity and bronchopulmonary inflammation in rats: effect of TNF receptor binding protein.
Topics: Animals; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Bronchopneumonia; Carbachol; Carri | 2001 |
Effect of M2 and M3 muscarinic receptors on airway responsiveness to carbachol in bronchial-hypersensitive (BHS) and bronchial-hyposensitive (BHR) guinea pigs.
Topics: Animals; Bronchial Hyperreactivity; Carbachol; Diamines; Gene Expression; Guinea Pigs; Lung; Male; M | 2001 |
Muscarinic excitation-contraction coupling mechanisms in tracheal and bronchial smooth muscles.
Topics: Animals; Bronchi; Bronchial Hyperreactivity; Calcium; Calcium-Transporting ATPases; Carbachol; Chlor | 2001 |
Effect of in vitro nitrogen dioxide exposure on human bronchial smooth muscle response.
Topics: Acetylcholine; Airway Resistance; Bronchial Hyperreactivity; Bronchial Provocation Tests; Carbachol; | 1992 |
[Reactivity of the bronchi as a function of their initial state in children with asthma].
Topics: Administration, Inhalation; Adolescent; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tes | 1991 |
[Carbachol inhalation provocation test using a reservoir method. 4-step test for the assessment of bronchial hyperreactivity].
Topics: Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Carbachol; Dose-Response Relationshi | 1991 |
[Clinical and epidemiological application of carbachol for the testing of bronchial hyperreactivity in school-age].
Topics: Bronchial Hyperreactivity; Bronchial Provocation Tests; Carbachol; Child; Dose-Response Relationship | 1991 |
A bradykinin-antagonist blocks antigen-induced airway hyperresponsiveness and inflammation in sheep.
Topics: Administration, Inhalation; Animals; Antigens; Bradykinin; Bronchial Hyperreactivity; Bronchoalveola | 1990 |