carbachol has been researched along with Breast Cancer in 8 studies
Carbachol: A slowly hydrolyzed CHOLINERGIC AGONIST that acts at both MUSCARINIC RECEPTORS and NICOTINIC RECEPTORS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We have previously reported that breast tumors highly express functional muscarinic acetylcholine receptors (mAChRs) that regulate tumor progression." | 5.42 | Participation of non-neuronal muscarinic receptors in the effect of carbachol with paclitaxel on human breast adenocarcinoma cells. Roles of nitric oxide synthase and arginase. ( Español, AJ; Rojo, D; Salem, A; Sales, ME, 2015) |
| " We studied the action of a combination of low doses of the muscarinic agonist carbachol plus paclitaxel, a chemotherapeutic agent frequently used in breast cancer treatment, in terms of effectiveness." | 3.79 | Muscarinic activation enhances the anti-proliferative effect of paclitaxel in murine breast tumor cells. ( Dmytrenko, G; Español, AJ; Jacob, G; Sales, ME, 2013) |
| "Carbachol (Cch), a muscarinic acetylcholine receptor (mAChR) agonist, increases intracellular-free Ca(2+) mobilization and induces mitogen-activated protein kinase/extracellular signal-regulated kinase (MAPK/ERK) phosphorylation in MCF-7 human breast cancer cells." | 3.73 | Activation of MAP kinase by muscarinic cholinergic receptors induces cell proliferation and protein synthesis in human breast cancer cells. ( Jiménez, E; Montiel, M, 2005) |
| "We have previously reported that breast tumors highly express functional muscarinic acetylcholine receptors (mAChRs) that regulate tumor progression." | 1.42 | Participation of non-neuronal muscarinic receptors in the effect of carbachol with paclitaxel on human breast adenocarcinoma cells. Roles of nitric oxide synthase and arginase. ( Español, AJ; Rojo, D; Salem, A; Sales, ME, 2015) |
| "Immunoglobulin G (IgG) from breast cancer patients in T1N0Mx stage (tumor size≤2 cm, without lymph node metastasis) mimics the action of the muscarinic agonist carbachol stimulating MCF-7 cell proliferation, migration and invasion." | 1.39 | Autoantibodies against muscarinic receptors in breast cancer: their role in tumor angiogenesis. ( Azar, ME; Castro, ME; Fiszman, GL; Lombardi, MG; Morgado, CC; Negroni, MP; Pelegrina, LT; Sales, ME, 2013) |
| "IgG from breast cancer patients in stage I could be promoting tumor progression by regulating migration and MMP-9 activity in tumor cells via mAChR activation." | 1.39 | Immunoglobulin g from breast cancer patients regulates MCF-7 cells migration and MMP-9 activity by stimulating muscarinic acetylcholine receptors. ( Azar, ME; Fiszman, GL; Lombardi, MG; Morgado, CC; Pelegrina, LT; Sales, ME, 2013) |
| "IgG from patients with breast cancer in early stages could be promoting tumor progression by muscarinic activation, and its presence could be determining the prognosis of this illness." | 1.36 | Immunoglobulin G from breast cancer patients in stage I stimulates muscarinic acetylcholine receptors in MCF7 cells and induces proliferation. Participation of nitric oxide synthase-derived nitric oxide. ( Azar, ME; de la Torre, E; Español, AJ; Fiszman, GL; Morgado, CC; Negroni, MP; Pelegrina, LT; Sales, ME, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (25.00) | 29.6817 |
| 2010's | 6 (75.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lombardi, MG | 2 |
| Negroni, MP | 2 |
| Pelegrina, LT | 3 |
| Castro, ME | 1 |
| Fiszman, GL | 4 |
| Azar, ME | 3 |
| Morgado, CC | 3 |
| Sales, ME | 7 |
| Español, AJ | 4 |
| Salem, A | 1 |
| Rojo, D | 1 |
| de la Torre, E | 2 |
| Jacob, G | 1 |
| Dmytrenko, G | 1 |
| Jiménez, E | 1 |
| Montiel, M | 1 |
| Middonno, MC | 1 |
| Farina, M | 1 |
1 review available for carbachol and Breast Cancer
| Article | Year |
|---|---|
Muscarinic Receptors as Targets for Metronomic Therapy in Breast Cancer.
Topics: Administration, Metronomic; Animals; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasm | 2016 |
7 other studies available for carbachol and Breast Cancer
| Article | Year |
|---|---|
Autoantibodies against muscarinic receptors in breast cancer: their role in tumor angiogenesis.
Topics: Animals; Antibodies, Neoplasm; Autoantibodies; Breast Neoplasms; Carbachol; Female; Fibroadenoma; Hu | 2013 |
Participation of non-neuronal muscarinic receptors in the effect of carbachol with paclitaxel on human breast adenocarcinoma cells. Roles of nitric oxide synthase and arginase.
Topics: Adenocarcinoma; Arginase; Breast Neoplasms; Carbachol; Cell Line, Tumor; Drug Therapy, Combination; | 2015 |
Immunoglobulin G from breast cancer patients in stage I stimulates muscarinic acetylcholine receptors in MCF7 cells and induces proliferation. Participation of nitric oxide synthase-derived nitric oxide.
Topics: Autoantibodies; Breast Neoplasms; Carbachol; Carcinoma; Cell Line, Tumor; Cell Proliferation; Cholin | 2010 |
Immunoglobulin g from breast cancer patients regulates MCF-7 cells migration and MMP-9 activity by stimulating muscarinic acetylcholine receptors.
Topics: Autoantibodies; Breast Neoplasms; Carbachol; Cell Movement; Cholinergic Agonists; Enzyme Activation; | 2013 |
Muscarinic activation enhances the anti-proliferative effect of paclitaxel in murine breast tumor cells.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Carbachol; Cell Line, | 2013 |
Activation of MAP kinase by muscarinic cholinergic receptors induces cell proliferation and protein synthesis in human breast cancer cells.
Topics: Biological Transport; Breast Neoplasms; Calcium; Carbachol; Cell Line, Tumor; Cell Proliferation; Ch | 2005 |
Activation of muscarinic cholinergic receptors induces MCF-7 cells proliferation and angiogenesis by stimulating nitric oxide synthase activity.
Topics: Breast Neoplasms; Carbachol; Cell Line, Tumor; Cell Proliferation; Humans; Neovascularization, Patho | 2007 |