carbachol has been researched along with Bladder, Overactive in 44 studies
Carbachol: A slowly hydrolyzed CHOLINERGIC AGONIST that acts at both MUSCARINIC RECEPTORS and NICOTINIC RECEPTORS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Mirabegron is used for treatment of storage symptoms in overactive bladder (OAB) caused by spontaneous bladder smooth muscle contractions." | 8.12 | Inhibition of Full Smooth Muscle Contraction in Isolated Human Detrusor Tissues by Mirabegron Is Limited to Off-Target Inhibition of Neurogenic Contractions. ( Hennenberg, M; Huang, R; Stief, CG; Strittmatter, F; Tamalunas, A; Waidelich, R, 2022) |
| "The aim of this study was to compare the effect of antimuscarinic antagonists on carbachol-induced contraction of normal human bladder and detrusor overactivity associated with benign prostatic hyperplasia (DO/BPH)." | 7.81 | The role of muscarinic receptor subtypes on carbachol-induced contraction of normal human detrusor and overactive detrusor associated with benign prostatic hyperplasia. ( Fuse, M; Kaga, K; Kamai, T; Shibata, C; Uchiyama, T; Yamanishi, T, 2015) |
| "Ascorbic acid and citric acid augmented bladder muscle contraction possibly by enhanced Ca(2+) influx." | 7.75 | Modification of rat detrusor muscle contraction by ascorbic acid and citric acid involving enhanced neurotransmitter release and Ca2+ influx. ( Dasgupta, J; Elliott, RA; Tincello, DG, 2009) |
| "To investigate the effects of menthol, an activator of the temperature-sensitive transient receptor potential family member TRPM8, on detrusor smooth-muscle contraction and the micturition reflex in rats." | 7.74 | Effect of menthol on detrusor smooth-muscle contraction and the micturition reflex in rats. ( Harada, K; Ikeda, S; Kamikawa, Y; Kawahira, K; Nomoto, Y; Ohwatashi, A; Yoshida, A, 2008) |
| "Mirabegron is used for treatment of storage symptoms in overactive bladder (OAB) caused by spontaneous bladder smooth muscle contractions." | 4.12 | Inhibition of Full Smooth Muscle Contraction in Isolated Human Detrusor Tissues by Mirabegron Is Limited to Off-Target Inhibition of Neurogenic Contractions. ( Hennenberg, M; Huang, R; Stief, CG; Strittmatter, F; Tamalunas, A; Waidelich, R, 2022) |
| "To evaluate the effects of the beta-3 adrenoceptor agonist, mirabegron in a mouse model of detrusor overactivity induced by obesity." | 3.85 | Long-term treatment with the beta-3 adrenoceptor agonist, mirabegron ameliorates detrusor overactivity and restores cyclic adenosine monophosphate (cAMP) levels in obese mice. ( Alexandre, EC; Antunes, E; Calmasini, FB; Candido, TZ; da Silva, CPV; da Silva, FH; de Oliveira, MG; Mónica, FZ, 2017) |
| "The aim of this study was to compare the effect of antimuscarinic antagonists on carbachol-induced contraction of normal human bladder and detrusor overactivity associated with benign prostatic hyperplasia (DO/BPH)." | 3.81 | The role of muscarinic receptor subtypes on carbachol-induced contraction of normal human detrusor and overactive detrusor associated with benign prostatic hyperplasia. ( Fuse, M; Kaga, K; Kamai, T; Shibata, C; Uchiyama, T; Yamanishi, T, 2015) |
| " Metformin treatment improved the insulin sensitivity, and normalized the in vitro bladder hypercontractility and cystometric dysfunction in obese mice." | 3.78 | Role of PKC and CaV1.2 in detrusor overactivity in a model of obesity associated with insulin resistance in mice. ( Anhê, GF; Antunes, E; Calixto, MC; De Nucci, G; Grant, AD; Leiria, LO; Lintomen, L; Mónica, FZ; Sollon, C; Zanesco, A, 2012) |
| "Ascorbic acid and citric acid augmented bladder muscle contraction possibly by enhanced Ca(2+) influx." | 3.75 | Modification of rat detrusor muscle contraction by ascorbic acid and citric acid involving enhanced neurotransmitter release and Ca2+ influx. ( Dasgupta, J; Elliott, RA; Tincello, DG, 2009) |
| "To investigate the effects of menthol, an activator of the temperature-sensitive transient receptor potential family member TRPM8, on detrusor smooth-muscle contraction and the micturition reflex in rats." | 3.74 | Effect of menthol on detrusor smooth-muscle contraction and the micturition reflex in rats. ( Harada, K; Ikeda, S; Kamikawa, Y; Kawahira, K; Nomoto, Y; Ohwatashi, A; Yoshida, A, 2008) |
| " Furthermore, the effects of eviprostat on carbachol-induced muscle contraction were evaluated by an in vitro experiment." | 3.74 | Effect of eviprostat on bladder overactivity in an experimental cystitis rat model. ( Fujimoto, N; Kobayashi, M; Matsumoto, S; Matsumoto, T; Nishii, H; Nomura, M, 2008) |
| "Model rats underwent bladder outlet obstruction surgery." | 1.91 | Excitatory purinergic and cholinergic expression changed in a partial bladder outlet obstruction-induced overactive bladder rat model. ( Cao, H; Huang, J; Li, H; Liu, J; Long, Y; Zhang, Y, 2023) |
| "Mice treated with mirabegron or solifenacin displayed significantly fewer voiding events compared to the stressed mice, and voiding frequency in drug-treated animals was comparable to unstressed controls." | 1.72 | Mirabegron and solifenacin are effective for the management of the increased urinary frequency induced by psychological stress in female mice. ( Chess-Williams, R; McDermott, C; Sellers, DJ; West, EG, 2022) |
| "These symptoms are similar to the overactive bladder syndrome." | 1.40 | Izalpinin from fruits of Alpinia oxyphylla with antagonistic activity against the rat bladder contractility. ( Chen, F; Chen, WY; Huang, GJ; Li, H; Li, YH; Tan, YF; Xu, P; Yuan, Y; Zhang, JQ, 2014) |
| "To evaluate chronic hyperlipidemia on bladder function, we examined the functional and histological changes of the bladder in myocardial infarction-prone Watanabe Heritable Hyperlipidemic (WHHLMI) rabbits." | 1.36 | The effects of chronic hyperlipidemia on bladder function in myocardial infarction-prone Watanabe heritable hyperlipidemic (WHHLMI) rabbits. ( Masunaga, K; Nagata, T; Satoji, Y; Shiomi, M; Yoshida, M, 2010) |
| "Organ hypertrophy is often found to be associated with changes in the expression of caveolins and altered density of caveolae in the membrane." | 1.36 | Biochemical and functional correlates of an increased membrane density of caveolae in hypertrophic rat urinary bladder. ( Ekman, M; Shakirova, Y; Swärd, K; Uvelius, B, 2010) |
| "L-carnitine treatment restored the hyporesponsiveness of isoprenaline and the hyperresponsiveness of adenosine-elicited relaxation." | 1.35 | L-carnitine treatment partially restores urinary bladder function of streptozotocin diabetic rats. ( Gur, S; Irat, AM, 2008) |
| "Overactive bladder is a complex and widely prevalent condition, but little is known about its physiopathology." | 1.35 | Long-term nitric oxide deficiency causes muscarinic supersensitivity and reduces beta(3)-adrenoceptor-mediated relaxation, causing rat detrusor overactivity. ( Abdalla, FM; Antunes, E; Báu, FR; Bricola, AA; De Nucci, G; Freitas, LL; Mónica, FZ; Muscará, MN; Porto, CS; Teixeira, SA; Zanesco, A, 2008) |
| "Partial bladder outlet obstruction (PBOO) is believed to change the functions of the detrusor, and can lead to an overactive detrusor (OD)." | 1.33 | Effect of partial bladder outlet obstruction on detrusor compliance, excitability and contractility in rats. ( Hao, P; Li, L; Qiu, G; Song, B, 2006) |
| " Validation showed that carbachol produced a dose-response curve closely mirroring that observed in the isolated muscle strips and demonstrated the dual nature of electrically evoked neurotransmission, consisting of a cholinergic component largely mediated by M(3) receptors and a purinergic component mediated by P2X receptors." | 1.33 | The use of the isolated mouse whole bladder for investigating bladder overactivity. ( Brading, AF; Fabiyi, AC, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 15 (34.09) | 29.6817 |
| 2010's | 24 (54.55) | 24.3611 |
| 2020's | 5 (11.36) | 2.80 |
| Authors | Studies |
|---|---|
| Huang, R | 1 |
| Tamalunas, A | 1 |
| Waidelich, R | 1 |
| Strittmatter, F | 1 |
| Stief, CG | 1 |
| Hennenberg, M | 1 |
| West, EG | 2 |
| McDermott, C | 2 |
| Chess-Williams, R | 3 |
| Sellers, DJ | 2 |
| Huang, J | 1 |
| Li, H | 2 |
| Zhang, Y | 1 |
| Liu, J | 1 |
| Cao, H | 1 |
| Long, Y | 1 |
| Mizutani, H | 1 |
| Sakakibara, F | 1 |
| Sasaki, E | 1 |
| Klee, NS | 1 |
| Moreland, RS | 1 |
| Kendig, DM | 1 |
| Babaoglu, M | 1 |
| Zumrutbas, AE | 1 |
| Acar, IC | 1 |
| Hatip, FB | 1 |
| Kucukatay, V | 1 |
| Eskicorapci, S | 1 |
| Aybek, Z | 1 |
| Michel, MC | 2 |
| La Fuente, JM | 1 |
| Fernández, A | 1 |
| Cuevas, P | 1 |
| González-Corrochano, R | 1 |
| Chen, MX | 1 |
| Angulo, J | 1 |
| Yuan, Y | 1 |
| Tan, YF | 1 |
| Xu, P | 1 |
| Li, YH | 1 |
| Chen, WY | 1 |
| Zhang, JQ | 1 |
| Chen, F | 1 |
| Huang, GJ | 1 |
| Yamanishi, T | 1 |
| Kaga, K | 1 |
| Fuse, M | 1 |
| Shibata, C | 1 |
| Kamai, T | 1 |
| Uchiyama, T | 1 |
| Xin, W | 1 |
| Li, N | 1 |
| Fernandes, VS | 1 |
| Chen, B | 1 |
| Rovner, ES | 2 |
| Petkov, GV | 2 |
| Zhai, K | 1 |
| Yang, Z | 1 |
| Zhu, X | 1 |
| Nyirimigabo, E | 1 |
| Mi, Y | 1 |
| Wang, Y | 1 |
| Liu, Q | 1 |
| Man, L | 1 |
| Wu, S | 1 |
| Jin, J | 1 |
| Ji, G | 1 |
| Zhou, X | 1 |
| Lam, WP | 1 |
| Tang, HC | 1 |
| Koon, CM | 1 |
| Cheng, L | 1 |
| Lau, CB | 1 |
| Liang, W | 1 |
| Leung, PC | 1 |
| Calmasini, FB | 1 |
| de Oliveira, MG | 1 |
| Alexandre, EC | 1 |
| da Silva, FH | 1 |
| da Silva, CPV | 1 |
| Candido, TZ | 1 |
| Antunes, E | 3 |
| Mónica, FZ | 3 |
| Gevaert, T | 1 |
| Owsianik, G | 1 |
| Hutchings, G | 1 |
| Van Leuven, L | 1 |
| Everaerts, W | 1 |
| Nilius, B | 1 |
| De Ridder, D | 1 |
| Gur, S | 1 |
| Irat, AM | 1 |
| Dasgupta, J | 1 |
| Elliott, RA | 1 |
| Tincello, DG | 1 |
| Sand, C | 1 |
| Yoshida, M | 1 |
| Masunaga, K | 1 |
| Nagata, T | 1 |
| Satoji, Y | 1 |
| Shiomi, M | 1 |
| Kita, M | 2 |
| Yunoki, T | 2 |
| Takimoto, K | 1 |
| Miyazato, M | 1 |
| Kita, K | 1 |
| de Groat, WC | 2 |
| Kakizaki, H | 1 |
| Yoshimura, N | 2 |
| Sinha, S | 1 |
| Gupta, S | 1 |
| Malhotra, S | 1 |
| Krishna, NS | 1 |
| Meru, AV | 1 |
| Babu, V | 1 |
| Bansal, V | 1 |
| Garg, M | 1 |
| Kumar, N | 1 |
| Chugh, A | 1 |
| Ray, A | 1 |
| Shakirova, Y | 1 |
| Swärd, K | 1 |
| Uvelius, B | 1 |
| Ekman, M | 1 |
| Russo, A | 1 |
| Castiglione, F | 1 |
| Salonia, A | 1 |
| Benigni, F | 1 |
| Rigatti, P | 1 |
| Montorsi, F | 1 |
| Andersson, KE | 2 |
| Hedlund, P | 1 |
| Andrade, EL | 1 |
| Forner, S | 1 |
| Bento, AF | 1 |
| Leite, DF | 1 |
| Dias, MA | 1 |
| Leal, PC | 1 |
| Koepp, J | 1 |
| Calixto, JB | 1 |
| Asfaw, TS | 1 |
| Hypolite, J | 1 |
| Northington, GM | 1 |
| Arya, LA | 1 |
| Wein, AJ | 1 |
| Malykhina, AP | 1 |
| Owen, SJ | 1 |
| Rose'Meyer, RB | 1 |
| Massa, HM | 1 |
| Eser, N | 1 |
| Göçmen, C | 1 |
| Erdoğan, S | 1 |
| Büyüknacar, HS | 1 |
| Kumcu, EK | 1 |
| Açıkalın, A | 1 |
| Önder, S | 1 |
| Schuler, V | 1 |
| Suter, K | 1 |
| Fürer, K | 1 |
| Eberli, D | 1 |
| Horst, M | 1 |
| Betschart, C | 1 |
| Brenneisen, R | 1 |
| Hamburger, M | 1 |
| Mennet, M | 1 |
| Schnelle, M | 1 |
| Simões-Wüst, AP | 1 |
| von Mandach, U | 1 |
| Leiria, LO | 1 |
| Sollon, C | 1 |
| Calixto, MC | 1 |
| Lintomen, L | 1 |
| Anhê, GF | 1 |
| De Nucci, G | 2 |
| Zanesco, A | 2 |
| Grant, AD | 1 |
| Valeri, A | 1 |
| Capasso, R | 1 |
| Valoti, M | 1 |
| Pessina, F | 1 |
| Soder, RP | 1 |
| Parajuli, SP | 1 |
| Hristov, KL | 1 |
| Svalø, J | 1 |
| Nordling, J | 1 |
| Bouchelouche, K | 1 |
| Korstanje, C | 1 |
| Bouchelouche, P | 1 |
| Li, L | 1 |
| Qiu, G | 1 |
| Hao, P | 1 |
| Song, B | 1 |
| Fabiyi, AC | 1 |
| Brading, AF | 1 |
| Stevens, LA | 1 |
| Chapple, CR | 1 |
| Ohtake, A | 1 |
| Saitoh, C | 1 |
| Yuyama, H | 1 |
| Ukai, M | 1 |
| Okutsu, H | 1 |
| Noguchi, Y | 1 |
| Hatanaka, T | 1 |
| Suzuki, M | 1 |
| Sato, S | 1 |
| Sasamata, M | 1 |
| Miyata, K | 1 |
| Lai, HH | 1 |
| Boone, TB | 1 |
| Thompson, TC | 1 |
| Smith, CP | 1 |
| Somogyi, GT | 1 |
| Zhu, HL | 1 |
| Iwasa, K | 1 |
| Tomoda, T | 1 |
| Aishima, M | 1 |
| Shibata, A | 1 |
| Naito, S | 1 |
| Teramoto, N | 1 |
| Bricola, AA | 1 |
| Báu, FR | 1 |
| Freitas, LL | 1 |
| Teixeira, SA | 1 |
| Muscará, MN | 1 |
| Abdalla, FM | 1 |
| Porto, CS | 1 |
| Nomoto, Y | 1 |
| Yoshida, A | 1 |
| Ikeda, S | 1 |
| Kamikawa, Y | 1 |
| Harada, K | 1 |
| Ohwatashi, A | 1 |
| Kawahira, K | 1 |
| Furuta, A | 1 |
| Suzuki, Y | 1 |
| Egawa, S | 1 |
| Chancellor, MB | 1 |
| Kobayashi, M | 1 |
| Nomura, M | 1 |
| Nishii, H | 1 |
| Matsumoto, S | 1 |
| Fujimoto, N | 1 |
| Matsumoto, T | 1 |
| Uno, T | 1 |
| Kobayashi, F | 1 |
| Ogata, A | 1 |
| Konomi, T | 1 |
1 review available for carbachol and Bladder, Overactive
| Article | Year |
|---|---|
[Pharmacological and clinical profile of imidafenacin developed as a new therapeutic agent for overactive bladder].
Topics: Acetylcholine; Animals; Carbachol; Clinical Trials as Topic; Drug-Related Side Effects and Adverse R | 2008 |
43 other studies available for carbachol and Bladder, Overactive
| Article | Year |
|---|---|
Inhibition of Full Smooth Muscle Contraction in Isolated Human Detrusor Tissues by Mirabegron Is Limited to Off-Target Inhibition of Neurogenic Contractions.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetanilides; Carbachol; Endothe | 2022 |
Mirabegron and solifenacin are effective for the management of the increased urinary frequency induced by psychological stress in female mice.
Topics: Acetanilides; Animals; Carbachol; Female; Mice; Muscarinic Antagonists; Solifenacin Succinate; Stres | 2022 |
Excitatory purinergic and cholinergic expression changed in a partial bladder outlet obstruction-induced overactive bladder rat model.
Topics: Animals; Carbachol; Cholinergic Agents; Female; Humans; Rats; Urinary Bladder; Urinary Bladder Neck | 2023 |
TAS-303 Ameliorates Carbachol-Induced Detrusor Overactivity in Rats, Revealing Its Therapeutic Potential for Overactive Bladder.
Topics: Adrenergic beta-3 Receptor Antagonists; Animals; Atropine; Carbachol; Dose-Response Relationship, Dr | 2020 |
Bladder overactivity induced by psychological stress in female mice is associated with enhanced bladder contractility.
Topics: Acetylcholine; Animals; Carbachol; Corticosterone; Female; Mice; Mice, Inbred C57BL; Muscarinic Agon | 2021 |
Detrusor contractility to parasympathetic mediators is differentially altered in the compensated and decompensated states of diabetic bladder dysfunction.
Topics: Adenosine Triphosphate; Animals; Carbachol; Cholinergic Agonists; Diabetes Mellitus, Experimental; D | 2019 |
Gap junction expression and the effects of gap junction inhibitors in overactive bladder models: does ovariectomy have a role?
Topics: Analysis of Variance; Animals; Blotting, Western; Carbachol; Connexin 43; Disease Models, Animal; Fe | 2013 |
Do β-adrenoceptor agonists induce homologous or heterologous desensitization in rat urinary bladder?
Topics: Adrenergic beta-2 Receptor Agonists; Adrenergic beta-3 Receptor Agonists; Adrenergic beta-Agonists; | 2014 |
Stimulation of large-conductance calcium-activated potassium channels inhibits neurogenic contraction of human bladder from patients with urinary symptoms and reverses acetic acid-induced bladder hyperactivity in rats.
Topics: Acetic Acid; Adult; Aged; Animals; Carbachol; Electric Stimulation; Female; Humans; Large-Conductanc | 2014 |
Izalpinin from fruits of Alpinia oxyphylla with antagonistic activity against the rat bladder contractility.
Topics: Alpinia; Carbachol; Cholinergic Agonists; Flavonoids; Fruit; Muscarinic Antagonists; Muscle Contract | 2014 |
The role of muscarinic receptor subtypes on carbachol-induced contraction of normal human detrusor and overactive detrusor associated with benign prostatic hyperplasia.
Topics: Carbachol; Dose-Response Relationship, Drug; Humans; In Vitro Techniques; Male; Muscarinic Agonists; | 2015 |
BK channel regulation by phosphodiesterase type 1: a novel signaling pathway controlling human detrusor smooth muscle function.
Topics: Aged; Carbachol; Cells, Cultured; Cyclic AMP-Dependent Protein Kinases; Drug Evaluation, Preclinical | 2016 |
Activation of bitter taste receptors (tas2rs) relaxes detrusor smooth muscle and suppresses overactive bladder symptoms.
Topics: Aged; Animals; Antirheumatic Agents; Carbachol; Cardiotonic Agents; Chloroquine; Female; Humans; Mal | 2016 |
Effects of Gegen (Puerariae lobatae Radix) water extract on improving detrusor overactivity in spontaneously hypertensive rats.
Topics: Animals; Benzofurans; Carbachol; China; Drugs, Chinese Herbal; Male; Muscle Contraction; Muscle, Smo | 2016 |
Long-term treatment with the beta-3 adrenoceptor agonist, mirabegron ameliorates detrusor overactivity and restores cyclic adenosine monophosphate (cAMP) levels in obese mice.
Topics: Acetanilides; Adrenergic beta-3 Receptor Agonists; Animals; Body Weight; Carbachol; Cyclic AMP; Cycl | 2017 |
The loss and progressive recovery of voiding after spinal cord interruption in rats is associated with simultaneous changes in autonomous contractile bladder activity.
Topics: Animals; Carbachol; Disease Models, Animal; Female; In Vitro Techniques; Muscarinic Agonists; Muscle | 2009 |
L-carnitine treatment partially restores urinary bladder function of streptozotocin diabetic rats.
Topics: Adenosine; Adenosine Triphosphate; Adrenergic beta-Agonists; Animals; Autonomic Nervous System; Bloo | 2008 |
Modification of rat detrusor muscle contraction by ascorbic acid and citric acid involving enhanced neurotransmitter release and Ca2+ influx.
Topics: Adenosine Triphosphate; Animals; Antioxidants; Ascorbic Acid; Atropine; Calcium Signaling; Carbachol | 2009 |
Effect of pre-contraction on β-adrenoceptor-mediated relaxation of rat urinary bladder.
Topics: Adrenergic beta-Agonists; Animals; Bradykinin; Carbachol; Colforsin; Dose-Response Relationship, Dru | 2009 |
The effects of chronic hyperlipidemia on bladder function in myocardial infarction-prone Watanabe heritable hyperlipidemic (WHHLMI) rabbits.
Topics: Animals; Atherosclerosis; Calcitonin Gene-Related Peptide; Carbachol; Cholinergic Agonists; Chronic | 2010 |
Effects of bladder outlet obstruction on properties of Ca2+-activated K+ channels in rat bladder.
Topics: Animals; Apamin; Carbachol; Charybdotoxin; Cholinergic Agonists; Female; Large-Conductance Calcium-A | 2010 |
AE9C90CB: a novel, bladder-selective muscarinic receptor antagonist for the treatment of overactive bladder.
Topics: Animals; Brain; Bridged Bicyclo Compounds, Heterocyclic; Carbachol; Cell Line, Transformed; CHO Cell | 2010 |
Biochemical and functional correlates of an increased membrane density of caveolae in hypertrophic rat urinary bladder.
Topics: Animals; Bradykinin; Carbachol; Caveolae; Caveolin 1; Cell Membrane; Female; Hypertrophy; In Vitro T | 2010 |
Effects of the gonadotropin-releasing hormone antagonist ganirelix on normal micturition and prostaglandin E(2)-induced detrusor overactivity in conscious female rats.
Topics: Administration, Intravesical; Animals; Blotting, Western; Carbachol; Cholinergic Agonists; Conscious | 2011 |
TRPA1 receptor modulation attenuates bladder overactivity induced by spinal cord injury.
Topics: Acetanilides; Acrolein; Animals; Ankyrins; Calcium Channels; Capsaicin; Carbachol; Disease Models, A | 2011 |
Acute colonic inflammation triggers detrusor instability via activation of TRPV1 receptors in a rat model of pelvic organ cross-sensitization.
Topics: Acute Disease; Animals; Carbachol; Cholinergic Agents; Colitis; Diterpenes; Electric Stimulation; Ma | 2011 |
Dietary phytoestrogens maintain contractile responses to carbachol with age in the female rat isolated bladder.
Topics: Age Factors; Animal Feed; Animals; Body Weight; Carbachol; Cholinergic Agonists; Female; Glycine max | 2011 |
Effect of silymarin on bladder overactivity in cyclophosphamide-induced cystitis rat model.
Topics: Animals; Carbachol; Cyclophosphamide; Cystitis; Disease Models, Animal; Female; Muscle Contraction; | 2012 |
Bryophyllum pinnatum inhibits detrusor contractility in porcine bladder strips--a pharmacological study towards a new treatment option of overactive bladder.
Topics: Animals; Carbachol; Cholinergic Agonists; Electric Stimulation; Kalanchoe; Mandelic Acids; Muscarini | 2012 |
Role of PKC and CaV1.2 in detrusor overactivity in a model of obesity associated with insulin resistance in mice.
Topics: Adiposity; Amlodipine; Animals; Body Weight; Calcium Channel Blockers; Calcium Channels, L-Type; Cal | 2012 |
Effects of St John's wort and its active constituents, hypericin and hyperforin, on isolated rat urinary bladder.
Topics: Animals; Anthracenes; Carbachol; Cell Membrane; Dose-Response Relationship, Drug; Electric Stimulati | 2012 |
SK channel-selective opening by SKA-31 induces hyperpolarization and decreases contractility in human urinary bladder smooth muscle.
Topics: Adult; Aged; Apamin; Benzothiazoles; Carbachol; Electric Stimulation; Female; Humans; Male; Membrane | 2013 |
The novel β3-adrenoceptor agonist mirabegron reduces carbachol-induced contractile activity in detrusor tissue from patients with bladder outflow obstruction with or without detrusor overactivity.
Topics: Acetanilides; Adrenergic beta-3 Receptor Agonists; Adrenergic beta-Agonists; Aged; Aged, 80 and over | 2013 |
Effect of partial bladder outlet obstruction on detrusor compliance, excitability and contractility in rats.
Topics: Animals; Carbachol; Compliance; Electric Stimulation; In Vitro Techniques; Male; Muscle Contraction; | 2006 |
The use of the isolated mouse whole bladder for investigating bladder overactivity.
Topics: Adenosine Triphosphate; Anesthetics, Local; Animals; Atropine; Bradykinin; Carbachol; Dose-Response | 2006 |
Human idiopathic and neurogenic overactive bladders and the role of M2 muscarinic receptors in contraction.
Topics: Adult; Aged; Benzofurans; Carbachol; Diamines; Dose-Response Relationship, Drug; Female; Humans; In | 2007 |
Pharmacological characterization of a new antimuscarinic agent, solifenacin succinate, in comparison with other antimuscarinic agents.
Topics: Animals; Atropine; Benzhydryl Compounds; Benzilates; Benzofurans; Binding, Competitive; Carbachol; C | 2007 |
Using caveolin-1 knockout mouse to study impaired detrusor contractility and disrupted muscarinic activity in the aging bladder.
Topics: Aging; Animals; Carbachol; Caveolin 1; Disease Models, Animal; Electric Stimulation; Male; Mice; Mic | 2007 |
Comparative studies of ZD0947, a novel ATP-sensitive K(+) channel opener, on guinea pig detrusor and aortic smooth muscles.
Topics: Animals; Aorta; Carbachol; Dihydropyridines; Electrophysiology; Guinea Pigs; Isometric Contraction; | 2008 |
Long-term nitric oxide deficiency causes muscarinic supersensitivity and reduces beta(3)-adrenoceptor-mediated relaxation, causing rat detrusor overactivity.
Topics: Adrenergic beta-3 Receptor Agonists; Adrenergic beta-Agonists; Animals; Carbachol; Inositol Phosphat | 2008 |
Effect of menthol on detrusor smooth-muscle contraction and the micturition reflex in rats.
Topics: Animals; Antipruritics; Capsaicin; Carbachol; Female; Menthol; Muscle Contraction; Muscle, Smooth; R | 2008 |
Association of overactive bladder and stress urinary incontinence in rats with pudendal nerve ligation injury.
Topics: Adrenergic alpha-Agonists; Animals; Capsaicin; Carbachol; Enzyme-Linked Immunosorbent Assay; Female; | 2008 |
Effect of eviprostat on bladder overactivity in an experimental cystitis rat model.
Topics: Animals; Antineoplastic Agents, Alkylating; Carbachol; Cholinergic Agonists; Cyclophosphamide; Cysti | 2008 |