carbachol and Asthma studies

Carbachol: A slowly hydrolyzed CHOLINERGIC AGONIST that acts at both MUSCARINIC RECEPTORS and NICOTINIC RECEPTORS.

Asthma: A form of bronchial disorder with three distinct components: airway hyper-responsiveness (RESPIRATORY HYPERSENSITIVITY), airway INFLAMMATION, and intermittent AIRWAY OBSTRUCTION. It is characterized by spasmodic contraction of airway smooth muscle, WHEEZING, and dyspnea (DYSPNEA, PAROXYSMAL).

Research Excerpts

Excerpt	Relevance	Reference
"Eight patients with mild extrinsic asthma participated in a double-blind randomized intraindividual cross-over study involving 6 weeks' treatment with twice daily oral theophylline (2 x 1 capsules = 800 mg/day Cronasma 400) and 6 weeks' treatment with twice daily inhaled budesonide (2 x 2 puffs = 0."	9.07	Theophylline vs. budesonide in the treatment of mild-to-moderate bronchial asthma. ( Herceg, R; Matthys, H; Müller, S, 1994)
"The potential influence of dietary caffeine on bronchoprovocation challenges with carbachol was examined in 7 patients with asymptomatic asthma."	9.06	Effect of dietary caffeine on airway reactivity in asthma. ( Bachofen, H; Crivelli, M; Jost, G; Preisig, R; Wahlländer, A, 1986)
"The protective effect on bronchospasm, induced by carbachol, of 2 puffs of fenoterol (200 micrograms), ipratropium bromide (80 micrograms) and Duovent (200 micrograms fenoterol + 80 micrograms ipratropium bromide) was compared in a group of 12 asthmatic patients."	9.06	Protective effect of Duovent on bronchospasm induced by carbachol in comparison with each of its components. ( Carnimeo, N; Carnimeo, R; D'Amore, ME; Foschino Barbaro, MP; Garofalo, G; Picca, V; Resta, O, 1986)
"Our purpose was to determine whether exposure to a realistic concentration of nitrogen dioxide (NO2) could increase the bronchial sensitivity of asthmatic patients to bronchoconstrictor agents."	9.04	Effect of short-term, low-level nitrogen dioxide exposure on bronchial sensitivity of asthmatic patients. ( Charpin, J; Gayrard, P; Grimaud, C; Massari, JP; Orehek, J, 1976)
"Epidemiologic studies have reported increased symptoms in young asthmatics when atmospheric pollutants containing nitrates and sulfates are elevated."	9.04	Airway reactivity to nitrates in normal and mild asthmatic subjects. ( Gibb, FR; Hyde, RW; Morrow, PE; Speers, DM; Swinburne, AJ; Utell, MJ, 1979)
" We have investigated the effects of cannabinoids on tracheal hyperreactivity and airway inflammation in dinitrofluorobenzene (DNFB)-induced experimental non-atopic asthma in mice."	7.83	The effect of cannabinoids on dinitrofluorobenzene-induced experimental asthma in mice. ( Bozkurt, TE; Durlu-Kandilci, NT; Kaya, Y; Onder, S; Sahin-Erdemli, I, 2016)
" In this study we examine the expression and function of FIZZ1 in an ovalbumin mouse model of asthma."	7.76	FIZZ1 potentiates the carbachol-induced tracheal smooth muscle contraction. ( Bowman, MR; Chen, H; Jacobson, BA; Mason, L; Wolf, SF, 2010)
"1 - 100 microM) inhibited carbachol- and high K +-induced muscle contractions in a concentration-dependent fashion, but did not affect basal muscle tension."	7.72	Inhibition of smooth muscle contraction by magnolol and honokiol in porcine trachea. ( Chan, MH; Chen, HH; Ko, CH; Lin, YR, 2003)
"For epidemiological purposes carbachol provocation test--like other unspecific bronchial provocation tests--is inappropriate as a single test to classify individuals as asthmatics."	7.68	[Longitudinal study of bronchial hyperreactivity using the carbachol test with school children]. ( Forster, J; Hendel-Kramer, A; Kühr, J; Weis, K, 1993)
"Inhalative bronchial provocation tests with pharmacodynamic substances, such as histamine, methacholine or carbachol are performed to confirm or exclude bronchial hyperreactivity."	7.68	[Carbachol inhalation provocation test using a reservoir method. 4-step test for the assessment of bronchial hyperreactivity]. ( Klein, G; Wagner-Heck, M; Zinn, CG, 1991)
"The authors revise their preliminary experiment with the bronchial provocation test using carbachol in 50 children of 5 to 14 years with non-IgE dependent bronchial asthma who had been asymptomatic for one year prior to the test in order to make a clinical evaluation of asthma."	7.67	[Persistence of nonspecific bronchial hyperreactivity in children with non-IgE dependent bronchial asthma: pharmacologic study with the Carbachol test]. ( Colás Sanz, C; Duce Gracía, F; Escuer Alarma, JL; Oliván Gonzalvo, G; Vecora Navarro, MD, 1988)
"To determine whether early and/or late asthmatic responses induced by toluene diisocyanate (TDI) are caused by a reflex mechanism involving stimulation of muscarinic receptors, we studied the effect of the muscarinic antagonist atropine on early and late airway response induced by TDI."	7.67	Atropine does not inhibit late asthmatic responses induced by toluene-diisocyanate in sensitized subjects. ( Bacci, E; Dente, FL; Fabbri, LM; Giuntini, C; Paggiaro, P; Pulerá, N; Rossi, O; Talini, D, 1987)
"In 50 patients with persistent cough suspected to be of asthmatic origin and in 16 healthy subjects, the bronchoconstrictor response to carbachol inhalation was determined by the method of Orehek."	7.67	[Bronchial reactions to carbachol inhalation in patients with a suspected diagnosis of cough due to asthma]. ( Bachofen, H; Crivelli, M; Zeller, C, 1985)
"Dose-response curves were established in asthmatics by using graded doses of aerosolized carbachol and specific airway conductance (SGaw) measurements."	7.66	Airway response of asthmatics to carbachol and to deep inspiration. ( Badier, M; Beaupre, A; Delpierre, S; Grimaud, C; Orehek, J, 1983)
"By constructing cumulative dose-response curves to inhaled carbachol in 12 normal and 17 asthmatic subjects with comparable baseline specific airway conductance, we have shown that there were wide variations among subjects in the dose of carbachol needed to cause a 25 per cent decrease in specific airway conductance (bronchial sensitivity) and in the slopes of the curves (bronchial reactivity)."	7.65	Airway response to carbachol in normal and asthmatic subjects: distinction between bronchial sensitivity and reactivity. ( Charpin, J; Gayrard, P; Grimaud, C; Orehek, J; Smith, AP, 1977)
"The carbachol challenge was repeated 6-18 months later."	5.27	Asthma without airway hyperresponsiveness to carbachol. ( Arnaud, A; Charpin, J; Giffon, E; Orehek, J; Vervloet, D, 1987)
"The study was conducted to characterize the action of NaF, which had relaxing property in carbachol precontracted isolated bovine bronchus, on airway responsiveness challenged by acetylcholine receptor agonists in rats and asthmatic humans."	5.10	Inhaled sodium fluoride decreases airway responsiveness to acetylcholine analogs in vivo. ( Guénard, H; Rouatbi, S; Tabka, Z; Zhao, W, 2002)
" Comparing the measured variables (maximal deviation from base-line values of Raw and FEV1) during carbachol provocation in the afternoon under Nebivolol and placebo with the values in the morning before any medication (base-line values), there were also no significant detectable differences indicating an increase of bronchial hyperreactivity under Nebivolol treatment."	5.09	[Nebivolol (nebilet) a beta blocker of the third generation--also for patients with obstructive lung diseases?]. ( Giebelhaus, V; Matthys, H; von Fallois, J, 2001)
" Therefore, we decided to study nonspecific bronchial responsiveness following cumulative doses of inhaled carbachol in 44 children with clinical asthma (CA group), 44 children with chronic cough (CC group), 38 children with wheezy bronchitis in the first 2 years of life (WB group), and 40 controls."	5.09	Bronchial challenge with carbachol in 3-6-year-old children: body plethysmography assessments. ( Badier, M; Dubus, JC; Guillot, C, 1999)
"The aim of this study was to establish a relationship between bronchial hyperreactivity to carbachol and reflex bronchomotor response to the activation of cold receptors in the nose, and also to examine whether any differences exist between asthmatic patients with or without symptoms of rhinitis."	5.08	Nasal eupnoeic inhalation of cold, dry air increases airway resistance in asthmatic patients. ( Burnet, H; Fontanari, P; Jammes, Y; Zattara-Hartmann, MC, 1997)
" The aim of the study was to determine the carbachol and albuterol responsiveness in treated and untreated asthmatic and allergic children exposed to environmental tobacco smoke assessed by urinary cotinine measurements."	5.08	Possible interaction between exposure to environmental tobacco smoke and therapy in children with asthma. ( Badier, M; Bruguerolle, B; Dubus, JC; Guillot, C; Oddoze, C, 1998)
"Eight patients with mild extrinsic asthma participated in a double-blind randomized intraindividual cross-over study involving 6 weeks' treatment with twice daily oral theophylline (2 x 1 capsules = 800 mg/day Cronasma 400) and 6 weeks' treatment with twice daily inhaled budesonide (2 x 2 puffs = 0."	5.07	Theophylline vs. budesonide in the treatment of mild-to-moderate bronchial asthma. ( Herceg, R; Matthys, H; Müller, S, 1994)
"The potential influence of dietary caffeine on bronchoprovocation challenges with carbachol was examined in 7 patients with asymptomatic asthma."	5.06	Effect of dietary caffeine on airway reactivity in asthma. ( Bachofen, H; Crivelli, M; Jost, G; Preisig, R; Wahlländer, A, 1986)
"The protective effect on bronchospasm, induced by carbachol, of 2 puffs of fenoterol (200 micrograms), ipratropium bromide (80 micrograms) and Duovent (200 micrograms fenoterol + 80 micrograms ipratropium bromide) was compared in a group of 12 asthmatic patients."	5.06	Protective effect of Duovent on bronchospasm induced by carbachol in comparison with each of its components. ( Carnimeo, N; Carnimeo, R; D'Amore, ME; Foschino Barbaro, MP; Garofalo, G; Picca, V; Resta, O, 1986)
"The effect of premedication with cromolyn 40 mg on the bronchial response to inhaled carbachol was investigated in four atopic and four non-atopic subjects with mild asthma."	5.05	Effect of cromolyn on carbachol-induced bronchoconstriction. ( Fabbri, LM; Hendrick, DJ; Mapp, CE, 1983)
"Epidemiologic studies have reported increased symptoms in young asthmatics when atmospheric pollutants containing nitrates and sulfates are elevated."	5.04	Airway reactivity to nitrates in normal and mild asthmatic subjects. ( Gibb, FR; Hyde, RW; Morrow, PE; Speers, DM; Swinburne, AJ; Utell, MJ, 1979)
"Our purpose was to determine whether exposure to a realistic concentration of nitrogen dioxide (NO2) could increase the bronchial sensitivity of asthmatic patients to bronchoconstrictor agents."	5.04	Effect of short-term, low-level nitrogen dioxide exposure on bronchial sensitivity of asthmatic patients. ( Charpin, J; Gayrard, P; Grimaud, C; Massari, JP; Orehek, J, 1976)
"Ovalbumin (OVA)-sensitized rats were actively challenged with saline or OVA to study airway hyper-responsiveness after oral treatment with saline or Jp."	3.85	Inhibitory effects of a standardized extract of Justicia pectoralis in an experimental rat model of airway hyper-responsiveness. ( Aragão, KS; Batista-Lima, FJ; Brito, TS; Ferreira, LC; Fonseca, FN; Havt, A; Leal, LKAM; Magalhães, PJC; Moura, CTM; Roque, CR; Silva, AAV, 2017)
" We have investigated the effects of cannabinoids on tracheal hyperreactivity and airway inflammation in dinitrofluorobenzene (DNFB)-induced experimental non-atopic asthma in mice."	3.83	The effect of cannabinoids on dinitrofluorobenzene-induced experimental asthma in mice. ( Bozkurt, TE; Durlu-Kandilci, NT; Kaya, Y; Onder, S; Sahin-Erdemli, I, 2016)
" Pulmonary fibroblasts of asthmatic (n = 9) and non-asthmatic (n = 8) subjects were stimulated with the muscarinic receptor agonist carbachol and interleukin-1β (IL-1 beta) in presence or absence of tiotropium or olodaterol alone, or their combination."	3.80	Tiotropium sustains the anti-inflammatory action of olodaterol via the cyclic AMP pathway. ( Borger, P; Costa, L; Keglowich, L; Lardinois, D; Miglino, N; Roth, M; Tamm, M; Zhong, J, 2014)
"Inhalation of JMF2-1, an analog of lidocaine with reduced anesthetic activity, prevents airway contraction and lung inflammation in experimental asthma models."	3.78	Two for one: cyclic AMP mediates the anti-inflammatory and anti-spasmodic properties of the non-anesthetic lidocaine analog JMF2-1. ( Coelho, LP; Cordeiro, RS; da Costa, JC; Martins, MA; Olsen, PC; Silva, PM, 2012)
" In this study we examine the expression and function of FIZZ1 in an ovalbumin mouse model of asthma."	3.76	FIZZ1 potentiates the carbachol-induced tracheal smooth muscle contraction. ( Bowman, MR; Chen, H; Jacobson, BA; Mason, L; Wolf, SF, 2010)
"We have investigated the mechanisms of action of luteolin, a flavone found in Perilla frutescens, a Chinese herbal medicine for treating asthma."	3.73	Mechanisms of relaxant action of luteolin in isolated guinea pig trachea. ( Chang, JP; Chen, TT; Ko, WC; Leu, IJ; Shih, CM, 2005)
"1 - 100 microM) inhibited carbachol- and high K +-induced muscle contractions in a concentration-dependent fashion, but did not affect basal muscle tension."	3.72	Inhibition of smooth muscle contraction by magnolol and honokiol in porcine trachea. ( Chan, MH; Chen, HH; Ko, CH; Lin, YR, 2003)
"The clinical characteristics of idiopathic nasal polyposis in children (11 males and nine females; median: 12 years; range: 8-15 years) were very similar to those observed in adults (median: 50 years), in particular the relation to asthma (ten of 20 cases) and aspirin intolerance (two Fernand-Widal syndromes of 20 cases)."	3.70	[Does idiopathic naso-sinusal polyposis exist in children?]. ( Coffinet, L; Derelle, J; Jankowski, R; Pialoux, R, 1999)
" Bronchial challenge tests were carried out with cumulative doses of inhaled carbachol in 10 healthy children (aged 7-14 yrs) and 50 asthmatic children (aged 5-15 yrs)."	3.69	Oscillatory pressure transients after flow interruption during bronchial challenge test in children. ( Frey, U; Kraemer, R, 1997)
"Inhaled adenosine induces bronchoconstriction in asthmatic and allergic subjects but not in nonasthmatics."	3.69	Adenosine-induced bronchoconstriction in conscious hyperresponsive and sensitized guinea pigs. ( Broadley, KJ; Thorne, JR, 1994)
"Bronchial reactivity to carbachol, estimated by the PD65, the provocation dose of inhaled carbachol inducing a 65% increase of baseline respiratory resistance, was measured in 355 asthmatic children (age 8."	3.68	Interfering factors to sensitivity and specificity of bronchial reactivity in children. ( Gschwend-Eigenmann, S; Kraemer, R; Schöni, MH; Sommer, CW; Stadler, BM, 1993)
"Inhalative bronchial provocation tests with pharmacodynamic substances, such as histamine, methacholine or carbachol are performed to confirm or exclude bronchial hyperreactivity."	3.68	[Carbachol inhalation provocation test using a reservoir method. 4-step test for the assessment of bronchial hyperreactivity]. ( Klein, G; Wagner-Heck, M; Zinn, CG, 1991)
"For epidemiological purposes carbachol provocation test--like other unspecific bronchial provocation tests--is inappropriate as a single test to classify individuals as asthmatics."	3.68	[Longitudinal study of bronchial hyperreactivity using the carbachol test with school children]. ( Forster, J; Hendel-Kramer, A; Kühr, J; Weis, K, 1993)
" In 40 stable asthmatic children (age, 5-16 yr) we performed challenges with doubling concentrations of inhaled carbachol (0."	3.68	Correspondence between forced oscillation and body plethysmography during bronchoprovocation with carbachol in children. ( Berdel, D; Buhr, W; Jörres, R; Làndsér, FJ, 1990)
"To determine significant thresholds obtained by bronchial challenge tests in children for assessment of bronchial reactivity, changes of respiratory resistance (Rint) induced by inhaled carbachol were evaluated in 20 asthmatic children (10 boys and 10 girls, mean age 9."	3.68	Specific approach on dose-response curves to inhaled carbachol assessed by the interruption technique in children. ( Frey, U; Kraemer, R; Schönli, MH; Sommer, CW, 1993)
" The autoradiographic distribution of alpha 1-adrenoceptors was investigated in non-diseased and asthmatic human lung by use of [3H]-prazosin (H-PZ)."	3.67	Alpha 1-adrenoceptor function and autoradiographic distribution in human asthmatic lung. ( Goldie, RG; Paterson, JW; Rigby, PJ; Spina, D, 1989)
"To determine whether early and/or late asthmatic responses induced by toluene diisocyanate (TDI) are caused by a reflex mechanism involving stimulation of muscarinic receptors, we studied the effect of the muscarinic antagonist atropine on early and late airway response induced by TDI."	3.67	Atropine does not inhibit late asthmatic responses induced by toluene-diisocyanate in sensitized subjects. ( Bacci, E; Dente, FL; Fabbri, LM; Giuntini, C; Paggiaro, P; Pulerá, N; Rossi, O; Talini, D, 1987)
"The authors revise their preliminary experiment with the bronchial provocation test using carbachol in 50 children of 5 to 14 years with non-IgE dependent bronchial asthma who had been asymptomatic for one year prior to the test in order to make a clinical evaluation of asthma."	3.67	[Persistence of nonspecific bronchial hyperreactivity in children with non-IgE dependent bronchial asthma: pharmacologic study with the Carbachol test]. ( Colás Sanz, C; Duce Gracía, F; Escuer Alarma, JL; Oliván Gonzalvo, G; Vecora Navarro, MD, 1988)
"Pupillary responses to phenylephrine and carbachol and airway reactivity were determined in 19 drug-free persons with mild allergic asthma, 21 nonatopic control subjects, and six asymptomatic atopic control subjects."	3.67	Pupillary responses and airway reactivity in asthma. ( Davis, PB, 1986)
"We tested bronchial reactivity to carbachol in 50 asthmatics, healthy parents of 40 asthmatic children, and 70 healthy subjects with no personal or family history of asthma."	3.67	Genetic factors in nonspecific bronchial hyperreactivity. An epidemiologic study. ( Fumi, F; Longo, G; Poli, F; Strinati, R, 1987)
"Nine children, sensitized to grass pollens, with seasonal rhinitis and mild asthma underwent bronchial challenge with carbachol and EIA test repeatedly either during a pre-seasonal or in seasonal period."	3.67	Influence of aeroallergens on bronchial reactivity in children sensitized to grass pollens. ( Barbato, A; Marcer, G; Mesirca, P; Norbiato, M; Pesenti, P; Pisetta, F; Ragusa, A, 1986)
"In 50 patients with persistent cough suspected to be of asthmatic origin and in 16 healthy subjects, the bronchoconstrictor response to carbachol inhalation was determined by the method of Orehek."	3.67	[Bronchial reactions to carbachol inhalation in patients with a suspected diagnosis of cough due to asthma]. ( Bachofen, H; Crivelli, M; Zeller, C, 1985)
" Respiratory health was evaluated by determination of bronchial reactivity to Carbachol in 5 diagnostic groups (healthy: 109; healthy with positive family history of atopy: 60; allergic but not asthma: 59; asthma: 55; and "unclear cough": 29) by the technique of group specific sampling."	3.67	[Effect of air pollutant burden on healthy children and children with lung diseases in southern Ticino]. ( D'Apuzzo, V; Gschwend-Eigenmann, S; Kraemer, R; Schöni, MH, 1989)
"Modifications of the mechanical ventilatory function in 18 atopic asthmatic patients challenged with carbachol and mites are studied."	3.66	[Modifications of respiratory mechanics of asthmatics challenged with cholinergics and allergens]. ( Calvayrac, P; Cannet, G; Clauzel, AM; Friemel, F; Garcelon, M; Michel, FB, 1983)
"Dose-response curves were established in asthmatics by using graded doses of aerosolized carbachol and specific airway conductance (SGaw) measurements."	3.66	Airway response of asthmatics to carbachol and to deep inspiration. ( Badier, M; Beaupre, A; Delpierre, S; Grimaud, C; Orehek, J, 1983)
"The influence of oxyfedrine (beta-adrenoagonist) and carbocholine (cholinoagonist) on the functional activity of Con A-induced suppressor T-lymphocytes in healthy persons and in bronchial asthma patients was studied."	3.66	[Suppressor activity changes in human T-lymphocytes as affected by adreno- and cholinotropic substances]. ( Gol'dshteĭn, MM; Poriadin, GV; Salmasi, ZhM, 1983)
"By repeated inhalant carbachol provocation tests on 13 normal and 13 asthmatic subjects, we investigated the effect of ketotifen (as compared with placebo) on the cholinergic responsiveness of the airways."	3.66	Effects of ketotifen on cholinergic induced airway obstruction. ( Klein, G; Köhler, D; Matthys, H; Schiess, W; Schulz, N, 1983)
"We have studied 26 asthmatic patients in whom deep inspiration induced a transient but marked bronchodilatation when carbachol-induced bronchoconstriction was present."	3.66	Factors influencing the bronchodilator effect of a deep inspiration in asthmatic patients with provoked bronchoconstriction. ( Beaupré, A; Orehek, J, 1982)
"By constructing cumulative dose-response curves to inhaled carbachol in 12 normal and 17 asthmatic subjects with comparable baseline specific airway conductance, we have shown that there were wide variations among subjects in the dose of carbachol needed to cause a 25 per cent decrease in specific airway conductance (bronchial sensitivity) and in the slopes of the curves (bronchial reactivity)."	3.65	Airway response to carbachol in normal and asthmatic subjects: distinction between bronchial sensitivity and reactivity. ( Charpin, J; Gayrard, P; Grimaud, C; Orehek, J; Smith, AP, 1977)
" This study was performed to evaluate the relative sensitivity of the (FEV1)-25 and the classical FEV1 in detecting airway obstruction caused by an inhaled carbachol aerosol in 20 asthmatic subjects."	3.65	A new simple spirometric index for use with bronchial provocation tests. ( Charpin, J; Grimaud, C; Orehek, J, 1977)
"Cumulative dose-response curves to carbachol given by aerosol were established using plethysmographic measurements of specific airways resistance (SRaw) in 10 patients with asthma and five healthy subjects."	3.65	Effect of maximal respiratory manoeuvres on bronchial sensitivity of asthmatic patients as compared to normal people. ( Charpin, J; Gayrard, P; Grimaud, C; Orehek, J, 1975)
"Senicapoc-treated sheep also demonstrated reduced airway hyperresponsiveness, requiring a significantly higher dose of carbachol to increase resistance by 100% compared to allergen-challenged vehicle-control sheep (20±5 vs."	1.39	K(Ca)3.1 channel-blockade attenuates airway pathophysiology in a sheep model of chronic asthma. ( Barcham, G; Barker, D; Bradding, P; Castle, N; Koumoundouros, E; Snibson, K; Sum, G; Van Der Velden, J; Wulff, H, 2013)
"Treatment with rosiglitazone preserved salbutamol relaxant activity, mitigated carbachol hyperresponsiveness and partially restored β₂-adrenoceptor binding sites in tracheal tissues from homologously desensitized animals."	1.37	Rosiglitazone reverses salbutamol-induced β(2) -adrenoceptor tolerance in airway smooth muscle. ( Adinolfi, B; Bardelli, C; Betti, L; Breschi, MC; Brunelleschi, S; Fabbrini, L; Fogli, S; Giannaccini, G; Lucacchini, A; Mariotti, V; Melissari, E; Pellegrini, S; Stefanelli, F, 2011)
" Bronchial lability was characterized by (1) variability in mean daily peak expiratory flow rate and (2) bronchial responsiveness to either carbachol (as assessed by the threshold dose and the slope of the dose-response curve) or salbutamol (as assessed by the threshold dose and maximal response)."	1.28	Relationship between spontaneous dyspnoea and lability of airway obstruction in asthma. ( Lockhart, A; Marsac, J; Peiffer, C; Razzouk, H; Toumi, M, 1992)
"To examine for a relationship between in vivo nonspecific bronchial reactivity to histamine and in vitro smooth muscle response to histamine, we performed inhalation dose-response curves prior to lung surgery in 12 patients and compared this with their bronchial smooth muscle response in vitro."	1.27	A comparison of in vivo and in vitro human airway reactivity to histamine. ( Armour, CL; Chan, N; Hogg, JC; Lazar, NM; Paré, PD; Schellenberg, RR; Taylor, SM, 1984)
"The carbachol challenge was repeated 6-18 months later."	1.27	Asthma without airway hyperresponsiveness to carbachol. ( Arnaud, A; Charpin, J; Giffon, E; Orehek, J; Vervloet, D, 1987)
" In order to eliminate the possible influence of airway obstruction on aerosol distribution and deposition, we selected 5 asthmatic subjects with normal respiratory function (spirometry, SRaw, nitrogen washout and closing volume); furthermore, non-cumulative dose-response curves were obtained (i."	1.27	Different bronchoconstrictor effects of carbachol boluses inhaled near residual volume or total lung capacity. ( Badier, M; Gayrard, P; Orehek, J; Vervloet, D, 1987)
" In each airway segment, cumulative dose-response effects of ovalbumin were obtained in the absence and presence of a maximally effective concentration of a beta adrenergic receptor agonist, sulfonterol."	1.26	Parainfluenza 3 infection blocks the ability of a beta adrenergic receptor agonist to inhibit antigen-induced contraction of guinea pig isolated airway smooth muscle. ( Ain-Shoka, AA; Buckner, CK; Busse, WW; Clayton, DE; Dick, EC; Shult, P, 1981)

Timeframe	Studies, this research(%)	All Research%
pre-1990	74 (47.44)	18.7374
1990's	41 (26.28)	18.2507
2000's	18 (11.54)	29.6817
2010's	20 (12.82)	24.3611
2020's	3 (1.92)	2.80

Trial			Phase	Enrollment	Study Type	Start Date	Status
[NCT00005280]				0 participants	Observational	1972-06-30	Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Article	Year
Haemophilus influenzae and the beta-adrenergic system: a review. Veterinary research communications, 1984, Volume: 8, Issue:1 Topics: Animals; Antigens, Bacterial; Asthma; Carbachol; Guinea Pigs; Haemophilus influenzae; Histamine Rele	1984
[Inhalation provocation tests in the diagnosis of bronchial asthma]. Polski tygodnik lekarski (Warsaw, Poland : 1960), 1982, Aug-02, Volume: 37, Issue:26 Topics: Albuterol; Allergens; Asthma; Bronchi; Bronchial Provocation Tests; Carbachol; Evaluation Studies as	1982
[Chemical air pollution and bronchial asthma]. La Revue du praticien, 1976, Jun-11, Volume: 26, Issue:33 Topics: Air Pollution; Airway Resistance; Asthma; Carbachol; Humans; Nitrous Oxide; Sulfur Oxides; Vehicle E	1976
Modulation of airway hyperresponsiveness. Annals of allergy, 1988, Volume: 60, Issue:5 Topics: Acetylcholine; Airway Resistance; Asthma; Carbachol; Histamine; Humans; Methacholine Compounds; Prop	1988
In-vivo and in-vitro responsiveness of bronchial smooth muscle. Bulletin europeen de physiopathologie respiratoire, 1986, Volume: 22 Suppl 7 Topics: Airway Resistance; Albuterol; Animals; Asthma; Atropine; Atropine Derivatives; Bronchi; Carbachol; D	1986

Article	Year
Salmeterol or doxycycline do not inhibit acute bronchospasm and airway inflammation in cats with experimentally-induced asthma. Veterinary journal (London, England : 1997), 2012, Volume: 192, Issue:1 Topics: Administration, Inhalation; Administration, Oral; Adrenergic beta-2 Receptor Agonists; Albuterol; An	2012
Inhaled sodium fluoride decreases airway responsiveness to acetylcholine analogs in vivo. Respiratory physiology & neurobiology, 2002, Aug-01, Volume: 131, Issue:3 Topics: Acetylcholine; Administration, Inhalation; Adult; Airway Resistance; Animals; Asthma; Blood Pressure	2002
Effect of cromolyn on carbachol-induced bronchoconstriction. Annals of allergy, 1983, Volume: 50, Issue:3 Topics: Adult; Asthma; Bronchial Diseases; Carbachol; Constriction, Pathologic; Cromolyn Sodium; Female; For	1983
Airway responses to sulfate and sulfuric acid aerosols in asthmatics. An exposure-response relationship. The American review of respiratory disease, 1983, Volume: 128, Issue:3 Topics: Adult; Aerosols; Air Pollutants; Asthma; Carbachol; Dose-Response Relationship, Drug; Humans; Lung V	1983
Theophylline vs. budesonide in the treatment of mild-to-moderate bronchial asthma. Respiration; international review of thoracic diseases, 1994, Volume: 61, Issue:5 Topics: Administration, Inhalation; Administration, Oral; Adult; Asthma; Bronchial Provocation Tests; Bronch	1994
[Modification of nonspecific bronchial hyperreactivity to cold air hyperventilation and carbachol by nedocromil and budesonide]. Pneumologie (Stuttgart, Germany), 1993, Volume: 47, Issue:3 Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Asthma; Bronchial Hyperreactivity; Bronchial Provoca	1993
Detection of GM-CSF in asthmatic bronchial epithelium and decrease by inhaled corticosteroids. The American review of respiratory disease, 1993, Volume: 147, Issue:6 Pt 1 Topics: Administration, Inhalation; Adult; Asthma; Beclomethasone; Biopsy; Bronchi; Bronchoscopy; Carbachol;	1993
Nasal eupnoeic inhalation of cold, dry air increases airway resistance in asthmatic patients. The European respiratory journal, 1997, Volume: 10, Issue:10 Topics: Administration, Inhalation; Adult; Airway Resistance; Analysis of Variance; Asthma; Bronchial Hyperr	1997
Possible interaction between exposure to environmental tobacco smoke and therapy in children with asthma. Clinical science (London, England : 1979), 1998, Volume: 95, Issue:2 Topics: Adolescent; Albuterol; Asthma; Biomarkers; Bronchial Hyperreactivity; Bronchial Provocation Tests; B	1998
Bronchial challenge with carbachol in 3-6-year-old children: body plethysmography assessments. Pediatric pulmonology, 1999, Volume: 27, Issue:2 Topics: Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchitis; Bronchoconstrictor Agent	1999
[Nebivolol (nebilet) a beta blocker of the third generation--also for patients with obstructive lung diseases?]. Zeitschrift fur Kardiologie, 2001, Volume: 90, Issue:10 Topics: Administration, Oral; Adolescent; Adrenergic beta-Antagonists; Adult; Aged; Asthma; Benzopyrans; Bro	2001
Airway reactivity to nitrates in normal and mild asthmatic subjects. Journal of applied physiology: respiratory, environmental and exercise physiology, 1979, Volume: 46, Issue:1 Topics: Adolescent; Adult; Aerosols; Air Pollutants; Asthma; Carbachol; Dose-Response Relationship, Drug; Fo	1979
Effect of short-term, low-level nitrogen dioxide exposure on bronchial sensitivity of asthmatic patients. The Journal of clinical investigation, 1976, Volume: 57, Issue:2 Topics: Adolescent; Adult; Airway Resistance; Asthma; Bronchi; Carbachol; Dose-Response Relationship, Drug;	1976
Protective effect of Duovent on bronchospasm induced by carbachol in comparison with each of its components. Respiration; international review of thoracic diseases, 1986, Volume: 50 Suppl 2 Topics: Adolescent; Adult; Asthma; Atropine Derivatives; Bronchial Provocation Tests; Bronchial Spasm; Carba	1986
Effects of regular inhalation of beclomethasone dipropionate and sodium cromoglycate on bronchial hyperreactivity in asthmatic children. Acta paediatrica Scandinavica, 1987, Volume: 76, Issue:1 Topics: Administration, Inhalation; Adolescent; Airway Resistance; Asthma; Beclomethasone; Bronchi; Carbacho	1987
Effect of dietary caffeine on airway reactivity in asthma. Respiration; international review of thoracic diseases, 1986, Volume: 50, Issue:4 Topics: Administration, Oral; Adult; Airway Resistance; Asthma; Biotransformation; Bronchial Provocation Tes	1986
Effect of diltiazem on histamine- and carbachol-induced bronchospasm in normal and asthmatic subjects. Chest, 1985, Volume: 87, Issue:2 Topics: Adult; Asthma; Benzazepines; Bronchial Spasm; Calcium; Carbachol; Clinical Trials as Topic; Diltiaze	1985
Non-allergic asthma and conditioning process. Annals of allergy, 1974, Volume: 32, Issue:5 Topics: Adolescent; Asthma; Bronchial Spasm; Carbachol; Child; Clinical Trials as Topic; Conditioning, Psych	1974

Article	Year
Therapeutic potential of Ceratonia siliqua extract for the management of asthma and hypertension. Cellular and molecular biology (Noisy-le-Grand, France), 2022, Feb-04, Volume: 67, Issue:5 Topics: Animals; Asthma; Carbachol; Fabaceae; Hypertension; Plant Extracts; Rabbits; Rats	2022
Starving a Cell Promotes Airway Smooth Muscle Relaxation: Inhibition of Glycolysis Attenuates Excitation-Contraction Coupling. American journal of respiratory cell and molecular biology, 2023, Volume: 68, Issue:1 Topics: Adenosine Triphosphate; Asthma; Carbachol; Cells, Cultured; Glucose; Glycolysis; Humans; Lung; Muscl	2023
Rhinovirus C15 Induces Airway Hyperresponsiveness via Calcium Mobilization in Airway Smooth Muscle. American journal of respiratory cell and molecular biology, 2020, Volume: 62, Issue:3 Topics: Asthma; Calcium Signaling; Carbachol; Cells, Cultured; Chemokine CXCL10; Enterovirus; Enterovirus In	2020
Bronchodilator effects of Lignosus rhinocerotis extract on rat isolated airways is linked to the blockage of calcium entry. Phytomedicine : international journal of phytotherapy and phytopharmacology, 2018, Mar-15, Volume: 42 Topics: Animals; Asthma; Bronchi; Bronchodilator Agents; Calcium; Carbachol; Male; Muscle Contraction; Organ	2018
Obesity increases airway smooth muscle responses to contractile agonists. American journal of physiology. Lung cellular and molecular physiology, 2018, 11-01, Volume: 315, Issue:5 Topics: Adult; Asthma; Calcium; Carbachol; Cardiotonic Agents; Case-Control Studies; Cells, Cultured; Female	2018
Up-regulation of Rac1 in the bronchial smooth muscle of murine experimental asthma. Basic & clinical pharmacology & toxicology, 2019, Volume: 125, Issue:1 Topics: Animals; Asthma; Bronchi; Carbachol; Disease Models, Animal; Humans; Male; Mice; Muscle Contraction;	2019
Treatment with Paracetamol is not Associated with Increased Airway Sensitivity and Risk of Asthma in Rats. Current drug safety, 2019, Volume: 14, Issue:2 Topics: Acetaminophen; Alanine Transaminase; Animals; Aspartate Aminotransferases; Asthma; Carbachol; Glutat	2019
Increased Rac1 Activation in the Enhanced Carbachol-Induced Bronchial Smooth Muscle Contraction of Repeatedly Antigen-Challenged Mice. Biological & pharmaceutical bulletin, 2019, Sep-01, Volume: 42, Issue:9 Topics: Aminoquinolines; Animals; Antigens; Asthma; Bronchi; Carbachol; Guanine Nucleotide Exchange Factors;	2019
K(Ca)3.1 channel-blockade attenuates airway pathophysiology in a sheep model of chronic asthma. PloS one, 2013, Volume: 8, Issue:6 Topics: Acetamides; Airway Remodeling; Airway Resistance; Animals; Asthma; Blood Vessels; Bronchoalveolar La	2013
Tiotropium sustains the anti-inflammatory action of olodaterol via the cyclic AMP pathway. Pulmonary pharmacology & therapeutics, 2014, Volume: 27, Issue:1 Topics: Adrenergic beta-2 Receptor Agonists; Adult; Aged; Anti-Inflammatory Agents; Asthma; Benzoxazines; Br	2014
Studies on antidiarrhoeal, antispasmodic and bronchodilator activities of Operculina turpethum Linn. BMC complementary and alternative medicine, 2014, Dec-12, Volume: 14 Topics: Animals; Antidiarrheals; Asthma; Bronchodilator Agents; Calcium; Calcium Channel Blockers; Carbachol	2014
The effect of cannabinoids on dinitrofluorobenzene-induced experimental asthma in mice. Respiratory physiology & neurobiology, 2016, Volume: 231 Topics: Acetylcholine; Animals; Anti-Asthmatic Agents; Asthma; Atropine; Cannabinoid Receptor Agonists; Cann	2016
Inhibitory effects of a standardized extract of Justicia pectoralis in an experimental rat model of airway hyper-responsiveness. The Journal of pharmacy and pharmacology, 2017, Volume: 69, Issue:6 Topics: Animals; Asthma; Bronchoalveolar Lavage Fluid; Calcium; Carbachol; Justicia; Male; Models, Animal; O	2017
FIZZ1 potentiates the carbachol-induced tracheal smooth muscle contraction. The European respiratory journal, 2010, Volume: 36, Issue:5 Topics: Animals; Asthma; Bronchoalveolar Lavage Fluid; Carbachol; Cholinergic Agonists; Disease Models, Anim	2010
Rosiglitazone reverses salbutamol-induced β(2) -adrenoceptor tolerance in airway smooth muscle. British journal of pharmacology, 2011, Volume: 162, Issue:2 Topics: Adrenergic beta-2 Receptor Agonists; Albuterol; Animals; Asthma; Carbachol; Cells, Cultured; Dexamet	2011
The calcium channel blocking and phosphodiesterase inhibitory activities of the extract of Andropogon muricatus explains its medicinal use in airways disorders. Phytotherapy research : PTR, 2012, Volume: 26, Issue:8 Topics: Andropogon; Animals; Asthma; Calcium Channel Blockers; Calcium Channels; Carbachol; Guinea Pigs; In	2012
An RGS4-mediated phenotypic switch of bronchial smooth muscle cells promotes fixed airway obstruction in asthma. PloS one, 2012, Volume: 7, Issue:1 Topics: Airway Obstruction; Asthma; Bronchi; Bronchoconstriction; Carbachol; Cell Proliferation; Excitation	2012
Inhibition of allergic airway responses by heparin derived oligosaccharides: identification of a tetrasaccharide sequence. Respiratory research, 2012, Jan-23, Volume: 13 Topics: Animals; Anti-Asthmatic Agents; Anticoagulants; Antigens, Helminth; Ascaris suum; Asthma; Bronchoalv	2012
Airways dilate to simulated inspiratory but not expiratory manoeuvres. The European respiratory journal, 2012, Volume: 40, Issue:2 Topics: Animals; Asthma; Bronchial Provocation Tests; Bronchodilator Agents; Carbachol; Endoscopy; Exhalatio	2012
Trichostatin A abrogates airway constriction, but not inflammation, in murine and human asthma models. American journal of respiratory cell and molecular biology, 2012, Volume: 46, Issue:2 Topics: Animals; Asthma; Blotting, Western; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Calcium; Carb	2012
Force oscillations simulating breathing maneuvers do not prevent force adaptation. American journal of respiratory cell and molecular biology, 2012, Volume: 47, Issue:1 Topics: Adaptation, Physiological; Animals; Asthma; Carbachol; Electric Stimulation; In Vitro Techniques; Mu	2012
Two for one: cyclic AMP mediates the anti-inflammatory and anti-spasmodic properties of the non-anesthetic lidocaine analog JMF2-1. European journal of pharmacology, 2012, Apr-05, Volume: 680, Issue:1-3 Topics: Adenylyl Cyclases; Animals; Anti-Inflammatory Agents; Apoptosis; Asthma; Carbachol; Caspase 8; Cell	2012
Inhibition of smooth muscle contraction by magnolol and honokiol in porcine trachea. Planta medica, 2003, Volume: 69, Issue:6 Topics: Animals; Asthma; Biphenyl Compounds; Bronchodilator Agents; Calcium; Carbachol; Dose-Response Relati	2003
New studies on aerosols. XVIII. Effects of atropine microaerosols on the airway resistance in man. Archives internationales de pharmacodynamie et de therapie, 1962, Sep-01, Volume: 139 Topics: Aerosols; Airway Resistance; Asthma; Atropine; Carbachol; Humans; Male; Pulmonary Emphysema; Respira	1962
[PHARMACOLOGICAL RESEARCH IN THE DIPHENYLCARBAMIDE THIOL ACID ESTER SERIES]. Archives internationales de pharmacodynamie et de therapie, 1964, Oct-01, Volume: 151 Topics: Acetylcholine; Anesthetics; Anesthetics, Local; Animals; Asthma; Atropine; Autonomic Nerve Block; Ba	1964
Effects of Ding-Chuan-Tang on bronchoconstriction and airway leucocyte infiltration in sensitized guinea pigs. Immunopharmacology and immunotoxicology, 2004, Volume: 26, Issue:1 Topics: Airway Resistance; Animals; Anti-Asthmatic Agents; Asthma; Bronchoalveolar Lavage Fluid; Bronchocons	2004
Murine model for non-IgE-mediated asthma. Inflammation, 2004, Volume: 28, Issue:3 Topics: Animals; Asthma; Carbachol; Dermatitis, Contact; Dinitrofluorobenzene; Disease Models, Animal; Dose-	2004
Therapeutic targeting of endothelial ligands for L-selectin (PNAd) in a sheep model of asthma. The American journal of pathology, 2005, Volume: 166, Issue:3 Topics: Animals; Antigens, Surface; Asthma; Bronchoalveolar Lavage; Carbachol; Carbohydrate Sulfotransferase	2005
Mechanisms of relaxant action of luteolin in isolated guinea pig trachea. Planta medica, 2005, Volume: 71, Issue:5 Topics: Animals; Asthma; Bronchodilator Agents; Carbachol; Dose-Response Relationship, Drug; Guinea Pigs; Hi	2005
The role of airway smooth muscle during an attack of asthma simulated in vitro. American journal of respiratory cell and molecular biology, 2005, Volume: 33, Issue:5 Topics: Adaptation, Physiological; Animals; Asthma; Bronchi; Carbachol; Constriction, Pathologic; Electric S	2005
Isoquercitrin from Argemone platyceras inhibits carbachol and leukotriene D4-induced contraction in guinea-pig airways. European journal of pharmacology, 2005, Oct-17, Volume: 522, Issue:1-3 Topics: Acetates; Animals; Anti-Asthmatic Agents; Anti-Inflammatory Agents, Non-Steroidal; Argemone; Asthma;	2005
Reduced airway hyperresponsiveness and tracheal responses during allergic asthma in mice lacking tyrosine kinase inducible T-cell kinase. The Journal of allergy and clinical immunology, 2006, Volume: 117, Issue:4 Topics: Acetylcholine; Adoptive Transfer; Animals; Asthma; Bronchial Hyperreactivity; Carbachol; CD4-Positiv	2006
Efficacy of IL-13 neutralization in a sheep model of experimental asthma. American journal of respiratory cell and molecular biology, 2007, Volume: 36, Issue:3 Topics: Amino Acid Sequence; Animals; Antibodies; Ascaris suum; Asthma; Base Sequence; Bronchial Hyperreacti	2007
Repeated allergen inhalation induces cytoskeletal remodeling in smooth muscle from rat bronchioles. American journal of respiratory cell and molecular biology, 2007, Volume: 36, Issue:6 Topics: Actins; Allergens; Animals; Antineoplastic Agents; Asthma; Bridged Bicyclo Compounds, Heterocyclic;	2007
Inhibitory effects of synthetic somatostatin receptor subtype 4 agonists on acute and chronic airway inflammation and hyperreactivity in the mouse. European journal of pharmacology, 2008, Jan-14, Volume: 578, Issue:2-3 Topics: Animals; Anti-Inflammatory Agents; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; B	2008
Parainfluenza 3 infection blocks the ability of a beta adrenergic receptor agonist to inhibit antigen-induced contraction of guinea pig isolated airway smooth muscle. The Journal of clinical investigation, 1981, Volume: 67, Issue:2 Topics: Adrenergic beta-Agonists; Animals; Asthma; Benzyl Alcohols; Benzyl Compounds; Bronchi; Carbachol; Fe	1981
[Suppressor activity changes in human T-lymphocytes as affected by adreno- and cholinotropic substances]. Zhurnal mikrobiologii, epidemiologii i immunobiologii, 1983, Issue:11 Topics: Asthma; Carbachol; Cells, Cultured; Concanavalin A; Humans; Lymphocyte Activation; Oxyfedrine; Propi	1983
Effect of Bordetella pertussis vaccination in mice and the isolated tracheal response to isoprenaline. Allergy, 1980, Volume: 35, Issue:4 Topics: Animals; Asthma; Bordetella pertussis; Carbachol; Histamine; Injections, Intraperitoneal; Isoprotere	1980
The relationship between bronchial hyperresponsiveness to methacholine and airway smooth muscle structure and reactivity. Respiration physiology, 1984, Volume: 58, Issue:2 Topics: Adult; Aged; Asthma; Bronchi; Carbachol; Female; Forced Expiratory Volume; Histamine; Humans; In Vit	1984
Bronchial challenges with ultrasonic mist, histamine and carbachol: a comparison in 87 asthmatic subjects. European journal of respiratory diseases. Supplement, 1983, Volume: 128 (Pt 2) Topics: Adult; Aerosols; Asthma; Bronchial Provocation Tests; Carbachol; Female; Histamine; Humans; Male; Ul	1983
Effects of ketotifen on cholinergic induced airway obstruction. European journal of respiratory diseases, 1983, Volume: 64, Issue:7 Topics: Adolescent; Adult; Airway Resistance; Asthma; Bronchi; Bronchial Provocation Tests; Carbachol; Doubl	1983
[Cause of bronchial hypersensitivity to histamine and carbachol]. Praxis und Klinik der Pneumologie, 1983, Volume: 37 Suppl 1 Topics: Airway Resistance; Asthma; Bronchial Provocation Tests; Carbachol; Histamine; Humans	1983
A comparison of in vivo and in vitro human airway reactivity to histamine. The American review of respiratory disease, 1984, Volume: 129, Issue:6 Topics: Aged; Asthma; Bronchi; Bronchial Provocation Tests; Carbachol; Cimetidine; Dose-Response Relationshi	1984
Influence of ketotifen on the airway responsiveness in asthmatics. The Journal of asthma : official journal of the Association for the Care of Asthma, 1984, Volume: 21, Issue:2 Topics: Adult; Airway Resistance; Asthma; Bronchi; Bronchial Provocation Tests; Carbachol; Dose-Response Rel	1984
[Bronchial provocation tests in children: their practical performance]. Allergologia et immunopathologia, 1981, Volume: Suppl 9 Topics: Acetylcholine; Allergens; Asthma; Bronchial Provocation Tests; Carbachol; Child; Dose-Response Relat	1981
Elastic properties of the lung in acute induced asthma. Journal of applied physiology: respiratory, environmental and exercise physiology, 1983, Volume: 54, Issue:1 Topics: Acute Disease; Adult; Asthma; Bronchial Spasm; Carbachol; Female; Functional Residual Capacity; Huma	1983
Airway response of asthmatics to carbachol and to deep inspiration. European journal of respiratory diseases, 1983, Volume: 64, Issue:2 Topics: Adult; Airway Resistance; Asthma; Bronchial Provocation Tests; Carbachol; Female; Forced Expiratory	1983
[Modifications of respiratory mechanics of asthmatics challenged with cholinergics and allergens]. Respiration; international review of thoracic diseases, 1983, Volume: 44, Issue:4 Topics: Adolescent; Adult; Allergens; Asthma; Biomechanical Phenomena; Bronchial Provocation Tests; Carbacho	1983
Measurement of airway hyperresponsiveness in man. European journal of respiratory diseases. Supplement, 1982, Volume: 117 Topics: Airway Resistance; Asthma; Bronchial Provocation Tests; Carbachol; Dose-Response Relationship, Drug;	1982
Effects of vaccination with Haemophilus influenzae on adrenoceptor function of tracheal and parenchymal strips. The Journal of pharmacology and experimental therapeutics, 1980, Volume: 215, Issue:3 Topics: Animals; Asthma; Bacterial Vaccines; Carbachol; Guinea Pigs; Haemophilus Infections; Haemophilus inf	1980
Factors influencing the bronchodilator effect of a deep inspiration in asthmatic patients with provoked bronchoconstriction. Thorax, 1982, Volume: 37, Issue:2 Topics: Adult; Airway Resistance; Asthma; Bronchial Provocation Tests; Carbachol; Constriction, Pathologic;	1982
Influence of the previous deep inspiration on the spirometric measurement of provoked bronchoconstriction in asthma. The American review of respiratory disease, 1981, Volume: 123, Issue:3 Topics: Asthma; Bronchial Provocation Tests; Bronchial Spasm; Carbachol; Female; Forced Expiratory Volume; F	1981
[Bronchial provocation tests in infants]. Allergologia et immunopathologia, 1981, Volume: Suppl 9 Topics: Age Factors; Asthma; Asthma, Exercise-Induced; Bronchial Provocation Tests; Bronchitis; Carbachol; H	1981
Bronchomotor effect of bronchoconstriction-induced deep inspirations in asthmatics. The American review of respiratory disease, 1980, Volume: 121, Issue:2 Topics: Adult; Airway Resistance; Albuterol; Asthma; Bronchi; Bronchial Provocation Tests; Carbachol; Constr	1980
Cholinergic nervous system and immediate hypersensitivity. II. An analysis of pupillary responses. The Journal of allergy and clinical immunology, 1980, Volume: 66, Issue:5 Topics: Adolescent; Adult; Aged; Asthma; Carbachol; Female; Humans; Hypersensitivity; Hypersensitivity, Imme	1980
Endothelin-1 receptor density, distribution, and function in human isolated asthmatic airways. American journal of respiratory and critical care medicine, 1995, Volume: 152, Issue:5 Pt 1 Topics: Adolescent; Adult; Asthma; Autoradiography; Bronchi; Carbachol; Dose-Response Relationship, Drug; En	1995
Allergen-induced airway inflammation and bronchial responsiveness in wild-type and interleukin-4-deficient mice. American journal of respiratory cell and molecular biology, 1995, Volume: 12, Issue:3 Topics: Allergens; Animals; Asthma; Bronchial Provocation Tests; Carbachol; Hypersensitivity; Immunoglobulin	1995
Stretch-induced myogenic responses of airways after histamine and carbachol. Clinical physiology (Oxford, England), 1994, Volume: 14, Issue:2 Topics: Animals; Asthma; Bronchoconstriction; Carbachol; Histamine; In Vitro Techniques; Male; Muscle, Smoot	1994
Specific approach on dose-response curves to inhaled carbachol assessed by the interruption technique in children. Pediatric research, 1993, Volume: 34, Issue:4 Topics: Administration, Inhalation; Adolescent; Asthma; Bronchial Provocation Tests; Carbachol; Child; Child	1993
Interfering factors to sensitivity and specificity of bronchial reactivity in children. Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology, 1993, Volume: 4, Issue:4 Topics: Adolescent; Asthma; Bronchi; Bronchial Hyperreactivity; Bronchial Provocation Tests; Carbachol; Chil	1993
Adenosine-induced bronchoconstriction in conscious hyperresponsive and sensitized guinea pigs. American journal of respiratory and critical care medicine, 1994, Volume: 149, Issue:2 Pt 1 Topics: Adenosine; Animals; Asthma; Bronchial Hyperreactivity; Bronchoconstriction; Carbachol; Guinea Pigs;	1994
Sensitization decreases relaxation in human isolated airways. The American review of respiratory disease, 1993, Volume: 148, Issue:1 Topics: Asthma; Benzopyrans; Bronchi; Bucladesine; Carbachol; Colforsin; Cromakalim; Dose-Response Relations	1993
Increased cholinergic antagonism underlies impaired beta-adrenergic response in ovalbumin-sensitized guinea pigs. Journal of applied physiology (Bethesda, Md. : 1985), 1993, Volume: 74, Issue:6 Topics: Animals; Asthma; Carbachol; Dinoprostone; Female; Guinea Pigs; Histamine; Immunization; In Vitro Tec	1993
[Bronchial provocation tests. Comparison of 2 inhalation methods]. Presse medicale (Paris, France : 1983), 1993, Sep-04, Volume: 22, Issue:25 Topics: Adult; Asthma; Bronchial Provocation Tests; Bronchospirometry; Carbachol; Dose-Response Relationship	1993
[Longitudinal study of bronchial hyperreactivity using the carbachol test with school children]. Pneumologie (Stuttgart, Germany), 1993, Volume: 47, Issue:2 Topics: Adolescent; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Carbachol; Child; Cohort	1993
Tryptase inhibitors block allergen-induced airway and inflammatory responses in allergic sheep. American journal of respiratory and critical care medicine, 1995, Volume: 152, Issue:6 Pt 1 Topics: Airway Resistance; Allergens; Animals; Antigens, Helminth; Ascaris suum; Asthma; Benzimidazoles; Bro	1995
LFA-1, and not Mac-1, is crucial for the development of hyperreactivity in a murine model of nonallergic asthma. American journal of respiratory and critical care medicine, 1996, Volume: 153, Issue:2 Topics: Animals; Antibodies, Monoclonal; Asthma; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Ca	1996
Plasma thrombospondin levels in sheep with allergic asthma. Chest, 1996, Volume: 109, Issue:6 Topics: Airway Resistance; Allergens; Animals; Ascaris; Asthma; Bronchial Provocation Tests; Carbachol; Cell	1996
LFA-1 and ICAM-1 are crucial for the induction of hyperreactivity in the mouse airways. Annals of the New York Academy of Sciences, 1996, Oct-31, Volume: 796 Topics: Animals; Antibodies, Monoclonal; Asthma; Bronchial Hyperreactivity; Carbachol; Disease Models, Anima	1996
Oscillatory pressure transients after flow interruption during bronchial challenge test in children. The European respiratory journal, 1997, Volume: 10, Issue:1 Topics: Acoustics; Adolescent; Air; Airway Obstruction; Airway Resistance; Albuterol; Asthma; Bronchial Prov	1997
Increased levels of protein kinase C in lymphocytes in asthma: possible mechanism of regulation. The European respiratory journal, 1997, Volume: 10, Issue:2 Topics: Adolescent; Adult; Aged; Asthma; Carbachol; Cell Fractionation; Cell Membrane; Cromolyn Sodium; Cyto	1997
Allergen challenge of passively sensitized human bronchi alters M2 and beta2 receptor function. American journal of respiratory and critical care medicine, 1997, Volume: 155, Issue:4 Topics: Adrenergic beta-Agonists; Adult; Aged; Albuterol; Allergens; Animals; Asthma; Bronchi; Bronchial Hyp	1997
Release of epithelium-derived PGE2 from canine trachea after antigen inhalation. The American journal of physiology, 1998, Volume: 274, Issue:2 Topics: Administration, Inhalation; Allergens; Animals; Antigens, Helminth; Ascaris suum; Asthma; Bronchial	1998
Antigen-induced responses in lung parenchymal strips during sinusoidal oscillation. Canadian journal of physiology and pharmacology, 1998, Volume: 76, Issue:2 Topics: Animals; Antigens; Asthma; Carbachol; Leukotriene D4; Lung; Muscarinic Agonists; Rats; Serotonin; Se	1998
Effects of LTD4 on human airway smooth muscle cell proliferation, matrix expression, and contraction In vitro: differential sensitivity to cysteinyl leukotriene receptor antagonists. American journal of respiratory cell and molecular biology, 1998, Volume: 19, Issue:3 Topics: Asthma; Carbachol; Cells, Cultured; Chromones; Dicarboxylic Acids; DNA Replication; Epidermal Growth	1998
Occupational asthma due to chromium. Respiration; international review of thoracic diseases, 1998, Volume: 65, Issue:5 Topics: Adult; Asthma; Bronchial Hyperreactivity; Carbachol; Chromium; Construction Materials; Forced Expira	1998
[Does idiopathic naso-sinusal polyposis exist in children?]. Archives de pediatrie : organe officiel de la Societe francaise de pediatrie, 1999, Volume: 6, Issue:4 Topics: Adolescent; Adult; Age Factors; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Bacterial	1999
Human isolated airway contraction: interaction between air pollutants and passive sensitization. American journal of respiratory and critical care medicine, 1999, Volume: 160, Issue:2 Topics: Acrolein; Adult; Air Pollutants; Airway Resistance; Asthma; Bronchi; Bronchial Hyperreactivity; Bron	1999
Passive sensitization of human airways increases responsiveness to leukotriene C4. The European respiratory journal, 1999, Volume: 14, Issue:2 Topics: Adult; Aged; Allergens; Asthma; Bronchial Provocation Tests; Bronchoconstriction; Carbachol; Dose-Re	1999
[Bronchial reactivity as factor of effectiveness of new antiasthmatic drugs]. Terapevticheskii arkhiv, 2000, Volume: 72, Issue:3 Topics: Administration, Inhalation; Airway Resistance; Anti-Asthmatic Agents; Asthma; Beclomethasone; Bronch	2000
Endogenous interleukin-10 suppresses allergen-induced airway inflammation and nonspecific airway responsiveness. Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 2000, Volume: 30, Issue:6 Topics: Allergens; Animals; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoalveolar	2000
A small-molecule, tight-binding inhibitor of the integrin alpha(4)beta(1) blocks antigen-induced airway responses and inflammation in experimental asthma in sheep. American journal of respiratory and critical care medicine, 2000, Volume: 162, Issue:2 Pt 1 Topics: Animals; Asthma; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Carbachol; Eosinophils; In	2000
Value of bronchial challenge in scuba diving candidates. The Journal of asthma : official journal of the Association for the Care of Asthma, 2000, Volume: 37, Issue:8 Topics: Adult; Airway Resistance; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Carbachol;	2000
Fluticasone inhibits the progression of allergen-induced structural airway changes. Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 2002, Volume: 32, Issue:6 Topics: Administration, Inhalation; Administration, Topical; Allergens; Androstadienes; Animals; Anti-Inflam	2002
Changes of airway smooth muscle in experimental asthma. Respiration physiology, 1978, Volume: 32, Issue:1 Topics: Animals; Asthma; Carbachol; Dose-Response Relationship, Drug; Guinea Pigs; Histamine; Male; Muscle C	1978
Bronchial asthma: the possible role of the chemical mediators of immediate hypersensitivity in the pathogenesis of subacute chronic disease. The American review of respiratory disease, 1975, Volume: 112, Issue:3 Topics: Acetylcholine; Adrenergic beta-Agonists; Anaphylaxis; Asthma; Autacoids; Blood Coagulation Factors;	1975
Airway response to carbachol in normal and asthmatic subjects: distinction between bronchial sensitivity and reactivity. The American review of respiratory disease, 1977, Volume: 115, Issue:6 Topics: Asthma; Bronchi; Bronchial Provocation Tests; Carbachol; Dose-Response Relationship, Drug; Female; H	1977
Subsensitivity of T lymphocytes to sympathomimetic and cholinergic stimulation in bronchial asthma. The Journal of allergy and clinical immunology, 1978, Volume: 61, Issue:4 Topics: Adult; Asthma; Carbachol; Female; Humans; Isoproterenol; Male; Middle Aged; Parasympathomimetics; Ro	1978
Differential airway reactivity to carbachol and physostigmine sulfate in rhesus monkeys with and without reagin-mediated respiratory responses. International archives of allergy and applied immunology, 1977, Volume: 53, Issue:4 Topics: Aerosols; Animals; Antigens; Ascaris; Asthma; Bronchi; Carbachol; Haplorhini; Macaca mulatta; Physos	1977
Indications for inhalation challenge. Study Group on Indications, Bronchoprovocation Committee, American Academy of Allergy. The Journal of allergy and clinical immunology, 1979, Volume: 64, Issue:6 pt 2 Topics: Antigens; Asthma; Bronchial Provocation Tests; Carbachol; Histamine; Humans; Methacholine Compounds	1979
Inhalation tests with cholinergic agents in asthmatic patients. Triangle; the Sandoz journal of medical science, 1978, Volume: 17, Issue:3-4 Topics: Asthma; Carbachol; Humans; Methods; Parasympathomimetics	1978
The effect of cholinergic and anticholinergic agents on the primate model of allergic asthma. The Journal of laboratory and clinical medicine, 1976, Volume: 87, Issue:1 Topics: Airway Resistance; Animals; Antigens; Asthma; Atropine; Carbachol; Disease Models, Animal; Female; H	1976
A comparison of immunologic asthma to two types of cholinergic respiratory responses in the rhesus monkey. The Journal of laboratory and clinical medicine, 1976, Volume: 88, Issue:6 Topics: Acetylcholine; Aerosols; Airway Resistance; Animals; Antigens; Ascaris; Asthma; Atropine; Carbachol;	1976
Reassessment of the significance of delayed blanch phenomenon and serum tigE levels in atopic disorders. Annals of allergy, 1977, Volume: 38, Issue:4 Topics: Asthma; Carbachol; Dermatitis, Atopic; Humans; Hypersensitivity, Immediate; Immunoglobulin E; Intrad	1977
A new simple spirometric index for use with bronchial provocation tests. Annals of allergy, 1977, Volume: 38, Issue:5 Topics: Adolescent; Adult; Aged; Airway Obstruction; Asthma; Bronchi; Carbachol; Child; Female; Forced Expir	1977
Effect of maximal respiratory manoeuvres on bronchial sensitivity of asthmatic patients as compared to normal people. British medical journal, 1975, Jan-18, Volume: 1, Issue:5950 Topics: Adolescent; Adult; Aerosols; Airway Resistance; Asthma; Bronchi; Carbachol; Child, Preschool; Dose-R	1975
Clinical potency of calcium channel blockers in asthma may be related to their inhibition of receptor-mediated phasic responses in vitro. Life sciences, 1992, Volume: 51, Issue:26 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e	1992
Relationship between spontaneous dyspnoea and lability of airway obstruction in asthma. Clinical science (London, England : 1979), 1992, Volume: 82, Issue:6 Topics: Adolescent; Adult; Aged; Airway Obstruction; Albuterol; Asthma; Bronchi; Carbachol; Dyspnea; Female;	1992
[Reactivity of the bronchi as a function of their initial state in children with asthma]. Pneumonologia i alergologia polska, 1991, Volume: 59, Issue:11-12 Topics: Administration, Inhalation; Adolescent; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tes	1991
[Standardization of the carbachol inhalation provocation tests using a reservoir method]. Pneumologie (Stuttgart, Germany), 1991, Volume: 45 Suppl 2 Topics: Adult; Asthma; Bronchial Provocation Tests; Carbachol; Dose-Response Relationship, Drug; Female; Hum	1991
[Carbachol inhalation provocation test using a reservoir method. 4-step test for the assessment of bronchial hyperreactivity]. Pneumologie (Stuttgart, Germany), 1991, Volume: 45 Suppl 2 Topics: Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Carbachol; Dose-Response Relationshi	1991
Epithelium-derived inhibitory factor in human bronchus. European journal of pharmacology, 1990, Oct-23, Volume: 187, Issue:3 Topics: Animals; Asthma; Biological Factors; Bronchi; Carbachol; Histamine; Humans; In Vitro Techniques; Ind	1990
Allergy and asthma. Lung, 1990, Volume: 168 Suppl Topics: Adolescent; Allergens; Asthma; Bronchial Provocation Tests; Carbachol; Child; Female; Forced Expirat	1990
Effect of sensitization and aerosol antigen challenge in guinea-pigs--studies of airway receptor function and characteristics. Pulmonary pharmacology, 1990, Volume: 3, Issue:3 Topics: Aerosols; Animals; Antigens; Asthma; Carbachol; Guinea Pigs; Immunization; In Vitro Techniques; Isop	1990
Correspondence between forced oscillation and body plethysmography during bronchoprovocation with carbachol in children. Pediatric pulmonology, 1990, Volume: 8, Issue:4 Topics: Administration, Inhalation; Adolescent; Airway Resistance; Asthma; Bronchial Provocation Tests; Carb	1990
[Fading of the provocation effect following inhaled provocation with carbachol]. Pneumologie (Stuttgart, Germany), 1990, Volume: 44 Suppl 1 Topics: Adult; Airway Resistance; Asthma; Bronchial Provocation Tests; Carbachol; Female; Forced Expiratory	1990
[Effect of histamine on bronchial hyperreactivity in sarcoidosis and other lung diseases]. Pneumologie (Stuttgart, Germany), 1990, Volume: 44 Suppl 1 Topics: Acetylcholine; Asthma; Bronchial Provocation Tests; Carbachol; Histamine; Humans; Lung Diseases; Res	1990
Alpha 1-adrenoceptor function and autoradiographic distribution in human asthmatic lung. British journal of pharmacology, 1989, Volume: 97, Issue:3 Topics: Adult; Asthma; Autoradiography; Bronchi; Carbachol; Humans; In Vitro Techniques; Iodine Radioisotope	1989
[Effect of air pollutant burden on healthy children and children with lung diseases in southern Ticino]. Schweizerische medizinische Wochenschrift, 1989, Dec-23, Volume: 119, Issue:51 Topics: Adolescent; Air Pollutants; Allergens; Asthma; Bronchial Provocation Tests; Carbachol; Child; Female	1989
Atropine does not inhibit late asthmatic responses induced by toluene-diisocyanate in sensitized subjects. The American review of respiratory disease, 1987, Volume: 136, Issue:5 Topics: Administration, Inhalation; Adult; Airway Resistance; Asthma; Atropine; Carbachol; Cyanates; Female;	1987
In vitro responsiveness of human asthmatic bronchus to carbachol, histamine, beta-adrenoceptor agonists and theophylline. British journal of clinical pharmacology, 1986, Volume: 22, Issue:6 Topics: Adolescent; Adrenergic beta-Agonists; Adult; Aged; Airway Resistance; Asthma; Bronchi; Carbachol; Ch	1986
Chronic persistent cough. Experience in diagnosis and outcome using an anatomic diagnostic protocol. Chest, 1989, Volume: 95, Issue:4 Topics: Adult; Aged; Asthma; Bronchial Provocation Tests; Bronchitis; Carbachol; Chronic Disease; Clinical P	1989
Influence of the epithelium on responsiveness of guinea-pig isolated trachea to contractile and relaxant agonists. British journal of pharmacology, 1986, Volume: 87, Issue:1 Topics: Acetylcholine; Animals; Asthma; Autoradiography; Carbachol; Cimetidine; Colforsin; Dose-Response Rel	1986
[Excitability of bronchial receptors in infectious allergic bronchial asthma]. Klinicheskaia meditsina, 1986, Volume: 64, Issue:8 Topics: Adolescent; Adult; Asthma; Bronchi; Bronchial Provocation Tests; Carbachol; Cold Temperature; Female	1986
A role for inflammatory mediators in airway hyper-responsiveness. Progress in clinical and biological research, 1988, Volume: 263 Topics: Animals; Asthma; Bronchi; Bronchial Spasm; Carbachol; Dinoprost; Histamine; Muscle, Smooth; Prostagl	1988
[Inhalant propranolol provocation test: a new method for the differentiation between healthy and asthmatic subjects]. Praxis und Klinik der Pneumologie, 1988, Volume: 42 Suppl 1 Topics: Adult; Aerosols; Asthma; Bronchial Provocation Tests; Carbachol; Female; Humans; Male; Propranolol;	1988
[Persistence of nonspecific bronchial hyperreactivity in children with non-IgE dependent bronchial asthma: pharmacologic study with the Carbachol test]. Anales espanoles de pediatria, 1988, Volume: 29, Issue:5 Topics: Adolescent; Asthma; Bronchi; Bronchial Provocation Tests; Carbachol; Child; Child, Preschool; Female	1988
Bronchial reactivity in diabetic patients. Relationship to duration of diabetes and degree of glycemic control. American journal of diseases of children (1960), 1988, Volume: 142, Issue:7 Topics: Adolescent; Asthma; Bronchial Provocation Tests; Carbachol; Child; Diabetes Mellitus, Type 1; Female	1988
[Influenza vaccination and asthma]. Allergie et immunologie, 1987, Volume: 19, Issue:1 Topics: Adult; Aged; Aged, 80 and over; Asthma; Bronchial Provocation Tests; Carbachol; Female; Humans; Infl	1987
[Bronchial hyperreactivity. Methods of detection with pharmacologic substances]. Praxis und Klinik der Pneumologie, 1986, Volume: 40, Issue:5 Topics: Acetylcholine; Airway Obstruction; Asthma; Bronchial Provocation Tests; Carbachol; Histamine; Humans	1986
Asthma without airway hyperresponsiveness to carbachol. European journal of respiratory diseases, 1987, Volume: 70, Issue:4 Topics: Adolescent; Adult; Airway Resistance; Asthma; Bronchial Provocation Tests; Carbachol; Dose-Response	1987
Different bronchoconstrictor effects of carbachol boluses inhaled near residual volume or total lung capacity. Respiration; international review of thoracic diseases, 1987, Volume: 51, Issue:2 Topics: Adult; Aerosols; Airway Resistance; Asthma; Bronchial Provocation Tests; Carbachol; Dose-Response Re	1987
Airway responses in vitro following C5a des Arg-induced hyper-responsiveness in vivo in rabbits. Clinical and experimental pharmacology & physiology, 1987, Volume: 14, Issue:1 Topics: Airway Resistance; Animals; Asthma; Carbachol; Complement C5; Complement C5a, des-Arginine; Female;	1987
Pupillary responses and airway reactivity in asthma. The Journal of allergy and clinical immunology, 1986, Volume: 77, Issue:5 Topics: Adolescent; Adult; Airway Obstruction; Asthma; Bronchi; Carbachol; Female; Humans; Hypersensitivity,	1986
Genetic factors in nonspecific bronchial hyperreactivity. An epidemiologic study. American journal of diseases of children (1960), 1987, Volume: 141, Issue:3 Topics: Adolescent; Adult; Aerosols; Asthma; Bronchial Provocation Tests; Carbachol; Child; Dose-Response Re	1987
Influence of aeroallergens on bronchial reactivity in children sensitized to grass pollens. Annals of allergy, 1986, Volume: 56, Issue:2 Topics: Air Pollution; Asthma; Bronchi; Carbachol; Child; Female; Humans; Male; Pollen	1986
Genetic factors in non-specific bronchial reactivity in rats. European journal of respiratory diseases, 1985, Volume: 66, Issue:2 Topics: Animals; Asthma; Bronchial Provocation Tests; Bronchial Spasm; Carbachol; Genes, Recessive; Male; Pr	1985
[Bronchial reactions to carbachol inhalation in patients with a suspected diagnosis of cough due to asthma]. Schweizerische medizinische Wochenschrift, 1985, May-04, Volume: 115, Issue:18 Topics: Adult; Asthma; Bronchi; Bronchial Provocation Tests; Carbachol; Cough; Female; Forced Expiratory Vol	1985
The effect of an alpha-adrenergic receptor blocking drug on histamine sensitivity in bronchial asthma. British journal of diseases of the chest, 1972, Volume: 66, Issue:2 Topics: Adrenergic alpha-Antagonists; Adult; Aged; Asthma; Blood Pressure; Carbachol; Female; Histamine Anta	1972
Role of counter-conditioning in the treatment of asthma. The Journal of asthma research, 1973, Volume: 11, Issue:2 Topics: Adolescent; Aerosols; Allergens; Asthma; Behavior Therapy; Carbachol; Child; Evaluation Studies as T	1973
Measurement of airway variation and bronchial reactivity in normal and asthmatic subjects. The American review of respiratory disease, 1967, Volume: 96, Issue:2 Topics: Administration, Inhalation; Adult; Airway Resistance; Asthma; Carbachol; Female; Humans; Isoproteren	1967
5,5-diphenyl-2-(2'-piperidinoethyl)-1,3-dioxolane-4-one a new drug with potent spasmolytic activity. Pharmacology, 1970, Volume: 3, Issue:4 Topics: Acetylcholine; Animals; Asthma; Atropine; Barium; Blood Pressure; Blood Vessels; Carbachol; Cats; Ch	1970
[Long-term observation of the bronchial resistance and sensitivity to bronchoconstrictors in asthma patients]. Schweizerische medizinische Wochenschrift, 1968, Jun-01, Volume: 98, Issue:22 Topics: Adult; Asthma; Carbachol; Drug Tolerance; Female; Humans; Male; Respiratory Physiological Phenomena;	1968

carbachol and Asthma

Research Excerpts

Research

Studies (156)

Authors

Clinical Trials (1)

Trial Overview

Reviews

Trials

Other Studies

Authors	Studies
Hamid, I	1
Janbaz, KH	1
Iqbal, R	1
Akhtar, MF	1
Saleem, A	1
Ali, S	1
Sharif, A	1
Akhtar, B	1
Javaid, Z	1
Sohail, K	1
Xu, S	1
Karmacharya, N	1
Woo, J	1
Cao, G	2
Guo, C	1
Gow, A	1
Panettieri, RA	5
Jude, JA	1
Parikh, V	1
Scala, J	1
Patel, R	1
Corbi, C	1
Lo, D	1
Bochkov, YA	1
Kennedy, JL	1
Kurten, RC	1
Liggett, SB	1
Gern, JE	1
Koziol-White, CJ	1
Lee, MK	1
Lim, KH	1
Millns, P	1
Mohankumar, SK	1
Ng, ST	1
Tan, CS	1
Then, SM	1
Mbaki, Y	1
Ting, KN	1
Orfanos, S	1
Jude, J	1
Deeney, BT	1
Rastogi, D	1
van Zee, M	1
Pushkarsky, I	1
Munoz, HE	1
Damoiseaux, R	1
Di Carlo, D	1
Kai, Y	2
Motegi, M	2
Suzuki, Y	2
Takeuchi, H	2
Harada, Y	2
Sato, F	1
Chiba, Y	2
Kamei, J	2
Sakai, H	2
Lacerda Ribeiro, MT	1
Paes Porto, HK	1
de Oliveira, DF	1
da Silva Castro, PF	1
Rocha, ML	1
Kon, R	1
Ikarashi, N	1
Van Der Velden, J	1
Sum, G	1
Barker, D	1
Koumoundouros, E	1
Barcham, G	1
Wulff, H	1
Castle, N	1
Bradding, P	1
Snibson, K	1
Costa, L	1
Roth, M	1
Miglino, N	1
Keglowich, L	1
Zhong, J	1
Lardinois, D	1
Tamm, M	1
Borger, P	1
Shareef, H	1
Rizwani, GH	1
Mandukhail, SR	1
Watanabe, N	1
Gilani, AH	2
Bozkurt, TE	1
Kaya, Y	1
Durlu-Kandilci, NT	1
Onder, S	1
Sahin-Erdemli, I	1
Moura, CTM	1
Batista-Lima, FJ	1
Brito, TS	1
Silva, AAV	1
Ferreira, LC	1
Roque, CR	1
Aragão, KS	1
Havt, A	1
Fonseca, FN	1
Leal, LKAM	1
Magalhães, PJC	1
Chen, H	1
Jacobson, BA	2
Mason, L	1
Wolf, SF	1
Bowman, MR	1
Fogli, S	1
Pellegrini, S	1
Adinolfi, B	1
Mariotti, V	1
Melissari, E	1
Betti, L	1
Fabbrini, L	1
Giannaccini, G	1
Lucacchini, A	1
Bardelli, C	1
Stefanelli, F	1
Brunelleschi, S	1
Breschi, MC	1
Leemans, J	1
Kirschvink, N	1
Bernaerts, F	1
Clercx, C	1
Snaps, F	1
Billen, F	1
Gustin, P	1
Shah, AJ	1
Damera, G	2
Druey, KM	1
Cooper, PR	1
Krymskaya, VP	1
Soberman, RJ	1
Amrani, Y	1
Hoshi, T	2
Brightling, CE	1
Ahmed, T	1
Smith, G	1
Vlahov, I	1
Abraham, WM	6
West, AR	1
Needi, ET	1
Mitchell, HW	1
McFawn, PK	1
Noble, PB	1
Banerjee, A	1
Trivedi, CM	1
Jiang, M	1
Jester, W	1
Epstein, JA	1
Pascoe, C	1
Jiao, Y	1
Seow, CY	2
Paré, PD	3
Bossé, Y	1
Olsen, PC	1
Coelho, LP	1
da Costa, JC	1
Cordeiro, RS	1
Silva, PM	1
Martins, MA	1
Zhao, W	1
Rouatbi, S	1
Tabka, Z	1
Guénard, H	1
Ko, CH	1
Chen, HH	1
Lin, YR	1
Chan, MH	1
DAUTREBANDE, L	1
LOVEJOY, FW	1
McCREDIE, RM	1
WIRTH, W	1
GOESSWALD, R	1
RISSE, KH	1
HOERLEIN, U	1
Kao, ST	1
Chang, CH	1
Chen, YS	1
Chiang, SY	1
Lin, JG	1
van der Kleij, HP	1
Kraneveld, AD	1
van Houwelingen, AH	1
Kool, M	1
Weitenberg, AC	1
Redegeld, FA	3
Nijkamp, FP	5
Rosen, SD	1
Tsay, D	1
Singer, MS	1
Hemmerich, S	1
Ko, WC	1
Shih, CM	1
Leu, IJ	1
Chen, TT	1
Chang, JP	1
McParland, BE	1
Tait, RR	1
Fernandez, J	1
Reyes, R	1
Ponce, H	1
Oropeza, M	1
Vancalsteren, MR	1
Jankowski, C	1
Campos, MG	1
Ferrara, TJ	1
Mueller, C	1
Sahu, N	1
Ben-Jebria, A	1
August, A	1
Kasaian, MT	1
Donaldson, DD	1
Tchistiakova, L	1
Marquette, K	1
Tan, XY	1
Ahmed, A	3
Widom, A	1
Cook, TA	1
Xu, X	1
Barry, AB	1
Goldman, SJ	1
McVicker, CG	1
Leung, SY	1
Kanabar, V	1
Moir, LM	1
Mahn, K	1
Chung, KF	1
Hirst, SJ	1
Elekes, K	1
Helyes, Z	1
Kereskai, L	1
Sándor, K	1
Pintér, E	1
Pozsgai, G	1
Tékus, V	1
Bánvölgyi, A	1
Németh, J	1
Szuts, T	1
Kéri, G	1
Szolcsányi, J	1
Buckner, CK	1
Clayton, DE	1
Ain-Shoka, AA	1
Busse, WW	2
Dick, EC	1
Shult, P	1
Schreurs, AJ	2
Salmasi, ZhM	1
Gol'dshteĭn, MM	1
Poriadin, GV	1
Bartell, TE	1
Armour, CL	5
Black, JL	5
Berend, N	2
Woolcock, AJ	1
Fabbri, LM	2
Mapp, CE	1
Hendrick, DJ	1
Rosati, G	1
Mormile, F	1
Ciappi, G	1
Utell, MJ	2
Morrow, PE	2
Speers, DM	2
Darling, J	1
Hyde, RW	2
Matthys, H	5
Klein, G	5
Köhler, D	1
Schulz, N	1
Schiess, W	2
Hartmann, V	2
Jörres, R	2
Magnussen, H	3
Lazar, NM	1
Schellenberg, RR	1
Taylor, SM	1
Chan, N	1
Hogg, JC	1
Dorow, P	1
Liebhart, E	1
Rufin, P	2
Benoist, MR	2
Vonlanthen, MC	2
Jean, R	2
Rodenstein, D	1
Stănescu, DC	1
Beaupre, A	3
Badier, M	6
Delpierre, S	4
Orehek, J	13
Grimaud, C	6
Clauzel, AM	1
Friemel, F	1
Garcelon, M	1
Calvayrac, P	1
Cannet, G	1
Michel, FB	1
Terpstra, GK	1
Raaijmakers, JA	1
Nicoli, MM	1
Charpin, D	1
Velardocchio, JM	1
Smith, LJ	1
Shelhamer, JH	1
Kaliner, M	1
Goldie, RG	5
Henry, PJ	2
Knott, PG	1
Self, GJ	1
Luttmann, MA	2
Hay, DW	2
Müller, S	1
Herceg, R	1
Brusselle, G	1
Kips, J	1
Joos, G	1
Bluethmann, H	1
Pauwels, R	2
Thulesius, O	1
Mustafa, S	1
Sommer, CW	2
Frey, U	2
Schönli, MH	1
Kraemer, R	5
Gschwend-Eigenmann, S	2
Schöni, MH	2
Stadler, BM	1
Thorne, JR	1
Broadley, KJ	1
Claussen, M	1
Sill, V	1
Villanove, X	1
Marthan, R	2
Tunon de Lara, JM	1
Johnson, PR	3
Savineau, JP	2
McKay, KO	1
Alouan, LA	1
Wills-Karp, M	1
Gilmour, MI	1
Guillot, C	4
Vanuxem, P	1
Forster, J	1
Hendel-Kramer, A	1
Weis, K	1
Kühr, J	1
Sousa, AR	1
Poston, RN	1
Lane, SJ	1
Nakhosteen, JA	1
Lee, TH	1
Clark, JM	1
Fishman, CE	1
Forteza, R	1
Cortes, A	1
Warne, RL	1
Moore, WR	1
Tanaka, RD	1
Bloemen, PG	2
Buckley, TL	2
van den Tweel, MC	2
Henricks, PA	2
Koster, AS	2
Bansal, SK	1
Jha, A	1
Jaiswal, AS	1
Chhabra, SK	1
Song, P	1
Milanese, M	1
Crimi, E	1
Rehder, K	1
Brusasco, V	1
Fontanari, P	1
Zattara-Hartmann, MC	1
Burnet, H	1
Jammes, Y	1
McGrogan, I	1
Janssen, LJ	1
Wattie, J	1
O'Byrne, PM	1
Daniel, EE	1
Nagase, T	1
Ludwig, MS	1
Dubus, JC	2
Oddoze, C	1
Bruguerolle, B	1
Tan, EM	1
Ciocca, V	1
Leonard, TB	1
Leroyer, C	1
Dewitte, JD	1
Bassanets, A	1
Boutoux, M	1
Daniel, C	1
Clavier, J	1
Pialoux, R	1
Coffinet, L	1
Derelle, J	1
Jankowski, R	1
Roux, E	1
Hyvelin, JM	1
Schmidt, D	1
Ruehlmann, E	1
Branscheid, D	1
Rabe, KF	1
Pol'ner, SA	1
Chervinskaia, TA	1
Tournoy, KG	1
Kips, JC	2
Pauwels, RA	2
Gill, A	1
Sielczak, MW	1
Lauredo, IT	1
Botinnikova, Y	1
Lin, KC	1
Pepinsky, B	1
Leone, DR	1
Lobb, RR	1
Adams, SP	1
Fornaris, E	1
Jacquin, M	1
Giebelhaus, V	1
von Fallois, J	1
Vanacker, NJ	1
Palmans, E	1
Charpin, J	7
Souhrada, JF	1
Austen, KF	1
Orange, RP	1
Gayrard, P	4
Smith, AP	1
Lang, P	1
Goel, Z	1
Grieco, MH	1
Miller, MM	2
Patterson, R	3
Swinburne, AJ	1
Gibb, FR	1
Rosenthal, RR	1
Chai, H	1
Mathison, DA	1
Spector, SL	1
Townley, RG	1
Harris, KE	2
Kanwar, AJ	1
Pasricha, JS	1
Malaviya, AM	1
Massari, JP	1
Ben-Harari, RR	1
Stenner, M	1
Sutin, KM	1
Peiffer, C	1
Toumi, M	1
Razzouk, H	1
Marsac, J	1
Lockhart, A	1
Kulus, M	1
Milanowski, A	1
Zawadzka, A	1
Czarnocka, E	1
Wagner-Heck, M	2
Zinn, GC	1
Zinn, CG	1
Fernandes, LB	1
Preuss, JM	1
Paterson, JW	4
Urbanek, R	1
Whicker, SD	1
Compton, MR	1
Seale, JP	1
Buhr, W	1
Berdel, D	1
Làndsér, FJ	1
Schlegel, J	1
Schulz, V	1
Velcovsky, HG	1
Discher, T	1
Spina, D	3
Rigby, PJ	2
D'Apuzzo, V	1
Paggiaro, P	1
Bacci, E	1
Talini, D	1
Dente, FL	1
Rossi, O	1
Pulerá, N	1
Giuntini, C	1
Lulich, KM	1
Poe, RH	1
Harder, RV	1
Israel, RH	1
Kallay, MC	1
Carnimeo, N	1
Resta, O	1
Foschino Barbaro, MP	1
Picca, V	1
D'Amore, ME	1
Garofalo, G	1
Carnimeo, R	1
Papadimitriou, JM	1
Self, HM	1
Prokopishina, LV	1
Sennhauser, F	1
Reinhardt, M	1
Rühle, KH	1
Vecora Navarro, MD	1
Oliván Gonzalvo, G	1
Colás Sanz, C	1
Escuer Alarma, JL	1
Duce Gracía, F	1
Cockcroft, DW	1
Villa, MP	1
Cacciari, E	1
Bernardi, F	1
Cicognani, A	1
Salardi, S	1
Zapulla, F	1
Miguères, J	1
Sallerin, F	1
Zayani, R	1
Escamilla, R	1
Snashall, PD	1
Giffon, E	1
Vervloet, D	2
Arnaud, A	1
Vincenc, KS	1
Ward, H	1
Davis, PB	1
Longo, G	1
Strinati, R	1
Poli, F	1
Fumi, F	1
Crivelli, M	2
Wahlländer, A	1
Jost, G	1
Preisig, R	1
Bachofen, H	2
Barbato, A	1
Pisetta, F	1
Norbiato, M	1
Ragusa, A	1
Mesirca, P	1
Pesenti, P	1
Marcer, G	1
Van Der Straeten, M	1
Weyne, J	1
Bazin, H	1
Zeller, C	1
Gaddie, J	1
Legge, JS	1
Petrie, G	1
Palmer, KN	1
Khan, AU	2
Bonk, C	2
Gordon, Y	1
Staerk, M	1
Graham, WG	1
Heim, E	2
Constantine, HP	1
Mörsdorf, K	1
Wengenroth, H	1
Constantine, H	1
Graham, W	1