Page last updated: 2024-11-07

carbachol and Anesthesia

carbachol has been researched along with Anesthesia in 42 studies

Carbachol: A slowly hydrolyzed CHOLINERGIC AGONIST that acts at both MUSCARINIC RECEPTORS and NICOTINIC RECEPTORS.

Anesthesia: A state characterized by loss of feeling or sensation. This depression of nerve function is usually the result of pharmacologic action and is induced to allow performance of surgery or other painful procedures.

Research Excerpts

ExcerptRelevanceReference
"Pretreatment with atropine reversed MAC reduction by carbachol, and both atropine and mecamylamine shortened recovery time under carbachol."5.31Effects of cholinomimetic injection into the brain stem reticular formation on halothane anesthesia and antinociception in rats. ( Dohi, S; Ishizawa, Y; Ma, HC; Shimonaka, H, 2000)
"Aclidinium bromide is a novel potent, long-acting inhaled muscarinic antagonist in development for the treatment of chronic obstructive pulmonary disease."1.35Characterization of aclidinium bromide, a novel inhaled muscarinic antagonist, with long duration of action and a favorable pharmacological profile. ( Beleta, J; Carcasona, C; Carreño, C; Cortijo, J; Doménech, T; Gavaldà, A; Gras, J; Llenas, J; Miralpeix, M; Morcillo, E; Otal, R; Ramos, I; Reyes, B; Ryder, H; Vilella, D; Viñals, M, 2009)
"A novel class of biphenyl analogues containing a benzoic acid moiety based on lead compound 8i have been identified as potent and selective human beta 3 adrenergic receptor (beta 3-AR) agonists with good oral bioavailability and long plasma half-life."1.35Discovery of a novel series of biphenyl benzoic acid derivatives as potent and selective human beta3-adrenergic receptor agonists with good oral bioavailability. Part I. ( Hamada, K; Hamashima, H; Hattori, K; Imamura, E; Imanishi, M; Ishikawa, H; Itou, S; Matsui, S; Matsumura, Y; Nakajima, Y; Nakano, K; Sakurai, M; Takamura, F; Tomishima, Y; Ueshima, K; Unami, N; Washizuka, K; Yamamoto, N; Yamamoto, T, 2008)
"The carbachol-induced increase in intravesical pressure and salivation was simultaneously recorded before and after increasing doses of test drugs administered intravenously."1.34Comparative in vivo uroselectivity profiles of anticholinergics, tested in a novel anesthetized rabbit model. ( Chugh, A; Gupta, JB; Hegde, LG; Kumar, N; Meru, AV; Naruganahalli, KS; Ray, A; Sinha, S, 2007)
"Solifenacin succinate is a novel muscarinic receptor antagonist used for the treatment of overactive bladder (OAB)."1.34Effects of intravenously and orally administered solifenacin succinate (YM905) on carbachol-induced intravesical pressure elevation and salivary secretion in mice. ( Noguchi, Y; Ohtake, A; Okutsu, H; Sasamata, M; Sato, S; Suzuki, M, 2007)
"The total number of ventricular ectopic beats was markedly augmented with fasudil at 0."1.33Effects of fasudil, a Rho-kinase inhibitor, on myocardial preconditioning in anesthetized rats. ( Babül, A; Celik, A; Demiryürek, AT; Demiryürek, S; Kara, AF; Tarakçioglu, M, 2005)
"Trimetazidine is a widely used anti-ischemic agent, but its effect on myocardial preconditioning in anesthetized animals has not been investigated."1.32Effects of trimetazidine on myocardial preconditioning in anesthetized rats. ( Celik, A; Demiryürek, AT; Demiryürek, S; Kara, AF; Tarakçioğlu, M, 2004)
"Pretreatment with atropine reversed MAC reduction by carbachol, and both atropine and mecamylamine shortened recovery time under carbachol."1.31Effects of cholinomimetic injection into the brain stem reticular formation on halothane anesthesia and antinociception in rats. ( Dohi, S; Ishizawa, Y; Ma, HC; Shimonaka, H, 2000)
"Both carbachol EEG effects were blocked by intraseptal infusion of the antimuscarinic agent, atropine."1.29Hippocampal EEG responses induced by carbachol and atropine infusions into the septum and the hippocampus in the urethane-anaesthetized rat. ( Ayadi, K; Breton, P; Monmaur, P, 1993)

Research

Studies (42)

TimeframeStudies, this research(%)All Research%
pre-199012 (28.57)18.7374
1990's14 (33.33)18.2507
2000's11 (26.19)29.6817
2010's4 (9.52)24.3611
2020's1 (2.38)2.80

Authors

AuthorsStudies
Pal, D1
Li, D1
Dean, JG1
Brito, MA1
Liu, T1
Fryzel, AM1
Hudetz, AG1
Mashour, GA1
Bocian, R2
Kłos-Wojtczak, P1
Caban, B2
Kowalczyk, T2
Kaźmierska, P1
Konopacki, J2
Gavaldà, A1
Miralpeix, M1
Ramos, I1
Otal, R1
Carreño, C1
Viñals, M1
Doménech, T1
Carcasona, C1
Reyes, B1
Vilella, D1
Gras, J1
Cortijo, J1
Morcillo, E1
Llenas, J1
Ryder, H1
Beleta, J1
Villetti, G1
Pastore, F1
Bergamaschi, M1
Bassani, F1
Bolzoni, PT1
Battipaglia, L1
Amari, G1
Rizzi, A2
Delcanale, M1
Volta, R1
Cenacchi, V1
Cacciani, F1
Zaniboni, M1
Berti, F1
Rossoni, G1
Harrison, S1
Petrillo, P1
Santoro, E1
Scudellaro, R1
Mannini, F1
Geppetti, PA1
Razzetti, R1
Patacchini, R1
Civelli, M1
Zhou, J1
Luan, GD1
Ren, LM1
Wu, ZG1
Wang, X1
Zhao, Y1
Kara, AF2
Demiryürek, S2
Celik, A2
Tarakçioğlu, M2
Demiryürek, AT2
Lai, YL1
Lee, KC1
Kuo, PH1
Aguilar, JR1
Castro-Alamancos, MA1
Babül, A1
Masri, R1
Trageser, JC1
Bezdudnaya, T1
Li, Y1
Keller, A1
Naruganahalli, KS1
Sinha, S1
Hegde, LG1
Meru, AV1
Chugh, A1
Kumar, N1
Gupta, JB1
Ray, A1
Okutsu, H1
Noguchi, Y1
Ohtake, A1
Suzuki, M1
Sato, S1
Sasamata, M1
Imanishi, M1
Tomishima, Y1
Itou, S1
Hamashima, H1
Nakajima, Y1
Washizuka, K1
Sakurai, M1
Matsui, S1
Imamura, E1
Ueshima, K1
Yamamoto, T1
Yamamoto, N1
Ishikawa, H1
Nakano, K1
Unami, N1
Hamada, K1
Matsumura, Y1
Takamura, F1
Hattori, K1
Leszkowicz, E1
Kuśmierczak, M1
Matulewicz, P1
Trojniar, W1
Inoue, A1
Takahashi, H1
Okajima, H1
Yoneda, S1
Sasaki, S1
Takeda, K1
Yoshimura, M1
Nakagawa, M1
Ijichi, H1
Poole, S1
Engler, H1
Beck, H1
Szelenyi, I1
Wasserman, MA1
Ducharme, DW1
Wendling, MG1
Griffin, RL1
Degraaf, GL1
Barbelivien, A1
MacKenzie, ET1
Dauphin, F1
Ozkutlu, U1
Coşkun, T1
Onat, F1
Yeğen, BC1
Oktay, S1
Ally, A1
Hara, Y1
Murayama, S1
Finney, MJ1
Forsberg, KI1
Monmaur, P1
Ayadi, K1
Breton, P1
Kohlmeier, KA1
López-Rodríguez, F1
Liu, RH1
Morales, FR1
Chase, MH1
Cellier, E1
Fayolle, C1
Hipskind, PA1
Iyengar, S1
Couture, R2
Bigoni, R1
Giuliani, S1
Calo', G1
Guerrini, R1
Salvadori, S1
Regoli, D1
Maggi, CA1
Horner, RL1
Kubin, L1
Dutschmann, M1
Herbert, H1
Ishizawa, Y1
Ma, HC1
Dohi, S1
Shimonaka, H1
Jennewein, HM1
Hasséssian, H1
Prat, A1
Marks, GA1
Roffwarg, HP1
Roquebert, J1
Alaoui, K1
Morán Benito, A1
Esplugues, JV1
Ramos, EG1
Gil, L1
Esplugues, J1
Ogawa, N1
Ono, H1
Puurunen, J1
Huttunen, P1
Aggarwal, PK1
Kumar, L1
Garg, SK1
Mathur, VS1
DiMicco, JA1
Abshire, VM1
Hankins, KD1
Sample, RH1
Wible, JH1
Lányi, K1
Erdélyi, I1
Tardos, L1
Lovász, M1
Institoris, E1
Stockhaus, K1
Wick, H1
Aust, G1
Van Zwieten, PA1

Other Studies

42 other studies available for carbachol and Anesthesia

ArticleYear
Level of Consciousness Is Dissociable from Electroencephalographic Measures of Cortical Connectivity, Slow Oscillations, and Complexity.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2020, 01-15, Volume: 40, Issue:3

    Topics: Anesthesia; Anesthetics, Inhalation; Animals; Carbachol; Cerebral Cortex; Consciousness Disorders; E

2020
Cell discharge correlates of posterior hypothalamic theta rhythm recorded in anesthetized rats and brain slices.
    Hippocampus, 2016, Volume: 26, Issue:10

    Topics: Action Potentials; Anesthesia; Animals; Carbachol; Cholinergic Agonists; Electrocorticography; Hypot

2016
Characterization of aclidinium bromide, a novel inhaled muscarinic antagonist, with long duration of action and a favorable pharmacological profile.
    The Journal of pharmacology and experimental therapeutics, 2009, Volume: 331, Issue:2

    Topics: Administration, Inhalation; Anesthesia; Animals; Bronchi; Bronchoconstriction; Carbachol; CHO Cells;

2009
Bronchodilator activity of (3R)-3-[[[(3-fluorophenyl)[(3,4,5-trifluorophenyl)methyl]amino] carbonyl]oxy]-1-[2-oxo-2-(2-thienyl)ethyl]-1-azoniabicyclo[2.2.2]octane bromide (CHF5407), a potent, long-acting, and selective muscarinic M3 receptor antagonist.
    The Journal of pharmacology and experimental therapeutics, 2010, Volume: 335, Issue:3

    Topics: Acetylcholine; Aged; Anesthesia; Animals; Blood Pressure; Bronchi; Bronchial Spasm; Bronchoconstrict

2010
Pharmacologic characteristics of bladder micturition function in anesthetized mice.
    Comparative medicine, 2010, Volume: 60, Issue:6

    Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-1 Receptor Antagonists; Adrenergic beta-Agoni

2010
Theta-related gating cells in hippocampal formation: in vivo and in vitro study.
    Hippocampus, 2013, Volume: 23, Issue:1

    Topics: Anesthesia; Animals; Baclofen; Bicuculline; CA1 Region, Hippocampal; CA3 Region, Hippocampal; Carbac

2013
Effects of trimetazidine on myocardial preconditioning in anesthetized rats.
    European journal of pharmacology, 2004, Oct-25, Volume: 503, Issue:1-3

    Topics: Anesthesia; Animals; Arrhythmias, Cardiac; Blood Pressure; Carbachol; Coronary Vessels; Creatine Kin

2004
Detection of mediator-induced airway constriction by barometric plethysmography in mice.
    The Chinese journal of physiology, 2004, Dec-31, Volume: 47, Issue:4

    Topics: Air Pressure; Airway Resistance; Anesthesia; Animals; Bradykinin; Carbachol; Constriction, Pathologi

2004
Spatiotemporal gating of sensory inputs in thalamus during quiescent and activated states.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2005, Nov-23, Volume: 25, Issue:47

    Topics: Anesthesia; Animals; Arousal; Behavior, Animal; Carbachol; Cholinergic Agonists; Electric Stimulatio

2005
Effects of fasudil, a Rho-kinase inhibitor, on myocardial preconditioning in anesthetized rats.
    European journal of pharmacology, 2005, Dec-19, Volume: 527, Issue:1-3

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Anesthesia; Animals; Blood Pressure; Carbachol; Cardi

2005
Cholinergic regulation of the posterior medial thalamic nucleus.
    Journal of neurophysiology, 2006, Volume: 96, Issue:5

    Topics: Adjuvants, Anesthesia; Anesthesia; Animals; Carbachol; Data Interpretation, Statistical; Electric St

2006
Comparative in vivo uroselectivity profiles of anticholinergics, tested in a novel anesthetized rabbit model.
    European journal of pharmacology, 2007, Oct-31, Volume: 572, Issue:2-3

    Topics: Anesthesia; Animals; Benzhydryl Compounds; Benzofurans; Carbachol; Cholinergic Antagonists; Cresols;

2007
Effects of intravenously and orally administered solifenacin succinate (YM905) on carbachol-induced intravesical pressure elevation and salivary secretion in mice.
    Biological & pharmaceutical bulletin, 2007, Volume: 30, Issue:12

    Topics: Administration, Oral; Anesthesia; Animals; Blood Pressure; Carbachol; Injections, Intravenous; Mice;

2007
Discovery of a novel series of biphenyl benzoic acid derivatives as potent and selective human beta3-adrenergic receptor agonists with good oral bioavailability. Part I.
    Journal of medicinal chemistry, 2008, Mar-27, Volume: 51, Issue:6

    Topics: Administration, Oral; Adrenergic beta-3 Receptor Agonists; Adrenergic beta-Agonists; Anesthesia; Ani

2008
Modulation of hippocampal theta rhythm by the opioid system of the pedunculopontine tegmental nucleus.
    Acta neurobiologiae experimentalis, 2007, Volume: 67, Issue:4

    Topics: Analgesics, Opioid; Anesthesia; Animals; Carbachol; Cholinergic Agonists; Cholinergic Fibers; Hippoc

2007
Centrally induced vasopressor and sympathetic nerve responses to carbachol in rats.
    Japanese circulation journal, 1984, Volume: 48, Issue:2

    Topics: Anesthesia; Animals; Blood Pressure; Carbachol; Cordotomy; Dose-Response Relationship, Drug; Female;

1984
Cardiovascular responses of rats to intrahypothalamic injection of carbachol and noradrenaline.
    British journal of pharmacology, 1983, Volume: 79, Issue:3

    Topics: Anesthesia; Animals; Blood Pressure; Carbachol; Cardiovascular System; Heart Rate; Hypothalamus, Ant

1983
Influence of metiamide and atropine on acid and pepsin secretion in the anaesthetized Heidenhain cat.
    Agents and actions, 1981, Volume: 11, Issue:1-2

    Topics: Anesthesia; Animals; Atropine; Carbachol; Cats; Drug Interactions; Gastric Acid; Histamine; Male; Me

1981
Bronchodilator effects of prostacyclin (PGI2) in dogs and guinea pigs.
    European journal of pharmacology, 1980, Aug-22, Volume: 66, Issue:1

    Topics: 6-Ketoprostaglandin F1 alpha; Anesthesia; Animals; Bronchodilator Agents; Carbachol; Dogs; Epoproste

1980
Regional cerebral blood flow responses to neurochemical stimulation of the substantia innominata in the anaesthetized rat.
    Neuroscience letters, 1995, May-05, Volume: 190, Issue:2

    Topics: Anesthesia; Animals; Carbachol; Cerebrovascular Circulation; Cholinergic Agonists; Glutamic Acid; Ma

1995
Cardiovascular effects of centrally active cholinomimetics in conscious and anesthetized rats: the role of amygdala.
    Brain research bulletin, 1995, Volume: 37, Issue:6

    Topics: Amygdala; Anesthesia; Animals; Blood Pressure; Carbachol; Cholinergic Agents; Electric Stimulation;

1995
Cardiovascular effects of central administration of cholinomimetics in anesthetized cats.
    Neuropharmacology, 1993, Volume: 32, Issue:2

    Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Administration, Topical; Anest

1993
Quantification of nasal involvement in a guinea pig plethysmograph.
    Journal of applied physiology (Bethesda, Md. : 1985), 1994, Volume: 76, Issue:4

    Topics: Aerosols; Aging; Airway Resistance; Anesthesia; Animals; Carbachol; Dose-Response Relationship, Drug

1994
Hippocampal EEG responses induced by carbachol and atropine infusions into the septum and the hippocampus in the urethane-anaesthetized rat.
    Brain research, 1993, Dec-24, Volume: 631, Issue:2

    Topics: Anesthesia; Animals; Atropine; Brain; Carbachol; Electroencephalography; Hippocampus; Injections; Ma

1993
State-dependent phenomena in cat masseter motoneurons.
    Brain research, 1996, May-25, Volume: 722, Issue:1-2

    Topics: Anesthesia; Animals; Carbachol; Cats; Chloralose; Electrophysiology; Geniculate Bodies; Masseter Mus

1996
Peripheral effects of three novel non-peptide tachykinin NK1 receptor antagonists in the anaesthetized rat.
    European journal of pharmacology, 1996, Dec-30, Volume: 318, Issue:2-3

    Topics: Anesthesia; Animals; Blood Pressure; Carbachol; Dose-Response Relationship, Drug; Male; Neurokinin-1

1996
Characterization of nociceptin receptors in the periphery: in vitro and in vivo studies.
    Naunyn-Schmiedeberg's archives of pharmacology, 1999, Volume: 359, Issue:3

    Topics: Anesthesia; Animals; Carbachol; Electric Stimulation; Guinea Pigs; Hemodynamics; Ileum; In Vitro Tec

1999
Pontine carbachol elicits multiple rapid eye movement sleep-like neural events in urethane-anaesthetized rats.
    Neuroscience, 1999, Volume: 93, Issue:1

    Topics: Anesthesia; Animals; Atropine; Carbachol; Cortical Synchronization; Electroencephalography; Male; Mi

1999
Pontine cholinergic mechanisms enhance trigeminally evoked respiratory suppression in the anesthetized rat.
    Journal of applied physiology (Bethesda, Md. : 1985), 1999, Volume: 87, Issue:3

    Topics: Anesthesia; Animals; Blood Pressure; Carbachol; Electric Stimulation; Electromyography; Heart Rate;

1999
Effects of cholinomimetic injection into the brain stem reticular formation on halothane anesthesia and antinociception in rats.
    The Journal of pharmacology and experimental therapeutics, 2000, Volume: 293, Issue:3

    Topics: Analgesia; Anesthesia; Anesthetics, Inhalation; Animals; Atropine; Carbachol; Dose-Response Relation

2000
The effect of clonidine on gastric acid secretion in rats and dogs.
    Naunyn-Schmiedeberg's archives of pharmacology, 1977, Volume: 297, Issue:1

    Topics: Anesthesia; Animals; Carbachol; Clonidine; Dogs; Drug Interactions; Female; Gastric Fistula; Gastric

1977
Anaesthetic doses of pentobarbital antagonize phosphatidylinositol hydrolysis induced by substance P or carbachol in the spinal cord and cerebral cortex of the rat.
    European journal of pharmacology, 1992, Sep-01, Volume: 227, Issue:1

    Topics: Anesthesia; Animals; Carbachol; Cerebral Cortex; Hydrolysis; In Vitro Techniques; Pentobarbital; Pho

1992
Cholinergic modulation of responses to glutamate in the thalamic reticular nucleus of the anesthetized rat.
    Brain research, 1991, Aug-23, Volume: 557, Issue:1-2

    Topics: Anesthesia; Animals; Carbachol; Chloral Hydrate; Electric Stimulation; Electroencephalography; Gluta

1991
Cardiovascular effects of bromocriptine in rats: role of peripheral adrenergic and dopaminergic receptors.
    Journal of autonomic pharmacology, 1990, Volume: 10, Issue:2

    Topics: Anesthesia; Animals; Blood Pressure; Bromocriptine; Carbachol; Decerebrate State; Electric Stimulati

1990
Influence of capsaicin-sensitive afferent neurones on the acid secretory responses of the rat stomach in vivo.
    British journal of pharmacology, 1990, Volume: 100, Issue:3

    Topics: Anesthesia; Animals; Blood Glucose; Capsaicin; Carbachol; Female; Ganglia, Sympathetic; Gastric Acid

1990
Autoregulation of renal blood flow during the infusion of acetylcholine or carbachol in anaesthetized dogs.
    The Journal of pharmacy and pharmacology, 1987, Volume: 39, Issue:6

    Topics: Acetylcholine; Anesthesia; Animals; Blood Pressure; Carbachol; Dogs; Female; Infusions, Intravenous;

1987
Central gastric antisecretory action of adenosine in the rat.
    European journal of pharmacology, 1988, Feb-16, Volume: 147, Issue:1

    Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Anesthesia; Animals; Biogenic Amines; Brain Chemistry;

1988
Effect of Rumex nepalensis extracts on histamine, acetylcholine, carbachol, bradykinin, and PGs evoked skin reactions in rabbits.
    Annals of allergy, 1986, Volume: 56, Issue:2

    Topics: Acetylcholine; Alprostadil; Analgesia; Anesthesia; Animals; Bradykinin; Carbachol; Dinoprost; Dinopr

1986
Microinjection of GABA antagonists into posterior hypothalamus elevates heart rate in anesthetized rats.
    Neuropharmacology, 1986, Volume: 25, Issue:9

    Topics: Anesthesia; Animals; Bicuculline; Blood Pressure; Carbachol; GABA Antagonists; Heart Rate; Hypothala

1986
[Piperazine derivatives. 3. Effect of carbonyl- and hydroxy-derivatives (1)].
    Die Pharmazie, 1970, Volume: 25, Issue:3

    Topics: Analgesics; Anesthesia; Animals; Antihypertensive Agents; Barium; Blood Pressure; Body Temperature;

1970
[Modification of gastric juice secretion by saliva of rats with pyloric ligation (Shay rats)].
    Arzneimittel-Forschung, 1970, Volume: 20, Issue:6

    Topics: Anesthesia; Animals; Buffers; Carbachol; Esophagus; Gastric Acidity Determination; Gastric Juice; Hy

1970
The influence of 1-[3-(1-cyclohexenyl)-3-phenylpropyl]-1-methylpiperidinium bromide (HOE 019) on gastric secretion in the rat.
    Arzneimittel-Forschung, 1970, Volume: 20, Issue:8

    Topics: Anesthesia; Animals; Atropine; Carbachol; Cyclohexanes; Depression, Chemical; Electric Stimulation;

1970