Page last updated: 2024-11-07

carbachol and Alzheimer Disease

carbachol has been researched along with Alzheimer Disease in 46 studies

Carbachol: A slowly hydrolyzed CHOLINERGIC AGONIST that acts at both MUSCARINIC RECEPTORS and NICOTINIC RECEPTORS.

Alzheimer Disease: A degenerative disease of the BRAIN characterized by the insidious onset of DEMENTIA. Impairment of MEMORY, judgment, attention span, and problem solving skills are followed by severe APRAXIAS and a global loss of cognitive abilities. The condition primarily occurs after age 60, and is marked pathologically by severe cortical atrophy and the triad of SENILE PLAQUES; NEUROFIBRILLARY TANGLES; and NEUROPIL THREADS. (From Adams et al., Principles of Neurology, 6th ed, pp1049-57)

Research Excerpts

ExcerptRelevanceReference
"For patients with Alzheimer's disease, no correlation was obtained between age and S."5.28[Changes in DNA synthesis in lymphocytes induced by carbachol via muscarinic acetylcholine receptor in relation to aging and Alzheimer's disease in females]. ( Furukawa, Y, 1992)
" Young males showed greater responsiveness to both drugs than young females, this being reflected in higher maxima of the dose-response curves obtained for the males."5.27The responsiveness of human eccrine sweat glands to choline and carbachol. Application to the study of peripheral cholinergic functioning in Alzheimer-type dementia. ( Bradshaw, CM; Lamb, K; Szabadi, E, 1983)
"The relative proportion of super-high, high and low affinity agonist binding sites was measured in the hippocampus from individuals with dementia of the Alzheimer type (AD/SDAT), mixed (AD-MID) type and controls, using labelled quinuclidinyl benzilate ([3H]QNB) competing with unlabelled carbachol."3.67Muscarinic receptor subtypes in hippocampus in Alzheimer's disease and mixed dementia type. ( Alafuzoff, I; Nordberg, A; Winblad, B, 1986)
"Carbachol was a chemoattractant for microglia and decreased their phagocytic activity."1.43The subpopulation of microglia expressing functional muscarinic acetylcholine receptors expands in stroke and Alzheimer's disease. ( Endres, M; Kettenmann, H; Kronenberg, G; Matyash, V; Meier, MA; Pannell, M; Prinz, V; Szulzewsky, F; Waiczies, S; Wolf, SA, 2016)
"Neurochemical alterations in Alzheimer's disease (AD) include cholinergic neuronal loss in the nucleus basalis of Meynert (nbM) and a decrease in densities of the M2 muscarinic receptor subtype in areas related to learning and memory."1.43Activity of muscarinic, galanin and cannabinoid receptors in the prodromal and advanced stages in the triple transgenic mice model of Alzheimer's disease. ( Giménez-Llort, L; LaFerla, FM; Lombardero, L; Manuel, I; Rodríguez-Puertas, R, 2016)
"The study of late-onset/age-related Alzheimer's disease (AD)(sporadic AD, 95% of AD cases) has been hampered by a paucity of animal models."1.42Characterization of Aldh2 (-/-) mice as an age-related model of cognitive impairment and Alzheimer's disease. ( Andrew, RD; Bennett, BM; D'Souza, Y; Elharram, A; Soon-Shiong, R, 2015)
"Our previous studies indicated that Alzheimer's disease (AD) related amyloid beta peptide (Abeta) significantly altered muscarinic cholinergic receptor (mChR) signaling on the level of G protein regulated phospholipase C (PLC) leading to the lower formation of inositol-1,4,5-triphosphate (IP3) and diacylglycerol (DAG)."1.33Alzheimer's disease related peptides affected cholinergic receptor mediated poly(ADP-ribose) polymerase activity in the hippocampus. ( Adamczyk, A; Jeśko, H; Strosznajder, RP, 2005)
"The senile plaque in Alzheimer's disease (AD) consists mainly of the amyloid beta-peptide (A beta) derived from a larger beta-amyloid precursor protein (betaAPP)."1.30The effect of tacrine and leupeptin on the secretion of the beta-amyloid precursor protein in HeLa cells. ( Farlow, MR; Lahiri, DK; Nall, C; Sambamurti, K, 1997)
"The effects of Alzheimer's disease (AD) on [35S]GTP gamma S binding to G proteins was examined in postmortem cerebrocortex."1.29Receptor-mediated activation of G proteins is reduced in postmortem brains from Alzheimer's disease patients. ( Friedman, E; Wang, HY, 1994)
"For patients with Alzheimer's disease, no correlation was obtained between age and S."1.28[Changes in DNA synthesis in lymphocytes induced by carbachol via muscarinic acetylcholine receptor in relation to aging and Alzheimer's disease in females]. ( Furukawa, Y, 1992)
" Young males showed greater responsiveness to both drugs than young females, this being reflected in higher maxima of the dose-response curves obtained for the males."1.27The responsiveness of human eccrine sweat glands to choline and carbachol. Application to the study of peripheral cholinergic functioning in Alzheimer-type dementia. ( Bradshaw, CM; Lamb, K; Szabadi, E, 1983)
"Tacrine was a weak competitor of [3H]phenylisopropyladenosine ([3H]L-PIA) binding in brain membranes."1.27Blockade of a cardiac K+ channel by tacrine: interactions with muscarinic and adenosine receptors. ( Freeman, SE; Lau, WM; Szilagyi, M, 1988)

Research

Studies (46)

TimeframeStudies, this research(%)All Research%
pre-19907 (15.22)18.7374
1990's21 (45.65)18.2507
2000's11 (23.91)29.6817
2010's7 (15.22)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Dunbar, PG1
Durant, GJ1
Rho, T1
Ojo, B1
Huzl, JJ1
Smith, DA1
el-Assadi, AA1
Sbeih, S1
Ngur, DO1
Periyasamy, S1
Bromidge, SM1
Brown, F1
Cassidy, F1
Clark, MS1
Dabbs, S1
Hadley, MS1
Hawkins, J1
Loudon, JM1
Naylor, CB1
Orlek, BS1
Riley, GJ1
Honarnejad, K2
Kirsch, AK1
Daschner, A2
Szybinska, A2
Kuznicki, J2
Herms, J2
Giese, A1
Zall, A1
Schmidt, B1
Pannell, M1
Meier, MA1
Szulzewsky, F1
Matyash, V1
Endres, M1
Kronenberg, G1
Prinz, V1
Waiczies, S1
Wolf, SA1
Kettenmann, H1
D'Souza, Y1
Elharram, A1
Soon-Shiong, R1
Andrew, RD1
Bennett, BM1
Manuel, I1
Lombardero, L1
LaFerla, FM1
Giménez-Llort, L1
Rodríguez-Puertas, R1
Akay, M2
Wang, K2
Akay, YM2
Dragomir, A2
Wu, J2
Hicks, DA1
Makova, NZ1
Nalivaeva, NN1
Turner, AJ1
Muma, NA1
Mariyappa, R1
Williams, K1
Lee, JM3
Zhong, P1
Gu, Z1
Wang, X1
Jiang, H1
Feng, J1
Yan, Z1
Shiozaki, K1
Iseki, E1
Magdesian, MH1
Nery, AA1
Martins, AH1
Juliano, MA1
Juliano, L1
Ulrich, H1
Ferreira, ST1
Adamczyk, A1
Jeśko, H1
Strosznajder, RP1
Schliebs, R1
Heidel, K1
Apelt, J1
Gniezdzinska, M1
Kirazov, L1
Szutowicz, A1
Warren, NM1
Piggott, MA1
Lees, AJ1
Perry, EK2
Burn, DJ1
Lamb, K1
Bradshaw, CM1
Szabadi, E1
Alder, JT1
Chessell, IP2
Bowen, DM1
Ladner, CJ2
Celesia, GG1
Magnuson, DJ1
Ferrari-DiLeo, G2
Mash, DC3
Flynn, DD4
Wolf, BA1
Wertkin, AM1
Jolly, YC1
Yasuda, RP1
Wolfe, BB1
Konrad, RJ1
Manning, D1
Ravi, S1
Williamson, JR1
Lee, VM1
Cutler, R1
Joseph, JA1
Yamagami, K1
Villalobos-Molina, R1
Roth, GS1
Wang, HY1
Friedman, E1
Warpman, U1
Alafuzoff, I2
Nordberg, A2
Humphrey, PP1
Chessell, JP1
Lahiri, DK1
Farlow, MR1
Sambamurti, K1
Nall, C1
DeLapp, N1
Wu, S1
Belagaje, R1
Johnstone, E1
Little, S1
Shannon, H1
Bymaster, F1
Calligaro, D1
Mitch, C1
Whitesitt, C1
Ward, J1
Sheardown, M1
Fink-Jensen, A1
Jeppesen, L1
Thomsen, C1
Sauerberg, P1
Fowler, CJ1
Tiger, G1
Forlenza, OV1
Spink, JM1
Dayanandan, R1
Anderton, BH1
Olesen, OF1
Lovestone, S1
Pettit, DL1
Shao, Z1
Yakel, JL1
Cedazo-Mínguez, A1
Hamker, U1
Meske, V1
Veh, RW1
Hellweg, R1
Jacobi, C1
Albert, F1
Cowburn, RF1
Ohm, TG1
Nitsch, RM1
Slack, BE1
Wurtman, RJ1
Growdon, JH1
Furukawa, Y1
Weinstein, DA1
Fulop, T1
Kekessy, D1
Foris, G1
Smith, CJ1
Court, JA1
Perry, RH1
Araujo, DM2
Lapchak, PA2
Collier, B1
Quirion, R2
Rinne, JO1
Lönnberg, P1
Marjamäki, P1
Rinne, UK1
Freeman, SE1
Lau, WM1
Szilagyi, M1
Robitaille, Y1
Gauthier, S1
Winblad, B1

Reviews

1 review available for carbachol and Alzheimer Disease

ArticleYear
N-[3H]methylcarbamylcholine binding sites in the rat and human brain: relationship to functional nicotinic autoreceptors and alterations in Alzheimer's disease.
    Progress in brain research, 1989, Volume: 79

    Topics: Alzheimer Disease; Animals; Brain Chemistry; Carbachol; Humans; Radioligand Assay; Rats; Receptors,

1989

Other Studies

45 other studies available for carbachol and Alzheimer Disease

ArticleYear
Design, synthesis, and neurochemical evaluation of 2-amino-5-(alkoxycarbonyl)-3,4,5,6-tetrahydropyridines and 2-amino-5-(alkoxycarbonyl)-1,4,5,6-tetrahydropyrimidines as M1 muscarinic receptor agonists.
    Journal of medicinal chemistry, 1994, Aug-19, Volume: 37, Issue:17

    Topics: Alzheimer Disease; Animals; Cerebral Cortex; Drug Design; Humans; In Vitro Techniques; Indicators an

1994
Design of [R-(Z)]-(+)-alpha-(methoxyimino)-1-azabicyclo[2.2.2]octane-3-acetonitri le (SB 202026), a functionally selective azabicyclic muscarinic M1 agonist incorporating the N-methoxy imidoyl nitrile group as a novel ester bioisostere.
    Journal of medicinal chemistry, 1997, Dec-19, Volume: 40, Issue:26

    Topics: Alzheimer Disease; Animals; Binding Sites; Blood Pressure; Brain; CHO Cells; Cricetinae; Electroence

1997
FRET-based calcium imaging: a tool for high-throughput/content phenotypic drug screening in Alzheimer disease.
    Journal of biomolecular screening, 2013, Volume: 18, Issue:10

    Topics: Alzheimer Disease; Bacterial Proteins; Calcium Signaling; Calmodulin-Binding Proteins; Carbachol; Dr

2013
Development and implementation of a high-throughput compound screening assay for targeting disrupted ER calcium homeostasis in Alzheimer's disease.
    PloS one, 2013, Volume: 8, Issue:11

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Calcium; Calcium Channels; Carbachol; Cell Line; Drug Disc

2013
The subpopulation of microglia expressing functional muscarinic acetylcholine receptors expands in stroke and Alzheimer's disease.
    Brain structure & function, 2016, Volume: 221, Issue:2

    Topics: Alzheimer Disease; Animals; Brain; Carbachol; Disease Models, Animal; Female; Glioma; Macrophages; M

2016
Characterization of Aldh2 (-/-) mice as an age-related model of cognitive impairment and Alzheimer's disease.
    Molecular brain, 2015, Apr-25, Volume: 8

    Topics: Aging; Aldehyde Dehydrogenase; Aldehyde Dehydrogenase, Mitochondrial; Aldehydes; Alzheimer Disease;

2015
Activity of muscarinic, galanin and cannabinoid receptors in the prodromal and advanced stages in the triple transgenic mice model of Alzheimer's disease.
    Neuroscience, 2016, 08-04, Volume: 329

    Topics: Aging; Alzheimer Disease; Animals; Autoradiography; Brain; Carbachol; Disease Models, Animal; Diseas

2016
Nonlinear dynamical analysis of carbachol induced hippocampal oscillations in mice.
    Acta pharmacologica Sinica, 2009, Volume: 30, Issue:6

    Topics: Age Factors; Alzheimer Disease; Animals; Carbachol; Cholinergic Agonists; Disease Models, Animal; El

2009
Decoding state transitions in hippocampal oscillatory activity in mice.
    Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference, 2010, Volume: 2010

    Topics: Alzheimer Disease; Animals; Carbachol; Disease Models, Animal; Hippocampus; Markov Chains; Mice; Mic

2010
Characterisation of acetylcholinesterase release from neuronal cells.
    Chemico-biological interactions, 2013, Mar-25, Volume: 203, Issue:1

    Topics: Acetylcholinesterase; Alzheimer Disease; Animals; Atropine; Butyrylcholinesterase; Carbachol; Cell L

2013
Differences in regional and subcellular localization of G(q/11) and RGS4 protein levels in Alzheimer's disease: correlation with muscarinic M1 receptor binding parameters.
    Synapse (New York, N.Y.), 2003, Volume: 47, Issue:1

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Autopsy; Brain; Brain Chemistry; Carbachol; Case-Control

2003
Impaired modulation of GABAergic transmission by muscarinic receptors in a mouse transgenic model of Alzheimer's disease.
    The Journal of biological chemistry, 2003, Jul-18, Volume: 278, Issue:29

    Topics: Action Potentials; Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Carbachol; Disease Mo

2003
Decrease in GTP-sensitive high affinity agonist binding of muscarinic acetylcholine receptors in autopsied brains of dementia with Lewy bodies and Alzheimer's disease.
    Journal of the neurological sciences, 2004, Aug-30, Volume: 223, Issue:2

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Analysis of Variance; Autopsy; Binding, Competitive; Bra

2004
Peptide blockers of the inhibition of neuronal nicotinic acetylcholine receptors by amyloid beta.
    The Journal of biological chemistry, 2005, Sep-02, Volume: 280, Issue:35

    Topics: Alzheimer Disease; Amino Acid Sequence; Amyloid beta-Peptides; Animals; Carbachol; Cholinergic Agoni

2005
Alzheimer's disease related peptides affected cholinergic receptor mediated poly(ADP-ribose) polymerase activity in the hippocampus.
    Folia neuropathologica, 2005, Volume: 43, Issue:3

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Calcium Channel Blockers; Calcium Channels; Carba

2005
Interaction of interleukin-1beta with muscarinic acetylcholine receptor-mediated signaling cascade in cholinergically differentiated SH-SY5Y cells.
    Brain research, 2006, Nov-29, Volume: 1122, Issue:1

    Topics: Acetylcholinesterase; Alzheimer Disease; Carbachol; Cholinergic Agonists; Dose-Response Relationship

2006
Intact coupling of M1 receptors and preserved M2 and M4 receptors in the cortex in progressive supranuclear palsy: contrast with other dementias.
    Journal of chemical neuroanatomy, 2008, Volume: 35, Issue:3

    Topics: Alzheimer Disease; Atropine; Autoradiography; Carbachol; Cerebral Cortex; Dementia; Humans; Lewy Bod

2008
The responsiveness of human eccrine sweat glands to choline and carbachol. Application to the study of peripheral cholinergic functioning in Alzheimer-type dementia.
    European journal of clinical pharmacology, 1983, Volume: 24, Issue:1

    Topics: Adult; Aged; Aging; Alzheimer Disease; Carbachol; Choline; Dementia; Dose-Response Relationship, Dru

1983
A neurochemical approach for studying response to acetylcholine in Alzheimer's disease.
    Neurochemical research, 1995, Volume: 20, Issue:7

    Topics: Acetylcholine; Alzheimer Disease; Animals; Biomarkers; Carbachol; Cholinergic Agents; Frontal Lobe;

1995
Regional alterations in M1 muscarinic receptor-G protein coupling in Alzheimer's disease.
    Journal of neuropathology and experimental neurology, 1995, Volume: 54, Issue:6

    Topics: Aged; Alzheimer Disease; Binding Sites; Brain; Carbachol; Frontal Lobe; GTP-Binding Proteins; Humans

1995
Attenuation of muscarinic receptor-G-protein interaction in Alzheimer disease.
    Molecular and chemical neuropathology, 1995, Volume: 24, Issue:1

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Carbachol; Cerebral Cortex; Choline O-Acetyltransferase;

1995
Muscarinic regulation of Alzheimer's disease amyloid precursor protein secretion and amyloid beta-protein production in human neuronal NT2N cells.
    The Journal of biological chemistry, 1995, Mar-03, Volume: 270, Issue:9

    Topics: Alzheimer Disease; Amyloid; Amyloid beta-Peptides; Carbachol; Enzyme Activation; Humans; Neurons; Pr

1995
Area specific alterations in muscarinic stimulated low Km GTPase activity in aging and Alzheimer's disease: implications for altered signal transduction.
    Brain research, 1994, Nov-21, Volume: 664, Issue:1-2

    Topics: Aged; Aged, 80 and over; Aging; Alzheimer Disease; Carbachol; Enzyme Activation; GTP Phosphohydrolas

1994
Receptor-mediated activation of G proteins is reduced in postmortem brains from Alzheimer's disease patients.
    Neuroscience letters, 1994, May-23, Volume: 173, Issue:1-2

    Topics: Aged; Alzheimer Disease; Biotransformation; Brain Chemistry; Carbachol; Female; GTP-Binding Proteins

1994
Diminished muscarinic receptor-stimulated [3H]-PIP2 hydrolysis in Alzheimer's disease.
    Life sciences, 1993, Volume: 53, Issue:25

    Topics: Aged; Alzheimer Disease; Binding, Competitive; Carbachol; Cell Membrane; Choline O-Acetyltransferase

1993
Coupling of muscarinic receptors to GTP proteins in postmortem human brain--alterations in Alzheimer's disease.
    Neuroscience letters, 1993, Feb-05, Volume: 150, Issue:1

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Autopsy; Binding, Competitive; Brain; Carbachol; Female;

1993
Nicotinic and muscarinic receptor-evoked depolarizations recorded from a novel cortical brain slice preparation.
    Neuropharmacology, 1995, Volume: 34, Issue:10

    Topics: Alzheimer Disease; Animals; Carbachol; Cerebral Cortex; Dimethylphenylpiperazinium Iodide; Dose-Resp

1995
Acetylcholine receptor targets on cortical pyramidal neurones as targets for Alzheimer's therapy.
    Neurodegeneration : a journal for neurodegenerative disorders, neuroprotection, and neuroregeneration, 1996, Volume: 5, Issue:4

    Topics: Alzheimer Disease; Autoradiography; Carbachol; Cerebral Cortex; Electrophysiology; Glycoproteins; Hu

1996
The effect of tacrine and leupeptin on the secretion of the beta-amyloid precursor protein in HeLa cells.
    Life sciences, 1997, Volume: 61, Issue:20

    Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Carbachol; Cholinesterase Inhibitors; Culture Med

1997
Effects of the M1 agonist xanomeline on processing of human beta-amyloid precursor protein (FAD, Swedish mutant) transfected into Chinese hamster ovary-m1 cells.
    Biochemical and biophysical research communications, 1998, Mar-06, Volume: 244, Issue:1

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Blotting, Western

1998
The sulphydryl oxidizing reagent diamide affects phosphoinositide-mediated signal transduction: implications for the pathogenesis of Alzheimer's disease.
    Cellular signalling, 1998, Volume: 10, Issue:6

    Topics: Alzheimer Disease; Animals; Blood Platelets; Brain; Calcium Signaling; Carbachol; Diamide; Dithiothr

1998
Reduced high-affinity agonist binding at the M(1) muscarinic receptor in Alzheimer's disease brain: differential sensitivity to agonists and divalent cations.
    Experimental neurology, 1999, Volume: 158, Issue:2

    Topics: Acetylcholine; Aged; Alzheimer Disease; Brain; Carbachol; Cations, Divalent; Chlorides; Edetic Acid;

1999
Muscarinic agonists reduce tau phosphorylation in non-neuronal cells via GSK-3beta inhibition and in neurons.
    Journal of neural transmission (Vienna, Austria : 1996), 2000, Volume: 107, Issue:10

    Topics: Acetylcholine; Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Binding Sites; Calcium-Ca

2000
beta-Amyloid(1-42) peptide directly modulates nicotinic receptors in the rat hippocampal slice.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2001, Jan-01, Volume: 21, Issue:1

    Topics: Acetylcholine; Alzheimer Disease; Amyloid beta-Peptides; Animals; Carbachol; Cognition Disorders; Do

2001
Regulation of apolipoprotein E secretion in rat primary hippocampal astrocyte cultures.
    Neuroscience, 2001, Volume: 105, Issue:3

    Topics: Alzheimer Disease; Animals; Animals, Newborn; Apolipoproteins E; Astrocytes; Bucladesine; Carbachol;

2001
Release of Alzheimer amyloid precursor derivatives stimulated by activation of muscarinic acetylcholine receptors.
    Science (New York, N.Y.), 1992, Oct-09, Volume: 258, Issue:5080

    Topics: Alkaloids; Alzheimer Disease; Amyloid beta-Protein Precursor; Atropine; Blotting, Western; Brain Che

1992
[Changes in DNA synthesis in lymphocytes induced by carbachol via muscarinic acetylcholine receptor in relation to aging and Alzheimer's disease in females].
    Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics, 1992, Volume: 29, Issue:12

    Topics: Adult; Aged; Aging; Alzheimer Disease; Carbachol; Cells, Cultured; DNA; Female; Humans; Lymphocytes;

1992
Loss of high-affinity agonist binding to M1 muscarinic receptors in Alzheimer's disease: implications for the failure of cholinergic replacement therapies.
    Annals of neurology, 1991, Volume: 29, Issue:3

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Carbachol; Choline O-Acetyltransferase; Female; Frontal

1991
Altered post-receptorial signal transduction mechanism under various stimulation in polymorphonuclear granulocytes of Alzheimer's disease.
    Mechanisms of ageing and development, 1990, Mar-15, Volume: 52, Issue:2-3

    Topics: Aged; Aged, 80 and over; Aging; Alzheimer Disease; Carbachol; Cyclic AMP; Cyclic GMP; Enkephalin, Me

1990
Cholinergic nicotinic and muscarinic receptors in dementia of Alzheimer, Parkinson and Lewy body types.
    Journal of neural transmission. Parkinson's disease and dementia section, 1990, Volume: 2, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Alzheimer Disease; Brain Chemistry; Carbachol; Choline O-Acetyltrans

1990
Brain muscarinic receptor subtypes are differently affected in Alzheimer's disease and Parkinson's disease.
    Brain research, 1989, Apr-03, Volume: 483, Issue:2

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Brain; Carbachol; Choline O-Acetyltransferase; Cholinerg

1989
Blockade of a cardiac K+ channel by tacrine: interactions with muscarinic and adenosine receptors.
    European journal of pharmacology, 1988, Sep-01, Volume: 154, Issue:1

    Topics: Action Potentials; Adenosine; Alzheimer Disease; Aminoacridines; Animals; Carbachol; Guinea Pigs; He

1988
Differential alteration of various cholinergic markers in cortical and subcortical regions of human brain in Alzheimer's disease.
    Journal of neurochemistry, 1988, Volume: 50, Issue:6

    Topics: Acetylcholine; Aged; Aged, 80 and over; Alzheimer Disease; Brain; Carbachol; Cerebral Cortex; Cholin

1988
Characterization of L-[3H]nicotine binding in human cerebral cortex: comparison between Alzheimer's disease and the normal.
    Journal of neurochemistry, 1986, Volume: 47, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Aging; Alzheimer Disease; Animals; Carbachol; Cerebral Cortex; Choli

1986
Muscarinic receptor subtypes in hippocampus in Alzheimer's disease and mixed dementia type.
    Neuroscience letters, 1986, Sep-25, Volume: 70, Issue:1

    Topics: Aged; Alzheimer Disease; Carbachol; Dementia; Female; Hippocampus; Humans; Male; Quinuclidinyl Benzi

1986