carbachol has been researched along with Airway Hyper-Responsiveness in 32 studies
Carbachol: A slowly hydrolyzed CHOLINERGIC AGONIST that acts at both MUSCARINIC RECEPTORS and NICOTINIC RECEPTORS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Ozone, a pollutant known to induce airway hyper-responsiveness (AHR), increases morbidity and mortality in patients with obstructive airway diseases and asthma." | 7.76 | 20-HETE mediates ozone-induced, neutrophil-independent airway hyper-responsiveness in mice. ( Blair, IA; Christmas, P; Cooper, PR; Douaidy, K; Mesaros, AC; Mittelman, MA; Panettieri, RA; Soberman, RJ; Stark, CM; Zhang, J, 2010) |
| " The aim of this study was to investigate the effects of desflurane at different concentrations and durations in an ovalbumin-sensitized guinea pig model of airway hyper-responsiveness." | 3.85 | Time- and Dose-Dependent Effects of Desflurane in Sensitized Airways. ( Iwasaki, S; Yamakage, M; Zhou, J, 2017) |
| "Ovalbumin (OVA)-sensitized rats were actively challenged with saline or OVA to study airway hyper-responsiveness after oral treatment with saline or Jp." | 3.85 | Inhibitory effects of a standardized extract of Justicia pectoralis in an experimental rat model of airway hyper-responsiveness. ( Aragão, KS; Batista-Lima, FJ; Brito, TS; Ferreira, LC; Fonseca, FN; Havt, A; Leal, LKAM; Magalhães, PJC; Moura, CTM; Roque, CR; Silva, AAV, 2017) |
| "Ozone, a pollutant known to induce airway hyper-responsiveness (AHR), increases morbidity and mortality in patients with obstructive airway diseases and asthma." | 3.76 | 20-HETE mediates ozone-induced, neutrophil-independent airway hyper-responsiveness in mice. ( Blair, IA; Christmas, P; Cooper, PR; Douaidy, K; Mesaros, AC; Mittelman, MA; Panettieri, RA; Soberman, RJ; Stark, CM; Zhang, J, 2010) |
| " Respiratory health was evaluated by determination of bronchial reactivity to Carbachol in 5 diagnostic groups (healthy: 109; healthy with positive family history of atopy: 60; allergic but not asthma: 59; asthma: 55; and "unclear cough": 29) by the technique of group specific sampling." | 3.67 | [Effect of air pollutant burden on healthy children and children with lung diseases in southern Ticino]. ( D'Apuzzo, V; Gschwend-Eigenmann, S; Kraemer, R; Schöni, MH, 1989) |
| "By measuring airway resistance (Raw) as an index of response, dose-response curves to aerosolized carbachol were constructed in 10 patients suffering from grass pollen allergy." | 2.65 | Seasonal increase of carbachol airway responsiveness in patients allergic to grass pollen. Reversal by corticosteroids. ( Badier, M; Orehek, J; Sotomayor, H; Vervloet, D, 1984) |
| " Airway responsiveness was determined from the slopes of dose-response curves of SRL vs." | 1.28 | YM461, a PAF antagonist, blocks antigen-induced late airway responses and airway hyperresponsiveness in allergic sheep. ( Abraham, WM; Ahmed, A; Garrido, R; Stevenson, JS; Tomioka, K, 1989) |
| " For these studies, airway responsiveness was determined from slopes of carbachol dose-response curves (DRC) performed at base line (prechallenge) and 2 h after Ascaris suum antigen challenges in the following three protocols: 1) antigen challenge alone (control trial), 2) WEB-2086 (1 mg/kg iv) given 30 min before antigen challenge (WEB pretreatment), and 3) WEB-2086 given 2 h after antigen challenge, immediately before the postchallenge DRC (WEB posttreatment)." | 1.28 | A PAF antagonist blocks antigen-induced airway hyperresponsiveness and inflammation in sheep. ( Abraham, WM; Sielczak, MW; Solèr, M, 1989) |
| "Linear dose-response relationships can be obtained in vivo by measuring changes in airway conductance induced by graded doses of aerosolized bronchoconstrictor agents." | 1.27 | The concept of airway "sensitivity" and "reactivity". ( Orehek, J, 1983) |
| " These results suggest that verapamil, at the dosage used, did not prevent allergic bronchoconstriction by a direct action on smooth muscle and therefore was effective by inhibiting the release of mast cell mediators." | 1.27 | Modification of allergic bronchoconstriction by a calcium antagonist: mode of action. ( Abraham, WM; Ahmed, T; Marchette, B; Russi, EW; Yerger, L, 1983) |
| "Propranolol treatment increased the bronchial response to intravenously injected methacholine and caused no significant change in the bronchial response to aerosolized methacholine." | 1.26 | Bronchial response to methacholine and histamine in monkeys with beta adrenergic blockade. ( Hida, W; Mue, S; Ohmi, T; Sasaki, T; Shibahara, S; Suzuki, S; Takahashi, M; Takishima, T; Yamauchi, K, 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (40.63) | 18.7374 |
| 1990's | 12 (37.50) | 18.2507 |
| 2000's | 1 (3.13) | 29.6817 |
| 2010's | 5 (15.63) | 24.3611 |
| 2020's | 1 (3.13) | 2.80 |
| Authors | Studies |
|---|---|
| Parikh, V | 1 |
| Scala, J | 1 |
| Patel, R | 1 |
| Corbi, C | 1 |
| Lo, D | 1 |
| Bochkov, YA | 1 |
| Kennedy, JL | 2 |
| Kurten, RC | 2 |
| Liggett, SB | 1 |
| Gern, JE | 1 |
| Koziol-White, CJ | 2 |
| Jeffus, S | 1 |
| Rettiganti, MR | 1 |
| Fisher, P | 1 |
| Kurten, M | 1 |
| Eze, A | 1 |
| House, S | 1 |
| Sikes, JD | 1 |
| Askew, E | 1 |
| Putt, C | 1 |
| Panettieri, RA | 2 |
| Jones, SM | 1 |
| Zhou, J | 1 |
| Iwasaki, S | 1 |
| Yamakage, M | 1 |
| Moura, CTM | 1 |
| Batista-Lima, FJ | 1 |
| Brito, TS | 1 |
| Silva, AAV | 1 |
| Ferreira, LC | 1 |
| Roque, CR | 1 |
| Aragão, KS | 1 |
| Havt, A | 1 |
| Fonseca, FN | 1 |
| Leal, LKAM | 1 |
| Magalhães, PJC | 1 |
| Cooper, PR | 1 |
| Mesaros, AC | 1 |
| Zhang, J | 1 |
| Christmas, P | 1 |
| Stark, CM | 1 |
| Douaidy, K | 1 |
| Mittelman, MA | 1 |
| Soberman, RJ | 1 |
| Blair, IA | 1 |
| Matera, MG | 1 |
| Calzetta, L | 1 |
| Passeri, D | 1 |
| Facciolo, F | 1 |
| Rendina, EA | 1 |
| Page, C | 1 |
| Cazzola, M | 1 |
| Orlandi, A | 1 |
| Moerloose, KB | 1 |
| Pauwels, RA | 1 |
| Joos, GF | 1 |
| Mue, S | 1 |
| Shibahara, S | 1 |
| Suzuki, S | 1 |
| Takahashi, M | 1 |
| Hida, W | 1 |
| Yamauchi, K | 1 |
| Ohmi, T | 1 |
| Sasaki, T | 1 |
| Takishima, T | 1 |
| Orehek, J | 2 |
| Sotomayor, H | 1 |
| Badier, M | 1 |
| Vervloet, D | 1 |
| Russi, EW | 1 |
| Marchette, B | 1 |
| Yerger, L | 1 |
| Abraham, WM | 5 |
| Ahmed, T | 2 |
| Oliver, W | 1 |
| Welker, MJ | 1 |
| King, MM | 1 |
| Wanner, A | 2 |
| Sackner, MA | 1 |
| Jia, Y | 1 |
| Xu, L | 1 |
| Heisler, S | 1 |
| Martin, JG | 1 |
| Finney, MJ | 1 |
| Forsberg, KI | 1 |
| Buckley, TL | 1 |
| Nijkamp, FP | 3 |
| Lansing, MW | 1 |
| Ahmed, A | 2 |
| Cortes, A | 1 |
| Sielczak, MW | 2 |
| Van Loveren, H | 2 |
| Steerenberg, PA | 1 |
| Garssen, J | 2 |
| Van Bree, L | 1 |
| Molinari, JF | 1 |
| Campo, C | 1 |
| Shakir, S | 1 |
| Roux, E | 1 |
| Hyvelin, JM | 1 |
| Savineau, JP | 1 |
| Marthan, R | 1 |
| Schmidt, D | 1 |
| Ruehlmann, E | 1 |
| Branscheid, D | 1 |
| Magnussen, H | 1 |
| Rabe, KF | 1 |
| Miller, MM | 1 |
| Patterson, R | 1 |
| Krell, RD | 1 |
| Salari, H | 1 |
| Yeung, M | 1 |
| Howard, S | 1 |
| Schellenberg, RR | 1 |
| Van der Vliet, H | 1 |
| Bot, H | 1 |
| Urbanek, R | 1 |
| Velcovsky, HG | 1 |
| Discher, T | 1 |
| Gschwend-Eigenmann, S | 1 |
| D'Apuzzo, V | 1 |
| Schöni, MH | 1 |
| Kraemer, R | 1 |
| Tomioka, K | 1 |
| Garrido, R | 1 |
| Stevenson, JS | 1 |
| Solèr, M | 1 |
| Engels, F | 1 |
| Folkerts, G | 1 |
| van Heuven-Nolsen, D | 1 |
| Martinez, FD | 1 |
| Antognoni, G | 1 |
| Macri, F | 1 |
| Bonci, E | 1 |
| Midulla, F | 1 |
| De Castro, G | 1 |
| Ronchetti, R | 1 |
| Klein, G | 1 |
| Matthys, H | 1 |
1 review available for carbachol and Airway Hyper-Responsiveness
| Article | Year |
|---|---|
Interaction of environmental chemicals with respiratory sensitization.
Topics: Air Pollutants; Animals; Carbachol; Environmental Exposure; Humans; Listeriosis; Mice; Ozone; Picryl | 1996 |
1 trial available for carbachol and Airway Hyper-Responsiveness
| Article | Year |
|---|---|
Seasonal increase of carbachol airway responsiveness in patients allergic to grass pollen. Reversal by corticosteroids.
Topics: Adolescent; Adult; Airway Resistance; Carbachol; Dose-Response Relationship, Drug; Female; Humans; M | 1984 |
30 other studies available for carbachol and Airway Hyper-Responsiveness
| Article | Year |
|---|---|
Rhinovirus C15 Induces Airway Hyperresponsiveness via Calcium Mobilization in Airway Smooth Muscle.
Topics: Asthma; Calcium Signaling; Carbachol; Cells, Cultured; Chemokine CXCL10; Enterovirus; Enterovirus In | 2020 |
Effects of rhinovirus 39 infection on airway hyperresponsiveness to carbachol in human airways precision cut lung slices.
Topics: Adult; Carbachol; Female; Humans; Lung; Male; Picornaviridae Infections; Respiratory Hypersensitivit | 2018 |
Time- and Dose-Dependent Effects of Desflurane in Sensitized Airways.
Topics: Airway Resistance; Anesthetics, Inhalation; Animals; Carbachol; Cholinergic Agents; Cyclic AMP; Desf | 2017 |
Inhibitory effects of a standardized extract of Justicia pectoralis in an experimental rat model of airway hyper-responsiveness.
Topics: Animals; Asthma; Bronchoalveolar Lavage Fluid; Calcium; Carbachol; Justicia; Male; Models, Animal; O | 2017 |
20-HETE mediates ozone-induced, neutrophil-independent airway hyper-responsiveness in mice.
Topics: Animals; Bronchial Hyperreactivity; Carbachol; Hydroxyeicosatetraenoic Acids; Lipid Peroxidation; Ma | 2010 |
Epithelium integrity is crucial for the relaxant activity of brain natriuretic peptide in human isolated bronchi.
Topics: Acetylcholine; Bronchi; Carbachol; Cell Culture Techniques; Cholinergic Agonists; Enzyme Inhibitors; | 2011 |
Short-term cigarette smoke exposure enhances allergic airway inflammation in mice.
Topics: Animals; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Carbachol; Chemokines; Cytokines; | 2005 |
Bronchial response to methacholine and histamine in monkeys with beta adrenergic blockade.
Topics: Adrenergic beta-Antagonists; Aerosols; Animals; Bronchi; Carbachol; Female; Haplorhini; Histamine; M | 1980 |
The concept of airway "sensitivity" and "reactivity".
Topics: Airway Resistance; Bronchi; Carbachol; Dose-Response Relationship, Drug; Humans; Muscle, Smooth; Res | 1983 |
Modification of allergic bronchoconstriction by a calcium antagonist: mode of action.
Topics: Airway Resistance; Animals; Antigens; Ascaris; Bronchi; Bronchial Spasm; Carbachol; Histamine Antago | 1983 |
Differences in airway reactivity in normal and allergic sheep after exposure to sulfur dioxide.
Topics: Animals; Ascaris; Carbachol; Dose-Response Relationship, Drug; Respiratory Function Tests; Respirato | 1981 |
Airways of a hyperresponsive rat strain show decreased relaxant responses to sodium nitroprusside.
Topics: Animals; Carbachol; Cyclic GMP; In Vitro Techniques; Male; Methacholine Chloride; Muscle Contraction | 1995 |
Quantification of nasal involvement in a guinea pig plethysmograph.
Topics: Aerosols; Aging; Airway Resistance; Anesthesia; Animals; Carbachol; Dose-Response Relationship, Drug | 1994 |
Airways hyperreactivity and cellular accumulation in a delayed-type hypersensitivity reaction in the mouse. Modulation by capsaicin-sensitive nerves.
Topics: Animals; Bronchoalveolar Lavage Fluid; Calcitonin Gene-Related Peptide; Capsaicin; Carbachol; Dinitr | 1994 |
Oxygen radicals contribute to antigen-induced airway hyperresponsiveness in conscious sheep.
Topics: Aerosols; Analysis of Variance; Animals; Antigens, Helminth; Ascaris suum; Bronchial Hyperreactivity | 1993 |
Inhibition of antigen-induced airway hyperresponsiveness by ultralow molecular-weight heparin.
Topics: Administration, Inhalation; Aerosols; Airway Resistance; Animals; Anticoagulants; Antigens, Helminth | 1998 |
Human isolated airway contraction: interaction between air pollutants and passive sensitization.
Topics: Acrolein; Adult; Air Pollutants; Airway Resistance; Asthma; Bronchi; Bronchial Hyperreactivity; Bron | 1999 |
Passive sensitization of human airways increases responsiveness to leukotriene C4.
Topics: Adult; Aged; Allergens; Asthma; Bronchial Provocation Tests; Bronchoconstriction; Carbachol; Dose-Re | 1999 |
Differential airway reactivity to carbachol and physostigmine sulfate in rhesus monkeys with and without reagin-mediated respiratory responses.
Topics: Aerosols; Animals; Antigens; Ascaris; Asthma; Bronchi; Carbachol; Haplorhini; Macaca mulatta; Physos | 1977 |
Airway hyperreactivity to pharmacologic agents in rhesus monkeys cutaneously hypersensitive to Ascaris antigen.
Topics: Airway Resistance; Animals; Antigens; Ascaris; Carbachol; Disease Models, Animal; Dose-Response Rela | 1976 |
Increased contraction and inositol phosphate formation of tracheal smooth muscle from hyperresponsive guinea pigs.
Topics: Animals; Carbachol; Dose-Response Relationship, Drug; Guinea Pigs; Histamine; Inositol Phosphates; M | 1992 |
A role for T cells in the induction of airway hyperreactivity.
Topics: Animals; Carbachol; Haptens; Hypersensitivity, Delayed; Immunization; Lung; Mice; Mice, Inbred BALB | 1990 |
Allergy and asthma.
Topics: Adolescent; Allergens; Asthma; Bronchial Provocation Tests; Carbachol; Child; Female; Forced Expirat | 1990 |
[Effect of histamine on bronchial hyperreactivity in sarcoidosis and other lung diseases].
Topics: Acetylcholine; Asthma; Bronchial Provocation Tests; Carbachol; Histamine; Humans; Lung Diseases; Res | 1990 |
[Effect of air pollutant burden on healthy children and children with lung diseases in southern Ticino].
Topics: Adolescent; Air Pollutants; Allergens; Asthma; Bronchial Provocation Tests; Carbachol; Child; Female | 1989 |
YM461, a PAF antagonist, blocks antigen-induced late airway responses and airway hyperresponsiveness in allergic sheep.
Topics: Aerosols; Animals; Antigens; Ascaris; Carbachol; Dose-Response Relationship, Drug; Platelet Activati | 1989 |
A PAF antagonist blocks antigen-induced airway hyperresponsiveness and inflammation in sheep.
Topics: Airway Resistance; Animals; Antigens, Helminth; Ascaris; Azepines; Bronchoalveolar Lavage Fluid; Car | 1989 |
Haemophilus influenzae-induced decreases in lung beta-adrenoceptor function and number coincide with decreases in spleen noradrenaline.
Topics: Airway Resistance; Animals; Carbachol; Dihydroalprenolol; Guinea Pigs; Haemophilus influenzae; Isopr | 1987 |
Parental smoking enhances bronchial responsiveness in nine-year-old children.
Topics: Adult; Bronchi; Bronchial Provocation Tests; Carbachol; Child; Female; Humans; Hypersensitivity, Imm | 1988 |
[Bronchial hyperreactivity. Methods of detection with pharmacologic substances].
Topics: Acetylcholine; Airway Obstruction; Asthma; Bronchial Provocation Tests; Carbachol; Histamine; Humans | 1986 |