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carbachol and Aging

carbachol has been researched along with Aging in 192 studies

Carbachol: A slowly hydrolyzed CHOLINERGIC AGONIST that acts at both MUSCARINIC RECEPTORS and NICOTINIC RECEPTORS.

Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.

Research Excerpts

ExcerptRelevanceReference
"For patients with Alzheimer's disease, no correlation was obtained between age and S."5.28[Changes in DNA synthesis in lymphocytes induced by carbachol via muscarinic acetylcholine receptor in relation to aging and Alzheimer's disease in females]. ( Furukawa, Y, 1992)
" Young males showed greater responsiveness to both drugs than young females, this being reflected in higher maxima of the dose-response curves obtained for the males."5.27The responsiveness of human eccrine sweat glands to choline and carbachol. Application to the study of peripheral cholinergic functioning in Alzheimer-type dementia. ( Bradshaw, CM; Lamb, K; Szabadi, E, 1983)
"These results strongly suggest that impaired endothelium dependent and NO mediated cavernous relaxation with aging is due to decreased NO production, which would result from increased arginase activity and probably from decreased L-arginine content."3.72Involvement of increased arginase activity in impaired cavernous relaxation with aging in the rabbit. ( Azuma, H; Kihara, K; Kurosaki, E; Masuda, H; Sakai, Y; Yamauchi, Y, 2004)
" To investigate changes in muscarinic coupling to PLC during aging, we examined carbachol stimulated and calcium stimulated PtdIns hydrolysis in cerebral cortical membranes in young, middle aged and old rats."3.69Age-related loss of cholinergic-muscarinic coupling to PLC: comparison with changes in brain regional PLC subtypes mRNA distribution. ( Ayyagari, PV; Crews, FT; Gerber, M; Joseph, JA; Narang, N, 1996)
"The current study describes the influence of age and the presence of the epithelium on guinea-pig and rat tracheal airway smooth muscle sensitivity to the spasmogens histamine, acetylcholine, carbachol and potassium."3.68Influence of age on epithelium-dependent responsiveness of guinea-pig and rat tracheal smooth muscle to spasmogens. ( Goldie, RG; Henry, PJ; Preuss, JM, 1992)
" The present study was designed to characterize the positive inotropic response to DPI 201-106 in isolated papillary muscle strips obtained from heart failure patients undergoing surgery."3.67Inotropic response to DPI 201-106 in the failing human heart. ( Böhm, M; Diet, F; Erdmann, E; Kemkes, B; Wankerl, M, 1989)
"The ability of the muscarinic receptor agonist, carbachol, to inhibit beta-adrenergic activation of adenylate cyclase was examined in cardiac membranes from 6-month (young adult) and 24-month (aged) old rats in an effort to assess the effect of aging on adrenergic-cholinergic interactions in the heart."3.67Autonomic interactions in the aging heart: age-associated decrease in muscarinic cholinergic receptor mediated inhibition of beta-adrenergic activation of adenylate cyclase. ( Narayanan, N; Tucker, L, 1986)
"Neurochemical alterations in Alzheimer's disease (AD) include cholinergic neuronal loss in the nucleus basalis of Meynert (nbM) and a decrease in densities of the M2 muscarinic receptor subtype in areas related to learning and memory."1.43Activity of muscarinic, galanin and cannabinoid receptors in the prodromal and advanced stages in the triple transgenic mice model of Alzheimer's disease. ( Giménez-Llort, L; LaFerla, FM; Lombardero, L; Manuel, I; Rodríguez-Puertas, R, 2016)
"The study of late-onset/age-related Alzheimer's disease (AD)(sporadic AD, 95% of AD cases) has been hampered by a paucity of animal models."1.42Characterization of Aldh2 (-/-) mice as an age-related model of cognitive impairment and Alzheimer's disease. ( Andrew, RD; Bennett, BM; D'Souza, Y; Elharram, A; Soon-Shiong, R, 2015)
"1 µM carbachol was ∼4 times greater in adult than in neonatal nasal glands."1.37Defective fluid secretion from submucosal glands of nasal turbinates from CFTR-/- and CFTR (ΔF508/ΔF508) pigs. ( Cho, HJ; Joo, NS; Wine, JJ, 2011)
"Bronchi from eight cases of sudden infant death syndrome (SIDS) were also studied."1.30Effect of transmural pressure on preloads and collapse of immature bronchi. ( McFawn, PK; Mitchell, HW, 1997)
"Atropine pretreatment completely prevented a supramaximal dose of carbachol from inducing ciliary muscle contraction in either vector."1.29Age does not affect contractile responses of the isolated rhesus monkey ciliary muscle to muscarinic agonists. ( Flügel, C; Kaufman, PL; Poyer, JF, 1993)
"Diarrhea is induced when NSP4, acting as a viral enterotoxin, triggers a signal transduction pathway."1.29Age-dependent diarrhea induced by a rotaviral nonstructural glycoprotein. ( Ball, JM; Estes, MK; Morris, AP; Tian, P; Zeng, CQ, 1996)
" Interestingly, the VIP receptor antagonist [d-parachloro-Phe6,Leu17[VIP shifted the dose-response curve for carbachol significantly to the right, indicating inhibition of phosphoinositide hydrolysis."1.28Neuropeptide modulation of muscarinic receptors and function in cerebral cortex of young and senescent rats. ( Pedigo, NW; Rice, MA, 1992)
"For patients with Alzheimer's disease, no correlation was obtained between age and S."1.28[Changes in DNA synthesis in lymphocytes induced by carbachol via muscarinic acetylcholine receptor in relation to aging and Alzheimer's disease in females]. ( Furukawa, Y, 1992)
"Carbachol was effective in stimulating the secretion of pepsin as early as 12 h after birth."1.27Ontogeny of gastric mucosal muscarinic receptor and sensitivity to carbachol. ( Johnson, LR; Seidel, ER, 1984)
" Young males showed greater responsiveness to both drugs than young females, this being reflected in higher maxima of the dose-response curves obtained for the males."1.27The responsiveness of human eccrine sweat glands to choline and carbachol. Application to the study of peripheral cholinergic functioning in Alzheimer-type dementia. ( Bradshaw, CM; Lamb, K; Szabadi, E, 1983)
"oxotremorine) were applied."1.27Age-related decrements in the muscarinic enhancement of K+-evoked release of endogenous striatal dopamine: an indicator of altered cholinergic-dopaminergic reciprocal inhibitory control in senescence. ( Dalton, TK; Hunt, WA; Joseph, JA, 1988)
" Comparison of the dependence of the turnover on carbamoylcholine concentration revealed that in neonates, the dose-response curve was shifted to the left, giving a half-maximal effect at concentrations approximately tenfold lower than that in the adult."1.27Enhanced coupling of neonatal muscarinic receptors in rat brain to phosphoinositide turnover. ( Agranoff, BW; Fisher, SK; Heacock, AM, 1987)

Research

Studies (192)

TimeframeStudies, this research(%)All Research%
pre-199046 (23.96)18.7374
1990's95 (49.48)18.2507
2000's26 (13.54)29.6817
2010's22 (11.46)24.3611
2020's3 (1.56)2.80

Authors

AuthorsStudies
Phelps, C1
Chess-Williams, R1
Moro, C1
Hardy, CC1
Keilich, SR1
Harrison, AG1
Knight, BE1
Baker, DS1
Smith, PP1
Biwer, LA1
Askew-Page, HR1
Hong, K1
Milstein, J1
Johnstone, SR1
Macal, E1
Good, ME1
Bagher, P1
Sonkusare, SK1
Isakson, BE1
Nishikawa, N1
Chakrabarty, B1
Kitney, D1
Jabr, R1
Kanai, A1
Fry, C1
Demirtaş Şahin, T1
Yazir, Y1
Utkan, T2
Gacar, G1
Furat Rençber, S1
Gocmez, SS1
Moullé, VS1
Tremblay, C1
Castell, AL1
Vivot, K1
Ethier, M1
Fergusson, G1
Alquier, T1
Ghislain, J1
Poitout, V1
Vahabi, B1
Sellers, DJ1
Bijos, DA1
Drake, MJ1
Kanak, DJ1
Rose, GM1
Zaveri, HP1
Patrylo, PR1
Burmeister, DM1
AbouShwareb, T2
Bergman, CR1
Andersson, KE2
Christ, GJ1
Kirschstein, T1
Protzel, C1
Porath, K1
Sellmann, T1
Köhling, R1
Hakenberg, OW1
Sui, G1
Fry, CH1
Montgomery, B1
Roberts, M1
Wu, R1
Wu, C1
Zefirov, TL1
Ziyatdinova, NI1
Zefirov, AL1
D'Souza, Y1
Elharram, A1
Soon-Shiong, R1
Andrew, RD1
Bennett, BM1
Durlu-Kandilci, NT1
Denizalti, M1
Sahin-Erdemli, I1
Kendig, DM1
Ets, HK1
Moreland, RS1
Yaniv, Y1
Ahmet, I1
Tsutsui, K1
Behar, J1
Moen, JM1
Okamoto, Y1
Guiriba, TR1
Liu, J1
Bychkov, R1
Lakatta, EG1
Manuel, I1
Lombardero, L1
LaFerla, FM1
Giménez-Llort, L1
Rodríguez-Puertas, R1
Dricks, S1
Salameh, A1
Dhein, S1
Fleischmann, B1
Grohe, C1
Hescheler, J1
Linz, KW1
Meyer, R1
Zhao, W1
Turner, C1
Mathis, C1
Bennett, C1
Sonntag, WE1
Christ, G1
Maselli, MA1
Trisolini, P1
Demma, I1
Pezzolla, F1
De Ponti, F1
Cho, HJ1
Joo, NS1
Wine, JJ1
Owen, SJ1
Massa, HH1
Rose'Meyer, RB1
Ribeiro, RA1
Batista, TM1
Coelho, FM1
Boschero, AC2
Lopes, GS1
Carneiro, EM1
Scridon, A1
Gallet, C1
Arisha, MM1
Oréa, V1
Chapuis, B1
Li, N1
Tabib, A1
Christé, G1
Barrès, C1
Julien, C1
Chevalier, P1
Noble, K1
Wray, S1
Böhm, D1
Schwegler, H1
Kotthaus, L1
Nayernia, K1
Rickmann, M1
Köhler, M1
Rosenbusch, J1
Engel, W1
Flügge, G1
Burfeind, P1
Lluel, P2
Deplanne, V1
Heudes, D2
Bruneval, P2
Palea, S2
Walcott, B1
Matthews, G1
Brink, P1
Tugay, M1
Yildiz, F1
Gacar, N1
Ulak, G1
Erden, F1
Sakai, Y1
Masuda, H1
Kihara, K1
Kurosaki, E1
Yamauchi, Y1
Azuma, H1
Rossi, MA1
Mash, DC2
deToledo-Morrell, L1
Nakajima, E1
Nakajima, T1
Minagawa, Y1
Shearer, TR1
Azuma, M1
Vreugdenhil, M1
Toescu, EC1
Rosa, EF1
Silva, AC1
Ihara, SS1
Mora, OA1
Aboulafia, J1
Nouailhetas, VL1
Schneider, T1
Hein, P1
Michel-Reher, MB1
Michel, MC1
Yono, M2
Latifpour, J1
Yoshida, M2
Ueda, S2
Alves, M1
Cunha, DA1
Calegari, VC1
Saad, MJ1
Velloso, LA1
Rocha, EM1
Martin, SR1
Emanuel, K1
Sears, CE1
Zhang, YH1
Casadei, B1
Persson-Sjögren, S1
Forsgren, S1
Lindström, P1
Lai, HH1
Boone, TB1
Thompson, TC1
Smith, CP1
Somogyi, GT1
Yousif, MH1
Kehinde, EO1
Benter, IF1
Baumeister, M1
Wendt, M1
Glasser, A2
Ito, H2
Hoopes, MT2
Roth, GS10
Baum, BJ4
Douglas, JS1
Duncan, PG1
Mukhopadhyay, A1
Dumont, Y1
Côté, B1
Larose, L1
Poirier, G1
Morisset, J1
Bodner, L1
Gee, M1
Ikeno, T1
Dickens, G1
Lloyd, T1
Guroff, G1
Muraki, T2
Nakadate, T1
Kato, R2
Seidel, ER1
Johnson, LR2
Nakagawa, H2
Paradelis, AG1
Triantaphyllidis, CJ1
Fidani, V1
Crassaris, LG1
Papadopoulos, AG1
Stavrakis, AO1
Ikezaki, M1
Lamb, K1
Bradshaw, CM1
Szabadi, E1
Salo, A1
Virta, E1
Uusitalo, H1
Sawaki, K1
Ambudkar, IS1
Kelly, JF3
Mason, RP2
Denisova, NA4
Joseph, JA10
Erat, S3
Howland, HC1
Balligand, JL1
Kelly, RA1
Marsden, PA1
Smith, TW1
Michel, T1
Wong, RO1
Shibata, S1
Tanaka, T1
Watanabe, S1
Parent, A1
Rowe, W1
Meaney, MJ2
Quirion, R2
Pintor, A3
Fortuna, S3
Michalek, H3
Cutler, R2
Yamagami, K3
Villalobos-Molina, R1
Aronica, E1
Dell'Albani, P1
Condorelli, DF1
Nicoletti, F1
Hack, N1
Balázs, R1
He, M1
McCarthy, KD1
Finney, MJ1
Forsberg, KI1
Atkinson, J1
Tatchum-Talom, R1
Corman, B2
Cox, DA1
Cohen, ML1
Kogire, M1
Ishizuka, J1
Parekh, D1
Greeley, GH1
Thompson, JC1
Su, N3
Narayanan, N4
Nalepa, I2
Chalecka-Franaszek, E1
Vetulani, J2
Poyer, JF1
Kaufman, PL3
Flügel, C1
Strosznajder, J2
Samochocki, M2
Duran, M1
Ogawa, K1
McLaren, J1
Schacht, J1
Pucéat, M1
Hilal-Dandan, R1
Strulovici, B1
Brunton, LL1
Brown, JH1
Stoll, S1
Hartmann, H2
Cohen, SA2
Müller, WE3
Osaka, T1
Joyner, RW2
Kumar, R2
Tandon, P3
Pope, C1
Padilla, S1
Tilson, HA2
Harry, GJ1
Florio, T1
Meucci, O1
Grimaldi, M1
Ventra, C1
Cocozza, E1
Avallone, A1
Postiglione, A1
Marino, A1
Schettini, G1
Undie, AS1
Friedman, E1
Tan, XX1
Castoldi, AF2
Manzo, L2
Costa, LG5
Ball, JM1
Tian, P1
Zeng, CQ1
Morris, AP1
Estes, MK1
Bevilacqua, JA1
Downes, CP1
Lowenstein, PR1
Narang, N1
Ayyagari, PV2
Gerber, M2
Crews, FT2
Akita, T1
Ignesti, G1
Pino, R1
Banchelli, G1
Ferrali, C1
Pirisino, R1
Raimondi, L1
Duan, J1
Moffat, MP1
Singh, AK1
Balduini, W4
Cattabeni, F1
Cantoni, O1
Villalobos-Molinas, R1
Strain, J1
McFawn, PK1
Mitchell, HW2
Mörk, AC1
Zhang, A1
Martinez, JR2
Roomans, GM1
Jay, TR1
Heald, KA1
Downing, R1
Auerbach, JM1
Segal, M1
Salih, MA1
Kalu, DN1
Smith, TC1
Büyükuysal, RL1
Ulus, IH1
Kiran, BK1
Preuss, JM3
Rigby, PJ1
Goldie, RG3
Erat, SA1
Giessler, C1
Wangemann, T1
Zerkowski, HR1
Brodde, OE1
Strata, F1
Oh, MM1
Power, JM1
Thompson, LT1
Moriearty, PL1
Disterhoft, JF1
Titmus, MJ1
Tsai, HJ1
Lima, R1
Udin, SB1
Diep, N1
Constantinou, CE1
Miyasaka, K1
Shinozaki, H1
Suzuki, S1
Sato, Y1
Kanai, S1
Masuda, M1
Jimi, A1
Nagata, A1
Matsui, T1
Noda, T1
Kono, A1
Funakoshi, A1
Tümer, N1
Broxson, CS1
LaRochelle, JS1
Scarpace, PJ1
Barras, M1
Grandadam, F1
Martin, DJ1
Powell, AR1
Reddix, RA1
Chow, FA1
Seidler, FJ1
McCook, EC1
Slotkin, TA1
Homma, Y1
Inadome, A1
Seshita, H1
Miyamoto, Y1
Murakami, S1
Kawabe, K1
Chamiot-Clerc, P1
Renaud, JF1
Safar, ME1
Bairam, A1
Néji, H1
Kinkead, R1
Marchal, F1
Hormuzdi, SG1
Pais, I1
LeBeau, FE1
Towers, SK1
Rozov, A1
Buhl, EH1
Whittington, MA1
Monyer, H1
Calviño, MA1
Peña, C1
Rodríguez de Lores Arnaiz, G1
Abdel-Latif, AA1
Nukari-Siltovuori, A1
Aronstam, RS1
Kellogg, C1
Abood, LG1
Gettys, TW1
Tanaka, I1
Taylor, IL1
Pedigo, NW1
Rice, MA1
Laitinen, JT1
Vakkuri, O1
Saavedra, JM1
Birk, E1
Riemer, RK1
Candura, SM1
Cher, DJ1
Padfield, PJ1
Jamieson, JD1
Henry, PJ1
Costa, PF1
Santos, AI1
Ribeiro, MA1
Longhurst, PA1
Eika, B1
Leggett, RE1
Levin, RM1
Anson, RM1
Furukawa, Y1
Potier, B1
Rascol, O1
Jazat, F1
Lamour, Y2
Dutar, P2
Mundy, WR1
Ali, SF1
Nanry, K1
Rogers, BC1
Mundy, W1
Ali, S1
Tilson, H1
Wills-Karp, M1
Ohnuki, T1
Nomura, Y1
Heynen, AJ1
Bilkey, DK1
Takayanagi, I1
Moriya, M1
Kizawa, Y1
Koike, K1
Shinkai, M1
Murakami, H1
Vannucchi, MG1
Goldman-Rakic, PS1
Melvin, JE1
O'Connell, AC1
Koek, L1
Bowen, WH1
Machida, N1
Abdallah, EA1
Pou, WS1
el-Fakahany, EE1
Kowatch, MA1
Maki, T1
Gabelt, BT1
Crawford, K1
Fulop, T2
Kekessy, D1
Foris, G2
Murphy, SD2
Semmekrot, B1
Chabardès, D1
Roseau, S1
Siaume-Perez, S1
Butlen, D1
Court, JA1
Keith, AB1
Kerwin, JM1
Perry, EK1
Bartolami, S1
Guiramand, J2
Lenoir, M1
Pujol, R1
Récasens, M2
Kennedy, RH1
Seifen, E1
Pietrzak, ER1
Wilce, PA1
Shanley, BC1
Sparrow, MP1
Minton, AP1
Sokolovsky, M2
Araujo, DM1
Lapchak, PA1
Collier, B1
Leung, YK1
Lee, PC1
Lebenthal, E1
Vermue, NA1
Den Hertog, A1
Mirels, L1
Kousvelari, E1
Böhm, M1
Diet, F1
Kemkes, B1
Wankerl, M1
Erdmann, E1
Nomoto, T1
Sassetti, I1
Dudek, SM1
Bear, MF1
Phillips, TE1
Phillips, TL1
Neutra, MR1
Rooney, TA1
Nahorski, SR1
Varga, Z1
Nagy, JT1
Ferguson, AV1
Turner, SL1
Cooper, KE1
Veale, WL1
Jobert, A1
Dalton, TK1
Hunt, WA1
Tucker, L1
Oka, M1
Kimura, A1
Ohuchi, T1
Heacock, AM1
Fisher, SK1
Agranoff, BW1
Davis, PB1
Byard, PJ1
Moscona-Amir, E1
Henis, YI1
Konopacki, J1
Bland, BH1
Roth, SH1
Maśliński, W1
Grabczewska, E1
Laskowska-Bozek, H1
Ryzewski, J1
Koretz, JF1
Bertasso, AM1
Neider, MW1
True-Gabelt, BA1
Camden, J1
Flynn, DD1
Sauder, RA1
McNicol, KJ1
Stecenko, AA1
Bering, B1
Mardini, IA1
Schlenker, EH1
Burbach, JA1
Baker, SP1
Marchand, S1
O'Neil, E1
Nelson, CA1
Posner, P1
Bromberg, BB1
Welch, MH1
Mackay, AV1
Stroganova, NP1
Marley, E1
Seller, TJ1

Other Studies

192 other studies available for carbachol and Aging

ArticleYear
Ageing influences detrusor contractions to prostaglandin, angiotensin, histamine and 5-HT (serotonin), independent to the Rho kinase and extracellular calcium pathways.
    Scientific reports, 2023, 10-23, Volume: 13, Issue:1

    Topics: Aging; Angiotensins; Animals; Calcium; Calcium, Dietary; Carbachol; Dinoprostone; Histamine; Muscle

2023
The aging bladder phenotype is not the direct consequence of bladder aging.
    Neurourology and urodynamics, 2019, Volume: 38, Issue:8

    Topics: Adrenergic beta-Agonists; Aging; Animals; Carbachol; Cholinergic Agonists; Electric Stimulation; Fem

2019
Endothelial calreticulin deletion impairs endothelial function in aged mice.
    American journal of physiology. Heart and circulatory physiology, 2020, 05-01, Volume: 318, Issue:5

    Topics: Aging; Animals; Calcium Signaling; Calreticulin; Carbachol; Endothelium, Vascular; Gene Deletion; Ma

2020
Stretch- and carbachol-induced ATP release from bladder wall preparations of young and aged mice.
    Neurourology and urodynamics, 2020, Volume: 39, Issue:6

    Topics: Adenosine Triphosphate; Aging; Animals; Carbachol; Male; Mice; Mucous Membrane; Muscarinic Agonists;

2020
TNF-α antagonism with etanercept enhances penile NOS expression, cavernosal reactivity, and testosterone levels in aged rats.
    Canadian journal of physiology and pharmacology, 2018, Volume: 96, Issue:2

    Topics: Aging; Animals; Biomarkers; Body Weight; Carbachol; Electric Stimulation; Endothelium, Vascular; Eta

2018
The autonomic nervous system regulates pancreatic β-cell proliferation in adult male rats.
    American journal of physiology. Endocrinology and metabolism, 2019, 08-01, Volume: 317, Issue:2

    Topics: Aging; Animals; Autonomic Nervous System; Blood Glucose; Carbachol; Cell Proliferation; Cells, Cultu

2019
Phasic contractions in urinary bladder from juvenile versus adult pigs.
    PloS one, 2013, Volume: 8, Issue:3

    Topics: Aging; Animals; Benzamides; Carbachol; Dose-Response Relationship, Drug; Female; Imatinib Mesylate;

2013
Altered network timing in the CA3-CA1 circuit of hippocampal slices from aged mice.
    PloS one, 2013, Volume: 8, Issue:4

    Topics: Aging; Animals; Brain Waves; CA1 Region, Hippocampal; CA3 Region, Hippocampal; Carbachol; In Vitro T

2013
Age-related alterations in regeneration of the urinary bladder after subtotal cystectomy.
    The American journal of pathology, 2013, Volume: 183, Issue:5

    Topics: Aging; Animals; Blood Vessels; Carbachol; Cell Proliferation; Collagen; Cystectomy; Female; In Vitro

2013
Age-dependent contribution of Rho kinase in carbachol-induced contraction of human detrusor smooth muscle in vitro.
    Acta pharmacologica Sinica, 2014, Volume: 35, Issue:1

    Topics: Aged; Aged, 80 and over; Aging; Carbachol; Female; Humans; Male; Middle Aged; Muscle Contraction; Mu

2014
Purinergic and muscarinic modulation of ATP release from the urothelium and its paracrine actions.
    American journal of physiology. Renal physiology, 2014, Feb-01, Volume: 306, Issue:3

    Topics: Adenosine Triphosphate; Aged; Aging; Animals; Brefeldin A; Calcium; Carbachol; Carbenoxolone; Exocyt

2014
Age-related peculiarities of inotropic response of rat myocardium to selective block of M1-cholinoreceptors.
    Bulletin of experimental biology and medicine, 2013, Volume: 155, Issue:6

    Topics: Age Factors; Aging; Animals; Carbachol; Cholinergic Agonists; Cholinergic Antagonists; Depression, C

2013
Characterization of Aldh2 (-/-) mice as an age-related model of cognitive impairment and Alzheimer's disease.
    Molecular brain, 2015, Apr-25, Volume: 8

    Topics: Aging; Aldehyde Dehydrogenase; Aldehyde Dehydrogenase, Mitochondrial; Aldehydes; Alzheimer Disease;

2015
Aging changes agonist induced contractile responses in permeabilized rat bladder.
    Age (Dordrecht, Netherlands), 2015, Volume: 37, Issue:4

    Topics: Aging; Animals; Calcium Signaling; Carbachol; Cholinergic Agonists; Escin; Female; Muscle Contractio

2015
Effect of type II diabetes on male rat bladder contractility.
    American journal of physiology. Renal physiology, 2016, 05-01, Volume: 310, Issue:9

    Topics: Adenosine Triphosphate; Aging; Animals; Carbachol; Diabetes Mellitus, Type 2; Electric Stimulation;

2016
Deterioration of autonomic neuronal receptor signaling and mechanisms intrinsic to heart pacemaker cells contribute to age-associated alterations in heart rate variability in vivo.
    Aging cell, 2016, Volume: 15, Issue:4

    Topics: Aging; Animals; Autonomic Nervous System; Carbachol; Heart Rate; Isoproterenol; Longevity; Mice, Inb

2016
Activity of muscarinic, galanin and cannabinoid receptors in the prodromal and advanced stages in the triple transgenic mice model of Alzheimer's disease.
    Neuroscience, 2016, 08-04, Volume: 329

    Topics: Aging; Alzheimer Disease; Animals; Autoradiography; Brain; Carbachol; Disease Models, Animal; Diseas

2016
Effects of neonatal stress on gamma oscillations in hippocampus.
    Scientific reports, 2016, 07-01, Volume: 6

    Topics: Aging; Animals; Animals, Newborn; Carbachol; Gamma Rays; Hippocampus; Immunohistochemistry; Interneu

2016
The aging heart: changes in the pharmacodynamic electrophysiological response to verapamil in aged rabbit hearts.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2010, Volume: 61, Issue:2

    Topics: Age Factors; Aging; Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Carbachol; Electrop

2010
Impaired bladder function in aging male rats.
    The Journal of urology, 2010, Volume: 184, Issue:1

    Topics: Aging; Animals; Carbachol; Electric Stimulation; Logistic Models; Male; Muscle, Smooth; Rats; Rats,

2010
Gender- and age-related differences in muscular and nerve-mediated responses in human colon.
    Digestive diseases and sciences, 2011, Volume: 56, Issue:2

    Topics: Aged; Aged, 80 and over; Aging; Atropine; Carbachol; Colon; Dose-Response Relationship, Drug; Electr

2011
Defective fluid secretion from submucosal glands of nasal turbinates from CFTR-/- and CFTR (ΔF508/ΔF508) pigs.
    PloS one, 2011, Volume: 6, Issue:8

    Topics: Aging; Animals; Animals, Newborn; Body Fluids; Carbachol; Colforsin; Cystic Fibrosis; Cystic Fibrosi

2011
Loss of adenosine A2B receptor mediated relaxant responses in the aged female rat bladder; effects of dietary phytoestrogens.
    Naunyn-Schmiedeberg's archives of pharmacology, 2012, Volume: 385, Issue:5

    Topics: Adenosine-5'-(N-ethylcarboxamide); Adrenergic beta-Agonists; Aging; Animals; Carbachol; Diet; Estrog

2012
Decreased β-cell insulin secretory function in aged rats due to impaired Ca(2+) handling.
    Experimental physiology, 2012, Volume: 97, Issue:9

    Topics: Aging; Animals; Blood Glucose; Calcium; Carbachol; Cyclic AMP-Dependent Protein Kinases; Diabetes Me

2012
Unprovoked atrial tachyarrhythmias in aging spontaneously hypertensive rats: the role of the autonomic nervous system.
    American journal of physiology. Heart and circulatory physiology, 2012, Aug-01, Volume: 303, Issue:3

    Topics: Age Factors; Aging; Animals; Autonomic Nervous System; Blood Pressure; Carbachol; Cholinergic Agonis

2012
The role of the sarcoplasmic reticulum in neonatal uterine smooth muscle: enhanced role compared to adult rat.
    The Journal of physiology, 2002, 12-01, Volume: 545, Issue:2

    Topics: Aging; Animals; Animals, Newborn; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Calci

2002
Disruption of PLC-beta 1-mediated signal transduction in mutant mice causes age-dependent hippocampal mossy fiber sprouting and neurodegeneration.
    Molecular and cellular neurosciences, 2002, Volume: 21, Issue:4

    Topics: Aging; Alternative Splicing; Animals; Carbachol; Chromosome Mapping; Disease Models, Animal; Epileps

2002
Age-related changes in urethrovesical coordination in male rats: relationship with bladder instability?
    American journal of physiology. Regulatory, integrative and comparative physiology, 2003, Volume: 284, Issue:5

    Topics: Adrenergic Agents; Aging; Animals; Carbachol; Male; Muscle Contraction; Muscle, Smooth; Phenylephrin

2003
Differences in stimulus induced calcium increases in lacrimal gland acinar cells from normal and NZB/NZW F1 female mice.
    Current eye research, 2002, Volume: 25, Issue:4

    Topics: Adrenergic alpha-Agonists; Aging; Animals; Calcium; Carbachol; Cholinergic Agonists; Electrophysiolo

2002
Age-related smooth muscle reactivity changes in the rat bladder: an in vitro study.
    Pharmacological research, 2003, Volume: 48, Issue:4

    Topics: Adenosine Triphosphate; Aging; Animals; Carbachol; Dose-Response Relationship, Drug; In Vitro Techni

2003
Involvement of increased arginase activity in impaired cavernous relaxation with aging in the rabbit.
    The Journal of urology, 2004, Volume: 172, Issue:1

    Topics: Aging; Animals; Arginase; Arginine; Carbachol; Cholinergic Agonists; Endothelium, Vascular; Male; Mu

2004
Spatial memory in aged rats is related to PKCgamma-dependent G-protein coupling of the M1 receptor.
    Neurobiology of aging, 2005, Volume: 26, Issue:1

    Topics: Age Factors; Aging; Analysis of Variance; Animals; Behavior, Animal; Binding, Competitive; Carbachol

2005
Contribution of ROCK in contraction of trabecular meshwork: proposed mechanism for regulating aqueous outflow in monkey and human eyes.
    Journal of pharmaceutical sciences, 2005, Volume: 94, Issue:4

    Topics: Aged; Aged, 80 and over; Aging; Animals; Aqueous Humor; Carbachol; Ciliary Body; DNA Primers; Eye; H

2005
Age-dependent reduction of gamma oscillations in the mouse hippocampus in vitro.
    Neuroscience, 2005, Volume: 132, Issue:4

    Topics: Age Factors; Aging; Animals; Carbachol; Cholinergic Agonists; Electric Stimulation; Excitatory Amino

2005
Habitual exercise program protects murine intestinal, skeletal, and cardiac muscles against aging.
    Journal of applied physiology (Bethesda, Md. : 1985), 2005, Volume: 99, Issue:4

    Topics: Aging; Animals; Body Weight; Carbachol; Heart; Ileum; Intestines; Lipid Peroxidation; Male; Mice; Mi

2005
Effects of ageing on muscarinic receptor subtypes and function in rat urinary bladder.
    Naunyn-Schmiedeberg's archives of pharmacology, 2005, Volume: 372, Issue:1

    Topics: Aging; Animals; Atropine; Benzofurans; Carbachol; Cholinergic Agonists; Cholinergic Antagonists; Dos

2005
Age-related alterations in the biochemical and functional properties of the bladder in type 2 diabetic GK rats.
    Journal of receptor and signal transduction research, 2005, Volume: 25, Issue:3

    Topics: Acetylcholine; Adenosine Triphosphate; Aging; Animals; Body Weight; Carbachol; Diabetes Complication

2005
Nuclear factor-kappaB and advanced glycation end-products expression in lacrimal glands of aging rats.
    The Journal of endocrinology, 2005, Volume: 187, Issue:1

    Topics: Aging; Animals; Carbachol; Glucose; Glycation End Products, Advanced; Immunohistochemistry; Insulin;

2005
Are myocardial eNOS and nNOS involved in the beta-adrenergic and muscarinic regulation of inotropy? A systematic investigation.
    Cardiovascular research, 2006, Apr-01, Volume: 70, Issue:1

    Topics: Adrenergic beta-Agonists; Aging; Animals; Carbachol; Cell Size; Cholinergic Agonists; Electric Stimu

2006
Vasoactive intestinal polypeptide and pituitary adenylate cyclase activating polypeptide: effects on insulin release in isolated mouse islets in relation to metabolic status and age.
    Neuropeptides, 2006, Volume: 40, Issue:4

    Topics: Aging; Animals; Carbachol; Energy Metabolism; Female; Insulin; Islets of Langerhans; Mice; Mice, Obe

2006
Using caveolin-1 knockout mouse to study impaired detrusor contractility and disrupted muscarinic activity in the aging bladder.
    Urology, 2007, Volume: 69, Issue:2

    Topics: Aging; Animals; Carbachol; Caveolin 1; Disease Models, Animal; Electric Stimulation; Male; Mice; Mic

2007
Different responses to angiotensin-(1-7) in young, aged and diabetic rabbit corpus cavernosum.
    Pharmacological research, 2007, Volume: 56, Issue:3

    Topics: Aging; Angiotensin I; Angiotensin II; Animals; Carbachol; Diabetes Mellitus, Experimental; Dose-Resp

2007
Edinger--Westphal stimulated accommodative dynamics in anesthetized, middle-aged rhesus monkeys.
    Experimental eye research, 2008, Volume: 86, Issue:1

    Topics: Accommodation, Ocular; Aging; Anesthesia, General; Animals; Carbachol; Electric Stimulation; Lens, C

2008
Adrenergic and cholinergic mediated glucose oxidation by rat parotid gland acinar cells during aging.
    Biochemical and biophysical research communications, 1981, Jan-15, Volume: 98, Issue:1

    Topics: Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Aging; Animals; Carbachol; Cell Aggregation; Ep

1981
The antagonism of histamine-induced tracheal and bronchial muscle contraction by diphenhydramine: effect of maturation.
    British journal of pharmacology, 1984, Volume: 83, Issue:3

    Topics: Aging; Animals; Bronchi; Carbachol; Diphenhydramine; Guinea Pigs; Histamine; Histamine Antagonists;

1984
Maturation of muscarinic agonist receptors in rat developing pancreas and its relation to maximal enzyme secretion.
    Life sciences, 1981, Dec-28, Volume: 29, Issue:26

    Topics: Aging; Amylases; Animals; Bethanechol Compounds; Carbachol; Female; Fetus; Kinetics; Male; Pancreas;

1981
Multiple transduction mechanisms are likely involved in calcium-mediated exocrine secretory events in rat parotid cells.
    The Journal of biological chemistry, 1983, Mar-10, Volume: 258, Issue:5

    Topics: Aging; Amylases; Animals; Calcium; Carbachol; Cell Aggregation; Epinephrine; Kinetics; Male; Parotid

1983
The receptor-mediated activation of tyrosine hydroxylation in the superior cervical ganglion of the rat.
    Journal of neurochemistry, 1981, Volume: 36, Issue:5

    Topics: Aging; Animals; Bucladesine; Carbachol; Dopamine; Ganglia, Spinal; Hydroxylation; Kinetics; Pterins;

1981
Developmental changes in the effect of morphine, epinephrine and carbachol on plasma cyclic nucleotide level in rats.
    European journal of pharmacology, 1983, Oct-28, Volume: 94, Issue:3-4

    Topics: Aging; Animals; Carbachol; Cyclic AMP; Cyclic GMP; D-Ala(2),MePhe(4),Met(0)-ol-enkephalin; Epinephri

1983
Ontogeny of gastric mucosal muscarinic receptor and sensitivity to carbachol.
    The American journal of physiology, 1984, Volume: 246, Issue:5 Pt 1

    Topics: Aging; Animals; Carbachol; Gastric Juice; Gastric Mucosa; Kinetics; Pepsin A; Rats; Rats, Inbred Str

1984
Age-dependent alterations in the formation of cyclic nucleotides caused by various agents in guinea-pig tracheal smooth muscle.
    The Tokushima journal of experimental medicine, 1983, Volume: 30, Issue:3-4

    Topics: Aging; Animals; Animals, Newborn; Carbachol; Guinea Pigs; In Vitro Techniques; Isoproterenol; Male;

1983
The influence of age on the distribution and activity of histamine receptors in the rat uterus.
    Methods and findings in experimental and clinical pharmacology, 1984, Volume: 6, Issue:2

    Topics: Aging; Animals; Carbachol; Cimetidine; Electric Stimulation; Female; Histamine; Pyrilamine; Rats; Ra

1984
Development of sensitivity to different secretagogues in the rat stomach.
    The American journal of physiology, 1983, Volume: 244, Issue:2

    Topics: Aging; Animals; Carbachol; Carboxy-Lyases; Corticosterone; Gastric Juice; Gastric Mucosa; Histamine;

1983
The responsiveness of human eccrine sweat glands to choline and carbachol. Application to the study of peripheral cholinergic functioning in Alzheimer-type dementia.
    European journal of clinical pharmacology, 1983, Volume: 24, Issue:1

    Topics: Adult; Aged; Aging; Alzheimer Disease; Carbachol; Choline; Dementia; Dose-Response Relationship, Dru

1983
Calcitonin gene-related peptide (CGRP) and its effects on protein release in vitro in the developing submandibular gland of the rat.
    Regulatory peptides, 1995, Jan-26, Volume: 55, Issue:2

    Topics: Aging; Animals; Calcitonin Gene-Related Peptide; Carbachol; Female; Immunohistochemistry; Male; Nerv

1995
Decreased m3-muscarinic and alpha 1-adrenergic receptor stimulation of PIP2 hydrolysis in parotid gland membranes from aged rats: defect in activation of G alpha q/11.
    Archives of biochemistry and biophysics, 1995, Oct-01, Volume: 322, Issue:2

    Topics: Adenylyl Cyclases; Adrenergic alpha-Agonists; Aging; Aluminum Compounds; Animals; Carbachol; Dose-Re

1995
Age-related impairment in striatal muscarinic cholinergic signal transduction is associated with reduced membrane bilayer width measured by small angle X-ray diffraction.
    Biochemical and biophysical research communications, 1995, Aug-24, Volume: 213, Issue:3

    Topics: Aging; Animals; Carbachol; Cell Membrane; Corpus Striatum; GTP Phosphohydrolases; Male; Neurons; Rat

1995
In vitro changes in back vertex distance of chick and pigeon lenses: species differences and the effects of aging.
    Vision research, 1995, Volume: 35, Issue:13

    Topics: Accommodation, Ocular; Aging; Animals; Biometry; Carbachol; Chickens; Columbidae; In Vitro Technique

1995
Control of cardiac muscle cell function by an endogenous nitric oxide signaling system.
    Proceedings of the National Academy of Sciences of the United States of America, 1993, Jan-01, Volume: 90, Issue:1

    Topics: Aging; Amino Acid Oxidoreductases; Animals; Animals, Newborn; Arginine; Carbachol; Cells, Cultured;

1993
Cholinergic regulation of [Ca2+]i during cell division and differentiation in the mammalian retina.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1995, Volume: 15, Issue:4

    Topics: Aging; Animals; Animals, Newborn; Calcium; Calcium Channel Blockers; Carbachol; Cell Differentiation

1995
Dissociation of striatal GTPase and dopamine release responses to muscarinic cholinergic agonists in F344 rats: influence of age and dietary manipulation.
    Journal of neurochemistry, 1995, Volume: 64, Issue:6

    Topics: Aging; Animals; Carbachol; Cholesterol; Cholinergic Agents; Corpus Striatum; Diet; Dopamine; GTP Pho

1995
Facilitatory effects of somatostatin on reduced uptake of 2-deoxyglucose in cerebral cortical and hippocampal slices from aged rats.
    European journal of pharmacology, 1994, Oct-14, Volume: 269, Issue:2

    Topics: Aging; Animals; Carbachol; Cerebral Cortex; Deoxyglucose; Hippocampus; In Vitro Techniques; Male; Ra

1994
Increased production of inositol phosphates and diacylglycerol in aged cognitively impaired rats after stimulation of muscarinic, metabotropic-glutamate and endothelin receptors.
    The Journal of pharmacology and experimental therapeutics, 1995, Volume: 272, Issue:3

    Topics: Aging; Animals; Behavior, Animal; Carbachol; Cognition Disorders; Cycloleucine; Diglycerides; Inosit

1995
Carbachol-induced accumulation of inositol phosphates and its modulation by excitatory amino acids in cortical slices of young and aged rats with down-regulation of muscarinic M-1 receptors.
    Neurochemical research, 1994, Volume: 19, Issue:10

    Topics: Aging; Analysis of Variance; Animals; Carbachol; Cerebral Cortex; Down-Regulation; Excitatory Amino

1994
Area specific alterations in muscarinic stimulated low Km GTPase activity in aging and Alzheimer's disease: implications for altered signal transduction.
    Brain research, 1994, Nov-21, Volume: 664, Issue:1-2

    Topics: Aged; Aged, 80 and over; Aging; Alzheimer Disease; Carbachol; Enzyme Activation; GTP Phosphohydrolas

1994
Mechanisms underlying developmental changes in the expression of metabotropic glutamate receptors in cultured cerebellar granule cells: homologous desensitization and interactive effects involving N-methyl-D-aspartate receptors.
    Molecular pharmacology, 1993, Volume: 44, Issue:5

    Topics: Aging; Animals; Carbachol; Cells, Cultured; Cerebellum; Glutamates; Glutamic Acid; Hydrolysis; N-Met

1993
Oligodendroglial signal transduction systems are developmentally regulated.
    Journal of neurochemistry, 1994, Volume: 63, Issue:2

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenosine Triphosphate; Aging; Animals; Animals, Newborn; Br

1994
Quantification of nasal involvement in a guinea pig plethysmograph.
    Journal of applied physiology (Bethesda, Md. : 1985), 1994, Volume: 76, Issue:4

    Topics: Aerosols; Aging; Airway Resistance; Anesthesia; Animals; Carbachol; Dose-Response Relationship, Drug

1994
Effect of chronic ANG I-converting enzyme inhibition on aging processes. III. Endothelial function of mesenteric arterial bed of rat.
    The American journal of physiology, 1994, Volume: 267, Issue:1 Pt 2

    Topics: Aging; Angiotensin-Converting Enzyme Inhibitors; Animals; Carbachol; Endothelium, Vascular; Indoles;

1994
Age-related alterations in sensitivity of muscarinic and serotonergic responses of guinea pig trachea to removal of extracellular Ca2+.
    European journal of pharmacology, 1994, Jun-13, Volume: 258, Issue:3

    Topics: Aging; Animals; Calcium; Carbachol; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Musc

1994
Effects of aging on gastrin and somatostatin secretion from isolated perfused rat stomach.
    Digestive diseases and sciences, 1993, Volume: 38, Issue:2

    Topics: Aging; Analysis of Variance; Animals; Bombesin; Carbachol; Dose-Response Relationship, Drug; Gastric

1993
Age related alteration in cholinergic but not alpha adrenergic response of rat coronary vasculature.
    Cardiovascular research, 1993, Volume: 27, Issue:2

    Topics: Adrenergic alpha-Agonists; Aging; Animals; Blood Pressure; Calcium; Carbachol; Coronary Vessels; Dos

1993
Effects of excitatory amino acids on inositol phosphate accumulation in slices of the cerebral cortex of young and aged rats.
    Neurochemical research, 1993, Volume: 18, Issue:5

    Topics: Aging; Amino Acids; Animals; Carbachol; Cerebral Cortex; Glutamates; Glutamic Acid; Inositol Phospha

1993
Age does not affect contractile responses of the isolated rhesus monkey ciliary muscle to muscarinic agonists.
    Current eye research, 1993, Volume: 12, Issue:5

    Topics: Aging; Animals; Atropine; Carbachol; Cells, Cultured; Ciliary Body; Culture Media; Ganglionic Stimul

1993
Aging diminishes serotonin-stimulated arachidonic acid uptake and cholinergic receptor-activated arachidonic acid release in rat brain cortex membrane.
    Journal of neurochemistry, 1994, Volume: 62, Issue:3

    Topics: Aging; Animals; Arachidonic Acid; Carbachol; Cerebral Cortex; Electric Stimulation; Membranes; Rats;

1994
Effect of aging on myo-inositol and phosphoinositide metabolism in the cochlear and vestibular sensory epithelia of the rat.
    Hearing research, 1994, Volume: 73, Issue:2

    Topics: Adenosine Triphosphate; Aging; Animals; Binding Sites; Carbachol; Cochlea; Epithelium; Hydrolysis; I

1994
Differential regulation of protein kinase C isoforms in isolated neonatal and adult rat cardiomyocytes.
    The Journal of biological chemistry, 1994, Jun-17, Volume: 269, Issue:24

    Topics: Aging; Animals; Animals, Newborn; Blotting, Western; Carbachol; Cell Membrane; Cells, Cultured; Cyto

1994
The potent free radical scavenger alpha-lipoic acid improves memory in aged mice: putative relationship to NMDA receptor deficits.
    Pharmacology, biochemistry, and behavior, 1993, Volume: 46, Issue:4

    Topics: Aging; Animals; Behavior, Animal; Brain Chemistry; Carbachol; Cognition; Dizocilpine Maleate; Female

1993
Postnatal decrease in muscarinic cholinergic influence on Ca2+ currents of rabbit ventricular cells.
    The American journal of physiology, 1993, Volume: 264, Issue:6 Pt 2

    Topics: Adenylate Cyclase Toxin; Aging; Animals; Animals, Newborn; Calcium; Calcium Channel Blockers; Carbac

1993
Developmental changes in carbachol-stimulated inositolphosphate release in pigmented rat retina.
    Current eye research, 1993, Volume: 12, Issue:5

    Topics: Aging; Animals; Carbachol; Dark Adaptation; Eye Proteins; Female; Inositol Phosphates; Male; Phospho

1993
Effect of acetyl-L-carnitine treatment on brain adenylate cyclase activity in young and aged rats.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 1993, Volume: 3, Issue:2

    Topics: Acetylcarnitine; Adenylyl Cyclases; Aging; Animals; Brain; Carbachol; Cerebral Cortex; Dopamine; Mal

1993
Diet restriction prevents aging-induced deficits in brain phosphoinositide metabolism.
    Journal of gerontology, 1993, Volume: 48, Issue:2

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Aging; Animals; Atropine; Brain; Carbach

1993
Interaction of ethanol with muscarinic receptor-stimulated phosphoinositide metabolism during the brain growth spurt in the rat: role of acetaldehyde.
    Neuroscience letters, 1993, Jun-25, Volume: 156, Issue:1-2

    Topics: 1-Propanol; Acetaldehyde; Aging; Aldehydes; Animals; Brain; Carbachol; Cerebellum; Cerebral Cortex;

1993
Effects of subchronic administration of pyritinol on receptor deficits and phosphatidylinositol metabolism in the brain of the aged mouse.
    Neuropharmacology, 1993, Volume: 32, Issue:2

    Topics: Aging; Animals; Brain; Brain Chemistry; Carbachol; Female; Kinetics; Mice; Neurons; Phosphatidylinos

1993
Age-dependent diarrhea induced by a rotaviral nonstructural glycoprotein.
    Science (New York, N.Y.), 1996, Apr-05, Volume: 272, Issue:5258

    Topics: Aging; Amino Acid Sequence; Animals; Calcium; Carbachol; Chlorides; Colforsin; Diarrhea; Enterotoxin

1996
Transiently selective activation of phosphoinositide turnover in layer V pyramidal neurons after specific mGluRs stimulation in rat somatosensory cortex during early postnatal development.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1995, Volume: 15, Issue:12

    Topics: Aging; Animals; Animals, Newborn; Autoradiography; Carbachol; Cycloleucine; Female; Lithium; Male; P

1995
Age-related loss of cholinergic-muscarinic coupling to PLC: comparison with changes in brain regional PLC subtypes mRNA distribution.
    Brain research, 1996, Feb-05, Volume: 708, Issue:1-2

    Topics: Aging; Animals; Base Sequence; Brain; Calcium; Carbachol; Enzyme Activation; Guanosine 5'-O-(3-Thiot

1996
Adenosine and carbachol are not equivalent in their effects on L-type calcium current in rabbit ventricular cells.
    Journal of molecular and cellular cardiology, 1996, Volume: 28, Issue:2

    Topics: Adenosine; Aging; Amino Acid Sequence; Animals; Animals, Newborn; Calcium Channels; Carbachol; Colfo

1996
Increased desensitization by picomolar phorbol ester of the endothelium-mediated effect of histamine in the perfused rat mesenteric bed.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 1996, Volume: 45, Issue:4

    Topics: Aging; Alkaloids; Animals; Carbachol; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzym

1996
Age-related changes in electrophysiological responses to muscarinic receptor stimulation in rat myocardium.
    Canadian journal of physiology and pharmacology, 1995, Volume: 73, Issue:10

    Topics: Action Potentials; Aging; Animals; Atrioventricular Node; Carbachol; Electrophysiology; Heart; Male;

1995
Carbachol-regulation of the expression of alpha i1-subunit of Gi and inositol-[1,4,5]-trisphosphate receptor in brain samples obtained from neonatal and adult rats.
    Comparative biochemistry and physiology. Part C, Pharmacology, toxicology & endocrinology, 1995, Volume: 112, Issue:2

    Topics: Aging; Animals; Animals, Newborn; Brain Chemistry; Calcium Channels; Carbachol; Dactinomycin; GTP-Bi

1995
Modulation of muscarinic receptor-stimulated phosphoinositide breakdown by sulfhydryl group modification is a general response in different rat brain regions and depends on the stage of brain development.
    Biochemistry and molecular biology international, 1996, Volume: 40, Issue:2

    Topics: Aging; Animals; Animals, Newborn; Brain; Carbachol; Cerebral Cortex; Corpus Striatum; Diamide; Dithi

1996
Cholesterol: a two-edged sword in brain aging.
    Free radical biology & medicine, 1997, Volume: 22, Issue:3

    Topics: Aging; Animals; Brain; Carbachol; Cholesterol; Corpus Striatum; Dopamine; Drug Synergism; Glutathion

1997
Effect of transmural pressure on preloads and collapse of immature bronchi.
    The European respiratory journal, 1997, Volume: 10, Issue:2

    Topics: Aging; Animals; Animals, Newborn; Biomechanical Phenomena; Bronchi; Bronchoscopy; Carbachol; Complia

1997
Chloride secretion in the submandibular gland of adult and early postnatal rats studied by X-ray microanalysis.
    Histochemistry and cell biology, 1996, Volume: 105, Issue:4

    Topics: Aging; Animals; Animals, Newborn; Calcium; Carbachol; Cell Nucleus; Chlorides; Cytoplasm; Cytoplasmi

1996
Effect of donor age on porcine insulin secretion.
    Transplantation proceedings, 1997, Volume: 29, Issue:4

    Topics: Aging; Animals; Carbachol; Cells, Cultured; Glucose; Insulin; Insulin Secretion; Islets of Langerhan

1997
Peroxide modulation of slow onset potentiation in rat hippocampus.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1997, Nov-15, Volume: 17, Issue:22

    Topics: Aging; Animals; Carbachol; Catalase; Cholinergic Fibers; Dose-Response Relationship, Drug; Electroph

1997
Uncoupling of muscarinic cholinergic phosphoinositide signals in senescent cerebral cortical and hippocampal membranes.
    Neurochemistry international, 1998, Volume: 32, Issue:1

    Topics: Aging; Animals; Calcium; Carbachol; Cell Membrane; Cerebral Cortex; Enzyme Activation; Guanosine 5'-

1998
Effects of age and food restriction on calcium signaling in parotid acinar cells of Fischer 344 rats.
    Aging (Milan, Italy), 1997, Volume: 9, Issue:6

    Topics: Aging; Animals; Bucladesine; Calcium; Carbachol; Cyclic AMP; Energy Intake; Epinephrine; Fluorescent

1997
Age-related alterations in pre-synaptic and receptor-mediated cholinergic functions in rat brain.
    Neurochemical research, 1998, Volume: 23, Issue:5

    Topics: Acetylcholine; Aging; Animals; Brain; Carbachol; Cerebral Cortex; Corpus Striatum; Hippocampus; In V

1998
Age and region-dependent contraction to alpha-adrenoceptor agonists in rat and guinea-pig isolated trachea.
    British journal of pharmacology, 1998, Volume: 123, Issue:8

    Topics: Adrenergic alpha-Agonists; Aging; Animals; Carbachol; Guinea Pigs; In Vitro Techniques; Male; Muscar

1998
Differential effect of aging on cholesterol modulation of carbachol-stimulated low-K(m) GTPase in striatal synaptosomes.
    Experimental gerontology, 1998, Volume: 33, Issue:3

    Topics: Aging; Animals; Carbachol; Cholesterol; Corpus Striatum; GTP Phosphohydrolases; Male; Membranes; Pho

1998
Age-dependent decrease in the negative inotropic effect of carbachol on isolated human right atrium.
    European journal of pharmacology, 1998, Sep-18, Volume: 357, Issue:2-3

    Topics: Adolescent; Adult; Aged; Aging; Carbachol; Child; Child, Preschool; Colforsin; Female; Heart Atria;

1998
Intrinsic oscillations in CA3 hippocampal pyramids: physiological relevance to theta rhythm generation.
    Hippocampus, 1998, Volume: 8, Issue:6

    Topics: 4-Aminopyridine; Aging; Animals; Animals, Newborn; Calcium; Calcium Channels; Carbachol; Cesium; Hip

1998
Metrifonate increases neuronal excitability in CA1 pyramidal neurons from both young and aging rabbit hippocampus.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1999, Mar-01, Volume: 19, Issue:5

    Topics: Action Potentials; Aging; Animals; Atropine; Carbachol; Cholinergic Agonists; Cholinesterase Inhibit

1999
Effects of choline and other nicotinic agonists on the tectum of juvenile and adult Xenopus frogs: a patch-clamp study.
    Neuroscience, 1999, Volume: 91, Issue:2

    Topics: Aging; Alkaloids; Animals; Axons; Azocines; Carbachol; Choline; Excitatory Postsynaptic Potentials;

1999
Age dependent response to exogenous estrogen on micturition, contractility and cholinergic receptors of the rat bladder.
    Life sciences, 1999, Volume: 64, Issue:23

    Topics: Aging; Animals; Carbachol; Cholinergic Agonists; Dose-Response Relationship, Drug; Estrogens; Female

1999
Disruption of cholecystokinin (CCK)-B receptor gene did not modify bile or pancreatic secretion or pancreatic growth: a study in CCK-B receptor gene knockout mice.
    Pancreas, 1999, Volume: 19, Issue:2

    Topics: Aging; Amylases; Animals; Bile; Carbachol; Female; Heterozygote; Homozygote; Mice; Mice, Knockout; O

1999
Age-related changes in muscarinic cholinoceptor function in guinea-pig and rat airways.
    Naunyn-Schmiedeberg's archives of pharmacology, 1999, Volume: 360, Issue:2

    Topics: Acetylcholine; Aging; Animals; Carbachol; Cholinesterase Inhibitors; Cricetinae; Inositol Phosphates

1999
Induction of tyrosine hydroxylase and neuropeptide Y by carbachol: modulation with age.
    The journals of gerontology. Series A, Biological sciences and medical sciences, 1999, Volume: 54, Issue:10

    Topics: Adrenal Medulla; Aging; Animals; Carbachol; Cold Temperature; Dopamine beta-Hydroxylase; Immunohisto

1999
Functional and morphological modifications of the urinary bladder in aging female rats.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2000, Volume: 278, Issue:4

    Topics: Adenosine Triphosphate; Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Aging; Animals; Arecoli

2000
Differential effects of maturation on nicotinic- and muscarinic receptor-induced ion secretion in guinea pig distal colon.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 2000, Volume: 224, Issue:3

    Topics: Aging; Animals; Atropine; Carbachol; Colon; Dimethylphenylpiperazinium Iodide; Electric Stimulation;

2000
Adolescent nicotine exposure alters cardiac autonomic responsiveness: beta-adrenergic and m2-muscarinic receptors and their linkage to adenylyl cyclase.
    Brain research, 2000, Sep-29, Volume: 878, Issue:1-2

    Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Aging; Animals; Animals, Newborn; Autonomic Nervous Sys

2000
Age-related changes in cholinergic and purinergic neurotransmission in human isolated bladder smooth muscles.
    Experimental gerontology, 2001, Volume: 36, Issue:1

    Topics: Adenosine Triphosphate; Aged; Aging; Atropine; Carbachol; Cholinergic Fibers; Drug Resistance; Elect

2001
Pulse pressure, aortic reactivity, and endothelium dysfunction in old hypertensive rats.
    Hypertension (Dallas, Tex. : 1979), 2001, Volume: 37, Issue:2

    Topics: Aging; Animals; Aorta; Aorta, Thoracic; Blood Pressure; Carbachol; Carotid Arteries; Dose-Response R

2001
Carbachol effect on carotid body dopamine in vitro release in response to hypoxia in adult and pup rabbit.
    Neuroscience research, 2001, Volume: 40, Issue:2

    Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Carbachol; Carotid Body; Cholinergic Agonists; Dopam

2001
Impaired electrical signaling disrupts gamma frequency oscillations in connexin 36-deficient mice.
    Neuron, 2001, Aug-16, Volume: 31, Issue:3

    Topics: Aging; Animals; Brain; Carbachol; Cerebral Cortex; Connexins; Electroencephalography; Gap Junction d

2001
An endogenous Na+, K+-ATPase inhibitor enhances phosphoinositide hydrolysis in neonatal but not in adult rat brain cortex.
    Neurochemical research, 2001, Volume: 26, Issue:11

    Topics: Aging; Amiloride; Animals; Animals, Newborn; Carbachol; Cerebral Cortex; Kinetics; Male; Ouabain; Ph

2001
Effects of neurotransmitters and neuropharmacological agents on phospholipid metabolism in the rabbit iris muscle.
    Advances in experimental medicine and biology, 1976, Volume: 72

    Topics: Acetylcholine; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Aging; Animals; Atropine; Ca

1976
Postnatal development of adrenergic and cholinergic sensitivity in the isolated rat atria.
    Experientia, 1977, Dec-15, Volume: 33, Issue:12

    Topics: Acetylcholine; Aging; Animals; Carbachol; Heart; Heart Atria; Isoproterenol; Male; Norepinephrine; P

1977
Development of muscarinic cholinergic receptors in inbred strains of mice: identification of receptor heterogeneity and relation to audiogenic seizure susceptibility.
    Brain research, 1979, Feb-23, Volume: 162, Issue:2

    Topics: Acoustic Stimulation; Aging; Animals; Animals, Newborn; Brain; Brain Stem; Carbachol; Cerebral Corte

1979
Modulation of pancreatic exocrine function in rodents by treatment with pancreatic polypeptide.
    Pancreas, 1992, Volume: 7, Issue:6

    Topics: Aging; Amylases; Animals; Carbachol; Cattle; Female; In Vitro Techniques; Male; Mice; Pancreas; Panc

1992
Enhanced chronotropic and inotropic responses of rat myocardium to cholinergic stimulus with aging.
    Canadian journal of physiology and pharmacology, 1992, Volume: 70, Issue:12

    Topics: Acetylcholine; Acetylcholinesterase; Aging; Animals; Carbachol; Heart; Heart Rate; In Vitro Techniqu

1992
Neuropeptide modulation of muscarinic receptors and function in cerebral cortex of young and senescent rats.
    European journal of pharmacology, 1992, Feb-13, Volume: 225, Issue:2

    Topics: Aging; Animals; Carbachol; Cerebral Cortex; Hemicholinium 3; In Vitro Techniques; Male; Neuropeptide

1992
Pineal muscarinic phosphoinositide responses: age-associated sensitization, agonist-induced desensitization and increase in melatonin release from cultured pineal glands.
    Neuroendocrinology, 1992, Volume: 55, Issue:5

    Topics: Aging; Animals; Carbachol; Culture Techniques; Inositol; Kinetics; Male; Melatonin; Phosphatidylinos

1992
Myocardial cholinergic signaling changes with age.
    Pediatric research, 1992, Volume: 31, Issue:6

    Topics: Aging; Animals; Binding, Competitive; Carbachol; Fetal Heart; In Vitro Techniques; Kinetics; Myocard

1992
Guanine nucleotide- and muscarinic agonist-dependent phosphoinositide metabolism in synaptoneurosomes from cerebral cortex of immature rats.
    Neurochemical research, 1992, Volume: 17, Issue:11

    Topics: Aging; Aluminum; Aluminum Chloride; Aluminum Compounds; Animals; Animals, Newborn; Carbachol; Cerebr

1992
Amylase release from streptolysin O permeabilized fetal pancreatic acini.
    The American journal of physiology, 1992, Volume: 262, Issue:4 Pt 1

    Topics: Aging; Amylases; Animals; Bacterial Proteins; Calcium; Carbachol; Cyclic AMP; Embryonic and Fetal De

1992
Influence of age on epithelium-dependent responsiveness of guinea-pig and rat tracheal smooth muscle to spasmogens.
    European journal of pharmacology, 1992, May-01, Volume: 228, Issue:1

    Topics: Acetylcholine; Aging; Analysis of Variance; Animals; Carbachol; Epithelium; Guinea Pigs; Histamine;

1992
Slow and medium afterhyperpolarizations in maturing rat hippocampal CA1 neurones.
    Neuroreport, 1992, Volume: 3, Issue:7

    Topics: Aging; Analysis of Variance; Animals; Carbachol; Colforsin; Female; Hippocampus; In Vitro Techniques

1992
Comparison of urinary bladder function in 6 and 24 month male and female rats.
    The Journal of urology, 1992, Volume: 148, Issue:5

    Topics: Adenosine Triphosphate; Aging; Animals; Carbachol; Collagen; Female; In Vitro Techniques; Male; Musc

1992
The effects of aging on muscarinic receptor/G-protein coupling in the rat hippocampus and striatum.
    Brain research, 1992, Dec-11, Volume: 598, Issue:1-2

    Topics: Aging; Animals; Binding, Competitive; Carbachol; Corpus Striatum; GTP-Binding Proteins; Hippocampus;

1992
[Changes in DNA synthesis in lymphocytes induced by carbachol via muscarinic acetylcholine receptor in relation to aging and Alzheimer's disease in females].
    Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics, 1992, Volume: 29, Issue:12

    Topics: Adult; Aged; Aging; Alzheimer Disease; Carbachol; Cells, Cultured; DNA; Female; Humans; Lymphocytes;

1992
Decrement of muscarinic receptor-stimulated low-KM GTPase in striatum and hippocampus from the aged rat.
    Brain research, 1992, Apr-03, Volume: 576, Issue:2

    Topics: Aging; Animals; Blotting, Western; Carbachol; Cell Membrane; Corpus Striatum; GTP Phosphohydrolases;

1992
Alterations in the properties of hippocampal pyramidal neurons in the aged rat.
    Neuroscience, 1992, Volume: 48, Issue:4

    Topics: Acetylcholine; Action Potentials; Aging; Analysis of Variance; Animals; Baclofen; Carbachol; Electri

1992
Carbachol-stimulated release of arachidonic acid and eicosanoids from brain cortex synaptoneurosome lipids of adult and aged rats.
    Advances in experimental medicine and biology, 1992, Volume: 318

    Topics: Aging; Animals; Arachidonic Acid; Carbachol; Cerebral Cortex; Eicosanoids; In Vitro Techniques; Lipi

1992
Age-dependent changes in receptor-stimulated phosphoinositide turnover in the rat hippocampus.
    Pharmacology, biochemistry, and behavior, 1991, Volume: 38, Issue:4

    Topics: Aging; Animals; Carbachol; Choline O-Acetyltransferase; GTP-Binding Proteins; Hippocampus; Kinetics;

1991
Age-related changes in receptor-mediated phosphoinositide hydrolysis in various regions of rat brain.
    Life sciences, 1991, Volume: 49, Issue:14

    Topics: Aging; Animals; Brain; Carbachol; Cerebral Cortex; Choline O-Acetyltransferase; Corpus Striatum; Ino

1991
Effects of age on muscarinic agonist-induced contraction and IP accumulation in airway smooth muscle.
    Life sciences, 1991, Volume: 49, Issue:14

    Topics: Aging; Animals; Carbachol; GTP-Binding Proteins; Guinea Pigs; Inositol Phosphates; Male; Muscle Cont

1991
M1 acetylcholine receptor-mediated phosphatidylinositol turnover in adult and senescent rat brain slices.
    Japanese journal of pharmacology, 1991, Volume: 57, Issue:4

    Topics: Aging; Animals; Brain; Carbachol; Cerebral Cortex; Corpus Striatum; Cyclic AMP; Female; GTP-Binding

1991
Induction of RSA-like oscillations in both the in-vitro and in-vivo hippocampus.
    Neuroreport, 1991, Volume: 2, Issue:7

    Topics: Aging; Animals; Carbachol; Glutamates; Glutamic Acid; Hippocampus; In Vitro Techniques; Male; Picrot

1991
Effect of ageing on response to nicotine in rabbit bronchial preparation.
    General pharmacology, 1991, Volume: 22, Issue:5

    Topics: Acetylcholine; Acetylcholinesterase; Aging; Animals; Atropine; Bronchi; Carbachol; Choline O-Acetylt

1991
Age-dependent decrease in the affinity of muscarinic M1 receptors in neocortex of rhesus monkeys.
    Proceedings of the National Academy of Sciences of the United States of America, 1991, Dec-15, Volume: 88, Issue:24

    Topics: Aging; Animals; Autoradiography; Binding, Competitive; Carbachol; Cerebral Cortex; Kinetics; Macaca

1991
Agonist-induced Ca2+ mobilization in the rat submandibular gland during aging and subsequent to chronic propranolol treatment.
    Mechanisms of ageing and development, 1991, Nov-15, Volume: 61, Issue:1

    Topics: Aging; Animals; Calcium; Carbachol; Female; In Vitro Techniques; Intracellular Fluid; Isoproterenol;

1991
[Effects of cooling on cholinergically-mediated contractions of tracheal muscle taken from immature and mature guinea pigs].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1991, Volume: 98, Issue:6

    Topics: Acetylcholine; Acetylcholinesterase; Age Factors; Aging; Animals; Carbachol; Cholinergic Fibers; Dos

1991
Aging does not alter muscarinic receptor-mediated inhibition of cyclic AMP formation in the striatum and hippocampus.
    Brain research, 1990, Nov-26, Volume: 534, Issue:1-2

    Topics: Aging; Animals; Carbachol; Corpus Striatum; Cyclic AMP; Hippocampus; Male; Organ Specificity; Rats;

1990
Selective cross-activation/inhibition of second messenger systems and the reduction of age-related deficits in the muscarinic control of dopamine release from perifused rat striata.
    Brain research, 1990, Dec-24, Volume: 537, Issue:1-2

    Topics: Aging; Animals; Arachidonic Acid; Arachidonic Acids; Biotransformation; Carbachol; Corpus Striatum;

1990
Outflow facility and its response to pilocarpine decline in aging rhesus monkeys.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1991, Volume: 109, Issue:6

    Topics: Accommodation, Ocular; Aging; Animals; Aqueous Humor; Carbachol; Ciliary Body; Macaca mulatta; Oculo

1991
Altered post-receptorial signal transduction mechanism under various stimulation in polymorphonuclear granulocytes of Alzheimer's disease.
    Mechanisms of ageing and development, 1990, Mar-15, Volume: 52, Issue:2-3

    Topics: Aged; Aged, 80 and over; Aging; Alzheimer Disease; Carbachol; Cyclic AMP; Cyclic GMP; Enkephalin, Me

1990
Potassium ions potentiate the muscarinic receptor-stimulated phosphoinositide metabolism in cerebral cortex slices: a comparison of neonatal and adult rats.
    Neurochemical research, 1990, Volume: 15, Issue:1

    Topics: Aging; Animals; Animals, Newborn; Carbachol; Cerebral Cortex; Female; Male; Norepinephrine; Phosphat

1990
Characterization of cholinergic muscarinic receptor-stimulated phosphoinositide metabolism in brain from immature rats.
    The Journal of pharmacology and experimental therapeutics, 1990, Volume: 253, Issue:2

    Topics: Aging; Animals; Animals, Newborn; Brain; Carbachol; Drug Interactions; Parasympatholytics; Parasympa

1990
Developmental neurotoxicity of ethanol: in vitro inhibition of muscarinic receptor-stimulated phosphoinositide metabolism in brain from neonatal but not adult rats.
    Brain research, 1990, Apr-02, Volume: 512, Issue:2

    Topics: Aging; Animals; Animals, Newborn; Brain; Carbachol; Ethanol; In Vitro Techniques; Phosphatidylinosit

1990
Developmental pattern of cyclic guanosine monophosphate production stimulated by atrial natriuretic peptide in glomeruli microdissected from kidneys of young rats.
    Pflugers Archiv : European journal of physiology, 1990, Volume: 416, Issue:5

    Topics: Aging; Animals; Animals, Newborn; Atrial Natriuretic Factor; Carbachol; Cyclic GMP; Kidney Glomerulu

1990
Fimbria-fornix lesions in aged rats cause increased carbachol-stimulated phosphoinositide hydrolysis in the hippocampus, but no change in muscarinic receptor binding.
    Brain research, 1990, Nov-05, Volume: 532, Issue:1-2

    Topics: Aging; Animals; Carbachol; Choline O-Acetyltransferase; Hippocampus; Hydrolysis; Male; Phosphatidyli

1990
Carbachol-induced inositol phosphate formation during rat cochlea development.
    Hearing research, 1990, Aug-15, Volume: 47, Issue:3

    Topics: Aging; Animals; Animals, Newborn; Carbachol; Cochlea; Dose-Response Relationship, Drug; Inositol Pho

1990
Aging: effects on chronotropic actions of muscarinic agonists in isolated rat atria.
    Mechanisms of ageing and development, 1990, Volume: 51, Issue:1

    Topics: Acetylcholine; Aging; Animals; Atrial Function; Carbachol; Heart Atria; Heart Rate; Male; Parasympat

1990
Interaction of chronic ethanol consumption and aging on brain muscarinic cholinergic receptors.
    The Journal of pharmacology and experimental therapeutics, 1990, Volume: 252, Issue:2

    Topics: Aging; Animals; Binding Sites; Brain; Carbachol; Ethanol; Male; Pirenzepine; Quinuclidinyl Benzilate

1990
Contraction of smooth muscle of pig airway tissues from before birth to maturity.
    Journal of applied physiology (Bethesda, Md. : 1985), 1990, Volume: 68, Issue:2

    Topics: Aging; Animals; Animals, Suckling; Bronchi; Carbachol; Fetus; Histamine; In Vitro Techniques; Muscle

1990
A model for the interaction of muscarinic receptors, agonists, and two distinct effector substances.
    Biochemistry, 1990, Feb-13, Volume: 29, Issue:6

    Topics: Aging; Animals; Batrachotoxins; Carbachol; Cell Membrane; Cells, Cultured; Guanylyl Imidodiphosphate

1990
Effects of aging on nicotinic and muscarinic autoreceptor function in the rat brain: relationship to presynaptic cholinergic markers and binding sites.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1990, Volume: 10, Issue:9

    Topics: Acetylcholine; Aging; Animals; Brain; Carbachol; Cerebral Cortex; Choline O-Acetyltransferase; Corpu

1990
Maturation of cholecystokinin receptors in pancreatic acini of rats.
    The American journal of physiology, 1986, Volume: 250, Issue:5 Pt 1

    Topics: Aging; Amylases; Animals; Bucladesine; Calcimycin; Carbachol; Kinetics; Pancreas; Rats; Rats, Inbred

1986
The prostaglandin response in guinea-pig taenia caeci and trachea smooth muscle of different ages.
    European journal of pharmacology, 1988, Mar-01, Volume: 147, Issue:2

    Topics: Aging; Animals; Carbachol; Cecum; Dinoprost; Dinoprostone; Guinea Pigs; In Vitro Techniques; Ion Cha

1988
Dissociation between c-fos gene expression and DNA synthesis in rat parotid glands.
    Archives of oral biology, 1989, Volume: 34, Issue:7

    Topics: Aging; Animals; Blotting, Northern; Carbachol; DNA; Epinephrine; Gene Expression; Isoproterenol; Mal

1989
Inotropic response to DPI 201-106 in the failing human heart.
    British journal of pharmacology, 1989, Volume: 98, Issue:1

    Topics: Adenosine; Adult; Aged; Aging; Calcium; Carbachol; Electric Stimulation; Female; Heart Failure; Hemo

1989
Developmental changes in the effects of carbachol and morphine on cGMP contents of plasma, heart, and lung of mice.
    Canadian journal of physiology and pharmacology, 1989, Volume: 67, Issue:10

    Topics: Aging; Animals; Carbachol; Cyclic GMP; Female; Heart; Lung; Male; Mice; Mice, Inbred ICR; Morphine;

1989
Increased responsiveness of the cerebral cortical phosphatidylinositol system to noradrenaline and carbachol in senescent rats.
    Neuroscience letters, 1989, Dec-15, Volume: 107, Issue:1-3

    Topics: Aging; Animals; Carbachol; Cerebral Cortex; Male; Norepinephrine; Phosphatidylinositols; Rats; Rats,

1989
Developmental changes in the chemosensitivity of rat brain synaptoneurosomes to excitatory amino acids, estimated by inositol phosphate formation.
    International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience, 1989, Volume: 7, Issue:3

    Topics: Aging; Animals; Aspartic Acid; Carbachol; Female; Frontal Lobe; Glutamates; Glutamic Acid; Inositol

1989
A biochemical correlate of the critical period for synaptic modification in the visual cortex.
    Science (New York, N.Y.), 1989, Nov-03, Volume: 246, Issue:4930

    Topics: Aging; Animals; Aspartic Acid; Carbachol; Cattle; Glutamates; Glutamic Acid; Ibotenic Acid; N-Methyl

1989
Cholinergic responsiveness of goblet cells during intestinal maturation.
    Biology of the neonate, 1989, Volume: 55, Issue:4-5

    Topics: Aging; Animals; Animals, Newborn; Carbachol; Female; Ileum; Intestinal Mucosa; Mucus; Organ Culture

1989
Postnatal ontogeny of agonist and depolarization-induced phosphoinositide hydrolysis in rat cerebral cortex.
    The Journal of pharmacology and experimental therapeutics, 1987, Volume: 243, Issue:1

    Topics: Aging; Animals; Arecoline; Calcium Channel Blockers; Carbachol; Cerebral Cortex; Hydrolysis; Male; N

1987
Studies on opsonized zymozan, FMLP, carbachol, PMA and A23187 stimulated respiratory burst of human PMNLs.
    Biochemistry international, 1988, Volume: 17, Issue:3

    Topics: Adult; Aging; Calcimycin; Carbachol; Humans; In Vitro Techniques; Male; N-Formylmethionine Leucyl-Ph

1988
Neurotransmitter effects on body temperature are modified with increasing age.
    Physiology & behavior, 1985, Volume: 34, Issue:6

    Topics: Aging; Animals; Body Temperature; Body Temperature Regulation; Carbachol; Dinoprostone; Dopamine; Hy

1985
Cerebral neocortical neurons in the aged rat: spontaneous activity, properties of pyramidal tract neurons and effect of acetylcholine and cholinergic drugs.
    Neuroscience, 1985, Volume: 16, Issue:4

    Topics: Acetylcholine; Aging; Animals; Carbachol; Glutamates; Glutamic Acid; Male; Parasympathomimetics; Pyr

1985
Age-related decrements in the muscarinic enhancement of K+-evoked release of endogenous striatal dopamine: an indicator of altered cholinergic-dopaminergic reciprocal inhibitory control in senescence.
    Brain research, 1988, Jun-28, Volume: 454, Issue:1-2

    Topics: Aging; Animals; Bethanechol; Bethanechol Compounds; Carbachol; Cholinergic Fibers; Corpus Striatum;

1988
Autonomic interactions in the aging heart: age-associated decrease in muscarinic cholinergic receptor mediated inhibition of beta-adrenergic activation of adenylate cyclase.
    Mechanisms of ageing and development, 1986, Volume: 34, Issue:3

    Topics: Adenylyl Cyclases; Aging; Animals; Atropine; Carbachol; Cell Membrane; Enzyme Activation; Guanosine

1986
Effect of age on the formation of cyclic nucleotides in guinea-pig tracheal smooth muscle in response to pharmacological agents.
    European journal of pharmacology, 1986, Jun-17, Volume: 125, Issue:2

    Topics: Aging; Alprostadil; Animals; Carbachol; Cholera Toxin; Colforsin; Cyclic AMP; Cyclic GMP; Guinea Pig

1986
Enhanced coupling of neonatal muscarinic receptors in rat brain to phosphoinositide turnover.
    Journal of neurochemistry, 1987, Volume: 48, Issue:6

    Topics: Aging; Animals; Animals, Newborn; Carbachol; Cerebral Cortex; Inositol; Phosphatidylinositols; Quinu

1987
Relationships among airway reactivity, pupillary alpha-adrenergic and cholinergic responsiveness, and age.
    Journal of applied physiology (Bethesda, Md. : 1985), 1988, Volume: 65, Issue:1

    Topics: Adolescent; Adult; Aged; Aging; Airway Resistance; Carbachol; Female; Humans; Male; Methacholine Chl

1988
Guanosine 5'-triphosphate binding protein (Gi) and two additional pertussis toxin substrates associated with muscarinic receptors in rat heart myocytes: characterization and age dependency.
    Biochemistry, 1988, Jul-12, Volume: 27, Issue:14

    Topics: Adenosine Diphosphate Ribose; Aging; Animals; Carbachol; Cells, Cultured; GTP-Binding Proteins; Guan

1988
The development of carbachol-induced EEG 'theta' examined in hippocampal formation slices.
    Brain research, 1988, Feb-01, Volume: 466, Issue:2

    Topics: Aging; Animals; Carbachol; Electroencephalography; Hippocampus; In Vitro Techniques; Male; Rats; Rat

1988
Expression of muscarinic cholinergic receptors during T cell maturation in the thymus.
    European journal of immunology, 1987, Volume: 17, Issue:7

    Topics: Aging; Animals; Animals, Newborn; Binding Sites; Carbachol; Cell Differentiation; Cortisone; Embryo,

1987
Slit-lamp studies of the rhesus monkey eye: II. Changes in crystalline lens shape, thickness and position during accommodation and aging.
    Experimental eye research, 1987, Volume: 45, Issue:2

    Topics: Accommodation, Ocular; Aging; Animals; Anterior Chamber; Carbachol; Electric Stimulation; Female; Hu

1987
42K spaces in submandibular gland of early postnatal rats: effects of carbachol and transport inhibitors.
    Experientia, 1986, Sep-15, Volume: 42, Issue:9

    Topics: Aging; Animals; Animals, Newborn; Biological Transport; Carbachol; Furosemide; Ouabain; Potassium; P

1986
Characterization of L-[3H]nicotine binding in human cerebral cortex: comparison between Alzheimer's disease and the normal.
    Journal of neurochemistry, 1986, Volume: 47, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Aging; Alzheimer Disease; Animals; Carbachol; Cerebral Cortex; Choli

1986
Effect of age on lung mechanics and airway reactivity in lambs.
    Journal of applied physiology (Bethesda, Md. : 1985), 1986, Volume: 61, Issue:6

    Topics: Aging; Animals; Carbachol; Citrates; Citric Acid; Female; Histamine; Lung; Lung Volume Measurements;

1986
Stereospecific 3H-QNB binding to human erythrocyte membranes associated with muscarinic cholinergic receptors.
    Journal of neural transmission, 1987, Volume: 68, Issue:1-2

    Topics: Adult; Aging; Animals; Atropine; Brain; Carbachol; Erythrocyte Membrane; Female; Guanylyl Imidodipho

1987
Effects of dystrophy and age on hamster tracheal smooth muscle function.
    Respiration physiology, 1986, Volume: 66, Issue:2

    Topics: Aging; Airway Resistance; Animals; Carbachol; Cricetinae; Histamine; In Vitro Techniques; Isoprotere

1986
Age-related changes in cardiac muscarinic receptors: decreased ability of the receptor to form a high affinity agonist binding state.
    Journal of gerontology, 1985, Volume: 40, Issue:2

    Topics: Aging; Animals; Body Weight; Carbachol; Guanylyl Imidodiphosphate; Heart; Male; Myocardium; Organ Si

1985
Lacrimal protein secretion: comparison of young and old rats.
    Experimental eye research, 1985, Volume: 40, Issue:2

    Topics: Aging; Animals; Atropine; Carbachol; Female; Lacrimal Apparatus; Male; Peroxidases; Proteins; Rats;

1985
The long-term regulation of tyrosine hydroxylase activity in cultured sympathetic ganglia: role of ganglionic noradrenaline content.
    British journal of pharmacology, 1974, Volume: 51, Issue:4

    Topics: Acetylesterase; Aging; Animals; Animals, Newborn; Bucladesine; Carbachol; Choline; Cyclic AMP; Cyclo

1974
[Some indices of the functioal condition of the cardiovascular system during experimental hypertension in animals of various ages].
    Kardiologiia, 1968, Volume: 8, Issue:8

    Topics: Aging; Animals; Arteries; Blood Pressure; Carbachol; Cardiomegaly; Cardiovascular System; Constricti

1968
Effects of cholinomimetic agents given into the brain of fowls.
    British journal of pharmacology, 1974, Volume: 51, Issue:3

    Topics: Acetylcholine; Aging; Animals; Behavior, Animal; Benzoates; Body Temperature; Carbachol; Cerebral Ve

1974